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Conserved domains on  [gi|108793363|ref|YP_637087|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Eudyptes chrysocome]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.18e-50

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 160.30  E-value: 1.18e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGEWPVV--VYGVGLVLVLAIGLGVGGFEGWKFGVNTVDSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVgyVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 108793363 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.18e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 160.30  E-value: 1.18e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGEWPVV--VYGVGLVLVLAIGLGVGGFEGWKFGVNTVDSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVgyVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 108793363 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 1.09e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 56.36  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   17 LAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPVGWGEWPVVVYGVGLVL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 108793363   97 VLAIGLGVGGFEGWKFGVNTVDSGGVVPIRLdfSGVALFYScGVGMFLVAGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEA--IGELLFTD-YLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.18e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 160.30  E-value: 1.18e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGEWPVV--VYGVGLVLVLAIGLGVGGFEGWKFGVNTVDSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVgyVVGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 108793363 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 4.21e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 158.77  E-value: 4.21e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGEWPVVVYGVGLVLVLAIGLGV---GGFEGWKFGVNTVDSGGVVpiRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVV 157
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLfwgGWYEGSWVVVDELKEFSVL--RGDVGGVALMYSSGGGMLVICAWVLLLTLFVV 158

                        170
                 ....*....|....*
gi 108793363 158 LELVRGLSRGAIRAV 172
Cdd:MTH00138 159 LELTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 8.20e-46

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 148.07  E-value: 8.20e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGEWPVVVYGVGLVLVLAIGLGVGGFEGWKFGVNTVDSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVVLEL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 108793363 161 VRGLSRGAIRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 2.38e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 100.65  E-value: 2.38e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGE----WPVVVYGVGLVLVLAIGLGVGGFEGWKFGVNTV------DSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGL 150
Cdd:MTH00109  82 TWVSnkvvLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 108793363 151 LLTLFVVLELVRG 163
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.57e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 93.51  E-value: 1.57e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLFLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 GWGEWPVVVYGVGLVLvlaiGLGVGGFEGWKFGVNTVDSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVVLEL 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLL----GLGFVGFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                        170
                 ....*....|..
gi 108793363 161 VRGLSRGAIRAV 172
Cdd:MTH00214 157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-171 1.87e-15

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 69.55  E-value: 1.87e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   1 MTYLVLflgVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPV 80
Cdd:MTH00045   2 VFYLFL---ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363  81 --GWGEwpvvvygVGLVLVLAIGLGVGGFEGWkfgVNTVDSGGVVPIRLDFSGVALFYSCGVGMFLVAGWGLLLTLFVVL 158
Cdd:MTH00045  79 vsNLGE-------VLVLSLLLSLWVFISFDNF---LELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVAL 148

                        170
                 ....*....|...
gi 108793363 159 ELVRGLSRGAIRA 171
Cdd:MTH00045 149 VISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 1.09e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 56.36  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108793363   17 LAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVALAADPFPVGWGEWPVVVYGVGLVL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 108793363   97 VLAIGLGVGGFEGWKFGVNTVDSGGVVPIRLdfSGVALFYScGVGMFLVAGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEA--IGELLFTD-YLLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 5.14e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 38.94  E-value: 5.14e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 108793363   7 FLGVCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLVSLGVSFVALVLFMVYLGGMLVVFVYSVAL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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