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Conserved domains on  [gi|1139715576|gb|APZ84591|]
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RAD51 recombinase, partial [Zea mays subsp. mays]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03186 super family cl31979
DNA repair protein RAD51 homolog; Provisional
 6-141 4.05e-85

DNA repair protein RAD51 homolog; Provisional


The actual alignment was detected with superfamily member PLN03186:

Pssm-ID: 178728 [Multi-domain]  Cd Length: 342  Bit Score: 252.35  E-value: 4.05e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576   6 AHQKASPPIEEEATEHGPFPIEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPL 85
Cdd:PLN03186    8 AAAQAMQEEEEEEAAHGPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKLVPL 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1139715576  86 GFTSASQLHAQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:PLN03186   88 GFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTL 143
 
Name Accession Description Interval E-value
PLN03186 PLN03186
DNA repair protein RAD51 homolog; Provisional
 6-141 4.05e-85

DNA repair protein RAD51 homolog; Provisional


Pssm-ID: 178728 [Multi-domain]  Cd Length: 342  Bit Score: 252.35  E-value: 4.05e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576   6 AHQKASPPIEEEATEHGPFPIEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPL 85
Cdd:PLN03186    8 AAAQAMQEEEEEEAAHGPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKLVPL 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1139715576  86 GFTSASQLHAQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:PLN03186   88 GFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTL 143
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
 26-141 3.10e-69

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 211.12  E-value: 3.10e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576  26 IEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPLGFTSASQLHAQRLEIIQLTT 105
Cdd:TIGR02239   1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1139715576 106 GSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:TIGR02239  81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTL 116
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
 85-141 3.31e-33

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 117.02  E-value: 3.31e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1139715576  85 LGFTSASQLHAQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:pfam08423   1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTL 57
Rad51 cd19513
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ...
 103-141 4.62e-24

RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.


Pssm-ID: 410921 [Multi-domain]  Cd Length: 235  Bit Score: 92.77  E-value: 4.62e-24
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19513     1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTL 39
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
95-139 4.85e-08

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 50.17  E-value: 4.85e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1139715576  95 AQRLEIIQLTTGSRELDQIL-DGGIETGSITEMYGEFRSGKTQLCH 139
Cdd:COG0468    36 KARQDVEVISTGSLALDIALgVGGLPRGRIVEIYGPESSGKTTLAL 81
 
Name Accession Description Interval E-value
PLN03186 PLN03186
DNA repair protein RAD51 homolog; Provisional
 6-141 4.05e-85

DNA repair protein RAD51 homolog; Provisional


Pssm-ID: 178728 [Multi-domain]  Cd Length: 342  Bit Score: 252.35  E-value: 4.05e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576   6 AHQKASPPIEEEATEHGPFPIEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPL 85
Cdd:PLN03186    8 AAAQAMQEEEEEEAAHGPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKLVPL 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1139715576  86 GFTSASQLHAQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:PLN03186   88 GFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTL 143
PTZ00035 PTZ00035
Rad51 protein; Provisional
 8-141 4.23e-71

Rad51 protein; Provisional


Pssm-ID: 185407 [Multi-domain]  Cd Length: 337  Bit Score: 216.40  E-value: 4.23e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576   8 QKASPPIEEEATEHGPFPIEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPLGF 87
Cdd:PTZ00035    5 QNEQQEEEEEEEAEGFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVPMGF 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1139715576  88 TSASQLHAQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:PTZ00035   85 ISATEYLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTL 138
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
 26-141 3.10e-69

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 211.12  E-value: 3.10e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576  26 IEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPLGFTSASQLHAQRLEIIQLTT 105
Cdd:TIGR02239   1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1139715576 106 GSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:TIGR02239  81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTL 116
PLN03187 PLN03187
meiotic recombination protein DMC1 homolog; Provisional
 15-141 2.32e-49

meiotic recombination protein DMC1 homolog; Provisional


Pssm-ID: 215620 [Multi-domain]  Cd Length: 344  Bit Score: 161.10  E-value: 2.32e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576  15 EEEATEhgpfPIEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPLGFTSASQLH 94
Cdd:PLN03187   24 EEDLFE----SIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQGFITGSDAL 99

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1139715576  95 AQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:PLN03187  100 LKRKSVVRITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTL 146
recomb_DMC1 TIGR02238
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ...
 26-141 2.65e-47

meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.


Pssm-ID: 131292 [Multi-domain]  Cd Length: 313  Bit Score: 154.94  E-value: 2.65e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576  26 IEQLQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPLGFTSASQLHAQRLEIIQLTT 105
Cdd:TIGR02238   1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1139715576 106 GSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:TIGR02238  81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTL 116
radA PRK04301
DNA repair and recombination protein RadA; Validated
 39-141 2.22e-37

DNA repair and recombination protein RadA; Validated


Pssm-ID: 235273 [Multi-domain]  Cd Length: 317  Bit Score: 129.23  E-value: 2.22e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576  39 VKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPL-GFTSASQLHAQRLEIIQLTTGSRELDQILDGG 117
Cdd:PRK04301   19 AEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADIgGFETALEVLERRKNVGKITTGSKELDELLGGG 98

                          90       100
                  ....*....|....*....|....
gi 1139715576 118 IETGSITEMYGEFRSGKTQLCHTL 141
Cdd:PRK04301   99 IETQSITEFYGEFGSGKTQICHQL 122
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
 85-141 3.31e-33

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 117.02  E-value: 3.31e-33
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1139715576  85 LGFTSASQLHAQRLEIIQLTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:pfam08423   1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTL 57
recomb_radA TIGR02236
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ...
 33-141 1.16e-32

DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 131290 [Multi-domain]  Cd Length: 310  Bit Score: 116.77  E-value: 1.16e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1139715576  33 GIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASKLVPLG-FTSASQLHAQRLEIIQLTTGSRELD 111
Cdd:TIGR02236   6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELD 85

                          90       100       110
                  ....*....|....*....|....*....|
gi 1139715576 112 QILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:TIGR02236  86 ELLGGGIETQAITEVFGEFGSGKTQICHQL 115
Rad51 cd19513
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ...
 103-141 4.62e-24

RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.


Pssm-ID: 410921 [Multi-domain]  Cd Length: 235  Bit Score: 92.77  E-value: 4.62e-24
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19513     1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTL 39
DMC1 cd19514
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ...
 103-141 3.89e-19

homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.


Pssm-ID: 410922 [Multi-domain]  Cd Length: 236  Bit Score: 79.71  E-value: 3.89e-19
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19514     1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTL 39
Rad51_DMC1_archRadA cd01123
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ...
 103-141 8.49e-19

recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .


Pssm-ID: 410868 [Multi-domain]  Cd Length: 234  Bit Score: 79.11  E-value: 8.49e-19
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd01123     1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTL 39
archRadA cd19515
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ...
 103-141 9.60e-17

archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)


Pssm-ID: 410923 [Multi-domain]  Cd Length: 233  Bit Score: 73.55  E-value: 9.60e-17
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19515     1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQL 39
radB PRK09361
DNA repair and recombination protein RadB; Provisional
 103-138 3.62e-10

DNA repair and recombination protein RadB; Provisional


Pssm-ID: 236482 [Multi-domain]  Cd Length: 225  Bit Score: 55.64  E-value: 3.62e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLC 138
Cdd:PRK09361    5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNIC 40
archRadB cd01394
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ...
 103-141 1.19e-08

archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.


Pssm-ID: 410882 [Multi-domain]  Cd Length: 216  Bit Score: 51.55  E-value: 1.19e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd01394     1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQL 39
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
95-139 4.85e-08

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 50.17  E-value: 4.85e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1139715576  95 AQRLEIIQLTTGSRELDQIL-DGGIETGSITEMYGEFRSGKTQLCH 139
Cdd:COG0468    36 KARQDVEVISTGSLALDIALgVGGLPRGRIVEIYGPESSGKTTLAL 81
XRCC3 cd19491
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ...
 110-141 1.04e-07

XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410899 [Multi-domain]  Cd Length: 250  Bit Score: 49.21  E-value: 1.04e-07
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1139715576 110 LDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19491     1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQL 32
recomb_radB TIGR02237
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ...
 110-141 7.69e-07

DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).


Pssm-ID: 274047 [Multi-domain]  Cd Length: 209  Bit Score: 46.26  E-value: 7.69e-07
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1139715576 110 LDQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:TIGR02237   1 IDELLGGGVERGTITQIYGPPGSGKTNICMIL 32
HHH_5 pfam14520
Helix-hairpin-helix domain;
29-81 1.45e-06

Helix-hairpin-helix domain;


Pssm-ID: 434010 [Multi-domain]  Cd Length: 57  Bit Score: 42.86  E-value: 1.45e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1139715576  29 LQASGIAALDVKKLKDAGLCTVESVAYSPRKDLLQIKGISEAKVDKIIEAASK 81
Cdd:pfam14520   5 LSISGIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
Rad51B cd19493
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ...
 111-141 8.57e-06

RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410901 [Multi-domain]  Cd Length: 222  Bit Score: 43.46  E-value: 8.57e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1139715576 111 DQILDGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19493     1 DTALAGGLPLGAITEITGASGSGKTQFALTL 31
Rad51D cd19489
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ...
 115-141 1.77e-05

RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410897 [Multi-domain]  Cd Length: 209  Bit Score: 42.62  E-value: 1.77e-05
                          10        20
                  ....*....|....*....|....*..
gi 1139715576 115 DGGIETGSITEMYGEFRSGKTQLCHTL 141
Cdd:cd19489     1 GGGLRTGEITELVGESSSGKTQLCLTA 27
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
103-140 2.62e-04

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 39.13  E-value: 2.62e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1139715576 103 LTTGSRELDQILDGGIETGSITEMYGEFRSGKTQLCHT 140
Cdd:COG0467     2 VPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQ 39
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 121-141 7.30e-04

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 37.72  E-value: 7.30e-04
                          10        20
                  ....*....|....*....|.
gi 1139715576 121 GSITEMYGEFRSGKTQLCHTL 141
Cdd:cd01393     1 GKITEIYGPPGSGKTQLALQL 21
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 74-137 5.53e-03

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 35.45  E-value: 5.53e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1139715576  74 KIIEAASKLVPLGFTSASQL---HAQRLEIIQLTTGSRELDQILD-GGIETGSITEMYGEFRSGKTQL 137
Cdd:pfam00154   1 KALEAALKQIEKQFGKGSIMklgDEKKLDVETISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTL 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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