|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
13-405 |
2.10e-85 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 266.72 E-value: 2.10e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 13 LKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKAN-SIILGSSCF 91
Cdd:cd13128 2 AKNSGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFSIFADLGLPTALVREIARYRKEKiREIISTSLV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 92 LQVVGSVLASILVLITVFALKPGDWDLFWAALVMIPSVLLRTSDIYKYW-FESQVLAKYTVLAQSIAFFGSAIFKILVIV 170
Cdd:cd13128 82 LKLILGILALLLLFLFAFLIAFYDPELVLLLYILALSLPFSALNSLFRGiFQGFEKMKYIVIARIIESVLSLILALILVL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 171 NGGSYLYICASVSLEALILAIGLSYFFSKKGVR-DTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGNMLNASA 249
Cdd:cd13128 162 LGGGLIGFALAYLIASVLSAILLLYIYRKKILLpKFFSFDLKLAKELLRFSIPLALSGIFSLIYTRIDTIMLGYFLGDAA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 250 VGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKLREISIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYTKDYSD 329
Cdd:cd13128 242 VGIYNAAYRIAELLLFIPSAISTALFPRISELYKNDKDELKKLLKKSFKYLFLISLPIAIGLFLFAEPIITLLFGEEYLP 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1098933979 330 ASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPIYGIIGSVYATLVAYACAGYLF 405
Cdd:cd13128 322 AALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALLNVILNLLLIPKYGIIGAAIATLISEFIIFILL 397
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
10-405 |
4.28e-43 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 155.11 E-value: 4.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 10 SRSLKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKAN-SIILGS 88
Cdd:COG2244 2 KKLLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLFALALSIVALLSVLADLGLSTALVRFIAEYREEElRRLLST 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 89 SCFLQVVGSVLASILVLITVFALKP--GDWDLFWAALVMIPSVLLRT-SDIYKYWFESQVLAKYTVLAQSIAFFGSAIFK 165
Cdd:COG2244 82 ALLLRLLLSLLLALLLLLLAPFIAAllGEPELALLLLLLALALLLSAlSAVLLALLRGLERFKLLALINILSSLLSLLLA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 166 ILVIVNGGSYLYIcasvslealilaiglsyffskkgvrdtwklnfteakrLLSQSWPLIISGVAFMLYMRIDQVMIGNML 245
Cdd:COG2244 162 LLLALLGLGLWGL-------------------------------------VLKYSLPLLLSGLLGLLLTNLDRLLLGALL 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 246 NASAVGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKL-REISIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYT 324
Cdd:COG2244 205 GPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLlAEGDREELRRLYRKALRLLLLLGLPLALGLALLAPPLLSLLFG 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 325 KDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPIYGIIGSVYATLVAYACAGYL 404
Cdd:COG2244 285 PEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNLLLIPRYGLVGAAIATLLSYLVLLLL 364
|
.
gi 1098933979 405 F 405
Cdd:COG2244 365 L 365
|
|
| Polysacc_synt |
pfam01943 |
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. ... |
12-281 |
3.97e-18 |
|
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis, which is involved in spore cortex biosynthesis.
Pssm-ID: 426523 [Multi-domain] Cd Length: 274 Bit Score: 83.89 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 12 SLKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKAN---SIILGS 88
Cdd:pfam01943 1 LLKNVIVLLLSQLITYLLAFVTLPYLARILGPEGFGLYAFALAFVGLLTIFTDFGFNAALVREIAKYREKYelvSLYWLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 89 SCFLQVVGSVLASILVLITVFALKPGDWDLFWAALVMIPsvLLRTSDIYKYWFESQV-LAKYTVLAQSIAFFGSAIFKIL 167
Cdd:pfam01943 81 ALLVKLVLVLLFLLLPLIAAFLGLPELAVLYRILALMFL--LLPGVVQFRRGLFQGLeRMKYALISQIVESLSRVILVFI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 168 VIVNGGSYLYICASVSLEALILAIGLSYFFSKKGVRDTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGNMLNA 247
Cdd:pfam01943 159 AVFLPGDIVAALLYQVLAALVGGIIALAVLRKIFRPRFVFPSLKLVRKLLSFGAPLFISSLAISLYTYIDSILLGLLLGA 238
|
250 260 270
....*....|....*....|....*....|....*.
gi 1098933979 248 SAVGVYSVAVK--MVEVWYFFPIAiVSTLFPKIIKL 281
Cdd:pfam01943 239 GAVGIYNAAYQllVAIQGLLNPIV-TAVLFPVFSKL 273
|
|
| spore_V_B |
TIGR02900 |
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial ... |
13-397 |
3.68e-06 |
|
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial endopore formation program in Bacillus subtilis and various other Firmcutes. It is nearly universal among endospore-formers. Paralogs with rather high sequence similarity to SpoVB exist, including YkvU in B. subtilis and a number of proteins in the genus Clostridium. [Cellular processes, Sporulation and germination]
Pssm-ID: 274343 [Multi-domain] Cd Length: 488 Bit Score: 49.21 E-value: 3.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 13 LKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDE------KANSIIL 86
Cdd:TIGR02900 2 LKGTFILTIANLITRILGFIFRIVLSRILGAEGVGLYGMAMPIYFLFITLTTGGLPVAISKFVAEASakndrkNIKKILK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 87 GSSCFLQVVGSVLASILVL----ITVFALKpgDWDLFWAALVMIPSVLLRT-SDIYKYWFES----QVLAKYTVLAQSIA 157
Cdd:TIGR02900 82 VSLIFTLIWSLIVTAIVFLlspfIASTLLK--DERSLYSLLVICPAMPFIAlSSVLKGYFQGisnmKPPAYIQVIEQIVR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 158 FFGSAIFKILVIVNGGSYLYICASVSL---EALILAIGLSYFFSKKGVRDTWKLNFTE------AKRLLSQSWPLIISGV 228
Cdd:TIGR02900 160 ISVVALLISAFLPYGLEYAVAGAYLSLvlgELVSLLYLYFFFKRKKSFSIRFPFFDYKsegkalLFDLFSVSLPLTLSRF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 229 AFMLYMRIDQVMIGNMLNASAVgVYSVAVK-------MVEVWYFFPIAIVS----TLFPKI---IKLREISIEKYHQRLQ 294
Cdd:TIGR02900 240 IGSLLYFLETLLVPQRLVIAGV-TYREATSlygklsgMAMPLLTFPAVITSslstALVPDIseaMAKKNYSSIEKRINQA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 295 FLYDLLVVISVVIALFVtfLSDYIIDFFYtkDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIG 374
Cdd:TIGR02900 319 IKISLLLGLITTVILLV--IPDELGALFY--GRPDAGNFIRVLAPSFPFLYFSAPLQSILQGLGKQKVALRNSLIGAIVK 394
|
410 420
....*....|....*....|....*
gi 1098933979 375 VTLNYVL--IPIYGIIGSVYATLVA 397
Cdd:TIGR02900 395 IILLFVLtsIPSINIYGYAITFIIT 419
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
13-405 |
2.10e-85 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 266.72 E-value: 2.10e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 13 LKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKAN-SIILGSSCF 91
Cdd:cd13128 2 AKNSGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFSIFADLGLPTALVREIARYRKEKiREIISTSLV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 92 LQVVGSVLASILVLITVFALKPGDWDLFWAALVMIPSVLLRTSDIYKYW-FESQVLAKYTVLAQSIAFFGSAIFKILVIV 170
Cdd:cd13128 82 LKLILGILALLLLFLFAFLIAFYDPELVLLLYILALSLPFSALNSLFRGiFQGFEKMKYIVIARIIESVLSLILALILVL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 171 NGGSYLYICASVSLEALILAIGLSYFFSKKGVR-DTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGNMLNASA 249
Cdd:cd13128 162 LGGGLIGFALAYLIASVLSAILLLYIYRKKILLpKFFSFDLKLAKELLRFSIPLALSGIFSLIYTRIDTIMLGYFLGDAA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 250 VGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKLREISIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYTKDYSD 329
Cdd:cd13128 242 VGIYNAAYRIAELLLFIPSAISTALFPRISELYKNDKDELKKLLKKSFKYLFLISLPIAIGLFLFAEPIITLLFGEEYLP 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1098933979 330 ASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPIYGIIGSVYATLVAYACAGYLF 405
Cdd:cd13128 322 AALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALLNVILNLLLIPKYGIIGAAIATLISEFIIFILL 397
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
10-405 |
4.28e-43 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 155.11 E-value: 4.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 10 SRSLKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKAN-SIILGS 88
Cdd:COG2244 2 KKLLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLFALALSIVALLSVLADLGLSTALVRFIAEYREEElRRLLST 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 89 SCFLQVVGSVLASILVLITVFALKP--GDWDLFWAALVMIPSVLLRT-SDIYKYWFESQVLAKYTVLAQSIAFFGSAIFK 165
Cdd:COG2244 82 ALLLRLLLSLLLALLLLLLAPFIAAllGEPELALLLLLLALALLLSAlSAVLLALLRGLERFKLLALINILSSLLSLLLA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 166 ILVIVNGGSYLYIcasvslealilaiglsyffskkgvrdtwklnfteakrLLSQSWPLIISGVAFMLYMRIDQVMIGNML 245
Cdd:COG2244 162 LLLALLGLGLWGL-------------------------------------VLKYSLPLLLSGLLGLLLTNLDRLLLGALL 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 246 NASAVGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKL-REISIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYT 324
Cdd:COG2244 205 GPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLlAEGDREELRRLYRKALRLLLLLGLPLALGLALLAPPLLSLLFG 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 325 KDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPIYGIIGSVYATLVAYACAGYL 404
Cdd:COG2244 285 PEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNLLLIPRYGLVGAAIATLLSYLVLLLL 364
|
.
gi 1098933979 405 F 405
Cdd:COG2244 365 L 365
|
|
| MATE_tuaB_like |
cd13127 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This ... |
13-401 |
1.87e-22 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240532 [Multi-domain] Cd Length: 406 Bit Score: 98.71 E-value: 1.87e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 13 LKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKANSIILGSscfl 92
Cdd:cd13127 2 VSGAFWSAISQVVVQLLQFVVTIILARLLTPEDFGLVAMATVFIAFAQLFSDLGLSSALIQRKDLTEEDLSTVFWL---- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 93 qvvgSVLASILVLITVFALKP------GDWDLFWAALVMIPSVLLRT-SDIYKYWFESQVLAKYTVLAQSIAFFGSAIFK 165
Cdd:cd13127 78 ----NLLLGLLLYLLLFLLAPliaafyNEPELIPLLRVLSLSFLLSGlGSVPRALLQRELRFKKLAIIELISTLVSGVVA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 166 ILVIVNGGSYLYICASVSLEALILAIgLSYFFSKKGVRdtWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGNML 245
Cdd:cd13127 154 IVLALLGFGVWALVAQQLVGALVSTV-LLWILSRWRPR--LSFSLASLKELLSFGSKLLGSNLLNYFSRNLDNLIIGKFL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 246 NASAVGVYSVAVKmvevWYFFPIAIVST-----LFPKIIKLREiSIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIID 320
Cdd:cd13127 231 GAAALGYYSRAYR----LALLPVQNITGpitrvLFPALSRLQD-DPERLRRAYLKALRLLALITFPLMVGLALLAEPLVL 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 321 FFYTKDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPiYGIIGSVYATLVAYAC 400
Cdd:cd13127 306 LLLGEKWLPAVPILQILALAGLFQPLSSLNGSLLLALGRTDLLLKLGLIKAVLTVLALLIGIP-YGIIGVAIAYVIASLL 384
|
.
gi 1098933979 401 A 401
Cdd:cd13127 385 S 385
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
17-404 |
1.29e-20 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 93.69 E-value: 1.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 17 VWLSADSL-TRMgLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVR------ELIKDEKANSIILGSS 89
Cdd:cd13124 1 LILTIAGLiSKI-LGAIYRIPLQNIIGDEGMGLYQMAYPIYGIFLTLATAGIPVAISKlvaeynALGDYKGARRIFRVSL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 90 CFLQVVGSVLASILVLITVF--ALKPGDWDLFWAALVMIPSVLLRT-SDIYKYWFESQVLAKYTVLAQSIAFFGSAIFKI 166
Cdd:cd13124 80 ILLLILGLVFFLLLFFGAPFlaQLLLGDPRLAPVIRALAPAILIVPlLSVLRGYFQGLQNMTPTAVSQVIEQIVRVIVIL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 167 ----LVIVNGGSYLYICASVSLEALILAIG----LSYFFSKKGVRDTWKLNFTEA---------KRLLSQSWPLIISGVA 229
Cdd:cd13124 160 vlayLLLPVGGGLYYAAAGATFGAVIGALAgllvLLYYYRKKRRELKRLLRKSPRskistkeilKELLSYAIPITLSSLI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 230 FMLYMRIDQVMIGNMLNASAV---------GVYS-VAVKMVEVWYFFPIAIVSTLFPKIIKLREI-SIEKYHQRLQFLYD 298
Cdd:cd13124 240 LPLLQLIDSFTVPRRLQAAGLseseatalyGILTgRAQPLVQLPTVIATALSTSLVPAISEAYAKgDKKELRRRINQALR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 299 LLVVISVVIALFVTFLSDYIIDFFYTkdYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLN 378
Cdd:cd13124 320 LTLLIGLPAAVGLAVLAEPINTLLFG--DSEGGLILQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLN 397
|
410 420
....*....|....*....|....*.
gi 1098933979 379 YVLIPIYGIIGSVYATLVAYACAGYL 404
Cdd:cd13124 398 YVLIPIFGIYGAAIATVIGFLVAALL 423
|
|
| Polysacc_synt |
pfam01943 |
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. ... |
12-281 |
3.97e-18 |
|
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis, which is involved in spore cortex biosynthesis.
Pssm-ID: 426523 [Multi-domain] Cd Length: 274 Bit Score: 83.89 E-value: 3.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 12 SLKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDEKAN---SIILGS 88
Cdd:pfam01943 1 LLKNVIVLLLSQLITYLLAFVTLPYLARILGPEGFGLYAFALAFVGLLTIFTDFGFNAALVREIAKYREKYelvSLYWLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 89 SCFLQVVGSVLASILVLITVFALKPGDWDLFWAALVMIPsvLLRTSDIYKYWFESQV-LAKYTVLAQSIAFFGSAIFKIL 167
Cdd:pfam01943 81 ALLVKLVLVLLFLLLPLIAAFLGLPELAVLYRILALMFL--LLPGVVQFRRGLFQGLeRMKYALISQIVESLSRVILVFI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 168 VIVNGGSYLYICASVSLEALILAIGLSYFFSKKGVRDTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGNMLNA 247
Cdd:pfam01943 159 AVFLPGDIVAALLYQVLAALVGGIIALAVLRKIFRPRFVFPSLKLVRKLLSFGAPLFISSLAISLYTYIDSILLGLLLGA 238
|
250 260 270
....*....|....*....|....*....|....*.
gi 1098933979 248 SAVGVYSVAVK--MVEVWYFFPIAiVSTLFPKIIKL 281
Cdd:pfam01943 239 GAVGIYNAAYQllVAIQGLLNPIV-TAVLFPVFSKL 273
|
|
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
13-425 |
5.10e-18 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 86.37 E-value: 5.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 13 LKNIVWLSADSL-TRMgLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVV---VRELI---KDEKANSII 85
Cdd:COG5841 7 LKGALILTAAGLiSKI-LGAIYRIPLQNIIGDEGFGLYQMAYPIYGLFLTLATAGIPVAIsklVAEYNalgDYKGARRIF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 86 LGSSCFLQVVGSVLASILVL----ITVFALkpGDWDLFWAALVMIPSVLLRT-SDIYKYWFESQVLAKYTVLAQSIaffg 160
Cdd:COG5841 86 RVSLLLLLILGLVFFLLLFFgapfIARLLL--GDPRAYYSLRALAPALLIVPvMSVLRGYFQGLQNMTPTAVSQVI---- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 161 SAIFKILVIVnGGSYL-------YICASVSLEALILAIG----LSYFFSKKGVRDTWKLNFTE----------AKRLLSQ 219
Cdd:COG5841 160 EQIVRVIFIL-LLAYLllpygleYAAAGATFGAVIGALAgllvLLYYYRKRKKKLKRLLEKSKtkskesskdiLKELLRI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 220 SWPLIISGVAFMLYMRIDQVMIGNMLNA---------SAVGVYS-VAVKMVEVWYFFPIAIVSTLFPKIIKLREIS-IEK 288
Cdd:COG5841 239 AIPITLSSLVLPLFQLIDSFTVPRRLQAaglsaseatSLYGILSgMAQPLVNLPTVLATALATSLVPAISEAFAKKdRKL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 289 YHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYtkDYSDASIVIKLYSWVSVFYFLSSASGrwYINEGL--QKYALNR 366
Cdd:COG5841 319 VRRRINQALRLTLLIGLPAAVGLAVLAEPINTLLF--GNPEGGGILAILAPSAIFLSLQQVTT--GILQGLgkQKIPVIN 394
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 367 NILGLIIGVTLNYVLIPIYGIIGSVYATLVAYACAGYL-FDSLTHHTRISFIQKTKALWL 425
Cdd:COG5841 395 LLIGLLVKIILNYLLVPLFGIYGAALATVIGYLVAAILnLAALKKYTGFKLDLRRRLLKP 454
|
|
| MATE_like_10 |
cd13125 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This ... |
14-400 |
5.62e-16 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This family might function as a translocase for lipopolysaccharides, such as O-antigen. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240530 [Multi-domain] Cd Length: 409 Bit Score: 79.51 E-value: 5.62e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 14 KNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVR---ELIKDEKANSIILGSSC 90
Cdd:cd13125 1 KVSSLSGISTLIKILAGLIINKVVAVYLGPSGVALLGQLQNFVTILQTIAGGGINNGVVKytaEYKDDEEKLARVWSTAF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 91 FLQVVGSVLASILVLITVFALKP---GDWDLFWAALVMIPSVLLRT-SDIYKYWFESQVLAKYTVLAQSIAFFGSAIFKI 166
Cdd:cd13125 81 RITLILSILGGLLLLLFSKPLSSllfGDIDYSWVFILLGLALPLFAlNNLLLAILNGLKEIKRYALINIISSLIGLLVSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 167 LVIVNGGSYLYICASVSLEALILAIGLSYFFS---KKGVRDTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGN 243
Cdd:cd13125 161 LLVYFYGLKGALLALVLNQSLIFLVTLIYSRKqpwFKLKYLWGRLDKDIIKKLLKFSLMALVSALSLPLSQIIVRNILIR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 244 MLNASAVGVYSVAVKMVEVWYFFPIAIVSTLF-PKIIKLREISIEKYHQRLQFLYDLLVVISVVIALFvtFLSDYIIDFF 322
Cdd:cd13125 241 QLGWEAAGYWQAVWKISDVYLGFITTALSTYYlPRLSAIKDNKELKREVNKQLKVILPLVAIGALLIY--LLRDLIIQIL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 323 YTKDYSDAS---------IVIKLYSWVSVFYFLSSASGRWYINEGlqkyalnrnILGLIIGVTLNYVLIPIYGIIGSVYA 393
Cdd:cd13125 319 FSEEFLPARelflwqligDFFKIASWLLGYILLAKGMTKLFIITE---------ILFALLFVLLSLLFIPLFGLEGAGIA 389
|
....*..
gi 1098933979 394 TLVAYAC 400
Cdd:cd13125 390 YAINYIL 396
|
|
| MATE_epsE_like |
cd13129 |
Multidrug and toxic compound extrusion family and similar proteins; This model represents a ... |
11-400 |
7.53e-15 |
|
Multidrug and toxic compound extrusion family and similar proteins; This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins, including Ralstonia solanaceraum GMI1000 epsE, which may be involved in exporting exopolysaccharide EPS I, a virulence factor. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240534 [Multi-domain] Cd Length: 411 Bit Score: 75.99 E-value: 7.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 11 RSLKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMN---GVVVREL--IKDEKANSII 85
Cdd:cd13129 1 SFASGSFWSLGGLVASRGAVFLTNIMVARSLGKHVFGEFGVIQVTIGLLGTFAGFGLGlaaTKVIAETkdVDPERAGRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 86 LGSSCFLQVVGSVLASILVL------ITVFALKPGDWDLFWAALVMIPSVLLRTSDIYKYWFES-QVLAKYTVLAqsiAF 158
Cdd:cd13129 81 GLSILLAVVTGALAATVLFLsatwiaIATLNAPHLAELLRIAAIILILTAFTGAQTGFLSGFEAfRAIARVNIWA---GL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 159 FGSAIFKILVIVNG--GSYLYICASVSLEALILAIGLSYFFSKKGVRDTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRI 236
Cdd:cd13129 158 LLLPLMWIGVYIRGlvGAVVILLASAAGNVASNSLILRRECQNQRGPVRTGLTWQELRVLFKFSLPSVLSGSMGSPVHWI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 237 DQVMIGNMLN-ASAVGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKLREISIEKYHQRLQFLYDLLVVISVVIALFVTFLS 315
Cdd:cd13129 238 ALAILVNQPNgYAELGLFNAANQWRQFITFLPATLGNVALPFLAENFGNNEGMFRQTFRSALLFGLGLSLPLGCVFILAS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 316 DyIIDFFYTKDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPIYGIIGSVYATL 395
Cdd:cd13129 318 Q-IFAWLYGKEYGSAAASMRSLAVAAILVGLSVLLGQIIASSGKIWRGFALNMVWSVIYVAAAYLLLRLYGAPGLALAMS 396
|
....*
gi 1098933979 396 VAYAC 400
Cdd:cd13129 397 AAYCV 401
|
|
| Polysacc_synt_3 |
pfam13440 |
Polysaccharide biosynthesis protein; |
37-331 |
2.03e-12 |
|
Polysaccharide biosynthesis protein;
Pssm-ID: 404342 [Multi-domain] Cd Length: 293 Bit Score: 67.62 E-value: 2.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 37 LARYLGPEKFGIYnyalAIITIFVSVASLGMNGVVVRELIKDEKANSIiLGSSCF-LQVVGSVLASILVLITVFAL---- 111
Cdd:pfam13440 2 LARLLSPEDFGVV----AIATVVISFANIFVDMGFSSALIQKKDITET-DYSTVFtFNLIFGALIYLILFALAPLIasfy 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 112 -KPGDWDLFW-AALVMIPSVLLRTSD-IYKYWFESQVLAKYTVLAQSIAFfgsaIFKILVIVNGGSYLYICASVSLEALI 188
Cdd:pfam13440 77 nQPELVPVLRvLALVLILNGLSSVQTaLLRRDLRFKKLFKITLTSSVIGG----IVGIVLAYLGFGVWALVIGTLAQQLL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 189 LAIGLsYFFSKKgvRDTWKLNFTEAKRLLSQSWPLIISGVAFMLYMRIDQVMIGNMLNASAVGVYSVAVKMVEVWYFFPI 268
Cdd:pfam13440 153 SLVLL-WLASDW--RPRLTFSLKVIKELFSFGSWLLLSNLLNYLARNLDNLIIGKVLGTAALGLYSVAYRLALLPTANIT 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1098933979 269 AIVST-LFPKIIKLREIS---IEKYHQRLQFlydlLVVISVVIALFVTFLSDYIIDFFYTKDYSDAS 331
Cdd:pfam13440 230 SVITKvLFPALSRIQDDKaklRELYLRVLRL----IAFIVFPIMAGLAVVAEPLVLVLLGSQWLESV 292
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
214-401 |
1.65e-07 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 53.22 E-value: 1.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 214 KRLLSQSWPLIISGVAFMLYMRIDQVMIGNmLNASAVGVYSVAVKMVEVWYFFPIAIVSTLFPKI-IKLREISIEKYHQR 292
Cdd:COG0534 8 KLLLRLALPIILGNLLQSLYGLVDTIFVGR-LGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVaQALGAGDREEARRV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 293 LQFLYDLLVVISVVIALFVTFLSDYIIDFFYTKD--YSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILG 370
Cdd:COG0534 87 LGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPevLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLIG 166
|
170 180 190
....*....|....*....|....*....|...
gi 1098933979 371 LIIGVTLNYVLI--PIYGIIGSVYATLVAYACA 401
Cdd:COG0534 167 NVLNIVLDPLLIfgGGLGVAGAALATVISQAVS 199
|
|
| spore_V_B |
TIGR02900 |
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial ... |
13-397 |
3.68e-06 |
|
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial endopore formation program in Bacillus subtilis and various other Firmcutes. It is nearly universal among endospore-formers. Paralogs with rather high sequence similarity to SpoVB exist, including YkvU in B. subtilis and a number of proteins in the genus Clostridium. [Cellular processes, Sporulation and germination]
Pssm-ID: 274343 [Multi-domain] Cd Length: 488 Bit Score: 49.21 E-value: 3.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 13 LKNIVWLSADSLTRMGLGFLVSVWLARYLGPEKFGIYNYALAIITIFVSVASLGMNGVVVRELIKDE------KANSIIL 86
Cdd:TIGR02900 2 LKGTFILTIANLITRILGFIFRIVLSRILGAEGVGLYGMAMPIYFLFITLTTGGLPVAISKFVAEASakndrkNIKKILK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 87 GSSCFLQVVGSVLASILVL----ITVFALKpgDWDLFWAALVMIPSVLLRT-SDIYKYWFES----QVLAKYTVLAQSIA 157
Cdd:TIGR02900 82 VSLIFTLIWSLIVTAIVFLlspfIASTLLK--DERSLYSLLVICPAMPFIAlSSVLKGYFQGisnmKPPAYIQVIEQIVR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 158 FFGSAIFKILVIVNGGSYLYICASVSL---EALILAIGLSYFFSKKGVRDTWKLNFTE------AKRLLSQSWPLIISGV 228
Cdd:TIGR02900 160 ISVVALLISAFLPYGLEYAVAGAYLSLvlgELVSLLYLYFFFKRKKSFSIRFPFFDYKsegkalLFDLFSVSLPLTLSRF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 229 AFMLYMRIDQVMIGNMLNASAVgVYSVAVK-------MVEVWYFFPIAIVS----TLFPKI---IKLREISIEKYHQRLQ 294
Cdd:TIGR02900 240 IGSLLYFLETLLVPQRLVIAGV-TYREATSlygklsgMAMPLLTFPAVITSslstALVPDIseaMAKKNYSSIEKRINQA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 295 FLYDLLVVISVVIALFVtfLSDYIIDFFYtkDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIG 374
Cdd:TIGR02900 319 IKISLLLGLITTVILLV--IPDELGALFY--GRPDAGNFIRVLAPSFPFLYFSAPLQSILQGLGKQKVALRNSLIGAIVK 394
|
410 420
....*....|....*....|....*
gi 1098933979 375 VTLNYVL--IPIYGIIGSVYATLVA 397
Cdd:TIGR02900 395 IILLFVLtsIPSINIYGYAITFIIT 419
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
214-401 |
6.19e-06 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 48.28 E-value: 6.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 214 KRLLSQSWPLIISGVAFMLYMRIDQVMIGnMLNASAVgvysVAVKMVEVWYFFPIAIVSTLFPKIIKL--REISIEKYHQ 291
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVG-RLGAEAI----AAVGLATQVLWLLLVLNMALGTGTVALvsQSYGAGDYER 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 292 RLQFLYDLLV---VISVVIALFVTFLSDYIIDFFYTKD--YSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNR 366
Cdd:cd13137 76 ARRALGQSLLlalLLSLPLALLGLLFAEPLLRLLGADPevIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYI 155
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1098933979 367 NILGLIIGVTLNYVLI------PIYGIIGSVYATLVAYACA 401
Cdd:cd13137 156 MIIVNVLNIVLDYVLIfglwgfPGLGVAGAALATVISRVVG 196
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
222-380 |
1.12e-04 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 42.55 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 222 PLIISGVAFMLYMRIDQVMIGnMLNASAVGVYSVAVKMVEVWYFFPIAIVSTLfpKIIKLREISIEKYH---QRLQFLYD 298
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVG-HLGAVALAAVSIANSIASLIFMFLLGLGTAL--TTLVGQALGAGNFKragVALRQGLI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 299 LLVVISVVIALFVTFLSDYIIDFFYTKD--YSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVT 376
Cdd:pfam01554 78 LGLLLSLPIALLVLLFSEPILSLFGQDEevLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIP 157
|
....
gi 1098933979 377 LNYV 380
Cdd:pfam01554 158 LNYL 161
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
301-405 |
1.25e-04 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 44.05 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 301 VVISVVIALFVTFLSDYIIDFFYTKD---YSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTL 377
Cdd:cd13140 92 LLLGILYGLLLLLFAKPLIGFFNLGDaevISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFIINAIGLVLNIIL 171
|
90 100 110
....*....|....*....|....*....|....
gi 1098933979 378 NYVLI------PIYGIIGSVYATLVAYACAGYLF 405
Cdd:cd13140 172 DPLLIfgfgpfPALGVAGAALATVLAQAIVFLLF 205
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
20-405 |
4.60e-04 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 42.31 E-value: 4.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 20 SADSLTRMGLGFLVSVWLARYLGP------EKFGIYNYALAIITIFVSVASLGMNGVVVRELIKD--EKANSIILGSSCF 91
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRllgdalAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGdeEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 92 LQVVGSVLASILVLITVFALKPGDWD----------LFWAALVMIPSVLlrtSDIYKYWFESQVLAKYTVLAQSIAFFGS 161
Cdd:cd12082 81 AILLGLLLAALLLFFSPLILSLLGAEeevielaatyLTILILGLPITFL---GAVLSGILQGEGDTRTAMIISVLSNLLN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 162 AIFKILVIVNGGSYLY-----ICASVSLEALILAIGLSYFFSKKGVRDT----WKLNFTEAKRLLSQSWPLIISGVAFML 232
Cdd:cd12082 158 ILLDPLLIFGLGPPELgiagaALATVISYVIGALLLLIYLRKGKKILKFklslLKPDLELLRRLLRIGLPSAIQNSLLSL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 233 YMRIDQVMIGNMLNASAVGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKLR-EISIEKYHQRLQFLYDLLVVISVVIALFV 311
Cdd:cd12082 238 GLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLgAGNFDRARRITWVALLIGLLIGAVLGLLI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 312 TFLSDYIIDFFYT--KDYSDASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNIL-GLIIGVTLNYVLIPI-YGI 387
Cdd:cd12082 318 LLFPEPILSLFTNdpEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLsYWVVRLPLAYVLAYLgLGL 397
|
410
....*....|....*...
gi 1098933979 388 IGSVYATLVAYACAGYLF 405
Cdd:cd12082 398 YGIWLALVISLILAALVL 415
|
|
| MATE_MurJ_like |
cd13123 |
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
195-398 |
5.30e-04 |
|
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 42.05 E-value: 5.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 195 YFFSKKGVRDTWKLNFTEA--KRLLSQSWPLIISGVAFMLYMRIDQvMIGNMLNASAVGVYSVAVKMVEVWY-FFPIAIV 271
Cdd:cd13123 194 PALRRLGFRFRPRLDFRDPgvRRVLKLMLPALLGVSVSQINLLVDT-ILASFLPEGSISALYYADRLYQLPLgIFGVAIA 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 272 STLFPKIIKL-REISIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYTK---DYSDA---SIVIKLYSWVSVFY 344
Cdd:cd13123 273 TALLPRLSRLaAAGDLDEFRRTLSRGLRLVLFLLLPAAVGLIVLAEPIVRLLFERgafTAEDTlmtASALAAYALGLPAF 352
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1098933979 345 FLSSASGRWYineglqkYALNR-------NILGLIIGVTLNYVLIPIYGIIGSVYATLVAY 398
Cdd:cd13123 353 ALVKLLSRAF-------YALKDtktpvkiAVIAVAVNILLNLLLIKPLGHVGLALATSLSA 406
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
222-401 |
9.98e-04 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 41.34 E-value: 9.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 222 PLIISGVAFMLYMRIDQVMIGNMLNASAVGvysvAVKMVEVWYFFPIAI-------VSTLFPkiIKLREISIEKYHQRLQ 294
Cdd:cd13143 12 PAIIGMLVNGLYNIVDGIFVGHGVGALALA----AVNLVFPIIMLLMALglmigvgGASLIS--RRLGAGDREKANRIFS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 295 FLYDLLVVISVVIALFVTFLSDYIIDFF--------YTKDYsdasivIKLYSWVSVFYFLSSASGRWYINEGLQKYALNR 366
Cdd:cd13143 86 TALLLSLILGLLLTILGLLFLDPLLRLLgasgellpYAVDY------LRIILLGAPFTILSSVLNNLLRAEGKPKLAMLG 159
|
170 180 190
....*....|....*....|....*....|....*..
gi 1098933979 367 NILGLIIGVTLNYVLIPI--YGIIGSVYATLVAYACA 401
Cdd:cd13143 160 MLIGAVLNIILDPLFIFVlgLGIAGAALATVIAQLIS 196
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
222-436 |
1.59e-03 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 40.31 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 222 PLIISGVAFMLYMRIDQVMIGNMlnaSAVGVYSVAVKMVEVWYFFPIAIVSTLFPKIIKLREISIEKYHQ-RLQFLYDLL 300
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHL---GPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRlGRQAQQSLL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 301 V--VISVVIALFVTFLSDYIIDFFYTKDYSD--ASIVIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVT 376
Cdd:TIGR00797 78 LalLLGLPVLLVGYFFIDPLLSLMGADGEVAelAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINII 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1098933979 377 LNYVLI----PIYGIIGSVYATLVAYACA-------------GYLFDSLTHHTRISFIQKTKALWLPGNLMRLFFIF 436
Cdd:TIGR00797 158 LNYILIfgkfGFLGIVGAALATVISYWLMfllllyyikkakkIGLKWEGLLKPDWEVLKRLLKLGLPIAFRVILESL 234
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
333-404 |
2.79e-03 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 37.94 E-value: 2.79e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1098933979 333 VIKLYSWVSVFYFLSSASGRWYINEGLQKYALNRNILGLIIGVTLNYVLIPIYGIIGSVYATLVAYACAGYL 404
Cdd:pfam14667 1 VLQILALSIIFLSLSTVLTSILQGLGRTKLALIALLIGALVKLILNLLLIPLFGIVGAAIATVISLLVVALL 72
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
184-405 |
3.98e-03 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 39.36 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 184 LEALILAIGLSyffsKKGVRDTWKLNFT--EAKRLLSQSWPLIISGVAFMLYMRIDQvMIGNMLNASAVGVYSVAVKMVE 261
Cdd:COG0728 194 LQLLIQLPALR----RLGLRLRPRFDLRdpGVRRVLKLMLPALLGVSVSQINLLVDT-ILASFLPEGSVSALYYADRLYQ 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 262 VWY-FFPIAIVSTLFPKIIKL-REISIEKYHQRLQFLYDLLVVISVVIALFVTFLSDYIIDFFYTKDYSDA------SIV 333
Cdd:COG0728 269 LPLgLFGVAIGTALLPRLSRAaAAGDLEEFRRTLSRGLRLVLLLTLPAAVGLIVLAEPIVRLLFERGAFTAedtaltALA 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1098933979 334 IKLYSWVSVFYFLSSASGRWYineglqkYALNRN-------ILGLIIGVTLNYVLIPIYGIIGSVYAT-LVAYACAGYLF 405
Cdd:COG0728 349 LAAYALGLPAFALVKVLARAF-------YARQDTrtpvriaVIAVVVNIVLNLLLVPPLGHAGLALATsLSALVNALLLL 421
|
|
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