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Conserved domains on  [gi|1084513199|gb|OGN75336|]
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hypothetical protein A2X25_01400 [Chloroflexi bacterium GWB2_49_20]

Protein Classification

Fer4_22 domain-containing protein( domain architecture ID 12182539)

Fer4_22 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fer4_22 pfam17179
4Fe-4S dicluster domain;
221-319 3.52e-40

4Fe-4S dicluster domain;


:

Pssm-ID: 465372 [Multi-domain]  Cd Length: 95  Bit Score: 136.15  E-value: 3.52e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 221 RCLSCRVCAYVCPTCRCFITRDEPVQGKgEFERVRCWDSCNGANYRMVAGGHRPRSEKSERLRNRFLCKFLYYASQYDls 300
Cdd:pfam17179   1 RCLSCGACTFVCPTCFCFDVQDEVENGK-SGERRRVWDSCMFEGFTRMAGGHNPRPTKGERYRQRFMHKLSYFPDRFG-- 77

                          90
                  ....*....|....*....
gi 1084513199 301 eTTSCTGCGRCVDACPVNV 319
Cdd:pfam17179  78 -RSGCVGCGRCITWCPVGI 95
 
Name Accession Description Interval E-value
Fer4_22 pfam17179
4Fe-4S dicluster domain;
221-319 3.52e-40

4Fe-4S dicluster domain;


Pssm-ID: 465372 [Multi-domain]  Cd Length: 95  Bit Score: 136.15  E-value: 3.52e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 221 RCLSCRVCAYVCPTCRCFITRDEPVQGKgEFERVRCWDSCNGANYRMVAGGHRPRSEKSERLRNRFLCKFLYYASQYDls 300
Cdd:pfam17179   1 RCLSCGACTFVCPTCFCFDVQDEVENGK-SGERRRVWDSCMFEGFTRMAGGHNPRPTKGERYRQRFMHKLSYFPDRFG-- 77

                          90
                  ....*....|....*....
gi 1084513199 301 eTTSCTGCGRCVDACPVNV 319
Cdd:pfam17179  78 -RSGCVGCGRCITWCPVGI 95
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 220-328 6.51e-07

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 50.46  E-value: 6.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 220 DRCLSCRVCAYVCPTCRcfITRDEPvqgkgefervrcwdscnganyrmvaggHRPRsekserLRNRFLCKFLYYASQYDL 299
Cdd:COG0247    78 DACVGCGFCRAMCPSYK--ATGDEK---------------------------DSPR------GRINLLREVLEGELPLDL 122

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1084513199 300 SETT-----SCTGCGRCVDACPVNVDITEILNDF 328
Cdd:COG0247   123 SEEVyevldLCLTCKACETACPSGVDIADLIAEA 156
PRK07569 PRK07569
bidirectional hydrogenase complex protein HoxU; Validated
 207-316 5.77e-05

bidirectional hydrogenase complex protein HoxU; Validated


Pssm-ID: 181037 [Multi-domain]  Cd Length: 234  Bit Score: 43.87  E-value: 5.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 207 ASHfsdEYWQMVSDRCLSCRVCAYVCptcrcfitrdepvqgkGEFERVRCWD-SCNGANYRMVAGGHRPrsekserlrnr 285
Cdd:PRK07569  136 ISH---PRFGIDHNRCVLCTRCVRVC----------------DEIEGAHTWDvAGRGAKSRVITDLNQP----------- 185

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1084513199 286 flckflyyasqydLSETTSCTGCGRCVDACP 316
Cdd:PRK07569  186 -------------WGTSETCTSCGKCVQACP 203
 
Name Accession Description Interval E-value
Fer4_22 pfam17179
4Fe-4S dicluster domain;
221-319 3.52e-40

4Fe-4S dicluster domain;


Pssm-ID: 465372 [Multi-domain]  Cd Length: 95  Bit Score: 136.15  E-value: 3.52e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 221 RCLSCRVCAYVCPTCRCFITRDEPVQGKgEFERVRCWDSCNGANYRMVAGGHRPRSEKSERLRNRFLCKFLYYASQYDls 300
Cdd:pfam17179   1 RCLSCGACTFVCPTCFCFDVQDEVENGK-SGERRRVWDSCMFEGFTRMAGGHNPRPTKGERYRQRFMHKLSYFPDRFG-- 77

                          90
                  ....*....|....*....
gi 1084513199 301 eTTSCTGCGRCVDACPVNV 319
Cdd:pfam17179  78 -RSGCVGCGRCITWCPVGI 95
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 220-328 6.51e-07

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 50.46  E-value: 6.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 220 DRCLSCRVCAYVCPTCRcfITRDEPvqgkgefervrcwdscnganyrmvaggHRPRsekserLRNRFLCKFLYYASQYDL 299
Cdd:COG0247    78 DACVGCGFCRAMCPSYK--ATGDEK---------------------------DSPR------GRINLLREVLEGELPLDL 122

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1084513199 300 SETT-----SCTGCGRCVDACPVNVDITEILNDF 328
Cdd:COG0247   123 SEEVyevldLCLTCKACETACPSGVDIADLIAEA 156
LutB COG1139
L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and ...
 305-325 2.53e-05

L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and conversion];


Pssm-ID: 440754 [Multi-domain]  Cd Length: 465  Bit Score: 45.49  E-value: 2.53e-05
                          10        20
                  ....*....|....*....|.
gi 1084513199 305 CTGCGRCVDACPVNVDITEIL 325
Cdd:COG1139   363 STLCGACTEVCPVKIPIPELL 383
PRK07569 PRK07569
bidirectional hydrogenase complex protein HoxU; Validated
 207-316 5.77e-05

bidirectional hydrogenase complex protein HoxU; Validated


Pssm-ID: 181037 [Multi-domain]  Cd Length: 234  Bit Score: 43.87  E-value: 5.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 207 ASHfsdEYWQMVSDRCLSCRVCAYVCptcrcfitrdepvqgkGEFERVRCWD-SCNGANYRMVAGGHRPrsekserlrnr 285
Cdd:PRK07569  136 ISH---PRFGIDHNRCVLCTRCVRVC----------------DEIEGAHTWDvAGRGAKSRVITDLNQP----------- 185

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1084513199 286 flckflyyasqydLSETTSCTGCGRCVDACP 316
Cdd:PRK07569  186 -------------WGTSETCTSCGKCVQACP 203
HdrC COG1150
Heterodisulfide reductase, subunit C [Energy production and conversion];
221-325 8.80e-05

Heterodisulfide reductase, subunit C [Energy production and conversion];


Pssm-ID: 440764 [Multi-domain]  Cd Length: 79  Bit Score: 40.27  E-value: 8.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 221 RCLSCRVCAYVCPTCRcfitrdepvqgkgefervrcwdscnganyrmvAGGHRPRsekseRLRNRFLCKFLYYAsqYDLS 300
Cdd:COG1150     4 KCYQCGTCTASCPVAR--------------------------------AMDYNPR-----KIIRLAQLGLKEEV--LKSD 44

                          90       100
                  ....*....|....*....|....*
gi 1084513199 301 ETTSCTGCGRCVDACPVNVDITEIL 325
Cdd:COG1150    45 SIWLCVSCYTCTERCPRGIDIADVM 69
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 302-319 2.10e-03

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 36.23  E-value: 2.10e-03
                          10
                  ....*....|....*...
gi 1084513199 302 TTSCTGCGRCVDACPVNV 319
Cdd:COG1146     7 TDKCIGCGACVEVCPVDV 24
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 221-319 3.02e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 35.75  E-value: 3.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1084513199 221 RCLSCRVCAYVCPTCRCFITRDepvqgkgefervrcwdscnganyrmvagGHRPRSEKSERLRNRFLCKFLYYASQYdls 300
Cdd:pfam13183   1 RCIRCGACLAACPVYLVTGGRF----------------------------PGDPRGGAAALLGRLEALEGLAEGLWL--- 49

                          90
                  ....*....|....*....
gi 1084513199 301 ettsCTGCGRCVDACPVNV 319
Cdd:pfam13183  50 ----CTLCGACTEVCPVGI 64
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 301-318 3.19e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 38.97  E-value: 3.19e-03
                          10
                  ....*....|....*...
gi 1084513199 301 ETTSCTGCGRCVDACPVN 318
Cdd:COG4656   362 EEQPCIRCGRCVDACPMG 379
COG1453 COG1453
Predicted oxidoreductase of the aldo/keto reductase family [General function prediction only];
304-331 3.31e-03

Predicted oxidoreductase of the aldo/keto reductase family [General function prediction only];


Pssm-ID: 441062 [Multi-domain]  Cd Length: 365  Bit Score: 39.03  E-value: 3.31e-03
                          10        20
                  ....*....|....*....|....*...
gi 1084513199 304 SCTGCGRCVDACPVNVDITEILNDFGRL 331
Cdd:COG1453   332 ACIECGACEERCPQGLDIPELLKEAHEL 359
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 305-319 3.36e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 38.44  E-value: 3.36e-03
                          10
                  ....*....|....*
gi 1084513199 305 CTGCGRCVDACPVNV 319
Cdd:COG2878   169 CTGCGLCVEACPVDC 183
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 305-319 7.75e-03

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 33.38  E-value: 7.75e-03
                          10
                  ....*....|....*
gi 1084513199 305 CTGCGRCVDACPVNV 319
Cdd:pfam00037   8 CIGCGACVEVCPVGA 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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