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Conserved domains on  [gi|1101180460|gb|OIP32705|]
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hypothetical protein AUK23_03805 [Deltaproteobacteria bacterium CG2_30_43_15]

Protein Classification

thiolase family protein( domain architecture ID 10093593)

thiolase family protein similar to Sulfurisphaera tokodaii acetyl-CoA C-acetyltransferase, which catalyzes the transfer of an acetyl group from acetyl-CoA to another molecule of acetyl-CoA to form acetoacetyl-CoA

CATH:  3.40.47.10
EC:  2.3.1.-
Gene Ontology:  GO:0016746
PubMed:  16356722

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SCP-x_thiolase cd00829
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ...
 12-388 1.88e-154

Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.


:

Pssm-ID: 238425 [Multi-domain]  Cd Length: 375  Bit Score: 440.55  E-value: 1.88e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  12 VGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCipgTGFRREIVTGAGLAEPIRFFPRPVSRMEN 91
Cdd:cd00829     1 VGVGMTPFGRRSDRSPLELAAEAARAALD--DAGLEPADIDAVVVGNA---AGGRFQSFPGALIAEYLGLLGKPATRVEA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  92 ACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTG-VAYHSWWHPRGASAPQRFGSLATAHMDKFGTKR 170
Cdd:cd00829    76 AGASGSAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEAGGRASdLEWEGPEPPGGLTPPALYALAARRYMHRYGTTR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 171 DHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTGLA 250
Cdd:cd00829   156 EDLAKVAVKNHRNAARNPYAQFRKPITVEDVLNSRMIADPLRLLDCCPVSDGAAAVVLASEERARELTDRPVWILGVGAA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 251 TDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKP 330
Cdd:cd00829   236 SDTPSLSERDDFLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFCEKGEGGKLVREGDTAIGGDLP 315

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 331 CNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGLGTVVLV 388
Cdd:cd00829   316 VNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARQVPGARVGLAHNIGGTGSAAVV 373
 
Name Accession Description Interval E-value
SCP-x_thiolase cd00829
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ...
 12-388 1.88e-154

Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.


Pssm-ID: 238425 [Multi-domain]  Cd Length: 375  Bit Score: 440.55  E-value: 1.88e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  12 VGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCipgTGFRREIVTGAGLAEPIRFFPRPVSRMEN 91
Cdd:cd00829     1 VGVGMTPFGRRSDRSPLELAAEAARAALD--DAGLEPADIDAVVVGNA---AGGRFQSFPGALIAEYLGLLGKPATRVEA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  92 ACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTG-VAYHSWWHPRGASAPQRFGSLATAHMDKFGTKR 170
Cdd:cd00829    76 AGASGSAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEAGGRASdLEWEGPEPPGGLTPPALYALAARRYMHRYGTTR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 171 DHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTGLA 250
Cdd:cd00829   156 EDLAKVAVKNHRNAARNPYAQFRKPITVEDVLNSRMIADPLRLLDCCPVSDGAAAVVLASEERARELTDRPVWILGVGAA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 251 TDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKP 330
Cdd:cd00829   236 SDTPSLSERDDFLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFCEKGEGGKLVREGDTAIGGDLP 315

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 331 CNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGLGTVVLV 388
Cdd:cd00829   316 VNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARQVPGARVGLAHNIGGTGSAAVV 373
PRK06064 PRK06064
thiolase domain-containing protein;
9-394 2.59e-153

thiolase domain-containing protein;


Pssm-ID: 235688 [Multi-domain]  Cd Length: 389  Bit Score: 438.18  E-value: 2.59e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCIPGTgFRREIVTGAGLAEPIRFFPRPVSR 88
Cdd:PRK06064    4 VAIIGVGQTKFGELWDVSLRDLAVEAGLEALE--DAGIDGKDIDAMYVGNMSAGL-FVSQEHIAALIADYAGLAPIPATR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  89 MENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHSWWHPRGASAPQRFGSLATAHMDKFGT 168
Cdd:PRK06064   81 VEAACASGGAALRQAYLAVASGEADVVLAAGVEKMTDVPTPDATEAIARAGDYEWEEFFGATFPGLYALIARRYMHKYGT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 169 KRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTG 248
Cdd:PRK06064  161 TEEDLALVAVKNHYNGSKNPYAQFQKEITVEQVLNSPPVADPLKLLDCSPITDGAAAVILASEEKAKEYTDTPVWIKASG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 249 LATDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGT 328
Cdd:PRK06064  241 QASDTIALHDRKDFTTLDAAVVAAEKAYKMAGIEPKDIDVAEVHDCFTIAEILAYEDLGFAKKGEGGKLAREGQTYIGGD 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 329 KPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEA--GERQVKDAQIGCTHNLGGLGTVVLVNIFGKE 394
Cdd:PRK06064  321 IPVNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAekGRQQVIGAGYGLTHNVGGTGHTAVVHILSRK 388
Thiolase_N pfam00108
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ...
 9-232 5.54e-17

Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.


Pssm-ID: 459676 [Multi-domain]  Cd Length: 260  Bit Score: 80.04  E-value: 5.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGE----LFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCI-PGTGFR--REIVTGAGLAEPIrf 81
Cdd:pfam00108   1 VVIVSAARTPFGSfggsLKDVSAVELGAEAIKAALE--RAGVDPEDVDEVIVGNVLqAGEGQNpaRQAALKAGIPDSA-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  82 fprPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHS--------WWHPRGASAPQ 153
Cdd:pfam00108  77 ---PAVTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDARSGLKHGDekkhdlliPDGLTDAFNGY 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 154 RFGSLATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYT-HFNFEI--------------TVEQALNAPIISWPLGLF---- 214
Cdd:pfam00108 154 HMGLTAENVAKKYGISREEQDAFAVKSHQKAAAAPKAgKFKDEIvpvtvkgrkgkptvDKDEGIRPPTTAEPLAKLkpaf 233

                         250       260
                  ....*....|....*....|....*..
gi 1101180460 215 ---------DSCPTTDGAAAILLARQD 232
Cdd:pfam00108 234 dkegtvtagNASPINDGAAAVLLMSES 260
PaaJ COG0183
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ...
 28-348 1.23e-14

Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 439953 [Multi-domain]  Cd Length: 391  Bit Score: 74.72  E-value: 1.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  28 EDMIVGAYRACLKSVdkGIDEKDIEAAWLGTCIP-GTGFR--REIVTGAGLAEPIrffprP---VSRMenaCCTGSDAVR 101
Cdd:COG0183    27 DDLGAAVIKALLERA--GLDPEAVDDVILGCVLQaGQGQNpaRQAALLAGLPESV-----PavtVNRV---CGSGLQAVA 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 102 NAAFAVAAGVYDLVLVVGAEKMRDIP----SRDSLIAQTGVAYHSWWHPRGASAPQRFGSLATAHM--DKFGTKRDHLAM 175
Cdd:COG0183    97 LAAQAIAAGDADVVIAGGVESMSRAPmllpKARWGYRMNAKLVDPMINPGLTDPYTGLSMGETAENvaERYGISREEQDA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 176 IAVKNHH-------NGTLD----PYT--------------HFNFEITVEQ--ALNAPiiswplglFD---------SCPT 219
Cdd:COG0183   177 FALRSHQraaaaiaAGRFDdeivPVEvpdrkgevvvdrdeGPRPDTTLEKlaKLKPA--------FKkdgtvtagnASGI 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 220 TDGAAAILLARQDRAKEYTDQPL-YFLGTGLA-TDPLFLPWkknfiefpATQEAAKVAYEMAGIGPDDIDLAELHDCFTI 297
Cdd:COG0183   249 NDGAAALLLMSEEAAKELGLKPLaRIVAYAVAgVDPEIMGI--------GPVPATRKALARAGLTLDDIDLIEINEAFAA 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1101180460 298 TELLTYEDMGfckkgeggkwieeghptLNGTKpCNPSGGLKAKGHPIGATG 348
Cdd:COG0183   321 QVLAVLRELG-----------------LDPDK-VNVNGGAIALGHPLGASG 353
 
Name Accession Description Interval E-value
SCP-x_thiolase cd00829
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ...
 12-388 1.88e-154

Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.


Pssm-ID: 238425 [Multi-domain]  Cd Length: 375  Bit Score: 440.55  E-value: 1.88e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  12 VGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCipgTGFRREIVTGAGLAEPIRFFPRPVSRMEN 91
Cdd:cd00829     1 VGVGMTPFGRRSDRSPLELAAEAARAALD--DAGLEPADIDAVVVGNA---AGGRFQSFPGALIAEYLGLLGKPATRVEA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  92 ACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTG-VAYHSWWHPRGASAPQRFGSLATAHMDKFGTKR 170
Cdd:cd00829    76 AGASGSAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEAGGRASdLEWEGPEPPGGLTPPALYALAARRYMHRYGTTR 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 171 DHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTGLA 250
Cdd:cd00829   156 EDLAKVAVKNHRNAARNPYAQFRKPITVEDVLNSRMIADPLRLLDCCPVSDGAAAVVLASEERARELTDRPVWILGVGAA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 251 TDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKP 330
Cdd:cd00829   236 SDTPSLSERDDFLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFCEKGEGGKLVREGDTAIGGDLP 315

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 331 CNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGLGTVVLV 388
Cdd:cd00829   316 VNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARQVPGARVGLAHNIGGTGSAAVV 373
PRK06064 PRK06064
thiolase domain-containing protein;
9-394 2.59e-153

thiolase domain-containing protein;


Pssm-ID: 235688 [Multi-domain]  Cd Length: 389  Bit Score: 438.18  E-value: 2.59e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCIPGTgFRREIVTGAGLAEPIRFFPRPVSR 88
Cdd:PRK06064    4 VAIIGVGQTKFGELWDVSLRDLAVEAGLEALE--DAGIDGKDIDAMYVGNMSAGL-FVSQEHIAALIADYAGLAPIPATR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  89 MENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHSWWHPRGASAPQRFGSLATAHMDKFGT 168
Cdd:PRK06064   81 VEAACASGGAALRQAYLAVASGEADVVLAAGVEKMTDVPTPDATEAIARAGDYEWEEFFGATFPGLYALIARRYMHKYGT 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 169 KRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTG 248
Cdd:PRK06064  161 TEEDLALVAVKNHYNGSKNPYAQFQKEITVEQVLNSPPVADPLKLLDCSPITDGAAAVILASEEKAKEYTDTPVWIKASG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 249 LATDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGT 328
Cdd:PRK06064  241 QASDTIALHDRKDFTTLDAAVVAAEKAYKMAGIEPKDIDVAEVHDCFTIAEILAYEDLGFAKKGEGGKLAREGQTYIGGD 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 329 KPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEA--GERQVKDAQIGCTHNLGGLGTVVLVNIFGKE 394
Cdd:PRK06064  321 IPVNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAekGRQQVIGAGYGLTHNVGGTGHTAVVHILSRK 388
PRK06157 PRK06157
acetyl-CoA acetyltransferase; Validated
 9-394 5.96e-131

acetyl-CoA acetyltransferase; Validated


Pssm-ID: 180433 [Multi-domain]  Cd Length: 398  Bit Score: 381.68  E-value: 5.96e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCI--PGTGfrreiVTGAGLAEPIRFFPRPV 86
Cdd:PRK06157    9 VAILGMGCTKFGERWDAGAEDLMVEAFLEALA--DAGIEPKDIDAAWFGTHYdeIGSG-----KSGTPLSRALRLPNIPV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  87 SRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHSWWhpRGASAPQRFGSLATAHMDKF 166
Cdd:PRK06157   82 TRVENFCATGSEAFRGAVYAVASGAYDIALALGVEKLKDTGYGGLPVANPGTLADMTM--PNVTAPGNFAQLASAYAAKY 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 167 GTKRDHL----AMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQ-P 241
Cdd:PRK06157  160 GVSREDLkramAHVSVKSHANGARNPKAHLRKAVTEEQVLKAPMIAGPLGLFDCCGVSDGAAAAIVTTPEIARALGKKdP 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 242 LYFLGTGLATDPLfLPWKKN---FIEFPATQEAAKVAYEMAGI-GP-DDIDLAELHDCFTITELLTYEDMGFCKKGEGGK 316
Cdd:PRK06157  240 VYVKALQLAVSNG-WELQYNgwdGSYFPTTRIAARKAYREAGItDPrEELSMAEVHDCFSITELVTMEDLGLSERGQAWR 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 317 WIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGL--GTVVLVNIFGKE 394
Cdd:PRK06157  319 DVLDGFFDADGGLPCQIDGGLKCFGHPIGASGLRMLYEMYLQLLGRAGERQLKNPRLALTHNLGGApgQNVCSVSIVGRE 398
PRK12578 PRK12578
thiolase domain-containing protein;
9-393 5.40e-114

thiolase domain-containing protein;


Pssm-ID: 183606 [Multi-domain]  Cd Length: 385  Bit Score: 337.97  E-value: 5.40e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMivgAYRACLKSV-DKGIDEKDIEAAWLGTcipgTGFRR-EIVTGAGLAEPIRFFPRPV 86
Cdd:PRK12578    3 VAVIGVGNSKFGRRDDVSVQEL---AWESIKEALnDAGVSQTDIELVVVGS----TAYRGiELYPAPIVAEYSGLTGKVP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  87 SRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSL-IAQTGVAYHSWWHPRGASAPQRFGSLATAHMDK 165
Cdd:PRK12578   76 LRVEAMCATGLAASLTAYTAVASGLVDMAIAVGVDKMTEVDTSTSLaIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 166 FGTKRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEY-TDQPLYF 244
Cdd:PRK12578  156 YGTTEEQMALVSVKAHKYGAMNPKAHFQKPVTVEEVLKSRAISWPIKLLDSCPISDGSATAIFASEEKVKELkIDSPVWI 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 245 LGTGLATDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPT 324
Cdd:PRK12578  236 TGIGYANDYAYVARRGEWVGFKATQLAARQAYNMAKVTPNDIEVATVHDAFTIAEIMGYEDLGFTEKGKGGKFIEEGQSE 315

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 325 LNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVK-DAQIGCTHNLGGLGTVVLVNIFGK 393
Cdd:PRK12578  316 KGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEAGKLQQPlKKYIGLVHNVGGTGHFAYVMILRR 385
PRK08256 PRK08256
lipid-transfer protein; Provisional
 9-393 6.46e-99

lipid-transfer protein; Provisional


Pssm-ID: 181327 [Multi-domain]  Cd Length: 391  Bit Score: 299.51  E-value: 6.46e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKF---GElfDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLG------TCipgtGFR---REIVTGAgla 76
Cdd:PRK08256    3 VFVAGVGMTPFekpGA--SWDYPDMAAEAGRAALA--DAGIDYDAVQQAYVGyvygdsTS----GQRalyEVGMTGI--- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  77 epirffprPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMR---------DIPS-----RDSLIAQTGVAyhs 142
Cdd:PRK08256   72 --------PIVNVNNNCSTGSTALFLARQAVRSGAADCALALGFEQMQpgalgsvwdDRPSplerfDKALAELQGFD--- 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 143 wwhpRGASAPQRFGSLATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDG 222
Cdd:PRK08256  141 ----PAPPALRMFGGAGREHMEKYGTTAETFAKIGVKARRHAANNPYAQFRDEYTLEDVLASPMIWGPLTRLQCCPPTCG 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 223 AAAILLARQDRAKEY-TDQPLYFLGTGLATDP--LFLPWK-KNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTIT 298
Cdd:PRK08256  217 AAAAIVCSEEFARKHgLDRAVEIVAQAMTTDTpsTFDGRSmIDLVGYDMTRAAAQQVYEQAGIGPEDIDVVELHDCFSAN 296

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 299 ELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHN 378
Cdd:PRK08256  297 ELLTYEALGLCPEGEAEKFIDDGDNTYGGRWVVNPSGGLLSKGHPLGATGLAQCAELTWQLRGTAGARQVEGARLALQHN 376

                         410
                  ....*....|....*
gi 1101180460 379 LgGLGTVVLVNIFGK 393
Cdd:PRK08256  377 L-GLGGACVVTLYQR 390
PRK07516 PRK07516
thiolase domain-containing protein;
9-390 4.02e-96

thiolase domain-containing protein;


Pssm-ID: 181013 [Multi-domain]  Cd Length: 389  Bit Score: 292.24  E-value: 4.02e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMIVGAYRACLksVDKGIDEKDIEAAWLGTCipGTGFRREIVTGA--GLAEP-IRFfpRP 85
Cdd:PRK07516    4 ASIVGWAHTPFGKLDAETLESLIVRVAREAL--AHAGIAAGDVDGIFLGHF--NAGFSPQDFPASlvLQADPaLRF--KP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  86 VSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHSWWHPRGASAPQRFGSLATAHMDK 165
Cdd:PRK07516   78 ATRVENACATGSAAVYAALDAIEAGRARIVLVVGAEKMTATPTAEVGDILLGASYLKEEGDTPGGFAGVFGRIAQAYFQR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 166 FGTKRDHLAMIAVKNHHNGTLDPYTH----FNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEyTDQP 241
Cdd:PRK07516  158 YGDQSDALAMIAAKNHANGVANPYAQmrkdLGFEFCRTVSEKNPLVAGPLRRTDCSLVSDGAAALVLADAETARA-LQRA 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 242 LYFLGTGLATDplFLPW-KKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEE 320
Cdd:PRK07516  237 VRFRARAHVND--FLPLsRRDPLAFEGPRRAWQRALAQAGVTLDDLSFVETHDCFTIAELIEYEAMGLAPPGQGARAIRE 314

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 321 GHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGLGTVVLVNI 390
Cdd:PRK07516  315 GWTAKDGKLPVNPSGGLKAKGHPIGATGVSMHVLAAMQLTGEAGGMQIPGAKLAGVFNMGGAAVANYVSI 384
PRK06365 PRK06365
thiolase domain-containing protein;
3-390 8.15e-79

thiolase domain-containing protein;


Pssm-ID: 235785 [Multi-domain]  Cd Length: 430  Bit Score: 249.44  E-value: 8.15e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   3 KQKGLPVAVVGAGMIKFGELF-DQSYEDMIVGAYRACLKSVDKGIDEKDIEAAWLGTcipgTGFRREIVTGAGLAEPIRF 81
Cdd:PRK06365   12 KKKSRDVYMVAAGVTKFDKASpYMDFRERVKKAFDYAMNDAGLTLADIDGSVASYFS----DHFQRQLLAGIMVQDYLGL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  82 FPRPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRD-----SLIAQTgvayhSWWHPRGASAPQRFG 156
Cdd:PRK06365   88 VPKPSKRIEGGGATGGLAFQAGYEEIASGRMDCVAVYGFETMSHVNTWKgnefiALASDT-----NFDYPLGGFYTGYYA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 157 SLATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKE 236
Cdd:PRK06365  163 MMAVRHMYEFGTTVEQLAKVSVKNHGNAIHNPFAQSPMKITVEDVRKSPMVSYPLTRLDVCAMSDGAACAILASEDKAFE 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 237 YTDQPLYFLGTGLATDPL-----------FLPWKK----------NFIEFPATQEAAKVAYEMAGIGP--DDIDLAELHD 293
Cdd:PRK06365  243 ITDKPVLIKAIGTGSDTLrladrpfgevpLLPNESpddykdlrypGVHSFRAGRMAAKEAYEMAGITDplNDLDLIELHD 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 294 CFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGER------Q 367
Cdd:PRK06365  323 AYTSSEIQTYEDLGLCKYGEGGQFIESGKPELPGKLPVNPSGGLLAAGHAVGATGIMQAVFMFWQLQGRIKKHfhddylQ 402

                         410       420
                  ....*....|....*....|...
gi 1101180460 368 VKDAQIGCTHNLGGLGTVVLVNI 390
Cdd:PRK06365  403 VKNAKRGLIHSHAGTGTYVTVTI 425
PRK06059 PRK06059
lipid-transfer protein; Provisional
 8-388 1.49e-73

lipid-transfer protein; Provisional


Pssm-ID: 180373 [Multi-domain]  Cd Length: 399  Bit Score: 234.66  E-value: 1.49e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   8 PVAVVGAGMIKFGElFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAawlgtcIPGTGFRRE----IVTGAGLAEPIRFFP 83
Cdd:PRK06059    5 PVYILGAGMHPWGK-WGRDFVEYGVVAARAALA--DAGLDWRDVQL------VVGADTIRNgypgFVAGATFAQALGWNG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  84 RPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMrdiPSrdSLIAQTG---VAYHSW--WHPRGASAPQRFGSL 158
Cdd:PRK06059   76 APVSSSYAACASGSQALQSARAQILAGLCDVALVVGADTT---PK--GFFAPVGgerPDDPDWlrFHLIGATNPVYFALL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 159 ATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYT 238
Cdd:PRK06059  151 ARRRMDLYGATVEDFAQVKVKNARHGLLNPNARYRKEVTVEDVLASPVVSDPLRLLDICATSDGAAALIVASKSFARRHL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 239 ---DQPLYFLGTGLATdPLFlpwKKNFIEFP--ATQEAAKV--------------AYEMAGIGPDDIDLAELHDCFTITE 299
Cdd:PRK06059  231 gsvAGVPSVRAISTVT-PRY---PQHLPELPdiATDSTAAVpapervfkdqildaAYAEAGIGPEDLSLAEVYDLSTALE 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 300 LLTYEDMGFCKKGEGGKWIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNL 379
Cdd:PRK06059  307 LDWYEHLGLCPKGEAEALLRSGATTLGGRIPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQAGGRQVEGARVGITANQ 386

                         410
                  ....*....|.
gi 1101180460 380 G--GLGTVVLV 388
Cdd:PRK06059  387 GlfGHGSSVIV 397
nondecarbox_cond_enzymes cd00826
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ...
 12-388 1.32e-60

nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.


Pssm-ID: 238422 [Multi-domain]  Cd Length: 393  Bit Score: 200.80  E-value: 1.32e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  12 VGAGMIKFGELFDQSYEDMIVGAYRACLKSVDK-----GIDEKDIEAAWLGTCIPG----TGFRREIVTGAGLAEPirff 82
Cdd:cd00826     1 AGAAMTAFGKFGGENGADANDLAHEAGAKAIAAalepaGVAAGAVEEACLGQVLGAgegqNCAQQAAMHAGGLQEA---- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  83 prPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHSWWHPRGASAPQRFGSLATAH 162
Cdd:cd00826    77 --PAIGMNNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETSAENNAKEKHIDVLINKYGMRACPDAFALAGQAGAEA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 163 MDKFGTKRDHLAMIAVKN---HHNGTLDPYTHFNFEITVEQALNA-PIISWP--LGLFDSCPTTDGAAAILLARQDRAKE 236
Cdd:cd00826   155 AEKDGRFKDEFAKFGVKGrkgDIHSDADEYIQFGDEASLDEIAKLrPAFDKEdfLTAGNACGLNDGAAAAILMSEAEAQK 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 237 YTDQPLyflGTGLATDPLFLPWKKNFIE--------FPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGF 308
Cdd:cd00826   235 HGLQSK---AREIQALEMITDMASTFEDkkvikmvgGDGPIEAARKALEKAGLGIGDLDLIEAHDAFAANACATNEALGL 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 309 CKKGEGGKWIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGLGTVVLV 388
Cdd:cd00826   312 CPEGQGGALVDRGDNTYGGKSIINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRQGAGAGLALLCIGGGGGAAMCI 391
PRK06289 PRK06289
acetyl-CoA acetyltransferase; Provisional
 43-393 1.30e-58

acetyl-CoA acetyltransferase; Provisional


Pssm-ID: 235771 [Multi-domain]  Cd Length: 403  Bit Score: 196.06  E-value: 1.30e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  43 DKGIDEKDIEAAWLGTCIpGTGFRREIVTGAGLAE--PiRFFPRPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGA 120
Cdd:PRK06289   40 AAGVDADDIEVVHVGNFF-GELFAGQGHLGAMPATvhP-ALWGVPASRHEAACASGSVATLAAMADLRAGRYDVALVVGV 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 121 EKMRDIPSRDSlIAQTGVAyhSWWHPRGASA----PQRFGSLATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYTH----- 191
Cdd:PRK06289  118 ELMKTVPGDVA-AEHLGAA--AWTGHEGQDArfpwPSMFARVADEYDRRYGLDEEHLRAIAEINFANARRNPNAQtrgwa 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 192 FNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTD-QPL-YFLGTGLATDPLFLPWKKNFIE----- 264
Cdd:PRK06289  195 FPDEATNDDDATNPVVEGRLRRQDCSQVTDGGAGVVLASDAYLRDYADaRPIpRIKGWGHRTAPLGLEQKLDRSAgdpyv 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 265 FPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKPCNPSGGLKAKGHPI 344
Cdd:PRK06289  275 LPHVRQAVLDAYRRAGVGLDDLDGFEVHDCFTPSEYLAIDHIGLTGPGESWKAIENGEIAIGGRLPINPSGGLIGGGHPV 354

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 1101180460 345 GATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGLGTVVLVNIFGK 393
Cdd:PRK06289  355 GASGVRMLLDAAKQVTGTAGDYQVEGAKTFGTLNIGGSTTTTVSFVVGT 403
PRK06158 PRK06158
thiolase; Provisional
 9-387 3.48e-58

thiolase; Provisional


Pssm-ID: 180434 [Multi-domain]  Cd Length: 384  Bit Score: 194.48  E-value: 3.48e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAawLGTCIPGTGFrreivTGAGLAEPIRFFPRPVsr 88
Cdd:PRK06158   10 TAIVGAATAGLGEAPGLSAMELLAQAAHRALA--DAGLTMADVDG--LFTASPDDAL-----WGLSVAEYLGIRPRFV-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  89 mENACCTGSD---AVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRdsLIAQTGVayhSWW-HPRGASAPQRFGSLATA-HM 163
Cdd:PRK06158   79 -DGTMIGGSSflaHLLPAALALEAGLCDVALICYGSNQRSAGGK--LRSMLDP---QPYeAPYKPVNPVSAYALAAArHM 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 164 DKFGTKRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLY 243
Cdd:PRK06158  153 HQYGTTREQLAEVAVAARQWAQLNPEAFMRDPLTIDDVLAARMVSDPLSVRDCCLVTDGAGAVVMVRADRARDLPRPPVY 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 244 FLGTGLATdplflpWKKNFIEFP-----ATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWI 318
Cdd:PRK06158  233 VLGAAAAT------WHRQISSMPdltvtAAAESGPRAFAMAGLTPADIDVVELYDAFTINTILFLEDLGFCAKGEGGAFV 306

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1101180460 319 EEGHPTLNGTKPCNPSGGLKAKGHPiGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGGL----GTVVL 387
Cdd:PRK06158  307 EGGRIAPGGRLPVNTNGGGLSCVHP-GMYGLFLLIEAVRQLRGEAGERQVAGAEVALAHGNGGVlssqATAIL 378
PRK06065 PRK06065
thiolase domain-containing protein;
9-369 4.61e-56

thiolase domain-containing protein;


Pssm-ID: 180379 [Multi-domain]  Cd Length: 392  Bit Score: 188.88  E-value: 4.61e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGELFDQSYEDMivgAYRACLKSVDK-GIDEKDIEAAWLGTCiPGTgFRREIVTGAGLAEPIRFFPRPVS 87
Cdd:PRK06065   11 VAVIGAGLTLFRRRLLETPQEL---AWEAASKALDEaGLELKDIDCVVIGSA-PDA-FDGVHMKGEYLSHGSGGIRKPVS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  88 RMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRdiPSRdsliAQTGVAYHSWW-----HPRGASAPQRFGSLATAH 162
Cdd:PRK06065   86 RVYVGGATGVMTAIAGWYHVASGLCQKVLAVAEEKMS--PAR----PHPQAVFRYIWdpileKPLNPNLIWIFAMEMHRY 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 163 MDKFGTKRDHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPL 242
Cdd:PRK06065  160 MATYGIKKEEIALVSVKNKRNALNNPYAQLGSKITVEDVLKSEVLVWPVQLLDVSPVSDGAAAIVLASEDLARRYTDTPV 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 243 YFLGTGLATDPLFlpWKKNFIEFPA-TQEAAKVAYEMAGIGP--DDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIE 319
Cdd:PRK06065  240 WVEGVGWTLDNTE--WPNRDLAYPRyVEFAARMAYKMAGIERprKEIDVAEPYDPFDYKELHHLEGLQLAKRGEAPKLLK 317

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 1101180460 320 EGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVK 369
Cdd:PRK06065  318 EGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGTAGKMQVK 367
PRK08313 PRK08313
thiolase domain-containing protein;
8-381 2.83e-50

thiolase domain-containing protein;


Pssm-ID: 181378 [Multi-domain]  Cd Length: 386  Bit Score: 173.76  E-value: 2.83e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   8 PVAVVGAGMIKF-GELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWL--------GTCIPgtgfrrEIVtgagLAEP 78
Cdd:PRK08313    4 LAAVLGTGQTKYvAKRQDVSMAGLVREAIDRALA--DAGLTWDDIDAVVVgkapdffeGVMMP------ELF----LADA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  79 IRFFPRPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPsrdsliAQTGVAYHSWWH-PRGASAPQRFGS 157
Cdd:PRK08313   72 LGATGKPLIRVHTAGSVGGSTAVVAASLVQSGVYRRVLAVAWEKQSESN------AMWALSIPVPFTkPVGAGAGGYFAP 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 158 LATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYTHFNF-EITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKE 236
Cdd:PRK08313  146 HVRAYIRRSGAPEHIGAMVAVKDRLNGAKNPYAHLHQpDITLEKVMASQMLWDPIRFDETCPSSDGACAVVIGDEEAADA 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 237 YTDQPL-YFLGTGLATDPLFLPwKKNFIEFPATQEAAKVAYEMAGI-GP-DDIDLAELHDCFTITELLTYEDMGFCKKGE 313
Cdd:PRK08313  226 AAGRPVaWIHGTAMRTEPLAFA-GRDQVNPQAGRDAAAALWKAAGItDPrDEIDVAEIYVPFSWFEPMWLENLGFAPEGE 304

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 314 GGKWIEEGHPTLNGTKPCNPSGGLKAkGHPIGATGVAQICELWWHLRGEAGERQVKDAQIGCTHNLGG 381
Cdd:PRK08313  305 GWKLTEAGETAIGGRLPVNPSGGVLS-SNPIGASGMIRFAEAALQVMGKAGEHQVDGARKALGHAYGG 371
PRK06066 PRK06066
thiolase domain-containing protein;
100-390 3.03e-45

thiolase domain-containing protein;


Pssm-ID: 180380 [Multi-domain]  Cd Length: 385  Bit Score: 160.30  E-value: 3.03e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 100 VRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAqtgVAYHS-WWHPRGASAPQRFGSL-ATAHMDKFGTKRDHLAMIA 177
Cdd:PRK06066   92 LAHAVMHINSGLANVVVVEAHSKPSDILTFSDVVK---FAMDPiYVRPIGPPNPHFIAGLdAVKFMSRKGITREDLALVV 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 178 VKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTGLATDPLFLP 257
Cdd:PRK06066  169 EKNKKAGLSNPRASYASNISLEDVLSSEYVVYPLTELDIAPFVDGAIVVVLASEEVAKKLTDDPVWIKGIGWSTESSNLE 248

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 258 WKKnFIEFPATQEAAKVAYEMAGIG-PD-DIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKPCNPSG 335
Cdd:PRK06066  249 TAE-LGKANYMRIAADMAYKMAGIEsPRkEVDAAEVDDRYSYKELQHIEALRLSEEPEKDSLLREGNFDPQGELPVNPSG 327

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1101180460 336 GLKAKGHPIGATGVAQICELWWHLRGEAGERQvKDAQIGCTHNLGGL----GTVVLVNI 390
Cdd:PRK06066  328 GHLAKGVPLEASGLSLLLDAVEYLRGEAGARQ-GKAERAVVASWRGIptltGSVVVVER 385
PRK08142 PRK08142
thiolase domain-containing protein;
31-382 1.49e-40

thiolase domain-containing protein;


Pssm-ID: 236164 [Multi-domain]  Cd Length: 388  Bit Score: 147.93  E-value: 1.49e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  31 IVGAY-----RACLKSV-------------DKGIDEKDIEAAWLGTCIPGTGfrreivtGAGLAEPIRFFPRPVSRMENA 92
Cdd:PRK08142    9 IVGAYehptrKAPDKSVaqlhaevakgalaDAGLSLADVDGYFCAGDAPGLG-------PASMVDYLGLKLRHVDSTETG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  93 CCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTG--VAYHSWWHPRGASAPQRFGSLATAHMDKFGTKR 170
Cdd:PRK08142   82 GSSYLAHVGHAAQAIAAGKCSVALITLAGRPRSEGSSGTEPRNWGadAPDAPFEAPYGPTTHNLYAMCAMRHMHEYGTTS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 171 DHLAMIAVKNHHNGTLDPYTHFNFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYTDQPLYFLGTGLA 250
Cdd:PRK08142  162 EQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPMIADPLHRLDCCVVTDGGGALVVVRPEIARSLKRPLVKVLGAGEA 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 251 TD-----PLFLPWKknfiefpATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEGGKWIEEGH-PT 324
Cdd:PRK08142  242 IKgqmggKVDLTYS-------GAAWSGPAAFAEAGVTPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVADGNlIS 314

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1101180460 325 LNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGER-QVKDAQIGCTHNLGGL 382
Cdd:PRK08142  315 GVGKLPFNTDGGGLCNNHPANRGGMTKVIEAVRQLRGEAHPAvQVPNCDLALAHGTGGL 373
PTZ00455 PTZ00455
3-ketoacyl-CoA thiolase; Provisional
 81-391 1.81e-39

3-ketoacyl-CoA thiolase; Provisional


Pssm-ID: 240424 [Multi-domain]  Cd Length: 438  Bit Score: 146.19  E-value: 1.81e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  81 FFPRPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKmrdipsRDSLIAQTGVAYHSwwhpRGAS-APQR----- 154
Cdd:PTZ00455  108 LLYKPAMRVEGACASGGLAVQSAWEALLAGTSDIALVVGVEV------QTTVSARVGGDYLA----RAADyRRQRklddf 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 155 -FGSLATAHMdKFGTKRDHLAM-----IAVKNHHNGTLDPYTH-FNFEITVEQA----------LNAPIISWPLGLFDSC 217
Cdd:PTZ00455  178 tFPCLFAKRM-KYIQEHGHFTMedtarVAAKAYANGNKNPLAHmHTRKLSLEFCtgasdknpkfLGNETYKPFLRMTDCS 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 218 PTTDGAAAILLARQDRAKEYTDQP-----LYFLGTGLATDPLFLPwKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELH 292
Cdd:PTZ00455  257 QVSDGGAGLVLASEEGLQKMGLSPndsrlVEIKSLACASGNLYED-PPDATRMFTSRAAAQKALSMAGVKPSDLQVAEVH 335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 293 DCFTITELLTYEDMGFCKKGEGGKWIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDA- 371
Cdd:PTZ00455  336 DCFTIAELLMYEALGIAEYGHAKDLIRNGATALEGRIPVNTGGGLLSFGHPVGATGVKQIMEVYRQMKGQCGEYQMKNIp 415

                         330       340
                  ....*....|....*....|
gi 1101180460 372 QIGCTHNLGGLGTVVLVNIF 391
Cdd:PTZ00455  416 ALGATLNMGGDDKTAVSTVL 435
PRK07855 PRK07855
lipid-transfer protein; Provisional
 10-371 5.53e-35

lipid-transfer protein; Provisional


Pssm-ID: 181147 [Multi-domain]  Cd Length: 386  Bit Score: 132.79  E-value: 5.53e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  10 AVVGAGMIKFGELFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAawLGTCIPGTGFRREIVTGAGLAEpIRFFPRPVSRM 89
Cdd:PRK07855    7 AIVGIGATEFSKNSGRSELRLACEAVLAALD--DAGLAPSDVDG--LVTFTMDTNPEIAVARALGIGE-LKFFSRIHYGG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  90 ENACCTgsdaVRNAAFAVAAGVYDLVLVVGAEKMR-------DIPSRDSLIAQTGVAYhSWWHPRGASAP-QRFGSLATA 161
Cdd:PRK07855   82 GAACAT----VQQAAMAVATGVADVVVCYRAFNERsgmrfgqGQTGLAENPTSTGVDY-GWSYPHGLLTPaAWVAMLARR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 162 HMDKFGTKRDHLAMIAV--KNHHNGtlDPYTHF-NFEITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYT 238
Cdd:PRK07855  157 YMHEYGATSEDFGRVAVadRKHAAT--NPKAWFyGRPITLEDHQNSRWIAEPLRLLDCCQESDGAVALVVTSAERARDLK 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 239 DQPLYFLGT--GLATDPLFLP--WKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGFCKKGEG 314
Cdd:PRK07855  235 QRPAVIKAAaqGSGADQYMMTsyYRDDITGLPEMGLVARQLWAQSGLGPADIDTAILYDHFTPFVLMQLEELGFCGRGEA 314

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1101180460 315 GKWIEEGHPTLNGTKPCNPSGGLKAKGHPIGATGVAQICELwwhLRGEAgERQVKDA 371
Cdd:PRK07855  315 KDFIADGALELGGRLPINTHGGQLGEAYIHGMNGIAEAVRQ---LRGTS-VNQVPGV 367
thiolase cd00751
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ...
 20-388 4.13e-19

Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.


Pssm-ID: 238383 [Multi-domain]  Cd Length: 386  Bit Score: 87.92  E-value: 4.13e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  20 GELFDQSYEDMIVGAYRACLKSVdkGIDEKDIEAAWLGTCIP-GTGFR--REIVTGAGLAEPIrffprP---VSRMenaC 93
Cdd:cd00751    15 GALKDVSADDLGAAVIKALLERA--GLDPEEVDDVIMGNVLQaGEGQNpaRQAALLAGLPESV-----PattVNRV---C 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  94 CTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIP--SRDSLIAQTGVAYHSWWHPRGASAPqrfgSLATAHM-------- 163
Cdd:cd00751    85 GSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPylLPKARRGGRLGLNTLDGMLDDGLTD----PFTGLSMgitaenva 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 164 DKFGTKR---DHLA----MIAVKNHHNGtldpytHFNFEI---TVEQALNAPIISWPLG---------------LFD--- 215
Cdd:cd00751   161 EKYGISReeqDEFAlrshQRAAAAQEAG------RFKDEIvpvEVPGRKGPVVVDRDEGprpdttleklaklkpAFKkdg 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 216 ------SCPTTDGAAAILLARQDRAKEYTDQPL-YFLGTGLA-TDPLFLPwkknfiEFPAtqEAAKVAYEMAGIGPDDID 287
Cdd:cd00751   235 tvtagnASGINDGAAAVLLMSEEKAKELGLKPLaRIVGYAVAgVDPAIMG------IGPV--PAIPKALKRAGLTLDDID 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 288 LAELHDCFTITELLTYEDMGfckkgeggkwieeghptLNGTKpCNPSGGLKAKGHPIGATGVAQICELwwhlrgeAGERQ 367
Cdd:cd00751   307 LIEINEAFAAQALACLKELG-----------------LDPEK-VNVNGGAIALGHPLGASGARIVVTL-------LHELK 361

                         410       420
                  ....*....|....*....|....*
gi 1101180460 368 VKDAQIG----CthNLGGLGTVVLV 388
Cdd:cd00751   362 RRGGRYGlatmC--IGGGQGAAMVI 384
Thiolase_N pfam00108
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ...
 9-232 5.54e-17

Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.


Pssm-ID: 459676 [Multi-domain]  Cd Length: 260  Bit Score: 80.04  E-value: 5.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   9 VAVVGAGMIKFGE----LFDQSYEDMIVGAYRACLKsvDKGIDEKDIEAAWLGTCI-PGTGFR--REIVTGAGLAEPIrf 81
Cdd:pfam00108   1 VVIVSAARTPFGSfggsLKDVSAVELGAEAIKAALE--RAGVDPEDVDEVIVGNVLqAGEGQNpaRQAALKAGIPDSA-- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  82 fprPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIAQTGVAYHS--------WWHPRGASAPQ 153
Cdd:pfam00108  77 ---PAVTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDARSGLKHGDekkhdlliPDGLTDAFNGY 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 154 RFGSLATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYT-HFNFEI--------------TVEQALNAPIISWPLGLF---- 214
Cdd:pfam00108 154 HMGLTAENVAKKYGISREEQDAFAVKSHQKAAAAPKAgKFKDEIvpvtvkgrkgkptvDKDEGIRPPTTAEPLAKLkpaf 233

                         250       260
                  ....*....|....*....|....*..
gi 1101180460 215 ---------DSCPTTDGAAAILLARQD 232
Cdd:pfam00108 234 dkegtvtagNASPINDGAAAVLLMSES 260
cond_enzymes cd00327
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ...
 212-388 6.11e-17

Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.


Pssm-ID: 238201 [Multi-domain]  Cd Length: 254  Bit Score: 79.80  E-value: 6.11e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 212 GLFDSCPTTDGAAAILLARQDRAKEYTDQPLY-FLGTGLATDPlflPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAE 290
Cdd:cd00327    93 GGSEEFVFGDGAAAAVVESEEHALRRGAHPQAeIVSTAATFDG---ASMVPAVSGEGLARAARKALEGAGLTPSDIDYVE 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 291 LHDCFTITELLTYEDMGFCKKGEGGKWieeghptlngtkpcnPSGGLKAKGHPIGATGVAQICELWWHLRGEAG--ERQV 368
Cdd:cd00327   170 AHGTGTPIGDAVELALGLDPDGVRSPA---------------VSATLIMTGHPLGAAGLAILDELLLMLEHEFIppTPRE 234

                         170       180
                  ....*....|....*....|
gi 1101180460 369 KDAQIGCTHNLGGLGTVVLV 388
Cdd:cd00327   235 PRTVLLLGFGLGGTNAAVVL 254
PRK07937 PRK07937
lipid-transfer protein; Provisional
 159-364 2.27e-16

lipid-transfer protein; Provisional


Pssm-ID: 181173 [Multi-domain]  Cd Length: 352  Bit Score: 79.73  E-value: 2.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 159 ATAHMDKFGTKRDHLAMIAVKNHHNGTLDPYTHFNfeITVEQALNAPIISWPLGLFDSCPTTDGAAAILLARQDRAKEYT 238
Cdd:PRK07937  146 ARAGLDAGKWTEEQMAEVAARSRADARRNPSAEPS--ISVDELLARPYFADPLRRHDIAPITDGAAAVVLAAGDRARELR 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 239 DQPLYFLGTGLATDPLFLPwKKNFIEFPATQEAAKVAyemAGIGPDDIDLAELHDCFTITELLTYEDMGfckkgeggkwi 318
Cdd:PRK07937  224 ERPAWITGIEHRIESPSLG-ARDLTRSPSTALAAEAA---TGGDAGGVDVAELHAPFTHQELILREALG----------- 288

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1101180460 319 eeghptLNGTKPCNPSGGLKAkGHPIGATGVAQICELWWH-LRGEAG 364
Cdd:PRK07937  289 ------LGDKTKVNPSGGALA-ANPMFAAGLERIGEAARHiWDGSAR 328
PRK07801 PRK07801
acetyl-CoA C-acetyltransferase;
13-349 5.58e-15

acetyl-CoA C-acetyltransferase;


Pssm-ID: 181123 [Multi-domain]  Cd Length: 382  Bit Score: 75.90  E-value: 5.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  13 GAGMIKfgELFDQS------YEDMIVGayraCLKSVdkGIDEKDI-EAAWLGtcipgtgfrreivtgAGLAEPIrffprP 85
Cdd:PRK07801   30 GAHVLK--GLVDRTgidpaaVDDVIFG----CVDTI--GPQAGNIaRTSWLA---------------AGLPEEV-----P 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  86 VSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIPSRDSLIA------QTGVAYHSWWHPRGASAP--QRFGS 157
Cdd:PRK07801   82 GVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAMTAgeqlgfTSPFAESKGWLHRYGDQEvsQFRGA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 158 LATAhmDKFGTKRDHLAMIAVKNHH-------NGTLD----PYTHFNF-----EITVEQ--ALNAPIISWPLGLFDSCPT 219
Cdd:PRK07801  162 ELIA--EKWGISREEMERFALESHRrafaairAGRFDneivPVGGVTVdegprETSLEKmaGLKPLVEGGRLTAAVASQI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 220 TDGAAAILLARQDRAKEYTDQPLYFLGT--GLATDPLFL---PwkknfieFPATqeaaKVAYEMAGIGPDDIDLAELHDC 294
Cdd:PRK07801  240 SDGASAVLLASERAVKRHGLTPRARIHHlsVRGDDPVFMltaP-------IPAT----RYALEKTGLSIDDIDVVEINEA 308

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1101180460 295 FTITELltyedmgfckkgeggKWIEEghptlNGTKP--CNPSGGLKAKGHPIGATGV 349
Cdd:PRK07801  309 FAPVVL---------------AWLKE-----TGADPakVNPNGGAIALGHPLGATGA 345
PaaJ COG0183
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ...
 28-348 1.23e-14

Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 439953 [Multi-domain]  Cd Length: 391  Bit Score: 74.72  E-value: 1.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  28 EDMIVGAYRACLKSVdkGIDEKDIEAAWLGTCIP-GTGFR--REIVTGAGLAEPIrffprP---VSRMenaCCTGSDAVR 101
Cdd:COG0183    27 DDLGAAVIKALLERA--GLDPEAVDDVILGCVLQaGQGQNpaRQAALLAGLPESV-----PavtVNRV---CGSGLQAVA 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 102 NAAFAVAAGVYDLVLVVGAEKMRDIP----SRDSLIAQTGVAYHSWWHPRGASAPQRFGSLATAHM--DKFGTKRDHLAM 175
Cdd:COG0183    97 LAAQAIAAGDADVVIAGGVESMSRAPmllpKARWGYRMNAKLVDPMINPGLTDPYTGLSMGETAENvaERYGISREEQDA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 176 IAVKNHH-------NGTLD----PYT--------------HFNFEITVEQ--ALNAPiiswplglFD---------SCPT 219
Cdd:COG0183   177 FALRSHQraaaaiaAGRFDdeivPVEvpdrkgevvvdrdeGPRPDTTLEKlaKLKPA--------FKkdgtvtagnASGI 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 220 TDGAAAILLARQDRAKEYTDQPL-YFLGTGLA-TDPLFLPWkknfiefpATQEAAKVAYEMAGIGPDDIDLAELHDCFTI 297
Cdd:COG0183   249 NDGAAALLLMSEEAAKELGLKPLaRIVAYAVAgVDPEIMGI--------GPVPATRKALARAGLTLDDIDLIEINEAFAA 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1101180460 298 TELLTYEDMGfckkgeggkwieeghptLNGTKpCNPSGGLKAKGHPIGATG 348
Cdd:COG0183   321 QVLAVLRELG-----------------LDPDK-VNVNGGAIALGHPLGASG 353
PRK06205 PRK06205
acetyl-CoA C-acetyltransferase;
5-349 2.19e-09

acetyl-CoA C-acetyltransferase;


Pssm-ID: 235741 [Multi-domain]  Cd Length: 404  Bit Score: 58.85  E-value: 2.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   5 KGLPVAVVGAGMIKfgELFDQSyedmivgayraclksvdkGIDEKDIEAAWLGTC-----IPGTGfrREIVTGAGLaePI 79
Cdd:PRK06205   22 KDVPAEELAATVIR--ALVERT------------------GIDPARIDDVIFGQGypngeAPAIG--RVAALDAGL--PV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  80 RFfprPVSRMENACCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIP--SRDSL--IAQTGVAYH-SWWHPRGASAPQR 154
Cdd:PRK06205   78 TV---PGMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEfyTTDMRwgVRGGGVQLHdRLARGRETAGGRR 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 155 F----GSLATAH--MDKFGTKRDHLAMIAVKNHH-------NGTLD----PYT---------------HFNFEITVEQ-A 201
Cdd:PRK06205  155 FpvpgGMIETAEnlRREYGISREEQDALAVRSHQravaaqeAGRFDdeivPVTvpqrkgdptvvdrdeHPRADTTLESlA 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 202 LNAPIiswpLGLFD---------SCPTTDGAAAILLARQDRAKEYTDQPLYFL-GTGLATDPlflPWKKNFIEFPATQea 271
Cdd:PRK06205  235 KLRPI----MGKQDpeatvtagnASGQNDAAAACLVTTEDKAEELGLRPLARLvSWAVAGVE---PSRMGIGPVPATE-- 305

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 272 akVAYEMAGIGPDDIDLAELHDCFTITELLtyedmgfCKKGEGgkWIEEGHPTLNgtkpCNPSGglKAKGHPIGATGV 349
Cdd:PRK06205  306 --KALARAGLTLDDIDLIELNEAFAAQVLA-------VLKEWG--FGADDEERLN----VNGSG--ISLGHPVGATGG 366
PRK06445 PRK06445
acetyl-CoA C-acetyltransferase;
40-348 2.96e-09

acetyl-CoA C-acetyltransferase;


Pssm-ID: 180563 [Multi-domain]  Cd Length: 394  Bit Score: 58.19  E-value: 2.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  40 KSVDK-GIDEKDIEAAWLGTCIPGT-----GFRREIVTgAGLAEPIrffprPVSRMENACCTGSDAVRNAAFAVAAGVYD 113
Cdd:PRK06445   42 RLIEKtGIKPEEIDDIITGCALQVGenwlyGGRHPIFL-ARLPYNI-----PAMAVDRQCASSLTTVSIGAMEIATGMAD 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 114 LVLVVGAEKMRDIPSRDSLIAQTGVA------YHSWWHPRGASAPQRFGSLATAH------MDKFGTKRDHLAMIAVKNH 181
Cdd:PRK06445  116 IVIAGGVEHMTRTPMGDNPHIEPNPKlltdpkYIEYDLTTGYVMGLTAEKLAEEAgikreeMDRWSLRSHQLAAKAIQEG 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 182 H------------NG---TLDPYTHFNFEITVEQALNAPIISWPLGLF---DSCPTTDGAAAILLARQDRAKEYTDQPLY 243
Cdd:PRK06445  196 YfkdeilpievevEGkkkVVDVDQSVRPDTSLEKLAKLPPAFKPDGVItagNSSPLNSGASYVLLMSKKAVKKYGLKPMA 275

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 244 -FLGTGLATDPlflPWKKNFIEFPATQEAakvaYEMAGIGPDDIDLAELHDCFTITELLTYEDMGfckkgeggkwIEEgh 322
Cdd:PRK06445  276 kIRSFGFAGVP---PAIMGKGPVPASKKA----LEKAGLSVKDIDLWEINEAFAVVVLYAIKELG----------LDP-- 336

                         330       340
                  ....*....|....*....|....*.
gi 1101180460 323 ptlngtKPCNPSGGLKAKGHPIGATG 348
Cdd:PRK06445  337 ------ETVNIKGGAIAIGHPLGATG 356
PLN02644 PLN02644
acetyl-CoA C-acetyltransferase
 34-375 2.48e-08

acetyl-CoA C-acetyltransferase


Pssm-ID: 215347 [Multi-domain]  Cd Length: 394  Bit Score: 55.48  E-value: 2.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  34 AYRACLKSVdkGIDEKDIEAAWLGTCIP---GTGFRREIVTGAGLAEPIrffprPVSRMENACCTGSDAVRNAAFAVAAG 110
Cdd:PLN02644   32 AIQAALERA--GVDPALVQEVFFGNVLSanlGQAPARQAALGAGLPPST-----ICTTVNKVCASGMKAVMLAAQSIQLG 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 111 VYDLVLVVGAEKMRDIP---------SR---DSLIaqTGVAYHSWWHPRGASApqrFGSLATAHMDKFGTKRDHLAMIAV 178
Cdd:PLN02644  105 INDVVVAGGMESMSNAPkylpearkgSRlghDTVV--DGMLKDGLWDVYNDFG---MGVCAELCADQYSISREEQDAYAI 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 179 KNHHNGTLDPYT-HFNFEIT-VEQAL---NAPIISWP---LGLFD----------------------SCPTTDGAAAILL 228
Cdd:PLN02644  180 QSYERAIAAQEAgAFAWEIVpVEVPGgrgRPSVIVDKdegLGKFDpaklrklrpsfkedggsvtagnASSISDGAAALVL 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 229 ARQDRAKEYTDQPLYFL-GTGLATDPLFLpwkknFIEFPATqeAAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMG 307
Cdd:PLN02644  260 VSGEKALELGLQVIAKIrGYADAAQAPEL-----FTTAPAL--AIPKALKHAGLEASQVDYYEINEAFSVVALANQKLLG 332

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 308 fckkgeggkwieeghptLNGTKpCNPSGGLKAKGHPIGATGVAQICELWWHLRGeagerqvKDAQIGC 375
Cdd:PLN02644  333 -----------------LDPEK-VNVHGGAVSLGHPIGCSGARILVTLLGVLRS-------KNGKYGV 375
PRK07851 PRK07851
acetyl-CoA C-acetyltransferase;
217-352 7.35e-08

acetyl-CoA C-acetyltransferase;


Pssm-ID: 181146 [Multi-domain]  Cd Length: 406  Bit Score: 53.85  E-value: 7.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 217 CPTTDGAAAILLARQDRAKEYTDQPL-YFLGTGL-ATDPLflpwkknfIEFPATQEAAKVAYEMAGIGPDDIDLAELHDC 294
Cdd:PRK07851  260 CPLNDGAAAVVIMSDTKARELGLTPLaRIVSTGVsGLSPE--------IMGLGPVEASKQALARAGMSIDDIDLVEINEA 331

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1101180460 295 FTITELLTYEDMGfckkgeggkwIEEghptlngtKPCNPSGGLKAKGHPIGATGvAQI 352
Cdd:PRK07851  332 FAAQVLPSARELG----------IDE--------DKLNVSGGAIALGHPFGMTG-ARI 370
PRK06954 PRK06954
acetyl-CoA C-acetyltransferase;
8-391 7.37e-08

acetyl-CoA C-acetyltransferase;


Pssm-ID: 180775 [Multi-domain]  Cd Length: 397  Bit Score: 54.13  E-value: 7.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460   8 PVAVVGAG---MIKF-GELFDQSYEDMIVGAYRACLKSVdkGIDEKDIEAAWLGTCIP---GTGFRREIVTGAGLaePIR 80
Cdd:PRK06954    8 PIVIASAArtpMAAFqGEFASLTAPQLGAAAIAAAVERA--GLKPEQIDEVVMGCVLPagqGQAPARQAALGAGL--PLS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  81 FFPRPVSRMenaCCTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIP-----SRDSLIAQTGVAYHSWWHPRGASAPQR- 154
Cdd:PRK06954   84 VGCTTVNKM---CGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPyllpkARGGMRMGHGQVLDHMFLDGLEDAYDKg 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 155 --FGSLATAHMDKFGTKR---DHLAMIAVKNHHNGTLDpyTHFNFEI---TVEQALNAPIISWPLGLF----DSCPT--- 219
Cdd:PRK06954  161 rlMGTFAEECAGEYGFTReaqDAFAIESLARAKRANED--GSFAWEIapvTVAGKKGDTVIDRDEQPFkanpEKIPTlkp 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 220 ----------------TDGAAAILLARQDRAKEYTDQPL-YFLG-TGLATDPlflpwkKNFIEFPAtqEAAKVAYEMAGI 281
Cdd:PRK06954  239 afsktgtvtaansssiSDGAAALVMMRASTAKRLGLAPLaRVVGhSTFAQAP------SKFTTAPV--GAIRKLFEKNGW 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 282 GPDDIDLAELHDCFTITELLTYEDMGFCKKgeggkwieeghptlngtkPCNPSGGLKAKGHPIGATGVAQICELWWHLRG 361
Cdd:PRK06954  311 RAAEVDLFEINEAFAVVTMAAMKEHGLPHE------------------KVNVNGGACALGHPIGASGARILVTLIGALRA 372

                         410       420       430
                  ....*....|....*....|....*....|
gi 1101180460 362 EAGERQVKDAQIGcthnlGGLGTVVLVNIF 391
Cdd:PRK06954  373 RGGKRGVASLCIG-----GGEATAMGIELI 397
PRK09052 PRK09052
acetyl-CoA C-acyltransferase;
28-348 3.30e-07

acetyl-CoA C-acyltransferase;


Pssm-ID: 181626 [Multi-domain]  Cd Length: 399  Bit Score: 51.93  E-value: 3.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  28 EDMIVGAYRACLKSVdKGIDEKDIEAAWLGTCIP----GTGFRREIVTGAGLaePIRFFPRPVSRMenaCCTGSDAVRNA 103
Cdd:PRK09052   32 DDLLAHVLRSAVAQV-PGLDPKLIEDAIVGCAMPeaeqGLNVARIGALLAGL--PNSVGGVTVNRF---CASGLQAVAMA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 104 AFAVAAGVYDLVLVVGAEKMRDIP-------------SRDSliaQTGVAYHswwhpRGASA---PQRFGsLATAHMDKFG 167
Cdd:PRK09052  106 ADRIRVGEADVMIAAGVESMSMVPmmgnkpsmspaifARDE---NVGIAYG-----MGLTAekvAEQWK-VSREDQDAFA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 168 TKRDHLAMIAVKN-HHNGTLDPYT---HFNFEITVEQALNAPIISWPLG---------------LF---------DSCPT 219
Cdd:PRK09052  177 LESHQKAIAAQQAgEFKDEITPYEiteRFPDLATGEVDVKTRTVDLDEGpradtsleglaklkpVFankgsvtagNSSQT 256

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 220 TDGAAAILLARQDRAKEYTDQPL-YFLGTGLATDPlflpwkknfiefPATQ-----EAAKVAYEMAGIGPDDIDLAELHD 293
Cdd:PRK09052  257 SDGAGAVILVSEKALKQFNLTPLaRFVSFAVAGVP------------PEIMgigpiEAIPAALKQAGLKQDDLDWIELNE 324

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1101180460 294 CFTITELLTYEDMGfckkgeggkwieeghptLNGTKpCNPSGGLKAKGHPIGATG 348
Cdd:PRK09052  325 AFAAQSLAVIRDLG-----------------LDPSK-VNPLGGAIALGHPLGATG 361
PRK08257 PRK08257
acetyl-CoA acetyltransferase; Validated
 103-295 1.12e-06

acetyl-CoA acetyltransferase; Validated


Pssm-ID: 236204 [Multi-domain]  Cd Length: 498  Bit Score: 50.30  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 103 AAFAVAAGVYDLVLVVGAE---KMRDIPSRDSLIAQTGVAyHSWWHPRGASAPQRFGSLATAH-----MDKFG------- 167
Cdd:PRK08257   99 AALRIAAGEADVALVAGAEaqsTATKLRKAGEKLDWTPQD-EGPLADRGGDPRPMASPAELRHgldrpVYVYPlfenalr 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 168 -----TKRDHLAMI----------AVKNHHNGTLDPYThfNFEITVEQALNAPIiSWP-LGLFDSCPTTD-GAAAIL--L 228
Cdd:PRK08257  178 aalgrSPEEHRAEMgelwapfsavAAKNPHAWIPRERS--AEEIVTPTPDNRMI-AWPyTKLMNANDMVDqGAAVLLtsV 254

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1101180460 229 ARQDRAKEYTDQPLYFLGTGLATDPLFLPWKKNFIEFPATQEAAKVAYEMAGIGPDDIDLAELHDCF 295
Cdd:PRK08257  255 AKARRLGVPEDRWVYLHGGADAHDPYDILERPDLHRSPAIRAAGRRALALAGLGIDDIDAFDLYSCF 321
PRK08235 PRK08235
acetyl-CoA C-acetyltransferase;
221-390 1.75e-06

acetyl-CoA C-acetyltransferase;


Pssm-ID: 181311 [Multi-domain]  Cd Length: 393  Bit Score: 49.71  E-value: 1.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 221 DGAAAILLARQDRAKEYTDQPL-YFLG-TGLATDPlflpwkKNFIEFPAtqEAAKVAYEMAGIGPDDIDLAELHDCFTIT 298
Cdd:PRK08235  252 DGAAALVLMSEDRAKQEGRKPLaTILAhTAIAVEA------KDFPRTPG--YAINALLEKTGKTVEDIDLFEINEAFAAV 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 299 ELLTYEDMGFckkgeggkwieeghptlnGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVkdAQIgCTHn 378
Cdd:PRK08235  324 ALASTEIAGI------------------DPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGI--AAI-CSG- 381

                         170
                  ....*....|..
gi 1101180460 379 lGGLGTVVLVNI 390
Cdd:PRK08235  382 -GGQGDAVLIEV 392
Thiolase_C pfam02803
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ...
 271-388 6.41e-06

Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.


Pssm-ID: 397094 [Multi-domain]  Cd Length: 123  Bit Score: 44.94  E-value: 6.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 271 AAKVAYEMAGIGPDDIDLAELHDCFTITELLTYEDMGfckkgeggkWIEEghptlngtkPCNPSGGLKAKGHPIGATGVA 350
Cdd:pfam02803  27 AIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLG---------IDPE---------KVNVNGGAIALGHPLGASGAR 88

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1101180460 351 QICELWWHLRGEAGERQVKDAQIGcthnlGGLGTVVLV 388
Cdd:pfam02803  89 ILVTLLHELKRRGGKYGLASLCIG-----GGQGVAMII 121
PRK06366 PRK06366
acetyl-CoA C-acetyltransferase;
18-387 2.44e-05

acetyl-CoA C-acetyltransferase;


Pssm-ID: 102340 [Multi-domain]  Cd Length: 388  Bit Score: 46.16  E-value: 2.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  18 KFGELFDQSYEDMIVG-AYRACLKsvDKGIDEKDIEAAWLGTCIP---GTGFRREIVTGAGLAEPIRFFPRPVsrmenAC 93
Cdd:PRK06366   16 KFGRSFSKIKAPQLGGaAIKAVID--DAKLDPALVQEVIMGNVIQagvGQNPAGQAAYHAGLPFGVTKYTVNV-----VC 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460  94 CTGSDAVRNAAFAVAAGVYDLVLVVGAEKMRDIP--------------------SRDSLIAQtGVAYHSWWHPRGASAPQ 153
Cdd:PRK06366   89 ASGMLAVESAAREIMLGERDLVIAGGMENMSNAPfllpsdlrwgpkhllhknykIDDAMLVD-GLIDAFYFEHMGVSAER 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 154 rfgslaTAHmdKFGTKRDHLAMIAVKNHHNGTLDPYT-HFNFEITVEQALN----------APIISWP--------LGLF 214
Cdd:PRK06366  168 ------TAR--KYGITREMADEYSVQSYERAIRATESgEFRNEIVPFNDLDrdegirkttmEDLAKLPpafdkngiLTAG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 215 DSCPTTDGAAAILLARQDRAKEYTDQPLYFLgTGLAT---DPLflpwkkNFIEFPATqeAAKVAYEMAGIGPDDIDLAEL 291
Cdd:PRK06366  240 NSAQLSDGGSALVMASEKAINEYGLKPIARI-TGYESaslDPL------DFVEAPIP--ATRKLLEKQNKSIDYYDLVEH 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 292 HDCFTITELLTYEDMGFckkgeggkwieeghptlnGTKPCNPSGGLKAKGHPIGATGVAQICELWWHLRgeagERQVKDA 371
Cdd:PRK06366  311 NEAFSIASIIVRDQLKI------------------DNERFNVNGGAVAIGHPIGNSGSRIIVTLINALK----TRHMKTG 368

                         410
                  ....*....|....*.
gi 1101180460 372 QIGCTHNLGGLGTVVL 387
Cdd:PRK06366  369 LATLCHGGGGAHTLTL 384
PRK06690 PRK06690
acetyl-CoA C-acyltransferase;
215-387 2.57e-05

acetyl-CoA C-acyltransferase;


Pssm-ID: 180659 [Multi-domain]  Cd Length: 361  Bit Score: 45.91  E-value: 2.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 215 DSCPTTDGAAAILLARQDRAKEYTDQP-LYFLGTGL-ATDPLflpwkknfieFPATQ--EAAKVAYEMAGIGPDDIDLAE 290
Cdd:PRK06690  213 NSCGVNDGACAVLVMEEGQARKLGYKPvLRFVRSAVvGVDPN----------LPGTGpiFAVNKLLNEMNMKVEDIDYFE 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 291 LHDCFTITELLTYEDMGfckkgeggkwIEEGHptlngtkpCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKD 370
Cdd:PRK06690  283 INEAFASKVVACAKELQ----------IPYEK--------LNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIAT 344

                         170
                  ....*....|....*..
gi 1101180460 371 AQIGcthnlGGLGTVVL 387
Cdd:PRK06690  345 LGIG-----GGIGLALL 356
PRK05790 PRK05790
putative acyltransferase; Provisional
 221-348 6.34e-05

putative acyltransferase; Provisional


Pssm-ID: 180261 [Multi-domain]  Cd Length: 393  Bit Score: 44.76  E-value: 6.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 221 DGAAAILLARQDRAKEYTDQPLYFLG----TGLatDPLFL---PwkknfieFPATQEAAkvayEMAGIGPDDIDLAELHD 293
Cdd:PRK05790  252 DGAAAVVVMSEAKAKELGLTPLARIVsyavAGV--DPAIMgigP-------VPAIRKAL----EKAGWSLADLDLIEINE 318

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1101180460 294 CFTITELLTYEDMGFckkgeggkwieeghptlnGTKPCNPSGGLKAKGHPIGATG 348
Cdd:PRK05790  319 AFAAQALAVEKELGL------------------DPEKVNVNGGAIALGHPIGASG 355
PRK06633 PRK06633
acetyl-CoA C-acetyltransferase;
215-388 7.39e-04

acetyl-CoA C-acetyltransferase;


Pssm-ID: 168632 [Multi-domain]  Cd Length: 392  Bit Score: 41.55  E-value: 7.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 215 DSCPTTDGAAAILLARQDRAKEYTDQPLYFLGT--GLATDPLflpwkknfIEFPATQEAAKVAYEMAGIGPDDIDLAELH 292
Cdd:PRK06633  245 NASSINDGAACLMVVSEEALKKHNLTPLARIVSyaSAGVDPS--------IMGTAPVPASQKALSKAGWSVNDLEVIEVN 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 293 DCFTITELLTYEDMgfckkgeggKWIEEghptlngtkPCNPSGGLKAKGHPIGATGVAQICELWWHLRGEAGERQVKDAQ 372
Cdd:PRK06633  317 EAFAAQSIYVNREM---------KWDME---------KVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLC 378

                         170
                  ....*....|....*.
gi 1101180460 373 IGcthnlGGLGTVVLV 388
Cdd:PRK06633  379 IG-----GGMGMAMCV 389
PRK07661 PRK07661
acetyl-CoA C-acetyltransferase;
215-348 1.64e-03

acetyl-CoA C-acetyltransferase;


Pssm-ID: 181072 [Multi-domain]  Cd Length: 391  Bit Score: 40.12  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 215 DSCPTTDGAAAILLARQDRAKEYTDQPLY-FLGTGLATDPlflpwkknfiefPATQ-----EAAKVAYEMAGIGPDDIDL 288
Cdd:PRK07661  244 NSSQMSDGAAAVLLMDREKAESDGLKPLAkFRSFAVAGVP------------PEVMgigpiAAIPKALKLAGLELSDIGL 311

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1101180460 289 AELHDCFTITELLTYEDMGfckkgeggkwieeghptLNGTKpCNPSGGLKAKGHPIGATG 348
Cdd:PRK07661  312 FELNEAFASQSIQVIRELG-----------------LDEEK-VNVNGGAIALGHPLGCTG 353
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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