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Conserved domains on  [gi|108561549|ref|YP_626697|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Onychodactylus fischeri]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009550)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 7.85e-69

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214415  Cd Length: 172  Bit Score: 206.24  E-value: 7.85e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  81 AWGSWSVLIYVFLYFVLMSLGYFFFNCNMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLSGWVLLLTLFVVLEV 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 108561549 161 TRGLSYGSLRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
 
Name Accession Description Interval E-value
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 7.85e-69

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 206.24  E-value: 7.85e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  81 AWGSWSVLIYVFLYFVLMSLGYFFFNCNMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLSGWVLLLTLFVVLEV 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 108561549 161 TRGLSYGSLRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-146 4.88e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 35.56  E-value: 4.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   17 VAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASL-AAEPYPEAWGSWSVLIYVFLYF 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 108561549   96 VLMSLGYFFFncnMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLS 146
Cdd:pfam00499  81 LLLALLLLVL---LSASLTPAAAAAAPDVGNIEAIGELLFTDYLLPFELAS 128
 
Name Accession Description Interval E-value
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 7.85e-69

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 206.24  E-value: 7.85e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  81 AWGSWSVLIYVFLYFVLMSLGYFFFNCNMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLSGWVLLLTLFVVLEV 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 108561549 161 TRGLSYGSLRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.23e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 155.30  E-value: 1.23e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  81 AWGSWSVLIYVFLYFVLMSL-GYFFFNCNMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLSGWVLLLTLFVVLE 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLaAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 108561549 160 VTRGLSYGSLRAV 172
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 3.91e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 107.91  E-value: 3.91e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  81 AWGSWSVLIYV--FLYFVLMSLGYFFFNCNMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLSGWVLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVvgFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 108561549 159 EVTRGLSYGSLRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-148 7.39e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 86.78  E-value: 7.39e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 108561549  81 AWGSWSVLIYVFLYFVLMSLG---YFFFNCNMSVEFLFTNY-------NIEYSAVGNDWGGIGMMYSFGGWFLVLSGW 148
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLlvlYVLKDDEVEVVFNFNGLgdwviydTGGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.57e-19

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 80.42  E-value: 1.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLGFVFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  81 AWGSWSVLIYVFLYFVLMSLGYFFFNCNMSVEFLFTNYNIEYSAVgndwGGIGMMYSFGGWFLVLSGWVLLLTLFVVLEV 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                        170
                 ....*....|..
gi 108561549 161 TRGLSYGSLRAV 172
Cdd:MTH00214 157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-171 1.47e-15

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 69.93  E-value: 1.47e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   1 MIYLALLAMLgfvFGLVAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASLAAEPYP- 79
Cdd:MTH00045   2 VFYLFLILML---FGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPs 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549  80 -EAWGSWSVLIYVFLYFVLMSLGYFFFNCNMSVEFLftnynieysaVGNDWGGIGMMYSFGGWFLVLSGWVLLLTLFVVL 158
Cdd:MTH00045  79 vSNLGEVLVLSLLLSLWVFISFDNFLELSNNNWSLV----------SLSDLVGSSELYNSGGLYLLLGGFILLVALVVAL 148

                        170
                 ....*....|...
gi 108561549 159 EVTRGLSYGSLRA 171
Cdd:MTH00045 149 VISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-146 4.88e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 35.56  E-value: 4.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 108561549   17 VAVASNPSPYFAALGLVLAAVCGCWVLVELGISFLSLVLLLIYLGGMLVVFAYSASL-AAEPYPEAWGSWSVLIYVFLYF 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 108561549   96 VLMSLGYFFFncnMSVEFLFTNYNIEYSAVGNDWGGIGMMYSFGGWFLVLS 146
Cdd:pfam00499  81 LLLALLLLVL---LSASLTPAAAAAAPDVGNIEAIGELLFTDYLLPFELAS 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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