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Conserved domains on  [gi|116242480|sp|Q8N461|]
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RecName: Full=F-box/LRR-repeat protein 16; AltName: Full=F-box and leucine-rich repeat protein 16

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
F-box_FBXL16 cd22127
F-box domain found in F-box/LRR-repeat protein 16 (FBXL16) and similar proteins; FBXL16, also ...
 95-136 3.90e-24

F-box domain found in F-box/LRR-repeat protein 16 (FBXL16) and similar proteins; FBXL16, also called F-box and leucine-rich repeat protein 16, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It acts as a repressor of one of the earliest steps in the cardiogenic lineage: FLK1+ progenitor formation. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


:

Pssm-ID: 438899  Cd Length: 42  Bit Score: 94.31  E-value: 3.90e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 116242480  95 LATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAG 136
Cdd:cd22127    1 LLLDEKFLNRLFWYFSPCERCVLAQVCKKWRDVLYQPKFWRG 42
AMN1 super family cl39120
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ...
 201-413 3.47e-18

Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.


The actual alignment was detected with superfamily member cd09293:

Pssm-ID: 187754 [Multi-domain]  Cd Length: 226  Bit Score: 83.53  E-value: 3.47e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 201 KRSTITDAGLEvMLEQM--QGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAy 278
Cdd:cd09293   10 KLGQITQSNIS-QLLRIlhSGLEWLELYMCPISDPPLDQLSNCNKLKKLILPGSKLIDDEGLIALAQSCPNLQVLDLRA- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 279 hvtdtalayftarqghsthtlrllsCWEITNHGVVNVVHSLPNLTALSLS---GCSKVTDDGVELVAENLRKLRSLDLSW 355
Cdd:cd09293   88 -------------------------CENITDSGIVALATNCPKLQTINLGrhrNGHLITDVSLSALGKNCTFLQTVGFAG 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116242480 356 CpRITDMAL-EYVACDLHRLEELVLDRCVRITDTGLSYLSTMSS---LRSLYLRWCCQVQDF 413
Cdd:cd09293  143 C-DVTDKGVwELASGCSKSLERLSLNNCRNLTDQSIPAILASNYfpnLSVLEFRGCPLITDF 203
 
Name Accession Description Interval E-value
F-box_FBXL16 cd22127
F-box domain found in F-box/LRR-repeat protein 16 (FBXL16) and similar proteins; FBXL16, also ...
 95-136 3.90e-24

F-box domain found in F-box/LRR-repeat protein 16 (FBXL16) and similar proteins; FBXL16, also called F-box and leucine-rich repeat protein 16, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It acts as a repressor of one of the earliest steps in the cardiogenic lineage: FLK1+ progenitor formation. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438899  Cd Length: 42  Bit Score: 94.31  E-value: 3.90e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 116242480  95 LATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAG 136
Cdd:cd22127    1 LLLDEKFLNRLFWYFSPCERCVLAQVCKKWRDVLYQPKFWRG 42
AMN1 cd09293
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ...
 201-413 3.47e-18

Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.


Pssm-ID: 187754 [Multi-domain]  Cd Length: 226  Bit Score: 83.53  E-value: 3.47e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 201 KRSTITDAGLEvMLEQM--QGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAy 278
Cdd:cd09293   10 KLGQITQSNIS-QLLRIlhSGLEWLELYMCPISDPPLDQLSNCNKLKKLILPGSKLIDDEGLIALAQSCPNLQVLDLRA- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 279 hvtdtalayftarqghsthtlrllsCWEITNHGVVNVVHSLPNLTALSLS---GCSKVTDDGVELVAENLRKLRSLDLSW 355
Cdd:cd09293   88 -------------------------CENITDSGIVALATNCPKLQTINLGrhrNGHLITDVSLSALGKNCTFLQTVGFAG 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116242480 356 CpRITDMAL-EYVACDLHRLEELVLDRCVRITDTGLSYLSTMSS---LRSLYLRWCCQVQDF 413
Cdd:cd09293  143 C-DVTDKGVwELASGCSKSLERLSLNNCRNLTDQSIPAILASNYfpnLSVLEFRGCPLITDF 203
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 205-355 2.43e-07

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 52.87  E-value: 2.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 205 ITDAGLEVMLEQMQG---VVRLELSGcNDFTEAG---LWSSLSAR--ITSLSVSDcINVADDAIAAISQLLPN---LAEL 273
Cdd:COG5238  248 IGDEGVIALAEALKNnttVETLYLSG-NQIGAEGaiaLAKALQGNttLTSLDLSV-NRIGDEGAIALAEGLQGnktLHTL 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 274 SLQAYHVTDT-ALAYFTARQGHST-HTLRLLSCwEITNHGVVNVVHSL---PNLTALSLSGcSKVTDDGVELVAENLR-- 346
Cdd:COG5238  326 NLAYNGIGAQgAIALAKALQENTTlHSLDLSDN-QIGDEGAIALAKYLegnTTLRELNLGK-NNIGKQGAEALIDALQtn 403


                 ....*....
gi 116242480 347 KLRSLDLSW 355
Cdd:COG5238  404 RLHTLILDG 412
LRR_CC smart00367
Leucine-rich repeat - CC (cysteine-containing) subfamily;
347-368 4.96e-03

Leucine-rich repeat - CC (cysteine-containing) subfamily;


Pssm-ID: 197685 [Multi-domain]  Cd Length: 26  Bit Score: 34.30  E-value: 4.96e-03
                           10        20
                   ....*....|....*....|..
gi 116242480   347 KLRSLDLSWCPRITDMALEYVA 368
Cdd:smart00367   3 NLRELDLSGCTNITDEGLQALA 24
 
Name Accession Description Interval E-value
F-box_FBXL16 cd22127
F-box domain found in F-box/LRR-repeat protein 16 (FBXL16) and similar proteins; FBXL16, also ...
 95-136 3.90e-24

F-box domain found in F-box/LRR-repeat protein 16 (FBXL16) and similar proteins; FBXL16, also called F-box and leucine-rich repeat protein 16, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It acts as a repressor of one of the earliest steps in the cardiogenic lineage: FLK1+ progenitor formation. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438899  Cd Length: 42  Bit Score: 94.31  E-value: 3.90e-24
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 116242480  95 LATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAG 136
Cdd:cd22127    1 LLLDEKFLNRLFWYFSPCERCVLAQVCKKWRDVLYQPKFWRG 42
AMN1 cd09293
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ...
 201-413 3.47e-18

Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.


Pssm-ID: 187754 [Multi-domain]  Cd Length: 226  Bit Score: 83.53  E-value: 3.47e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 201 KRSTITDAGLEvMLEQM--QGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAy 278
Cdd:cd09293   10 KLGQITQSNIS-QLLRIlhSGLEWLELYMCPISDPPLDQLSNCNKLKKLILPGSKLIDDEGLIALAQSCPNLQVLDLRA- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 279 hvtdtalayftarqghsthtlrllsCWEITNHGVVNVVHSLPNLTALSLS---GCSKVTDDGVELVAENLRKLRSLDLSW 355
Cdd:cd09293   88 -------------------------CENITDSGIVALATNCPKLQTINLGrhrNGHLITDVSLSALGKNCTFLQTVGFAG 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116242480 356 CpRITDMAL-EYVACDLHRLEELVLDRCVRITDTGLSYLSTMSS---LRSLYLRWCCQVQDF 413
Cdd:cd09293  143 C-DVTDKGVwELASGCSKSLERLSLNNCRNLTDQSIPAILASNYfpnLSVLEFRGCPLITDF 203
AMN1 cd09293
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ...
 204-356 1.93e-10

Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.


Pssm-ID: 187754 [Multi-domain]  Cd Length: 226  Bit Score: 60.80  E-value: 1.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 204 TITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWS-SLSAR-ITSLSVSD---CINVADDAIAAISQLLPNLAELSLQAY 278
Cdd:cd09293   64 LIDDEGLIALAQSCPNLQVLDLRACENITDSGIVAlATNCPkLQTINLGRhrnGHLITDVSLSALGKNCTFLQTVGFAGC 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 279 HVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL--PNLTALSLSGCSKVTDDGVElVAENLRKLR---SLDL 353
Cdd:cd09293  144 DVTDKGVWELASGCSKSLERLSLNNCRNLTDQSIPAILASNyfPNLSVLEFRGCPLITDFSRI-ILFKLWQPRlnkPILV 222


                 ...
gi 116242480 354 SWC 356
Cdd:cd09293  223 EWC 225
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 205-355 2.43e-07

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 52.87  E-value: 2.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 205 ITDAGLEVMLEQMQG---VVRLELSGcNDFTEAG---LWSSLSAR--ITSLSVSDcINVADDAIAAISQLLPN---LAEL 273
Cdd:COG5238  248 IGDEGVIALAEALKNnttVETLYLSG-NQIGAEGaiaLAKALQGNttLTSLDLSV-NRIGDEGAIALAEGLQGnktLHTL 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 274 SLQAYHVTDT-ALAYFTARQGHST-HTLRLLSCwEITNHGVVNVVHSL---PNLTALSLSGcSKVTDDGVELVAENLR-- 346
Cdd:COG5238  326 NLAYNGIGAQgAIALAKALQENTTlHSLDLSDN-QIGDEGAIALAKYLegnTTLRELNLGK-NNIGKQGAEALIDALQtn 403


                 ....*....
gi 116242480 347 KLRSLDLSW 355
Cdd:COG5238  404 RLHTLILDG 412
AMN1 cd09293
Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in ...
 263-458 2.50e-07

Antagonist of mitotic exit network protein 1; Amn1 has been functionally characterized in Saccharomyces cerevisiae as a component of the Antagonist of MEN pathway (AMEN). The AMEN network is activated by MEN (mitotic exit network) via an active Cdc14, and in turn switches off MEN. Amn1 constitutes one of the alternative mechanisms by which MEN may be disrupted. Specifically, Amn1 binds Tem1 (Termination of M-phase, a GTPase that belongs to the RAS superfamily), and disrupts its association with Cdc15, the primary downstream target. Amn1 is a leucine-rich repeat (LRR) protein, with 12 repeats in the S. cerevisiae ortholog. As a negative regulator of the signal transduction pathway MEN, overexpression of AMN1 slows the growth of wild type cells. The function of the vertebrate members of this family has not been determined experimentally, they have fewer LRRs that determine the extent of this model.


Pssm-ID: 187754 [Multi-domain]  Cd Length: 226  Bit Score: 51.56  E-value: 2.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 263 ISQLL----PNLAELSLQAYHVTDTALAYFTArqGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGV 338
Cdd:cd09293   19 ISQLLrilhSGLEWLELYMCPISDPPLDQLSN--CNKLKKLILPGSKLIDDEGLIALAQSCPNLQVLDLRACENITDSGI 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 339 ELVAENLRKLRSLDLSW---CPRITDMALEYVACDLHRLEELVLDRCvRITDtglsylstmSSLRSLYLRWCCQVQDFGL 415
Cdd:cd09293   97 VALATNCPKLQTINLGRhrnGHLITDVSLSALGKNCTFLQTVGFAGC-DVTD---------KGVWELASGCSKSLERLSL 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 116242480 416 khllalgslrllslAGCPLLTTTGLSGLVqlqeleelELTNCP 458
Cdd:cd09293  167 --------------NNCRNLTDQSIPAIL--------ASNYFP 187
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 178-354 1.83e-06

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 50.17  E-value: 1.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 178 DLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGvvrlelsgcndfteaglwsslSARITSLSVSDcINVAD 257
Cdd:COG5238  193 GDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKG---------------------NKSLTTLDLSN-NQIGD 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 258 DAIAAISQLLPN---LAELSLQAYHVTDTALAYF-TARQGHSTHTLRLLSCWEITNHGVVNVVHSLPN---LTALSLSGC 330
Cdd:COG5238  251 EGVIALAEALKNnttVETLYLSGNQIGAEGAIALaKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGnktLHTLNLAYN 330

                        170       180
                 ....*....|....*....|....*..
gi 116242480 331 sKVTDDGVELVAENL---RKLRSLDLS 354
Cdd:COG5238  331 -GIGAQGAIALAKALqenTTLHSLDLS 356
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
242-420 2.98e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 49.55  E-value: 2.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 242 ARITSLSVSDCINVADdaiaaisqlLPNLAELSLQAYHVTD--TALAYFTArqghsthtLRLLSCWE--ITNhgVVNVVH 317
Cdd:COG4886   96 TNLTELDLSGNEELSN---------LTNLESLDLSGNQLTDlpEELANLTN--------LKELDLSNnqLTD--LPEPLG 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116242480 318 SLPNLTALSLSGCsKVTDDGVELvaENLRKLRSLDLSWCpRITDmaLEYVACDLHRLEELVLDRCvRITDTGLSyLSTMS 397
Cdd:COG4886  157 NLTNLKSLDLSNN-QLTDLPEEL--GNLTNLKELDLSNN-QITD--LPEPLGNLTNLEELDLSGN-QLTDLPEP-LANLT 228

                        170       180
                 ....*....|....*....|....*..
gi 116242480 398 SLRSLYLRWCcQVQDF----GLKHLLA 420
Cdd:COG4886  229 NLETLDLSNN-QLTDLpelgNLTNLEE 254
F-box_FBXO33 cd22104
F-box domain found in F-box only protein 33 (FBXO33) and similar proteins; FBXO33, also called ...
 100-138 4.01e-03

F-box domain found in F-box only protein 33 (FBXO33) and similar proteins; FBXO33, also called FBX33, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It exerts similar functions as F-box involved in polyQ pathogenesis (FipoQ) in modulating the ubiquitination and solubility of expanded SCA3-polyQ proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438876  Cd Length: 48  Bit Score: 35.31  E-value: 4.01e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 116242480 100 KILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLT 138
Cdd:cd22104    7 VVLVHIFSYLPPRDRLRASSTCRRWREALFHPSLWRSLR 45
LRR_CC smart00367
Leucine-rich repeat - CC (cysteine-containing) subfamily;
347-368 4.96e-03

Leucine-rich repeat - CC (cysteine-containing) subfamily;


Pssm-ID: 197685 [Multi-domain]  Cd Length: 26  Bit Score: 34.30  E-value: 4.96e-03
                           10        20
                   ....*....|....*....|..
gi 116242480   347 KLRSLDLSWCPRITDMALEYVA 368
Cdd:smart00367   3 NLRELDLSGCTNITDEGLQALA 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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