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Conserved domains on  [gi|116241329|sp|Q86SQ9|]
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RecName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS; AltName: Full=Cis-isoprenyltransferase; Short=CIT; Short=Cis-IPTase; AltName: Full=Cis-prenyltransferase subunit hCIT; AltName: Full=Epididymis tissue protein Li 189m

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10087541)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates

CATH:  3.40.1180.10
EC:  2.5.1.-
Gene Ontology:  GO:0004659|GO:0016094
PubMed:  16900467|12636086|12135472
SCOP:  4003318

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-248 4.95e-122

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


:

Pssm-ID: 259850  Cd Length: 219  Bit Score: 349.36  E-value: 4.95e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 108 kekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESL 187
Cdd:cd00475   81 ---LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEEL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116241329 188 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:cd00475  158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-248 4.95e-122

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 349.36  E-value: 4.95e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 108 kekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESL 187
Cdd:cd00475   81 ---LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEEL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116241329 188 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:cd00475  158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 32-251 2.43e-110

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 320.08  E-value: 2.43e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329   32 IMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFsrLMEEKEKL 111
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEY--LRRELPEL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  112 QKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAwgVEQGLLDPSDISESLLDKC 191
Cdd:pfam01255  79 HKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIV--KEGKKLDPEDIDEELISSH 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  192 LYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNH 251
Cdd:pfam01255 157 LYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRE 216
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
20-248 4.28e-103

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 302.75  E-value: 4.28e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 100 KfsrLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLD 179
Cdd:COG0020   90 Y---LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116241329 180 PSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:COG0020  167 PEDIDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQ 235
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 27-252 1.19e-89

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 267.73  E-value: 1.19e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329   27 KHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRlme 106
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDR--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  107 EKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISES 186
Cdd:TIGR00055  78 EVKELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116241329  187 LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHS 252
Cdd:TIGR00055 158 TLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHR 223
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 25-248 3.55e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 226.37  E-value: 3.55e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSR- 103
Cdd:PRK14831  20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTL----FERv 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 104 LMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDI 183
Cdd:PRK14831  96 LRRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEI 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116241329 184 SESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14831 176 DENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQ 240
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-248 4.95e-122

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 349.36  E-value: 4.95e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 108 kekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESL 187
Cdd:cd00475   81 ---LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEEL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116241329 188 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:cd00475  158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 32-251 2.43e-110

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 320.08  E-value: 2.43e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329   32 IMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFsrLMEEKEKL 111
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEY--LRRELPEL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  112 QKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAwgVEQGLLDPSDISESLLDKC 191
Cdd:pfam01255  79 HKNGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIV--KEGKKLDPEDIDEELISSH 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  192 LYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNH 251
Cdd:pfam01255 157 LYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRE 216
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
20-248 4.28e-103

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 302.75  E-value: 4.28e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 100 KfsrLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLD 179
Cdd:COG0020   90 Y---LRRELDELHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGELD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116241329 180 PSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:COG0020  167 PEDIDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQ 235
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 27-252 1.19e-89

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 267.73  E-value: 1.19e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329   27 KHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRlme 106
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDR--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  107 EKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISES 186
Cdd:TIGR00055  78 EVKELHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116241329  187 LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHS 252
Cdd:TIGR00055 158 TLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHR 223
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 25-248 3.55e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 226.37  E-value: 3.55e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSR- 103
Cdd:PRK14831  20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTL----FERv 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 104 LMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDI 183
Cdd:PRK14831  96 LRRELEELMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEI 175

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116241329 184 SESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14831 176 DENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQ 240
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 20-248 6.34e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 225.91  E-value: 6.34e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14830  17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 100 KFSRLMEEkekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLD 179
Cdd:PRK14830  97 FLDKFVPE---LIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLN 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116241329 180 PSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14830 174 PEDITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQ 242
PRK14834 PRK14834
isoprenyl transferase;
26-247 3.60e-63

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 200.75  E-value: 3.60e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  26 PKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLM 105
Cdd:PRK14834  15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLFIRRDL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 106 EEkekLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISE 185
Cdd:PRK14834  95 AE---LHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPASIDA 171

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116241329 186 SLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 247
Cdd:PRK14834 172 ETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEY 233
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 25-249 1.01e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 197.53  E-value: 1.01e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSRL 104
Cdd:PRK14832  18 IPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLL----FERL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 105 M-EEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDI 183
Cdd:PRK14832  94 LrRELAQMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAV 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116241329 184 SESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQM 249
Cdd:PRK14832 174 NEQLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQK 239
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 19-273 5.09e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 195.29  E-value: 5.09e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  19 IIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAR 98
Cdd:PRK14836   8 IPANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  99 QKfsrLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLL 178
Cdd:PRK14836  88 KA---LDREVDKLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 179 DPSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYtfwnlfeailqfqmNHSVLQKAR 258
Cdd:PRK14836 165 APDEIDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDF--------------DAQELQQAL 230

                        250       260
                 ....*....|....*....|
gi 116241329 259 DMYAEERKR-----QQLERD 273
Cdd:PRK14836 231 EDYASRERRfgktsAQIADR 250
PRK14835 PRK14835
isoprenyl transferase;
11-248 1.28e-55

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 182.35  E-value: 1.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  11 LWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEV 90
Cdd:PRK14835  27 GYEQRLEREVKHGKLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEV 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  91 DGLMDLARQKfSRLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMA 170
Cdd:PRK14835 107 ETLMNLFERE-ARRMAVDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 171 WGVEQGLLDPSDISESL----LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQ 246
Cdd:PRK14835 186 LEAAATGKSPEEVAAELtpehISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRD 265


                 ..
gi 116241329 247 FQ 248
Cdd:PRK14835 266 YQ 267
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 24-248 1.85e-52

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 173.49  E-value: 1.85e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  24 PMPKHIAFIMDGNRRYAKK----CQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL--- 96
Cdd:PRK14840  17 SLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLfns 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  97 -ARQKFSRLMEEKeklqkhgVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQ 175
Cdd:PRK14840  97 qLDSQLPYLHENE-------IRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLAN 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 116241329 176 GLLDPSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14840 170 KKISSDDISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQ 242
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
25-247 1.06e-50

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 168.07  E-value: 1.06e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQkfsRL 104
Cdd:PRK14833   4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKK---YL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 105 MEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREM--AWGVEQGLLdpsD 182
Cdd:PRK14833  81 KDERSTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLleSPPSHIGEL---E 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116241329 183 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 247
Cdd:PRK14833 158 SLEEEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDF 222
PRK14838 PRK14838
isoprenyl transferase;
25-248 3.23e-50

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 167.36  E-value: 3.23e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFsrl 104
Cdd:PRK14838  10 IPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLDSI--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 105 meEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDIS 184
Cdd:PRK14838  87 --EEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNPEEIT 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116241329 185 ESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14838 165 EESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQ 228
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 20-247 1.45e-47

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 160.33  E-value: 1.45e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14829   9 IPKNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 100 KFSRlmeEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLD 179
Cdd:PRK14829  89 VIHR---RREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKIS 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 116241329 180 PSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 247
Cdd:PRK14829 166 GDRVTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEY 233
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 11-251 1.57e-46

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 158.37  E-value: 1.57e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  11 LWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVER-QEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSE 89
Cdd:PRK14828  12 VYARRLLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  90 VDGLMDLARQKFSRLMEEKEKLQKHgvcirvLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREM 169
Cdd:PRK14828  92 LNPLLDIIEDVVRQLAPDGRWRVRH------VGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 170 AW-GVEQGLlDPSDISES----LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAI 244
Cdd:PRK14828 166 LTeHKDKGT-SIDELAESvtvdAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRAL 244


                 ....*..
gi 116241329 245 LQFQMNH 251
Cdd:PRK14828 245 RDYSQRE 251
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 25-244 1.76e-46

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 157.46  E-value: 1.76e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRl 104
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDR- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 105 meEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGllDPSDIS 184
Cdd:PRK14841  82 --EMELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQG--KKIELT 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 185 ESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAI 244
Cdd:PRK14841 158 EETFRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAI 217
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 20-243 2.21e-45

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 156.27  E-value: 2.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14827  62 IPADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRD 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 100 KFSRlmeEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLD 179
Cdd:PRK14827 142 VVRR---RRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLN 218

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116241329 180 PSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEA 243
Cdd:PRK14827 219 PERITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAA 282
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
33-258 1.51e-41

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 144.36  E-value: 1.51e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  33 MDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLarqkFSRLME-EKEKL 111
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMEL----FVWALDsEVKSL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 112 QKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDKC 191
Cdd:PRK10240  77 HRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQH 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116241329 192 LYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTfWNLFEAILqfqmnHSVLQKAR 258
Cdd:PRK10240 157 ICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFD-EQDFEGAL-----NAFANRER 217
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 23-235 6.84e-40

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 139.96  E-value: 6.84e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  23 GPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARqkfS 102
Cdd:PRK14837   4 NSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIA---D 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 103 RLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMawgVEQGlLDPSD 182
Cdd:PRK14837  81 YLSSEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKF---LSSG-LDLET 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 116241329 183 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEY 235
Cdd:PRK14837 157 LNENVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEY 209
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 25-248 8.91e-39

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 137.43  E-value: 8.91e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVdglmdlaRQKFSRL 104
Cdd:PRK14842   8 IPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEI-------RSIFGLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 105 ME----EKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEI-SNAVREMAWGVEQGLLD 179
Cdd:PRK14842  81 VEfietRLDTIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELlRAAQEVFLARKAKKVTL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116241329 180 PSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14842 161 EKPLKEKEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYE 229
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
28-248 1.43e-37

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 134.11  E-value: 1.43e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARqkfSRLMEE 107
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLR---AYLRNE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 108 KEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMawgveqglLDPSDISESL 187
Cdd:PRK14839  89 TERLARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAAKA--------LGPEGLSREA 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116241329 188 LDKCLyTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 248
Cdd:PRK14839 161 FSDLL-TGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFH 220
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 9-249 4.13e-29

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 113.94  E-value: 4.13e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329   9 LSLWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKS 88
Cdd:PTZ00349   3 LNIIERFITSLLRDFINIKHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329  89 EVD-----GLMDLARQKFSRLMEEKEKLQkhgvcIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEIS 163
Cdd:PTZ00349  83 EIHflfylNLLILINEDFFFKFIKDNKIK-----IKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMS 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116241329 164 --------------NAVRE---------MAWGVEQGLLDPSDISESL-------------LD-----KC----------- 191
Cdd:PTZ00349 158 lckfnpnlyfdtykNLLEEkkilcgsniLTDPIKEGTFAIPDDEDECdyldheleneridLDlkfdgDCicgeksflnee 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116241329 192 ----------LYTNRSPHPDILIRTSGEVRLSDFLLWQTSH-SCLVFQPVLWPEYTFWNLFEAILQFQM 249
Cdd:PTZ00349 238 qieivnyhkkLLTSDLPPPNILIRTSGEKRLSDFMLYQISEfTEIYFINEYWPIFNFLQFIYIILHYTI 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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