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Conserved domains on  [gi|11545720|ref|NP_071464|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Sardinops melanostictus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-171 1.92e-57

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 177.64  E-value: 1.92e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    3 FQYIWLAGFVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPEGTL 82
Cdd:MTH00138   4 LMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   83 EAAPYEFLILVVLGISLLVAQSWRTCYNFAVGGFNNLKEFLMAPTDTSGVSMLYSFGGVMVVVCALALLVTLFVVLELTR 162
Cdd:MTH00138  84 SWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTR 163


                 ....*....
gi 11545720  163 GSARGALRA 171
Cdd:MTH00138 164 GLSRGALRA 172
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-171 1.92e-57

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 177.64  E-value: 1.92e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    3 FQYIWLAGFVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPEGTL 82
Cdd:MTH00138   4 LMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   83 EAAPYEFLILVVLGISLLVAQSWRTCYNFAVGGFNNLKEFLMAPTDTSGVSMLYSFGGVMVVVCALALLVTLFVVLELTR 162
Cdd:MTH00138  84 SWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTR 163


                 ....*....
gi 11545720  163 GSARGALRA 171
Cdd:MTH00138 164 GLSRGALRA 172
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
16-160 1.78e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.78e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    16 IGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAAL-AADPFPEGTLEAAPYEFLILVV 94
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 11545720    95 LGISLLVAQSWRTCYNFAVGGFNNlkefLMAPTDTSGVSMLYSFgGVMVVVCALALLVTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAP----DVGNIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 3-171 1.92e-57

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 177.64  E-value: 1.92e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    3 FQYIWLAGFVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPEGTL 82
Cdd:MTH00138   4 LMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   83 EAAPYEFLILVVLGISLLVAQSWRTCYNFAVGGFNNLKEFLMAPTDTSGVSMLYSFGGVMVVVCALALLVTLFVVLELTR 162
Cdd:MTH00138  84 SWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTR 163


                 ....*....
gi 11545720  163 GSARGALRA 171
Cdd:MTH00138 164 GLSRGALRA 172
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 8-171 4.00e-44

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 143.45  E-value: 4.00e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    8 LAGFVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPE--GTLEAA 85
Cdd:MTH00065   9 MLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEawGSWSVL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   86 PYEFLILVVLGISLLVAQSWrTCYNFAVGGFNnlKEFLMAPTDTSGVSMLYSFGGVMVVVCALALLVTLFVVLELTRGSA 165
Cdd:MTH00065  89 VYVLFYLLLLIVGYILFGCN-FSLEFLFTNYD--TEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEVTRGLS 165


                 ....*.
gi 11545720  166 RGALRA 171
Cdd:MTH00065 166 RGSLRA 171
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-171 1.36e-38

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 129.48  E-value: 1.36e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    1 MSFQYIWLAGFVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPE- 79
Cdd:MTH00115   2 MYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPEa 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   80 -GTLEAAPYEFLILVVLGISLLVAQSWRTCYNFAVGGFNNLKEFLMApTDTSGVSMLYSFGGVMVVVCALALLVTLFVVL 158
Cdd:MTH00115  82 wGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVR-LDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|...
gi 11545720  159 ELTRGSARGALRA 171
Cdd:MTH00115 161 ELVRGLSRGALRA 173
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-171 1.36e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 93.51  E-value: 1.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    1 MSFQYIWLAGFVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPEG 80
Cdd:MTH00214   2 LYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPES 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   81 TLEAAPYEFLILVVLGISLLVAQSWRTCYNFAVGGFNNLKEFLMaptdtSGVSMLYSFGGVMVVVCALALLVTLFVVLEL 160
Cdd:MTH00214  82 WGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                        170
                 ....*....|.
gi 11545720  161 TRGSARGALRA 171
Cdd:MTH00214 157 VRGLSRGALRV 167
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 11-163 6.89e-21

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 84.08  E-value: 6.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   11 FVIGVIGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPegtlEAAPYEFL 90
Cdd:MTH00109  13 FVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP----ETWVSNKV 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   91 ILVVLGISLLVAQSWrTCYNFA------VGGFNNLKEFLMAPT--------DTSGVSMLYSFGGVMVVVCALALLVTLFV 156
Cdd:MTH00109  89 VLGALLLGLLMELLL-VLYVLKddevevVFNFNGLGDWVIYDTggsgffseDAMGVAALYSYGTWLVVVTGWSLFIGVFV 167


                 ....*..
gi 11545720  157 VLELTRG 163
Cdd:MTH00109 168 IIEITRG 174
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 23-171 2.16e-19

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 79.95  E-value: 2.16e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   23 SPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPE-GTLEAAPYEFLILVVLGISLLV 101
Cdd:MTH00045  22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSvSNLGEVLVLSLLLSLWVFISFD 101

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720  102 AQSWRTCYNFAVGGFNNLkeflmaptdtSGVSMLYSFGGVMVVVCALALLVTLFVVLELTRGSARGALRA 171
Cdd:MTH00045 102 NFLELSNNNWSLVSLSDL----------VGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
16-160 1.78e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.78e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720    16 IGIMTNPSPYFAALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAAL-AADPFPEGTLEAAPYEFLILVV 94
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 11545720    95 LGISLLVAQSWRTCYNFAVGGFNNlkefLMAPTDTSGVSMLYSFgGVMVVVCALALLVTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAP----DVGNIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 28-157 1.70e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 37.17  E-value: 1.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 11545720   28 ALGLVMCSAATCCILVFGGSTFLAVVLFLIYLGGMLVVFAFTAALAADPFPEGTLEAAPYEFLILVVLGISLLVAQSWRT 107
Cdd:MTH00152  27 GLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGSNFKFVFFSLTLFGFLGLFFFFLYLYSS 106

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 11545720  108 CYNFAVGGFNNLKEFLMaptdtSGVSMLYSFGGVMVVVCALALLVTLFVV 157
Cdd:MTH00152 107 GGLSLSSLFDGSSGSLS-----FGGGLYSSSGWSIFVFLAVLLLIVMVSV 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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