NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1084827072|gb|OGQ60795|]
View 

hypothetical protein A3J24_10345 [Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_53_8]

Protein Classification

SoxR reducing system RseC family protein( domain architecture ID 10006910)

SoxR reducing system RseC family protein, may play a role in the reduction of the iron-sulfur cluster regulatory protein SoxR

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
RseC COG3086
RseC, positive regulator of sigma E activity [Signal transduction mechanisms];
5-149 4.49e-34

RseC, positive regulator of sigma E activity [Signal transduction mechanisms];


:

Pssm-ID: 442320  Cd Length: 149  Bit Score: 116.52  E-value: 4.49e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072   5 MEEQGIVVELKaNNTALVKAKRTSTCESCASKKSCSTRS-----SGDDMFVETENTIGASKGDHVVFAVSAGTIMKTGLL 79
Cdd:COG3086     2 IEETGTVVAVE-GGTAWVETQRKSACGSCAAKSGCGTGLlsklfPSKEHRLEVPNPLGLKVGDRVEVGIPESSLLKAALL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072  80 VYLMPVIAFLAGIVLGQkvvapMLPNINSDLVSGALGLIFLIDAFVLLKIYNQYMEKKGGiMRPKLLRKL 149
Cdd:COG3086    81 VYLLPLLGLLLGALLGQ-----ALGPGGSELLAALGGLLGLALGFLLARRLSRRLAKKSK-YQPVILRIL 144
 
Name Accession Description Interval E-value
RseC COG3086
RseC, positive regulator of sigma E activity [Signal transduction mechanisms];
5-149 4.49e-34

RseC, positive regulator of sigma E activity [Signal transduction mechanisms];


Pssm-ID: 442320  Cd Length: 149  Bit Score: 116.52  E-value: 4.49e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072   5 MEEQGIVVELKaNNTALVKAKRTSTCESCASKKSCSTRS-----SGDDMFVETENTIGASKGDHVVFAVSAGTIMKTGLL 79
Cdd:COG3086     2 IEETGTVVAVE-GGTAWVETQRKSACGSCAAKSGCGTGLlsklfPSKEHRLEVPNPLGLKVGDRVEVGIPESSLLKAALL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072  80 VYLMPVIAFLAGIVLGQkvvapMLPNINSDLVSGALGLIFLIDAFVLLKIYNQYMEKKGGiMRPKLLRKL 149
Cdd:COG3086    81 VYLLPLLGLLLGALLGQ-----ALGPGGSELLAALGGLLGLALGFLLARRLSRRLAKKSK-YQPVILRIL 144
RseC_MucC pfam04246
Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins ...
 11-147 2.31e-31

Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins represents a positive regulator of the sigma(E) transcription factor, namely RseC/MucC. The sigma(E) transcription factor is up-regulated by cell envelope protein misfolding, and regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions). In Pseudomonas aeruginosa, de-repression of sigma(E) is associated with the alginate-overproducing phenotype characteriztic of chronic respiratory tract colonization in cystic fibrosis patients. The mechanism by which RseC/MucC positively regulates the sigma(E) transcription factor is unknown. RseC is also thought to have a role in thiamine biosynthesis in Salmonella typhimurium. In addition, this family also includes an N-terminal part of RnfF, a Rhodobacter capsulatus protein, of unknown function, that is essential for nitrogen fixation. This protein also contains an ApbE domain pfam02424, which is itself involved in thiamine biosynthesis.


Pssm-ID: 461236  Cd Length: 130  Bit Score: 108.82  E-value: 2.31e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072  11 VVELKaNNTALVKAKRTSTCESCASKKSCSTRSSGD-DMFVETENTIGASKGDHVVFAVSAGTIMKTGLLVYLMPVIAFL 89
Cdd:pfam04246   1 VVAVE-GGTAWVEIERKSACGSCAARSGCKLGASGSkEKIIEVANPIGAKVGDRVEVGIPESSLLKAALLVYLLPLLGLI 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1084827072  90 AGIVLGQKVVApmlpniNSDLVSGALGLIFLIDAFVLLKIYNQYMEKKGGiMRPKLLR 147
Cdd:pfam04246  80 LGALLGQALLG------GSELAAALGGLLGLALGFLILRLLDRRLKKKGK-FQPVILR 130
PRK10862 PRK10862
SoxR-reducing system protein RseC;
5-119 5.69e-05

SoxR-reducing system protein RseC;


Pssm-ID: 182788  Cd Length: 154  Bit Score: 40.72  E-value: 5.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072   5 MEEQGIVVELKaNNTALVKAKRTSTCESCASKKSCSTRSSgDDMFVETENTIGA------SKGDHVVFAVSAGTIMKTGL 78
Cdd:PRK10862    2 IKEWATVVSWQ-NGIALLRCEVKAGCSSCASRAGCGSRLL-NKLGPQTTHQLVVpssqplVPGQKVELGIAEGSLLRSAL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1084827072  79 LVYLMPVIAFLAGIVLGQKVVAPMLPNINSDLVSGALGLIF 119
Cdd:PRK10862   80 LVYMTPLVGLFLGAALFQLLFGSDLAALCGALLGGVGGFLL 120
 
Name Accession Description Interval E-value
RseC COG3086
RseC, positive regulator of sigma E activity [Signal transduction mechanisms];
5-149 4.49e-34

RseC, positive regulator of sigma E activity [Signal transduction mechanisms];


Pssm-ID: 442320  Cd Length: 149  Bit Score: 116.52  E-value: 4.49e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072   5 MEEQGIVVELKaNNTALVKAKRTSTCESCASKKSCSTRS-----SGDDMFVETENTIGASKGDHVVFAVSAGTIMKTGLL 79
Cdd:COG3086     2 IEETGTVVAVE-GGTAWVETQRKSACGSCAAKSGCGTGLlsklfPSKEHRLEVPNPLGLKVGDRVEVGIPESSLLKAALL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072  80 VYLMPVIAFLAGIVLGQkvvapMLPNINSDLVSGALGLIFLIDAFVLLKIYNQYMEKKGGiMRPKLLRKL 149
Cdd:COG3086    81 VYLLPLLGLLLGALLGQ-----ALGPGGSELLAALGGLLGLALGFLLARRLSRRLAKKSK-YQPVILRIL 144
RseC_MucC pfam04246
Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins ...
 11-147 2.31e-31

Positive regulator of sigma(E), RseC/MucC; This bacterial family of integral membrane proteins represents a positive regulator of the sigma(E) transcription factor, namely RseC/MucC. The sigma(E) transcription factor is up-regulated by cell envelope protein misfolding, and regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions). In Pseudomonas aeruginosa, de-repression of sigma(E) is associated with the alginate-overproducing phenotype characteriztic of chronic respiratory tract colonization in cystic fibrosis patients. The mechanism by which RseC/MucC positively regulates the sigma(E) transcription factor is unknown. RseC is also thought to have a role in thiamine biosynthesis in Salmonella typhimurium. In addition, this family also includes an N-terminal part of RnfF, a Rhodobacter capsulatus protein, of unknown function, that is essential for nitrogen fixation. This protein also contains an ApbE domain pfam02424, which is itself involved in thiamine biosynthesis.


Pssm-ID: 461236  Cd Length: 130  Bit Score: 108.82  E-value: 2.31e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072  11 VVELKaNNTALVKAKRTSTCESCASKKSCSTRSSGD-DMFVETENTIGASKGDHVVFAVSAGTIMKTGLLVYLMPVIAFL 89
Cdd:pfam04246   1 VVAVE-GGTAWVEIERKSACGSCAARSGCKLGASGSkEKIIEVANPIGAKVGDRVEVGIPESSLLKAALLVYLLPLLGLI 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1084827072  90 AGIVLGQKVVApmlpniNSDLVSGALGLIFLIDAFVLLKIYNQYMEKKGGiMRPKLLR 147
Cdd:pfam04246  80 LGALLGQALLG------GSELAAALGGLLGLALGFLILRLLDRRLKKKGK-FQPVILR 130
PRK10862 PRK10862
SoxR-reducing system protein RseC;
5-119 5.69e-05

SoxR-reducing system protein RseC;


Pssm-ID: 182788  Cd Length: 154  Bit Score: 40.72  E-value: 5.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084827072   5 MEEQGIVVELKaNNTALVKAKRTSTCESCASKKSCSTRSSgDDMFVETENTIGA------SKGDHVVFAVSAGTIMKTGL 78
Cdd:PRK10862    2 IKEWATVVSWQ-NGIALLRCEVKAGCSSCASRAGCGSRLL-NKLGPQTTHQLVVpssqplVPGQKVELGIAEGSLLRSAL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1084827072  79 LVYLMPVIAFLAGIVLGQKVVAPMLPNINSDLVSGALGLIF 119
Cdd:PRK10862   80 LVYMTPLVGLFLGAALFQLLFGSDLAALCGALLGGVGGFLL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH