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Conserved domains on  [gi|1149166385|ref|WP_077726998|]
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transposase [Lactiplantibacillus plantarum]

Protein Classification

transposase family protein( domain architecture ID 1750152)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0015074|GO:0032196|GO:0003677
PubMed:  20067338

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS982 super family cl41299
IS982 family transposase; Currently, there are 46 seed sequences in this family.
 2-129 3.98e-37

IS982 family transposase; Currently, there are 46 seed sequences in this family.


The actual alignment was detected with superfamily member NF033520:

Pssm-ID: 468056 [Multi-domain]  Cd Length: 243  Bit Score: 126.19  E-value: 3.98e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149166385   2 RNHRAKVFRETANIDYNATKKLYYYSFKGNLEVANNGIVLTYDVTPASWHAIKSVQTLLSLWPSHQILV-DLGYLSRKLK 80
Cdd:NF033520   88 RIKRHKVFKGIADRGYCASKKGWFYGFKLHLLVNLSGEIVSYVITPANVHDRKVLEDLLLTKPLPGKLFgDKGYISKELQ 167

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1149166385  81 QELAKKKINLWTPVRRNMKQ--PVAYQRLLNRQRRQSETNFSQLNELFDIE 129
Cdd:NF033520  168 EKLKEQGITLITPLRKNMKEklEKPNDKLLLRKRKRIETVFSQLKNQFGIE 218
 
Name Accession Description Interval E-value
transpos_IS982 NF033520
IS982 family transposase; Currently, there are 46 seed sequences in this family.
 2-129 3.98e-37

IS982 family transposase; Currently, there are 46 seed sequences in this family.


Pssm-ID: 468056 [Multi-domain]  Cd Length: 243  Bit Score: 126.19  E-value: 3.98e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149166385   2 RNHRAKVFRETANIDYNATKKLYYYSFKGNLEVANNGIVLTYDVTPASWHAIKSVQTLLSLWPSHQILV-DLGYLSRKLK 80
Cdd:NF033520   88 RIKRHKVFKGIADRGYCASKKGWFYGFKLHLLVNLSGEIVSYVITPANVHDRKVLEDLLLTKPLPGKLFgDKGYISKELQ 167

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1149166385  81 QELAKKKINLWTPVRRNMKQ--PVAYQRLLNRQRRQSETNFSQLNELFDIE 129
Cdd:NF033520  168 EKLKEQGITLITPLRKNMKEklEKPNDKLLLRKRKRIETVFSQLKNQFGIE 218
DDE_Tnp_1_3 pfam13612
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 2-129 4.58e-14

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433348  Cd Length: 154  Bit Score: 64.26  E-value: 4.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149166385   2 RNHRAKVFRETANIDYNATKklYYYSFKGNLEVANNGIVLTYDVTPASWHAIKSVQTLL-SLwpSHQILVDLGYLSRKLK 80
Cdd:pfam13612  21 RIPRHKVFKGLAKRGKSSMG--WFYGFKLHLIINDRGEILAFKLTPGNVDDRKPVETLSkGL--FGKLFGDKGYISQKLF 96

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1149166385  81 QELAKKKINLWTPVRRNMKQPV--AYQRLLNRQRRQSETNFSQLNELFDIE 129
Cdd:pfam13612  97 DQLLEDGIELITNLRKNMKNKLmsLWDKALLRKRSLIETVNDQLKNISQIE 147
transpos_IS4_1 NF033592
IS4 family transposase;
35-99 2.29e-03

IS4 family transposase;


Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 36.47  E-value: 2.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1149166385  35 ANNGIVLTYDVTPASWHAIKSVQTLLSLWPSHQILV-DLGYLSRKLKQELAKKKINLWTPVRRNMK 99
Cdd:NF033592  146 LLSGLPLDAAITPGKTHERTLLRQLLETLPPGDLLLfDRGYFSYELFAEIQEAGAYFVSRLKSNTN 211
 
Name Accession Description Interval E-value
transpos_IS982 NF033520
IS982 family transposase; Currently, there are 46 seed sequences in this family.
 2-129 3.98e-37

IS982 family transposase; Currently, there are 46 seed sequences in this family.


Pssm-ID: 468056 [Multi-domain]  Cd Length: 243  Bit Score: 126.19  E-value: 3.98e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149166385   2 RNHRAKVFRETANIDYNATKKLYYYSFKGNLEVANNGIVLTYDVTPASWHAIKSVQTLLSLWPSHQILV-DLGYLSRKLK 80
Cdd:NF033520   88 RIKRHKVFKGIADRGYCASKKGWFYGFKLHLLVNLSGEIVSYVITPANVHDRKVLEDLLLTKPLPGKLFgDKGYISKELQ 167

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1149166385  81 QELAKKKINLWTPVRRNMKQ--PVAYQRLLNRQRRQSETNFSQLNELFDIE 129
Cdd:NF033520  168 EKLKEQGITLITPLRKNMKEklEKPNDKLLLRKRKRIETVFSQLKNQFGIE 218
DDE_Tnp_1_3 pfam13612
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 2-129 4.58e-14

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433348  Cd Length: 154  Bit Score: 64.26  E-value: 4.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149166385   2 RNHRAKVFRETANIDYNATKklYYYSFKGNLEVANNGIVLTYDVTPASWHAIKSVQTLL-SLwpSHQILVDLGYLSRKLK 80
Cdd:pfam13612  21 RIPRHKVFKGLAKRGKSSMG--WFYGFKLHLIINDRGEILAFKLTPGNVDDRKPVETLSkGL--FGKLFGDKGYISQKLF 96

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1149166385  81 QELAKKKINLWTPVRRNMKQPV--AYQRLLNRQRRQSETNFSQLNELFDIE 129
Cdd:pfam13612  97 DQLLEDGIELITNLRKNMKNKLmsLWDKALLRKRSLIETVNDQLKNISQIE 147
DDE_Tnp_1 pfam01609
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 7-112 7.98e-06

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.


Pssm-ID: 376573 [Multi-domain]  Cd Length: 196  Bit Score: 43.00  E-value: 7.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149166385   7 KVFRETANIDYNATKKLYYYSFKGNLEV-ANNGIVLTYDVTPASWHAIKSVQTLLSLWPSHQ---ILVDLGYLSRKLKQE 82
Cdd:pfam01609  15 RTPGTGEDARWGYDGGKRRYGYKLHIAVdTRTGLILAVVLTPGNVHDSKGLLQLLDELRRRKgrlVLADAGYGGKELLDK 94

                          90       100       110
                  ....*....|....*....|....*....|
gi 1149166385  83 LAKKKINLWTPVRRNMKQPVAYQRLLNRQR 112
Cdd:pfam01609  95 LEEKGVDYLIRLKKNAKLIDDKRRGRLRKH 124
transpos_IS4_1 NF033592
IS4 family transposase;
35-99 2.29e-03

IS4 family transposase;


Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 36.47  E-value: 2.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1149166385  35 ANNGIVLTYDVTPASWHAIKSVQTLLSLWPSHQILV-DLGYLSRKLKQELAKKKINLWTPVRRNMK 99
Cdd:NF033592  146 LLSGLPLDAAITPGKTHERTLLRQLLETLPPGDLLLfDRGYFSYELFAEIQEAGAYFVSRLKSNTN 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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