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Conserved domains on  [gi|1109663863|ref|NP_001334581|]
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B-cell CLL/lymphoma 7 protein family member C isoform 1 [Mus musculus]

Protein Classification

BCL_N domain-containing protein( domain architecture ID 10520246)

BCL_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BCL_N pfam04714
BCL7, N-terminal conserver region; Members of the BCL family have significant sequence ...
 4-50 1.83e-26

BCL7, N-terminal conserver region; Members of the BCL family have significant sequence similarity at their N-terminus, represented in this family. The function of BCL7 proteins is unknown. They may be involved in early development. In addition, BCL7B is commonly hemizygously deleted in patients with Williams syndrome.


:

Pssm-ID: 461406  Cd Length: 48  Bit Score: 96.78  E-value: 1.83e-26
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1109663863   4 RTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVP 50
Cdd:pfam04714   2 RSLRAETRSRAKDDVKRVILSIEKVRKWEKKWVTIGDTSMRIYKWVP 48
Herpes_pp85 super family cl27999
Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25); This family includes UL25 proteins from ...
 93-181 6.30e-03

Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25); This family includes UL25 proteins from HCMV, as well as U14 proteins from HHV 6 and HHV7. These 85 kD phosphoproteins appear to act as structural antigens, but their precise function is otherwise unknown.


The actual alignment was detected with superfamily member PHA03249:

Pssm-ID: 355693  Cd Length: 653  Bit Score: 37.68  E-value: 6.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1109663863  93 NDENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPE-VITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPE 171
Cdd:PHA03249   56 SDNKSSFEVVSETDSGSEAEAERGRRAGMGGRNKATKPSRrNKTTQCRPTSLALATAATMPATPSSGKSPKVSSPPSIPS 135

                          90
                  ....*....|
gi 1109663863 172 LLEAEDSGVR 181
Cdd:PHA03249  136 LSEEDEGAER 145
 
Name Accession Description Interval E-value
BCL_N pfam04714
BCL7, N-terminal conserver region; Members of the BCL family have significant sequence ...
 4-50 1.83e-26

BCL7, N-terminal conserver region; Members of the BCL family have significant sequence similarity at their N-terminus, represented in this family. The function of BCL7 proteins is unknown. They may be involved in early development. In addition, BCL7B is commonly hemizygously deleted in patients with Williams syndrome.


Pssm-ID: 461406  Cd Length: 48  Bit Score: 96.78  E-value: 1.83e-26
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1109663863   4 RTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVP 50
Cdd:pfam04714   2 RSLRAETRSRAKDDVKRVILSIEKVRKWEKKWVTIGDTSMRIYKWVP 48
PHA03249 PHA03249
DNA packaging tegument protein UL25; Provisional
 93-181 6.30e-03

DNA packaging tegument protein UL25; Provisional


Pssm-ID: 223023  Cd Length: 653  Bit Score: 37.68  E-value: 6.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1109663863  93 NDENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPE-VITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPE 171
Cdd:PHA03249   56 SDNKSSFEVVSETDSGSEAEAERGRRAGMGGRNKATKPSRrNKTTQCRPTSLALATAATMPATPSSGKSPKVSSPPSIPS 135

                          90
                  ....*....|
gi 1109663863 172 LLEAEDSGVR 181
Cdd:PHA03249  136 LSEEDEGAER 145
 
Name Accession Description Interval E-value
BCL_N pfam04714
BCL7, N-terminal conserver region; Members of the BCL family have significant sequence ...
 4-50 1.83e-26

BCL7, N-terminal conserver region; Members of the BCL family have significant sequence similarity at their N-terminus, represented in this family. The function of BCL7 proteins is unknown. They may be involved in early development. In addition, BCL7B is commonly hemizygously deleted in patients with Williams syndrome.


Pssm-ID: 461406  Cd Length: 48  Bit Score: 96.78  E-value: 1.83e-26
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1109663863   4 RTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVP 50
Cdd:pfam04714   2 RSLRAETRSRAKDDVKRVILSIEKVRKWEKKWVTIGDTSMRIYKWVP 48
PHA03249 PHA03249
DNA packaging tegument protein UL25; Provisional
 93-181 6.30e-03

DNA packaging tegument protein UL25; Provisional


Pssm-ID: 223023  Cd Length: 653  Bit Score: 37.68  E-value: 6.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1109663863  93 NDENSNQSFHSEGSLQKGAEPSPGGTPQPSRPGSPTGPPE-VITEDTQPPQLGQERDPGGTPAGGTDEPPKLTKEEPVPE 171
Cdd:PHA03249   56 SDNKSSFEVVSETDSGSEAEAERGRRAGMGGRNKATKPSRrNKTTQCRPTSLALATAATMPATPSSGKSPKVSSPPSIPS 135

                          90
                  ....*....|
gi 1109663863 172 LLEAEDSGVR 181
Cdd:PHA03249  136 LSEEDEGAER 145
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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