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Conserved domains on  [gi|1127884959|emb|CCP51232|]
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putative cell cycle regulator [Brucella phage Tb]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5352 super family cl44222
Uncharacterized conserved protein [Function unknown];
5-57 2.98e-12

Uncharacterized conserved protein [Function unknown];


The actual alignment was detected with superfamily member COG5352:

Pssm-ID: 444133 [Multi-domain]  Cd Length: 171  Bit Score: 62.72  E-value: 2.98e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1127884959   5 WTQEVIDRASRLWKDGKSAMEIAEEIG-VTRNSVLSIMHRyrelfpkLGITSRQ 57
Cdd:COG5352     3 WTDERVELLKKLWSEGLSASQIAAELGgVTRNAVIGKVHR-------LGLSGRA 49
 
Name Accession Description Interval E-value
COG5352 COG5352
Uncharacterized conserved protein [Function unknown];
5-57 2.98e-12

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 444133 [Multi-domain]  Cd Length: 171  Bit Score: 62.72  E-value: 2.98e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1127884959   5 WTQEVIDRASRLWKDGKSAMEIAEEIG-VTRNSVLSIMHRyrelfpkLGITSRQ 57
Cdd:COG5352     3 WTDERVELLKKLWSEGLSASQIAAELGgVTRNAVIGKVHR-------LGLSGRA 49
GcrA pfam07750
GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see ...
 5-58 3.29e-07

GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see pfam00072 and pfam00486), is involved in controlling cell cycle progression and asymmetric polar morphogenesis. During this process, there are temporal and spatial variations in the concentrations of GcrA and CtrA. The variation in concentration produces time and space dependent transcriptional regulation of modular functions that implement cell-cycle processes. More specifically, GcrA acts as an activator of components of the replisome and the segregation machinery.


Pssm-ID: 400210 [Multi-domain]  Cd Length: 155  Bit Score: 48.23  E-value: 3.29e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1127884959   5 WTQEVIDRASRLWKDGKSAMEIAEEIG-VTRNSVLSIMHRyrelfpkLGITSRQA 58
Cdd:pfam07750   3 WTDERVETLKKLWLEGLSASQIAAQLGgVSRNAVIGKVHR-------LGLSGRAK 50
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 15-59 2.15e-03

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 35.20  E-value: 2.15e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1127884959   15 RLWKDGKSAMEIAEEIGVTRNSVLSimHRYReLFPKLGITSR-QAI 59
Cdd:smart00421  13 RLLAEGLTNKEIAERLGISEKTVKT--HLSN-IMRKLGVRSRtQAV 55
 
Name Accession Description Interval E-value
COG5352 COG5352
Uncharacterized conserved protein [Function unknown];
5-57 2.98e-12

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 444133 [Multi-domain]  Cd Length: 171  Bit Score: 62.72  E-value: 2.98e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1127884959   5 WTQEVIDRASRLWKDGKSAMEIAEEIG-VTRNSVLSIMHRyrelfpkLGITSRQ 57
Cdd:COG5352     3 WTDERVELLKKLWSEGLSASQIAAELGgVTRNAVIGKVHR-------LGLSGRA 49
GcrA pfam07750
GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see ...
 5-58 3.29e-07

GcrA cell cycle regulator; GcrA is a master cell cycle regulator that, together with CtrA (see pfam00072 and pfam00486), is involved in controlling cell cycle progression and asymmetric polar morphogenesis. During this process, there are temporal and spatial variations in the concentrations of GcrA and CtrA. The variation in concentration produces time and space dependent transcriptional regulation of modular functions that implement cell-cycle processes. More specifically, GcrA acts as an activator of components of the replisome and the segregation machinery.


Pssm-ID: 400210 [Multi-domain]  Cd Length: 155  Bit Score: 48.23  E-value: 3.29e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1127884959   5 WTQEVIDRASRLWKDGKSAMEIAEEIG-VTRNSVLSIMHRyrelfpkLGITSRQA 58
Cdd:pfam07750   3 WTDERVETLKKLWLEGLSASQIAAQLGgVSRNAVIGKVHR-------LGLSGRAK 50
CitB COG2197
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ...
 15-65 8.44e-05

DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 441799 [Multi-domain]  Cd Length: 131  Bit Score: 41.03  E-value: 8.44e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1127884959  15 RLWKDGKSAMEIAEEIGVTRNSVLSimHRYReLFPKLGITSRQ-----AIERGLID 65
Cdd:COG2197    79 RLLAEGLSNKEIAERLGISERTVKT--HVSN-ILRKLGVRNRTelvllALRLGLLD 131
CsgD COG2771
DNA-binding transcriptional regulator, CsgD family [Transcription];
15-64 2.02e-04

DNA-binding transcriptional regulator, CsgD family [Transcription];


Pssm-ID: 442052 [Multi-domain]  Cd Length: 188  Bit Score: 40.89  E-value: 2.02e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1127884959  15 RLWKDGKSAMEIAEEIGVTRNSVLSimHRYReLFPKLGITSRQ-----AIERGLI 64
Cdd:COG2771   137 RLLAEGLTLKEIARILGISERTVRT--HLKR-IYRKLGVSSRAelvalALRLGLI 188
MalT COG2909
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
13-65 2.46e-04

ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];


Pssm-ID: 442153 [Multi-domain]  Cd Length: 184  Bit Score: 40.46  E-value: 2.46e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1127884959  13 ASRLWKDGKSAMEIAEEIGVTRNSVLSIMHRyreLFPKLGITSR-QAIER----GLID 65
Cdd:COG2909   130 RRRLLAEGLSNKEIAERLFISVNTVKTHLRN---IYRKLGVRSRtEAVARarelGLLA 184
HTH_LUXR smart00421
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
 15-59 2.15e-03

helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon


Pssm-ID: 197715 [Multi-domain]  Cd Length: 58  Bit Score: 35.20  E-value: 2.15e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1127884959   15 RLWKDGKSAMEIAEEIGVTRNSVLSimHRYReLFPKLGITSR-QAI 59
Cdd:smart00421  13 RLLAEGLTNKEIAERLGISEKTVKT--HLSN-IMRKLGVRSRtQAV 55
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 12-46 3.60e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 34.49  E-value: 3.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1127884959  12 RASRLWKDGKSAMEIAEEIGVTRNSVLSIMHRYRE 46
Cdd:pfam13518   4 KIVLLALEGESIKEAARLFGISRSTVYRWIRRYRE 38
HTH_23 pfam13384
Homeodomain-like domain;
12-46 5.26e-03

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 34.17  E-value: 5.26e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1127884959  12 RASRLWKDGKSAMEIAEEIGVTRNSVLSIMHRYRE 46
Cdd:pfam13384   9 RALLLLAEGLSVKEIAELLGVSRRTVYRWLKRYNE 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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