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Conserved domains on  [gi|1149685236|ref|YP_009345878|]
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major capsid protein L1 [Human papillomavirus 156]

Protein Classification

major capsid protein L1( domain architecture ID 10010233)

major capsid protein L1 forms an icosahedral capsid with a 50 nm diameter; the capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-509 0e+00

major capsid L1 protein; Provisional


:

Pssm-ID: 222928  Cd Length: 503  Bit Score: 867.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236   1 MSLWMQTTGKLYLPPQkPVAKVLNTDDFIKRTGYYFHGGTERLLMVGHPYYDVMDTvDDEKVAVPKVSAQQFRVLRLRLP 80
Cdd:PHA02778    1 MALWLPSSGKLYLPPT-PVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDA-DKNKVTVPKVSGNQYRVFRVKLP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236  81 DPNKFAIADEKIFNPEKERLVWRLTGLEIGRGGPLGISPTGHPLFNKYTDTENPNTYPTKQDEnnDYRQDISVDPKQIQM 160
Cdd:PHA02778   79 DPNKFALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGT--DDRQNVSFDPKQTQL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 161 FIVGCTPATGEYWDVTKPCKDRPLNNGDCPPIELFHTYIQDGDMCEFGFGNANFESFQQDRAGVPLELTNETALWPDFLK 240
Cdd:PHA02778  157 FIVGCTPALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLK 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 241 MTKDIYGDQVFFYSKREQLYARHYFAKAGVDGDALPPTSYLNPDDGKPQKdLGPYSYYSTPSGSLVSSDSNMFNRPYWLH 320
Cdd:PHA02778  237 MANDPYGDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAQT-LGSSVYFPTPSGSLVSSDAQLFNRPYWLQ 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 321 RALGANNGILWGNQCFITVVDNTRNINFGLSIYKqqaNMTNEYKYKSGDFRNYLRHVEEYEVEIIVELCKVPLDPDVLAH 400
Cdd:PHA02778  316 RAQGHNNGICWNNQLFVTVVDNTRNTNFTISVKT---DETPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAH 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 401 INVMNPRILDEWELAFVPPPPQGIEDSYRYILSLATKCPADVIPAEKPDPWDKYTFWEIDMTEKLSAELSQFSLGKRFLY 480
Cdd:PHA02778  393 LHTMNPSILEDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLF 472

                         490       500       510
                  ....*....|....*....|....*....|
gi 1149685236 481 QSGLL-KNKRIRDSDDIGETRRSVKRKRRN 509
Cdd:PHA02778  473 QAGLRrRTRRRKRKSTSSSSSRSTKRRRRK 502
 
Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-509 0e+00

major capsid L1 protein; Provisional


Pssm-ID: 222928  Cd Length: 503  Bit Score: 867.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236   1 MSLWMQTTGKLYLPPQkPVAKVLNTDDFIKRTGYYFHGGTERLLMVGHPYYDVMDTvDDEKVAVPKVSAQQFRVLRLRLP 80
Cdd:PHA02778    1 MALWLPSSGKLYLPPT-PVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDA-DKNKVTVPKVSGNQYRVFRVKLP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236  81 DPNKFAIADEKIFNPEKERLVWRLTGLEIGRGGPLGISPTGHPLFNKYTDTENPNTYPTKQDEnnDYRQDISVDPKQIQM 160
Cdd:PHA02778   79 DPNKFALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGT--DDRQNVSFDPKQTQL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 161 FIVGCTPATGEYWDVTKPCKDRPLNNGDCPPIELFHTYIQDGDMCEFGFGNANFESFQQDRAGVPLELTNETALWPDFLK 240
Cdd:PHA02778  157 FIVGCTPALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLK 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 241 MTKDIYGDQVFFYSKREQLYARHYFAKAGVDGDALPPTSYLNPDDGKPQKdLGPYSYYSTPSGSLVSSDSNMFNRPYWLH 320
Cdd:PHA02778  237 MANDPYGDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAQT-LGSSVYFPTPSGSLVSSDAQLFNRPYWLQ 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 321 RALGANNGILWGNQCFITVVDNTRNINFGLSIYKqqaNMTNEYKYKSGDFRNYLRHVEEYEVEIIVELCKVPLDPDVLAH 400
Cdd:PHA02778  316 RAQGHNNGICWNNQLFVTVVDNTRNTNFTISVKT---DETPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAH 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 401 INVMNPRILDEWELAFVPPPPQGIEDSYRYILSLATKCPADVIPAEKPDPWDKYTFWEIDMTEKLSAELSQFSLGKRFLY 480
Cdd:PHA02778  393 LHTMNPSILEDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLF 472

                         490       500       510
                  ....*....|....*....|....*....|
gi 1149685236 481 QSGLL-KNKRIRDSDDIGETRRSVKRKRRN 509
Cdd:PHA02778  473 QAGLRrRTRRRKRKSTSSSSSRSTKRRRRK 502
Late_protein_L1 pfam00500
L1 (late) protein;
4-507 0e+00

L1 (late) protein;


Pssm-ID: 459833  Cd Length: 497  Bit Score: 754.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236   4 WMQTTGKLYLPPQkPVAKVLNTDDFIKRTGYYFHGGTERLLMVGHPYYDVMDtvDDEKVAVPKVSAQQFRVLRLRLPDPN 83
Cdd:pfam00500   1 WLPSQQKLYLPPQ-PVTKVLSTDEYVTRTNIFYHAGTDRLLTVGHPYFEIKG--RNDKVLVPKVSGNQYRVFRLKLPDPN 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236  84 KFAIADEKIFNPEKERLVWRLTGLEIGRGGPLGISPTGHPLFNKYTDTENPNTYPTKQdeNNDYRQDISVDPKQIQMFIV 163
Cdd:pfam00500  78 RFALPDKSLYDPDKERLVWALRGLEIGRGQPLGIGVTGHPLFNKFDDAENPNKYINAQ--GGDNRQNMAFDPKQTQMFIV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 164 GCTPATGEYWDVTKPCKDRPLNNGDCPPIELFHTYIQDGDMCEFGFGNANFESFQQDRAGVPLELTNETALWPDFLKMTK 243
Cdd:pfam00500 156 GCTPAIGEHWDKASPCPNQVPKTGDCPPIELKNTVIEDGDMCDIGFGAMDFKALQANKSDVPLDIVNSICKYPDYLKMAE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 244 DIYGDQVFFYSKREQLYARHYFAKAGVDGDALPPTSYLNPdDGKPQKDLGPYSYYSTPSGSLVSSDSNMFNRPYWLHRAL 323
Cdd:pfam00500 236 DPYGDSMFFYARREQMYARHFFSRAGTVGEAVPEDLYIKG-AGEEQNTLATSNYFGTPSGSLVSSDGQLFNRPYWLQRAQ 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 324 GANNGILWGNQCFITVVDNTRNINFGLSIYKQQANMTNeykYKSGDFRNYLRHVEEYEVEIIVELCKVPLDPDVLAHINV 403
Cdd:pfam00500 315 GHNNGICWNNQLFVTVVDNTRGTNFTISVKADENDETT---YDASNFKEYLRHVEEYELSFIFQLCKVKLTPENLAYLHT 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 404 MNPRILDEWELAFVPPPPQGIEDSYRYILSLATKCPADVIPAEKPDPWDKYTFWEIDMTEKLSAELSQFSLGKRFLYQSG 483
Cdd:pfam00500 392 MNPSILEDWNLGVTPPPSSSLEDTYRYIESLATKCPDNPPPAEKEDPYKGLKFWEVDLSERLSADLDQFPLGRKFLYQSG 471

                         490       500
                  ....*....|....*....|....*...
gi 1149685236 484 L----LKNKRIRDSDDigETRRSVKRKR 507
Cdd:pfam00500 472 LtqssSSTKRKAPASV--AVSRSSKRKR 497
 
Name Accession Description Interval E-value
PHA02778 PHA02778
major capsid L1 protein; Provisional
 1-509 0e+00

major capsid L1 protein; Provisional


Pssm-ID: 222928  Cd Length: 503  Bit Score: 867.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236   1 MSLWMQTTGKLYLPPQkPVAKVLNTDDFIKRTGYYFHGGTERLLMVGHPYYDVMDTvDDEKVAVPKVSAQQFRVLRLRLP 80
Cdd:PHA02778    1 MALWLPSSGKLYLPPT-PVAKVLSTDEYVTRTNIFYHASSDRLLTVGHPYFPIKDA-DKNKVTVPKVSGNQYRVFRVKLP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236  81 DPNKFAIADEKIFNPEKERLVWRLTGLEIGRGGPLGISPTGHPLFNKYTDTENPNTYPTKQDEnnDYRQDISVDPKQIQM 160
Cdd:PHA02778   79 DPNKFALPDKSVYNPEKERLVWALRGLEVGRGQPLGVGVTGHPLFNKLKDTENPNKYPTAQGT--DDRQNVSFDPKQTQL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 161 FIVGCTPATGEYWDVTKPCKDRPLNNGDCPPIELFHTYIQDGDMCEFGFGNANFESFQQDRAGVPLELTNETALWPDFLK 240
Cdd:PHA02778  157 FIVGCTPALGEHWDKAKPCADAPPQAGDCPPIELKNSVIEDGDMVDIGFGAMNFKALQANKSDVPLDIVNSICKYPDYLK 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 241 MTKDIYGDQVFFYSKREQLYARHYFAKAGVDGDALPPTSYLNPDDGKPQKdLGPYSYYSTPSGSLVSSDSNMFNRPYWLH 320
Cdd:PHA02778  237 MANDPYGDSMFFFARREQMYARHFFTRAGTVGEAIPEDLYLKGASGQAQT-LGSSVYFPTPSGSLVSSDAQLFNRPYWLQ 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 321 RALGANNGILWGNQCFITVVDNTRNINFGLSIYKqqaNMTNEYKYKSGDFRNYLRHVEEYEVEIIVELCKVPLDPDVLAH 400
Cdd:PHA02778  316 RAQGHNNGICWNNQLFVTVVDNTRNTNFTISVKT---DETPQTTYKASNFKEYLRHVEEYELSFIFQLCKVPLTPEVLAH 392

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 401 INVMNPRILDEWELAFVPPPPQGIEDSYRYILSLATKCPADVIPAEKPDPWDKYTFWEIDMTEKLSAELSQFSLGKRFLY 480
Cdd:PHA02778  393 LHTMNPSILEDWNLGFVPPPSSSLEDTYRYIQSLATKCPDNVPPKEKEDPYAKYTFWEVDLTERFSLDLDQFPLGRKFLF 472

                         490       500       510
                  ....*....|....*....|....*....|
gi 1149685236 481 QSGLL-KNKRIRDSDDIGETRRSVKRKRRN 509
Cdd:PHA02778  473 QAGLRrRTRRRKRKSTSSSSSRSTKRRRRK 502
Late_protein_L1 pfam00500
L1 (late) protein;
4-507 0e+00

L1 (late) protein;


Pssm-ID: 459833  Cd Length: 497  Bit Score: 754.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236   4 WMQTTGKLYLPPQkPVAKVLNTDDFIKRTGYYFHGGTERLLMVGHPYYDVMDtvDDEKVAVPKVSAQQFRVLRLRLPDPN 83
Cdd:pfam00500   1 WLPSQQKLYLPPQ-PVTKVLSTDEYVTRTNIFYHAGTDRLLTVGHPYFEIKG--RNDKVLVPKVSGNQYRVFRLKLPDPN 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236  84 KFAIADEKIFNPEKERLVWRLTGLEIGRGGPLGISPTGHPLFNKYTDTENPNTYPTKQdeNNDYRQDISVDPKQIQMFIV 163
Cdd:pfam00500  78 RFALPDKSLYDPDKERLVWALRGLEIGRGQPLGIGVTGHPLFNKFDDAENPNKYINAQ--GGDNRQNMAFDPKQTQMFIV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 164 GCTPATGEYWDVTKPCKDRPLNNGDCPPIELFHTYIQDGDMCEFGFGNANFESFQQDRAGVPLELTNETALWPDFLKMTK 243
Cdd:pfam00500 156 GCTPAIGEHWDKASPCPNQVPKTGDCPPIELKNTVIEDGDMCDIGFGAMDFKALQANKSDVPLDIVNSICKYPDYLKMAE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 244 DIYGDQVFFYSKREQLYARHYFAKAGVDGDALPPTSYLNPdDGKPQKDLGPYSYYSTPSGSLVSSDSNMFNRPYWLHRAL 323
Cdd:pfam00500 236 DPYGDSMFFYARREQMYARHFFSRAGTVGEAVPEDLYIKG-AGEEQNTLATSNYFGTPSGSLVSSDGQLFNRPYWLQRAQ 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 324 GANNGILWGNQCFITVVDNTRNINFGLSIYKQQANMTNeykYKSGDFRNYLRHVEEYEVEIIVELCKVPLDPDVLAHINV 403
Cdd:pfam00500 315 GHNNGICWNNQLFVTVVDNTRGTNFTISVKADENDETT---YDASNFKEYLRHVEEYELSFIFQLCKVKLTPENLAYLHT 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149685236 404 MNPRILDEWELAFVPPPPQGIEDSYRYILSLATKCPADVIPAEKPDPWDKYTFWEIDMTEKLSAELSQFSLGKRFLYQSG 483
Cdd:pfam00500 392 MNPSILEDWNLGVTPPPSSSLEDTYRYIESLATKCPDNPPPAEKEDPYKGLKFWEVDLSERLSADLDQFPLGRKFLYQSG 471

                         490       500
                  ....*....|....*....|....*...
gi 1149685236 484 L----LKNKRIRDSDDigETRRSVKRKR 507
Cdd:pfam00500 472 LtqssSSTKRKAPASV--AVSRSSKRKR 497
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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