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Conserved domains on  [gi|1082307299|gb|OFW89021|]
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nucleotidyltransferase [Alphaproteobacteria bacterium RIFCSPHIGHO2_01_FULL_40_8]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NTase_sub_bind super family cl23885
Nucleotidyltransferase substrate binding protein like; Nucleotidyltransferases (EC 2.7.7) ...
 3-132 7.30e-17

Nucleotidyltransferase substrate binding protein like; Nucleotidyltransferases (EC 2.7.7) comprise a large enzyme family with diverse roles in polynucleotide synthesis and modification. This domain is structurally related to kanamycin nucleotidyltransferase (KNTase) and forms a complex with HI0073, a sequence homolog of the nucleotide-binding domain of this nucleotidyltransferase superfamily.


The actual alignment was detected with superfamily member pfam08780:

Pssm-ID: 451596  Cd Length: 126  Bit Score: 71.17  E-value: 7.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082307299   3 FEKFENSLKHLElqfeNYLALQKRDELTKIdreaIRESVIQRFEICFDSMWKLTKRYLsQISGFPDLPASPKPLLRIACD 82
Cdd:pfam08780   3 LSNLRKALASLE----EALELSRDSPLNDL----ERDGVIQRFEFTYELAWKTLKRYL-EYQGITPEAISPRDVIREAFE 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1082307299  83 NGLFRDVEKLLKYADARVATSHDYsDIKVSEAI--NLVDDFIQDAIGFYETI 132
Cdd:pfam08780  74 AGLIDDGEVWLEMLDDRNLTSHTY-DEETAREVveRIIEAYLPEFKALLTRL 124
 
Name Accession Description Interval E-value
NTase_sub_bind pfam08780
Nucleotidyltransferase substrate binding protein like; Nucleotidyltransferases (EC 2.7.7) ...
 3-132 7.30e-17

Nucleotidyltransferase substrate binding protein like; Nucleotidyltransferases (EC 2.7.7) comprise a large enzyme family with diverse roles in polynucleotide synthesis and modification. This domain is structurally related to kanamycin nucleotidyltransferase (KNTase) and forms a complex with HI0073, a sequence homolog of the nucleotide-binding domain of this nucleotidyltransferase superfamily.


Pssm-ID: 430213  Cd Length: 126  Bit Score: 71.17  E-value: 7.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082307299   3 FEKFENSLKHLElqfeNYLALQKRDELTKIdreaIRESVIQRFEICFDSMWKLTKRYLsQISGFPDLPASPKPLLRIACD 82
Cdd:pfam08780   3 LSNLRKALASLE----EALELSRDSPLNDL----ERDGVIQRFEFTYELAWKTLKRYL-EYQGITPEAISPRDVIREAFE 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1082307299  83 NGLFRDVEKLLKYADARVATSHDYsDIKVSEAI--NLVDDFIQDAIGFYETI 132
Cdd:pfam08780  74 AGLIDDGEVWLEMLDDRNLTSHTY-DEETAREVveRIIEAYLPEFKALLTRL 124
HI0074 TIGR01987
nucleotidyltransferase substrate binding protein, HI0074 family; The member of this family ...
 3-122 2.47e-11

nucleotidyltransferase substrate binding protein, HI0074 family; The member of this family from Haemophilus influenzae, HI0074, has been shown by crystal structure to resemble nucleotidyltransferase substrate binding proteins. It forms a complex with HI0073, encoded by the adjacent gene and containing a nucleotidyltransferase nucleotide binding domain (pfam01909).


Pssm-ID: 131042  Cd Length: 123  Bit Score: 56.76  E-value: 2.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082307299   3 FEKFENSLkhlelqfenyLALQKRDELTKIDREAIRESVIQRFEICFDSMWKLTKRYLSQiSGFPDLPA-SPKPLLRIAC 81
Cdd:TIGR01987   2 FESFEQAL----------MQLSDANWFDLTNDITIIDGAIQKFEFTFELAWKLMKRYLAQ-EGINDIGAySPKDVLKEAF 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1082307299  82 DNGLFRDVEKLLKYADARVATSHDYSDIKVSEAINLVDDFI 122
Cdd:TIGR01987  71 RAGLIGDESLWIAMLDDRNITSHTYDQEKAREIYAQIRDYV 111
 
Name Accession Description Interval E-value
NTase_sub_bind pfam08780
Nucleotidyltransferase substrate binding protein like; Nucleotidyltransferases (EC 2.7.7) ...
 3-132 7.30e-17

Nucleotidyltransferase substrate binding protein like; Nucleotidyltransferases (EC 2.7.7) comprise a large enzyme family with diverse roles in polynucleotide synthesis and modification. This domain is structurally related to kanamycin nucleotidyltransferase (KNTase) and forms a complex with HI0073, a sequence homolog of the nucleotide-binding domain of this nucleotidyltransferase superfamily.


Pssm-ID: 430213  Cd Length: 126  Bit Score: 71.17  E-value: 7.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082307299   3 FEKFENSLKHLElqfeNYLALQKRDELTKIdreaIRESVIQRFEICFDSMWKLTKRYLsQISGFPDLPASPKPLLRIACD 82
Cdd:pfam08780   3 LSNLRKALASLE----EALELSRDSPLNDL----ERDGVIQRFEFTYELAWKTLKRYL-EYQGITPEAISPRDVIREAFE 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1082307299  83 NGLFRDVEKLLKYADARVATSHDYsDIKVSEAI--NLVDDFIQDAIGFYETI 132
Cdd:pfam08780  74 AGLIDDGEVWLEMLDDRNLTSHTY-DEETAREVveRIIEAYLPEFKALLTRL 124
HI0074 TIGR01987
nucleotidyltransferase substrate binding protein, HI0074 family; The member of this family ...
 3-122 2.47e-11

nucleotidyltransferase substrate binding protein, HI0074 family; The member of this family from Haemophilus influenzae, HI0074, has been shown by crystal structure to resemble nucleotidyltransferase substrate binding proteins. It forms a complex with HI0073, encoded by the adjacent gene and containing a nucleotidyltransferase nucleotide binding domain (pfam01909).


Pssm-ID: 131042  Cd Length: 123  Bit Score: 56.76  E-value: 2.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1082307299   3 FEKFENSLkhlelqfenyLALQKRDELTKIDREAIRESVIQRFEICFDSMWKLTKRYLSQiSGFPDLPA-SPKPLLRIAC 81
Cdd:TIGR01987   2 FESFEQAL----------MQLSDANWFDLTNDITIIDGAIQKFEFTFELAWKLMKRYLAQ-EGINDIGAySPKDVLKEAF 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1082307299  82 DNGLFRDVEKLLKYADARVATSHDYSDIKVSEAINLVDDFI 122
Cdd:TIGR01987  71 RAGLIGDESLWIAMLDDRNITSHTYDQEKAREIYAQIRDYV 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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