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Conserved domains on  [gi|115494899|ref|YP_778680|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Rusa unicolor swinhoei]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-175 1.23e-95

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 274.37  E-value: 1.23e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   1 MMTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  81 EIWVSNKTVLGAFVTGLLMEVMMVYYVLKDEEVEIVFQFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160
                        170
                 ....*....|....*
gi 115494899 161 LLIGVVVIMEITRGN 175
Cdd:MTH00109 161 LFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-175 1.23e-95

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 274.37  E-value: 1.23e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   1 MMTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  81 EIWVSNKTVLGAFVTGLLMEVMMVYYVLKDEEVEIVFQFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160
                        170
                 ....*....|....*
gi 115494899 161 LLIGVVVIMEITRGN 175
Cdd:MTH00109 161 LFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 1.14e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 64.45  E-value: 1.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   18 VGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPEIWVSNKTVLGAFVTGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 115494899   98 LMEVMMVYYVLKDEEVEIVfqfnglgdwviyDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLLIGVVVIMEI 171
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAA------------AAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-175 1.23e-95

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 274.37  E-value: 1.23e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   1 MMTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  81 EIWVSNKTVLGAFVTGLLMEVMMVYYVLKDEEVEIVFQFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160
                        170
                 ....*....|....*
gi 115494899 161 LLIGVVVIMEITRGN 175
Cdd:MTH00109 161 LFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
2-174 1.47e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 124.48  E-value: 1.47e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   2 MTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  82 IWVSNkTVLGAFVTGLLMEVMMVYYVLKDEEVeivfqfnglGDWVI-YDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00138  81 SWGSW-SVLGYVVGYLVGVVLAAGLFWGGWYE---------GSWVVvDELKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150
                        170
                 ....*....|....
gi 115494899 161 LLIGVVVIMEITRG 174
Cdd:MTH00138 151 LLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
2-174 1.01e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 109.55  E-value: 1.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   2 MTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  82 IWVSNKTVLGAFVTGLlmeVMMVYYVLKDEEVEIVFQFNGLGDWViydtgdsGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00065  81 AWGSWSVLVYVLFYLL---LLIVGYILFGCNFSLEFLFTNYDTEF-------SVVGYDWGGVGLMYSSGGWFLMISGWVL 150
                        170
                 ....*....|...
gi 115494899 162 LIGVVVIMEITRG 174
Cdd:MTH00065 151 LLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
2-174 1.30e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 96.36  E-value: 1.30e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   2 MTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  82 IWVSNKTVLGAFVTGLLMEVMMVYYVlkdeeveiVFQFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVG--------GLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152
                        170
                 ....*....|...
gi 115494899 162 LIGVVVIMEITRG 174
Cdd:MTH00115 153 LLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
2-174 6.31e-17

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 73.87  E-value: 6.31e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   2 MTYIVFILSIMFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  82 IWVSNKTVLGAFVTGLLMEVMMVYYvlkdeeveivfqfnGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYF--------------YGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVL 146
                        170
                 ....*....|...
gi 115494899 162 LIGVVVIMEITRG 174
Cdd:MTH00214 147 FLVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
1-175 8.60e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 65.31  E-value: 8.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   1 MMTYIVFILsIMFVLGFVGFSSkpSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00045   1 MVFYLFLIL-MLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899  81 EIWVSNKTVLGAFVTGLLmevmmvyyvlkdeeveIVFQFNGLGDWVIYDTGDSGFFSEeaMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00045  78 SVSNLGEVLVLSLLLSLW----------------VFISFDNFLELSNNNWSLVSLSDL--VGSSELYNSGGLYLLLGGFI 139
                        170
                 ....*....|....*
gi 115494899 161 LLIGVVVIMEITRGN 175
Cdd:MTH00045 140 LLVALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 1.14e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 64.45  E-value: 1.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   18 VGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPEIWVSNKTVLGAFVTGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 115494899   98 LMEVMMVYYVLKDEEVEIVfqfnglgdwviyDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLLIGVVVIMEI 171
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAA------------AAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
8-112 7.67e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 38.06  E-value: 7.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   8 ILSIMFVLGFVgFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMAteqyPEIWVSNK 87
Cdd:MTH00212   6 LLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS----PNEHLFFK 80
                         90       100
                 ....*....|....*....|....*
gi 115494899  88 TVLGAFVTGLLMEVMMVYYVLKDEE 112
Cdd:MTH00212  81 KYFKGFGMILISLNLYLLLMTLGSS 105
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
1-128 1.24e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 37.56  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115494899   1 MMTYIVFILSIMFVLGFVGFSSkpsPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATeQYP 80
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSKQ---PLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSP-NPL 76
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 115494899  81 EIWVSNKTVLGAFVTGLLMEVMMVYYVLKDEEVEIVFQFNGLGDWVIY 128
Cdd:MTH00152  77 FGSNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSLFDGSSGSLSF 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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