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Conserved domains on  [gi|116242518|sp|Q6UWB1|]
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RecName: Full=Interleukin-27 receptor subunit alpha; Short=IL-27 receptor subunit alpha; Short=IL-27R subunit alpha; Short=IL-27R-alpha; Short=IL-27RA; AltName: Full=Cytokine receptor WSX-1; AltName: Full=Cytokine receptor-like 1; AltName: Full=Type I T-cell cytokine receptor; Short=TCCR; AltName: Full=ZcytoR1; Flags: Precursor

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 321-394 8.15e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 38.55  E-value: 8.15e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116242518  321 SAPRSVAVSSIaGSTELLVTWQP---GPGEPLEHVVDWARDGDPlEKLNWVRLPPGNLSALLPGnFTVGVPYRITVT 394
Cdd:pfam00041   1 SAPSNLTVTDV-TSTSLTVSWTPppdGNGPITGYEVEYRPKNSG-EPWNEITVPGTTTSVTLTG-LKPGTEYEVRVQ 74
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 128-228 1.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242518 128 PNAPRlgpDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPelKTIPLTPVEIQDLELATGY--KVY 205
Cdd:cd00063    1 PSPPT---NLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEV--TPGSETSYTLTGLKPGTEYefRVR 75

                         90       100
                 ....*....|....*....|...
gi 116242518 206 GRCRMEkeedlWGEWSPILSFQT 228
Cdd:cd00063   76 AVNGGG-----ESPPSESVTVTT 93
 
Name Accession Description Interval E-value
fn3 pfam00041
Fibronectin type III domain;
321-394 8.15e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 38.55  E-value: 8.15e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116242518  321 SAPRSVAVSSIaGSTELLVTWQP---GPGEPLEHVVDWARDGDPlEKLNWVRLPPGNLSALLPGnFTVGVPYRITVT 394
Cdd:pfam00041   1 SAPSNLTVTDV-TSTSLTVSWTPppdGNGPITGYEVEYRPKNSG-EPWNEITVPGTTTSVTLTG-LKPGTEYEVRVQ 74
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 128-228 1.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242518 128 PNAPRlgpDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPelKTIPLTPVEIQDLELATGY--KVY 205
Cdd:cd00063    1 PSPPT---NLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEV--TPGSETSYTLTGLKPGTEYefRVR 75

                         90       100
                 ....*....|....*....|...
gi 116242518 206 GRCRMEkeedlWGEWSPILSFQT 228
Cdd:cd00063   76 AVNGGG-----ESPPSESVTVTT 93
 
Name Accession Description Interval E-value
fn3 pfam00041
Fibronectin type III domain;
321-394 8.15e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 38.55  E-value: 8.15e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116242518  321 SAPRSVAVSSIaGSTELLVTWQP---GPGEPLEHVVDWARDGDPlEKLNWVRLPPGNLSALLPGnFTVGVPYRITVT 394
Cdd:pfam00041   1 SAPSNLTVTDV-TSTSLTVSWTPppdGNGPITGYEVEYRPKNSG-EPWNEITVPGTTTSVTLTG-LKPGTEYEVRVQ 74
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 128-228 1.05e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242518 128 PNAPRlgpDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPelKTIPLTPVEIQDLELATGY--KVY 205
Cdd:cd00063    1 PSPPT---NLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVEV--TPGSETSYTLTGLKPGTEYefRVR 75

                         90       100
                 ....*....|....*....|...
gi 116242518 206 GRCRMEkeedlWGEWSPILSFQT 228
Cdd:cd00063   76 AVNGGG-----ESPPSESVTVTT 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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