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Conserved domains on  [gi|1162406145|gb|OPX20845|]
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MAG: hypothetical protein BZ151_01870 [Desulfobacca sp. 4484_104]

Protein Classification

GspE/PulE family protein( domain architecture ID 11457962)

GspE/PulE family protein similar to type II secretion system protein E, an essential component of type II systems, and to type IV pilus assembly ATPase PilB

CATH:  3.40.50.300
PubMed:  11226268
SCOP:  4005829|4004682

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
2-503 0e+00

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 681.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145   2 LDAADFPETPPALTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFEA 81
Cdd:COG2804    66 VDLDELEIDPEVLELLPEELARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVEPVVATESDIERALDRLYGS 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  82 EVDMAANEGSAGGELDFEDqlwDSPEHLKDMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMES 161
Cdd:COG2804   146 ESSIEELLEELAEDLTSEE---EDLEDLLEEADDAPVVRLVNAILEDAIKEGASDIHIEPYEKRLRVRFRIDGVLREVLR 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 162 INIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIR 241
Cdd:COG2804   223 LPKSLAPALVSRIKIMANLDIAERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLRILDKSAALLDLEQLGFSPDQL 302
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 242 RQFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQD 321
Cdd:COG2804   303 ERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQVQVNPKIGLTFASALRSILRQD 382
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 322 PDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCSATVEL 401
Cdd:COG2804   383 PDVIMVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEP 462
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 402 TDGEREQLALELQIPVSrvlPTYQRGRGCKTCGDTGYRGRIGIYEYLLLDEKVRRAISRGDNlESTLRRSREDGGIPTLR 481
Cdd:COG2804   463 DPEELERLGLPPEELAP---LTFYRGVGCEHCNGTGYKGRTGIYELLVIDDELRELIAEGAS-AAELREAARKEGMRTLR 538
                         490       500
                  ....*....|....*....|..
gi 1162406145 482 DDGIDKVAQGITTYEEILRVTR 503
Cdd:COG2804   539 EDGLEKVLQGITTLEEVLRVTG 560
 
Name Accession Description Interval E-value
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
2-503 0e+00

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 681.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145   2 LDAADFPETPPALTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFEA 81
Cdd:COG2804    66 VDLDELEIDPEVLELLPEELARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVEPVVATESDIERALDRLYGS 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  82 EVDMAANEGSAGGELDFEDqlwDSPEHLKDMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMES 161
Cdd:COG2804   146 ESSIEELLEELAEDLTSEE---EDLEDLLEEADDAPVVRLVNAILEDAIKEGASDIHIEPYEKRLRVRFRIDGVLREVLR 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 162 INIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIR 241
Cdd:COG2804   223 LPKSLAPALVSRIKIMANLDIAERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLRILDKSAALLDLEQLGFSPDQL 302
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 242 RQFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQD 321
Cdd:COG2804   303 ERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQVQVNPKIGLTFASALRSILRQD 382
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 322 PDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCSATVEL 401
Cdd:COG2804   383 PDVIMVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEP 462
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 402 TDGEREQLALELQIPVSrvlPTYQRGRGCKTCGDTGYRGRIGIYEYLLLDEKVRRAISRGDNlESTLRRSREDGGIPTLR 481
Cdd:COG2804   463 DPEELERLGLPPEELAP---LTFYRGVGCEHCNGTGYKGRTGIYELLVIDDELRELIAEGAS-AAELREAARKEGMRTLR 538
                         490       500
                  ....*....|....*....|..
gi 1162406145 482 DDGIDKVAQGITTYEEILRVTR 503
Cdd:COG2804   539 EDGLEKVLQGITTLEEVLRVTG 560
type_II_gspE TIGR02533
type II secretion system protein E; This family describes GspE, the E protein of the type II ...
14-502 0e+00

type II secretion system protein E; This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 131585 [Multi-domain]  Cd Length: 486  Bit Score: 555.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  14 LTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFEAEVDMAANE-GSA 92
Cdd:TIGR02533   1 VRRLPIGFAKQSRVLPLSEHDGTLVVAVSDPLDLAALDEVRRLFGAPVQLIIATASEIDDAINSVYARTGSAAAQIvEEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  93 GGELDFEDQLWDSP--EHLKDMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAI 170
Cdd:TIGR02533  81 EGEDDLSALELDEPkiEDLLDLEDDAPVIRLVNSLLSRAVKERASDIHIEPFEKALVVRFRVDGVLRDVLSPPKKLHAAL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 171 ISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIRRQFEQAIKL 250
Cdd:TIGR02533 161 VSRVKIMAKLNIAEKRLPQDGRISLRVGGRDIDIRVSTVPTSHGERVVMRLLDKTAVRLDLETLGMSPELLSRFERLIRR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 251 PYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEI 330
Cdd:TIGR02533 241 PHGIILVTGPTGSGKTTTLYAALSRLNTPERNILTVEDPVEYQIEGIGQIQVNPKIGLTFAAGLRAILRQDPDIIMVGEI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 331 RDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCSATVELTDGEREQLA 410
Cdd:TIGR02533 321 RDLETAQIAIQASLTGHLVLSTLHTNDAAGAVTRLIDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEATPEEIALFG 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 411 LELQIPVsrvlpTYQRGRGCKTCGDTGYRGRIGIYEYLLLDEKVRRAISRGDNlESTLRRSREDGGIPTLRDDGIDKVAQ 490
Cdd:TIGR02533 401 ISPEGPI-----NLYRPVGCPHCNHTGYLGRTGIYELLIVDDDLRSLIHSRAD-EGEIKEIARAAGMRTLRDDGLRKVLA 474
                         490
                  ....*....|..
gi 1162406145 491 GITTYEEILRVT 502
Cdd:TIGR02533 475 GITTIEEVLRVT 486
PRK10436 PRK10436
hypothetical protein; Provisional
111-502 1.15e-139

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 410.09  E-value: 1.15e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 111 DMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQD 190
Cdd:PRK10436   77 DQEKDTPVAQLINQTLQSALQKRASDIHFEPAQNHYRIRLRIDGVLHPLPDPSPELGAALTARLKVLGNLDIAERRLPQD 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 191 GRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLY 270
Cdd:PRK10436  157 GQFTVELAGNAYSFRIATLPCRGGEKVVLRLLQQVQQALDLETLGMTPAQLAQFRQALQQPQGLILVTGPTGSGKTVTLY 236
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 271 AALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVF 350
Cdd:PRK10436  237 SALQTLNTAQINICSVEDPVEIPLAGINQTQIHPKAGLTFQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVL 316
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 351 STLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCsatveltdgeREQLALELQIPVS---RVLPTYQrG 427
Cdd:PRK10436  317 STLHTNSTSETLVRLQQMGIARWMLASALKLVIAQRLVRKLCPHC----------RQQASEPIHLPPNiwpGPLPHWQ-A 385
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1162406145 428 RGCKTCGdTGYRGRIGIYEYLLLDEKVRRAISRG---DNLESTLRRSredgGIPTLRDDGIDKVAQGITTYEEILRVT 502
Cdd:PRK10436  386 VGCEHCY-HGYYGRTALFEVLPITPVLQQAIASNaspEELETHARQQ----GMTTLFENGLLAVEQGLTTLEELYRVL 458
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
123-390 2.94e-115

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 340.80  E-value: 2.94e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 123 NHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDI 202
Cdd:pfam00437   1 NLIPLEALDEGASDIHVEPPERIVWIRFRVDGVLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPLRIGGKGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 203 DIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVK 282
Cdd:pfam00437  81 RVRVSTLPTAGGEKLVIRLLDPSNVALSLDELGMTGAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELNTRDEN 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 283 IVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAI 362
Cdd:pfam00437 161 IVTVEDPVEIQLEGINQVQLNARAGVTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSAAGAL 240
                         250       260
                  ....*....|....*....|....*...
gi 1162406145 363 TRLEDMGVERFMVASAVVAVLAQRLVRR 390
Cdd:pfam00437 241 TRLQDMGVPPFELASSLLLVIAQRLVRK 268
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
123-372 1.79e-93

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 284.73  E-value: 1.79e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 123 NHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDI 202
Cdd:NF041000    1 EELIEEAIELRASDIHFLPREDGYQIKFRIGGGLIPYRELSLEEGQRLISYFKFLAGMDIGEKRRPQSGAFTYELNEQQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 203 DIRVSSIPAFFG-ESLVLRLLKQDEINLDLDslgFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLY--AALNTLNQp 279
Cdd:NF041000   81 SLRLSTVGDFLGrESLVIRLLYQLEQIKPQL---FFPEQFQLLKQLLQRRSGLILFSGPTGSGKTTTMYslARKLALNK- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 280 dvKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSL 359
Cdd:NF041000  157 --QVITIEDPVEIKEPNFLQLQVNEKAGMTYDTLLKAALRHRPDILIIGEIRDAETAKAAIRAALTGHLVLSTVHAKSAA 234
                         250
                  ....*....|...
gi 1162406145 360 GAITRLEDMGVER 372
Cdd:NF041000  235 GVIYRLLELGISK 247
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
243-391 1.67e-83

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 255.10  E-value: 1.67e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 243 QFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDP 322
Cdd:cd01129     2 RLRRLIKRPHGLILVTGPTGSGKTTTLYAMLRELNGPERNIITIEDPVEYQIPGINQSQVNEKIGLTFADALRAILRQDP 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1162406145 323 DIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRV 391
Cdd:cd01129    82 DIIMVGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEPFLLASALRGVIAQRLVGRT 150
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
251-330 6.31e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.43  E-value: 6.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  251 PYGMILVTGPTGSGKTTTLYAALNTLNQP--DVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFS----NLLRSFLRQ-DPD 323
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPggGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGelrlRLALALARKlKPD 80

                   ....*..
gi 1162406145  324 IMLVGEI 330
Cdd:smart00382  81 VLILDEI 87
 
Name Accession Description Interval E-value
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
2-503 0e+00

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 681.92  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145   2 LDAADFPETPPALTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFEA 81
Cdd:COG2804    66 VDLDELEIDPEVLELLPEELARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVEPVVATESDIERALDRLYGS 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  82 EVDMAANEGSAGGELDFEDqlwDSPEHLKDMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMES 161
Cdd:COG2804   146 ESSIEELLEELAEDLTSEE---EDLEDLLEEADDAPVVRLVNAILEDAIKEGASDIHIEPYEKRLRVRFRIDGVLREVLR 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 162 INIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIR 241
Cdd:COG2804   223 LPKSLAPALVSRIKIMANLDIAERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLRILDKSAALLDLEQLGFSPDQL 302
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 242 RQFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQD 321
Cdd:COG2804   303 ERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQVQVNPKIGLTFASALRSILRQD 382
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 322 PDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCSATVEL 401
Cdd:COG2804   383 PDVIMVGEIRDLETAEIAVQAALTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEP 462
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 402 TDGEREQLALELQIPVSrvlPTYQRGRGCKTCGDTGYRGRIGIYEYLLLDEKVRRAISRGDNlESTLRRSREDGGIPTLR 481
Cdd:COG2804   463 DPEELERLGLPPEELAP---LTFYRGVGCEHCNGTGYKGRTGIYELLVIDDELRELIAEGAS-AAELREAARKEGMRTLR 538
                         490       500
                  ....*....|....*....|..
gi 1162406145 482 DDGIDKVAQGITTYEEILRVTR 503
Cdd:COG2804   539 EDGLEKVLQGITTLEEVLRVTG 560
type_II_gspE TIGR02533
type II secretion system protein E; This family describes GspE, the E protein of the type II ...
14-502 0e+00

type II secretion system protein E; This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 131585 [Multi-domain]  Cd Length: 486  Bit Score: 555.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  14 LTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFEAEVDMAANE-GSA 92
Cdd:TIGR02533   1 VRRLPIGFAKQSRVLPLSEHDGTLVVAVSDPLDLAALDEVRRLFGAPVQLIIATASEIDDAINSVYARTGSAAAQIvEEI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  93 GGELDFEDQLWDSP--EHLKDMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAI 170
Cdd:TIGR02533  81 EGEDDLSALELDEPkiEDLLDLEDDAPVIRLVNSLLSRAVKERASDIHIEPFEKALVVRFRVDGVLRDVLSPPKKLHAAL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 171 ISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIRRQFEQAIKL 250
Cdd:TIGR02533 161 VSRVKIMAKLNIAEKRLPQDGRISLRVGGRDIDIRVSTVPTSHGERVVMRLLDKTAVRLDLETLGMSPELLSRFERLIRR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 251 PYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEI 330
Cdd:TIGR02533 241 PHGIILVTGPTGSGKTTTLYAALSRLNTPERNILTVEDPVEYQIEGIGQIQVNPKIGLTFAAGLRAILRQDPDIIMVGEI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 331 RDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCSATVELTDGEREQLA 410
Cdd:TIGR02533 321 RDLETAQIAIQASLTGHLVLSTLHTNDAAGAVTRLIDMGVEPFLLASSLLGVLAQRLVRRLCPHCKEPYEATPEEIALFG 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 411 LELQIPVsrvlpTYQRGRGCKTCGDTGYRGRIGIYEYLLLDEKVRRAISRGDNlESTLRRSREDGGIPTLRDDGIDKVAQ 490
Cdd:TIGR02533 401 ISPEGPI-----NLYRPVGCPHCNHTGYLGRTGIYELLIVDDDLRSLIHSRAD-EGEIKEIARAAGMRTLRDDGLRKVLA 474
                         490
                  ....*....|..
gi 1162406145 491 GITTYEEILRVT 502
Cdd:TIGR02533 475 GITTIEEVLRVT 486
type_IV_pilB TIGR02538
type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus ...
1-503 4.10e-167

type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274186 [Multi-domain]  Cd Length: 564  Bit Score: 484.13  E-value: 4.10e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145   1 MLDAADFPETPPALTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFE 80
Cdd:TIGR02538  58 LLDLNAFDPDALPVQLVSEELIQKHQALPLFKRGNTLFVAVSDPTNISALDDIRFATGLNVEVVIVEEDKLSALIEKYYG 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  81 AEVDMAANEG----SAGGELDFEDQLWDSP--EHLKDMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDG 154
Cdd:TIGR02538 138 GSDSLAKELGdediGDLEELDVDAIDDEGPddIEQDAVDDDAPIVKFVNKILLDAIRKGASDIHFEPYEKSYRVRFRIDG 217
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 155 VLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFA-GGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDS 233
Cdd:TIGR02538 218 ILHEVAQPPLALANRIAARIKVMSRLDIAEKRIPQDGRIKLKlSKSKAIDFRVSTLPTLFGEKVVLRILDSSAAQLDIDK 297
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 234 LGFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNL 313
Cdd:TIGR02538 298 LGFEPDQKALFLEAIHKPQGMVLVTGPTGSGKTVSLYTALNILNTEEVNISTAEDPVEINLPGINQVNVNPKIGLTFAAA 377
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 314 LRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCP 393
Cdd:TIGR02538 378 LRSFLRQDPDIIMVGEIRDLETAEIAIKAAQTGHLVLSTLHTNDAPETLARLVNMGIAPFNIASSVNLIMAQRLARRLCS 457
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 394 DCSATVELTdgerEQLALELQIPVSRvLPTYQ--RGRGCKTCGDTGYRGRIGIYEYLLLDEKVRRAISRGDNLESTLRRS 471
Cdd:TIGR02538 458 HCKAPEEVP----AEALLELGFTQED-LADLKlyGPVGCDECSNTGYKGRVGIYEVMPMSEEIAELILKGGNALQIAELA 532
                         490       500       510
                  ....*....|....*....|....*....|..
gi 1162406145 472 REDgGIPTLRDDGIDKVAQGITTYEEILRVTR 503
Cdd:TIGR02538 533 QKE-GMRTLRRSGLLKVKQGVTSLEEVLRVTV 563
PRK10436 PRK10436
hypothetical protein; Provisional
111-502 1.15e-139

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 410.09  E-value: 1.15e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 111 DMASEAPIIRLVNHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQD 190
Cdd:PRK10436   77 DQEKDTPVAQLINQTLQSALQKRASDIHFEPAQNHYRIRLRIDGVLHPLPDPSPELGAALTARLKVLGNLDIAERRLPQD 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 191 GRIRFAGGGHDIDIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLY 270
Cdd:PRK10436  157 GQFTVELAGNAYSFRIATLPCRGGEKVVLRLLQQVQQALDLETLGMTPAQLAQFRQALQQPQGLILVTGPTGSGKTVTLY 236
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 271 AALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVF 350
Cdd:PRK10436  237 SALQTLNTAQINICSVEDPVEIPLAGINQTQIHPKAGLTFQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVL 316
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 351 STLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRVCPDCsatveltdgeREQLALELQIPVS---RVLPTYQrG 427
Cdd:PRK10436  317 STLHTNSTSETLVRLQQMGIARWMLASALKLVIAQRLVRKLCPHC----------RQQASEPIHLPPNiwpGPLPHWQ-A 385
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1162406145 428 RGCKTCGdTGYRGRIGIYEYLLLDEKVRRAISRG---DNLESTLRRSredgGIPTLRDDGIDKVAQGITTYEEILRVT 502
Cdd:PRK10436  386 VGCEHCY-HGYYGRTALFEVLPITPVLQQAIASNaspEELETHARQQ----GMTTLFENGLLAVEQGLTTLEELYRVL 458
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
123-390 2.94e-115

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 340.80  E-value: 2.94e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 123 NHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDI 202
Cdd:pfam00437   1 NLIPLEALDEGASDIHVEPPERIVWIRFRVDGVLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPLRIGGKGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 203 DIRVSSIPAFFGESLVLRLLKQDEINLDLDSLGFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVK 282
Cdd:pfam00437  81 RVRVSTLPTAGGEKLVIRLLDPSNVALSLDELGMTGAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELNTRDEN 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 283 IVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAI 362
Cdd:pfam00437 161 IVTVEDPVEIQLEGINQVQLNARAGVTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSAAGAL 240
                         250       260
                  ....*....|....*....|....*...
gi 1162406145 363 TRLEDMGVERFMVASAVVAVLAQRLVRR 390
Cdd:pfam00437 241 TRLQDMGVPPFELASSLLLVIAQRLVRK 268
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
123-372 1.79e-93

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 284.73  E-value: 1.79e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 123 NHLISRAVSLNASDIHIEPRKSHVQIRYRIDGVLHNMESINIKLKSAIISRVKLIAKMDIAEMRLPQDGRIRFAGGGHDI 202
Cdd:NF041000    1 EELIEEAIELRASDIHFLPREDGYQIKFRIGGGLIPYRELSLEEGQRLISYFKFLAGMDIGEKRRPQSGAFTYELNEQQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 203 DIRVSSIPAFFG-ESLVLRLLKQDEINLDLDslgFPDTIRRQFEQAIKLPYGMILVTGPTGSGKTTTLY--AALNTLNQp 279
Cdd:NF041000   81 SLRLSTVGDFLGrESLVIRLLYQLEQIKPQL---FFPEQFQLLKQLLQRRSGLILFSGPTGSGKTTTMYslARKLALNK- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 280 dvKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSL 359
Cdd:NF041000  157 --QVITIEDPVEIKEPNFLQLQVNEKAGMTYDTLLKAALRHRPDILIIGEIRDAETAKAAIRAALTGHLVLSTVHAKSAA 234
                         250
                  ....*....|...
gi 1162406145 360 GAITRLEDMGVER 372
Cdd:NF041000  235 GVIYRLLELGISK 247
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
243-391 1.67e-83

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 255.10  E-value: 1.67e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 243 QFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDP 322
Cdd:cd01129     2 RLRRLIKRPHGLILVTGPTGSGKTTTLYAMLRELNGPERNIITIEDPVEYQIPGINQSQVNEKIGLTFADALRAILRQDP 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1162406145 323 DIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMGVERFMVASAVVAVLAQRLVRRV 391
Cdd:cd01129    82 DIIMVGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEPFLLASALRGVIAQRLVGRT 150
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
122-500 8.47e-66

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


Pssm-ID: 442056  Cd Length: 342  Bit Score: 216.11  E-value: 8.47e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 122 VNHLISRAVSLNASDIHIeprKSHVQIRYRIDGVLhnmesinIKLKSAIISRVKLiakMDIAEMRLPQDGRIRFAGGGhD 201
Cdd:COG2805     5 LDELLKLAVEQGASDLHL---TVGSPPMLRIDGEL-------VPLDDPPLTPEDL---EALLKEILTEEQRERLEEEG-E 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 202 ID----------IRVSsipAFF---GESLVLRLLKqDEInLDLDSLGFPDTIRRqfeqAIKLPYGMILVTGPTGSGKTTT 268
Cdd:COG2805    71 LDfsyslpglgrFRVN---IFRqrgGVAAVLRLIP-SEI-PTLEELGLPPVLKE----LAELPRGLVLVTGPTGSGKSTT 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 269 LYAALNTLNQ-PDVKIVTVEDPVEYQLDGVNQVQVQSAIG---LTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSAL 344
Cdd:COG2805   142 LAAMIDYINEtRAKHIITIEDPIEFVHKHKKSLINQREVGrdtPSFANALRAALREDPDVILVGEMRDLETIEAALTAAE 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 345 TGHMVFSTLHTNDSLGAITRLEDM--GVERFMVasavvavlaqrlvrrvcpdcsatveltdgeREQLALELQIPVS-RVL 421
Cdd:COG2805   222 TGHLVFATLHTNSAAQTIDRIIDVfpPEEQAQI------------------------------RSQLAESLRGVISqRLL 271
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 422 PTyqrgrgcktcgdTGYRGRIGIYEYLLLDEKVRRAISRGD--NLESTLRRSREDGGIpTLRDDGIDKVAQGITTYEEIL 499
Cdd:COG2805   272 PR------------ADGGGRVAAREILVNTPAVRNLIREGKthQIPSLIQTGKKLGMQ-TMDQSLAELVKEGLITEETAL 338

                  .
gi 1162406145 500 R 500
Cdd:COG2805   339 A 339
pilT_fam TIGR01420
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ...
125-416 4.98e-48

pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]


Pssm-ID: 273613  Cd Length: 343  Bit Score: 169.04  E-value: 4.98e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 125 LISRAVSLNASDIHIeprKSHVQIRYRIDGVlhnMESINIKLKSAIISRVKLIAKMDIAEMR-LPQDGRIRFAGGGHD-I 202
Cdd:TIGR01420   5 ILREAVKLGASDIHL---TAGAPPAMRIDGD---LVRIEFEPLTPEDTQKLAREILSEKQREeFEENGELDFSFSLPGvG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 203 DIRVSSIPAFFGESLVLRLLKQDEINLDldSLGFPDTirrqFEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQ-PDV 281
Cdd:TIGR01420  79 RFRVNAFYQRGGVALVLRLIPSKIPTFE--ELGLPPV----LRELAERPRGLILVTGPTGSGKSTTLASMIDYINKnKAY 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 282 KIVTVEDPVEYQLDGVNQVQVQSAIG---LTFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDS 358
Cdd:TIGR01420 153 HIITIEDPIEYVHTNKRSLINQREVGedtLSFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTLHTNSA 232
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1162406145 359 LGAITRLEDMGVE------RFMVASAVVAVLAQRLVRRvcpdcsatvelTDGEREQLALELQIP 416
Cdd:TIGR01420 233 AQTIERIIDVFPAeeqeqiRTQLAESLVAIISQRLLPK-----------ADGGGRVLAVEILIN 285
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
229-475 6.55e-47

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 162.32  E-value: 6.55e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 229 LDLDSLGFPDTIrrqfEQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNQP-DVKIVTVEDPVEY----QLDGVNQVQVq 303
Cdd:cd01131     2 PTFEELGLPPVL----KDLALKPRGLVLVTGPTGSGKSTTLAAMIDYINETrSKHIITIEDPIEFvhkhKKSLINQREV- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 304 saiGL---TFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDMgverfmvasavV 380
Cdd:cd01131    77 ---GRdteSFAAALRAALREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIIDV-----------F 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 381 AVLAQRLVrrvcpdcsatveltdgeREQLALELQIPVS-RVLPTYQRGrgcktcgdtgyrGRIGIYEYLLLDEKVRRAIS 459
Cdd:cd01131   143 PPEQQEQV-----------------RIQLASSLRGVISqRLLPKKDGG------------GRVAAFEILINTPAIRNLIR 193
                         250
                  ....*....|....*...
gi 1162406145 460 RG--DNLESTLRRSREDG 475
Cdd:cd01131   194 EGktHQIPSLIQTGARDG 211
type_II_IV_secretion_ATPases cd19477
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ...
244-369 5.98e-32

type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410885 [Multi-domain]  Cd Length: 168  Bit Score: 120.58  E-value: 5.98e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 244 FEQAIKLPyGMILVTGPTGSGKTTTLYAALNTLNQPDvKIVTVEDPVEYQL---DGVNQVQVQSAIglTFSNLLRSFLRQ 320
Cdd:cd19477     3 IKDGIAIG-KNVIVCGGTGSGKTTYIKSILEFIPKEE-RIISIEDTEEIVFkhhKNYTQLFFGGNI--TSADCLKSCLRQ 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1162406145 321 DPDIMLVGEIRDvETADIAIQSALTGH-MVFSTLHTNDSLGAITRLEDMG 369
Cdd:cd19477    79 RPDRIILGELRS-SEAYDFYNVLCSGHkGTLTTLHAGSSEEAFIRLAN*S 127
DotB_TraJ cd19516
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ...
253-372 2.76e-31

dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.


Pssm-ID: 410924 [Multi-domain]  Cd Length: 179  Bit Score: 119.02  E-value: 2.76e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 253 GMILVTGPTGSGKTTTLYAALNTL---NQPDVKIVTVEDPVEYQLDGVNQ---VQVQSAIGLTFSNL---LRSFLRQDPD 323
Cdd:cd19516    12 GLVYVAGATGSGKSTLLAAIYRYIlenDPPDRKIITYEDPIEFVYDGIKSkhsIIVQSQIPRHFKSFakaVREALRRKPS 91
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1162406145 324 IMLVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDM--GVER 372
Cdd:cd19516    92 LIGVGELRDQETISAAVEASLTGHPVYSTVHTKSVAETIRRLISLfpPEER 142
PilU COG5008
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
129-364 2.95e-27

Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];


Pssm-ID: 444032  Cd Length: 370  Bit Score: 112.50  E-value: 2.95e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 129 AVSLNASDIHIeprKSHVQIRYRIDGVLHNMEsiNIKLKSAiisRVKLIAK--MD---IAE--------MRLPQDGRIRF 195
Cdd:COG5008    10 MVEKKASDLFI---TAGAPPSIKIDGKLTPLS--QQPLTPE---QVRELAYsiMNeeqREEfertkecnFAISLPGVGRF 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 196 aggghdidiRVSsipAFF--GE-SLVLRLLKQDeInLDLDSLGFPDTIRrqfeQAIKLPYGMILVTGPTGSGKTTTLyAA 272
Cdd:COG5008    82 ---------RVN---AFRqrGSvGMVLRRIETE-I-PTLDELGLPPVLK----DLIMEKRGLVLFVGATGSGKSTTL-AA 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 273 L----NTlNQPDvKIVTVEDPVEY--QLDG--VNQVQVqsaiGL---TFSNLLRSFLRQDPDIMLVGEIRDVETADIAIQ 341
Cdd:COG5008   143 MidhrNE-NSSG-HILTIEDPIEFvhKHKKsiVTQREV----GVdteSYEVALKNALRQAPDVILIGEIRDRETMEHAIA 216
                         250       260
                  ....*....|....*....|...
gi 1162406145 342 SALTGHMVFSTLHTNDSLGAITR 364
Cdd:COG5008   217 FAETGHLCLATLHANNANQALDR 239
plasmid_TraJ TIGR02525
plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated ...
253-368 1.27e-23

plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated with plasmid transfer loci in bacteria. This family is most similar to the DotB ATPase of a type-IV secretion-like system of obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii (TIGR02524). [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 131577 [Multi-domain]  Cd Length: 372  Bit Score: 102.19  E-value: 1.27e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 253 GMILVTGPTGSGKTTTLYAALNTL--NQPDVKIVTVEDPVEYQLDGVNQV--QVQSAIGL---TFSNLLRSFLRQDPDIM 325
Cdd:TIGR02525 150 GLGLICGETGSGKSTLAASIYQHCgeTYPDRKIVTYEDPIEYILGSPDDLlpPAQSQIGRdvdSFANGIRLALRRAPKII 229
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1162406145 326 LVGEIRDVETADIAIQSALTGHMVFSTLHTNDSLGAITRLEDM 368
Cdd:TIGR02525 230 GVGEIRDLETFQAAVLAGQSGHFCLGTLHVKSPGEAISRCLQM 272
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
255-371 2.03e-23

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 96.84  E-value: 2.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 255 ILVTGPTGSGKTTTLYAALNTLNqPDVKIVTVEDPVEYQLDGVNQVQ------VQSAIGLTFSNLLRSFLRQDPDIMLVG 328
Cdd:cd01130    15 ILISGGTGSGKTTLLNALLSFIP-PDERIVTIEDTRELQLPHPNVVHlltrpgGGEKGEVTMADLLKAALRMRPDRIIVG 93
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1162406145 329 EIRDVETADiAIQSALTGHM-VFSTLHTNDSLGAITRLEDMGVE 371
Cdd:cd01130    94 EVRGGEAYD-MLQAMNTGHPgSITTIHANSAEDAIDRLATLVLE 136
VirB11 COG0630
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ...
252-374 1.46e-21

Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440395 [Multi-domain]  Cd Length: 462  Bit Score: 97.07  E-value: 1.46e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 252 YGM-ILVTGPTGSGKTTTLYAALNTLNqPDVKIVTVEDPVEYQLDGVNQVQV---------QSAIGLTfsNLLRSFLRQD 321
Cdd:COG0630   289 NGKsVLVAGGTASGKTTLLNALLSFIP-PDAKIVTIEDTRELNLPHENWISLvtresfggeEGDVTMF--DLLKAALRQR 365
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1162406145 322 PDIMLVGEIRDVEtADIAIQSALTGHMVFSTLHTNDSLGAITRL--EDMGVERFM 374
Cdd:COG0630   366 PDYIVVGEVRGEE-AYTLFQAMATGHGVLSTFHADSVESAINRLtsPPINVPRTL 419
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
216-369 2.71e-18

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 86.76  E-value: 2.71e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 216 SLVLRLLKQDEINL-DLDSLG-FPDTIRRQFEQAIKLPYGmILVTGPTGSGKTTTLyAALNTLNQPDVKIVTVEDPVEYQ 293
Cdd:COG4962   145 SLSIRKFRKRPLTLeDLVALGsLTPEMAEFLRAAVRARLN-ILVSGGTGSGKTTLL-NALSGFIPPDERIVTIEDAAELQ 222
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 294 LDGVNQVQVQS---------AIGLtfSNLLRSFLRQDPDIMLVGEIRDVETADIaIQSALTGH---MvfSTLHTNDSLGA 361
Cdd:COG4962   223 LQHPHVVRLETrppnvegagEVTL--RDLVRNALRMRPDRIIVGEVRGAEALDM-LQAMNTGHdgsM--STLHANSARDA 297

                  ....*...
gi 1162406145 362 ITRLEDMG 369
Cdd:COG4962   298 LARLETLA 305
PRK13894 PRK13894
conjugal transfer ATPase TrbB; Provisional
255-365 1.49e-15

conjugal transfer ATPase TrbB; Provisional


Pssm-ID: 184377  Cd Length: 319  Bit Score: 77.47  E-value: 1.49e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 255 ILVTGPTGSGKTTTLYAALNTL--NQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRD 332
Cdd:PRK13894  151 ILVIGGTGSGKTTLVNAIINEMviQDPTERVFIIEDTGEIQCAAENYVQYHTSIDVNMTALLKTTLRMRPDRILVGEVRG 230
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1162406145 333 VETADIaIQSALTGHM-VFSTLHTNDSLGAITRL 365
Cdd:PRK13894  231 PEALDL-LMAWNTGHEgGAATLHANNAKAGLDRL 263
VirB11 TIGR02788
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ...
255-368 7.81e-13

P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.


Pssm-ID: 274301  Cd Length: 308  Bit Score: 69.30  E-value: 7.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 255 ILVTGPTGSGKTTTLYAALNTLnqP-DVKIVTVEDPVEYQLDGVNQVQ------VQSAIGLTFSNLLRSFLRQDPDIMLV 327
Cdd:TIGR02788 147 IIISGGTGSGKTTFLKSLVDEI--PkDERIITIEDTREIFLPHPNYVHlfyskgGQGLAKVTPKDLLQSCLRMRPDRIIL 224
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1162406145 328 GEIRDVETADIaIQSALTGHM-VFSTLHTNDSLGAITRLEDM 368
Cdd:TIGR02788 225 GELRGDEAFDF-IRAVNTGHPgSITTLHAGSPEEAFEQLALM 265
T2SSE_N pfam05157
Type II secretion system (T2SS), protein E, N-terminal domain; This domain is found at the ...
2-82 4.44e-12

Type II secretion system (T2SS), protein E, N-terminal domain; This domain is found at the N-terminus of members of the Type II secretion system protein E. Proteins in this subfamily are typically involved in Type 4 pilus biogenesis, though some are involved in other processes; for instance aggregation in Myxococcus xanthus. The structure of this domain is now known.


Pssm-ID: 428339 [Multi-domain]  Cd Length: 108  Bit Score: 62.74  E-value: 4.44e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145   2 LDAADFPETPPALTGLPLSFMKRFLALPVEIADDRVVVVMADPMDFSTREIISRTFDRPVLIRRAEAETISQYIYRWFEA 81
Cdd:pfam05157  25 VDLEALEIDPELLRLLPREFARRHRVLPLREDGGTLVVAVADPLDLALLDELRFLTGKRVEPVLATPSDIRRALERLYGS 104

                  .
gi 1162406145  82 E 82
Cdd:pfam05157 105 E 105
PRK13833 PRK13833
conjugal transfer protein TrbB; Provisional
255-371 4.77e-11

conjugal transfer protein TrbB; Provisional


Pssm-ID: 172360 [Multi-domain]  Cd Length: 323  Bit Score: 64.05  E-value: 4.77e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 255 ILVTGPTGSGKTTTLYAALNTL--NQPDVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFSNLLRSFLRQDPDIMLVGEIRD 332
Cdd:PRK13833  147 IVISGGTGSGKTTLANAVIAEIvaSAPEDRLVILEDTAEIQCAAENAVALHTSDTVDMARLLKSTMRLRPDRIIVGEVRD 226
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1162406145 333 vETADIAIQSALTGHM-VFSTLHTNDSLGAITRLEDMGVE 371
Cdd:PRK13833  227 -GAALTLLKAWNTGHPgGVTTIHSNTAMSALRRLEQLTAE 265
PRK13851 PRK13851
type IV secretion system protein VirB11; Provisional
255-365 4.23e-08

type IV secretion system protein VirB11; Provisional


Pssm-ID: 172375  Cd Length: 344  Bit Score: 54.90  E-value: 4.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 255 ILVTGPTGSGKTT---TLYAALntlnQPDVKIVTVEDPVEYQLDGVNQVQV---QSAIGL---TFSNLLRSFLRQDPDIM 325
Cdd:PRK13851  165 MLLCGPTGSGKTTmskTLISAI----PPQERLITIEDTLELVIPHENHVRLlysKNGAGLgavTAEHLLQASLRMRPDRI 240
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1162406145 326 LVGEIRDvETADIAIQSALTGHM-VFSTLHTNDSLGAITRL 365
Cdd:PRK13851  241 LLGEMRD-DAAWAYLSEVVSGHPgSISTIHGANPVQGFKKL 280
PRK13900 PRK13900
type IV secretion system ATPase VirB11; Provisional
223-368 4.92e-07

type IV secretion system ATPase VirB11; Provisional


Pssm-ID: 184381  Cd Length: 332  Bit Score: 51.68  E-value: 4.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 223 KQDEINLDLDSLGFPDTIRRQFEQAIKLPYGmILVTGPTGSGKTTTLYAALNTLNQpDVKIVTVEDPVEYQL-DGVNQVQ 301
Cdd:PRK13900  132 LVDEDDVILNELLAEKKIKEFLEHAVISKKN-IIISGGTSTGKTTFTNAALREIPA-IERLITVEDAREIVLsNHPNRVH 209
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1162406145 302 VQSAIG------LTFSNLLRSFLRQDPDIMLVGEIRDVEtADIAIQSALTGHM-VFSTLHTNDSLGAITRLEDM 368
Cdd:PRK13900  210 LLASKGgqgrakVTTQDLIEACLRLRPDRIIVGELRGAE-AFSFLRAINTGHPgSISTLHADSPAMAIEQLKLM 282
AAA_22 pfam13401
AAA domain;
253-289 6.00e-04

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 40.02  E-value: 6.00e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1162406145 253 GMILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDP 289
Cdd:pfam13401   6 GILVLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLP 42
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
251-330 6.31e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.43  E-value: 6.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145  251 PYGMILVTGPTGSGKTTTLYAALNTLNQP--DVKIVTVEDPVEYQLDGVNQVQVQSAIGLTFS----NLLRSFLRQ-DPD 323
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPggGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGelrlRLALALARKlKPD 80

                   ....*..
gi 1162406145  324 IMLVGEI 330
Cdd:smart00382  81 VLILDEI 87
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
245-289 9.67e-04

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 40.93  E-value: 9.67e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1162406145 245 EQAIKLPYGMILVTGPTGSGKTTTLYAALNTLNqPDVKIVTVEDP 289
Cdd:COG3267    36 EYALAQGGGFVVLTGEVGTGKTTLLRRLLERLP-DDVKVAYIPNP 79
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
238-330 6.45e-03

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 37.51  E-value: 6.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1162406145 238 DTIRRQFEQAIKLPYGM-ILVTGPTGSGKTTTLYAALNTLNQPDVKIVTVEDPVEYQLDgvnqvQVQSAIGLTFSNLLRS 316
Cdd:cd00009     4 EEAIEALREALELPPPKnLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGL-----VVAELFGHFLVRLLFE 78
                          90
                  ....*....|....*
gi 1162406145 317 FLRQ-DPDIMLVGEI 330
Cdd:cd00009    79 LAEKaKPGVLFIDEI 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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