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Conserved domains on  [gi|1088279055|gb|OHB34133|]
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MAG: phosphoenolpyruvate--protein phosphotransferase [Desulfuromonadaceae bacterium GWC2_58_13]

Protein Classification

phosphoenolpyruvate--protein phosphotransferase( domain architecture ID 18715421)

phosphoenolpyruvate--protein phosphotransferase transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein

CATH:  1.10.274.10
EC:  2.7.3.9

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 209-777 0e+00

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


:

Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 743.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 209 LRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILE 288
Cdd:COG1080     1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 289 DRSFMEKLRAEIHLGH-GVSFALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNHQATL-QLKCPGILIAR 366
Cdd:COG1080    81 DPELIEEVEELIREGRyNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLsDLPEPVILVAH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 367 EILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRR 446
Cdd:COG1080   161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNPDEETLAEYRE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 447 LEADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVI 526
Cdd:COG1080   241 RQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYRAVA 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 527 ENFPDYPVTIRSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRA 606
Cdd:COG1080   321 EAMGGRPVTIRTLDIGGDKPLPYLPLPKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAHGNLRIMFPMISSVEELRQ 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 607 CKEVIEEARANLIRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAI 686
Cdd:COG1080   401 AKALLEEAKAELRAEGIPFDEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLHPAV 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 687 LKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMTDSASI 766
Cdd:COG1080   481 LRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALALDTAEEV 560

                         570
                  ....*....|.
gi 1088279055 767 RGHLVKVLKEI 777
Cdd:COG1080   561 RALLEEFLAEL 571
PtsP COG3605
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];
11-184 3.14e-58

Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];


:

Pssm-ID: 442824 [Multi-domain]  Cd Length: 188  Bit Score: 196.27  E-value: 3.14e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKR 90
Cdd:COG3605     4 KALRRISEAVASALDLDEALDRIVRRIAEALGVDVCSIYLLDPDGGRLELRATEGLNPEAVGKVRLPLGEGLVGLVAERG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  91 QVVAIQEPEKHPRYRYFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLES 170
Cdd:COG3605    84 EPLNLADAASHPRFKYFPETGEEGFRSFLGVPIIRRGRVLGVLVVQSREPREFTEEEVEFLVTLAAQLAEAIANAELLGE 163

                         170
                  ....*....|....
gi 1088279055 171 IRKNEEEKSVFARE 184
Cdd:COG3605   164 LRAALAELSLAREE 177
 
Name Accession Description Interval E-value
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 209-777 0e+00

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 743.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 209 LRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILE 288
Cdd:COG1080     1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 289 DRSFMEKLRAEIHLGH-GVSFALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNHQATL-QLKCPGILIAR 366
Cdd:COG1080    81 DPELIEEVEELIREGRyNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLsDLPEPVILVAH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 367 EILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRR 446
Cdd:COG1080   161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNPDEETLAEYRE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 447 LEADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVI 526
Cdd:COG1080   241 RQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYRAVA 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 527 ENFPDYPVTIRSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRA 606
Cdd:COG1080   321 EAMGGRPVTIRTLDIGGDKPLPYLPLPKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAHGNLRIMFPMISSVEELRQ 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 607 CKEVIEEARANLIRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAI 686
Cdd:COG1080   401 AKALLEEAKAELRAEGIPFDEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLHPAV 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 687 LKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMTDSASI 766
Cdd:COG1080   481 LRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALALDTAEEV 560

                         570
                  ....*....|.
gi 1088279055 767 RGHLVKVLKEI 777
Cdd:COG1080   561 RALLEEFLAEL 571
PRK11061 PRK11061
phosphoenolpyruvate--protein phosphotransferase;
11-771 0e+00

phosphoenolpyruvate--protein phosphotransferase;


Pssm-ID: 182937 [Multi-domain]  Cd Length: 748  Bit Score: 559.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLsRKAVGK-VTMKIGEGLTGLAAEK 89
Cdd:PRK11061    3 TRLREIVEKVASAPRLNEALDILVTETCLAMDTEVCSVYLADHDRRCYYLMATRGL-KKPRGRtVTLAFDEGIVGLVGRL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  90 RQVVAIQEPEKHPRYRYFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLE 169
Cdd:PRK11061   82 AEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIYRRQLLGVLVVQQRELRQFDESEESFLVTLATQLAAILSQSQLTA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 170 SirkneeeksvFARElektRQTlldkdkeratreprssALRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQK 249
Cdd:PRK11061  162 L----------FGQY----RQT----------------RIRALPASPGVAIAEGWQDATQPLLEQVYPASTLDPALERER 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 250 LDLTLEKTRIQTLFLEKRVAERLSQNDAAIF--HSHLmiLEDRSFMEKLRAEIHLGHGVSFALKKIVAEYIEVFERMDDP 327
Cdd:PRK11061  212 LTGALEEAANEFRRYSKRFAAGAQKETAAIFdlYSHL--LNDPRLRRELFAEVDKGSVAEWAVKQVIEKFAEQFAALSDN 289

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 328 YLRERAADIKDIGRRLLANLNDNHQATLQLKCPGILIAREILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPAL 407
Cdd:PRK11061  290 YLRERAGDLRALGQRLLFHLDDSEQGPNAWPERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTV 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 408 VGVKgavkaTTPE----CRVILDANSGCLYIDPAPHVTEEYRRLeADASRELHRLDEFR-NLPPVTSDGQKITLRANIGL 482
Cdd:PRK11061  370 MGAD-----IQPSllhqRLLIVDGYRGELLVDPEPVLLQEYQRL-ISEEIELSRLAEDDvNLPAQLKSGERIKVMLNAGL 443

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 483 VSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVIENFPDYPVTIRSLDIGGDKALPYFsPPKEDNPFMGW 562
Cdd:PRK11061  444 SAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFPDKPVTLRTLDIGADKQLPYM-PISEENPCLGW 522

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 563 RSVRVSLDNRDIFRTQIEAIMMAGA-HGPVKLLFPMISGLEEVRACKEVIEEARANlIRENIPFAQSMP-IGVMIEVPSA 640
Cdd:PRK11061  523 RGIRITLDQPEIFLIQVRAMLRANAaTGNLSILLPMVTSIDEVDEARRLIDRAGRE-VEEMLGYEIPKPrIGIMIEVPSM 601

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 641 VMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAILKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVL 720
Cdd:PRK11061  602 VFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLL 681

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1088279055 721 YGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMTDSASIRgHLV 771
Cdd:PRK11061  682 IGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQRSLEAQLATEVR-HQV 731
PTS_I_fam TIGR01417
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ...
 209-761 4.90e-156

phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.


Pssm-ID: 273611 [Multi-domain]  Cd Length: 565  Bit Score: 465.81  E-value: 4.90e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 209 LRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILE 288
Cdd:TIGR01417   1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 289 DRSFMEKLRAEIHLGH-GVSFALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNHQATL-QLKCPGILIAR 366
Cdd:TIGR01417  81 DPELTEEVIELIKKDHkNAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDLsEIQDEVILVAE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 367 EILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRR 446
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 447 LEADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVI 526
Cdd:TIGR01417 241 KQEAVSSEKAELAKLKDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAYKTVL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 527 ENFPDYPVTIRSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRA 606
Cdd:TIGR01417 321 EAMESDAVIVRTLDIGGDKELPYLNFPKEENPFLGYRAIRLALEREEILRTQLRAILRASAYGKLRIMFPMVATVEEIRA 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 607 CKEVIEEARANLIRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAI 686
Cdd:TIGR01417 401 VKQELEEEKQELNDEGKAFDENIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPYNPAV 480

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1088279055 687 LKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMT 761
Cdd:TIGR01417 481 LRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQP 555
PEP-utilizers_C pfam02896
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ...
 457-743 4.08e-120

PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.


Pssm-ID: 397163 [Multi-domain]  Cd Length: 292  Bit Score: 363.17  E-value: 4.08e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 457 RLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVIENFPDYPVTI 536
Cdd:pfam02896   3 ELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVTV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 537 RSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRACKEVIEEARA 616
Cdd:pfam02896  83 RTLDIGGDKELPYLEEPEEMNPFLGWRGIRIGLDRPELFRTQLRAILRASAFGNLRIMFPMVASVEELREAKAIIEEVKE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 617 NLiRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAILKVLNFVAKT 696
Cdd:pfam02896 163 EL-DAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIRA 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1088279055 697 ARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLR 743
Cdd:pfam02896 242 AHRHGKWVGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLA 288
PtsP COG3605
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];
11-184 3.14e-58

Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];


Pssm-ID: 442824 [Multi-domain]  Cd Length: 188  Bit Score: 196.27  E-value: 3.14e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKR 90
Cdd:COG3605     4 KALRRISEAVASALDLDEALDRIVRRIAEALGVDVCSIYLLDPDGGRLELRATEGLNPEAVGKVRLPLGEGLVGLVAERG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  91 QVVAIQEPEKHPRYRYFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLES 170
Cdd:COG3605    84 EPLNLADAASHPRFKYFPETGEEGFRSFLGVPIIRRGRVLGVLVVQSREPREFTEEEVEFLVTLAAQLAEAIANAELLGE 163

                         170
                  ....*....|....
gi 1088279055 171 IRKNEEEKSVFARE 184
Cdd:COG3605   164 LRAALAELSLAREE 177
GAF smart00065
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ...
 25-172 2.83e-21

Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.


Pssm-ID: 214500 [Multi-domain]  Cd Length: 149  Bit Score: 90.90  E-value: 2.83e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055   25 DLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKRQVVAIQEPEKHPRY 104
Cdd:smart00065   1 DLEELLQTILEELRQLLGADRVLIYLVDENDRGELVLVAADGLTLPTLGIRFPLDEGLAGRVAETGRPLNIPDVEADPLF 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1088279055  105 RYFKETGEERFHSFLGLPLFDRKTPIGVLTI-QTKEPRKFSAEDISALSTIAFQASSIVINARLLESIR 172
Cdd:smart00065  81 AEDLLGRYQGVRSFLAVPLVADGELVGVLALhNKKSPRPFTEEDEELLQALANQLAIALANAQLYEELR 149
GAF_2 pfam13185
GAF domain; The GAF domain is named after some of the proteins it is found in, including ...
 23-162 4.06e-16

GAF domain; The GAF domain is named after some of the proteins it is found in, including cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. It is also found in guanylyl cyclases and phytochromes. The structure of a GAF domain shows that the domain shares a similar fold with the PAS domain. This domain can bind O2, CO and NO (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 433019 [Multi-domain]  Cd Length: 137  Bit Score: 75.58  E-value: 4.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  23 SHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQetlRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKRQVVAIQEPEKHP 102
Cdd:pfam13185   1 AADLEELLDAVLEAAVELGASAVGFILLVDDDG---RLAAWGGAADELSAALDDPPGEGLVGEALRTGRPVIVNDLAADP 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 103 RYRYFKEtGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIV 162
Cdd:pfam13185  78 AKKGLPA-GHAGLRSFLSVPLVSGGRVVGVLALGSNRPGAFDEEDLELLELLAEQAAIAI 136
PRK05022 PRK05022
nitric oxide reductase transcriptional regulator NorR;
116-180 2.43e-04

nitric oxide reductase transcriptional regulator NorR;


Pssm-ID: 235331 [Multi-domain]  Cd Length: 509  Bit Score: 44.39  E-value: 2.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1088279055 116 HSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLESIRK-NEEEKSV 180
Cdd:PRK05022  110 HDCMGLPLFVDGRLIGALTLDALDPGQFDAFSDEELRALAALAAATLRNALLIEQLESqAELPQDV 175
 
Name Accession Description Interval E-value
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 209-777 0e+00

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 743.05  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 209 LRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILE 288
Cdd:COG1080     1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 289 DRSFMEKLRAEIHLGH-GVSFALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNHQATL-QLKCPGILIAR 366
Cdd:COG1080    81 DPELIEEVEELIREGRyNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLsDLPEPVILVAH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 367 EILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRR 446
Cdd:COG1080   161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNPDEETLAEYRE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 447 LEADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVI 526
Cdd:COG1080   241 RQAEYAAERAELARLRDLPAVTLDGVRVELAANIGLPEDAAAALENGAEGVGLFRTEFLFMDRDDLPTEEEQFEAYRAVA 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 527 ENFPDYPVTIRSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRA 606
Cdd:COG1080   321 EAMGGRPVTIRTLDIGGDKPLPYLPLPKEENPFLGLRAIRLCLDRPELFRTQLRAILRASAHGNLRIMFPMISSVEELRQ 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 607 CKEVIEEARANLIRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAI 686
Cdd:COG1080   401 AKALLEEAKAELRAEGIPFDEDIPVGIMIEVPAAALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLHPAV 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 687 LKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMTDSASI 766
Cdd:COG1080   481 LRLIKMVIDAAHKAGKPVGVCGEMAGDPLATPLLLGLGLDELSMSPSSIPAVKAIIRRLDLAEARALAEKALALDTAEEV 560

                         570
                  ....*....|.
gi 1088279055 767 RGHLVKVLKEI 777
Cdd:COG1080   561 RALLEEFLAEL 571
PRK11061 PRK11061
phosphoenolpyruvate--protein phosphotransferase;
11-771 0e+00

phosphoenolpyruvate--protein phosphotransferase;


Pssm-ID: 182937 [Multi-domain]  Cd Length: 748  Bit Score: 559.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLsRKAVGK-VTMKIGEGLTGLAAEK 89
Cdd:PRK11061    3 TRLREIVEKVASAPRLNEALDILVTETCLAMDTEVCSVYLADHDRRCYYLMATRGL-KKPRGRtVTLAFDEGIVGLVGRL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  90 RQVVAIQEPEKHPRYRYFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLE 169
Cdd:PRK11061   82 AEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIYRRQLLGVLVVQQRELRQFDESEESFLVTLATQLAAILSQSQLTA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 170 SirkneeeksvFARElektRQTlldkdkeratreprssALRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQK 249
Cdd:PRK11061  162 L----------FGQY----RQT----------------RIRALPASPGVAIAEGWQDATQPLLEQVYPASTLDPALERER 211

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 250 LDLTLEKTRIQTLFLEKRVAERLSQNDAAIF--HSHLmiLEDRSFMEKLRAEIHLGHGVSFALKKIVAEYIEVFERMDDP 327
Cdd:PRK11061  212 LTGALEEAANEFRRYSKRFAAGAQKETAAIFdlYSHL--LNDPRLRRELFAEVDKGSVAEWAVKQVIEKFAEQFAALSDN 289

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 328 YLRERAADIKDIGRRLLANLNDNHQATLQLKCPGILIAREILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPAL 407
Cdd:PRK11061  290 YLRERAGDLRALGQRLLFHLDDSEQGPNAWPERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTV 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 408 VGVKgavkaTTPE----CRVILDANSGCLYIDPAPHVTEEYRRLeADASRELHRLDEFR-NLPPVTSDGQKITLRANIGL 482
Cdd:PRK11061  370 MGAD-----IQPSllhqRLLIVDGYRGELLVDPEPVLLQEYQRL-ISEEIELSRLAEDDvNLPAQLKSGERIKVMLNAGL 443

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 483 VSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVIENFPDYPVTIRSLDIGGDKALPYFsPPKEDNPFMGW 562
Cdd:PRK11061  444 SAEHEEKLGSRVDGVGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFPDKPVTLRTLDIGADKQLPYM-PISEENPCLGW 522

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 563 RSVRVSLDNRDIFRTQIEAIMMAGA-HGPVKLLFPMISGLEEVRACKEVIEEARANlIRENIPFAQSMP-IGVMIEVPSA 640
Cdd:PRK11061  523 RGIRITLDQPEIFLIQVRAMLRANAaTGNLSILLPMVTSIDEVDEARRLIDRAGRE-VEEMLGYEIPKPrIGIMIEVPSM 601

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 641 VMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAILKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVL 720
Cdd:PRK11061  602 VFMLPHLASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMGALLL 681

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1088279055 721 YGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMTDSASIRgHLV 771
Cdd:PRK11061  682 IGLGYRHLSMNGRSVARVKYLLRHIDLAEAENLAQRSLEAQLATEVR-HQV 731
PRK11177 PRK11177
phosphoenolpyruvate-protein phosphotransferase PtsI;
211-776 7.44e-167

phosphoenolpyruvate-protein phosphotransferase PtsI;


Pssm-ID: 183017 [Multi-domain]  Cd Length: 575  Bit Score: 494.15  E-value: 7.44e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 211 GTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILEDR 290
Cdd:PRK11177    4 GILASPGIAFGKALLLKEDEIVINRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 291 SFMEKLRAEIHLGHGVS-FALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNHQATL-QLKCPGILIAREI 368
Cdd:PRK11177   84 ELEQEIIALIKDKHMTAdAAAHSVIEGQAKALEELDDEYLKERAADVRDIGKRLLKNILGLKIIDLsAIQEEVILVAADL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 369 LPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRRLE 448
Cdd:PRK11177  164 TPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELKAVQ 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 449 ADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVIEN 528
Cdd:PRK11177  244 EQYASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFQAYKAVAEA 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 529 FPDYPVTIRSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRACK 608
Cdd:PRK11177  324 MGSQAVIVRTMDIGGDKELPYMNLPKEENPFLGWRAIRIAMDRKEILHDQLRAILRASAFGKLRIMFPMIISVEEVRELK 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 609 EVIEEARANLIRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAILK 688
Cdd:PRK11177  404 AEIEILKQELRDEGKAFDESIEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDRGNELISHLYNPMSPSVLN 483

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 689 VLNFVAKTARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMTDSASIRG 768
Cdd:PRK11177  484 LIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKALAEQALAQPTADELMT 563


                  ....*...
gi 1088279055 769 HLVKVLKE 776
Cdd:PRK11177  564 LVNKFIEE 571
PTS_I_fam TIGR01417
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ...
 209-761 4.90e-156

phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.


Pssm-ID: 273611 [Multi-domain]  Cd Length: 565  Bit Score: 465.81  E-value: 4.90e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 209 LRGTVAYPGLTSGPAHVLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILE 288
Cdd:TIGR01417   1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 289 DRSFMEKLRAEIHLGH-GVSFALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNHQATL-QLKCPGILIAR 366
Cdd:TIGR01417  81 DPELTEEVIELIKKDHkNAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDLsEIQDEVILVAE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 367 EILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRR 446
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 447 LEADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVI 526
Cdd:TIGR01417 241 KQEAVSSEKAELAKLKDKPAITLDGHQVELAANIGTVDDVEGAERNGGEGIGLFRTEFLYMSRDQLPTEEEQFAAYKTVL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 527 ENFPDYPVTIRSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRA 606
Cdd:TIGR01417 321 EAMESDAVIVRTLDIGGDKELPYLNFPKEENPFLGYRAIRLALEREEILRTQLRAILRASAYGKLRIMFPMVATVEEIRA 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 607 CKEVIEEARANLIRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAI 686
Cdd:TIGR01417 401 VKQELEEEKQELNDEGKAFDENIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPYNPAV 480

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1088279055 687 LKVLNFVAKTARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLRDLSSDVARKAAKKVLTMT 761
Cdd:TIGR01417 481 LRLIKLVIDAAKAEGIWVGMCGEMAGDERAIPLLLGLGLRELSMSASSILRIKMIIRKLNIEECKSLAEKALAQP 555
PEP-utilizers_C pfam02896
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ...
 457-743 4.08e-120

PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.


Pssm-ID: 397163 [Multi-domain]  Cd Length: 292  Bit Score: 363.17  E-value: 4.08e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 457 RLDEFRNLPPVTSDGQKITLRANIGLVSDVDIALRNGAEGVGLYRTEFPYMTRGSFPDRDDQYQLYRKVIENFPDYPVTI 536
Cdd:pfam02896   3 ELGKLKDLPAPTADGTKIKVAANIGTPDDAEAALANGAEGIGLYRTEFLFMDRDELPTEDEQFEAYKGVLEAMNGRPVTV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 537 RSLDIGGDKALPYFSPPKEDNPFMGWRSVRVSLDNRDIFRTQIEAIMMAGAHGPVKLLFPMISGLEEVRACKEVIEEARA 616
Cdd:pfam02896  83 RTLDIGGDKELPYLEEPEEMNPFLGWRGIRIGLDRPELFRTQLRAILRASAFGNLRIMFPMVASVEELREAKAIIEEVKE 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 617 NLiRENIPFAQSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAILKVLNFVAKT 696
Cdd:pfam02896 163 EL-DAEVGFDKDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERVAYLYDPLHPAVLRLIKEVIRA 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1088279055 697 ARAQGKGLCLCGEMASDPMNFLVLYGMGINEFSMPSPFIPRIKAFLR 743
Cdd:pfam02896 242 AHRHGKWVGICGEMAGDPSAVPLLVGLGLDEFSMSPDSVPRARALLA 288
PtsP COG3605
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];
11-184 3.14e-58

Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];


Pssm-ID: 442824 [Multi-domain]  Cd Length: 188  Bit Score: 196.27  E-value: 3.14e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKR 90
Cdd:COG3605     4 KALRRISEAVASALDLDEALDRIVRRIAEALGVDVCSIYLLDPDGGRLELRATEGLNPEAVGKVRLPLGEGLVGLVAERG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  91 QVVAIQEPEKHPRYRYFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLES 170
Cdd:COG3605    84 EPLNLADAASHPRFKYFPETGEEGFRSFLGVPIIRRGRVLGVLVVQSREPREFTEEEVEFLVTLAAQLAEAIANAELLGE 163

                         170
                  ....*....|....
gi 1088279055 171 IRKNEEEKSVFARE 184
Cdd:COG3605   164 LRAALAELSLAREE 177
PRK06464 PRK06464
phosphoenolpyruvate synthase; Validated
 367-713 9.90e-42

phosphoenolpyruvate synthase; Validated


Pssm-ID: 235809 [Multi-domain]  Cd Length: 795  Bit Score: 163.76  E-value: 9.90e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 367 EILPSDMASLDHEQI----KGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKA------TTPECRvilDANSGCLYIDP 436
Cdd:PRK06464  387 DVLVTDMTDPDWEPVmkraSAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVlkdgqeVTVSCA---EGDTGYVYEGL 463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 437 APHVTEEyrrleadasrelHRLDEFrnlpPVTsdGQKITLraNiglVSDVDIALR---NGAEGVGLYRTEF--------- 504
Cdd:PRK06464  464 LEFEVEE------------VSLEEM----PET--PTKIMM--N---VGNPERAFDfaaLPNDGVGLARLEFiinnmigvh 520

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 505 ------------------PYMTRGsFPDRDDQY--QLY---RKVIENFPDYPVTIRSLD---------IGGDKAlpyfsP 552
Cdd:PRK06464  521 plallefdqqdadlkaeiEELTAG-YASPEEFYvdKLAegiATVAAAFYPKPVIVRLSDfksneyanlIGGERY-----E 594

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 553 PKEDNPFMGWRSVR--VSLDNRDIFRTQIEAI-----MMaGAHGpVKLLFPMISGLEEVRAckeVIEEARAN-LIR-ENi 623
Cdd:PRK06464  595 PEEENPMLGFRGASryLSESFREAFALECEAIkrvreEM-GLTN-VEVMIPFVRTVEEAEK---VIELLAENgLKRgEN- 668

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 624 pfaqSMPIGVMIEVPSAVMLAPQLAKEVDFFALGTNDLIQYMLAADRNNPLVNKYYDPLHPAILKVLNFVAKTARAQGKG 703
Cdd:PRK06464  669 ----GLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFDERNPAVKKLISMAIKAAKKAGKY 744

                         410
                  ....*....|
gi 1088279055 704 LCLCGEMASD 713
Cdd:PRK06464  745 VGICGQAPSD 754
PRK11377 PRK11377
dihydroxyacetone kinase subunit M; Provisional
 201-435 1.89e-29

dihydroxyacetone kinase subunit M; Provisional


Pssm-ID: 183108 [Multi-domain]  Cd Length: 473  Bit Score: 122.94  E-value: 1.89e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 201 TREPRSSALRGTvayPGLTSGPAhvLDDNLGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIF 280
Cdd:PRK11377  242 TEEVAPPTLRPV---PSPVSGKA--FYYQPVLCTVQAKSTLTVEEEQERLRQAIDFTLLDLMTLTAKAEASGLDDIAAIF 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 281 HSHLMILED---------RSFMEKLRAEihlghgvsFALKKIVAEYIEVFERMDDPYLRERAADIKDIGRRLLANLNDNH 351
Cdd:PRK11377  317 SGHHTLLDDpellaaaseRLQHEHCTAE--------YAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTK 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 352 QATLQLKCPGILIAREILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGC 431
Cdd:PRK11377  389 EELPQFNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPLSHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVKTQR 468


                  ....
gi 1088279055 432 LYID 435
Cdd:PRK11377  469 LNRQ 472
PEP-utilizers_N pfam05524
PEP-utilizing enzyme, N-terminal;
210-332 3.96e-27

PEP-utilizing enzyme, N-terminal;


Pssm-ID: 461671 [Multi-domain]  Cd Length: 125  Bit Score: 106.54  E-value: 3.96e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 210 RGTVAYPGLTSGPAHVLDDN-LGFADALEEGPVDVEKELQKLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILE 288
Cdd:pfam05524   1 KGIGASPGIAIGKAVVLEEPeLEVPDEREVPADDVEAEIARLEAALEAAREELEALAERAAGELGEEEAAIFEAHLMMLE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1088279055 289 DRSFMEKLRAEIHLGH-GVSFALKKIVAEYIEVFERMDDPYLRER 332
Cdd:pfam05524  81 DPELLEEVEELIREGGlNAEAAVKEVVDEFAAMFEAMDDPYLRER 125
GAF COG2203
GAF domain [Signal transduction mechanisms];
11-503 2.68e-26

GAF domain [Signal transduction mechanisms];


Pssm-ID: 441805 [Multi-domain]  Cd Length: 712  Bit Score: 115.29  E-value: 2.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLSRKAVGKVTMkiGEGLTGLAAEKR 90
Cdd:COG2203   193 ALLNEISQALRSALDLEELLQRILELAGELLGADRGAILLVDEDGGELELVAAPGLPEEELGRLPL--GEGLAGRALRTG 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  91 QVVAIQEPEKHPRYR--YFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLL 168
Cdd:COG2203   271 EPVVVNDASTDPRFApsLRELLLALGIRSLLCVPLLVDGRLIGVLALYSKEPRAFTEEDLELLEALADQAAIAIERARLY 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 169 ESIRKNEEEKSVFARELEKTRQTLLDKDKERATREPRSSALRGTVAYPGLTSGPaHVLDDNLGFADALEEGPVDVEKELQ 248
Cdd:COG2203   351 EALEAALAALLQELALLRLLLDLELTLLRLRQLLLELLLALLLLLSLLGAELLL-LLLDAADLSGLLALEGLLLLDLLLL 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 249 KLDLTLEKTRIQTLFLEKRVAERLSQNDAAIFHSHLMILEDRSFMEKLRAEIHLGHGVSFALKKIVAEYIEVFERMDDPY 328
Cdd:COG2203   430 LLLLRRILLLRVLRRLLLGDEEGLVLLLALAELELLEILELLVLLAVILLALALLAALLLLLLLLLALLALSALAVLASL 509

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 329 LRERAADIKDIGRRLLANLNDNHQATLQLKCPGILIAREILPSDMASLDHEQIKGIVTEAGERNSHAVIMAKSLGIPALV 408
Cdd:COG2203   510 LLALLLLLLLLLLLLLLGLLAALAADLLLLAAALLEDLLILLLVLLLERELLTLVGVLLLLGLSVLLIELALALILALAL 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 409 GVKGAVKATTPECRVILDANSGCLYIDPAPHVTEEYRRLEADASRELHRLDEFRNLPPVTSDGQKITLRANIGLVSDVDI 488
Cdd:COG2203   590 LELLLVAVGDLLLLERDLLLLLVLLVRLLLELLVVTLELTVLVVLAAVEDSALLLRLALALASLVLLRALLATELDLILD 669

                         490
                  ....*....|....*
gi 1088279055 489 ALRNGAEGVGLYRTE 503
Cdd:COG2203   670 SSLLLGLLLLGALLL 684
GAF smart00065
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ...
 25-172 2.83e-21

Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.


Pssm-ID: 214500 [Multi-domain]  Cd Length: 149  Bit Score: 90.90  E-value: 2.83e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055   25 DLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKRQVVAIQEPEKHPRY 104
Cdd:smart00065   1 DLEELLQTILEELRQLLGADRVLIYLVDENDRGELVLVAADGLTLPTLGIRFPLDEGLAGRVAETGRPLNIPDVEADPLF 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1088279055  105 RYFKETGEERFHSFLGLPLFDRKTPIGVLTI-QTKEPRKFSAEDISALSTIAFQASSIVINARLLESIR 172
Cdd:smart00065  81 AEDLLGRYQGVRSFLAVPLVADGELVGVLALhNKKSPRPFTEEDEELLQALANQLAIALANAQLYEELR 149
PEP-utilizers pfam00391
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ...
 362-430 1.26e-19

PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.


Pssm-ID: 459796 [Multi-domain]  Cd Length: 73  Bit Score: 83.23  E-value: 1.26e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1088279055 362 ILIAREILPSDMASLDheQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSG 430
Cdd:pfam00391   7 ILVAPDTTPSDTAGLD--KAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
GAF_2 pfam13185
GAF domain; The GAF domain is named after some of the proteins it is found in, including ...
 23-162 4.06e-16

GAF domain; The GAF domain is named after some of the proteins it is found in, including cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. It is also found in guanylyl cyclases and phytochromes. The structure of a GAF domain shows that the domain shares a similar fold with the PAS domain. This domain can bind O2, CO and NO (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 433019 [Multi-domain]  Cd Length: 137  Bit Score: 75.58  E-value: 4.06e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  23 SHDLDETLKNIVTLVSKRMGTEVCSIYLIEDDQetlRLCASKGLSRKAVGKVTMKIGEGLTGLAAEKRQVVAIQEPEKHP 102
Cdd:pfam13185   1 AADLEELLDAVLEAAVELGASAVGFILLVDDDG---RLAAWGGAADELSAALDDPPGEGLVGEALRTGRPVIVNDLAADP 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 103 RYRYFKEtGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIV 162
Cdd:pfam13185  78 AKKGLPA-GHAGLRSFLSVPLVSGGRVVGVLALGSNRPGAFDEEDLELLELLAEQAAIAI 136
GAF pfam01590
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl ...
 25-159 1.27e-15

GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54. This domain can bind biliverdine and phycocyanobilin (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 460259 [Multi-domain]  Cd Length: 133  Bit Score: 74.05  E-value: 1.27e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  25 DLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLrlcASKGLSRKAVGKVTMKIGEGLTglAAEKRQVVAIQEPEKHPRY 104
Cdd:pfam01590   1 DLEEILQTILEELRELLGADRCALYLPDADGLEY---LPPGARWLKAAGLEIPPGTGVT--VLRTGRPLVVPDAAGDPRF 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1088279055 105 -RYFKETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRkFSAEDISALSTIAFQAS 159
Cdd:pfam01590  76 lDPLLLLRNFGIRSLLAVPIIDDGELLGVLVLHHPRPP-FTEEELELLEVLADQVA 130
GAF_3 pfam13492
GAF domain;
25-160 7.61e-11

GAF domain;


Pssm-ID: 433253 [Multi-domain]  Cd Length: 129  Bit Score: 60.46  E-value: 7.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  25 DLDETLKNIVTLVSKRMGTEVCSIYLIEDDQETLRLCASKGLsrKAVGKVTMKIGEGLTGLAAEKRQVVAIQEPEkhpry 104
Cdd:pfam13492   1 SLDEILEALLKLLVRLLGAERAAVYLLDEDGNKLQVAAGYDG--EPDPSESLDADSPLARRALSSGEPISGLGSA----- 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1088279055 105 ryfkETGEERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASS 160
Cdd:pfam13492  74 ----GEDGLPDGPALVVPLVAGRRVIGVLALASSKPRAFDAEDLRLLESLAAQIAT 125
PykA2 COG3848
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
379-433 3.47e-08

Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];


Pssm-ID: 443058  Cd Length: 321  Bit Score: 56.06  E-value: 3.47e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1088279055 379 EQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLY 433
Cdd:COG3848   260 EKAAGIITEEGGLTSHAAIVGLELGIPVIVGAEGATEILKDGQVVTVDAERGVVY 314
MsrC COG1956
GAF domain-containing protein, putative methionine-R-sulfoxide reductase [Defense mechanisms, ...
 11-155 9.83e-07

GAF domain-containing protein, putative methionine-R-sulfoxide reductase [Defense mechanisms, Signal transduction mechanisms];


Pssm-ID: 441559 [Multi-domain]  Cd Length: 156  Bit Score: 49.06  E-value: 9.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055  11 TILEDISTLIHQSHDLDETLKNIVTLVSKRM-GTEVCSIYLIEDDQEtLRLCASKGlsrkAVGKVTMKIGEGLTGLAAEK 89
Cdd:COG1956    11 ELLAQLSALLAGETDLIANLANISALLFEALpDYNWVGFYLVDGGGE-LVLGPFQG----PPACTRIPFGKGVCGTAAAE 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1088279055  90 RQVVAIQEPEKHPRY-------RyfketgeerfhSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIA 155
Cdd:COG1956    86 GETQLVPDVHAFPGHiacdsasR-----------SEIVVPIFKDGEVIGVLDIDSPTPGRFDEEDQAGLEALA 147
PpsA COG0574
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ...
 362-430 9.94e-07

Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 440339 [Multi-domain]  Cd Length: 455  Bit Score: 52.14  E-value: 9.94e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1088279055 362 ILIAREILPSD---MAsldheQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSG 430
Cdd:COG0574   386 ILVRDETDPDDvpgMK-----AAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITVDGTTG 452
PRK06354 PRK06354
pyruvate kinase; Provisional
 361-433 1.95e-06

pyruvate kinase; Provisional


Pssm-ID: 235784 [Multi-domain]  Cd Length: 590  Bit Score: 51.46  E-value: 1.95e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1088279055 361 GILIAREILPSDMASLdhEQIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLY 433
Cdd:PRK06354  513 DILVTPSTDADMIPAI--EKAAAIITEEGGLTSHAAVVGLRLGIPVIVGVKNATSLIKDGQIITVDAARGVVY 583
FhlA COG3604
FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis ...
 112-159 4.66e-05

FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];


Pssm-ID: 442823 [Multi-domain]  Cd Length: 338  Bit Score: 46.38  E-value: 4.66e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1088279055 112 EERFHSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQAS 159
Cdd:COG3604    70 ARERQLFLGVPLRVGGEVLGVLTLDSRRPGAFSEEDLRLLETLASLAA 117
PRK05878 PRK05878
pyruvate phosphate dikinase; Provisional
 224-478 5.97e-05

pyruvate phosphate dikinase; Provisional


Pssm-ID: 235635 [Multi-domain]  Cd Length: 530  Bit Score: 46.28  E-value: 5.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 224 HVLDDNLGFADALEEGPVDVekelQKLDLTLEKTRIqtLFLEKRVAERLSQndAAIFHShlMILEDRSFMEKlrAEihlg 303
Cdd:PRK05878  258 AVYDELMAAARTLERLGRDV----QDIEFTVESGKL--WLLQTRSAKRSAQ--AAVRLA--LQLHDEGLIDD--AE---- 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 304 hgvsfALKKIVAEYIEVFERmddPYLRERAAdikdIGRRLLANlndNHQAtlqlkCPGILIAREILPSD----MASLDHE 379
Cdd:PRK05878  322 -----ALRRVTPTHVETLLR---PSLQPEAR----LAAPLLAK---GLPA-----CPGVVSGTAYTDVDealdAADRGEP 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 380 QI-----------------KGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGCLY------IDP 436
Cdd:PRK05878  382 VIlvrdhtrpddvhgmlaaQGIVTEVGGATSHAAVVSRELGRVAVVGCGAGVAAALAGKEITVDGYEGEVRqgvlalSAW 461

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1088279055 437 APHVTEEYRRL----EADASRELHRLDEFRNLPPVTSDGQKITLRA 478
Cdd:PRK05878  462 SESDTPELRELadiaQRISPLRAHASGDYPRLDDDSDDAVRAALAA 507
PRK06241 PRK06241
phosphoenolpyruvate synthase; Validated
 380-434 2.10e-04

phosphoenolpyruvate synthase; Validated


Pssm-ID: 235751 [Multi-domain]  Cd Length: 871  Bit Score: 44.88  E-value: 2.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1088279055 380 QIKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSGclYI 434
Cdd:PRK06241  814 SIKGLVTEVGGLMTHGAVIAREYGIPAVVGVENATKLIKDGQRIRVDGTEG--YV 866
PRK05022 PRK05022
nitric oxide reductase transcriptional regulator NorR;
116-180 2.43e-04

nitric oxide reductase transcriptional regulator NorR;


Pssm-ID: 235331 [Multi-domain]  Cd Length: 509  Bit Score: 44.39  E-value: 2.43e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1088279055 116 HSFLGLPLFDRKTPIGVLTIQTKEPRKFSAEDISALSTIAFQASSIVINARLLESIRK-NEEEKSV 180
Cdd:PRK05022  110 HDCMGLPLFVDGRLIGALTLDALDPGQFDAFSDEELRALAALAAATLRNALLIEQLESqAELPQDV 175
CitE COG2301
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
565-702 5.00e-04

Citrate lyase beta subunit [Carbohydrate transport and metabolism];


Pssm-ID: 441876  Cd Length: 288  Bit Score: 42.83  E-value: 5.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1088279055 565 VRV-SLDNRDiFRTQIEAIMMAGAHGpvkLLFPMISGLEEVRACKEVIEEARANlirenipfAQSMPIGVMIEVPSAVML 643
Cdd:COG2301    67 VRInALDTPW-GLDDLAALVGAGLDG---IVLPKVESAEDVRALAALLTELEAE--------GGSIPLMALIETARGLLN 134

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1088279055 644 APQLAKE---VDFFALGTNDL---IQYMLAADRnnplvnkyyDPLHPAILKVLNfvakTARAQGK 702
Cdd:COG2301   135 AAEIAAAsprVEALVFGAEDLaadLGARRTRDG---------DELLYARSRIVL----AARAAGL 186
PRK08296 PRK08296
hypothetical protein; Provisional
 381-430 2.71e-03

hypothetical protein; Provisional


Pssm-ID: 181362  Cd Length: 603  Bit Score: 41.18  E-value: 2.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1088279055 381 IKGIVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSG 430
Cdd:PRK08296  548 IKATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRLRVDGTKG 597
PRK05865 PRK05865
sugar epimerase family protein;
384-430 4.57e-03

sugar epimerase family protein;


Pssm-ID: 235630 [Multi-domain]  Cd Length: 854  Bit Score: 40.41  E-value: 4.57e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1088279055 384 IVTEAGERNSHAVIMAKSLGIPALVGVKGAVKATTPECRVILDANSG 430
Cdd:PRK05865  786 VVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGALVEVDGATG 832
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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