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Conserved domains on  [gi|115311936|sp|Q1GCR3|]
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RecName: Full=Undecaprenyl-diphosphatase; AltName: Full=Bacitracin resistance protein; AltName: Full=Undecaprenyl pyrophosphate phosphatase

Protein Classification

UppP family protein( domain architecture ID 10005023)

UppP family protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UppP COG1968
Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];
1-266 9.93e-80

Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];


:

Pssm-ID: 441571  Cd Length: 265  Bit Score: 241.10  E-value: 9.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   1 MPLLQLILVALIQGVTEFLPVSSSGHLILLPRLTGLE-DQGQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRALigRLD 79
Cdd:COG1968    1 MDLLQAIILGIVQGLTEFLPVSSSGHLILVPALLGWEgDPGLAFDVVIQLGTLLAVLVYFRKDILRLLRGLFRSL--RRD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  80 TKGARLALGLIVATIPTVIFGTFLYFTgLSESLRSVAVIGWTMLVFGVVLYIADQRGPIDKSASDWGVRDAVIMGLWQML 159
Cdd:COG1968   79 DPDARLALLIIVATIPAAIIGLLFKDF-IESLLRSPLVVAIALIVGGLLLLLAERLGRRKRTLEDLTLKDALLIGLAQAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936 160 ALIPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMM 239
Cdd:COG1968  158 ALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLKLLKALSSVDLGPLLVGFVVAFVVAYLAIKWLL 237
                        250       260
                 ....*....|....*....|....*..
gi 115311936 240 RLLRSVSFTPYVIYRVALGMVLLFIAY 266
Cdd:COG1968  238 RYLKRHSFKPFAIYRIILGIVLLILLL 264
 
Name Accession Description Interval E-value
UppP COG1968
Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];
1-266 9.93e-80

Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];


Pssm-ID: 441571  Cd Length: 265  Bit Score: 241.10  E-value: 9.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   1 MPLLQLILVALIQGVTEFLPVSSSGHLILLPRLTGLE-DQGQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRALigRLD 79
Cdd:COG1968    1 MDLLQAIILGIVQGLTEFLPVSSSGHLILVPALLGWEgDPGLAFDVVIQLGTLLAVLVYFRKDILRLLRGLFRSL--RRD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  80 TKGARLALGLIVATIPTVIFGTFLYFTgLSESLRSVAVIGWTMLVFGVVLYIADQRGPIDKSASDWGVRDAVIMGLWQML 159
Cdd:COG1968   79 DPDARLALLIIVATIPAAIIGLLFKDF-IESLLRSPLVVAIALIVGGLLLLLAERLGRRKRTLEDLTLKDALLIGLAQAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936 160 ALIPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMM 239
Cdd:COG1968  158 ALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLKLLKALSSVDLGPLLVGFVVAFVVAYLAIKWLL 237
                        250       260
                 ....*....|....*....|....*..
gi 115311936 240 RLLRSVSFTPYVIYRVALGMVLLFIAY 266
Cdd:COG1968  238 RYLKRHSFKPFAIYRIILGIVLLILLL 264
PRK00281 PRK00281
undecaprenyl-diphosphate phosphatase;
1-266 6.56e-72

undecaprenyl-diphosphate phosphatase;


Pssm-ID: 234712  Cd Length: 268  Bit Score: 221.52  E-value: 6.56e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   1 MPLLQLILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQ-GQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRAliGRLD 79
Cdd:PRK00281   3 MDLLKAIILGIVEGLTEFLPISSTGHLILVGHLLGFEDDfGKTFDVVIQLGAILAVVVYFRRRLWRLLGGSGKG--GRGD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  80 TKGARLALGLIVATIPTVIFGTFLYfTGLSESLRSVAVIGWTMLVFGVVLYIADQR-GPIDKSASDWGVRDAVIMGLWQM 158
Cdd:PRK00281  81 REDRRLLLLVIVATIPAGVLGLLFK-DFIKEHLFSPIVVAIALIVGGILLLWAEKRkGPRVRSLDDLTYKDALLIGLAQC 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936 159 LALIPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALM 238
Cdd:PRK00281 160 LALIPGTSRSGATISGGLLLGLSREAAAEFSFLLAIPAMLGASLLDLLKLFHLLSAADLPLLAVGFVVAFVVALIAIKWL 239
                        250       260
                 ....*....|....*....|....*...
gi 115311936 239 MRLLRSVSFTPYVIYRVALGMVLLFIAY 266
Cdd:PRK00281 240 LKYIKRHSFTPFAIYRIILGALLLILLF 267
BacA pfam02673
Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative ...
7-260 1.17e-63

Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteriztic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.


Pssm-ID: 460646  Cd Length: 259  Bit Score: 199.99  E-value: 1.17e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936    7 ILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQGQAI---DVAVHVGTLAAVVLFFWRDVRAGLIGLPRALIGR-LDTKG 82
Cdd:pfam02673   2 IILGIVQGLTEFLPVSSSGHLILVPHLLGFGWEDPGLaafDVVIHLGTILAVLVYFRKDIWRLLKGFFRSLKKRfADDPD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   83 ARLALGLIVATIPTVIFGtFLYFTGLSESLRSVAVIGWTMLVFGVVLYIADQRGPI-DKSASDWGVRDAVIMGLWQMLAL 161
Cdd:pfam02673  82 RRLAWLIIVATIPAGILG-LLLKDFIEALLRSPLVVAIALIVTGLLLLLAERLGKRkRKSLDDLTLKDALIIGLAQALAL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  162 IPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMMRL 241
Cdd:pfam02673 161 IPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLLKSGSGLLTGDLALLVGFVVAFVVGYLAIKFLLRY 240
                         250
                  ....*....|....*....
gi 115311936  242 LRSVSFTPYVIYRVALGMV 260
Cdd:pfam02673 241 VKKHSLKPFAIYRIILGIL 259
undec_PP_bacA TIGR00753
undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. ...
7-258 1.21e-38

undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. Overexpression of this protein in Escherichia coli is associated with bacitracin resistance, and the protein was originally proposed to be an undecaprenol kinase and called bacA. It is now known to be an undecaprenyl pyrophosphate phosphatase (EC 3.6.1.27) and is renamed UppP. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 129836  Cd Length: 255  Bit Score: 135.59  E-value: 1.21e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936    7 ILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQGQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRALIGRLDTKGARLA 86
Cdd:TIGR00753   2 IILGIVQGLTEFLPISSTGHLIIVRHILGSGDAGKSFTIVIQLGSILAVVIYFWRRILRLLGIWIRFSTRKTESSDLLLL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   87 LGLIVATIPTVIFGTFLYFTGLSESLRSVAVIGWTMLVFGVVLYIADQ--RGPIDKSASDWGVRDAVIMGLWQMLALIPG 164
Cdd:TIGR00753  82 KLILLGLIPTVVLGLLFKDLIKSLLFNFLLTVVIALIVGAGLLILAEEvnRQTLKRDFERLTLRDAIMMGLFQCLALIPG 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  165 TSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMMRLLRS 244
Cdd:TIGR00753 162 VSRSGSTISGGLFIGLNRKAAAEFSFLLAIPIMFGAGLLSLKKSWDSFTSGDFPELIVGFITAFVVALFAIAWFLKFLNK 241
                         250
                  ....*....|....
gi 115311936  245 VSFTPYVIYRVALG 258
Cdd:TIGR00753 242 HSLYIFVIYRFILG 255
 
Name Accession Description Interval E-value
UppP COG1968
Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];
1-266 9.93e-80

Undecaprenyl pyrophosphate phosphatase [Lipid transport and metabolism];


Pssm-ID: 441571  Cd Length: 265  Bit Score: 241.10  E-value: 9.93e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   1 MPLLQLILVALIQGVTEFLPVSSSGHLILLPRLTGLE-DQGQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRALigRLD 79
Cdd:COG1968    1 MDLLQAIILGIVQGLTEFLPVSSSGHLILVPALLGWEgDPGLAFDVVIQLGTLLAVLVYFRKDILRLLRGLFRSL--RRD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  80 TKGARLALGLIVATIPTVIFGTFLYFTgLSESLRSVAVIGWTMLVFGVVLYIADQRGPIDKSASDWGVRDAVIMGLWQML 159
Cdd:COG1968   79 DPDARLALLIIVATIPAAIIGLLFKDF-IESLLRSPLVVAIALIVGGLLLLLAERLGRRKRTLEDLTLKDALLIGLAQAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936 160 ALIPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMM 239
Cdd:COG1968  158 ALIPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLKLLKALSSVDLGPLLVGFVVAFVVAYLAIKWLL 237
                        250       260
                 ....*....|....*....|....*..
gi 115311936 240 RLLRSVSFTPYVIYRVALGMVLLFIAY 266
Cdd:COG1968  238 RYLKRHSFKPFAIYRIILGIVLLILLL 264
PRK00281 PRK00281
undecaprenyl-diphosphate phosphatase;
1-266 6.56e-72

undecaprenyl-diphosphate phosphatase;


Pssm-ID: 234712  Cd Length: 268  Bit Score: 221.52  E-value: 6.56e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   1 MPLLQLILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQ-GQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRAliGRLD 79
Cdd:PRK00281   3 MDLLKAIILGIVEGLTEFLPISSTGHLILVGHLLGFEDDfGKTFDVVIQLGAILAVVVYFRRRLWRLLGGSGKG--GRGD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  80 TKGARLALGLIVATIPTVIFGTFLYfTGLSESLRSVAVIGWTMLVFGVVLYIADQR-GPIDKSASDWGVRDAVIMGLWQM 158
Cdd:PRK00281  81 REDRRLLLLVIVATIPAGVLGLLFK-DFIKEHLFSPIVVAIALIVGGILLLWAEKRkGPRVRSLDDLTYKDALLIGLAQC 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936 159 LALIPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALM 238
Cdd:PRK00281 160 LALIPGTSRSGATISGGLLLGLSREAAAEFSFLLAIPAMLGASLLDLLKLFHLLSAADLPLLAVGFVVAFVVALIAIKWL 239
                        250       260
                 ....*....|....*....|....*...
gi 115311936 239 MRLLRSVSFTPYVIYRVALGMVLLFIAY 266
Cdd:PRK00281 240 LKYIKRHSFTPFAIYRIILGALLLILLF 267
BacA pfam02673
Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative ...
7-260 1.17e-63

Bacitracin resistance protein BacA; Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteriztic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.


Pssm-ID: 460646  Cd Length: 259  Bit Score: 199.99  E-value: 1.17e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936    7 ILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQGQAI---DVAVHVGTLAAVVLFFWRDVRAGLIGLPRALIGR-LDTKG 82
Cdd:pfam02673   2 IILGIVQGLTEFLPVSSSGHLILVPHLLGFGWEDPGLaafDVVIHLGTILAVLVYFRKDIWRLLKGFFRSLKKRfADDPD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   83 ARLALGLIVATIPTVIFGtFLYFTGLSESLRSVAVIGWTMLVFGVVLYIADQRGPI-DKSASDWGVRDAVIMGLWQMLAL 161
Cdd:pfam02673  82 RRLAWLIIVATIPAGILG-LLLKDFIEALLRSPLVVAIALIVTGLLLLLAERLGKRkRKSLDDLTLKDALIIGLAQALAL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  162 IPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMMRL 241
Cdd:pfam02673 161 IPGVSRSGATITGGLLLGLSREAAARFSFLLAIPAILGAGLLELLLKSGSGLLTGDLALLVGFVVAFVVGYLAIKFLLRY 240
                         250
                  ....*....|....*....
gi 115311936  242 LRSVSFTPYVIYRVALGMV 260
Cdd:pfam02673 241 VKKHSLKPFAIYRIILGIL 259
PRK12554 PRK12554
undecaprenyl pyrophosphate phosphatase; Reviewed
1-262 8.39e-57

undecaprenyl pyrophosphate phosphatase; Reviewed


Pssm-ID: 237134  Cd Length: 276  Bit Score: 183.10  E-value: 8.39e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   1 MPLLQLILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQGQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRALIGR--L 78
Cdd:PRK12554   1 MSLFKAIILGLVQGLTEFLPVSSSGHLRIVGALLGWDDPGAAFTAIIQLGTLLAVLLYFRKDIIRIIKNFFSSLFGRkpK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  79 DTKGARLALGLIVATIPTVIFGtFLYFTGLSESLRSVAVIGWTMLVFGVVLYIADQRGPI--DKSASDWGVRDAVIMGLW 156
Cdd:PRK12554  81 AKSDARFGWYIIIGTIPAGVLG-LLFKDRIETVLRDLRIVAIALIVTGVLLWLADNLARNrgRKSDEDLTWKDAIIIGLA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936 157 QMLALIPGTSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVD-LMRDMGIAALLAMASALAAL 235
Cdd:PRK12554 160 QALALIPGVSRSGATIIAGLLLGLTREAAARFSFLLAIPAVFGAGLLELYKIFHDPNAStLLGPTAVAFIVAFIVGYISI 239
                        250       260
                 ....*....|....*....|....*..
gi 115311936 236 ALMMRLLRSVSFTPYVIYRVALGMVLL 262
Cdd:PRK12554 240 AWFMNFLKKGSLKYFAIYRIILGVLLL 266
undec_PP_bacA TIGR00753
undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. ...
7-258 1.21e-38

undecaprenyl-diphosphatase UppP; This is a family of small, highly hydrophobic proteins. Overexpression of this protein in Escherichia coli is associated with bacitracin resistance, and the protein was originally proposed to be an undecaprenol kinase and called bacA. It is now known to be an undecaprenyl pyrophosphate phosphatase (EC 3.6.1.27) and is renamed UppP. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 129836  Cd Length: 255  Bit Score: 135.59  E-value: 1.21e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936    7 ILVALIQGVTEFLPVSSSGHLILLPRLTGLEDQGQAIDVAVHVGTLAAVVLFFWRDVRAGLIGLPRALIGRLDTKGARLA 86
Cdd:TIGR00753   2 IILGIVQGLTEFLPISSTGHLIIVRHILGSGDAGKSFTIVIQLGSILAVVIYFWRRILRLLGIWIRFSTRKTESSDLLLL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936   87 LGLIVATIPTVIFGTFLYFTGLSESLRSVAVIGWTMLVFGVVLYIADQ--RGPIDKSASDWGVRDAVIMGLWQMLALIPG 164
Cdd:TIGR00753  82 KLILLGLIPTVVLGLLFKDLIKSLLFNFLLTVVIALIVGAGLLILAEEvnRQTLKRDFERLTLRDAIMMGLFQCLALIPG 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115311936  165 TSRSGITITGARSLGYNREDGARIAMLMSIPTIIASGVLLGTEVALDADVDLMRDMGIAALLAMASALAALALMMRLLRS 244
Cdd:TIGR00753 162 VSRSGSTISGGLFIGLNRKAAAEFSFLLAIPIMFGAGLLSLKKSWDSFTSGDFPELIVGFITAFVVALFAIAWFLKFLNK 241
                         250
                  ....*....|....
gi 115311936  245 VSFTPYVIYRVALG 258
Cdd:TIGR00753 242 HSLYIFVIYRFILG 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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