|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
4-419 |
0e+00 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 656.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 4 NLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEI 83
Cdd:PRK13342 1 PLAERMRPKTLDEVVGQEHLLGPGKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGATDAPFEALSAVTSGVKDLREV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 84 SEEAK----FSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEAL 159
Cdd:PRK13342 81 IEEARqrrsAGRRTILFIDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNPALLSRAQVFELKPLSEEDIEQLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 160 QIALSNPERGFdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVLStpendegIRHITLDIMENSLQRSYITMDKDGDGH 239
Cdd:PRK13342 161 KRALEDKERGL---VELDDEALDALARLANGDARRALNLLELAALG-------VDSITLELLEEALQKRAARYDKDGDEH 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 240 YDVLSALQKSIRGSDVDASLHYAARLIEAG-DLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIAN 318
Cdd:PRK13342 231 YDLISALHKSIRGSDPDAALYYLARMLEAGeDPLFIARRLVIIASEDIGLADPNALQVAVAAADAVERIGMPEGRIALAQ 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 319 VVIDLALSPKSNSAYVAMDKALTDLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYF 398
Cdd:PRK13342 311 AVIYLALAPKSNAAYTAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPNGYVGQQYLPDELKGKRYY 390
|
410 420
....*....|....*....|.
gi 1112991871 399 QAEDTGkYERALAQRKEAIDR 419
Cdd:PRK13342 391 EPTERG-FEKKIKERLEKLKD 410
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
5-422 |
0e+00 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 634.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIS 84
Cdd:COG2256 15 LAERMRPRTLDEVVGQEHLLGPGKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANATDAEFVALSAVTSGVKDIREVI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 85 EEAK----FSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ 160
Cdd:COG2256 95 EEARerraYGRRTILFVDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNSALLSRCRVFVLKPLSEEDLEQLLE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 161 IALSNPERGF-DFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENdeGIRHITLDIMENSLQRSYITMDKDGDGH 239
Cdd:COG2256 175 RALADDERGLgGYKLELDDEALEALARLADGDARRALNALELAVLSAPPD--GVIEITLELVEEALQRRALRYDKDGDEH 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 240 YDVLSALQKSIRGSDVDASLHYAARLIEAG-DLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIAN 318
Cdd:COG2256 253 YDLISAFIKSIRGSDPDAALYWLARMLEAGeDPRFIARRLVIMASEDIGLADPQALQIAVAAAQAVERLGMPEGRIALAQ 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 319 VVIDLALSPKSNSAYVAMDKALTDLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYF 398
Cdd:COG2256 333 AVIYLATAPKSNAAYLAINAALADVREGGSLPVPLHLRNAPTKLMKELGYGKGYKYPHDYPGGYVGQQYLPDELKGRRYY 412
|
410 420
....*....|....*....|....
gi 1112991871 399 QAEDTGkYERALAQRKEAIDRLRK 422
Cdd:COG2256 413 EPTERG-FERKIKERLEKLRKLRR 435
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
5-421 |
3.37e-132 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 396.73 E-value: 3.37e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIS 84
Cdd:PRK13341 18 LADRLRPRTLEEFVGQDHILGEGRLLRRAIKADRVGSLILYGPPGVGKTTLARIIANHTRAHFSSLNAVLAGVKDLRAEV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 85 EEAK-----FSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEAL 159
Cdd:PRK13341 98 DRAKerlerHGKRTILFIDEVHRFNKAQQDALLPWVENGTITLIGATTENPYFEVNKALVSRSRLFRLKSLSDEDLHQLL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 160 QIALSNPERGF-DFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITLDIMENSLQRSYITMDKDGDG 238
Cdd:PRK13341 178 KRALQDKERGYgDRKVDLEPEAEKHLVDVANGDARSLLNALELAVESTPPDEDGLIDITLAIAEESIQQRAVLYDKEGDA 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 239 HYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPS-LARRLTVIAYEDIGLANPEAqIHTVTALDAA-QKIGFPEARILI 316
Cdd:PRK13341 258 HFDTISAFIKSLRGSDPDAALYWLARMVEAGEDPRfIFRRMLIAASEDVGLADPQA-LVVVEACAAAfERVGLPEGLYPL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 317 ANVVIDLALSPKSNSAYVAMDkALTDLKTSGHLPIPRHLRDGHYSGsKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHH 396
Cdd:PRK13341 337 AQAALYLATAPKSNSVLGFFD-ALKKVREEQVQDVPNHLRDANRDG-KAFGDGVGYRYPHAFRDHWVAQQYLPEALQGEV 414
|
410 420
....*....|....*....|....*
gi 1112991871 397 YFQAEDTGkYEralAQRKEAIDRLR 421
Cdd:PRK13341 415 FWQPSRQG-WE---GERRERLARRR 435
|
|
| MgsA_C |
pfam12002 |
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA ... |
252-409 |
1.12e-84 |
|
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication. Additionally, MgsA may play a role in chromosomal segregation. This is consistent with a report that MgsA co-localizes with the replisome and affects chromosome segregation. This domain represents the C terminal region of MgsA.
Pssm-ID: 463426 [Multi-domain] Cd Length: 158 Bit Score: 255.73 E-value: 1.12e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 252 GSDVDASLHYAARLIEAG-DLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSN 330
Cdd:pfam12002 1 GSDPDAALYWLARMLEAGeDPLFIARRLVIIASEDIGLADPQALVVAVAAAQAVERIGMPEARIPLAQAVIYLALAPKSN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 331 SAYVAMDKALTDLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYFQAEDTGkYERA 409
Cdd:pfam12002 81 SAYLAIDAALADVREGGSLPVPLHLRNAPTKLMKKLGYGKGYKYPHDYPNGYVKQQYLPDELKGRRYYEPTDNG-YEKK 158
|
|
| PRK14700 |
PRK14700 |
recombination factor protein RarA; Provisional |
112-423 |
5.94e-55 |
|
recombination factor protein RarA; Provisional
Pssm-ID: 173163 [Multi-domain] Cd Length: 300 Bit Score: 184.06 E-value: 5.94e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 112 LPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPIELDEDALDFIATSTNGD 191
Cdd:PRK14700 1 MPYVESGKIILIGATTENPTYYLNDALVSRLFILRLKRLSLVATQKLIEKALSQDEVLAKHKFKIDDGLYNAMHNYNEGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 192 LRSAFNSLDLAVLSTPENDEgiRHITLDIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDL 271
Cdd:PRK14700 81 CRKILNLLERMFLISTRGDE--IYLNKELFDQAVGETSRDFHREGKEFYEQLSAFHKSVRGTDPDAAIFWLSVMLDNGVD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 272 P-SLARRLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYVAMDKALTDLKTSGHLP 350
Cdd:PRK14700 159 PlVIARRMLCIASEDIGNADPQALRVAMDAWNAYEKLGMPEGRLVLAQAAIYLAVAPKSNACYKALAQAQQLVKSLGNID 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1112991871 351 IPRHLRDghYSGSkelgnaqDYLYPHNYPGNWVKQDYLPEKIRnHHYFQAEDTGkYERALAQRKEAIDRLRKI 423
Cdd:PRK14700 239 VPQHLKN--YKDS-------NYLYPHNYPNSYVIQQYLPDNII-QNFYQPTASG-FEAKIKTKLDSINKIKKL 300
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
173-251 |
2.33e-31 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 114.49 E-value: 2.33e-31
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 173 PIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDeGIRHITLDIMENSLQRSYITMDKDGDGHYDVLSALQKSIR 251
Cdd:pfam16193 4 KIELDDEALEALAELADGDARRALNALELAVLSTPPDD-GGIHITLEILEEALQRKALRYDKDGDEHYDLISAFHKSIR 81
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
10-256 |
3.76e-22 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 98.07 E-value: 3.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEhlvgpgKIIRRMVE-ANRLSS------MILYGPPGIGKTSIASAIAGTtkYAFRTF--NAtvdSKKR- 79
Cdd:PRK04195 9 RPKTLSDVVGNE------KAKEQLREwIESWLKgkpkkaLLLYGPPGVGKTSLAHALAND--YGWEVIelNA---SDQRt 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 80 ---LQEISEEAKFSGGL------VLLLDE---IHR-------------LDKTKQdfllPllesglVIMigatTENPFFSV 134
Cdd:PRK04195 78 advIERVAGEAATSGSLfgarrkLILLDEvdgIHGnedrggarailelIKKAKQ----P------IIL----TANDPYDP 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 135 TPA-IRSRVQIFELEPLSNQDVKEALQ-IALSnpERgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVlstpendEG 212
Cdd:PRK04195 144 SLReLRNACLMIEFKRLSTRSIVPVLKrICRK--EG-----IECDDEALKEIAERSGGDLRSAINDLQAIA-------EG 209
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1112991871 213 IRHITLDIMENSLQRsyitmdkdgDGHYDVLSALQKSIRGSDVD 256
Cdd:PRK04195 210 YGKLTLEDVKTLGRR---------DREESIFDALDAVFKARNAD 244
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
150-226 |
1.30e-19 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 82.29 E-value: 1.30e-19
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1112991871 150 LSNQDVKEALQIALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENdeGIRHITLDIMENSLQ 226
Cdd:cd18139 1 LSEEDLEKLLKRALEDKERGGDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAEED--GGIVITLEDLEEVLQ 75
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
42-150 |
1.20e-18 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 81.49 E-value: 1.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNAT-------VDSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTK------- 107
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSelvskyvGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRgsggdse 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1112991871 108 ----QDFLLPLLE-----SGLVIMIGATTEnpFFSVTPAIRSRVQIFELEPL 150
Cdd:pfam00004 81 srrvVNQLLTELDgftssNSKVIVIAATNR--PDKLDPALLGRFDRIIEFPL 130
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
11-324 |
6.00e-18 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 84.47 E-value: 6.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 11 PKTIDQVIGQEHLVgpgKIIRRMVEANRLS-SMILYGPPGIGKTSIASAIAgttKYAF----------------RTFNA- 72
Cdd:COG2812 6 PQTFDDVVGQEHVV---RTLKNALASGRLAhAYLFTGPRGVGKTTLARILA---KALNcengptgepcgecescRAIAAg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 73 ---------------TVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLdkTKQDF--LLPLLE--SGLVIMIGATTEnpFF 132
Cdd:COG2812 80 shpdvieidaeasniGVDDIRELIEKVSYAPVEGRYkVYIIDEAHML--TTEAFnaLLKTLEepPPHVVFILATTE--PQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 133 SVTPAIRSRVQIFELEPLSNQDVKEALQIALSnpERGfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVLStpeNDEG 212
Cdd:COG2812 156 KLLPTILSRCQRFDFRRLPPEEIAEHLAKIAE--REG----IEIEPEALALIARAADGSMRDALSLLDQAIAF---GLLD 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 213 IRHITLDIMENSLQRsyitmdkdgdGHYDVLSALQKSIR-GSDVDASLHYAARLI-------EAGDLPSLARRLTVIAYE 284
Cdd:COG2812 227 RRELLLDLLEALLAG----------DVAALLALAEELAKrGRDLKRFLDDLLSLLrdllllkLGPDAELLVNEDERERLQ 296
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1112991871 285 DIGLANPEAQIHTV--TALDAAQKIGF-PEARILIANVVIDLA 324
Cdd:COG2812 297 ELARRLSPERLLRAiqILLEARRELERnVNPRLALEMLLLRLA 339
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
6-203 |
1.17e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 78.71 E-value: 1.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 6 ALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIAGT---------------------T 63
Cdd:PRK14953 7 ARKYRPKFFKEVIGQEIVV---RILKNAVKLQRVSHAYIFaGPRGTGKTTIARILAKVlnclnpqegepcgkcencveiD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 64 KYAFRTF-------NATVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEnpFFS 133
Cdd:PRK14953 84 KGSFPDLieidaasNRGIDDIRALRDAVSYTPIKGKYkVYIIDEAHMLTKEAFNALLKTLEEppPRTIFILCTTE--YDK 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 134 VTPAIRSRVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK14953 162 IPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEK------IEYEEKALDLLAQASEGGMRDAASLLDQAS 225
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
6-209 |
4.21e-15 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 76.07 E-value: 4.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 6 ALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIAGTTK----------YAFRTF---- 70
Cdd:PRK14970 8 ARKYRPQTFDDVVGQSHIT---NTLLNAIENNHLAQALLFcGPRGVGKTTCARILARKINqpgyddpnedFSFNIFelda 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 71 --NATVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTENpfFSVTPAIRSRVQIF 145
Cdd:PRK14970 85 asNNSVDDIRNLIDQVRIPPQTGKYkIYIIDEVHMLSSAAFNAFLKTLEEppAHAIFILATTEK--HKIIPTILSRCQIF 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1112991871 146 ELEPLSNQDVKEAL-QIALSNpergfdfPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPEN 209
Cdd:PRK14970 163 DFKRITIKDIKEHLaGIAVKE-------GIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKN 220
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
10-268 |
5.81e-15 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 75.29 E-value: 5.81e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILYGPPGIGKTSIASAIA----GTT-KYAFRTFNA-------TVDSK 77
Cdd:PRK00440 12 RPRTLDEIVGQEEIV---ERLKSYVKEKNMPHLLFAGPPGTGKTTAALALArelyGEDwRENFLELNAsdergidVIRNK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 78 krlqeISEEA--KFSGGL---VLLLDEIHRLDKTKQDFLLPLLEsglviMIGATTE-----NPFFSVTPAIRSRVQIFEL 147
Cdd:PRK00440 89 -----IKEFArtAPVGGApfkIIFLDEADNLTSDAQQALRRTME-----MYSQNTRfilscNYSSKIIDPIQSRCAVFRF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 148 EPLSNQDVKEALQ-IAlsnPERGfdfpIELDEDALDFIATSTNGDLRSAFNSLDLA-VLSTPENDEGIRHIT-------- 217
Cdd:PRK00440 159 SPLKKEAVAERLRyIA---ENEG----IEITDDALEAIYYVSEGDMRKAINALQAAaATGKEVTEEAVYKITgtarpeei 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 218 LDIMENSLQRSYIT--------MDKDGDGHYDVLSALQKSIRGSDVDASLhyAARLIEA 268
Cdd:PRK00440 232 REMIELALNGDFTEareklrdlMIDYGLSGEDIIKQIHREVWSLDIPEEL--KVELIDA 288
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
18-149 |
1.98e-14 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 70.25 E-value: 1.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 18 IGQEHLVgpgKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTF---------NATVDSKKR----LQEIS 84
Cdd:cd00009 1 VGQEEAI---EALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFlylnasdllEGLVVAELFghflVRLLF 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 85 EEAKFSGGLVLLLDEIHRLDKTKQDFLLPLLESGL--------VIMIGATTENPFFSVTPAIRSR-VQIFELEP 149
Cdd:cd00009 78 ELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNdlridrenVRVIGATNRPLLGDLDRALYDRlDIRIVIPL 151
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
5-333 |
3.03e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 71.66 E-value: 3.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRL-SSMILYGPPGIGKTSIASAIAGTtkyaFRTFNAT---------- 73
Cdd:PRK08691 6 LARKWRPKTFADLVGQEHVV---KALQNALDEGRLhHAYLLTGTRGVGKTTIARILAKS----LNCENAQhgepcgvcqs 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 74 ---VDSKK----------------RLQEISEEAKFSGGL----VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTE 128
Cdd:PRK08691 79 ctqIDAGRyvdlleidaasntgidNIREVLENAQYAPTAgkykVYIIDEVHMLSKSAFNAMLKTLEEppEHVKFILATTD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 129 NPFFSVTpaIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPieldedALDFIATSTNGDLRSAFNSLDLAVL---- 204
Cdd:PRK08691 159 PHKVPVT--VLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPP------ALQLLGRAAAGSMRDALSLLDQAIAlgsg 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 205 STPENDegIRHitldiMENSLQRSYItmdkdgdghYDVLSAlqksIRGSDVDASLHYAARLIEA--------GDLPSLAR 276
Cdd:PRK08691 231 KVAEND--VRQ-----MIGAVDKQYL---------YELLTG----IINQDGAALLAKAQEMAACavgfdnalGELAILLQ 290
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1112991871 277 RLTVIAYEDIGLANPEAQIHTVTALdaAQKIGfPEARILIANVVI----DLALSPKSNSAY 333
Cdd:PRK08691 291 QLALIQAVPSALAHDDPDSDILHRL--AQTIS-GEQIQLYYQIAVhgkrDLSLAPDEYAGF 348
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
8-305 |
3.05e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 71.41 E-value: 3.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 8 RMRPKTIDQVIGQEHLVGPgkiIRRMVEANRLSSMILY-GPPGIGKTSIASAIAGTTK---------------YAFR--- 68
Cdd:PRK14963 7 RARPITFDEVVGQEHVKEV---LLAALRQGRLGHAYLFsGPRGVGKTTTARLIAMAVNcsgedpkpcgecescLAVRrga 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 69 ---------TFNATVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTENPffSVTP 136
Cdd:PRK14963 84 hpdvleidaASNNSVEDVRDLREKVLLAPLRGGRkVYILDEAHMMSKSAFNALLKTLEEppEHVIFILATTEPE--KMPP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 137 AIRSRVQIFELEPLSNQDVKEALQIALSNPERgfdfpiELDEDALDFIATSTNGDLRSAFNSLD-LAVLSTPendegirh 215
Cdd:PRK14963 162 TILSRTQHFRFRRLTEEEIAGKLRRLLEAEGR------EAEPEALQLVARLADGAMRDAESLLErLLALGTP-------- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 216 ITLDIMENSLqrsyitmdkdGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLP-SLARRLTVI----AYEDIGLAN 290
Cdd:PRK14963 228 VTRKQVEEAL----------GLPPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAArTLVEGLLEAfraaLYAELGLGG 297
|
330 340
....*....|....*....|..
gi 1112991871 291 -------PEAQIHTVTALDAAQ 305
Cdd:PRK14963 298 gprlegaEPRLLAAMTALDEQM 319
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
6-209 |
4.12e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 70.96 E-value: 4.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 6 ALRMRPKTIDQVIGQEHLVGpgkIIRRMVEANRLSSMILY-GPPGIGKTSIASAIAGTTK-----------------YAF 67
Cdd:PRK14971 8 ARKYRPSTFESVVGQEALTT---TLKNAIATNKLAHAYLFcGPRGVGKTTCARIFAKTINcqnltadgeacnecescVAF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 68 ---RTFN------ATVDSKKRLQEISEEAKF---SGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTENpfF 132
Cdd:PRK14971 85 neqRSYNiheldaASNNSVDDIRNLIEQVRIppqIGKYkIYIIDEVHMLSQAAFNAFLKTLEEppSYAIFILATTEK--H 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1112991871 133 SVTPAIRSRVQIFELEPLSNQDVKEALQ-IALSNPergfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPEN 209
Cdd:PRK14971 163 KILPTILSRCQIFDFNRIQVADIVNHLQyVASKEG-------ITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGN 233
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
4-222 |
4.57e-13 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 70.58 E-value: 4.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 4 NLALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA--------------GTTK--YA 66
Cdd:PRK14964 2 NLALKYRPSSFKDLVGQDVLV---RILRNAFTLNKIPQSILLvGASGVGKTTCARIISlclncsngptsdpcGTCHncIS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 67 FRTF------------NATVDSKKRLQEISE----EAKFSgglVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTE 128
Cdd:PRK14964 79 IKNSnhpdvieidaasNTSVDDIKVILENSCylpiSSKFK---VYIIDEVHMLSNSAFNALLKTLEEpaPHVKFILATTE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 129 NPFFSVTpaIRSRVQIFELEPLSNQDVKEALQIaLSNPERgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAV----- 203
Cdd:PRK14964 156 VKKIPVT--IISRCQRFDLQKIPTDKLVEHLVD-IAKKEN-----IEHDEESLKLIAENSSGSMRNALFLLEQAAiysnn 227
|
250 260
....*....|....*....|....
gi 1112991871 204 -LSTPENDEGI----RHITLDIME 222
Cdd:PRK14964 228 kISEKSVRDLLgcvdKHILEDLVE 251
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
7-278 |
5.81e-13 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 69.63 E-value: 5.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 7 LRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILYGPPGIGKTSIASAIA---------------------GTTKY 65
Cdd:PRK12402 7 EKYRPALLEDILGQDEVV---ERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALArelygdpwennftefnvadffDQGKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 66 AFRT---FNATVDSKKR------------LQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLE--SGLVIMIGATT 127
Cdd:PRK12402 84 YLVEdprFAHFLGTDKRirsskidnfkhvLKEYASYRPLSADYkTILLDNAEALREDAQQALRRIMEqySRTCRFIIATR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 128 eNPfFSVTPAIRSR-VQIFeLEPLSNQDVKEALQ-IALSNpergfdfPIELDEDALDFIATSTNGDLRSAFNSLDLAVLS 205
Cdd:PRK12402 164 -QP-SKLIPPIRSRcLPLF-FRAPTDDELVDVLEsIAEAE-------GVDYDDDGLELIAYYAGGDLRKAILTLQTAALA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 206 TPEndegirhITLDIMENSLQRSYIT----------MDKDGDGHYDVLSALQ--KSIRGSDVDASLHYAARLIEAGD-LP 272
Cdd:PRK12402 234 AGE-------ITMEAAYEALGDVGTDevieslldaaEAGDFTDARKTLDDLLidEGLSGGEVLEELLRVARSRYRGDnLA 306
|
....*.
gi 1112991871 273 SLARRL 278
Cdd:PRK12402 307 RLHRLA 312
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
9-124 |
1.05e-12 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 65.60 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 9 MRPKTIDQVIGQEHLVGPGKIirrMVEANR-----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKR---- 79
Cdd:pfam05496 1 LRPRTLDEYIGQEKVKENLKI---FIEAAKqrgeaLDHVLLYGPPGLGKTTLANIIANEMGVNIRITSGPAIERPGdlaa 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1112991871 80 -LQEISEeakfsgGLVLLLDEIHRLDKTKQDFLLPLLESG-LVIMIG 124
Cdd:pfam05496 78 iLTNLEP------GDVLFIDEIHRLNRAVEEILYPAMEDFrLDIVIG 118
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
10-237 |
2.48e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 68.25 E-value: 2.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLvgpGKIIRRMVEANRLS-SMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISE--- 85
Cdd:PRK14962 9 RPKTFSEVVGQDHV---KKLIINALKKNSIShAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEgtf 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 86 ------EAKFSGGL--------------------VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTeNPfFSVTPA 137
Cdd:PRK14962 86 mdvielDAASNRGIdeirkirdavgyrpmegkykVYIIDEVHMLTKEAFNALLKTLEEppSHVVFVLATT-NL-EKVPPT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 138 IRSRVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLD-LAVLSTPENDEGIRHI 216
Cdd:PRK14962 164 IISRCQVIEFRNISDELIIKRLQEVAEAEG------IEIDREALSFIAKRASGGLRDALTMLEqVWKFSEGKITLETVHE 237
|
250 260
....*....|....*....|.
gi 1112991871 217 TLDIMENSLQRSYITMDKDGD 237
Cdd:PRK14962 238 ALGLIPIEVVRDYINAIFNGD 258
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
8-278 |
2.81e-12 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 68.30 E-value: 2.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 8 RMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIAG-----TTKYAFRTFN---------- 71
Cdd:PRK14950 9 KWRSQTFAELVGQEHVV---QTLRNAIAEGRVAHAYLFtGPRGVGKTSTARILAKavnctTNDPKGRPCGtcemcraiae 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 72 -----------ATVDSKKRLQEISEEAKFSGGL----VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEnpFFSV 134
Cdd:PRK14950 86 gsavdviemdaASHTSVDDAREIIERVQFRPALarykVYIIDEVHMLSTAAFNALLKTLEEppPHAIFILATTE--VHKV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 135 TPAIRSRVQIFELEPLSNQDVKEALQ-IALSNpergfdfPIELDEDALDFIATSTNGDLRSAFNSLD-LAVLSTPEndeg 212
Cdd:PRK14950 164 PATILSRCQRFDFHRHSVADMAAHLRkIAAAE-------GINLEPGALEAIARAATGSMRDAENLLQqLATTYGGE---- 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1112991871 213 irhITLDIMENSLqrsyitmdkdGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAG-DLPSLARRL 278
Cdd:PRK14950 233 ---ISLSQVQSLL----------GISGDEEVKALAEALLAKDLKAALRTLNAVAADGaDLRQFTRDL 286
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
6-219 |
3.18e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 68.26 E-value: 3.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 6 ALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA------------------------ 60
Cdd:PRK06647 7 ATKRRPRDFNSLEGQDFVV---ETLKHSIESNKIANAYIFsGPRGVGKTSSARAFArclncvngptpmpcgecsscksid 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 61 -GTTKYAFRTFNATVDSKKRLQEISEEAKF----SGGLVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEnpFFS 133
Cdd:PRK06647 84 nDNSLDVIEIDGASNTSVQDVRQIKEEIMFppasSRYRVYIIDEVHMLSNSAFNALLKTIEEppPYIVFIFATTE--VHK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 134 VTPAIRSRVQIFELEPLSNQDVKEALQIAlsnperGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPendegi 213
Cdd:PRK06647 162 LPATIKSRCQHFNFRLLSLEKIYNMLKKV------CLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSD------ 229
|
....*.
gi 1112991871 214 RHITLD 219
Cdd:PRK06647 230 SDITLE 235
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
5-327 |
1.54e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 65.92 E-value: 1.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA-------GTT------------- 63
Cdd:PRK14969 6 LARKWRPKSFSELVGQEHVV---RALTNALEQQRLHHAYLFtGTRGVGKTTLARILAkslncetGVTatpcgvcsaclei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 64 -KYAFRTF-------NATVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTENPFF 132
Cdd:PRK14969 83 dSGRFVDLievdaasNTQVDAMRELLDNAQYAPTRGRFkVYIIDEVHMLSKSAFNAMLKTLEEppEHVKFILATTDPQKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 133 SVTpaIRSRVQIFELEPLSNQDVKEALQIALSNpERgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVL--STPEND 210
Cdd:PRK14969 163 PVT--VLSRCLQFNLKQMPPPLIVSHLQHILEQ-EN-----IPFDATALQLLARAAAGSMRDALSLLDQAIAygGGTVNE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 211 EGIRhitldIMENSLQRSYItmdkdgdghYDVLSALQksirGSDVDASLHYAARLIEAG--------DLPSLARRLTV-- 280
Cdd:PRK14969 235 SEVR-----AMLGAIDQDYL---------FALLEALL----AQDGAALLAIADAMEERSlsfdaalqDLAALLHRLAIaq 296
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1112991871 281 IAYEDIGLANPEAQihtvTALDAAQKIGfPEARILIANVVI----DLALSP 327
Cdd:PRK14969 297 TVPDSIADDLPERD----RLLDLAKRLS-PEDIQLYYQIALhgrrDLGLAP 342
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
30-204 |
1.61e-11 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 64.61 E-value: 1.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 30 IRRMVEANRLS-SMILYGPPGIGKTSIASAIA--------------GTTKYA---------FRTFNATVDSKKR------ 79
Cdd:COG0470 8 LLAAAESGRLPhALLLHGPPGIGKTTLALALArdllcenpeggkacGQCHSRlmaagnhpdLLELNPEEKSDQIgidqir 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 80 --LQEISEEAKFSGGLVLLLDEIHRLDKTKQDFLLPLLE----SGLVIMIgatTENPfFSVTPAIRSRVQIFELEPLSNQ 153
Cdd:COG0470 88 elGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEeppkNTPFILI---ANDP-SRLLPTIRSRCQVIRFRPPSEE 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1112991871 154 DVKEALQialsnpERGfdfpieLDEDALDFIATSTNGDLRSAFNSLDLAVL 204
Cdd:COG0470 164 EALAWLR------EEG------VDEDALEAILRLAGGDPRAAINLLQALAG 202
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
12-255 |
2.11e-11 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 64.24 E-value: 2.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 12 KTIDQVIGQEhlvgpgKIIRRM---VEANR-----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKR---- 79
Cdd:TIGR00635 1 KLLAEFIGQE------KVKEQLqlfIEAAKmrqeaLDHLLLYGPPGLGKTTLAHIIANEMGVNLKITSGPALEKPGdlaa 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 80 -LQEISEeakfsgGLVLLLDEIHRLDKTKQDFLLPLLE------------SGLVI--------MIGATTEnpFFSVTPAI 138
Cdd:TIGR00635 75 iLTNLEE------GDVLFIDEIHRLSPAVEELLYPAMEdfrldivigkgpSARSVrldlppftLVGATTR--AGMLTSPL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 139 RSRVQI-FELEPLSNQDVKEALQIAlsnperGFDFPIELDEDALDFIATSTNGDLRSAFNSL----DLAVLstpendEGI 213
Cdd:TIGR00635 147 RDRFGIiLRLEFYTVEELAEIVSRS------AGLLNVEIEPEAALEIARRSRGTPRIANRLLrrvrDFAQV------RGQ 214
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1112991871 214 RHITLDIMENSLQRSYItmDKDGDGHYDV--LSALQKSIRGSDV 255
Cdd:TIGR00635 215 KIINRDIALKALEMLMI--DELGLDEIDRklLSVLIEQFQGGPV 256
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
10-200 |
3.00e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 65.22 E-value: 3.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLVGPGKIIrrmVEANRLSSMILY-GPPGIGKTSIASAIAGTTKYAFRT------------FNATVD- 75
Cdd:PRK07133 13 RPKTFDDIVGQDHIVQTLKNI---IKSNKISHAYLFsGPRGTGKTSVAKIFANALNCSHKTdllepcqecienVNNSLDi 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 76 ---------SKKRLQEISEEAKF----SGGLVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTENPFFSVTpaIRS 140
Cdd:PRK07133 90 iemdaasnnGVDEIRELIENVKNlptqSKYKIYIIDEVHMLSKSAFNALLKTLEEppKHVIFILATTEVHKIPLT--ILS 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 141 RVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLD 200
Cdd:PRK07133 168 RVQRFNFRRISEDEIVSRLEFILEKEN------ISYEKNALKLIAKLSSGSLRDALSIAE 221
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
9-185 |
8.37e-11 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 62.84 E-value: 8.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 9 MRPKTIDQVIGQEHLVGPGKIirrMVEANR-----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKR---- 79
Cdd:PRK00080 19 LRPKSLDEFIGQEKVKENLKI---FIEAAKkrgeaLDHVLLYGPPGLGKTTLANIIANEMGVNIRITSGPALEKPGdlaa 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 80 -LQEISEeakfsgGLVLLLDEIHRLDKTKQDFLLPLLESG-LVIMI-------------------GATTE-----NPFfs 133
Cdd:PRK00080 96 iLTNLEE------GDVLFIDEIHRLSPVVEEILYPAMEDFrLDIMIgkgpaarsirldlppftliGATTRaglltSPL-- 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 134 vtpaiRSRVQI-FELEPLSNQDVKEALQialsnpeRGFD-FPIELDEDALDFIA 185
Cdd:PRK00080 168 -----RDRFGIvQRLEFYTVEELEKIVK-------RSARiLGVEIDEEGALEIA 209
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
10-224 |
2.70e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 62.17 E-value: 2.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLVgpgKIIRRMVEANRLS-SMILYGPPGIGKTSIASAIAGttkyAFRTFN----------------- 71
Cdd:PRK05896 11 RPHNFKQIIGQELIK---KILVNAILNNKLThAYIFSGPRGIGKTSIAKIFAK----AINCLNpkdgdccnscsvcesin 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 72 ------------ATVDSKKRLQEISEEAKFSGGL----VLLLDEIHRLDKTKQDFLLPLLESG--LVIMIGATTEnpFFS 133
Cdd:PRK05896 84 tnqsvdiveldaASNNGVDEIRNIIDNINYLPTTfkykVYIIDEAHMLSTSAWNALLKTLEEPpkHVVFIFATTE--FQK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 134 VTPAIRSRVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLavLSTPENDEgi 213
Cdd:PRK05896 162 IPLTIISRCQRYNFKKLNNSELQELLKSIAKKEK------IKIEDNAIDKIADLADGSLRDGLSILDQ--LSTFKNSE-- 231
|
250
....*....|.
gi 1112991871 214 rhITLDIMENS 224
Cdd:PRK05896 232 --IDIEDINKT 240
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
42-205 |
4.68e-10 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 61.46 E-value: 4.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNATV-------DSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQDF---- 110
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGPEimskyygESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVtgev 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 111 -------LLPLL----ESGLVIMIGATteNPFFSVTPAIRsRVQIFELE----PLSNQDVKEALQIALSNpergfdFPIE 175
Cdd:TIGR01243 295 ekrvvaqLLTLMdglkGRGRVIVIGAT--NRPDALDPALR-RPGRFDREivirVPDKRARKEILKVHTRN------MPLA 365
|
170 180 190
....*....|....*....|....*....|
gi 1112991871 176 LDEDaLDFIATSTNGdlrsaFNSLDLAVLS 205
Cdd:TIGR01243 366 EDVD-LDKLAEVTHG-----FVGADLAALA 389
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
5-203 |
5.72e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 61.25 E-value: 5.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVGPgkiIRRMVEANRLSSMILY-GPPGIGKTSIASAIA-------GTT------------- 63
Cdd:PRK14957 6 LARKYRPQSFAEVAGQQHALNS---LVHALETQKVHHAYLFtGTRGVGKTTLGRLLAkclncktGVTaepcnkcencvai 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 64 -----------KYAFRT-FNATVDSKKRLQEISEEAKFSgglVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEN 129
Cdd:PRK14957 83 nnnsfidlieiDAASRTgVEETKEILDNIQYMPSQGRYK---VYLIDEVHMLSKQSFNALLKTLEEppEYVKFILATTDY 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 130 PFFSVTpaIRSRVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK14957 160 HKIPVT--ILSRCIQLHLKHISQADIKDQLKIILAKEN------INSDEQSLEYIAYHAKGSLRDALSLLDQAI 225
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
42-181 |
1.02e-09 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 58.74 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNATV-------DSKKRLQEISEEAKfSGGLVLLLDEIHRLDKTKQDF---- 110
Cdd:COG1223 38 ILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSligsylgETARNLRKLFDFAR-RAPCVIFFDEFDAIAKDRGDQndvg 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 111 --------LLPLLE---SGLVImIGATteNPFFSVTPAIRSRvqiFELE---PLSNqdvKEALQIALSNPERGFDFPIEL 176
Cdd:COG1223 117 evkrvvnaLLQELDglpSGSVV-IAAT--NHPELLDSALWRR---FDEViefPLPD---KEERKEILELNLKKFPLPFEL 187
|
....*
gi 1112991871 177 DEDAL 181
Cdd:COG1223 188 DLKKL 192
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
10-124 |
1.39e-09 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 59.32 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLVGPGKIirrMVEANR-----LSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKR----- 79
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKI---FIEAAKkrgeaLDHVLLYGPPGLGKTTLAHIIANEMGVNIRITSGPAIEKPGdlaai 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1112991871 80 ---LQEiseeakfsgGLVLLLDEIHRLDKTKQDFLLPLLESG-LVIMIG 124
Cdd:COG2255 100 ltnLEE---------GDVLFIDEIHRLSRVVEEILYPAMEDFrLDIVIG 139
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
5-203 |
1.55e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 59.05 E-value: 1.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLS-SMILYGPPGIGKTSIASAIA-------GTTKYAFRTFNATVD- 75
Cdd:PRK14961 6 LARKWRPQYFRDIIGQKHIV---TAISNGLSLGRIHhAWLLSGTRGVGKTTIARLLAkslncqnGITSNPCRKCIICKEi 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 76 --------------SKKRLQEISE----------EAKFSgglVLLLDEIHRLDKTKQDFLLPLLESG--LVIMIGATTEn 129
Cdd:PRK14961 83 ekglcldlieidaaSRTKVEEMREildniyyspsKSRFK---VYLIDEVHMLSRHSFNALLKTLEEPpqHIKFILATTD- 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 130 pFFSVTPAIRSRVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK14961 159 -VEKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKES------IDTDEYALKLIAYHAHGSMRDALNLLEHAI 225
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
6-231 |
2.42e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 59.10 E-value: 2.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 6 ALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLS-SMILYGPPGIGKTSIASAIAG--------TTKYAFRT------- 69
Cdd:PRK06645 12 ARKYRPSNFAELQGQEVLV---KVLSYTILNDRLAgGYLLTGIRGVGKTTSARIIAKavncsaliTENTTIKTceqctnc 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 70 --FN---------------ATVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEN 129
Cdd:PRK06645 89 isFNnhnhpdiieidaaskTSVDDIRRIIESAEYKPLQGKHkIFIIDEVHMLSKGAFNALLKTLEEppPHIIFIFATTEV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 130 PFFSVTpaIRSRVQIFELEPLSNQDVKEALQ--IALSNpergfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTP 207
Cdd:PRK06645 169 QKIPAT--IISRCQRYDLRRLSFEEIFKLLEyiTKQEN--------LKTDIEALRIIAYKSEGSARDAVSILDQAASMSA 238
|
250 260
....*....|....*....|....
gi 1112991871 208 ENDEGIRHITLDIMENSLQRSYIT 231
Cdd:PRK06645 239 KSDNIISPQVINQMLGLVDSSVII 262
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
5-203 |
7.91e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 57.75 E-value: 7.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLvgpGKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA-------GTTKY----------- 65
Cdd:PRK14960 5 LARKYRPRNFNELVGQNHV---SRALSSALERGRLHHAYLFtGTRGVGKTTIARILAkclncetGVTSTpcevcatckav 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 66 -------------AFRTfnATVDSKKRLQEIS---EEAKFSgglVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATT 127
Cdd:PRK14960 82 negrfidlieidaASRT--KVEDTRELLDNVPyapTQGRFK---VYLIDEVHMLSTHSFNALLKTLEEppEHVKFLFATT 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1112991871 128 ENPFFSVTpaIRSRVQIFELEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK14960 157 DPQKLPIT--VISRCLQFTLRPLAVDEITKHLGAILEKEQ------IAADQDAIWQIAESAQGSLRDALSLTDQAI 224
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
10-269 |
1.16e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 56.80 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA---------------------GTTKyaf 67
Cdd:PRK05563 11 RPQTFEDVVGQEHIT---KTLKNAIKQGKISHAYLFsGPRGTGKTSAAKIFAkavnclnppdgepcneceickAITN--- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 68 rtfNATVD-------SKKRLQEISE----------EAKFSgglVLLLDEIHRLdkTKQDF--LLPLLE--SGLVIMIGAT 126
Cdd:PRK05563 85 ---GSLMDvieidaaSNNGVDEIRDirdkvkyapsEAKYK---VYIIDEVHML--STGAFnaLLKTLEepPAHVIFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 127 TEN---PffsVTpaIRSRVQIFELEPLSNQDVKEALQIALSnpERGfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAv 203
Cdd:PRK05563 157 TEPhkiP---AT--ILSRCQRFDFKRISVEDIVERLKYILD--KEG----IEYEDEALRLIARAAEGGMRDALSILDQA- 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1112991871 204 LSTPENdegirHITLDIMENslqrsyITmdkdGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAG 269
Cdd:PRK05563 225 ISFGDG-----KVTYEDALE------VT----GSVSQEALDDLVDAIVEGDVAKALKILEELLDEG 275
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
42-232 |
1.27e-08 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 56.46 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFN-ATVDSK------KRLQEISEEAKFSGGLVLLLDEIHRL----DKTKQDF 110
Cdd:COG0464 194 LLLYGPPGTGKTLLARALAGELGLPLIEVDlSDLVSKyvgeteKNLREVFDKARGLAPCVLFIDEADALagkrGEVGDGV 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 111 -------LLPLLE--SGLVIMIGATteNPFFSVTPAIRSRVQ-IFELEPLSNQDVKEALQIALsnPERGFDFPIELDE-- 178
Cdd:COG0464 274 grrvvntLLTEMEelRSDVVVIAAT--NRPDLLDPALLRRFDeIIFFPLPDAEERLEIFRIHL--RKRPLDEDVDLEEla 349
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 179 DALDFIatsTNGDLRSAFNSLDLAVLStpendEGIRHITLDIMENSLQRSYITM 232
Cdd:COG0464 350 EATEGL---SGADIRNVVRRAALQALR-----LGREPVTTEDLLEALEREDIFL 395
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
8-146 |
2.49e-08 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 55.00 E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 8 RMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILYGP-PGIGKTSIASAIAGTTKYAFRTFNAtvdSKKRLQEISEE 86
Cdd:PHA02544 14 KYRPSTIDECILPAADK---ETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEVGAEVLFVNG---SDCRIDFVRNR 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1112991871 87 AK--------FSGGLVLLLDEIHRLD-KTKQDFLLPLLE--SGLVIMIgaTTENPFFSVTPAIRSRVQIFE 146
Cdd:PHA02544 88 LTrfastvslTGGGKVIIIDEFDRLGlADAQRHLRSFMEaySKNCSFI--ITANNKNGIIEPLRSRCRVID 156
|
|
| RecA-like_CDC48_r1-like |
cd19519 |
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ... |
42-139 |
4.99e-08 |
|
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410927 [Multi-domain] Cd Length: 166 Bit Score: 52.44 E-value: 4.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNATV-------DSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQDF---- 110
Cdd:cd19519 37 ILLYGPPGTGKTLIARAVANETGAFFFLINGPEimsklagESESNLRKAFEEAEKNAPAIIFIDEIDAIAPKREKThgev 116
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1112991871 111 -------LLPLLE----SGLVIMIGATteNPFFSVTPAIR 139
Cdd:cd19519 117 errivsqLLTLMDglkqRAHVIVMAAT--NRPNSIDPALR 154
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
43-139 |
9.62e-08 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 51.52 E-value: 9.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 43 ILYGPPGIGKTSIASAIAGTTKYAFRTFNATV-------DSKKRLQEISEEAKFSGGLVLLLDEI-----------HRLD 104
Cdd:cd19503 38 LLHGPPGTGKTLLARAVANEAGANFLSISGPSivskylgESEKNLREIFEEARSHAPSIIFIDEIdalapkreedqREVE 117
|
90 100 110
....*....|....*....|....*....|....*....
gi 1112991871 105 KTKQDFLLPLL----ESGLVIMIGATteNPFFSVTPAIR 139
Cdd:cd19503 118 RRVVAQLLTLMdgmsSRGKVVVIAAT--NRPDAIDPALR 154
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
40-101 |
1.15e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 51.13 E-value: 1.15e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 40 SSMILYGPPGIGKTSIASAIAGTTKYAFRTFNAT-------VDSKKRLQEISEEAKFSGGLVLLLDEIH 101
Cdd:cd19481 27 KGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSsllskyvGESEKNLRKIFERARRLAPCILFIDEID 95
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
13-227 |
1.63e-07 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 52.70 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 13 TIDQVIGQEHLVgpgKIIRRMVE-----ANRL--------SSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATV----- 74
Cdd:COG1222 76 TFDDIGGLDEQI---EEIREAVElplknPELFrkygieppKGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSElvsky 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 75 --DSKKRLQEISEEAKFSGGLVLLLDEI-----HRLDKTK----QDFLLPLL-------ESGLVIMIGATteNPFFSVTP 136
Cdd:COG1222 153 igEGARNVREVFELAREKAPSIIFIDEIdaiaaRRTDDGTsgevQRTVNQLLaeldgfeSRGDVLIIAAT--NRPDLLDP 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 137 AIR--SRV-QIFELEPLSNQDVKEALQIALSnpergfDFPIELDEDaLDFIATSTNG----DLRSAFNSLDLAVLStpen 209
Cdd:COG1222 231 ALLrpGRFdRVIEVPLPDEEAREEILKIHLR------DMPLADDVD-LDKLAKLTEGfsgaDLKAIVTEAGMFAIR---- 299
|
250
....*....|....*...
gi 1112991871 210 dEGIRHITLDIMENSLQR 227
Cdd:COG1222 300 -EGRDTVTMEDLEKAIEK 316
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
42-148 |
5.22e-07 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 49.33 E-value: 5.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNATV-------DSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQ------ 108
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGELKVPFLKISATEivsgvsgESEEKIRELFDQAISNAPCIVFIDEIDAITPKREsaqrem 116
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1112991871 109 -------------DFLLPLLESGLVIMIGATTENPffSVTPAIRsRVQIFELE 148
Cdd:cd19518 117 errivsqlltcmdELNNEKTAGGPVLVIGATNRPD--SLDPALR-RAGRFDRE 166
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
5-203 |
9.70e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 50.80 E-value: 9.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLvgpGKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA--------------GTTKYAFRT 69
Cdd:PRK08451 4 LALKYRPKHFDELIGQESV---SKTLSLALDNNRLAHAYLFsGLRGSGKTSSARIFAralvceqgpsstpcDTCIQCQSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 70 FN-----------ATVDSKKRLQEISEEAKFSGGL----VLLLDEIHRLdkTKQDF--LLPLLES--GLVIMIGATTEnP 130
Cdd:PRK08451 81 LEnrhidiiemdaASNRGIDDIRELIEQTKYKPSMarfkIFIIDEVHML--TKEAFnaLLKTLEEppSYVKFILATTD-P 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 131 FfsVTPA-IRSRVQIFELEPLSNQDVKEALQIALsNPERgfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK08451 158 L--KLPAtILSRTQHFRFKQIPQNSIISHLKTIL-EKEG-----VSYEPEALEILARSGNGSLRDTLTLLDQAI 223
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
38-135 |
7.55e-06 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.44 E-value: 7.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 38 RLSSMILYGPPGIGKTSIASAIAGTTKYAFRTF------------------------NATVDSKKRLQEISEEAKFSGGL 93
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGViyidgedileevldqllliivggkKASGSGELRLRLALALARKLKPD 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1112991871 94 VLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVT 135
Cdd:smart00382 81 VLILDEITSLLDAEQEALLLLLEELRLLLLLKSEKNLTVILT 122
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
43-100 |
9.43e-06 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 45.35 E-value: 9.43e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1112991871 43 ILYGPPGIGKTSIASAIAGTTKYAF------RTFNATV-DSKKRLQEISEEAKFSGGLVLLLDEI 100
Cdd:cd19511 31 LLYGPPGCGKTLLAKALASEAGLNFisvkgpELFSKYVgESERAVREIFQKARQAAPCIIFFDEI 95
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
28-222 |
1.05e-05 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 46.48 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 28 KIIRRMVEANRLSSM-ILYGPPGIGKTSIASAIAGTTKYAFR-TFNATVDSKKRLQEISEEAKFSGGL------------ 93
Cdd:COG2842 38 RFAEALDEARALPGIgVVYGESGVGKTTAAREYANRNPNVIYvTASPSWTSKELLEELAEELGIPAPPgtiadlrdrile 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 94 -------VLLLDEIHRLDKTKQDFLLPLLE-SGL-VIMIGatteNPffSVTPAIRSRVQIF-------ELEPLSNQDVKE 157
Cdd:COG2842 118 rlagtgrLLIIDEADHLKPKALEELRDIHDeTGVgVVLIG----ME--RLPAKLKRYEQLYsrigfwvEFKPLSLEDVRA 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1112991871 158 ALQIALsnpergfDFPielDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENdeGIRHITLDIME 222
Cdd:COG2842 192 LAEAWG-------ELT---DPDLLELLHRITRGNLRRLDRTLRLAARAAKRN--GLTKITLDHVR 244
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
10-199 |
2.59e-05 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 45.88 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 10 RPKTIDQVIGQEHLVGPgkiIRRMVEANRLSSMILYGPPGIGKTSIASAIA----GTT-KYAFRTFNATVD--------- 75
Cdd:PLN03025 8 RPTKLDDIVGNEDAVSR---LQVIARDGNMPNLILSGPPGTGKTTSILALAhellGPNyKEAVLELNASDDrgidvvrnk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 76 ----SKKRLQEISEEAKfsgglVLLLDEIHRLDKTKQDFLLPLLEsglviMIGATTE-----NPFFSVTPAIRSRVQIFE 146
Cdd:PLN03025 85 ikmfAQKKVTLPPGRHK-----IVILDEADSMTSGAQQALRRTME-----IYSNTTRfalacNTSSKIIEPIQSRCAIVR 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1112991871 147 LEPLSNQDVKEALQIALSNPErgfdfpIELDEDALDFIATSTNGDLRSAFNSL 199
Cdd:PLN03025 155 FSRLSDQEILGRLMKVVEAEK------VPYVPEGLEAIIFTADGDMRQALNNL 201
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
5-200 |
3.59e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 45.89 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA----------------------- 60
Cdd:PRK14965 6 LARKYRPQTFSDLTGQEHVS---RTLQNAIDTGRVAHAFLFtGARGVGKTSTARILAkalnceqgltaepcnvcppcvei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 61 --GTTKYAFR---TFNATVDSkkrLQEISEEAKF----SGGLVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEN 129
Cdd:PRK14965 83 teGRSVDVFEidgASNTGVDD---IRELRENVKYlpsrSRYKIFIIDEVHMLSTNAFNALLKTLEEppPHVKFIFATTEP 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1112991871 130 PFFSVTpaIRSRVQIFELEPLSNQDVKEAL-QIAlsnPERGfdfpIELDEDALDFIATSTNGDLRSAFNSLD 200
Cdd:PRK14965 160 HKVPIT--ILSRCQRFDFRRIPLQKIVDRLrYIA---DQEG----ISISDAALALVARKGDGSMRDSLSTLD 222
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
4-160 |
5.20e-05 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 45.43 E-value: 5.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 4 NLALRMRPKTIDQVIGQEhlvgpgKIIRRMVEA---NRLSSMILYGPPGIGKTSIASaiagttKYAFRTFN----ATVDS 76
Cdd:CHL00095 168 NLTKEAIDGNLDPVIGRE------KEIERVIQIlgrRTKNNPILIGEPGVGKTAIAE------GLAQRIVNrdvpDILED 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 77 KK---------------------RLQEISEEAKFSGGLVLLLDEIHRL--------DKTKQDFLLPLLESGLVIMIGATT 127
Cdd:CHL00095 236 KLvitldiglllagtkyrgefeeRLKRIFDEIQENNNIILVIDEVHTLigagaaegAIDAANILKPALARGELQCIGATT 315
|
170 180 190
....*....|....*....|....*....|....*.
gi 1112991871 128 ENPF---FSVTPAIRSRVQIFELEPLSNQDVKEALQ 160
Cdd:CHL00095 316 LDEYrkhIEKDPALERRFQPVYVGEPSVEETIEILF 351
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
5-208 |
5.42e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 45.15 E-value: 5.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA----------------------- 60
Cdd:PRK06305 7 SSRKYRPQTFSEILGQDAVV---AVLKNALRFNRAAHAYLFsGIRGTGKTTLARIFAkalncqnptedqepcnqcascke 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 61 ---GTTKYAFRTFNATVDSKKRLQEISEEAKFSGGL----VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTENpf 131
Cdd:PRK06305 84 issGTSLDVLEIDGASHRGIEDIRQINETVLFTPSKsrykIYIIDEVHMLTKEAFNSLLKTLEEppQHVKFFLATTEI-- 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1112991871 132 FSVTPAIRSRVQIFELEPLSNQDVKEALqiALSNPERGfdfpIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPE 208
Cdd:PRK06305 162 HKIPGTILSRCQKMHLKRIPEETIIDKL--ALIAKQEG----IETSREALLPIARAAQGSLRDAESLYDYVVGLFPK 232
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
8-141 |
1.21e-04 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 44.10 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 8 RMRPKTIDQVIGQEHLVGPGKIirrMVEANRLSSMILY-GPPGIGKTSIASAIA-------GTTKYAFRTFNATVD---- 75
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSS---ALDAGRINHAYLFsGPRGCGKTSSARILArslncaqGPTATPCGVCESCVAlapn 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 76 SKKRLQEISEEAKFSGGL--------------------VLLLDEIHRLdkTKQDF--LLPLLES--GLVIMIGATTENPf 131
Cdd:PRK14952 83 GPGSIDVVELDAASHGGVddtrelrdrafyapaqsryrIFIVDEAHMV--TTAGFnaLLKIVEEppEHLIFIFATTEPE- 159
|
170
....*....|
gi 1112991871 132 fSVTPAIRSR 141
Cdd:PRK14952 160 -KVLPTIRSR 168
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
174-211 |
1.57e-04 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 39.43 E-value: 1.57e-04
10 20 30
....*....|....*....|....*....|....*...
gi 1112991871 174 IELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDE 211
Cdd:cd18140 19 VKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITE 56
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
5-56 |
1.76e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.76e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1112991871 5 LAL--RMRPKTIDQVIGQEHLVGPgkiIRRMVEANRLSSMILY-GPPGIGKTSIA 56
Cdd:PRK07764 3 LALyrRYRPATFAEVIGQEHVTEP---LSTALDSGRINHAYLFsGPRGCGKTSSA 54
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
5-212 |
1.87e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 43.34 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVGpgkIIRRMVEANRLS-SMILYGPPGIGKTSIASAIAgttkyafRTFNAT--VDSKKRLQ 81
Cdd:PRK14955 6 IARKYRPKKFADITAQEHITR---TIQNSLRMGRVGhGYIFSGLRGVGKTTAARVFA-------KAVNCQrmIDDADYLQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 82 EISEEA-------KFSGGL-----------------------------------VLLLDEIHRLDKTKQDFLLPLLES-- 117
Cdd:PRK14955 76 EVTEPCgecescrDFDAGTslnisefdaasnnsvddirllrenvrygpqkgryrVYIIDEVHMLSIAAFNAFLKTLEEpp 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 118 GLVIMIGATTEnpFFSVTPAIRSRVQIFELEPLSNQDVKEALQiALSNPERgfdfpIELDEDALDFIATSTNGDLRSAFN 197
Cdd:PRK14955 156 PHAIFIFATTE--LHKIPATIASRCQRFNFKRIPLEEIQQQLQ-GICEAEG-----ISVDADALQLIGRKAQGSMRDAQS 227
|
250
....*....|....*
gi 1112991871 198 SLDLAVLSTPENDEG 212
Cdd:PRK14955 228 ILDQVIAFSVESEGE 242
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
31-223 |
2.36e-04 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 43.29 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 31 RRMVEANRLSSMILYGPPGIGKTSIASAIA----GTTKYAFRTFNATVDSKKRLQEISE-EAKFSG------GLVLLLDE 99
Cdd:TIGR03922 304 RGLPVAQTSNHMLFAGPPGTGKTTIARVVAkiycGLGVLRKPLVREVSRADLIGQYIGEsEAKTNEiidsalGGVLFLDE 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 100 IHRL----DKTKQDFLLPLLESGLVIM---------IGATTEN---PFFSVTPAIRSRV-QIFELEPLSNQDVKE-ALQI 161
Cdd:TIGR03922 384 AYTLvetgYGQKDPFGLEAIDTLLARMendrdrlvvIGAGYRKdldKFLEVNEGLRSRFtRVIEFPSYSPDELVEiARRM 463
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1112991871 162 ALSNPERgfdfpieLDEDALDfiatstngDLRSAFNSLDLAvlSTPENDEGIRHiTLDIMEN 223
Cdd:TIGR03922 464 ATERDSV-------LDDAAAD--------ALLEAATTLAQD--TTPDANGDLRR-GLDIAGN 507
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
41-141 |
2.46e-04 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 40.74 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 41 SMILYGPPGIGKTSIASAIA---------------GTT----KYAFRTfnATVDSKKRLQEISEEAKfsGGLVLLLDEIH 101
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAaalsnrpvfyvqltrDTTeedlFGRRNI--DPGGASWVDGPLVRAAR--EGEIAVLDEIN 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1112991871 102 RLDKTKQDFLLPLLESG----------------LVIMIGATTENPF--FSVTPAIRSR 141
Cdd:pfam07728 77 RANPDVLNSLLSLLDERrlllpdggelvkaapdGFRLIATMNPLDRglNELSPALRSR 134
|
|
| hflB |
PRK10733 |
ATP-dependent zinc metalloprotease FtsH; |
42-100 |
2.54e-04 |
|
ATP-dependent zinc metalloprotease FtsH;
Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 43.48 E-value: 2.54e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNAT--VD-----SKKRLQEISEEAKFSGGLVLLLDEI 100
Cdd:PRK10733 188 VLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSdfVEmfvgvGASRVRDMFEQAKKAAPCIIFIDEI 253
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
5-203 |
3.17e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.94 E-value: 3.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA---------GTTKYA-------- 66
Cdd:PRK12323 6 LARKWRPRDFTTLVGQEHVV---RALTHALEQQRLHHAYLFtGTRGVGKTTLSRILAkslnctgadGEGGITaqpcgqcr 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 67 ---------FRTF-------NATVDSKKRLQEISEEAKFSGGL-VLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATT 127
Cdd:PRK12323 83 acteidagrFVDYiemdaasNRGVDEMAQLLDKAVYAPTAGRFkVYMIDEVHMLTNHAFNAMLKTLEEppEHVKFILATT 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1112991871 128 ENPFFSVTpaIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPieldedALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK12323 163 DPQKIPVT--VLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVN------ALRLLAQAAQGSMRDALSLTDQAI 230
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
5-203 |
3.69e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 42.80 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 5 LALRMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILY-GPPGIGKTSIASAIA-------GTTKYAFRT------- 69
Cdd:PRK14958 6 LARKWRPRCFQEVIGQAPVV---RALSNALDQQYLHHAYLFtGTRGVGKTTISRILAkclncekGVSANPCNDcencrei 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 70 --------FNATVDSKKRLQEISE----------EAKFSgglVLLLDEIHRLDKTKQDFLLPLLES--GLVIMIGATTEN 129
Cdd:PRK14958 83 degrfpdlFEVDAASRTKVEDTRElldnipyaptKGRFK---VYLIDEVHMLSGHSFNALLKTLEEppSHVKFILATTDH 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1112991871 130 PFFSVTpaIRSRVQIFELEPLSnqdvkeALQIALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAV 203
Cdd:PRK14958 160 HKLPVT--VLSRCLQFHLAQLP------PLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSI 225
|
|
| RecA-like_VCP_r2 |
cd19529 |
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ... |
42-103 |
3.84e-04 |
|
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410937 [Multi-domain] Cd Length: 159 Bit Score: 40.94 E-value: 3.84e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAF------RTFNATV-DSKKRLQEISEEAKFSGGLVLLLDEIHRL 103
Cdd:cd19529 30 ILLYGPPGTGKTLLAKAVATESNANFisvkgpELLSKWVgESEKAIREIFRKARQVAPCVIFFDEIDSI 98
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
8-52 |
4.02e-04 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 42.90 E-value: 4.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1112991871 8 RMRPKTIDQVIGQEHLVgpgKIIRRMVEANRLSSMILYGPPGIGK 52
Cdd:PRK04132 12 KYRPQRLDDIVGQEHIV---KRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| RecA-like_VPS4-like |
cd19509 |
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ... |
40-126 |
5.25e-04 |
|
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410917 [Multi-domain] Cd Length: 163 Bit Score: 40.41 E-value: 5.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 40 SSMILYGPPGIGKTSIASAIAGTTKYAFRTFNAT-------VDSKKRLQEISEEAKFSGGLVLLLDEIHRL--------- 103
Cdd:cd19509 33 RGILLYGPPGTGKTLLARAVASESGSTFFSISASslvskwvGESEKIVRALFALARELQPSIIFIDEIDSLlsergsgeh 112
|
90 100 110
....*....|....*....|....*....|.
gi 1112991871 104 ---DKTKQDFL-----LPLLESGLVIMIGAT 126
Cdd:cd19509 113 easRRVKTEFLvqmdgVLNKPEDRVLVLGAT 143
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
42-107 |
5.43e-04 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 40.57 E-value: 5.43e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAFRTFNATV-------DSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTK 107
Cdd:cd19528 30 VLFYGPPGCGKTLLAKAIANECQANFISVKGPElltmwfgESEANVRDIFDKARAAAPCVLFFDELDSIAKAR 102
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
42-100 |
6.45e-04 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 42.20 E-value: 6.45e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAF------RTFNATV-DSKKRLQEISEEAKFSGGLVLLLDEI 100
Cdd:TIGR01243 490 VLLFGPPGTGKTLLAKAVATESGANFiavrgpEILSKWVgESEKAIREIFRKARQAAPAIIFFDEI 555
|
|
| RecA-like_KTNA1 |
cd19522 |
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ... |
42-143 |
7.60e-04 |
|
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410930 [Multi-domain] Cd Length: 170 Bit Score: 39.97 E-value: 7.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIA---GTTkyAFRTFNATVDSKKR------LQEISEEAKFSGGLVLLLDEIHRL--------- 103
Cdd:cd19522 36 VLMVGPPGTGKTLLAKAVAtecGTT--FFNVSSSTLTSKYRgeseklVRLLFEMARFYAPTTIFIDEIDSIcsrrgtsee 113
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1112991871 104 ----DKTKQDFLLPL---------LESGLVIMIGATTENPfFSVTPAIRSRVQ 143
Cdd:cd19522 114 heasRRVKSELLVQMdgvggasenDDPSKMVMVLAATNFP-WDIDEALRRRLE 165
|
|
| RecA-like_Yta7-like |
cd19517 |
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ... |
43-139 |
9.55e-04 |
|
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410925 [Multi-domain] Cd Length: 170 Bit Score: 39.80 E-value: 9.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 43 ILYGPPGIGKTSIASAIA-----GTTKYAFRTFNAT-------VDSKKRLQEISEEAKFSGGLVLLLDEIHRL---DKTK 107
Cdd:cd19517 38 LFHGPPGTGKTLMARALAaecskGGQKVSFFMRKGAdclskwvGEAERQLRLLFEEAYRMQPSIIFFDEIDGLapvRSSK 117
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1112991871 108 QD--------FLLPLLES----GLVIMIGATteNPFFSVTPAIR 139
Cdd:cd19517 118 QEqihasivsTLLALMDGldnrGQVVVIGAT--NRPDALDPALR 159
|
|
| PRK08903 |
PRK08903 |
DnaA regulatory inactivator Hda; Validated |
44-194 |
1.37e-03 |
|
DnaA regulatory inactivator Hda; Validated
Pssm-ID: 236347 [Multi-domain] Cd Length: 227 Bit Score: 39.96 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 44 LYGPPGIGKTSIASAIAGTTKYAFRTFnATVDSKKRLQEISEEakfSGGLVLLLDEIHRLDKTKQDFLLPLL----ESGL 119
Cdd:PRK08903 47 LWGEAGSGRSHLLQALVADASYGGRNA-RYLDAASPLLAFDFD---PEAELYAVDDVERLDDAQQIALFNLFnrvrAHGQ 122
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 120 VIMIGATTENPF-FSVTPAIRSRVQ---IFELEPLSNQDVKEALQIALSnpERGfdfpIELDEDALDFIATSTNGDLRS 194
Cdd:PRK08903 123 GALLVAGPAAPLaLPLREDLRTRLGwglVYELKPLSDADKIAALKAAAA--ERG----LQLADEVPDYLLTHFRRDMPS 195
|
|
| RecA-like_VPS4 |
cd19521 |
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ... |
40-141 |
2.28e-03 |
|
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410929 [Multi-domain] Cd Length: 170 Bit Score: 38.69 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 40 SSMILYGPPGIGKTSIASAIAGTTKYAFRTFNAT-------VDSKKRLQEISEEAKFSGGLVLLLDEIHRL--------- 103
Cdd:cd19521 41 SGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSdlvskwmGESEKLVKQLFAMARENKPSIIFIDEVDSLcgtrgeges 120
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1112991871 104 ---DKTKQDFLLPLLESGL----VIMIGATteNPFFSVTPAIRSR 141
Cdd:cd19521 121 easRRIKTELLVQMNGVGNdsqgVLVLGAT--NIPWQLDSAIRRR 163
|
|
| TIP49 |
pfam06068 |
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ... |
15-60 |
2.61e-03 |
|
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.
Pssm-ID: 399217 [Multi-domain] Cd Length: 347 Bit Score: 39.60 E-value: 2.61e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1112991871 15 DQVIGQEHLVGPGKIIRRMVEANRLS--SMILYGPPGIGKTSIASAIA 60
Cdd:pfam06068 24 GGLVGQEKAREAAGVIVEMIKEGKIAgrAVLIAGPPGTGKTALAIAIS 71
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
42-103 |
2.64e-03 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 38.24 E-value: 2.64e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 42 MILYGPPGIGKTSIASAIAGTTKYAF------RTFNATV-DSKKRLQEISEEAKFSGGLVLLLDEIHRL 103
Cdd:cd19530 33 VLLYGPPGCGKTLLAKAVANESGANFisvkgpELLNKYVgESERAVRQVFQRARASAPCVIFFDEVDAL 101
|
|
| RecA-like_PEX6_r2 |
cd19527 |
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ... |
38-103 |
3.12e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410935 [Multi-domain] Cd Length: 160 Bit Score: 38.26 E-value: 3.12e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1112991871 38 RLSSMILYGPPGIGKTSIASAIAGTTKYAFRT------FNATV-DSKKRLQEISEEAKFSGGLVLLLDEIHRL 103
Cdd:cd19527 25 KRSGILLYGPPGTGKTLLAKAIATECSLNFLSvkgpelINMYIgESEANVREVFQKARDAKPCVIFFDELDSL 97
|
|
| RecA-like_BCS1 |
cd19510 |
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ... |
43-80 |
3.32e-03 |
|
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410918 [Multi-domain] Cd Length: 153 Bit Score: 38.10 E-value: 3.32e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1112991871 43 ILYGPPGIGKTSIASAIAGTTKYAFRTFNAT--VDSKKRL 80
Cdd:cd19510 27 LLYGPPGTGKSSFIAALAGELDYDICDLNLSevVLTDDRL 66
|
|
| PRK08084 |
PRK08084 |
DnaA inactivator Hda; |
136-200 |
4.29e-03 |
|
DnaA inactivator Hda;
Pssm-ID: 181224 [Multi-domain] Cd Length: 235 Bit Score: 38.51 E-value: 4.29e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1112991871 136 PAIRSRV---QIFELEPLSNQDVKEALQiaLSNPERGFdfpiELDEDALDFIATSTNGDLRSAFNSLD 200
Cdd:PRK08084 150 PDLASRLdwgQIYKLQPLSDEEKLQALQ--LRARLRGF----ELPEDVGRFLLKRLDREMRTLFMTLD 211
|
|
| RecA-like_PEX1_r2 |
cd19526 |
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ... |
38-67 |
4.76e-03 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410934 [Multi-domain] Cd Length: 158 Bit Score: 37.41 E-value: 4.76e-03
10 20 30
....*....|....*....|....*....|.
gi 1112991871 38 RLSSMIL-YGPPGIGKTSIASAIAGTTKYAF 67
Cdd:cd19526 25 RLRSGILlYGPPGCGKTLLASAIASECGLNF 55
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
43-100 |
5.81e-03 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 37.60 E-value: 5.81e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1112991871 43 ILYGPPGIGKTSIASAIAGTTKYAFRTFNAT--VD-----SKKRLQEISEEAKFSGGLVLLLDEI 100
Cdd:cd19501 41 LLVGPPGTGKTLLAKAVAGEAGVPFFSISGSdfVEmfvgvGASRVRDLFEQAKKNAPCIVFIDEI 105
|
|
| PspF |
COG1221 |
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ... |
42-130 |
6.38e-03 |
|
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];
Pssm-ID: 440834 [Multi-domain] Cd Length: 835 Bit Score: 38.94 E-value: 6.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1112991871 42 MILYGPPGIGKTSIASAIagtTKYA-----------FRTFN-------------------------ATVDsKKRLqeIsE 85
Cdd:COG1221 133 TLILGPTGVGKSFFAELM---YEYAieigvlpedapFVVFNcadyannpqllmsqlfgyvkgaftgADKD-KEGL--I-E 205
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1112991871 86 EAKfsGGlVLLLDEIHRLDKTKQDFLLPLLESGL--------------VIMIGATTENP 130
Cdd:COG1221 206 KAD--GG-ILFLDEVHRLPPEGQEMLFTFMDKGIyrrlgetektrkanVRIIFATTEDP 261
|
|
| RecA-like_Lon |
cd19500 |
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ... |
42-60 |
9.17e-03 |
|
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410908 [Multi-domain] Cd Length: 182 Bit Score: 37.15 E-value: 9.17e-03
|
| |
