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Conserved domains on  [gi|1103528792|gb|APD14951|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Trigonidium sjostedti]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 6.91e-21

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.04  E-value: 6.91e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  4 LLIIYFIFLIYFSGLWMFSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNIVR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1103528792 84 SFGNNYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 6.91e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.04  E-value: 6.91e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  4 LLIIYFIFLIYFSGLWMFSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNIVR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1103528792 84 SFGNNYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 1.42e-05

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 39.85  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  5 LIIYFIFLIYFSGLWMFSSkRKYLLISLLSLEYMMLSVFLMLVF--YLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNIV 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLfgRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1103528792 83 RSFGNNYFQSFSILQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 4-92 6.91e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 79.04  E-value: 6.91e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  4 LLIIYFIFLIYFSGLWMFSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNIVR 83
Cdd:MTH00162   1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                 ....*....
gi 1103528792 84 SFGNNYFQS 92
Cdd:MTH00162  81 SHGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 6-98 3.19e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 57.16  E-value: 3.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  6 IIYFIFLIYFSGLWMFSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNIVRSF 85
Cdd:MTH00149   5 LLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLH 84

                         90
                 ....*....|...
gi 1103528792 86 GNNYFQSFSILQC 98
Cdd:MTH00149  85 GNDYVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 2-98 2.00e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 54.98  E-value: 2.00e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  2 MKLLIIYFIFLIYFSGLWMFSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNI 81
Cdd:MTH00188   1 MFFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSL 80

                         90
                 ....*....|....*..
gi 1103528792 82 VRSFGNNYFQSFSILQC 98
Cdd:MTH00188  81 IRSHGSDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.24e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 49.46  E-value: 3.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  1 MMKLLIIYFIFLIYFSGLwmfSSKRKYLLISLLSLEYMMLSVFLMLVFYL--TMMMFQMYFLLIFLVFVVCEGALGLSVL 78
Cdd:MTH00125   2 TPTHFSLYTAFMLSLLGL---SFHRTHLMSALLCLESMMLSLFIMLSLWPitTQTPSFTPMPIILLTFSACEAGTGLALL 78

                         90       100
                 ....*....|....*....|
gi 1103528792 79 VNIVRSFGNNYFQSFSILQC 98
Cdd:MTH00125  79 VATTRTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 25-98 1.02e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 45.73  E-value: 1.02e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1103528792 25 RKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFL--LIFLVFVVCEGALGLSVLVNIVRSFGNNYFQSFSILQC 98
Cdd:MTH00126  23 RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 11-98 1.37e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 45.31  E-value: 1.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792 11 FLIYFSGLWMFsskRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFL--LIFLVFVVCEGALGLSVLVNIVRSFGNN 88
Cdd:MTH00107  12 FTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMmpIILLVFAACEAAVGLALLVMVSNTYGTD 88

                         90
                 ....*....|
gi 1103528792 89 YFQSFSILQC 98
Cdd:MTH00107  89 YVQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.72e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 44.98  E-value: 1.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  1 MMKLLIIYFIFLIYFSGLwmfSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMMMFQMYFLL--IFLVFVVCEGALGLSVL 78
Cdd:MTH00067   2 SPTYFTFYSAFLLGLMGL---AFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLpmFMLTFSACEASTGLALM 78

                         90       100
                 ....*....|....*....|
gi 1103528792 79 VNIVRSFGNNYFQSFSILQC 98
Cdd:MTH00067  79 VATTRTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 1.42e-05

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 39.85  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  5 LIIYFIFLIYFSGLWMFSSkRKYLLISLLSLEYMMLSVFLMLVF--YLTMMMFQMYFLLIFLVFVVCEGALGLSVLVNIV 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLfgRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 1103528792 83 RSFGNNYFQSFSILQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 6-98 2.04e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 39.73  E-value: 2.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  6 IIYFIFLIYFSGLWMFSSKRKYLLISLLSLEYMMLSVFLMLVFYLTMM-MFQMYFLLIFLVFVVCEGALGLSVLVNIVRS 84
Cdd:MTH00013   4 PLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFAnQVNGMLAIVLLTFGACEASLGLSLLVLMTRS 83

                         90
                 ....*....|....
gi 1103528792 85 FGNNYFQSFSILQC 98
Cdd:MTH00013  84 YGNDMLKSLTSNKC 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 1-96 2.19e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 39.54  E-value: 2.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1103528792  1 MMKLLIIYFIFLIYfsglwMFSSKRKYLLISLLSLEYMMLSVF--LMLVFYLTMMMFQMYFLLIFLVFVVCEGALGLSVL 78
Cdd:MTH00181   1 MMFVFISAFILLLL-----GLSLYKTHLLSLLLCLEGMMLFLFllLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLL 75

                         90
                 ....*....|....*...
gi 1103528792 79 VNIVRSFGNNYFQSFSIL 96
Cdd:MTH00181  76 VATNRTHGSDHLLKFNLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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