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Conserved domains on  [gi|1127547001|gb|APS24118|]
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rev protein [synthetic HIV-2]

Protein Classification

REV protein( domain architecture ID 140)

REV protein escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells

CATH:  1.10.287.2030
Gene Ontology:  GO:0003700|GO:0006355|GO:0051028|GO:0003723|GO:0016032
PubMed:  2550674|2656990|2741343

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
REV super family cl02864
REV protein (anti-repression trans-activator protein);
1-89 5.54e-23

REV protein (anti-repression trans-activator protein);


The actual alignment was detected with superfamily member pfam00424:

Pssm-ID: 366091  Cd Length: 91  Bit Score: 84.62  E-value: 5.54e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127547001   1 MNERAD--EEGLQRKLRLIRLLHQTNPYPQGPGTASQRRNRRRRWKQRWRQILALADSIYTFPDPPADSPLDQTIQHLQG 78
Cdd:pfam00424   1 MAGRSGdsDEGLQGKVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILATYLGRSAEPVPLQLPPLER 80

                          90
                  ....*....|.
gi 1127547001  79 LTIQELPDPPT 89
Cdd:pfam00424  81 LTLDCNEDCGT 91
 
Name Accession Description Interval E-value
REV pfam00424
REV protein (anti-repression trans-activator protein);
1-89 5.54e-23

REV protein (anti-repression trans-activator protein);


Pssm-ID: 366091  Cd Length: 91  Bit Score: 84.62  E-value: 5.54e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127547001   1 MNERAD--EEGLQRKLRLIRLLHQTNPYPQGPGTASQRRNRRRRWKQRWRQILALADSIYTFPDPPADSPLDQTIQHLQG 78
Cdd:pfam00424   1 MAGRSGdsDEGLQGKVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILATYLGRSAEPVPLQLPPLER 80

                          90
                  ....*....|.
gi 1127547001  79 LTIQELPDPPT 89
Cdd:pfam00424  81 LTLDCNEDCGT 91
 
Name Accession Description Interval E-value
REV pfam00424
REV protein (anti-repression trans-activator protein);
1-89 5.54e-23

REV protein (anti-repression trans-activator protein);


Pssm-ID: 366091  Cd Length: 91  Bit Score: 84.62  E-value: 5.54e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127547001   1 MNERAD--EEGLQRKLRLIRLLHQTNPYPQGPGTASQRRNRRRRWKQRWRQILALADSIYTFPDPPADSPLDQTIQHLQG 78
Cdd:pfam00424   1 MAGRSGdsDEGLQGKVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILATYLGRSAEPVPLQLPPLER 80

                          90
                  ....*....|.
gi 1127547001  79 LTIQELPDPPT 89
Cdd:pfam00424  81 LTLDCNEDCGT 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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