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Conserved domains on  [gi|1088626578|gb|OHE40825|]
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MAG: hypothetical protein A2013_02435 [Tenericutes bacterium GWE2_38_8]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
219-459 4.23e-49

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 167.22  E-value: 4.23e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 219 DASFFDWIlVIPVAWLMSFFGGILGNsFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPQSQ 298
Cdd:COG0706     2 DYGWFGFI-AKPLFWLLNFLHSLVGN-WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYK--DDPQKL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 299 QQMQMemmAIYKKHGINVM-GCLMPFLQMPIFIAMYGVVRrititggmYTENVANTNFLGINLANTQDGIIgIVLAGLVG 377
Cdd:COG0706    78 QQEMM---KLYKEEGVNPLgGCLPMLIQMPIFIALYRVLR--------NSIELRHAPFLGIPDLSAPDPYY-IFLPILMG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 378 ATMFILQKISMkkpsytkntakhnpnpqAAQTEKTMKFVSYFMVIMMAFASYQS-NALALYWIFGNIYSLGQTL-VNRKL 455
Cdd:COG0706   146 VTMFLQQKLNP-----------------APAQDPQQKKMMYIMPLMFLFFFLSFpAGLVLYWVVSNLLTIGQQLiINRRL 208

                  ....
gi 1088626578 456 NEKK 459
Cdd:COG0706   209 DKKK 212
Big_3 super family cl06524
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
137-208 3.35e-03

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


The actual alignment was detected with superfamily member pfam07523:

Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 36.12  E-value: 3.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1088626578 137 QIGESFDPTGIKIYAVQRDGDITVlngedvaeSFDDggYEPLGDDGFHNKYGYDVTYTHEGttVAKTFEVYV 208
Cdd:pfam07523   8 YVGDSWDAEDNFVSATYKDGDAEV--------PFDD--VEVSGTVDSTKAGEYTVTYTYKG--VSATFTVTV 67
 
Name Accession Description Interval E-value
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
219-459 4.23e-49

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 167.22  E-value: 4.23e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 219 DASFFDWIlVIPVAWLMSFFGGILGNsFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPQSQ 298
Cdd:COG0706     2 DYGWFGFI-AKPLFWLLNFLHSLVGN-WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYK--DDPQKL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 299 QQMQMemmAIYKKHGINVM-GCLMPFLQMPIFIAMYGVVRrititggmYTENVANTNFLGINLANTQDGIIgIVLAGLVG 377
Cdd:COG0706    78 QQEMM---KLYKEEGVNPLgGCLPMLIQMPIFIALYRVLR--------NSIELRHAPFLGIPDLSAPDPYY-IFLPILMG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 378 ATMFILQKISMkkpsytkntakhnpnpqAAQTEKTMKFVSYFMVIMMAFASYQS-NALALYWIFGNIYSLGQTL-VNRKL 455
Cdd:COG0706   146 VTMFLQQKLNP-----------------APAQDPQQKKMMYIMPLMFLFFFLSFpAGLVLYWVVSNLLTIGQQLiINRRL 208

                  ....
gi 1088626578 456 NEKK 459
Cdd:COG0706   209 DKKK 212
PRK01622 PRK01622
membrane protein insertase YidC;
206-458 2.02e-40

membrane protein insertase YidC;


Pssm-ID: 179310  Cd Length: 256  Bit Score: 145.66  E-value: 2.02e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 206 VYVAGGEKPITTGDAS---FFDWILVIPVAWLMSFFGGILGNSFALGILFTTIVVRTLAWPI----YAKSNDLSIKMNVA 278
Cdd:PRK01622   17 VLVLSGCSNAAPIDAHsdgFFDHYFVYPFSFLIQFVAHHIGGSYGIAIIIVTLIIRSLMIPLavsqYKSQRGMQEKMAVM 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 279 QPDMQRVQAKYATRKDPQSQQQMQMEMMAIYKKHGIN--VMGCLMPFLQMPIFIAMYGVVRRititggmyTENVANTNFL 356
Cdd:PRK01622   97 KPELDKIQAKLKVTKDLEKQKEYQKEMMELYKSGNINplAMGCLPLLIQMPILSAFYYAIRR--------TEEIASHSFL 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 357 GINLANTQdgiigIVLAGLVGATMFILQKISMKKPSytkntakhnpNPQAAQTEKTMKFvsyFMVIMMAFASYQS-NALA 435
Cdd:PRK01622  169 WFNLGHAD-----HILPIIAGLTYFIQMKVSQSNGT----------SPEQVQMLKIQGI---MMPAMILFMSFAApSALV 230
                         250       260
                  ....*....|....*....|...
gi 1088626578 436 LYWIFGNIYSLGQTLVNRKLNEK 458
Cdd:PRK01622  231 LYWITGGLFLMGQTIVLRKVMER 253
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
248-454 7.72e-40

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 141.36  E-value: 7.72e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 248 LGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPqsqQQMQMEMMAIYKKHGIN-VMGCLMPFLQM 326
Cdd:cd20070     2 LAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYK--DDK---QKLQQEMMKLYKEHGVNpLGGCLPLLIQM 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 327 PIFIAMYGVVRRititggmyTENVANTNFLGINLANTQDGIIGIvLAGLVGATMFILQKISMKKPSytkntakhnpnpqa 406
Cdd:cd20070    77 PIFIALYQVLRN--------SIELRGAPFLWWILDLSAPDPYYI-LPILMGVTMFLQQKLTPTPTD-------------- 133
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1088626578 407 aQTEKTMKFVSYFMVIMMAFASYQSNA-LALYWIFGNIYSLGQTLVNRK 454
Cdd:cd20070   134 -DQAPQQKMMMYFMPVMFTFIFLSFPSgLVLYWLVSNLFSIIQQLIINK 181
60KD_IMP pfam02096
60Kd inner membrane protein;
246-454 4.16e-38

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 137.22  E-value: 4.16e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 246 FALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPqsqQQMQMEMMAIYKKHGINVM-GCLMPFL 324
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYK--DDR---QKLQQEMMKLYKKEGVNPLgGCLPMLI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 325 QMPIFIAMYGVVRRITITGGmytenvANTNFLGINLANT--QDGIIGIVLAGLVGATMFILQKISMKkpsytkntakhnP 402
Cdd:pfam02096  76 QMPIFIALYRVLRNSIELRH------APFFLWIADLSAPdpISILHYYILPILMGVTMFLQQKLTPA------------P 137
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1088626578 403 NPQAAQTEKTMkfvSYFMVIMMAFASYQSNA-LALYWIFGNIYSLGQTLVNRK 454
Cdd:pfam02096 138 QDQPPQMKMMM---LYFMPLMFLFFFLNFPAgLVLYWVVSNLLSIGQQLIINR 187
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
245-451 2.74e-37

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 134.53  E-value: 2.74e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 245 SFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPqsqQQMQMEMMAIYKKHGIN-VMGCLMPF 323
Cdd:TIGR03592   1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYK--EDP---QKLQQEMMKLYKEEGVNpLGGCLPLL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 324 LQMPIFIAMYGVVRRititggmyTENVANTNFLGI-NLAnTQDGIigIVLAGLVGATMFILQKISMKKPSytkntakhnp 402
Cdd:TIGR03592  76 IQMPIFIALYQVLLR--------SIELRHAPFLWIiDLS-SPDPY--YILPILMGVTMFLQQKLSPKGPP---------- 134
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1088626578 403 npqaaqTEKTMKFVSYFMVIMMAFASYQ-SNALALYWIFGNIYSLGQTLV 451
Cdd:TIGR03592 135 ------DPAQQKMMMYFMPLMFLFFFLSfPAGLVLYWVVSNLFTIIQQLI 178
Big_3 pfam07523
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
137-208 3.35e-03

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 36.12  E-value: 3.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1088626578 137 QIGESFDPTGIKIYAVQRDGDITVlngedvaeSFDDggYEPLGDDGFHNKYGYDVTYTHEGttVAKTFEVYV 208
Cdd:pfam07523   8 YVGDSWDAEDNFVSATYKDGDAEV--------PFDD--VEVSGTVDSTKAGEYTVTYTYKG--VSATFTVTV 67
 
Name Accession Description Interval E-value
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
219-459 4.23e-49

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 167.22  E-value: 4.23e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 219 DASFFDWIlVIPVAWLMSFFGGILGNsFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPQSQ 298
Cdd:COG0706     2 DYGWFGFI-AKPLFWLLNFLHSLVGN-WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYK--DDPQKL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 299 QQMQMemmAIYKKHGINVM-GCLMPFLQMPIFIAMYGVVRrititggmYTENVANTNFLGINLANTQDGIIgIVLAGLVG 377
Cdd:COG0706    78 QQEMM---KLYKEEGVNPLgGCLPMLIQMPIFIALYRVLR--------NSIELRHAPFLGIPDLSAPDPYY-IFLPILMG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 378 ATMFILQKISMkkpsytkntakhnpnpqAAQTEKTMKFVSYFMVIMMAFASYQS-NALALYWIFGNIYSLGQTL-VNRKL 455
Cdd:COG0706   146 VTMFLQQKLNP-----------------APAQDPQQKKMMYIMPLMFLFFFLSFpAGLVLYWVVSNLLTIGQQLiINRRL 208

                  ....
gi 1088626578 456 NEKK 459
Cdd:COG0706   209 DKKK 212
PRK01622 PRK01622
membrane protein insertase YidC;
206-458 2.02e-40

membrane protein insertase YidC;


Pssm-ID: 179310  Cd Length: 256  Bit Score: 145.66  E-value: 2.02e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 206 VYVAGGEKPITTGDAS---FFDWILVIPVAWLMSFFGGILGNSFALGILFTTIVVRTLAWPI----YAKSNDLSIKMNVA 278
Cdd:PRK01622   17 VLVLSGCSNAAPIDAHsdgFFDHYFVYPFSFLIQFVAHHIGGSYGIAIIIVTLIIRSLMIPLavsqYKSQRGMQEKMAVM 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 279 QPDMQRVQAKYATRKDPQSQQQMQMEMMAIYKKHGIN--VMGCLMPFLQMPIFIAMYGVVRRititggmyTENVANTNFL 356
Cdd:PRK01622   97 KPELDKIQAKLKVTKDLEKQKEYQKEMMELYKSGNINplAMGCLPLLIQMPILSAFYYAIRR--------TEEIASHSFL 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 357 GINLANTQdgiigIVLAGLVGATMFILQKISMKKPSytkntakhnpNPQAAQTEKTMKFvsyFMVIMMAFASYQS-NALA 435
Cdd:PRK01622  169 WFNLGHAD-----HILPIIAGLTYFIQMKVSQSNGT----------SPEQVQMLKIQGI---MMPAMILFMSFAApSALV 230
                         250       260
                  ....*....|....*....|...
gi 1088626578 436 LYWIFGNIYSLGQTLVNRKLNEK 458
Cdd:PRK01622  231 LYWITGGLFLMGQTIVLRKVMER 253
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
248-454 7.72e-40

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 141.36  E-value: 7.72e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 248 LGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPqsqQQMQMEMMAIYKKHGIN-VMGCLMPFLQM 326
Cdd:cd20070     2 LAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYK--DDK---QKLQQEMMKLYKEHGVNpLGGCLPLLIQM 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 327 PIFIAMYGVVRRititggmyTENVANTNFLGINLANTQDGIIGIvLAGLVGATMFILQKISMKKPSytkntakhnpnpqa 406
Cdd:cd20070    77 PIFIALYQVLRN--------SIELRGAPFLWWILDLSAPDPYYI-LPILMGVTMFLQQKLTPTPTD-------------- 133
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1088626578 407 aQTEKTMKFVSYFMVIMMAFASYQSNA-LALYWIFGNIYSLGQTLVNRK 454
Cdd:cd20070   134 -DQAPQQKMMMYFMPVMFTFIFLSFPSgLVLYWLVSNLFSIIQQLIINK 181
60KD_IMP pfam02096
60Kd inner membrane protein;
246-454 4.16e-38

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 137.22  E-value: 4.16e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 246 FALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPqsqQQMQMEMMAIYKKHGINVM-GCLMPFL 324
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYK--DDR---QKLQQEMMKLYKKEGVNPLgGCLPMLI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 325 QMPIFIAMYGVVRRITITGGmytenvANTNFLGINLANT--QDGIIGIVLAGLVGATMFILQKISMKkpsytkntakhnP 402
Cdd:pfam02096  76 QMPIFIALYRVLRNSIELRH------APFFLWIADLSAPdpISILHYYILPILMGVTMFLQQKLTPA------------P 137
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1088626578 403 NPQAAQTEKTMkfvSYFMVIMMAFASYQSNA-LALYWIFGNIYSLGQTLVNRK 454
Cdd:pfam02096 138 QDQPPQMKMMM---LYFMPLMFLFFFLNFPAgLVLYWVVSNLLSIGQQLIINR 187
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
245-451 2.74e-37

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 134.53  E-value: 2.74e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 245 SFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPqsqQQMQMEMMAIYKKHGIN-VMGCLMPF 323
Cdd:TIGR03592   1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYK--EDP---QKLQQEMMKLYKEEGVNpLGGCLPLL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 324 LQMPIFIAMYGVVRRititggmyTENVANTNFLGI-NLAnTQDGIigIVLAGLVGATMFILQKISMKKPSytkntakhnp 402
Cdd:TIGR03592  76 IQMPIFIALYQVLLR--------SIELRHAPFLWIiDLS-SPDPY--YILPILMGVTMFLQQKLSPKGPP---------- 134
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1088626578 403 npqaaqTEKTMKFVSYFMVIMMAFASYQ-SNALALYWIFGNIYSLGQTLV 451
Cdd:TIGR03592 135 ------DPAQQKMMMYFMPLMFLFFFLSfPAGLVLYWVVSNLFTIIQQLI 178
PRK02944 PRK02944
YidC family membrane integrase SpoIIIJ;
213-451 9.19e-33

YidC family membrane integrase SpoIIIJ;


Pssm-ID: 179508  Cd Length: 255  Bit Score: 124.88  E-value: 9.19e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 213 KPITTGDASFFDWILVIPVAWLMSFFGGILGNSFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYATr 292
Cdd:PRK02944   26 QPITPKSTGFWNEYFVYPLSQLITYFANLFGSNYGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYSS- 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 293 KDPQSQQQMQMEMMAIYKKHGINVM-GCLMPFLQMPIFIAMYGVVrrititggMYTENVANTNFLGINLANTQDGIIGIV 371
Cdd:PRK02944  105 KDQATQQKLQQEMMQLFQKNGVNPLaGCLPIFIQMPILIAFYHAI--------MRTSEISKHSFLWFDLGQADPYYILPI 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 372 LAGLvgaTMFILQKISMkkpsytKNTAKHNPNpqaaqtektMKFVSYFMVIM-MAFASYQSNALALYWIFGNIYSLGQTL 450
Cdd:PRK02944  177 VAGI---TTFIQQKLMM------AGTAGQNPQ---------MAMMLWLMPIMiLIFAINFPAALSLYWVVGNIFMIAQTY 238

                  .
gi 1088626578 451 V 451
Cdd:PRK02944  239 L 239
PRK01318 PRK01318
membrane protein insertase; Provisional
225-467 1.04e-28

membrane protein insertase; Provisional


Pssm-ID: 234942 [Multi-domain]  Cd Length: 521  Bit Score: 118.44  E-value: 1.04e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 225 WILVIPVAWLMSFFGGILGNsFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDPQSQQQMQMe 304
Cdd:PRK01318  303 WFITKPLFWLLDFLHSFVGN-WGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYK--DDPQKMQQEMM- 378
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 305 mmAIYKKHGINVM-GCLMPFLQMPIFIAMYGVVrrititggmyteNVA----NTNFLG-IN-LAnTQDG--IIGI-VLAG 374
Cdd:PRK01318  379 --ELYKKEKVNPLgGCLPILIQIPIFFALYKVL------------LVSielrHAPFIGwIHdLS-APDPyfILHIgLLPI 443
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 375 LVGATMFILQKIsmkkpsytkntakhNPNPQAAQTEKTMKFVSY-FMVIMMAFASyqsnALALYWIFGNIYSLGQTLVNR 453
Cdd:PRK01318  444 LMGITMFLQQKL--------------NPTPTDPMQAKIMKFMPLiFTFFFLSFPA----GLVLYWIVNNLLTIIQQYLIN 505
                         250
                  ....*....|....
gi 1088626578 454 KLNEKKHEHLMQKQ 467
Cdd:PRK01318  506 RRLEKKKLLAANKK 519
PRK00145 PRK00145
putative inner membrane protein translocase component YidC; Provisional
243-461 3.57e-27

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234665 [Multi-domain]  Cd Length: 223  Bit Score: 108.67  E-value: 3.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 243 GNSFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYatRKDPQSQQQMQMEmmaIYKKHGINVM-GCLM 321
Cdd:PRK00145   28 NFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKY--KNDPQKLQQEMMK---LYKEKGVNPLgGCLP 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 322 PFLQMPIFIAMYGVVRRITitggmyteNVANTNFLGI-NLANTQdgiIGIVLAGLVGATMFIlqkismkkPSYTKNTAKh 400
Cdd:PRK00145  103 LLIQWPILIALYYVFNNLT--------GINGVSFLWIkDLAKPD---ITWILPILSGATTYL--------SGYLMTKAD- 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1088626578 401 npNPQAAQTeKTMkfvSYFMVIMMAFASYQ-SNALALYWIFGNIYSLGQTLVNRKLNEKKHE 461
Cdd:PRK00145  163 --SSQAGQM-KTM---NIGMSIFMGVMSWKfKSALVLYWVIGNLIQIIQTYFIKKLELKKKV 218
PRK02463 PRK02463
OxaA-like protein precursor; Provisional
217-451 2.45e-25

OxaA-like protein precursor; Provisional


Pssm-ID: 235040  Cd Length: 307  Bit Score: 105.58  E-value: 2.45e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 217 TGDASFFDW-ILVIPVAWLMSFFGGILGNSFALGILFTTIVVRTLAWP--IYA--KSNDLSIKMNVAQPDMQRVQAKYAT 291
Cdd:PRK02463   30 HGNPTGFIWnFLGAPMSYFIDYFANNLGLGFGLAIIIVTIIVRLIILPlgLYQswKATYQSEKMAYLKPVFEPINERLKN 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 292 RKDPQSQQQMQMEMMAIYKKHGINV---MGCLMPFLQMPIFIAMYGVVRrititggmYTENVANTNFLGINLantqdGII 368
Cdd:PRK02463  110 ATTQEEKMAAQTELMAAQRENGISMlggIGCLPLLIQMPFFSALYFAAQ--------YTKGVSTSTFLGIDL-----GSP 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 369 GIVLAGLVGATMFILQKISMKKPsytkntakhnPNPQAAQTEKTMkfvsYFMVIMMAFASYQSNA-LALYWIFGNIYSLG 447
Cdd:PRK02463  177 SLVLTAIIGVLYFFQSWLSMMGV----------PEEQREQMKAMM----YMMPIMMVVFSFSSPAgVGLYWLVGGFFSII 242

                  ....
gi 1088626578 448 QTLV 451
Cdd:PRK02463  243 QQLI 246
5TM_Oxa1-like cd20069
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ...
250-451 2.58e-21

Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410993 [Multi-domain]  Cd Length: 201  Bit Score: 91.43  E-value: 2.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 250 ILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYATRK---DPQSQQQMQMEMMAIYKKHGIN-VMGCLMPFLQ 325
Cdd:cd20069     8 IAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKLKEARasgDQLEAAEARKELKELMKKHNVNpLKSLLLPLVQ 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 326 MPIFIAMYGVVRRITI-------TGGMY--TenvantnflgiNLAnTQDGiiGIVLAGLVGATMFILQKISMKKPSytkn 396
Cdd:cd20069    88 APVFISFFFALRKMANlpvpsfkTGGLLwfT-----------DLT-VPDP--YYILPILTSLTFLATIELGAETGT---- 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1088626578 397 takhnpnpQAAQTEKTMKFVSYFM-VIMMAFASYQSNALALYWIFGNIYSLGQTLV 451
Cdd:cd20069   150 --------SGSPQSKTMKNVFRGLpVLMIPFTANFPSAVFLYWITSNLFSLAQNLL 197
PRK01315 PRK01315
putative inner membrane protein translocase component YidC; Provisional
220-451 1.48e-19

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234941  Cd Length: 329  Bit Score: 89.41  E-value: 1.48e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 220 ASFFDWILViPVAWLMS------------FFGGILGNSFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQA 287
Cdd:PRK01315    5 ADFGSAIMT-PLYWVISgilvlfhtllgfLFGPDSGLTWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 288 KYATRKDpqsqqQMQMEMMAIYKKHGIN-VMGCLMPFLQMPIFIAMYGVV-----RRIT---ITGGMyTENVANTNFLGI 358
Cdd:PRK01315   84 KYKGDRE-----RMSQEMMKLYKETGTNpLSSCLPLLLQMPIFFALYRVLdsaasRGDGigpINPPL-LESFRHAHIFGA 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 359 NLA-----NTQDG-----IIGIVLAGLVGATMFILQKISMkkpsyTKNTAKHNPNPQAAQTEKTMKFVSYFMVIMMAFAS 428
Cdd:PRK01315  158 PLAatflqALNAGntavqVVAAVLIILMSASQFITQLQLM-----TKNMPPEAKTGPMAQQQKMLLYLFPLMFLVSGIAF 232
                         250       260
                  ....*....|....*....|...
gi 1088626578 429 yqSNALALYWIFGNIYSLGQTLV 451
Cdd:PRK01315  233 --PVGVLFYWLTSNVWTMGQQFY 253
5TM_YidC_Oxa1_Alb3 cd19751
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ...
248-451 5.35e-19

Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410992 [Multi-domain]  Cd Length: 189  Bit Score: 84.53  E-value: 5.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 248 LGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYATRK-DPQSQQQMQMEMMAIYKKHGINVM-GCLMPFLQ 325
Cdd:cd19751     2 LSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKAsKDKVQQEMQKEMLGLYKKHGVNPMaGCLPLFIQ 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 326 MPIFIAMYGVVRRititggmyTENVANTNFLGINLANTQDGIigIVLAGLVGATMFILQKISMkkpsytknTAKHNPNPQ 405
Cdd:cd19751    82 LPIFMAFYFAIMR--------TEEIRYHTFLWFFDLGQPDYL--YILPFVAGITTYFQFKMTM--------SHQQQMQMM 143
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1088626578 406 AAQTEKTMKFVSYFMVIM-MAFASyqsnALALYWIFGNIYSLGQTLV 451
Cdd:cd19751   144 QMQMKVMLYVMPVMIIIAgLSFPS----ALSLYWIISNLFMIIQTYF 186
PRK03449 PRK03449
putative inner membrane protein translocase component YidC; Provisional
230-466 1.66e-17

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 179580  Cd Length: 304  Bit Score: 82.81  E-value: 1.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 230 PVAWLMSF----FGGILGNS----FALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAtrKDpqsQQQM 301
Cdd:PRK03449    8 PVSAILWFwhklFSFVLGPDngfaWALSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYG--ND---RQKM 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 302 QMEMMAIYKKHGIN-VMGCLMPFLQMPIFIAMYGVVRRITITG------GMYTENVANT-----------NFLGINL--- 360
Cdd:PRK03449   83 ALEMQKLQKEHGFNpILGCLPMLAQIPVFLGLFHVLRSFNRTGtgfgqlGMSVEENRNTpnyvfsaedvqSFLDARLfga 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 361 --------------ANTQDGIIGIVlagLVGATMFILQKISM---KKPSYTKNTAKHNPNPQAAQTEKTMKFVSYFMVIM 423
Cdd:PRK03449  163 plsayitmprsgldAFVDFTRTNII---LVGVPLMIIAGVAThfnSRASVARQSAEAAANPQTAMMNKLALWVFPLGVLV 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1088626578 424 MAFasYQSNALALYWIFGNIYSLGQT-LVNRKLN----EKKHEHLMQK 466
Cdd:PRK03449  240 GGP--FLPLAILLYWVSNNIWTFGQQhYVFGKIDkeeeAKKQAKAERR 285
PRK02201 PRK02201
putative inner membrane protein translocase component YidC; Provisional
185-450 1.05e-16

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 235012  Cd Length: 357  Bit Score: 81.21  E-value: 1.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 185 NKYGYDVTYTHEGTTVAKTfevyvaggekPITTGDASFFDWIlVIPVAWLMSFF------GGILGNSFALGILFTTIVVR 258
Cdd:PRK02201   77 NNYRYLFISSNTGPYNPIT----------SWTWKYGPFYGLF-VYPIAQIILSImasqslSELYGWSTILAIIVVVLIIR 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 259 TLAWPIYAKSNDLSIKMNVAQPDMQRVQAKYAT-RKDPQSQQQMQMEMMAIYKKHGINVMGCLMP-FLQMPIFIAMYGVV 336
Cdd:PRK02201  146 LISFLITFKSTFNQEKQEELQGKKAKIDAKYKDyKKDKQMKQRKQQEIQELYKKHNISPFSPFVQmFVTLPIFIAVYRVV 225
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 337 RRititggmyTENVANTNFLGINLANT----------QDGIIGIVLAGLVGATMFILQKISMKKPSYTKNTAKhnpnpQA 406
Cdd:PRK02201  226 QS--------LPSIKVTTWLGIDLSATswqeifagnwIYLPILIIVVPVQALSQLLPQILNKKKNKERTLNVK-----EK 292
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1088626578 407 AQTEKTMKFVSYFMVIMMAFASYQSNALALYWIFGNIYSLGQTL 450
Cdd:PRK02201  293 EALKKQNKTQNIISIVFIFFGVIFAAGVQIYWIIGGIWTILQTL 336
PRK01001 PRK01001
putative inner membrane protein translocase component YidC; Provisional
211-467 7.26e-12

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234887 [Multi-domain]  Cd Length: 795  Bit Score: 67.90  E-value: 7.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 211 GEKPITTGDASFFDWILVI--PVAWL----MSFFGgILGNSFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQR 284
Cdd:PRK01001  536 GENPEYLDSITFRGFFSFItePFAALlfiiMKFFK-FLTGSWGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQE 614
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 285 VQAKYatRKDPQSQQQMQMemmAIYKKHGIN-VMGCLMPFLQMPIFIAMYGVVRRITITGGM-----YTENVANTNFL-- 356
Cdd:PRK01001  615 IQQKY--KKEPKRAQMEIM---ALYKTNKVNpITGCLPLLIQLPFLIAMFDLLKSSFLLRGAsfipgWIDNLTAPDVLfs 689
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 357 ---GINLANTQDGIIGIvlagLVGATMFILQKISMKKPSytkntakhNPNPQAAQTEKTMkfvSYFMVIMMAFASYQ-SN 432
Cdd:PRK01001  690 wetPIWFIGNEFHLLPI----LLGVVMFAQQKISSLKRK--------GPVTDQQRQQEAM---GTMMALLFTFMFYNfPS 754
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1088626578 433 ALALYWIFGNIYSLGQT-LVNRKLNEK--KHEHLMQKQ 467
Cdd:PRK01001  755 GLNIYWLSSMLLGVIQQwVTNKILDSKhlKNEVVPNKK 792
PRK02654 PRK02654
putative inner membrane protein translocase component YidC; Provisional
227-337 2.68e-09

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 235058  Cd Length: 375  Bit Score: 58.84  E-value: 2.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 227 LVIPVawlMSFFGGILgNSFALGILFTTIVVRTLAWPIYAKSNDLSIKMNVAQPDMQR----VQAKYAtrKDPQSQQQMQ 302
Cdd:PRK02654   12 VMLPI---LDFFYGIV-PSYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYK--NDPQKQQEEM 85
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1088626578 303 MEmmaIYKKHGINVMGCLMPFLQMPIFIAMYGVVR 337
Cdd:PRK02654   86 GK---LMKEFGNPLAGCLPLLVQMPILFALFATLR 117
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
232-460 1.01e-08

putative inner membrane protein translocase component YidC; Validated


Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 57.17  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 232 AWLMSFFGgilgnsfalgiLFTTI--VVRTLAWPIYaKSNDLSIKMnvaQPDMQRVQAKYATRKDPQSQQQMQMEMMAIY 309
Cdd:PRK00247   31 AWFASLFG-----------LVITVraIIAPFTWQQY-KSGRTAAHI---RPKRKALREEYKGKTDEASIRELQQKQKDLN 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 310 KKHGINVM-GCLMPFLQMPIFIAMYGVVRRIT-ITGGMYTENVANTNFLGIN---------------------------- 359
Cdd:PRK00247   96 KEYGYNPLaGCVPALIQIPVFLGLYQVLLRMArPEGGLENPVHQPIGFLTSEevesflqgrvfnvplpayvsmpaeqlay 175
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088626578 360 LANTQDGIIGIVLAGLVGATMFILqkISMKKPSYTKNTAKHNPNPQAAQTEK---TMKFVSYFMVIMMAFASYQSNALAL 436
Cdd:PRK00247  176 LGTTQATVLAFVLPLFIAAAVFTA--INMAMSTYRSFQTNDHDSGFAVGMLKfliVMAILAPIFPLSLGLTGPFPTAIAL 253
                         250       260
                  ....*....|....*....|....
gi 1088626578 437 YWIFGNIYSLGQTLVNRKLNEKKH 460
Cdd:PRK00247  254 YWVANNLWTLIQNIIMYLILERKY 277
Big_3 pfam07523
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
137-208 3.35e-03

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 36.12  E-value: 3.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1088626578 137 QIGESFDPTGIKIYAVQRDGDITVlngedvaeSFDDggYEPLGDDGFHNKYGYDVTYTHEGttVAKTFEVYV 208
Cdd:pfam07523   8 YVGDSWDAEDNFVSATYKDGDAEV--------PFDD--VEVSGTVDSTKAGEYTVTYTYKG--VSATFTVTV 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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