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Conserved domains on  [gi|1104461168|gb|APD30571|]
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Replication-enhancer protein [Tomato mottle leaf curl virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gemini_AL3 super family cl03201
Geminivirus AL3 protein; Geminiviruses are small, ssDNA-containing plant viruses. ...
 2-121 5.62e-49

Geminivirus AL3 protein; Geminiviruses are small, ssDNA-containing plant viruses. Geminiviruses contain three ORFs (designated AL1, AL2, and AL3) that overlap and are specified by multiple polycistronic mRNAs. The AL3 protein comprises approximately 0.05% of the cellular proteins and is present in the soluble and organelle fractions. AL3 may form oligomers. Immunoprecipitation of AL3 in a baculovirus expression system extracts expressing both AL1 pfam00799 and AL3 showed that the two proteins also complex with each other. The AL3 protein is involved in viral replication.


The actual alignment was detected with superfamily member pfam01407:

Pssm-ID: 279715  Cd Length: 119  Bit Score: 152.74  E-value: 5.62e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1104461168   2 DSRTGELITAHQAQNGAFIWEVQNPLYFKITNVENPiHTNTRIYHIQIRFNHNLRRALDLHKCFLNFQIWTTSTTASGTT 81
Cdd:pfam01407   1 DSRTGELITYHQAQNSVYFDDVPNPLYFKLQNTETM-ATGNKIYTIQIRFNHNLRKALGLHKCWLNLVVLSVSPRLSGEA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1104461168  82 YLNRFSDLVNMYLDRLGVISINNVIRAVQFATDKPYVNYV 121
Cdd:pfam01407  80 LLDRFKFHVMKYLNNLGVISINNVIRSINHVLYEEFIDLF 119
 
Name Accession Description Interval E-value
Gemini_AL3 pfam01407
Geminivirus AL3 protein; Geminiviruses are small, ssDNA-containing plant viruses. ...
 2-121 5.62e-49

Geminivirus AL3 protein; Geminiviruses are small, ssDNA-containing plant viruses. Geminiviruses contain three ORFs (designated AL1, AL2, and AL3) that overlap and are specified by multiple polycistronic mRNAs. The AL3 protein comprises approximately 0.05% of the cellular proteins and is present in the soluble and organelle fractions. AL3 may form oligomers. Immunoprecipitation of AL3 in a baculovirus expression system extracts expressing both AL1 pfam00799 and AL3 showed that the two proteins also complex with each other. The AL3 protein is involved in viral replication.


Pssm-ID: 279715  Cd Length: 119  Bit Score: 152.74  E-value: 5.62e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1104461168   2 DSRTGELITAHQAQNGAFIWEVQNPLYFKITNVENPiHTNTRIYHIQIRFNHNLRRALDLHKCFLNFQIWTTSTTASGTT 81
Cdd:pfam01407   1 DSRTGELITYHQAQNSVYFDDVPNPLYFKLQNTETM-ATGNKIYTIQIRFNHNLRKALGLHKCWLNLVVLSVSPRLSGEA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1104461168  82 YLNRFSDLVNMYLDRLGVISINNVIRAVQFATDKPYVNYV 121
Cdd:pfam01407  80 LLDRFKFHVMKYLNNLGVISINNVIRSINHVLYEEFIDLF 119
 
Name Accession Description Interval E-value
Gemini_AL3 pfam01407
Geminivirus AL3 protein; Geminiviruses are small, ssDNA-containing plant viruses. ...
 2-121 5.62e-49

Geminivirus AL3 protein; Geminiviruses are small, ssDNA-containing plant viruses. Geminiviruses contain three ORFs (designated AL1, AL2, and AL3) that overlap and are specified by multiple polycistronic mRNAs. The AL3 protein comprises approximately 0.05% of the cellular proteins and is present in the soluble and organelle fractions. AL3 may form oligomers. Immunoprecipitation of AL3 in a baculovirus expression system extracts expressing both AL1 pfam00799 and AL3 showed that the two proteins also complex with each other. The AL3 protein is involved in viral replication.


Pssm-ID: 279715  Cd Length: 119  Bit Score: 152.74  E-value: 5.62e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1104461168   2 DSRTGELITAHQAQNGAFIWEVQNPLYFKITNVENPiHTNTRIYHIQIRFNHNLRRALDLHKCFLNFQIWTTSTTASGTT 81
Cdd:pfam01407   1 DSRTGELITYHQAQNSVYFDDVPNPLYFKLQNTETM-ATGNKIYTIQIRFNHNLRKALGLHKCWLNLVVLSVSPRLSGEA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1104461168  82 YLNRFSDLVNMYLDRLGVISINNVIRAVQFATDKPYVNYV 121
Cdd:pfam01407  80 LLDRFKFHVMKYLNNLGVISINNVIRSINHVLYEEFIDLF 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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