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Conserved domains on  [gi|1127921417|gb|APT35244|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Lichmera lombokia]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-279 2.49e-120

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 347.97  E-value: 2.49e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTA 279
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-279 2.49e-120

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 347.97  E-value: 2.49e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTA 279
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 8.93e-13

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 66.95  E-value: 8.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  23 SNHWIMAWAGLEINTLAVLPLI-SKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWHTGQWDIAQLTHPTSCLILT** 101
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 102 *******************-----------------**************KLPPMTLLYLVSHSLNPSLLTTMAILSTSL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVpfhtwlpdayegaptpvSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 165 GGWMGLNQTQIRKILAFSSISHLGWMAVII----CYDPKLTLLNFYLYSLITASVFL-----TLNVTKTLKLSTLLTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1127921417 236 KAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 139-281 3.34e-11

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 63.21  E-value: 3.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 139 MTLLYLVSHSLNPS---LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAV-IICYDPK-LTLLNFYL--YSLI 211
Cdd:COG1007   254 LRLLVEAFPGLAADwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLlaYLFM 333

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1127921417 212 TASVFLTLN-VTKTLKLSTLLTSW----TKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:COG1007   334 NLGAFAVILlLSRKGGEAEEIEDLaglaRRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVI 408
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-279 2.49e-120

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 347.97  E-value: 2.49e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTA 279
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-279 4.69e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 294.02  E-value: 4.69e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSlNPSLLTTMAIL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTA 278
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-279 1.06e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 290.28  E-value: 1.06e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLA 279
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-279 1.40e-84

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 257.08  E-value: 1.40e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILP 279
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-281 2.02e-71

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 223.31  E-value: 2.02e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATI 281
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-267 1.43e-57

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 187.83  E-value: 1.43e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGQWDIAQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAIL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                         250       260
                  ....*....|....*....|....*..
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISL 267
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-275 1.94e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 142.65  E-value: 1.94e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   1 MNPQAKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWH 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  81 TGqwdiaqLTHPTSCLILT***********************************KLPPMTLLylvSHSLNPSLLTTMAIL 160
Cdd:MTH00160   82 LM------LFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILL---SYLINNNFIIIIIIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 161 STSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFL 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSM 275
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNM 267
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 5-275 9.30e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 127.69  E-value: 9.30e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   5 AKLIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWHTGQW 84
Cdd:MTH00144    5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  85 DI-------------------------AQLTHPTSCLILT***********************************KLPPM 139
Cdd:MTH00144   85 FSmsllllglclklglfpfhfwvpsvmAGLSWLSCFLLLTWQ---------------------------------KVAPL 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 140 TLL-YLVSHSLNPSLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLT 218
Cdd:MTH00144  132 FLLsNFLDLYWLAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFS 211

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1127921417 219 LNVTKTLKLSTLLTSWTKAPFLITALCLtLLSLAGLPPLTGFLPKWLIIQELTKQSM 275
Cdd:MTH00144  212 LWSGDSGSMKDLGSLKPSYKTGLSIISL-LLSLGGLPPFLGFCSKLLVLISSMESSP 267
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 7-275 1.07e-33

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 124.89  E-value: 1.07e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   7 LIFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSmtnawhTGQWDI 86
Cdd:MTH00011    9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  87 AQLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTTMAILSTSLGG 166
Cdd:MTH00011   83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 167 WMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFLITALCL 246
Cdd:MTH00011  163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFI 242

                         250       260
                  ....*....|....*....|....*....
gi 1127921417 247 TLLSLAGLPPLTGFLPKWLIIQELTKQSM 275
Cdd:MTH00011  243 MLLSLGGLPPFTGFMPKLMAIETLTSNSM 271
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-270 2.45e-27

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 107.84  E-value: 2.45e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417   8 IFTFSLLLGTTITISSNHWIMAWAGLEINTLAVLPLISKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWHTgqwdia 87
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  88 qLTHPTSCLILT***********************************KLPPMTLLYLVSHslNPSLLTTMAILSTSLGGW 167
Cdd:MTH00197   76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGGI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 168 MGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLITASVFLTLNVTKTLKLSTLLTSWTKAPFLITALCLT 247
Cdd:MTH00197  153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                         250       260
                  ....*....|....*....|...
gi 1127921417 248 LLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:MTH00197  233 FLSLGGLPPLSGFFLKWLILTSL 255
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-267 8.42e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 70.44  E-value: 8.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  13 LLLGTTITISSNHWIMAWAGLEINTLAVLPLI-SKSHHPRAVEAATKYF*VQAAASTLILFS-------------SMTNA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  79 WHTGQWDIAQLTHPTSCLILT***********************************KLPPMTLLylVSHSLNPSLLTTMA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSIL--VSIGLNVNILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 159 ILSTSLGGWMGLNQTQIRKILAFSSISHLGW------MAVIICYDPKLTLLNFYLY-SLITASVFLTLNVTKTL--KLST 229
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFvlwgieIGSFESIQASLVYLFIYIImSICVFSIILALNVYKNLiiEFSG 239

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1127921417 230 LLTswtKAPFLITALCLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00196  240 LSR---RLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 8.93e-13

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 66.95  E-value: 8.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  23 SNHWIMAWAGLEINTLAVLPLI-SKSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWHTGQWDIAQLTHPTSCLILT** 101
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 102 *******************-----------------**************KLPPMTLLYLVSHSLNPSLLTTMAILSTSL 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVpfhtwlpdayegaptpvSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 165 GGWMGLNQTQIRKILAFSSISHLGWMAVII----CYDPKLTLLNFYLYSLITASVFL-----TLNVTKTLKLSTLLTSWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1127921417 236 KAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 139-281 3.34e-11

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 63.21  E-value: 3.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 139 MTLLYLVSHSLNPS---LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAV-IICYDPK-LTLLNFYL--YSLI 211
Cdd:COG1007   254 LRLLVEAFPGLAADwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLgLAAGTPLgVSAALFYLlaYLFM 333

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1127921417 212 TASVFLTLN-VTKTLKLSTLLTSW----TKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:COG1007   334 NLGAFAVILlLSRKGGEAEEIEDLaglaRRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVI 408
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-267 9.10e-10

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 58.87  E-value: 9.10e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  13 LLLGTTITISSNHWIMAWAGLEINTLAVLPLIS-KSHHPRAVEAATKYF*VQAAASTLILFSSMTNAWHTGQWDI----A 87
Cdd:MTH00199  106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417  88 QLTHPTSCLILT***********************************KLPPMTLLYLVSHSLNPSLLTtmAILSTSLGGW 167
Cdd:MTH00199  186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAI 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 168 MGLNQTQIRKILAFSSISHLGW----MAVIICYDPKLTLLNFYLYSLITASVF---LTLNVTKTLKLSTLLTSwTKAPFL 240
Cdd:MTH00199  264 GALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSICSFsiiLSLKLTKGLIVEVSGLS-RKNPVI 342

                         250       260
                  ....*....|....*....|....*..
gi 1127921417 241 ITALCLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199  343 ALTLALTFLSIAGIPPLAGFLSKWLIL 369
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
153-281 2.63e-09

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 57.52  E-value: 2.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWM--AVIICYDPKLTLLNFYL--YSLITASVFLTLN-VTKTLKL 227
Cdd:PRK05777  272 VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvGLAAGTAEGYSAVLFYLlaYLFMTLGAFGVISlLRRKGGE 351

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1127921417 228 STLLTSWT----KAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:PRK05777  352 AESISDFAglskRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVI 409
ndhB CHL00049
NADH dehydrogenase subunit 2
 152-263 5.89e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 56.55  E-value: 5.89e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 152 SLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAV-IICYDPK------LTLLNFYLYSLITASVFLTL--NVT 222
Cdd:CHL00049  281 LLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVGDSNdgyasmITYMLFYIFMNLGTFACIVLfgLRT 360

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1127921417 223 KTLKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPK 263
Cdd:CHL00049  361 GTDNIRDYAGLYTKDPFLALSLALCLLSLGGIPPLAGFFGK 401
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 153-281 9.44e-09

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 55.54  E-value: 9.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLY----SLITASVFLT----LNVTKT 224
Cdd:COG0651   274 LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLAagaiERATGT 353

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1127921417 225 LKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:COG0651   354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAV 410
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 144-267 7.15e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 53.32  E-value: 7.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 144 LVSHSLNPSLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYSLI-TASVFLTLNVT 222
Cdd:MTH00198  349 LTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTyLVSALASFTVI 428

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1127921417 223 KTL------------------------KLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00198  429 CTLeefgtrtptsrqrdgsfgnynlvrRLVDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIL 497
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 160-279 1.56e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 52.31  E-value: 1.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 160 LSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTL-------LNFYLYS----LITASVFLTlnvTKTLKLS 228
Cdd:PRK08668  281 ISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFagglfhvFNHALFKglffLIFAAVIYR---TGTTKIS 357

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1127921417 229 TLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTA 279
Cdd:PRK08668  358 EMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITA 408
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
153-263 1.56e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.98  E-value: 1.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGW-MAVIIC-----YDPKLTLLNFYLYSLITA--SVFLTLNVTKT 224
Cdd:PRK02504  278 LFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvMIGLVAgteagYASMVFYLLAYLFMNLGAfaCVILFSLRTGT 357

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1127921417 225 LKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPK 263
Cdd:PRK02504  358 DQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 154-267 2.96e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 51.27  E-value: 2.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 154 LTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLY----SLITASVFLTLNVTK----TL 225
Cdd:PRK12662  282 FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYivnhSIVKSALFMVSGSISyhfgTT 361

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1127921417 226 KLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLII 267
Cdd:PRK12662  362 KLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYIL 403
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 164-263 7.10e-07

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 50.31  E-value: 7.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 164 LGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPK------LTLLnfYLYSLITASVFLTLNV------TKTL-KLSTL 230
Cdd:PRK12644  280 LGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRdaalagLAML--LAHALFKAALFLVVGIidhstgTRDIrKLSGL 357

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1127921417 231 ltsWTKAPFLITALCLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12644  358 ---GRRQPVLAVVAALAAASMAGLPPLLGFVAK 387
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 148-270 1.12e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 49.38  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 148 SLNPSLLTTMAILSTS---LGGWMGLNQTQIRKILAFSSISHLGWMAVIICydpkltllnfylYSLITASVFLTLN--VT 222
Cdd:COG1009   269 ALSPVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYMFLALG------------VGAYVAALFHLLThaFF 336

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1127921417 223 KTL------------------KLSTLltsWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQEL 270
Cdd:COG1009   337 KALlflgagsvihatgtrdirKMGGL---RKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAA 399
PRK12650 PRK12650
DUF4040 family protein;
153-263 4.19e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 47.73  E-value: 4.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTL----LNFYLYSLITASVFLTLNV----TKT 224
Cdd:PRK12650  274 LLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALtaavVHTLAHALFKSSLFMLIGVvdhqAGT 353

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1127921417 225 LKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12650  354 RDIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGFVSK 392
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 152-281 6.42e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.18  E-value: 6.42e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 152 SLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLN--FYL--YSLITASVFLTLN----VTK 223
Cdd:PRK08375  272 WLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAGaievTYG 351

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1127921417 224 TLKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:PRK08375  352 TRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAV 409
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
139-268 3.59e-05

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 44.94  E-value: 3.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 139 MTLLYLVSHSLNPSLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAViicydpKLTLLN--------FYLYSL 210
Cdd:PRK12663  260 FTLLFPQERELLHPLLATMAAITMVIGALGALAYKDIRRIAGYQVISSIGFILL------GLALGTpagingaiFYLVHD 333

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1127921417 211 ITASVFLTL------NVTKTLKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK12663  334 MVVKTALFLiagslvRLTGYRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQ 397
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 139-281 8.70e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 43.53  E-value: 8.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 139 MTLLYLVSHSLNPsLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICydpkltLLN--------FYLYS- 209
Cdd:COG1008   264 LPLFPEASAYFAP-LLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIF------ALNplglqgavLQMVSh 336

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1127921417 210 -LITASVFLTLNV----TKTLKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQELTKQSMAPTAVA 281
Cdd:COG1008   337 gLITAALFLLVGVlydrTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNPWLAILA 413
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 153-266 1.35e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 42.98  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLY----SLITASVFLTLNV----TKT 224
Cdd:PRK12647  261 ILPLFGGLTMLTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFlvahSLYKGALFMVAGIidheTGT 340

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1127921417 225 LKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK12647  341 RDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELI 382
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 153-271 2.38e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 42.25  E-value: 2.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYL--YSLITASVFL---------TLNV 221
Cdd:MTH00032  291 IITIFGALTAFFAATVGLVQNDLKKVIAYSTCSQLGYMVLIIGIEGSHNVGLFHLvnHAFFKALLFLsagsvihstTVDE 370

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1127921417 222 TKTLKLSTLLTSwtkAPFLITALCLTLLSLAGLPPLTGFLPKWLIIqELT 271
Cdd:MTH00032  371 QDMRKMGGLIHS---IPFTYTMMLIGSFSIMGLPYLTGFYSKDLIL-ELT 416
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
153-268 5.74e-04

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 41.17  E-value: 5.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKLTLLNFYLYS----LITASVFL----TLNVTKT 224
Cdd:PRK06277  268 VLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAinhvIYKSALFLgagiVSYRTKT 347

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1127921417 225 LKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK06277  348 SNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAQ 391
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 157-266 6.81e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 40.85  E-value: 6.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 157 MAILSTSLGGWMGLNQTQIRKILAFSSISHLGWM------AVIICYDPKLT----------LLNFYLYSLITASVFLTLN 220
Cdd:PRK08376  293 LGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMllglgvGLAALGDPAMAsygeialaggIYHIVNHALYKALLFLTAG 372

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1127921417 221 V------TKTL-KLSTLLTS--WTKAPFLITALcltllSLAGLPPLTGFLPKWLI 266
Cdd:PRK08376  373 AviyetgTRNLnELGGLARTmpKTTIAFLIGAA-----AIVGLPPFNGFASKWLI 422
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 153-263 2.13e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 39.43  E-value: 2.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICY----DPKLTLL--NFYL--YSLITASVFLTLNVTK- 223
Cdd:PRK12649  280 LVSGTGMITMVLAGFLAFRQTDIKAILAYSTISQLAYLMTMYGYttyhEPGLGVAaaTFHLlnHATFKACLFLVAGIVAh 359

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1127921417 224 ---TLKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPK 263
Cdd:PRK12649  360 eaaTRDIRKLGGLRKEMPITFIVASIAALAMAGIPPLNGFLSK 402
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 146-267 7.65e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 37.49  E-value: 7.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 146 SHSLNPsLLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGW--MAVIICYDPKLTLLNFYLYS--LITASVFLTLNV 221
Cdd:PRK05846  273 SHEFAP-IIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFvtLGIFAGNQLGIQGAIFQMIShgLSSAALFLLVGV 351

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1127921417 222 ----TKTLKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLII 267
Cdd:PRK05846  352 lydrLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLIL 401
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 153-268 7.91e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 37.60  E-value: 7.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMAVIICYDPKL----TLLNFYLYSLITASVFLT----LNVTKT 224
Cdd:PRK06458  283 LLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLgifaALLHMLNHSLTKSAIFFAsgnvLQKYGT 362

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1127921417 225 LKLSTLLTSWTKAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK06458  363 RDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILT 406
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 153-268 8.98e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 37.36  E-value: 8.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127921417 153 LLTTMAILSTSLGGWMGLNQTQIRKILAFSSISHLGWMaVIIC----YDPKL-TLLN--FY--LYSLITASVFLTLNVTK 223
Cdd:MTH00020  276 IVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCSQLGYM-VVACglshYSISLfHLMNhaFFkaLLFLSAGSVIHALSDEQ 354

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1127921417 224 TL-KLSTLLTSwtkAPFLITALCLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:MTH00020  355 DMrKMGGLISF---LPLTYIFFLIGSLSLMGFPYLTGFYSKDLILE 397
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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