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Conserved domains on  [gi|1083682061|gb|OGH69373|]
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MAG: hypothetical protein A3D53_00050 [Candidatus Magasanikbacteria bacterium RIFCSPHIGHO2_02_FULL_45_10]

Protein Classification

bifunctional oligoribonuclease/PAP phosphatase NrnA( domain architecture ID 11427717)

bifunctional oligoribonuclease/PAP phosphatase NrnA is a DHH family phosphoesterase that exhibits 3'(2')-phosphoadenosine 5'-phosphate (PAP) phosphatase, as well as oligoribonuclease activity

EC:  3.1.3.7
Gene Ontology:  GO:0003676|GO:0008441|GO:0004527

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NrnA COG0618
nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs [Nucleotide transport and ...
7-372 1.48e-41

nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs [Nucleotide transport and metabolism, Signal transduction mechanisms];


:

Pssm-ID: 440383 [Multi-domain]  Cd Length: 312  Bit Score: 148.03  E-value: 1.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061   7 QQVQKLFEESKYVLVVYNGKSNGDATASAIALKILLEKLKKQVDIVAAGySVPKKFHFLPQTDTIKsdisqvqkfiikld 86
Cdd:COG0618     1 EELAELLKKADRILILTHVNPDGDALGSALALALLLRALGKEVTIVYPG-EIPHELAFLPGADEIV-------------- 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061  87 vsqspietisydvrdnqlslyltpkhgiisknelRTAQSSFKYDLIITLHVSDLVSLGaafnDNADLFYKTS-ILNIDHE 165
Cdd:COG0618    66 ----------------------------------RLEDVDLEYDLVIVVDTSSPDRIG----DLAELLEKAKpVIVIDHH 107
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061 166 PNNERFGQVNLIDLTSTSVSETVYKTIKKIHsGLIDAEMATALLAGMTVATKSFRNYNITPVTLQLASELITYGADREKI 245
Cdd:COG0618   108 PSNDDFGDFNDVDPDAGATSEIIYELLKELG-IEIDPEIATALYTGIVTDTGSFRYSNTTPRDFRAAAELLEKGADLDLI 186
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061 246 MENLYRTRSIAALKLWGQALSHLEHDAKHSIVWTALTRDDFTRSGSTEEDLQGIIDELIgNSPEAKTIVLIFEAADKKIT 325
Cdd:COG0618   187 ARILYPSLSLEQLKLLGRALENLEVLEDGKVAYSYLTKEDLEEFGATPDDTEGLVDYLL-SIEGVEVAVVFGEVEDGEIK 265
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1083682061 326 ALVATEKSGDALELTKKFSPQGNKKTASIQFDGLTLKEVEIKLLDEL 372
Cdd:COG0618   266 VSLRSKGRVDVGEIAREFGGGGHARAAGATIPGLDLEEVVEKLLEAL 312
 
Name Accession Description Interval E-value
NrnA COG0618
nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs [Nucleotide transport and ...
7-372 1.48e-41

nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs [Nucleotide transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440383 [Multi-domain]  Cd Length: 312  Bit Score: 148.03  E-value: 1.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061   7 QQVQKLFEESKYVLVVYNGKSNGDATASAIALKILLEKLKKQVDIVAAGySVPKKFHFLPQTDTIKsdisqvqkfiikld 86
Cdd:COG0618     1 EELAELLKKADRILILTHVNPDGDALGSALALALLLRALGKEVTIVYPG-EIPHELAFLPGADEIV-------------- 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061  87 vsqspietisydvrdnqlslyltpkhgiisknelRTAQSSFKYDLIITLHVSDLVSLGaafnDNADLFYKTS-ILNIDHE 165
Cdd:COG0618    66 ----------------------------------RLEDVDLEYDLVIVVDTSSPDRIG----DLAELLEKAKpVIVIDHH 107
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061 166 PNNERFGQVNLIDLTSTSVSETVYKTIKKIHsGLIDAEMATALLAGMTVATKSFRNYNITPVTLQLASELITYGADREKI 245
Cdd:COG0618   108 PSNDDFGDFNDVDPDAGATSEIIYELLKELG-IEIDPEIATALYTGIVTDTGSFRYSNTTPRDFRAAAELLEKGADLDLI 186
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061 246 MENLYRTRSIAALKLWGQALSHLEHDAKHSIVWTALTRDDFTRSGSTEEDLQGIIDELIgNSPEAKTIVLIFEAADKKIT 325
Cdd:COG0618   187 ARILYPSLSLEQLKLLGRALENLEVLEDGKVAYSYLTKEDLEEFGATPDDTEGLVDYLL-SIEGVEVAVVFGEVEDGEIK 265
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1083682061 326 ALVATEKSGDALELTKKFSPQGNKKTASIQFDGLTLKEVEIKLLDEL 372
Cdd:COG0618   266 VSLRSKGRVDVGEIAREFGGGGHARAAGATIPGLDLEEVVEKLLEAL 312
 
Name Accession Description Interval E-value
NrnA COG0618
nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs [Nucleotide transport and ...
7-372 1.48e-41

nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs [Nucleotide transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440383 [Multi-domain]  Cd Length: 312  Bit Score: 148.03  E-value: 1.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061   7 QQVQKLFEESKYVLVVYNGKSNGDATASAIALKILLEKLKKQVDIVAAGySVPKKFHFLPQTDTIKsdisqvqkfiikld 86
Cdd:COG0618     1 EELAELLKKADRILILTHVNPDGDALGSALALALLLRALGKEVTIVYPG-EIPHELAFLPGADEIV-------------- 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061  87 vsqspietisydvrdnqlslyltpkhgiisknelRTAQSSFKYDLIITLHVSDLVSLGaafnDNADLFYKTS-ILNIDHE 165
Cdd:COG0618    66 ----------------------------------RLEDVDLEYDLVIVVDTSSPDRIG----DLAELLEKAKpVIVIDHH 107
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061 166 PNNERFGQVNLIDLTSTSVSETVYKTIKKIHsGLIDAEMATALLAGMTVATKSFRNYNITPVTLQLASELITYGADREKI 245
Cdd:COG0618   108 PSNDDFGDFNDVDPDAGATSEIIYELLKELG-IEIDPEIATALYTGIVTDTGSFRYSNTTPRDFRAAAELLEKGADLDLI 186
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1083682061 246 MENLYRTRSIAALKLWGQALSHLEHDAKHSIVWTALTRDDFTRSGSTEEDLQGIIDELIgNSPEAKTIVLIFEAADKKIT 325
Cdd:COG0618   187 ARILYPSLSLEQLKLLGRALENLEVLEDGKVAYSYLTKEDLEEFGATPDDTEGLVDYLL-SIEGVEVAVVFGEVEDGEIK 265
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1083682061 326 ALVATEKSGDALELTKKFSPQGNKKTASIQFDGLTLKEVEIKLLDEL 372
Cdd:COG0618   266 VSLRSKGRVDVGEIAREFGGGGHARAAGATIPGLDLEEVVEKLLEAL 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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