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Conserved domains on  [gi|116268105|ref|NP_689565|]
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protein FAM210A [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 124-211 1.90e-33

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


:

Pssm-ID: 429191  Cd Length: 88  Bit Score: 116.97  E-value: 1.90e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268105  124 QRFKKTFRQYGKVLIPVHLITSGVWFGTFYYAALKGVNVVPFLELIGLPDSVVSILKNSQSGNALTAYALFKIATPARYT 203
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSSGVDVIALLEKLGISDNKVESLSASGWGTFAIAYAIHKIAAPIRLP 80


                  ....*...
gi 116268105  204 VTLGGTSV 211
Cdd:pfam06916  81 ITLALTPL 88
YtxH pfam12732
YtxH-like protein; This family of proteins is found in bacteria. Proteins in this family are ...
 237-272 1.66e-03

YtxH-like protein; This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.


:

Pssm-ID: 432750 [Multi-domain]  Cd Length: 71  Bit Score: 36.43  E-value: 1.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 116268105  237 EETKELITEKMEETKDRLTEKLQETKEKVS-FKKKVE 272
Cdd:pfam12732  24 KETRKDLKDKAEDLKDKAKDLAEEAKEKAEdLKEKVK 60
 
Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 124-211 1.90e-33

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


Pssm-ID: 429191  Cd Length: 88  Bit Score: 116.97  E-value: 1.90e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268105  124 QRFKKTFRQYGKVLIPVHLITSGVWFGTFYYAALKGVNVVPFLELIGLPDSVVSILKNSQSGNALTAYALFKIATPARYT 203
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSSGVDVIALLEKLGISDNKVESLSASGWGTFAIAYAIHKIAAPIRLP 80


                  ....*...
gi 116268105  204 VTLGGTSV 211
Cdd:pfam06916  81 ITLALTPL 88
YtxH pfam12732
YtxH-like protein; This family of proteins is found in bacteria. Proteins in this family are ...
 237-272 1.66e-03

YtxH-like protein; This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.


Pssm-ID: 432750 [Multi-domain]  Cd Length: 71  Bit Score: 36.43  E-value: 1.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 116268105  237 EETKELITEKMEETKDRLTEKLQETKEKVS-FKKKVE 272
Cdd:pfam12732  24 KETRKDLKDKAEDLKDKAKDLAEEAKEKAEdLKEKVK 60
 
Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 124-211 1.90e-33

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


Pssm-ID: 429191  Cd Length: 88  Bit Score: 116.97  E-value: 1.90e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116268105  124 QRFKKTFRQYGKVLIPVHLITSGVWFGTFYYAALKGVNVVPFLELIGLPDSVVSILKNSQSGNALTAYALFKIATPARYT 203
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSSGVDVIALLEKLGISDNKVESLSASGWGTFAIAYAIHKIAAPIRLP 80


                  ....*...
gi 116268105  204 VTLGGTSV 211
Cdd:pfam06916  81 ITLALTPL 88
YtxH pfam12732
YtxH-like protein; This family of proteins is found in bacteria. Proteins in this family are ...
 237-272 1.66e-03

YtxH-like protein; This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.


Pssm-ID: 432750 [Multi-domain]  Cd Length: 71  Bit Score: 36.43  E-value: 1.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 116268105  237 EETKELITEKMEETKDRLTEKLQETKEKVS-FKKKVE 272
Cdd:pfam12732  24 KETRKDLKDKAEDLKDKAKDLAEEAKEKAEdLKEKVK 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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