NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1150150991|ref|YP_009349970|]
View 

NADH dehydrogenase subunit 4L (mitochondrion) [Phyllomimus sinicus]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.71e-17

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 70.18  E-value: 1.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  4 MLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLMLFLSFCVCEGALGLSILVLLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1150150991 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.71e-17

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 70.18  E-value: 1.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  4 MLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLMLFLSFCVCEGALGLSILVLLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1150150991 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
7-98 2.06e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 36.77  E-value: 2.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  7 LLILIFIMLGGIWVFCSnRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEI--YFLMLFLSFCVCEGALGLSILVLLIRT 84
Cdd:pfam00420  3 LLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIYRT 81

                         90
                 ....*....|....
gi 1150150991 85 HGNDYFQSFSILQC 98
Cdd:pfam00420 82 HGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 1.71e-17

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 70.18  E-value: 1.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  4 MLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLMLFLSFCVCEGALGLSILVLLIR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1150150991 84 THGNDYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 8.61e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 51.00  E-value: 8.61e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  3 MMLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLMLFLSFCVCEGALGLSILVLLI 82
Cdd:MTH00149   2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                         90
                 ....*....|....*.
gi 1150150991 83 RTHGNDYFQSFSILQC 98
Cdd:MTH00149  82 RLHGNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 7-98 8.60e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 48.43  E-value: 8.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  7 LLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLMLFLSFCVCEGALGLSILVLLIRTHG 86
Cdd:MTH00188   6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                         90
                 ....*....|..
gi 1150150991 87 NDYFQSFSILQC 98
Cdd:MTH00188  86 SDYVSSLNLIKC 97
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 24-98 1.86e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 47.65  E-value: 1.86e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1150150991 24 NRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFL--MLFLSFCVCEGALGLSILVLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00126  22 HRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 3-98 2.95e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 44.45  E-value: 2.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  3 MMLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLM--LFLSFCVCEGALGLSILVL 80
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVA 80

                         90
                 ....*....|....*...
gi 1150150991 81 LIRTHGNDYFQSFSILQC 98
Cdd:MTH00125  81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 4.01e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 44.21  E-value: 4.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  1 MVMMLNLLILIFIMlgGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFL--MLFLSFCVCEGALGLSIL 78
Cdd:MTH00067   1 MSPTYFTFYSAFLL--GLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALM 78

                         90       100
                 ....*....|....*....|
gi 1150150991 79 VLLIRTHGNDYFQSFSILQC 98
Cdd:MTH00067  79 VATTRTHGTDHLKNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 3-96 3.32e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 38.77  E-value: 3.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  3 MMLNLLILIFIMLGGiwvFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFD--SEIYFLMLFLSFCVCEGALGLSILVL 80
Cdd:MTH00181   1 MMFVFISAFILLLLG---LSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSssSMLMFGLILLTFSACEAVLGLSLLVA 77

                         90
                 ....*....|....*.
gi 1150150991 81 LIRTHGNDYFQSFSIL 96
Cdd:MTH00181  78 TNRTHGSDHLLKFNLL 93
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 3-98 4.21e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 38.76  E-value: 4.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  3 MMLNLLILIFIMLGGIWVFcsnRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIYFLM--LFLSFCVCEGALGLSILVL 80
Cdd:MTH00107   4 IYMNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1150150991 81 LIRTHGNDYFQSFSILQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 3-98 1.16e-04

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 37.81  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  3 MMLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLE-FMVLSMFLLLFVLFNFFDSEIYFLMLFLSFCVCEGALGLSILVLL 81
Cdd:MTH00013   1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEaMILSLALFIPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVLM 80

                         90
                 ....*....|....*..
gi 1150150991 82 IRTHGNDYFQSFSILQC 98
Cdd:MTH00013  81 TRSYGNDMLKSLTSNKC 97
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
7-98 2.06e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 36.77  E-value: 2.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  7 LLILIFIMLGGIWVFCSnRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEI--YFLMLFLSFCVCEGALGLSILVLLIRT 84
Cdd:pfam00420  3 LLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIYRT 81

                         90
                 ....*....|....
gi 1150150991 85 HGNDYFQSFSILQC 98
Cdd:pfam00420 82 HGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 2.34e-03

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 34.12  E-value: 2.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1150150991  3 MMLNLLILIFIMLGGIWVFCSNRSHLLAMLLSLEFMVLSMFLLLFVLFNFFDSEIY--FLMLFLSFCVCEGALGLSILVL 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1150150991 81 LIRTHGNDYFQSFSILQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH