|
Name |
Accession |
Description |
Interval |
E-value |
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
3-386 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 580.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 3 NFETLAIRTQIE-RSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFAT 81
Cdd:COG0626 2 GPATRAVHAGRDpDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 82 GMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILD 161
Cdd:COG0626 82 GMAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVVD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 162 LEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIRE-IYLFARNTGPAMSP 240
Cdd:COG0626 162 IAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAErLRFLQNALGAVLSP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 241 FNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFL 320
Cdd:COG0626 242 FDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAARRFL 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160601572 321 DKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:COG0626 322 DALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALA 387
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
3-386 |
0e+00 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 561.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 3 NFETLAIRTQIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PRK08133 6 GFDTLAVRAGQLRSPFGEHSEALFLTSSFVFESAAEAAARFAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACVATASG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDL 162
Cdd:PRK08133 86 MAAILAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELADI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 163 EFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNTGPAMSPFN 242
Cdd:PRK08133 166 AALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFLRTAGPTLSPFN 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 243 AWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDK 322
Cdd:PRK08133 246 AWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAWRVIDA 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1160601572 323 IKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK08133 326 TRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLA 389
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
3-386 |
3.81e-175 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 494.55 E-value: 3.81e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 3 NFETLAIRT-QIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFAT 81
Cdd:COG2873 7 GFETLALHAgQEPDPTTGARAVPIYQTTSYVFDDAEHAADLFALKEPGNIYTRIMNPTTDVLEKRIAALEGGVAALATAS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 82 GMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILD 161
Cdd:COG2873 87 GQAAITLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPALDVLD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 162 LEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV----------GR----------- 220
Cdd:COG2873 167 IEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVdggnfdwaanGKfpeltepdpsy 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 221 ------EDL--------IREIYLfaRNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLK 286
Cdd:COG2873 247 hglvytEAFgnaafitkARVQLL--RDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYPGLP 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 287 SHPSYEVAKKQMKLG-GNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLV 365
Cdd:COG2873 325 SHPYHELAQKYLPKGaGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVTPDLI 404
|
410 420
....*....|....*....|.
gi 1160601572 366 RCSVGLENVEDIIADLKQALD 386
Cdd:COG2873 405 RLSVGIEDIDDIIADLDQALA 425
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
22-386 |
1.58e-172 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 485.55 E-value: 1.58e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 22 STPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIV 101
Cdd:cd00614 4 APPIYQTSTFVFPSPAEAADLFALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALLKAGDHVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 102 SCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC 181
Cdd:cd00614 84 ASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVVDNT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 182 FATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGR-EDLIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKH 260
Cdd:cd00614 164 FATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSgEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRMERH 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 261 CENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVT 340
Cdd:cd00614 244 SENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVESLVE 323
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1160601572 341 HPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:cd00614 324 HPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
5-386 |
1.30e-170 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 480.96 E-value: 1.30e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 5 ETLAIRTQIERS-QFDEHSTPLYLTSSFVFedaedmraSFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGM 83
Cdd:pfam01053 1 DTLAVHAGQRPDpQTGAVSVPIYLTSTYVF--------DFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 84 AAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLE 163
Cdd:pfam01053 73 AAITAAILALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 164 FFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGR-EDLIREIYLFARNTGPAMSPFN 242
Cdd:pfam01053 153 AIAKLAKKHGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNgEELGKELYFLQNATGAVLSPFD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 243 AWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDK 322
Cdd:pfam01053 233 AWLLLRGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDN 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1160601572 323 IKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:pfam01053 313 LKLFSLAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
5-385 |
1.08e-167 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 473.95 E-value: 1.08e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 5 ETLAIRTQIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMA 84
Cdd:TIGR01325 1 ATLAVRGGMLRSGFEETAEALYLTSGYVYDSAAVAAKRFAGELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 85 AIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEF 164
Cdd:TIGR01325 81 AIFAALMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 165 FGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYL-FARNTGPAMSPFNA 243
Cdd:TIGR01325 161 VAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEYMDEPVQkLLRHTGPAMSPFNA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 244 WVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGiEGGRNFLDKI 323
Cdd:TIGR01325 241 WVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSHPQHELAKRQMSGGGTVVTFDLDCR-QAAFKVLDAM 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160601572 324 KMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:TIGR01325 320 RLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
5-385 |
6.13e-154 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 439.94 E-value: 6.13e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 5 ETLAIRTQIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMA 84
Cdd:PRK07810 17 ATIGVRGGLLRSGFEETAEALYLTSGYVYESAAAAEAAFTGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 85 AIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEF 164
Cdd:PRK07810 97 AVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 165 FGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIRE-IYLFARNTGPAMSPFNA 243
Cdd:PRK07810 177 VSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGpVQKLMRHTGPALSAFNA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 244 WVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRN----F 319
Cdd:PRK07810 257 WVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPEDAAKKrafeV 336
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160601572 320 LDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK07810 337 LDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
4-386 |
2.58e-152 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 435.41 E-value: 2.58e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 4 FETLAIRT-QIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PRK06234 9 FATKAIHGgHIGDKQFGSLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDL 162
Cdd:PRK06234 89 MGAISSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 163 EFFGQIAKKHN--LIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARN--TGPAM 238
Cdd:PRK06234 169 KAISNIAHENNkeCLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVKLFGIKdmTGSVI 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 239 SPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRN 318
Cdd:PRK06234 249 GPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEEGKV 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1160601572 319 FLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK06234 329 VMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALD 396
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
3-385 |
6.24e-152 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 435.25 E-value: 6.24e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 3 NFETLAIRT-QIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFAT 81
Cdd:TIGR01326 1 HFETLQLHAgQEPDPTTGSRAVPIYQTTSYVFDSTEHAAALFGLQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAVAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 82 GMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILD 161
Cdd:TIGR01326 81 GQAAITYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 162 LEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV---------GR------------ 220
Cdd:TIGR01326 161 IEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVdggkfdwnnGRfplfttpdpsyh 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 221 -----EDLIREIYLFA------RNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHP 289
Cdd:TIGR01326 241 glvftETLGNPAFILKarvqllRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASHP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 290 SYEVAKKQMKLG-GNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCS 368
Cdd:TIGR01326 321 HHALAKKYLPKGfGAVLSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRLS 400
|
410
....*....|....*..
gi 1160601572 369 VGLENVEDIIADLKQAL 385
Cdd:TIGR01326 401 VGIENIDDIIADLEQAL 417
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
15-386 |
3.52e-144 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 414.92 E-value: 3.52e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 15 RSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLL 94
Cdd:PRK07504 22 RSQFGETSEALFLTQGFVYDTAEAAEARFKGEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATASGMAAVTAAILCQV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 95 NAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNL 174
Cdd:PRK07504 102 KAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGA 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 175 IFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIRE-IYLFARNTGPAMSPFNAWVLSKSLETL 253
Cdd:PRK07504 182 KLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEhLQDYFRHTGPSLSPFNAWTLLKGLETL 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 254 AIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKIKMCSLSANLG 333
Cdd:PRK07504 262 PVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRFLNALKIVRISNNLG 341
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1160601572 334 DTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK07504 342 DAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALK 394
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
3-386 |
1.23e-134 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 389.97 E-value: 1.23e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 3 NFETLAIRTQIERSQ-FDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFAT 81
Cdd:PRK06767 5 HMETALIHHGYTSEEhKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEALAFGS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 82 GMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILD 161
Cdd:PRK06767 85 GMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKLID 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 162 LEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFAR-NTGPAMSP 240
Cdd:PRK06767 165 LKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRkDIGGIMAP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 241 FNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYpflkshPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFL 320
Cdd:PRK06767 245 FDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEETQAFI 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160601572 321 DKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK06767 319 NDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALK 384
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
24-386 |
7.09e-133 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 386.46 E-value: 7.09e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 24 PLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIVSC 103
Cdd:PRK07503 31 PVYLTATFAFPTAEYGAECFAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMGAITATLWTLLRPGDEVIVD 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 104 QSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNCFA 183
Cdd:PRK07503 111 QTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAAVAEIAHGAGAKVVVDNTYC 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 184 TPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARN--TGPAMSPFNAWVLSKSLETLAIRVEKHC 261
Cdd:PRK07503 191 TPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIRLEGLKdmTGAVMSPFDAFLLMRGLKTLALRMDRHC 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 262 ENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTH 341
Cdd:PRK07503 271 ASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAAGRRFMNALQLFARAVSLGDAESLAQH 350
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1160601572 342 PASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK07503 351 PASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
22-385 |
5.26e-124 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 364.84 E-value: 5.26e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 22 STPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAiySTFA--TLLNAGDH 99
Cdd:PRK07812 33 ALPIYQTTSYTFDDTDHAAALFGLAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQAA--ETFAilNLAGAGDH 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 100 IVSCQSVFGSTHTLFTKYFPKWNIETTYfkAEDSENVEKY---IKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIF 176
Cdd:PRK07812 111 IVSSPRLYGGTYNLFHYTLPKLGIEVSF--VEDPDDLDAWraaVRPNTKAFFAETISNPQIDVLDIPGVAEVAHEAGVPL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 177 IVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV--GREDLIREIY-------------LFA---------- 231
Cdd:PRK07812 189 IVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdgGTFDWTQGRFpgfttpdpsyhgvVFAelgppayalk 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 232 ------RNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLG-GNI 304
Cdd:PRK07812 269 arvqllRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPWYERAKRLAPKGtGAV 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 305 VAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQA 384
Cdd:PRK07812 349 LSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVGIEGIDDILADLEAG 428
|
.
gi 1160601572 385 L 385
Cdd:PRK07812 429 F 429
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
23-386 |
7.45e-124 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 363.29 E-value: 7.45e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 23 TPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIVS 102
Cdd:PRK08249 29 VPVVLSVAYGYDDIDEWYDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTFLKPGDRVVS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 103 CQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNCF 182
Cdd:PRK08249 109 IKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAKKVGALVVVDNTF 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 183 ATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKHCE 262
Cdd:PRK08249 189 ATPINQNPLALGADLVIHSATKFLSGHADALGGVVCGSKELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRVRQQQE 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 263 NALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHP 342
Cdd:PRK08249 269 SAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKRLLPKLRYAHRAANLGAVETIYGPA 348
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1160601572 343 ASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK08249 349 RTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFA 392
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
4-385 |
1.65e-123 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 363.67 E-value: 1.65e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 4 FETLAIRT-QIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PRK08134 9 FDTLALHAgAAPDPATGARAVPIHLTTSFVFRDSDHAAALFNLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDL 162
Cdd:PRK08134 89 QAALHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 163 EFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV----------GREDLIREIY---- 228
Cdd:PRK08134 169 PTVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVdggrfdweasGKFPELTEPYagfh 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 229 --LFARNTGPA-----------------MSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHP 289
Cdd:PRK08134 249 gmVFAEESTVAafllrarreglrdfgacLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 290 SYEVAKKQMKLG-GNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCS 368
Cdd:PRK08134 329 DHALAKRLLPRGaGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLS 408
|
410
....*....|....*..
gi 1160601572 369 VGLENVEDIIADLKQAL 385
Cdd:PRK08134 409 IGLEDADDLIDDLKRAL 425
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
5-385 |
5.92e-121 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 356.85 E-value: 5.92e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 5 ETLAIRT--QIERSQFdEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PRK08248 10 ETLAIHAgqEIDPTTG-SRAVPIYQTTSYGFRDSEHAANLFSLKEFGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDL 162
Cdd:PRK08248 89 QAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 163 EFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV--GRED------------------ 222
Cdd:PRK08248 169 EAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsGKFDwkgsgkfpgltepdpsyh 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 223 -------------LIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHP 289
Cdd:PRK08248 249 glvytdavgeaayITKARVQLLRDLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPSHP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 290 SYEVAKKQMKLG-GNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCS 368
Cdd:PRK08248 329 SYELAKKYLPKGqGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVRLS 408
|
410
....*....|....*..
gi 1160601572 369 VGLENVEDIIADLKQAL 385
Cdd:PRK08248 409 VGTEAIDDILDDLRQAI 425
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
4-385 |
8.19e-115 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 340.92 E-value: 8.19e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 4 FETLAIRTQierSQFD----EHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAF 79
Cdd:PRK05994 8 FATLAVHAG---AQPDpttgARATPIYQTTSFVFNDADHAASLFGLQAFGNIYTRITNPTNAVLEERVAALEGGTAALAV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 80 ATGMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEI 159
Cdd:PRK05994 85 ASGHAAQFLVFHTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 160 LDLEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV----------GREDLIRE--- 226
Cdd:PRK05994 165 TDIAAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIVdggtfdwsksGKYPMLSEprp 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 227 ----IYL--------FA--------RNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLK 286
Cdd:PRK05994 245 eyhgLVLhetfgnfaFAiaarvlglRDLGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLP 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 287 SHPSYEVAKKQMKLG-GNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLV 365
Cdd:PRK05994 325 DDPYHALAQKYSPKGaGAVFTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVV 404
|
410 420
....*....|....*....|
gi 1160601572 366 RCSVGLENVEDIIADLKQAL 385
Cdd:PRK05994 405 RLSIGIEDVDDIIADLEQAL 424
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
19-386 |
1.63e-114 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 338.62 E-value: 1.63e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 19 DEH----STPLYLTSSFVFEDAEdmrasfaeEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFaTLL 94
Cdd:PRK07671 15 DPStgavSVPIYQVSTYKQEAVG--------KHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVM-MLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 95 NAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNL 174
Cdd:PRK07671 86 SSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEKGL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 175 IFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGG-VAVGREDLIREIYLFARNTGPAMSPFNAWVLSKSLETL 253
Cdd:PRK07671 166 LTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGlVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKTL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 254 AIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIkGGIEGGRNFLDKIKMCSLSANLG 333
Cdd:PRK07671 246 GIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLAESLG 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1160601572 334 DTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK07671 325 AVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
4-386 |
1.74e-114 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 338.93 E-value: 1.74e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 4 FETLAIRTQIErsqFDEHS----TPLYLTSSFVFEDAEDMRASFAeeksknlYSRFSNPNVTEFTDKIVKMEGAEAGYAF 79
Cdd:PRK07811 13 FATRAIHAGYE---PDPATgavnPPIYASSTFAQDGVGGLRGGYE-------YARTGNPTRTALEEQLAALEGGAYGRAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 80 ATGMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEI 159
Cdd:PRK07811 83 SSGMAATDCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 160 LDLEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNT-GPAM 238
Cdd:PRK07811 163 TDIAALAELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGaGAVP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 239 SPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRN 318
Cdd:PRK07811 243 GPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGEEAARD 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1160601572 319 FLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDeerNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK07811 323 FCARTKVFTLAESLGGVESLIEHPSAMTHASTAG---SQLEVPDDLVRLSVGIEDVADLLADLEQALG 387
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
6-385 |
4.62e-106 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 317.39 E-value: 4.62e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 6 TLAIRTQIERSQFDEHSTPLYLTSSFVFEDaedmRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAA 85
Cdd:PRK08574 5 TDAVRGYRGSDPYGSLQPPIYLTALFRQEG----EAYPSDRGFDLKYSREENPTLRPLEEALAKLEGGVDALAFNSGMAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 86 IYSTFATLLNAGDHIVSCQSVFGSTHTLFtKYFPKWNIET--TYFKAEDSenVEKYIKPNTKILYLETPTNPAIEILDLE 163
Cdd:PRK08574 81 ISTLFFSLLKAGDRVVLPMEAYGTTLRLL-KSLEKFGVKVvlAYPSTEDI--IEAIKEGRTKLVFIETMTNPTLKVIDVP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 164 FFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV-GREDLIREIYLFARNTGPAMSPFN 242
Cdd:PRK08574 158 EVAKAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVaWSGEFLEELWEWRRRLGTIMQPFE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 243 AWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLG--GNIVAFEIKGGIEGGRNFL 320
Cdd:PRK08574 238 AYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRLFGKDlyGGVVSFRVKGGRDAVLKFL 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160601572 321 DKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK08574 318 RSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQAL 382
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
22-386 |
3.90e-105 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 316.46 E-value: 3.90e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 22 STPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIV 101
Cdd:PRK06084 22 AVPIYQTTSYAFDDTQHGADLFDLKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVASGMAAITYAIQTIAEAGDNIV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 102 SCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC 181
Cdd:PRK06084 102 SVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDIQALADAAHRHGVPLIVDNT 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 182 FATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV--GREDLIREIYLFA---------------------------- 231
Cdd:PRK06084 182 VATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVdsGKFPWAEHKERFAllntpdpsyhgvtyteafgpaafigrcr 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 232 ----RNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMklGG---NI 304
Cdd:PRK06084 262 vvplRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPDHPEHELARRYM--GGkpaSI 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 305 VAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQA 384
Cdd:PRK06084 340 LSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVRLSIGIEHIDDIIADLAQA 419
|
..
gi 1160601572 385 LD 386
Cdd:PRK06084 420 LD 421
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
24-386 |
1.02e-104 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 314.32 E-value: 1.02e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 24 PLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIVSC 103
Cdd:PRK05939 13 PIHTSVTYGYEDARDLIDVFQGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLLRAGDHLVSS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 104 QSVFGSTHTLFTKyFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNCFA 183
Cdd:PRK05939 93 QFLFGNTNSLFGT-LRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLYVVDNTMT 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 184 TPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV--GREDL-----IREIYLFA---------------RNTGPAMSPF 241
Cdd:PRK05939 172 SPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtGLFDWsaypnIFPAYRKGdpqqwgltqirkkglRDMGATLSSE 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 242 NAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEgGRNFLD 321
Cdd:PRK05939 252 AAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELADGID-CFDFLN 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160601572 322 KIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK05939 331 RLKLVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALD 395
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
4-386 |
4.51e-104 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 314.12 E-value: 4.51e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 4 FETLAIRT-QIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PRK05613 14 FETRSIHAgQSVDSDTSARNLPIYQTTSYVFDSAEHAKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAVAFASG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFK-AEDSENVEKYIKPNTKILYLETPTNPAIEILD 161
Cdd:PRK05613 94 QAAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVEnPDDPESWQAAVQPNTKAFFGETFANPQADVLD 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 162 LEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV--GREDLIRE------------- 226
Cdd:PRK05613 174 IPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdgGKFDWTVErdgkpvfpyfvtp 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 227 --IY-----------LFA--------RNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFL 285
Cdd:PRK05613 254 dpAYhglkyadlgapAFGlkaragllRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAGL 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 286 KSHPSYEVAKK-QMKLGGNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGL 364
Cdd:PRK05613 334 KDSPWYATKEKlGLKYTGSVLSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQAT 413
|
410 420
....*....|....*....|..
gi 1160601572 365 VRCSVGLENVEDIIADLKQALD 386
Cdd:PRK05613 414 VRLSVGIEDIDDIIADLEGGFA 435
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
22-385 |
9.32e-102 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 306.05 E-value: 9.32e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 22 STPLYLTSSFvfedaedmRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFaTLLNAGDHIV 101
Cdd:PRK06176 22 SVPIYQTSTY--------RQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAVF-SLFQSGDHVL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 102 SCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC 181
Cdd:PRK06176 93 LGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 182 FATPYLQQPIKYGADIVVHSATKLIDGQGRVLGG-VAVGREDLIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKH 260
Cdd:PRK06176 173 FATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGlVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAH 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 261 CENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGiEGGRNFLDKIKMCSLSANLGDTRTIVT 340
Cdd:PRK06176 253 QKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKND-SEAVAFVESLKLFILGESLGGVESLVG 331
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1160601572 341 HPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK06176 332 IPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAF 376
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
22-385 |
2.74e-101 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 304.83 E-value: 2.74e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 22 STPLYLTSSFVFEDAEDMRasfaeeksknlYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIV 101
Cdd:PRK06460 20 TTPIYQTTAYHYPEGEKYR-----------YSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLKPGNSVL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 102 SCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC 181
Cdd:PRK06460 89 VHRDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENGSILIVDAT 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 182 FATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKHC 261
Cdd:PRK06460 169 FSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGKLLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVIN 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 262 ENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKIKMCSLSANLGDTRTIVTH 341
Cdd:PRK06460 249 RNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIPAQTLGGVNSVISH 328
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1160601572 342 PASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK06460 329 PATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRAL 372
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
1-385 |
2.56e-99 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 299.31 E-value: 2.56e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 1 MENFETLAIrtQI-ERSqfDEH----STPLYLTSSFvfedaedmRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEA 75
Cdd:PRK08247 2 MSTIETKLA--QIgNRS--DERtgtvNPPVYFSTAY--------RHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 76 GYAFATGMAAIYSTFAtLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNP 155
Cdd:PRK08247 70 GFACSSGMAAIQLVMS-LFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 156 AIEILDLEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGR-EDLIREIYLFARNT 234
Cdd:PRK08247 149 LMQETDIAAIAKIAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKgQELCERLAYYQNAA 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 235 GPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPflkshpsyevAKkqmklgGNIVAFEIKGgiE 314
Cdd:PRK08247 229 GAVLSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYP----------GR------GGMLSFRLQD--E 290
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160601572 315 GGRN-FLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK08247 291 EWVNpFLKSLKLITFAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAF 362
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
22-386 |
9.40e-99 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 298.61 E-value: 9.40e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 22 STPLYLTSSFVFEDAEDMrasfaeekSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFaTLLNAGDHIV 101
Cdd:PRK08064 26 NVPIYHASTFHQFDFDTF--------GKYDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAF-LLLSKGDHVL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 102 SCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC 181
Cdd:PRK08064 97 ISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKAIGCLTFVDNT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 182 FATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGR-EDLIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKH 260
Cdd:PRK08064 177 FLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKdEELAQKLYFLQNSFGAVLGVQDCWLVLRGLKTLHVRLEHS 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 261 CENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIkGGIEGGRNFLDKIKMCSLSANLGDTRTIVT 340
Cdd:PRK08064 257 SETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTL-QSEEAVRQFVSHVKLPVFAVSLGAVESILS 335
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1160601572 341 HPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK08064 336 YPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALS 381
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
24-386 |
6.66e-93 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 285.03 E-value: 6.66e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 24 PLYLTSSFVFEDAEDMRASF----------AEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATL 93
Cdd:PRK07049 39 PVFLTSTFVFRSAEDGRDFFdyvsgrkeppAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIATTLLAF 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 94 LNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKA-EDSENVEKYI-----KPNTKILYLETPTNPAIEILDLEFFGQ 167
Cdd:PRK07049 119 VRPGDVILHSQPLYGGTETLLAKTFRNFGVGAVGFADgLSEAAIGAAAeaaaaKGRVSLILIETPANPTNSLVDVAAVRR 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 168 IAKK------HNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFaRNT-GPAMSP 240
Cdd:PRK07049 199 VADAiearqgHRPIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAVLGRKALIRQVRAL-RSAiGTQLDP 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 241 FNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKY-PFLKSHPSY-EVAKKQMKLGGNIVAFEIKGGIEGGRN 318
Cdd:PRK07049 278 HSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYlPFLDPDSAYgAVYKRQCTGAGSTFSFDIKGGQAAAFR 357
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1160601572 319 FLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK07049 358 FLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQALD 425
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
6-385 |
4.34e-90 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 276.32 E-value: 4.34e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 6 TLAIRTQIERSQFDEHSTPLYLTSSFVFEDAEdmrasfaeEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAA 85
Cdd:TIGR01329 3 TLLVNTDNKNDPYDASSMPIYQTATFKQPLAI--------ENGPYDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 86 IySTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFF 165
Cdd:TIGR01329 75 L-DVITRLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKI 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 166 GQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGV-AVGREDLIREIYLFARNTGPAMSPFNAW 244
Cdd:TIGR01329 154 SEMAHAQNALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVlAVKGEEIAKKVYFLQNSTGSGLAPFDCW 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 245 VLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEiKGGIEGGRNFLDKIK 324
Cdd:TIGR01329 234 LLLRGIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFE-TGSVALSKRLVEATK 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1160601572 325 MCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:TIGR01329 313 LFSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
18-385 |
1.10e-86 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 267.72 E-value: 1.10e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 18 FDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAG 97
Cdd:PRK05968 23 FDAVVPPIFQTSLFTFDSYDEMEDVYAGEKVRPIYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISSTVLSFVEPG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 98 DHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIkPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFI 177
Cdd:PRK05968 103 DRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESPTSWVFELQDVAALAALAKRHGVVTM 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 178 VDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREI------YLfarntGPAMSPFNAWVLSKSLE 251
Cdd:PRK05968 182 IDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARInaeaypYL-----GAKLSPFEAWLLLRGLR 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 252 TLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPsyevaKKQMKLGGNIVAFEIKGGIEgGRNFLDKIKMCSLSAN 331
Cdd:PRK05968 257 TLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHP-----PAGLSGTSGLFSFIFREGID-VRAFADALKLFRLGVS 330
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1160601572 332 LGDTRTIVThPASTThsrLSDEERNEV----GITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK05968 331 WGGHESLVV-PAEVV---LQQKAQPNSaarfGVSPRSVRLHVGLEGTEALWADLEQAL 384
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
24-385 |
5.12e-84 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 262.30 E-value: 5.12e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 24 PLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIVSC 103
Cdd:PRK06702 27 PLYQSTTYKYDTSDDLAALFNLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAAIMLAVLNICSSGDHLLCS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 104 QSVFGSTHTLFTKYFPKWNIETTYFKAE-DSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNCF 182
Cdd:PRK06702 107 STVYGGTFNLFGVSLRKLGIDVTFFNPNlTADEIVALANDKTKLVYAESLGNPAMNVLNFKEFSDAAKELEVPFIVDNTL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 183 ATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAV--GRED------------------------------LIREIYLF 230
Cdd:PRK06702 187 ATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdgGNFDwtngkypelvepdpsyhgvsyvqnfgaaayIVKARVQL 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 231 ARNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGN-IVAFEI 309
Cdd:PRK06702 267 LRDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNENYSLAQKYLKKGASgVLTFGI 346
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1160601572 310 KGGIEGGRNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK06702 347 KGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLSVGIEDVSDIIADLEAAL 422
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
3-385 |
1.66e-81 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 256.88 E-value: 1.66e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 3 NFETLAIRTQIERSQFDEHSTPLYLTSSFvfedaedmRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PLN02509 86 SVSTLLVNLDNKFDPFDAMSTPLYQTATF--------KQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSG 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIySTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDL 162
Cdd:PLN02509 158 MAAL-SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDI 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 163 EFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGV-AVGREDLIREIYLFARNTGPAMSPF 241
Cdd:PLN02509 237 RKIAEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVlAVKGEKLAKEVYFLQNSEGSGLAPF 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 242 NAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFeIKGGIEGGRNFLD 321
Cdd:PLN02509 317 DCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALSKHLVE 395
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1160601572 322 KIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PLN02509 396 TTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
6-385 |
2.12e-80 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 252.22 E-value: 2.12e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 6 TLAIRTQIER-SQFDEHSTPLYLTSSFVFEdaedmraSFAEEKSKNlYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMA 84
Cdd:PRK08776 15 TAAVRAGIDRdTAYGAVTPPIVLSSNFSFD-------GFGNKRQYD-YTRSGNPTRDLLGEALAELEGGAGGVITATGMG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 85 AIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEF 164
Cdd:PRK08776 87 AINLVLNALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 165 FGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGRE-DLIREIYLFARNTGPAMSPFNA 243
Cdd:PRK08776 167 VIEAAHKVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDaELHQQLVWWANALGLTGSPFDA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 244 WVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKI 323
Cdd:PRK08776 247 FLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVDGL 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160601572 324 KMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK08776 327 RYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
6-384 |
3.73e-77 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 243.26 E-value: 3.73e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 6 TLAIRTQIER-SQFDEHSTPLYLTSSFVFedaedmrASFAEEKSKNlYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMA 84
Cdd:PRK08861 8 TIAVRTGIESdSQYHAVVPPIYLSTNYGF-------PAFGEVPKYD-YTRSGNPNRGLLEQTLSELESGKGAVVTNCGTS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 85 AIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEF 164
Cdd:PRK08861 80 ALNLWVSALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 165 FGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGR-EDLIREIYLFARNTGPAMSPFNA 243
Cdd:PRK08861 160 LCQKAKAVGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKtKEHAEELAWWGNCIGATGTPFDS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 244 WVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKI 323
Cdd:PRK08861 240 YMTLRGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKVFVKAL 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1160601572 324 KMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQA 384
Cdd:PRK08861 320 ALFSLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQA 380
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
4-386 |
1.03e-76 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 242.12 E-value: 1.03e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 4 FETLAIRT-QIERSQFDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATG 82
Cdd:PRK06434 9 FNTRAVQSgELRDPRFGNVTTPIFETSTFVYPNSEKEAYMDSTRGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 83 MAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEkYIKPNTKILYLETPTNPAIEILDL 162
Cdd:PRK06434 89 MGAITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLD-FDPSNYDLIYAESITNPTLKVPDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 163 EFFGQIAKKHNLIFivDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNT-GPAMSPF 241
Cdd:PRK06434 168 KNVSSFCHENDVIV--DATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTlGSNPDPI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 242 NAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLkshpsyEVAKKQMKLGGNIVAFEIKGgIEGGRNFLD 321
Cdd:PRK06434 246 QAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELRS-MEDVHKFIR 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1160601572 322 KIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK06434 319 NLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALS 383
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
15-370 |
9.59e-73 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 232.73 E-value: 9.59e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 15 RSQFDEH---STPLYLTSSFVFEDAEDMRASFAEE----KSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIY 87
Cdd:PLN02242 26 RHEFGEHggvNMSIEASATFTVMEPDTMRRMFSGElgpdRDFYIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAIS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 88 STFATLLNAGDHIVSCQSVFGSTHTLFTKYFP-KWNIETTYFKAEDSENVEKYIKPN-TKILYLETPTNPAIEILDLEFF 165
Cdd:PLN02242 106 SVLLQLCSSGGHVVASNTLYGGTHALLAHFLPrKCNITTTFVDITDLEAVKKAVVPGkTKVLYFESISNPTLTVADIPEL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 166 GQIAKKHNLIFIVDNCFAtPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNT----GPAMSPF 241
Cdd:PLN02242 186 ARIAHEKGVTVVVDNTFA-PMVLSPARLGADVVVHSISKFISGGADIIAGAVCGPAELVNSMMDLHHGAlmllGPTMNPK 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 242 NAWVLSKSLETLAIRVEKHCENALKVAEFLEshpnvEL---TKYPFLKSHPSYEVAKKQMKLG---GNIVAFEIkGGIEG 315
Cdd:PLN02242 265 VAFELSERLPHLSLRMKEHCRRAMEYAKRMK-----ELglkVIYPGLEDHPQHALLKSMANKGygfGGLLCLDM-DTEER 338
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1160601572 316 GRNFLDKIKMCS----LSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVG 370
Cdd:PLN02242 339 ANRLMRYLQNSTqfgfMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVG 397
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
6-385 |
9.78e-72 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 229.40 E-value: 9.78e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 6 TLAIRTQI-ERSQFDEHSTPLYLTSSFVFEDAEDMRAsfaeekskNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMA 84
Cdd:PRK08045 7 TIAVRSGLnDDEQYGCVVPPIHLSSTYNFTGFNEPRA--------HDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 85 AIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEF 164
Cdd:PRK08045 79 AIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 165 FGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGRE-DLIREIYLFARNTGPAMSPFNA 243
Cdd:PRK08045 159 ICHLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDpDVVTELAWWANNIGVTGGAFDS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 244 WVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRNFLDKI 323
Cdd:PRK08045 239 YLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGL 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1160601572 324 KMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK08045 319 SLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGF 380
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
45-386 |
1.42e-65 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 212.55 E-value: 1.42e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 45 EEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAgYAFATGMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIE 124
Cdd:PRK07582 38 EPTGPDTYGRASNPTWRALEAALGELEGAEA-LVFPSGMAAITAVLRALLRPGDTVVVPADGYYQVRALAREYLAPLGVT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 125 -----TTYFKAEDSENVekyikpntKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVV 199
Cdd:PRK07582 117 vreapTAGMAEAALAGA--------DLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTATPLGQRPLELGADLVV 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 200 HSATKLIDGQGRVLGG-VAVGREDLIREIYLFARNTGPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVE 278
Cdd:PRK07582 189 ASDTKALTGHSDLLLGyVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCANALAVAELLAGHPAVR 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 279 LTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIkGGIEGGRNFLDKIKMCSLSANLGDTRTivthpastthsrlSDEERNEV 358
Cdd:PRK07582 269 GVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASRLVVAATSFGGVHT-------------SADRRARW 334
|
330 340 350
....*....|....*....|....*....|
gi 1160601572 359 G--ITAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK07582 335 GdaVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
52-386 |
3.71e-58 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 193.50 E-value: 3.71e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 52 YSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFaTLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAE 131
Cdd:PRK07269 48 YTRTKNPTRAKLEETLAAIESADYALATSSGMSAIVLAF-SVFPVGSKVVAVRDLYGGSFRWFNQQEKEGRFHFTYANTE 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 132 DsENVEKyIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGR 211
Cdd:PRK07269 127 E-ELIAA-IEEDTDIVYIETPTNPLMVEFDIEKVAKLAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHND 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 212 VLGGVAVGREDLIREIYLFARNT-GPAMSPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPS 290
Cdd:PRK07269 205 VLAGVVVTNDLELYEKLFYNLNTtGAVLSPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGKGGMIS 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 291 YEVAKKQmklggnivafEIKggieggrNFLDKIKMCSLSANLGDTRTIVTHPASTTHSRLSDEERNEVGITAGLVRCSVG 370
Cdd:PRK07269 285 FKVADET----------RIP-------HILNSLKVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIG 347
|
330
....*....|....*.
gi 1160601572 371 LENVEDIIADLKQALD 386
Cdd:PRK07269 348 IEDARDLIADLKQALE 363
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
24-386 |
6.71e-58 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 193.41 E-value: 6.71e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 24 PLYLTSSFVFEDAEDMRASFAEEKSKNL-YSRFSNPNVTEFTDKIVKMEGAeAGYA-FATGMAAIYSTFATLLNAGDHIV 101
Cdd:PRK09028 26 PVFRASTVVFDTVAEMRHAAKNRANGEMfYGRRGTPTHFAFQAAIVELEGG-AGTAlYPSGAAAISNALLSFLKAGDHLL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 102 SCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC 181
Cdd:PRK09028 105 MVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQDVPTLSRIAHEHDIVVMLDNT 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 182 FATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGRE---DLIRE-IYLFarntGPAMSPFNAWVLSKSLETLAIRV 257
Cdd:PRK09028 185 WASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATANEkhwDQLREhSYLM----GQCTSPDDVYLAMRGLRTLGVRL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 258 EKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIK-GGIEGGRNFLDKIKMCSLSANLGDTR 336
Cdd:PRK09028 261 AQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDPKAVTALVEGMQHFKMGFSWGGFE 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 1160601572 337 TIVTHPASTTHSRLSDEERNEvgitAGLVRCSVGLENVEDIIADLKQALD 386
Cdd:PRK09028 341 SLILGVFGINKLRTATNWDFS----KPLIRLHIGLEDVDDLIADLEAGFE 386
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
5-385 |
3.45e-52 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 178.46 E-value: 3.45e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 5 ETLAIRTQIERSQFDEHS------TPLYLTSSFVFEDAEDMrasfAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYA 78
Cdd:PRK05967 9 EKAGINTRLAHDGNDPGDyhgfvnPPVVHASTVLFPDAETM----ATRGQKYTYGTRGTPTTDALCKAIDALEGSAGTIL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 79 FATGMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIE 158
Cdd:PRK05967 85 VPSGLAAVTVPFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 159 ILDLEFFGQIAKKHNLIFIVDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFARNTGPAM 238
Cdd:PRK05967 165 MQDIPAIAEAAHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEKCWPQLLEAHGTLGLCA 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 239 SPFNAWVLSKSLETLAIRVEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGRN 318
Cdd:PRK05967 245 GPDDTYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPEKGKA 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1160601572 319 ----FLDKIKMCSLSANLGDTRTIvthpasTTHSRLSDEERNEVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK05967 325 kahaFLDALEIFGLGYSWGGYESL------ALHVKLGDRTVAKAPYAGPVIRLQIGLEDVPDLKADLERGF 389
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
28-382 |
2.31e-44 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 157.94 E-value: 2.31e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 28 TSSFVFEDAEDM-RASFAEEKSKNLYSRfsNPNVTEFT--DKIVKMEGAEAGYAFATGMAAIYSTFATLLNAGDHIVSCQ 104
Cdd:PRK08114 31 ASSLVFDSVEAKkHATRNRANGELFYGR--RGTLTHFSlqEAMCELEGGAGCALYPCGAAAVANAILAFVEQGDHVLMTG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 105 SVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHN--LIFIVDNCF 182
Cdd:PRK08114 109 TAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITMEVHDVPAIVAAVRSVNpdAVIMIDNTW 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 183 ATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGRE---DLIRE-IYLFarntGPAMSPFNAWVLSKSLETLAIRVE 258
Cdd:PRK08114 189 AAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVANArcwEQLREnSYLM----GQMVDADTAYMTSRGLRTLGVRLR 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 259 KHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGR--NFLDKIKMCSLSANLGDTR 336
Cdd:PRK08114 265 QHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKKLTDEQlaNYLDNFSLFSMAYSWGGFE 344
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1160601572 337 TIV--THPASTTHSRLSDeernEVGITAGLVRCSVGLENVEDIIADLK 382
Cdd:PRK08114 345 SLIlaNQPEEIAAIRPAG----EVDFTGTLIRLHIGLEDVDDLIADLA 388
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
18-385 |
2.05e-41 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 149.87 E-value: 2.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 18 FDEHSTPLYLTSSFVFEDAEDMRASFAEEKSKNLYSRFSNPNVTEFTDKIVKMEGAEAGYAFATGMAAIYSTFATLLNAG 97
Cdd:PRK07050 25 FRSFVTPVARASTVVFPDLATMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVYFGLVKAG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 98 DHIVSCQSVFGSTHTLFTKYFPKWNIETTYFKAEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFI 177
Cdd:PRK07050 105 DDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPDVPAITAAARARGVVTA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 178 VDNCFATPYLQQPIKYGADIVVHSATKLIDGQGRVLGGVAVGREDLIREIYLFAR-NTGPAMSPFNAWVLSKSLETLAIR 256
Cdd:PRK07050 185 IDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARmRLGIGVSADDCSLVLRGLPSLQVR 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 257 VEKHCENALKVAEFLESHPNVELTKYPFLKSHPSYEVAKKQMKLGGNIVAFEIKGGIEGGR--NFLDKIKMCSLSANLGD 334
Cdd:PRK07050 265 LAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDERYSPAQvdAFVEALELFAIGWSWGG 344
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1160601572 335 TRTIVThPASTTHSRLSDeerneVGITAGLVRCSVGLENVEDIIADLKQAL 385
Cdd:PRK07050 345 ACSLAM-PYDVASMRTAK-----WPHRGTLVRLYIGLEDEADLIADLEQAL 389
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
82-320 |
3.21e-09 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 57.74 E-value: 3.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 82 GMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFTKY-----FPKWNIETTYFkaEDSENVEKYIKPNTKILYLETPTNPA 156
Cdd:cd00609 68 AQEALSLLLRALLNPGDEVLVPDPTYPGYEAAARLAgaevvPVPLDEEGGFL--LDLELLEAAKTPKTKLLYLNNPNNPT 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 157 IEILDLEFF---GQIAKKHNLIFIVDNCFA--------TPYLQQPIKYGADIVVHSATKLIDGQG-RVlGGVAVGREDLI 224
Cdd:cd00609 146 GAVLSEEELeelAELAKKHGILIISDEAYAelvydgepPPALALLDAYERVIVLRSFSKTFGLPGlRI-GYLIAPPEELL 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 225 REIYLFARNTGPAMSPFNAWVLSKSLET----LAIRVEKHCENALKVAEFLESHPNVELTK-------YPFLKSHPSYEV 293
Cdd:cd00609 225 ERLKKLLPYTTSGPSTLSQAAAAAALDDgeehLEELRERYRRRRDALLEALKELGPLVVVKpsggfflWLDLPEGDDEEF 304
|
250 260
....*....|....*....|....*....
gi 1160601572 294 AKKQMKLGGNIVafeIKGGIEG--GRNFL 320
Cdd:cd00609 305 LERLLLEAGVVV---RPGSAFGegGEGFV 330
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
82-234 |
3.19e-08 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 55.14 E-value: 3.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 82 GMAAIYSTFATLLNAGDHIVscqsvfgsthtLFTKYFPKWNIETTYFKAE--------------DSENVEKYIKPNTKIL 147
Cdd:COG0436 99 AKEALALALLALLNPGDEVL-----------VPDPGYPSYRAAVRLAGGKpvpvpldeengflpDPEALEAAITPRTKAI 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 148 YLETPTNPAIEILDLEFF---GQIAKKHNLIFIVDNCF---------ATPYLQQPikyGAD---IVVHSATK--LIDGQg 210
Cdd:COG0436 168 VLNSPNNPTGAVYSREELealAELAREHDLLVISDEIYeelvydgaeHVSILSLP---GLKdrtIVINSFSKsyAMTGW- 243
|
170 180
....*....|....*....|....
gi 1160601572 211 RVlgGVAVGREDLIREIYLFARNT 234
Cdd:COG0436 244 RI--GYAVGPPELIAALLKLQSNL 265
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
59-218 |
8.53e-08 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 51.61 E-value: 8.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 59 NVTEFTDKIVKM--EGAEAGYAFATGMAAIYSTFATLLNAGDHIVSCQSVFGSTHTLFT-------KYFPKWNieTTYFK 129
Cdd:cd01494 1 KLEELEEKLARLlqPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWVAAelagakpVPVPVDD--AGYGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 130 AEDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQIAKKHNLIFIVDNC---FATPYLQQPIKYG-ADIVVHSATKL 205
Cdd:cd01494 79 LDVAILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAAsagGASPAPGVLIPEGgADVVTFSLHKN 158
|
170
....*....|...
gi 1160601572 206 IDGQGrvLGGVAV 218
Cdd:cd01494 159 LGGEG--GGVVIV 169
|
|
| YnbB |
COG4100 |
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion ... |
72-224 |
5.58e-07 |
|
Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 443276 Cd Length: 409 Bit Score: 51.26 E-value: 5.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 72 GAEAG---YAFATGMAAIYSTFATLLNAGDHIVSC--------QSVFG----STHTLftkyfpK-WNIetTY----FKAE 131
Cdd:COG4100 71 GAEDAlvrPQIVSGTHAIALALFGVLRPGDELLSItgkpydtlEEVIGirgeGQGSL------KeFGI--SYrqvpLTED 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 132 ---DSENVEKYIKPNTKILYLETPT----NPAIEILDLEFFGQIAKKHN--LIFIVDNCfatpY-----LQQPIKYGADI 197
Cdd:COG4100 143 gkiDLEAIKKAINEKTKMVLIQRSRgyswRPSLTIEEIGEIIKFVKSINpdVICFVDNC----YgefveTREPTEVGADL 218
|
170 180 190
....*....|....*....|....*....|...
gi 1160601572 198 VVHSatkLIDGQGrvlGGVA------VGREDLI 224
Cdd:COG4100 219 MAGS---LIKNPG---GGLAptggyiAGRKDLV 245
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
45-243 |
2.21e-06 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 49.35 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 45 EEKSKNLYSRFS---NPNvtefTDKIVKMEGAEAgyaFATGMAAIystfatlLNAGDHIVSCQSVFGSTHTLFT----KY 117
Cdd:PRK07682 64 QEIAKYLKKRFAvsyDPN----DEIIVTVGASQA---LDVAMRAI-------INPGDEVLIVEPSFVSYAPLVTlaggVP 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 118 FPKWNIETTYFKAeDSENVEKYIKPNTKILYLETPTNPAIEIL---DLEFFGQIAKKHNLIFIVDNCFAT-PYLQQPIKY 193
Cdd:PRK07682 130 VPVATTLENEFKV-QPAQIEAAITAKTKAILLCSPNNPTGAVLnksELEEIAVIVEKHDLIVLSDEIYAElTYDEAYTSF 208
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1160601572 194 GADIVVHSATKLIDG-------QGRVLGGVAVGRE--DLIREIYLFARNTGPAMSPFNA 243
Cdd:PRK07682 209 ASIKGMRERTILISGfskgfamTGWRLGFIAAPVYfsEAMLKIHQYSMMCAPTMAQFAA 267
|
|
| SelA |
COG1921 |
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis]; |
158-229 |
2.97e-06 |
|
Seryl-tRNA(Sec) selenium transferase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441524 Cd Length: 399 Bit Score: 48.96 E-value: 2.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 158 EILDLEFFGQIAKKHNLIFIVD------------NCFATPYLQQPIKYGADIVVHSATKLIDG-QgrvlGGVAVGREDLI 224
Cdd:COG1921 173 EEVSLAELAELAHEHGLPVIVDlgsgslvdlskyGLPHEPTVQEYLAAGADLVTFSGDKLLGGpQ----AGIIVGKKELI 248
|
....*
gi 1160601572 225 REIYL 229
Cdd:COG1921 249 ERIKK 253
|
|
| PucG |
COG0075 |
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ... |
80-179 |
1.78e-05 |
|
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439845 [Multi-domain] Cd Length: 376 Bit Score: 46.24 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 80 ATGMAAIYSTFATLLNAGDHIVSCQS-VFGsthTLFTKYFPKWNIETTYFKAE-----DSENVEKYIK--PNTKILYL-- 149
Cdd:COG0075 57 GSGTGAMEAALANLVSPGDKVLVLVNgAFG---ERWAEIAERYGAEVVVLEVPwgeavDPEEVEEALAadPDIKAVAVvh 133
|
90 100 110
....*....|....*....|....*....|....
gi 1160601572 150 -ETPT---NPAIEIldleffGQIAKKHNLIFIVD 179
Cdd:COG0075 134 nETSTgvlNPLEEI------GALAKEHGALLIVD 161
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
132-224 |
1.06e-04 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 43.77 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 132 DSENVEKYIKPNTKILYLeTPTNPAI-EILDLEFFGQIAKKHNLIFIVDncFATPYLQQPI---KYGADIVVHSATKLid 207
Cdd:pfam00266 128 DLDELEKLITPKTKLVAI-THVSNVTgTIQPVPEIGKLAHQYGALVLVD--AAQAIGHRPIdvqKLGVDFLAFSGHKL-- 202
|
90 100
....*....|....*....|.
gi 1160601572 208 gqgrvLG----GVAVGREDLI 224
Cdd:pfam00266 203 -----YGptgiGVLYGRRDLL 218
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
84-179 |
2.41e-04 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 42.68 E-value: 2.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 84 AAIYSTFATLLNAGDHIVSCQSVFGSTHTLFtkyfpKWN-IETTYFKAEDSEN-------VEKYIKPNTKILYLETPTNP 155
Cdd:pfam00155 74 ANIEALIFLLANPGDAILVPAPTYASYIRIA-----RLAgGEVVRYPLYDSNDfhldfdaLEAALKEKPKVVLHTSPHNP 148
|
90 100
....*....|....*....|....*..
gi 1160601572 156 AIEILDLEFF---GQIAKKHNLIFIVD 179
Cdd:pfam00155 149 TGTVATLEELeklLDLAKEHNILLLVD 175
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
132-225 |
3.47e-04 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 42.33 E-value: 3.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 132 DSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQ---IAKKHNLIFIVDNCFAT-PYLQQPIKY----GADIV---VH 200
Cdd:PRK06290 168 DLDSIPKDIKEKAKLLYLNYPNNPTGAVATKEFYEEvvdFAKENNIIVVQDAAYAAlTFDGKPLSFlsvpGAKEVgveIH 247
|
90 100
....*....|....*....|....*
gi 1160601572 201 SATKLIDGQGRVLGGVaVGREDLIR 225
Cdd:PRK06290 248 SLSKAYNMTGWRLAFV-VGNELIVK 271
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
132-227 |
4.83e-04 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 42.05 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 132 DSENVEKYIKPNTKILYLETPTnpaieildleFFGQI---------AKKHNLIFIVdncFATP----YLQQPIKYGADIV 198
Cdd:PRK00451 193 DLEALEAAVDDDTAAVVVQYPN----------FFGVIedleeiaeiAHAGGALFIV---GVDPvslgLLKPPGEYGADIV 259
|
90 100 110
....*....|....*....|....*....|....*....
gi 1160601572 199 VhsatklidGQGRVLG------GVAVG----REDLIREI 227
Cdd:PRK00451 260 V--------GEGQPLGiplsfgGPYLGffatRKKLVRQM 290
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
134-224 |
7.01e-04 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 41.23 E-value: 7.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 134 ENVEKYIK---PNTKILYLETPTNPAIEILDLEFFGQ---IAKKHNlIFIV------DNCF----ATPYLQQPikyGA-D 196
Cdd:PRK08175 152 NELERAIResyPKPKMMILGFPSNPTAQCVELEFFEKvvaLAKRYD-VLVVhdlayaDIVYdgwkAPSIMQVP---GAkD 227
|
90 100 110
....*....|....*....|....*....|.
gi 1160601572 197 IVV--HSATKLIDGQG-RVlgGVAVGREDLI 224
Cdd:PRK08175 228 VAVefFTLSKSYNMAGwRI--GFMVGNPELV 256
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
115-234 |
1.69e-03 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 40.17 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 115 TKYFPKWNIETTYFKaeDSENVEKYIKPNTKILYLETPTNPAIEILDLEFFGQI---AKKHNLIFIVDNCFATPYL--QQ 189
Cdd:PRK07681 140 TSYYMPLKKENDFLP--DLELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEViafAKKHNIIVVHDFAYAEFYFdgNK 217
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1160601572 190 PIKY----GAD---IVVHSATKLIDGQG-RVlgGVAVGREDLIREIYLFARNT 234
Cdd:PRK07681 218 PISFlsvpGAKevgVEINSLSKSYSLAGsRI--GYMIGNEEIVRALTQFKSNT 268
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
80-179 |
2.53e-03 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 39.54 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 80 ATG--MAAIYstfaTLLNAGDHIVScqsVFGSTHTLFTkyFPK--------WNIETTYFKAEDSENVEKYIKPNTKILYL 149
Cdd:PRK07324 89 ATGanFLVLY----ALVEPGDHVIS---VYPTYQQLYD--IPEslgaevdyWQLKEENGWLPDLDELRRLVRPNTKLICI 159
|
90 100 110
....*....|....*....|....*....|...
gi 1160601572 150 ETPTNPAIEILDLEFFGQ---IAKKHNLIFIVD 179
Cdd:PRK07324 160 NNANNPTGALMDRAYLEEiveIARSVDAYVLSD 192
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
142-224 |
3.18e-03 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 39.28 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 142 PNTKILYLETPTNPAIEILDLEFFGQI---AKKHNLIFIVDNCFATPY---------LQQPikyGA-DIVVH--SATKLI 206
Cdd:PRK09148 164 PKPIALIVNYPSNPTAYVADLDFYKDVvafAKKHDIIILSDLAYSEIYfdgnpppsvLQVP---GAkDVTVEftSMSKTF 240
|
90
....*....|....*....
gi 1160601572 207 DGQG-RVlgGVAVGREDLI 224
Cdd:PRK09148 241 SMAGwRM--GFAVGNERLI 257
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
121-283 |
3.33e-03 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 39.28 E-value: 3.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 121 WNIettyfkaeDSENVEKYIKPNTK-ILyletPT----NPAieilDLEFFGQIAKKHNLIFIVDNC--FATPYLQQPIky 193
Cdd:COG0399 104 YNI--------DPEALEAAITPRTKaII----PVhlygQPA----DMDAIMAIAKKHGLKVIEDAAqaLGATYKGKKV-- 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 194 G--ADIVVHS--ATKLI---DGqgrvlGGVAVGREDLIREIYLFaRNTGPA---------------MSPFNAWVLSKSLE 251
Cdd:COG0399 166 GtfGDAGCFSfyPTKNLttgEG-----GAVVTNDEELAERARSL-RNHGRDrdakyehvelgynyrMDELQAAIGLAQLK 239
|
170 180 190
....*....|....*....|....*....|..
gi 1160601572 252 TLAIRVEKHCENALKVAEFLESHPNVELTKYP 283
Cdd:COG0399 240 RLDEFIARRRAIAARYREALADLPGLTLPKVP 271
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
145-225 |
5.17e-03 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 38.55 E-value: 5.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 145 KILYLETPTNPAIEILDLEFFGQI---AKKHNLIFIVDNCFA---------TPYLQQPikyGA-DIVV--HSATKLIDGQ 209
Cdd:PRK05942 172 KILYFNYPSNPTTATAPREFFEEIvafARKYEIMLVHDLCYAelafdgyqpTSLLEIP---GAkDIGVefHTLSKTYNMA 248
|
90
....*....|....*..
gi 1160601572 210 G-RVlgGVAVGREDLIR 225
Cdd:PRK05942 249 GwRV--GFVVGNRHIIQ 263
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
85-179 |
6.24e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 38.29 E-value: 6.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1160601572 85 AIYSTFATLLNAGDHIVSCQSvFGSTHTLFTKYFpkwNIE----TTY----FKAEDSENVEKYIKPNTKILYLETPTNPA 156
Cdd:PRK07568 100 AILFAMMAICDPGDEILVPEP-FYANYNGFATSA---GVKivpvTTKieegFHLPSKEEIEKLITPKTKAILISNPGNPT 175
|
90 100
....*....|....*....|....*.
gi 1160601572 157 IEIL---DLEFFGQIAKKHNLIFIVD 179
Cdd:PRK07568 176 GVVYtkeELEMLAEIAKKHDLFLISD 201
|
|
| |
