|
Name |
Accession |
Description |
Interval |
E-value |
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-253 |
1.15e-149 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 417.95 E-value: 1.15e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:COG1101 1 MLELKNLSKTFNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSRVFQDPKMGTAPRMTVAENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:COG1101 81 YIGRVFQDPMMGTAPSMTIEENLALAYRRGKRRGLRRGLTKKRRELFRELLATLGLGLENRLDTKVGLLSGGQRQALSLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEKAQMT 243
Cdd:COG1101 161 MATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIILDVSGEEKKKLT 240
|
250
....*....|
gi 1080618511 244 IADYYELFEK 253
Cdd:COG1101 241 VEDLLELFEE 250
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-233 |
3.82e-54 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 174.08 E-value: 3.82e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:COG1136 1 MSPLLELRNLTKSYGTG-EGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSR----VFQDPKMgtAPRMTVAEN-LLVAKFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGG 155
Cdd:COG1136 80 LARLRRRhigfVFQFFNL--LPELTALENvALPLLLAGVSR-------KERRERARELLERVG--LGDRLDHRPSQLSGG 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHmEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG1136 149 QQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHD-PELAARADRVIRLRDGRIVSD 225
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
5-232 |
3.89e-53 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 171.16 E-value: 3.89e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAky 84
Cdd:cd03259 1 LELKGLSKTY-----GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERRN-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtAPRMTVAENLLVA-KFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:cd03259 74 IGMVFQDYAL--FPHLTVAENIAFGlKLRGVPKAEIRARVRELLELV---------GLEGLLNRYPHELSGGQQQRVALA 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03259 143 RALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQ 211
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
5-254 |
1.29e-51 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 167.93 E-value: 1.29e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKy 84
Cdd:COG1131 1 IEVRGLTKRYGD-----KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRR- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmGTAPRMTVAENL-LVAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:COG1131 75 IGYVPQEP--ALYPDLTVRENLrFFARLYGLPRKEARERIDELLELF---------GLTDAADRKVGTLSGGMKQRLGLA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEKAQMT 243
Cdd:COG1131 144 LALLHDPELLILDEPTSGLDPEARRELWELLRELAAEGK-TVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
|
250
....*....|..
gi 1080618511 244 IADYY-ELFEKE 254
Cdd:COG1131 223 LEDVFlELTGEE 234
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
5-230 |
1.59e-51 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 167.28 E-value: 1.59e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03255 1 IELKNLSKTYGGG-GEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPKMgtAPRMTVAEN-LLVAKFRGEKRgliprhlASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQA 159
Cdd:cd03255 80 RRRhigfVFQSFNL--LPDLTALENvELPLLLAGVPK-------KERRERAEELLERV--GLGDRLNHYPSELSGGQQQR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDAlKYGNRLIVMKDGHI 230
Cdd:cd03255 149 VAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGKI 218
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
3-242 |
3.82e-51 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 167.16 E-value: 3.82e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 3 AIVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA 82
Cdd:COG3638 1 PMLELRNLSKRYPGG----TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 KYLSR---VFQDPkmGTAPRMTVAENLLVAKFrGEKRGLipRHLAS--YKEEFQ---TVLAKIGngLENHIDTAVEFLSG 154
Cdd:COG3638 77 RLRRRigmIFQQF--NLVPRLSVLTNVLAGRL-GRTSTW--RSLLGlfPPEDREralEALERVG--LADKAYQRADQLSG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 155 GQRQ--ALS-LLMAtlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG3638 150 GQQQrvAIArALVQ---EPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVV 226
|
250
....*....|....*.
gi 1080618511 232 -----QDLNQEEKAQM 242
Cdd:COG3638 227 fdgppAELTDAVLREI 242
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
4-231 |
9.63e-50 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 163.68 E-value: 9.63e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:COG1120 1 MLEAENLSVGYGG-----RPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSRVFQDPkmGTAPRMTVAEnlLVAkfrgekRGLIPrHLASYKEEFQTVLAKIGN-----GLENHIDTAVEFLSGGQRQ 158
Cdd:COG1120 76 RIAYVPQEP--PAPFGLTVRE--LVA------LGRYP-HLGLFGRPSAEDREAVEEalertGLEHLADRPVDELSGGERQ 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG1120 145 RVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIV 217
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
6-230 |
3.80e-49 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 160.75 E-value: 3.80e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK-RAKy 84
Cdd:COG4619 2 ELEGLSFRVGG-----KPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEwRRQ- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGtapRMTVAENLLvakfrgekRGLIPRHLASYKEEFQTVLAKIGngLENHI-DTAVEFLSGGQRQALSLL 163
Cdd:COG4619 76 VAYVPQEPALW---GGTVRDNLP--------FPFQLRERKFDRERALELLERLG--LPPDIlDKPVERLSGGERQRLALI 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:COG4619 143 RALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-232 |
5.32e-49 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 164.50 E-value: 5.32e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:COG3842 2 AMPALELENVSKRYG-----DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RakYLSRVFQDPkmgtA--PRMTVAENllVA---KFRGEKRGLIprhlasyKEEFQTVLAKIgnGLENHIDTAVEFLSGG 155
Cdd:COG3842 77 R--NVGMVFQDY----AlfPHLTVAEN--VAfglRMRGVPKAEI-------RARVAELLELV--GLEGLADRYPHQLSGG 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 156 QRQ--ALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:COG3842 140 QQQrvALARALAP--EPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQ 216
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
6-229 |
1.55e-47 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 156.47 E-value: 1.55e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYL 85
Cdd:cd03225 1 ELKNLSFSYPDG---ARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVFQDPK---MGTaprmTVAENLLVA-KFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALS 161
Cdd:cd03225 78 GLVFQNPDdqfFGP----TVEEEVAFGlENLGLPEEEIEERVEEALELV---------GLEGLRDRSPFTLSGGQKQRVA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGH 229
Cdd:cd03225 145 IAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
25-225 |
2.72e-47 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 156.83 E-value: 2.72e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY-LSRVFQDPKmgTAPRMTVA 103
Cdd:cd03219 16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLgIGRTFQIPR--LFPELTVL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLLVAKFRGEKRGLIPRHLASYKEEFQ----TVLAKIgnGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHT 179
Cdd:cd03219 94 ENVMVAAQARTGSGLLLARARREEREAReraeELLERV--GLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPA 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1080618511 180 AALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVM 225
Cdd:cd03219 172 AGLNPEETEELAELIRE-LRERGITVLLVEHDMDVVMSLADRVTVL 216
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
4-231 |
3.61e-47 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 156.13 E-value: 3.61e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPE---K 80
Cdd:cd03257 1 LLEVKNLSVSFPTG-GGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRlrkI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDPkmGTA--PRMTVAENLlvakfrgeKRGLIPRHLASYKEEFQTVLAKIGNGLENHIDTAVEF---LSGG 155
Cdd:cd03257 80 RRKEIQMVFQDP--MSSlnPRMTIGEQI--------AEPLRIHGKLSKKEARKEAVLLLLVGVGLPEEVLNRYpheLSGG 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03257 150 QRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIV 225
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
6-233 |
3.75e-47 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 156.57 E-value: 3.75e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYL 85
Cdd:cd03256 2 EVENLSKTYPNG----KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SR---VFQDPKMgtAPRMTVAENLLVAKFrGEK---RGLIPRHLASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQA 159
Cdd:cd03256 78 RQigmIFQQFNL--IERLSVLENVLSGRL-GRRstwRSLFGLFPKEEKQRALAALERVG--LLDKAYQRADQLSGGQQQR 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03256 153 VAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFD 226
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
5-233 |
2.11e-46 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 154.41 E-value: 2.11e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:COG1122 1 IELENLSFSYPGG----TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPK----MgtaprMTVAENllVAkFrgekrGliPRHLASYKEE----FQTVLAKIGngLENHIDTAVEFLSGGQ 156
Cdd:COG1122 77 VGLVFQNPDdqlfA-----PTVEED--VA-F-----G--PENLGLPREEirerVEEALELVG--LEHLADRPPHELSGGQ 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 157 RQ--ALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG1122 140 KQrvAIAGVLAM--EPEVLVLDEPTAGLDPRGRRELLELLKRLNKEG-KTVIIVTHDLDLVAELADRVIVLDDGRIVAD 215
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-225 |
1.03e-45 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 153.27 E-value: 1.03e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTK---AVsngmneekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYS 77
Cdd:COG0411 1 SDPLLEVRGLTKrfgGL--------VAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEKRAKY-LSRVFQDPKMgtAPRMTVAENLLVAKFRGEKRGLI------PRHLASYKEEFQTV---LAKIgnGLENHIDT 147
Cdd:COG0411 73 PHRIARLgIARTFQNPRL--FPELTVLENVLVAAHARLGRGLLaallrlPRARREEREARERAeelLERV--GLADRADE 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 148 AVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVM 225
Cdd:COG0411 149 PAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVL 226
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
6-233 |
1.22e-44 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 148.35 E-value: 1.22e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYL 85
Cdd:cd03214 1 EVENLSVGYGG-----RTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVFQdpkmgtaprmtvaenllvakfrgekrgliprhlasykeefqtVLAKIgnGLENHIDTAVEFLSGGQRQALSLLMA 165
Cdd:cd03214 76 AYVPQ------------------------------------------ALELL--GLAHLADRPFNELSGGERQRVLLARA 111
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 166 TLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03214 112 LAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQ 179
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
5-230 |
8.84e-44 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 145.62 E-value: 8.84e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRaKY 84
Cdd:cd03230 1 IEVRNLSKRYGK-----KTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVK-RR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmGTAPRMTVAENLLvakfrgekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALSLLM 164
Cdd:cd03230 75 IGYLPEEP--SLYENLTVRENLK--------------------------------------------LSGGMKQRLALAQ 108
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:cd03230 109 ALLHDPELLILDEPTSGLDPESRREFWELLRELKKEGK-TILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
2-231 |
4.57e-43 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 152.75 E-value: 4.57e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:COG1123 258 EPLLEVRNLSKRYPVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSL 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYLSR---VFQDPKMGTAPRMTVAENLLvakfrgekRGLIPRHLASYKEEFQTV---LAKIgnGL-ENHIDTAVEFLSG 154
Cdd:COG1123 338 RELRRRvqmVFQDPYSSLNPRMTVGDIIA--------EPLRLHGLLSRAERRERVaelLERV--GLpPDLADRYPHELSG 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG1123 408 GQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIV 484
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
5-234 |
9.28e-43 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 144.54 E-value: 9.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEkraky 84
Cdd:cd03293 1 LEVRNVSKTYGGG-GGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD----- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmGTAPRMTVAEN-LLVAKFRGEKRGLIprhlasyKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLL 163
Cdd:cd03293 75 RGYVFQQD--ALLPWLTVLDNvALGLELQGVPKAEA-------RERAEELLELVG--LSGFENAYPHQLSGGMRQRVALA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVM--KDGHIVQDL 234
Cdd:cd03293 144 RALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLsaRPGRIVAEV 216
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
4-233 |
2.66e-42 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 143.65 E-value: 2.66e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAk 83
Cdd:COG2884 1 MIRFENVSKRYPGG----REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIP- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR----VFQDPKMgtAPRMTVAENL-LVAKFRGEKRGLIprhlasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQ 158
Cdd:COG2884 76 YLRRrigvVFQDFRL--LPDRTVYENVaLPLRVTGKSRKEI-------RRRVREVLDLV--GLSDKAKALPHELSGGEQQ 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG2884 145 RVAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGT-TVLIATHDLELVDRMPKRVLELEDGRLVRD 218
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
24-231 |
3.12e-42 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 143.34 E-value: 3.12e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY-LSRVFQDpkMGTAPRMTV 102
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYVPEG--RRIFPELTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 103 AENLLVAKFRGEKRGlIPRHLASYKEEFqTVLAKIgnglenhIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAAL 182
Cdd:cd03224 93 EENLLLGAYARRRAK-RKARLERVYELF-PRLKER-------RKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGL 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1080618511 183 DPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03224 164 APKIVEEIFEAIRE-LRDEGVTILLVEQNARFALEIADRAYVLERGRVV 211
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-230 |
5.57e-42 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 143.31 E-value: 5.57e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTkaVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnyspEK 80
Cdd:COG1121 3 MMPAIELENLT--VSYG---GRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPR----RA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAK--YLsrvfqdPKMGTAPR---MTVAEnlLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIgnGLENHIDTAVEFLSGG 155
Cdd:COG1121 74 RRRigYV------PQRAEVDWdfpITVRD--VVLMGRYGRRGLFRRPSRADREAVDEALERV--GLEDLADRPIGELSGG 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:COG1121 144 QQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREG-KTILVVTHDLGAVREYFDRVLLLNRGLV 217
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-238 |
6.09e-42 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 149.67 E-value: 6.09e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS---SGKIYILGEDVTNYS 77
Cdd:COG1123 1 MTPLLEVRDLSVRYPGG---DVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEKRAKYLSRVFQDPKMGTAPrMTVAENLLvakfRGEKRGLIPRHLAsyKEEFQTVLAKIGngLENHIDTAVEFLSGGQR 157
Cdd:COG1123 78 EALRGRRIGMVFQDPMTQLNP-VTVGDQIA----EALENLGLSRAEA--RARVLELLEAVG--LERRLDRYPHQLSGGQR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQE 237
Cdd:COG1123 149 QRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPE 228
|
.
gi 1080618511 238 E 238
Cdd:COG1123 229 E 229
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
25-238 |
1.08e-41 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 142.47 E-value: 1.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKylSRVFQDPKMgtAPRMTVAE 104
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKRDI--SYVPQNYAL--FPHMTVYK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLLVA-KFRGEKRGLIPRHLasykEEFQTVLakignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALD 183
Cdd:cd03299 91 NIAYGlKKRKVDKKEIERKV----LEIAEML-----GIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALD 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 184 PKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:cd03299 162 VRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEE 216
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
5-229 |
1.44e-41 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 139.83 E-value: 1.44e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03228 1 IEFKNVSFSYPGRPKP---VLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtaPRMTVAENLlvakfrgekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALSLLM 164
Cdd:cd03228 78 IAYVPQDPFL---FSGTIRENI---------------------------------------------LSGGQRQRIAIAR 109
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvkQDALTALMITHHMEdALKYGNRLIVMKDGH 229
Cdd:cd03228 110 ALLRDPPILILDEATSALDPETEALILEALRAL--AKGKTVIVIAHRLS-TIRDADRIIVLDDGR 171
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
4-233 |
5.00e-41 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 140.90 E-value: 5.00e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:TIGR02315 1 MLEVENLSKVYPNG----KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR---VFQDPKMgtAPRMTVAENLLVAKFRGEK--RGLIPRHLASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQ 158
Cdd:TIGR02315 77 LRRRigmIFQHYNL--IERLTVLENVLHGRLGYKPtwRSLLGRFSEEDKERALSALERVG--LADKAYQRADQLSGGQQQ 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:TIGR02315 153 RVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFD 227
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-238 |
8.70e-41 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 140.11 E-value: 8.70e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:COG1127 2 SEPMIEVRNLTKSF-----GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSR---VFQDPKMGTAprMTVAENllVAkFRGEKRGLIPRhlasyKEEFQTVLAKIGN-GLENHIDTAVEFLSGGQ 156
Cdd:COG1127 77 LYELRRRigmLFQGGALFDS--LTVFEN--VA-FPLREHTDLSE-----AEIRELVLEKLELvGLPGAADKMPSELSGGM 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQ------ALSLlmatlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:COG1127 147 RKrvalarALAL------DPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKI 220
|
....*...
gi 1080618511 231 VQDLNQEE 238
Cdd:COG1127 221 IAEGTPEE 228
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-235 |
1.49e-40 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 140.22 E-value: 1.49e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEk 80
Cdd:COG1116 4 AAPALELRGVSKRFPTG-GGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAkYlsrVFQDPkmgtA--PRMTVAEN-LLVAKFRGEKRgliprhlASYKEEFQTVLAKIG-NGLENHidtaveF---LS 153
Cdd:COG1116 82 RG-V---VFQEP----AllPWLTVLDNvALGLELRGVPK-------AERRERARELLELVGlAGFEDA------YphqLS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 154 GGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKD--GHIV 231
Cdd:COG1116 141 GGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVLSArpGRIV 220
|
....
gi 1080618511 232 QDLN 235
Cdd:COG1116 221 EEID 224
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
5-229 |
2.82e-40 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 136.93 E-value: 2.82e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYS---PEKR 81
Cdd:cd03229 1 LELKNVSKRYG-----QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEdelPPLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKyLSRVFQDPkmGTAPRMTVAENLLVAkfrgekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALS 161
Cdd:cd03229 76 RR-IGMVFQDF--ALFPHLTVLENIALG------------------------------------------LSGGQQQRVA 110
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGH 229
Cdd:cd03229 111 LARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
6-229 |
6.90e-40 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 135.45 E-value: 6.90e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYL 85
Cdd:cd00267 1 EIENLSFRY-----GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVFQdpkmgtaprmtvaenllvakfrgekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALSLLMA 165
Cdd:cd00267 76 GYVPQ-------------------------------------------------------------LSGGQRQRVALARA 94
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 166 TLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGH 229
Cdd:cd00267 95 LLLNPDLLLLDEPTSGLDPASRERLLELLRELAEEGR-TVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
29-233 |
1.79e-39 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 136.42 E-value: 1.79e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 29 SLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAkyLSRVFQDPKMgtAPRMTVAENLLV 108
Cdd:COG3840 19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERP--VSMLFQENNL--FPHLTVAQNIGL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 109 akfrgekrGLIPR-HL-ASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQ--ALS--LLMatlKRPeLLLLDEHTAAL 182
Cdd:COG3840 95 --------GLRPGlKLtAEQRAQVEQALERVG--LAGLLDRLPGQLSGGQRQrvALArcLVR---KRP-ILLLDEPFSAL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 183 DPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG3840 161 DPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAAD 211
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
5-247 |
4.61e-39 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 136.09 E-value: 4.61e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:COG1124 2 LEVRNLSVSYGQG-GRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkMGTA-PRMTV----AENLLVAKFRGEKR---------GLIPRHLASYKEEfqtvlakignglenhidtave 150
Cdd:COG1124 81 VQMVFQDP-YASLhPRHTVdrilAEPLRIHGLPDREEriaelleqvGLPPSFLDRYPHQ--------------------- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 151 fLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:COG1124 139 -LSGGQRQRVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRI 217
|
250
....*....|....*..
gi 1080618511 231 VQDLNQEEKAQMTIADY 247
Cdd:COG1124 218 VEELTVADLLAGPKHPY 234
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
29-233 |
8.50e-39 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 134.71 E-value: 8.50e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 29 SLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAkyLSRVFQDPKMgtAPRMTVAENLLV 108
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRP--VSMLFQENNL--FSHLTVAQNIGL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 109 akfrgekrGLIP--RHLASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKT 186
Cdd:PRK10771 95 --------GLNPglKLNAAQREKLHAIARQMG--IEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPAL 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1080618511 187 SQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:PRK10771 165 RQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWD 211
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
19-252 |
9.22e-39 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 141.83 E-value: 9.22e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 19 NEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAp 98
Cdd:COG4987 345 GAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRIAVVPQRPHLFDT- 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 rmTVAENLLVAKfrgekrgliPRhlASyKEEFQTVLAKIG---------NGLENHIDTAVEFLSGGQRQALSLLMATLKR 169
Cdd:COG4987 424 --TLRENLRLAR---------PD--AT-DEELWAALERVGlgdwlaalpDGLDTWLGEGGRRLSGGERRRLALARALLRD 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 170 PELLLLDEHTAALDPKTSQALMTLTDEFVKQDALtaLMITHHMEdALKYGNRLIVMKDGHIVQDLNQEEKAQmTIADYYE 249
Cdd:COG4987 490 APILLLDEPTEGLDAATEQALLADLLEALAGRTV--LLITHRLA-GLERMDRILVLEDGRIVEQGTHEELLA-QNGRYRQ 565
|
...
gi 1080618511 250 LFE 252
Cdd:COG4987 566 LYQ 568
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
5-232 |
1.12e-38 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 133.92 E-value: 1.12e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAky 84
Cdd:cd03301 1 VELENVTKRF-----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRD-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDpkMGTAPRMTVAENLLVA-KFRGEKRGLIPRHLASykeefqtvLAKIgNGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:cd03301 74 IAMVFQN--YALYPHMTVYDNIAFGlKLRKVPKDEIDERVRE--------VAEL-LQIEHLLDRKPKQLSGGQRQRVALG 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03301 143 RAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQ 211
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
3-232 |
1.33e-38 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 137.51 E-value: 1.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 3 AIVELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA 82
Cdd:COG3839 2 ASLELENVSKSYGG-----VEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDRN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 kyLSRVFQDPkmgtA--PRMTVAENLLVA-KFRGEKRGLIprhlasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQA 159
Cdd:COG3839 77 --IAMVFQSY----AlyPHMTVYENIAFPlKLRKVPKAEI-------DRRVREAAELL--GLEDLLDRKPKQLSGGQRQR 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:COG3839 142 VALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQ 214
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
6-231 |
2.05e-38 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 133.43 E-value: 2.05e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpeKRAKYL 85
Cdd:cd03235 1 EVEDLTVSYGG-----HPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER--KRIGYV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVFQ-DPkmgTAPrMTVAEnlLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALSLLM 164
Cdd:cd03235 74 PQRRSiDR---DFP-ISVRD--VVLMGLYGHKGLFRRLSKADKAKVDEALERV--GLSELADRQIGELSGGQQQRVLLAR 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMkDGHIV 231
Cdd:cd03235 146 ALVQDPDLLLLDEPFAGVDPKTQEDIYELLRE-LRREGMTILVVTHDLGLVLEYFDRVLLL-NRTVV 210
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
6-251 |
2.70e-38 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 133.83 E-value: 2.70e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKyL 85
Cdd:COG4555 3 EVENLSKKYGK-----VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQ-I 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVFQDPkmGTAPRMTVAENL-LVAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALSLLM 164
Cdd:COG4555 77 GVLPDER--GLYDRLTVRENIrYFAELYGLFDEELKKRIEELIELL---------GLEEFLDRRVGELSTGMKKKVALAR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMtltdEFVKQDA---LTALMITHHMEDALKYGNRLIVMKDGHIV-QDLNQEEKA 240
Cdd:COG4555 146 ALVHDPKVLLLDEPTNGLDVMARRLLR----EILRALKkegKTVLFSSHIMQEVEALCDRVVILHKGKVVaQGSLDELRE 221
|
250
....*....|.
gi 1080618511 241 QMTIADYYELF 251
Cdd:COG4555 222 EIGEENLEDAF 232
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
5-228 |
3.31e-38 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 133.01 E-value: 3.31e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNeekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtNYSPEKRAKY 84
Cdd:cd03263 1 LQIRNLTKTYKKGTK---PAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSI-RTDRKAARQS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmGTAPRMTVAENL-LVAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:cd03263 77 LGYCPQFD--ALFDELTVREHLrFYARLKGLPKSEIKEEVELLLRVL---------GLTDKANKRARTLSGGMKRKLSLA 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:cd03263 146 IALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDG 208
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
5-232 |
4.84e-38 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 132.75 E-value: 4.84e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAky 84
Cdd:cd03300 1 IELENVSKFYGG-----FVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKRP-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQdpKMGTAPRMTVAENllVA---KFRGEKRGLIprhlasyKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALS 161
Cdd:cd03300 74 VNTVFQ--NYALFPHLTVFEN--IAfglRLKKLPKAEI-------KERVAEALDLVQ--LEGYANRKPSQLSGGQQQRVA 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03300 141 IARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQ 211
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
5-232 |
1.61e-37 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 138.35 E-value: 1.61e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTkaVSNGmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:COG4988 337 IELEDVS--FSYP--GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQ 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtaPRMTVAENLLVAkfrgekrglipRHLASyKEEFQTVLAKIG-----NGLENHIDTAVEF----LSGG 155
Cdd:COG4988 413 IAWVPQNPYL---FAGTIRENLRLG-----------RPDAS-DEELEAALEAAGldefvAALPDGLDTPLGEggrgLSGG 477
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDaLKYGNRLIVMKDGHIVQ 232
Cdd:COG4988 478 QAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKG--RTVILITHRLAL-LAQADRILVLDDGRIVE 551
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
5-231 |
4.21e-37 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 130.70 E-value: 4.21e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03261 1 IELRGLTKSF-----GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR---VFQDPKMGTAprMTVAENllVAKFRGEKRGLiprhlaSYKEEFQTVLAKIGN-GLENHIDTAVEFLSGGQRQAL 160
Cdd:cd03261 76 RRRmgmLFQSGALFDS--LTVFEN--VAFPLREHTRL------SEEEIREIVLEKLEAvGLRGAEDLYPAELSGGMKKRV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTS----QALMTLTDEFvkqdALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03261 146 ALARALALDPELLLYDEPTAGLDPIASgvidDLIRSLKKEL----GLTSIMVTHDLDTAFAIADRIAVLYDGKIV 216
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
5-233 |
8.36e-37 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 130.63 E-value: 8.36e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNyspEKRAKY 84
Cdd:TIGR04520 1 IEVENVSFSYPE---SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLD---EENLWE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPK---MGTaprmTVAENllVAkFRGEKRGlIPRhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQR 157
Cdd:TIGR04520 75 IRKkvgmVFQNPDnqfVGA----TVEDD--VA-FGLENLG-VPR--EEMRKRVDEALKLVG--MEDFRDREPHLLSGGQK 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 158 Q--ALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKyGNRLIVMKDGHIVQD 233
Cdd:TIGR04520 143 QrvAIAGVLAM--RPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAE 217
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
5-232 |
1.17e-36 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 129.73 E-value: 1.17e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03295 1 IEFENVTKRYGGG----KKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQdpKMGTAPRMTVAENL-LVAKFRGEKRgliprhlASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:cd03295 77 IGYVIQ--QIGLFPHMTVEENIaLVPKLLKWPK-------EKIRERADELLALVGLDPAEFADRYPHELSGGQQQRVGVA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMtltDEFVK-QDAL--TALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03295 148 RALAADPPLLLMDEPFGALDPITRDQLQ---EEFKRlQQELgkTIVFVTHDIDEAFRLADRIAIMKNGEIVQ 216
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
24-231 |
1.19e-36 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 129.33 E-value: 1.19e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK----YLS---RVFqdpkmgt 96
Cdd:COG0410 18 VLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARlgigYVPegrRIF------- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 aPRMTVAENLLVAKFRGEKRGLIPRHLAS-YK-----EEFQTVLAkiGNglenhidtavefLSGGQRQALSL---LMAtl 167
Cdd:COG0410 91 -PSLTVEENLLLGAYARRDRAEVRADLERvYElfprlKERRRQRA--GT------------LSGGEQQMLAIgraLMS-- 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 168 kRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG0410 154 -RPKLLLLDEPSLGLAPLIVEEIFEIIRR-LNREGVTILLVEQNARFALEIADRAYVLERGRIV 215
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-233 |
1.71e-36 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 132.38 E-value: 1.71e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:PRK09452 12 SPLVELRGISKSF-----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAENR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 akYLSRVFQDPKMgtAPRMTVAENllVA-KFRGEKRG---LIPRhlasYKEEFQTVlakignGLENHIDTAVEFLSGGQR 157
Cdd:PRK09452 87 --HVNTVFQSYAL--FPHMTVFEN--VAfGLRMQKTPaaeITPR----VMEALRMV------QLEEFAQRKPHQLSGGQQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:PRK09452 151 QRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQD 226
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
3-211 |
8.56e-36 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 126.44 E-value: 8.56e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 3 AIVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNySPEKRA 82
Cdd:COG4133 1 MMLEAENLSCRR-----GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRD-AREDYR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 KYLSRVFQDPkmGTAPRMTVAENL-LVAKFRGEKRGliprhlasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALS 161
Cdd:COG4133 75 RRLAYLGHAD--GLKPELTVRENLrFWAALYGLRAD---------REAIDEALEAV--GLAGLADLPVRQLSAGQKRRVA 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALtALMITHH 211
Cdd:COG4133 142 LARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLARGGA-VLLTTHQ 190
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
5-254 |
1.02e-35 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 134.19 E-value: 1.02e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:COG2274 474 IELENVSFRYPG---DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQ 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKM--GTaprmtVAENLLVAkfrgekrglipRHLASYkEEFQTVLAKIG---------NGLENHIDTAVEFLS 153
Cdd:COG2274 551 IGVVLQDVFLfsGT-----IRENITLG-----------DPDATD-EEIIEAARLAGlhdfiealpMGYDTVVGEGGSNLS 613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 154 GGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEdALKYGNRLIVMKDGHIVQD 233
Cdd:COG2274 614 GGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKG--RTVIIIAHRLS-TIRLADRIIVLDKGRIVED 690
|
250 260
....*....|....*....|.
gi 1080618511 234 LNQEEKAQmTIADYYELFEKE 254
Cdd:COG2274 691 GTHEELLA-RKGLYAELVQQQ 710
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
5-233 |
7.86e-35 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 125.64 E-value: 7.86e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNySPEKRAKY 84
Cdd:TIGR04521 1 IKLKNVSYIYQPGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITA-KKKKKLKD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPkmgtaprmtvaENLL----VAK---FrgekrGliPRHLASYKEEF----QTVLAKIGngLENHIDTAV 149
Cdd:TIGR04521 80 LRKkvglVFQFP-----------EHQLfeetVYKdiaF-----G--PKNLGLSEEEAeervKEALELVG--LDEEYLERS 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 150 EF-LSGGQ--RQALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMK 226
Cdd:TIGR04521 140 PFeLSGGQmrRVAIAGVLAM--EPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMH 217
|
....*..
gi 1080618511 227 DGHIVQD 233
Cdd:TIGR04521 218 KGKIVLD 224
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
5-233 |
4.62e-34 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 121.92 E-value: 4.62e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMneekvILDDVSLEIrEHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK- 83
Cdd:cd03264 1 LQLENLTKRYGKKR-----ALDGVSLTL-GPGMYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRi 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 -YLSrvfQDPkmGTAPRMTVAENLlvaKFRGEKRGLIPRHLasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALSL 162
Cdd:cd03264 75 gYLP---QEF--GVYPNFTVREFL---DYIAWLKGIPSKEV---KARVDEVLELV--NLGDRAKKKIGSLSGGMRRRVGI 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 163 LMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03264 142 AQALVGDPSILIVDEPTAGLDPEERIRFRNLLSE-LGEDR-IVILSTHIVEDVESLCNQVAVLNKGKLVFE 210
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-235 |
1.35e-33 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 122.28 E-value: 1.35e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIvELKNVTkAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEk 80
Cdd:COG4525 1 MSML-TVRHVS-VRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGAD- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKylsrVFQdpKMGTAPRMTVAENllVA---KFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQR 157
Cdd:COG4525 78 RGV----VFQ--KDALLPWLNVLDN--VAfglRLRGVPK-------AERRARAEELLALVG--LADFARRRIWQLSGGMR 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKD--GHIVQDLN 235
Cdd:COG4525 141 QRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMSPgpGRIVERLE 220
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-238 |
1.97e-33 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 126.29 E-value: 1.97e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTK---AVsngmneeKViLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYS 77
Cdd:COG1129 1 AEPLLEMRGISKsfgGV-------KA-LDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRS 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 P-EKRAKYLSRVFQDPKMgtAPRMTVAENLLVAKFRGeKRGLIPRhlASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQ 156
Cdd:COG1129 73 PrDAQAAGIAIIHQELNL--VPNLSVAENIFLGREPR-RGGLIDW--RAMRRRARELLARL--GLDIDPDTPVGDLSVAQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIV----- 231
Cdd:COG1129 146 QQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVgtgpv 224
|
....*..
gi 1080618511 232 QDLNQEE 238
Cdd:COG1129 225 AELTEDE 231
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
5-232 |
1.74e-32 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 121.41 E-value: 1.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDV-TNYSPEKRak 83
Cdd:COG1118 3 IEVRNISKRFGS-----FTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRER-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 ylsR---VFQDPkmgtA--PRMTVAENllVAkFrgekrGLipRHLASYKEEFQTV----LAKIG-NGLENHidtaveF-- 151
Cdd:COG1118 76 ---RvgfVFQHY----AlfPHMTVAEN--IA-F-----GL--RVRPPSKAEIRARveelLELVQlEGLADR------Yps 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 152 -LSGGQRQ--ALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:COG1118 133 qLSGGQRQrvALARALAV--EPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQG 210
|
....
gi 1080618511 229 HIVQ 232
Cdd:COG1118 211 RIEQ 214
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
5-231 |
1.80e-32 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 116.37 E-value: 1.80e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP-EKRAK 83
Cdd:cd03216 1 LELRGITKRFGGV-----KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPrDARRA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSRVFQdpkmgtaprmtvaenllvakfrgekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALSLL 163
Cdd:cd03216 76 GIAMVYQ-------------------------------------------------------------LSVGERQMVEIA 94
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03216 95 RALARNARLLILDEPTAALTPAEVERLFKVIRRL-RAQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
27-232 |
3.65e-32 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 118.51 E-value: 3.65e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 27 DVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP----EKRAKYLSRVFQdpKMGTAPRMTV 102
Cdd:cd03294 42 DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRkelrELRRKKISMVFQ--SFALLPHRTV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 103 AENllvAKFRGEKRGlIPRhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAAL 182
Cdd:cd03294 120 LEN---VAFGLEVQG-VPR--AEREERAAEALELVG--LEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSAL 191
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 183 DP---KTSQ-ALMTLTDEFVKqdalTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03294 192 DPlirREMQdELLRLQAELQK----TIVFITHDLDEALRLGDRIAIMKDGRLVQ 241
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
5-230 |
4.59e-32 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 116.86 E-value: 4.59e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA-- 82
Cdd:cd03262 1 IEIKNLHKSFGD-----FHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINElr 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 KYLSRVFQDPKMgtAPRMTVAENLLVA--KFRGEKRgliprhlASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQ-- 158
Cdd:cd03262 76 QKVGMVFQQFNL--FPHLTVLENITLApiKVKGMSK-------AEAEERALELLEKV--GLADKADAYPAQLSGGQQQrv 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 159 --ALSLLMatlkRPELLLLDEHTAALDPKTSQ-ALMTLTDefVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:cd03262 145 aiARALAM----NPKVMLFDEPTSALDPELVGeVLDVMKD--LAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-233 |
4.86e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 118.65 E-value: 4.86e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVT-KAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTN---- 75
Cdd:PRK13633 1 MNEMIKCKNVSyKYESNEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDeenl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 76 YSPEKRAkylSRVFQDPkmgtaprmtvaENLLVAKFRGEKRGLIPRHLASYKEEFQT----VLAKIgnGLENHIDTAVEF 151
Cdd:PRK13633 81 WDIRNKA---GMVFQNP-----------DNQIVATIVEEDVAFGPENLGIPPEEIRErvdeSLKKV--GMYEYRRHAPHL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 152 LSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKyGNRLIVMKDGHIV 231
Cdd:PRK13633 145 LSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVV 223
|
..
gi 1080618511 232 QD 233
Cdd:PRK13633 224 ME 225
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
5-232 |
1.59e-31 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 116.28 E-value: 1.59e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAky 84
Cdd:cd03296 3 IEVRNVSKRFGDF-----VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERN-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtAPRMTVAENllVAkFrgekrGLIPRHLASYKEEfQTVLAKIGN-----GLENHIDTAVEFLSGGQRQA 159
Cdd:cd03296 76 VGFVFQHYAL--FRHMTVFDN--VA-F-----GLRVKPRSERPPE-AEIRAKVHEllklvQLDWLADRYPAQLSGGQRQR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03296 145 VALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQ 217
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
27-233 |
1.84e-31 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 115.28 E-value: 1.84e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 27 DVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAkyLSRVFQDPKMgtAPRMTVAENL 106
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRP--VSMLFQENNL--FAHLTVEQNV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 107 LVakfrgekrGLIPR-HL-ASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDP 184
Cdd:cd03298 92 GL--------GLSPGlKLtAEDRQAIEVALARVG--LAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDP 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1080618511 185 KTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03298 162 ALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQ 210
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
25-180 |
2.67e-31 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 112.74 E-value: 2.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGtaPRMTVAE 104
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLF--PRLTVRE 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 105 NLlvaKFRGEKRGLIPRHlasYKEEFQTVLAKIGNG--LENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTA 180
Cdd:pfam00005 79 NL---RLGLLLKGLSKRE---KDARAEEALEKLGLGdlADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
2-233 |
2.82e-31 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 115.57 E-value: 2.82e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTkaVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGK-IYILGEDVTNYS-PE 79
Cdd:COG1119 1 DPLLELRNVT--VRRG---GKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdVRLFGERRGGEDvWE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAK--YLSRVFQDPkmgTAPRMTVAENLLVAKFrgekrGLIPRHLASYKEEFQTVLAKIGN-GLENHIDTAVEFLSGGQ 156
Cdd:COG1119 76 LRKRigLVSPALQLR---FPRDETVLDVVLSGFF-----DSIGLYREPTDEQRERARELLELlGLAHLADRPFGTLSQGE 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG1119 148 QRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAA 224
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
5-231 |
5.71e-31 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 113.91 E-value: 5.71e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVT-------NYS 77
Cdd:cd03269 1 LEVENVTKRFG-----RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDiaarnriGYL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEKRAKYlsrvfqdpkmgtaPRMTVAENLL-VAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQ 156
Cdd:cd03269 76 PEERGLY-------------PKMKVIDQLVyLAQLKGLKKEEARRRIDEWLERL---------ELSEYANKRVEELSKGN 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03269 134 QQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIREL-ARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
4-231 |
5.97e-31 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 114.60 E-value: 5.97e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGMNEEKViLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:cd03258 1 MIELKNVSKVFGDTGGKVTA-LKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR---VFQDPKMGTAPrmTVAEN----LLVAKFRGEKRGLIPRHLasykeefqtvLAKIGngLENHIDTAVEFLSGGQ 156
Cdd:cd03258 80 ARRRigmIFQHFNLLSSR--TVFENvalpLEIAGVPKAEIEERVLEL----------LELVG--LEDKADAYPAQLSGGQ 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03258 146 KQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVV 220
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
5-232 |
6.92e-31 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 119.88 E-value: 6.92e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVtkavSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:COG1132 340 IEFENV----SFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQ 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTaprMTVAENLLVAKFRgekrgliprhlASyKEEFQTVLAKIG-----NGLENHIDTAVE----FLSGG 155
Cdd:COG1132 416 IGVVPQDTFLFS---GTIRENIRYGRPD-----------AT-DEEVEEAAKAAQahefiEALPDGYDTVVGergvNLSGG 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALmtltdefvkQDAL-------TALMITHHM---EDAlkygNRLIVM 225
Cdd:COG1132 481 QRQRIAIARALLKDPPILILDEATSALDTETEALI---------QEALerlmkgrTTIVIAHRLstiRNA----DRILVL 547
|
....*..
gi 1080618511 226 KDGHIVQ 232
Cdd:COG1132 548 DDGRIVE 554
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
6-222 |
8.77e-31 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 113.35 E-value: 8.77e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTkaVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP---VSSGKIYILGEDVTNYSPEKRA 82
Cdd:COG4136 3 SLENLT--ITLG---GRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSpafSASGEVLLNGRRLTALPAEQRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 kyLSRVFQDPKMgtAPRMTVAENLLVA---KFRGEKRgliprhlasyKEEFQTVLAKIG-NGLENH-IDTavefLSGGQR 157
Cdd:COG4136 78 --IGILFQDDLL--FPHLSVGENLAFAlppTIGRAQR----------RARVEQALEEAGlAGFADRdPAT----LSGGQR 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRL 222
Cdd:COG4136 140 ARVALLRALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAAGRVL 204
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
5-238 |
2.27e-30 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 112.70 E-value: 2.27e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVtkavSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03254 3 IEFENV----NFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmgTAPRMTVAENLLVAKFRGEKRGLIprhLASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLM 164
Cdd:cd03254 79 IGVVLQDT---FLFSGTIMENIRLGRPNATDEEVI---EAAKEAGAHDFIMKLPNGYDTVLGENGGNLSQGERQLLAIAR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALmtltdefvkQDAL-------TALMITHHMeDALKYGNRLIVMKDGHIVQDLNQE 237
Cdd:cd03254 153 AMLRDPKILILDEATSNIDTETEKLI---------QEALeklmkgrTSIIIAHRL-STIKNADKILVLDDGKIIEEGTHD 222
|
.
gi 1080618511 238 E 238
Cdd:cd03254 223 E 223
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
24-244 |
6.74e-30 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 111.46 E-value: 6.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKylsrvfqdpkMGTA------ 97
Cdd:TIGR03410 15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERAR----------AGIAyvpqgr 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 98 ---PRMTVAENLLV--AKFRGEKRGlIPRHLASYKEEFQTVLAKIGnGLenhidtavefLSGGQRQALSLLMATLKRPEL 172
Cdd:TIGR03410 85 eifPRLTVEENLLTglAALPRRSRK-IPDEIYELFPVLKEMLGRRG-GD----------LSGGQQQQLAIARALVTRPKL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 173 LLLDEHTAALDP----KTSQALMTLTDEfvkqDALTALMITHHMEDALKYGNRLIVMKDGHIVQ-----DLNQEE-KAQM 242
Cdd:TIGR03410 153 LLLDEPTEGIQPsiikDIGRVIRRLRAE----GGMAILLVEQYLDFARELADRYYVMERGRVVAsgagdELDEDKvRRYL 228
|
..
gi 1080618511 243 TI 244
Cdd:TIGR03410 229 AV 230
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-231 |
7.23e-30 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 113.61 E-value: 7.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTkaVSNGMNEEKV-ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP---VSSGKIYILGEDVTNYSPE 79
Cdd:COG0444 1 LLEVRNLK--VYFPTRRGVVkAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKYLSR----VFQDPkMgTA--PRMTV----AENLLVakFRGEKRgliprhlASYKEEFQTVLAKIGnglenhIDTAV 149
Cdd:COG0444 79 ELRKIRGReiqmIFQDP-M-TSlnPVMTVgdqiAEPLRI--HGGLSK-------AEARERAIELLERVG------LPDPE 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 150 EF-------LSGGQRQALSLLMATLKRPELLLLDEHTAALDPkTSQA-----LMTLTDEFVkqdaLTALMITHHMEDALK 217
Cdd:COG0444 142 RRldrypheLSGGMRQRVMIARALALEPKLLIADEPTTALDV-TIQAqilnlLKDLQRELG----LAILFITHDLGVVAE 216
|
250
....*....|....
gi 1080618511 218 YGNRLIVMKDGHIV 231
Cdd:COG0444 217 IADRVAVMYAGRIV 230
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-242 |
7.34e-30 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 116.28 E-value: 7.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTK---AVsngmneekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYS 77
Cdd:COG3845 2 MPPALELRGITKrfgGV--------VANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEK-RAKYLSRVFQDPKMgtAPRMTVAENLLVAkfrGEKRGLIPRHLASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQ 156
Cdd:COG3845 74 PRDaIALGIGMVHQHFML--VPNLTVAENIVLG---LEPTKGGRLDRKAARARIRELSERY--GLDVDPDAKVEDLSVGE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHIV----- 231
Cdd:COG3845 147 QQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAEG-KSIIFITHKLREVMAIADRVTVLRRGKVVgtvdt 225
|
250
....*....|.
gi 1080618511 232 QDLNQEEKAQM 242
Cdd:COG3845 226 AETSEEELAEL 236
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
5-231 |
9.87e-30 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 111.71 E-value: 9.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:COG4604 2 IEIKNVSKRYGG-----KVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmGTAPRMTVAEnlLVAkFrgekrGLIPRHlasykeefQTVLAKIGnglENHIDTAVEF------------- 151
Cdd:COG4604 77 LAILRQEN--HINSRLTVRE--LVA-F-----GRFPYS--------KGRLTAED---REIIDEAIAYldledladrylde 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 152 LSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALM----TLTDEFVKqdalTALMITHHMEDALKYGNRLIVMKD 227
Cdd:COG4604 136 LSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMkllrRLADELGK----TVVIVLHDINFASCYADHIVAMKD 211
|
....
gi 1080618511 228 GHIV 231
Cdd:COG4604 212 GRVV 215
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
22-233 |
1.12e-29 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 111.79 E-value: 1.12e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMgTAPrMT 101
Cdd:PRK13548 15 RTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVLPQHSSL-SFP-FT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 VAEnlLVAkfrgekRGLIPrHLASYKEE---FQTVLAKIG-NGLENHIDTAvefLSGGQRQ------ALSLLMATLKRPE 171
Cdd:PRK13548 93 VEE--VVA------MGRAP-HGLSRAEDdalVAAALAQVDlAHLAGRDYPQ---LSGGEQQrvqlarVLAQLWEPDGPPR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 172 LLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:PRK13548 161 WLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVAD 222
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
25-231 |
1.24e-29 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 110.54 E-value: 1.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKyLSRVFQDPKMGtaPRMTVAE 104
Cdd:cd03265 16 VRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRR-IGIVFQDLSVD--DELTGWE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLLV-AKFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALD 183
Cdd:cd03265 93 NLYIhARLYGVPG-------AERRERIDELLDFVG--LLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLD 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1080618511 184 PKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03265 164 PQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRII 211
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
5-238 |
1.27e-29 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 110.73 E-value: 1.27e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPV-----SSGKIYILGEDVtnYSPE 79
Cdd:cd03260 1 IELRDLNVYY-----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDI--YDLD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKYLSR----VFQDPkmgTAPRMTVAENL-LVAKFRGEKRGliprhlASYKEEFQTVLAKIGNGLENHIDTAVEFLSG 154
Cdd:cd03260 74 VDVLELRRrvgmVFQKP---NPFPGSIYDNVaYGLRLHGIKLK------EELDERVEEALRKAALWDEVKDRLHALGLSG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDALKYGNRLIVMKDGHIVQDL 234
Cdd:cd03260 145 GQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFG 222
|
....
gi 1080618511 235 NQEE 238
Cdd:cd03260 223 PTEQ 226
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
4-238 |
1.68e-29 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 110.95 E-value: 1.68e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA- 82
Cdd:PRK09493 1 MIEFKNVSKHFG-----PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLi 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 -KYLSRVFQdpKMGTAPRMTVAENLLVA--KFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQA 159
Cdd:PRK09493 76 rQEAGMVFQ--QFYLFPHLTALENVMFGplRVRGASK-------EEAEKQARELLAKVG--LAERAHHYPSELSGGQQQR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVkQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:PRK09493 145 VAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLA-EEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQV 222
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
5-230 |
1.71e-29 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 110.19 E-value: 1.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMneekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYsPEKRAKY 84
Cdd:cd03292 1 IEFINVTKTYPNGT----AALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDL-RGRAIPY 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPKMgtAPRMTVAENLLVA-KFRGEKRGLIPRHLASykeefqtVLAKIGngLENHIDTAVEFLSGGQRQA 159
Cdd:cd03292 76 LRRkigvVFQDFRL--LPDRNVYENVAFAlEVTGVPPREIRKRVPA-------ALELVG--LSHKHRALPAELSGGEQQR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:cd03292 145 VAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGT-TVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
5-233 |
1.99e-29 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 109.99 E-value: 1.99e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03245 3 IEFRNVSFSYPN---QEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKM--GT--------APRMTVAENLLVAKFRGEKRgLIPRHlasykeefqtvlakiGNGLENHIDTAVEFLSG 154
Cdd:cd03245 80 IGYVPQDVTLfyGTlrdnitlgAPLADDERILRAAELAGVTD-FVNKH---------------PNGLDLQIGERGRGLSG 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDalTALMITHHMEdALKYGNRLIVMKDGHIVQD 233
Cdd:cd03245 144 GQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDK--TLIIITHRPS-LLDLVDRIIVMDSGRIVAD 219
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
25-228 |
4.01e-29 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 109.48 E-value: 4.01e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAkylsrVFQDPKMgtAPRMTVAE 104
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMV-----VFQNYSL--LPWLTVRE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLLVA-------KFRGEKRGLIPRHLASYkeefqtvlakignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDE 177
Cdd:TIGR01184 74 NIALAvdrvlpdLSKSERRAIVEEHIALV-------------GLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDE 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 178 HTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:TIGR01184 141 PFGALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
7-233 |
4.12e-29 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 109.54 E-value: 4.12e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnyspekrakyls 86
Cdd:cd03220 20 LKKLGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSS------------ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 87 rvFQDPKMGTAPRMTVAENL-LVAKFRGEKRGLIPRHLASYkEEFqtvlakigNGLENHIDTAVEFLSGGQRQALSLLMA 165
Cdd:cd03220 88 --LLGLGGGFNPELTGRENIyLNGRLLGLSRKEIDEKIDEI-IEF--------SELGDFIDLPVKTYSSGMKARLAFAIA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 166 TLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03220 157 TALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGK-TVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
5-233 |
6.11e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 110.52 E-value: 6.11e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnyspEKRA-- 82
Cdd:PRK13637 3 IKIENLTHIYMEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDIT----DKKVkl 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 ----KYLSRVFQDPKMGTAPRmTVAENLLVAkfrgekrgliPRHLASYKEEFQTVLAK----IGNGLENHIDTAVEFLSG 154
Cdd:PRK13637 79 sdirKKVGLVFQYPEYQLFEE-TIEKDIAFG----------PINLGLSEEEIENRVKRamniVGLDYEDYKDKSPFELSG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:PRK13637 148 GQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQ 226
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-233 |
6.53e-29 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 109.40 E-value: 6.53e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTK--------------AVSNGMN---EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSS 63
Cdd:COG1134 1 MSSMIEVENVSKsyrlyhepsrslkeLLLRRRRtrrEEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 64 GKIYILGedvtnyspekrakylsRV---------FQdpkmgtaPRMTVAENL-LVAKFRGEKRGLIPRHLASYkEEFqtv 133
Cdd:COG1134 81 GRVEVNG----------------RVsallelgagFH-------PELTGRENIyLNGRLLGLSRKEIDEKFDEI-VEF--- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 134 lAkignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDP---KTSQALMtltDEFVKQDAlTALMITH 210
Cdd:COG1134 134 -A----ELGDFIDQPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAafqKKCLARI---RELRESGR-TVIFVSH 204
|
250 260
....*....|....*....|...
gi 1080618511 211 HMEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG1134 205 SMGAVRRLCDRAIWLEKGRLVMD 227
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
4-233 |
1.70e-28 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 108.16 E-value: 1.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNySPEKRAK 83
Cdd:COG1126 1 MIEIENLHKSFGD-----LEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTD-SKKDINK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR---VFQD----PkmgtapRMTVAENLLVA--KFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSG 154
Cdd:COG1126 75 LRRKvgmVFQQfnlfP------HLTVLENVTLApiKVKKMSK-------AEAEERAMELLERVG--LADKADAYPAQLSG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 155 GQRQ----ALSLLMatlkRPELLLLDEHTAALDPK-TSQALMTLTDefVKQDALTALMITHHMEDALKYGNRLIVMKDGH 229
Cdd:COG1126 140 GQQQrvaiARALAM----EPKVMLFDEPTSALDPElVGEVLDVMRD--LAKEGMTMVVVTHEMGFAREVADRVVFMDGGR 213
|
....
gi 1080618511 230 IVQD 233
Cdd:COG1126 214 IVEE 217
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
22-238 |
1.83e-28 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 108.01 E-value: 1.83e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK----YL---SRVFQdpkm 94
Cdd:cd03218 13 RKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARlgigYLpqeASIFR---- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 gtapRMTVAENLL-VAKFRGEKRGLIPRHLASYKEEFQtvLAKIGNGLENHidtavefLSGGQRQALSLLMATLKRPELL 173
Cdd:cd03218 89 ----KLTVEENILaVLEIRGLSKKEREEKLEELLEEFH--ITHLRKSKASS-------LSGGERRRVEIARALATNPKFL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 174 LLDEHTAALDPKTSQALMTLTdEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:cd03218 156 LLDEPFAGVDPIAVQDIQKII-KILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEE 219
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
5-232 |
5.01e-28 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 109.42 E-value: 5.01e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAky 84
Cdd:PRK11432 7 VVLKNITKRFGS-----NTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQRD-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtAPRMTVAENLLVakfrGEKRGLIPRhlASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALSLLM 164
Cdd:PRK11432 80 ICMVFQSYAL--FPHMSLGENVGY----GLKMLGVPK--EERKQRVKEALELV--DLAGFEDRYVDQISGGQQQRVALAR 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11432 150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQ 217
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
2-231 |
5.62e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 107.77 E-value: 5.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:PRK13632 5 SVMIKVENVSFSYPN---SENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYLSRVFQDPK---MGTAPRMTVA---ENllvakfRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGG 155
Cdd:PRK13632 82 RKKIGIIFQNPDnqfIGATVEDDIAfglEN------KKVPPKKMKDIIDDLAKKV---------GMEDYLDKEPQNLSGG 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 156 QRQ--ALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKyGNRLIVMKDGHIV 231
Cdd:PRK13632 147 QKQrvAIASVLAL--NPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLI 221
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
25-233 |
1.77e-27 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 105.07 E-value: 1.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIR---EHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILG------EDVTNYSPEKRAkyLSRVFQDPKMg 95
Cdd:cd03297 10 LPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGtvlfdsRKKINLPPQQRK--IGLVFQQYAL- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 96 tAPRMTVAENL---LVAKFRGEKRgliprhlasYKEEFQTVLAKIGNGLENHIDTavefLSGGQRQALSLLMATLKRPEL 172
Cdd:cd03297 87 -FPHLNVRENLafgLKRKRNREDR---------ISVDELLDLLGLDHLLNRYPAQ----LSGGEKQRVALARALAAQPEL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 173 LLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03297 153 LLLDEPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYI 213
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
25-231 |
2.46e-27 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 107.12 E-value: 2.46e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSR---VFQDPKMGTAPRMT 101
Cdd:COG4608 34 VDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELRPLRRRmqmVFQDPYASLNPRMT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 V----AENLLVAKF--RGEKR----------GLIPRHLASYKEEFqtvlakignglenhidtaveflSGGQRQ------A 159
Cdd:COG4608 114 VgdiiAEPLRIHGLasKAERRervaellelvGLRPEHADRYPHEF----------------------SGGQRQrigiarA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 160 LSLlmatlkRPELLLLDEHTAALDpKTSQA-----LMTLTDEFvkqdALTALMITH------HMEDalkygnRLIVMKDG 228
Cdd:COG4608 172 LAL------NPKLIVCDEPVSALD-VSIQAqvlnlLEDLQDEL----GLTYLFISHdlsvvrHISD------RVAVMYLG 234
|
...
gi 1080618511 229 HIV 231
Cdd:COG4608 235 KIV 237
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
4-231 |
3.61e-27 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 106.70 E-value: 3.61e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:COG1135 1 MIELENLSKTFPTK-GGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR---VFQDPKMgtAPRMTVAEN----LLVAKFRGEKRgliprhlasyKEEFQTVLAKIGngLENHIDTAVEFLSGGQ 156
Cdd:COG1135 80 ARRKigmIFQHFNL--LSSRTVAENvalpLEIAGVPKAEI----------RKRVAELLELVG--LSDKADAYPSQLSGGQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQ------ALsllmATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:COG1135 146 KQrvgiarAL----AN--NPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRI 219
|
.
gi 1080618511 231 V 231
Cdd:COG1135 220 V 220
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-238 |
3.70e-27 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 107.61 E-value: 3.70e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK11607 16 LTPLLEIRNLTKSF-----DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAkyLSRVFQDPKMgtAPRMTVAENLLVakfrGEKRGLIPR-HLASYKEEFQTVLakignglenHIDtavEF-------L 152
Cdd:PRK11607 91 RP--INMMFQSYAL--FPHMTVEQNIAF----GLKQDKLPKaEIASRVNEMLGLV---------HMQ---EFakrkphqL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 153 SGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11607 151 SGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQ 230
|
....*.
gi 1080618511 233 DLNQEE 238
Cdd:PRK11607 231 IGEPEE 236
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
22-231 |
3.92e-27 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 105.20 E-value: 3.92e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAprMT 101
Cdd:COG4559 14 RTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVLPQHSSLAFP--FT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 VAEnllVAKFrgekrGLIPrHLASYKEEFQTV---LAKIgnGLENHIDTAVEFLSGGQRQALSL--LMATLKRPE----- 171
Cdd:COG4559 92 VEE---VVAL-----GRAP-HGSSAAQDRQIVreaLALV--GLAHLAGRSYQTLSGGEQQRVQLarVLAQLWEPVdggpr 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 172 LLLLDEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG4559 161 WLFLDEPTSALDLAHQHAVLRLARQLARRG-GGVVAVLHDLNLAAQYADRILLLHQGRLV 219
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-230 |
7.18e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 104.81 E-value: 7.18e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNgmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP-E 79
Cdd:PRK13650 1 MSNIIEVKNLTFKYKE--DQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVwD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKyLSRVFQDPK---MGTaprmTVAENllVAkFRGEKRGLiprHLASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQ 156
Cdd:PRK13650 79 IRHK-IGMVFQNPDnqfVGA----TVEDD--VA-FGLENKGI---PHEEMKERVNEALELV--GMQDFKEREPARLSGGQ 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMeDALKYGNRLIVMKDGHI 230
Cdd:PRK13650 146 KQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDL-DEVALSDRVLVMKNGQV 218
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
5-232 |
2.00e-26 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 102.19 E-value: 2.00e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTkavsngMN---EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:cd03244 3 IEFKNVS------LRyrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYLSRVFQDPKMGTAprmTVAENllvakfrgekrgLIPRHLASyKEEFQTVLAKIG-----NGLENHIDTAVE----FL 152
Cdd:cd03244 77 RSRISIIPQDPVLFSG---TIRSN------------LDPFGEYS-DEELWQALERVGlkefvESLPGGLDTVVEeggeNL 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 153 SGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDALKYgNRLIVMKDGHIVQ 232
Cdd:cd03244 141 SVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIREAFKD--CTVLTIAHRLDTIIDS-DRILVLDKGRVVE 217
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
10-211 |
2.14e-26 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 107.06 E-value: 2.14e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 10 VTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVF 89
Cdd:TIGR02868 336 ELRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 90 QDPKMGTAprmTVAENLLVAkfRGEKRGliprhlasykEEFQTVLAKIgnGLENHI-------DTAV----EFLSGGQRQ 158
Cdd:TIGR02868 416 QDAHLFDT---TVRENLRLA--RPDATD----------EELWAALERV--GLADWLralpdglDTVLgeggARLSGGERQ 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALmtLTDEFVKQDALTALMITHH 211
Cdd:TIGR02868 479 RLALARALLADAPILLLDEPTEHLDAETADEL--LEDLLAALSGRTVVLITHH 529
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
22-232 |
3.58e-26 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 106.47 E-value: 3.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSsGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMgtaPRMT 101
Cdd:PRK11174 363 KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLKINGIELRELDPESWRKHLSWVGQNPQL---PHGT 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 VAENLLVAKfrgekrgliprHLASyKEEFQTVLAKIG-----NGLENHIDTAVE----FLSGGQRQALSLLMATLKRPEL 172
Cdd:PRK11174 439 LRDNVLLGN-----------PDAS-DEQLQQALENAWvseflPLLPQGLDTPIGdqaaGLSVGQAQRLALARALLQPCQL 506
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 173 LLLDEHTAALDPKTSQALM-TLTDEFVKQdalTALMITHHMEDaLKYGNRLIVMKDGHIVQ 232
Cdd:PRK11174 507 LLLDEPTASLDAHSEQLVMqALNAASRRQ---TTLMVTHQLED-LAQWDQIWVMQDGQIVQ 563
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
26-228 |
6.82e-26 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 101.61 E-value: 6.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 26 DDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA-KYLSRVFQDPKMgtAPRMTVAE 104
Cdd:PRK11300 22 NNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIArMGVVRTFQHVRL--FREMTVIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLLVAKFRGEKRGLIPRHLA--SYKEEFQTVLAKIGN-----GLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDE 177
Cdd:PRK11300 100 NLLVAQHQQLKTGLFSGLLKtpAFRRAESEALDRAATwlervGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDE 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 178 HTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:PRK11300 180 PAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQG 230
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
6-230 |
7.19e-26 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 99.60 E-value: 7.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYL 85
Cdd:cd03246 2 EVENVSFRYPGA---EPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVFQDPKMGTAprmTVAENLlvakfrgekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALSLLMA 165
Cdd:cd03246 79 GYLPQDDELFSG---SIAENI---------------------------------------------LSGGQRQRLGLARA 110
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 166 TLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEdALKYGNRLIVMKDGHI 230
Cdd:cd03246 111 LYGNPRILVLDEPNSHLDVEGERALNQAIAA-LKAAGATRIVIAHRPE-TLASADRILVLEDGRV 173
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
14-231 |
7.60e-26 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 100.41 E-value: 7.60e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 14 VSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtnySPEKRAKYLSRVFQDP- 92
Cdd:cd03226 5 ISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI---KAKERRKSIGYVMQDVd 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 93 -KMGTAprmTVAENLLVAKfrgekrglipRHLASYKEEFQTVLAKIG-NGL-ENHIDTavefLSGGQRQALSLLMATLKR 169
Cdd:cd03226 82 yQLFTD---SVREELLLGL----------KELDAGNEQAETVLKDLDlYALkERHPLS----LSGGQKQRLAIAAALLSG 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 170 PELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03226 145 KDLLIFDEPTSGLDYKNMERVGELIRELAAQGK-AVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
5-232 |
1.60e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 101.44 E-value: 1.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:PRK13641 3 IKFENVDYIYSPGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPKMGTAPRmTVAENLLVAkfrgekrgliPRHLASYKEEFQTV----LAKIGNGlENHIDTAVEFLSGGQ 156
Cdd:PRK13641 83 LRKkvslVFQFPEAQLFEN-TVLKDVEFG----------PKNFGFSEDEAKEKalkwLKKVGLS-EDLISKSPFELSGGQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 157 --RQALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK13641 151 mrRVAIAGVMAY--EPEILCLDEPAAGLDPEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLIK 225
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-231 |
3.30e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 100.95 E-value: 3.30e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTN-------Y 76
Cdd:COG4152 1 MLELKGLTKRFGD-----KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPedrrrigY 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 77 SPEKRAKYlsrvfqdpkmgtaPRMTVAENLL-VAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGG 155
Cdd:COG4152 76 LPEERGLY-------------PKMKVGEQLVyLARLKGLSKAEAKRRADEWLERL---------GLGDRANKKVEELSKG 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG4152 134 NQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGT-TVIFSSHQMELVEELCDRIVIINKGRKV 208
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
27-231 |
5.11e-25 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 101.33 E-value: 5.11e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 27 DVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDV------TNYSPEKRAkyLSRVFQDPKMgtAPRM 100
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqdsargIFLPPHRRR--IGYVFQEARL--FPHL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAENLLVakfrGEKRglIPRHLAsyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTA 180
Cdd:COG4148 93 SVRGNLLY----GRKR--APRAER--RISFDEVVELL--GIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLA 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 181 ALDPKTSQALM----TLTDEFvkqdALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG4148 163 ALDLARKAEILpyleRLRDEL----DIPILYVSHSLDEVARLADHVVLLEQGRVV 213
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
19-233 |
6.26e-25 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 97.38 E-value: 6.26e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 19 NEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpEKRAKYLSRVFQDPKMGTAp 98
Cdd:cd03247 12 EQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLE-KALSSLISVLNQRPYLFDT- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 rmTVAENLlvakfrGEKrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQALSLLMATLKRPELLLLDEH 178
Cdd:cd03247 90 --TLRNNL------GRR------------------------------------FSGGERQRLALARILLQDAPIVLLDEP 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 179 TAALDPKTSQALMTLTDEFVKQDalTALMITHHMEdALKYGNRLIVMKDGHIVQD 233
Cdd:cd03247 126 TVGLDPITERQLLSLIFEVLKDK--TLIWITHHLT-GIEHMDKILFLENGKIIMQ 177
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
16-232 |
8.55e-25 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 99.11 E-value: 8.55e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 16 NGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY---LSRVFQDP 92
Cdd:TIGR02769 18 FGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQRRAFrrdVQLVFQDS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 93 KMGTAPRMTVAENLlvakfrGEKRglipRHLASYKEEFQtvLAKIGNGLE------NHIDTAVEFLSGGQRQALSLLMAT 166
Cdd:TIGR02769 98 PSAVNPRMTVRQII------GEPL----RHLTSLDESEQ--KARIAELLDmvglrsEDADKLPRQLSGGQLQRINIARAL 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 167 LKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:TIGR02769 166 AVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVE 231
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-231 |
9.52e-25 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 102.07 E-value: 9.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyILGEDVT-NYSPEKRA 82
Cdd:COG0488 315 VLELEGLSKSY-----GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV-KLGETVKiGYFDQHQE 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 kYLSrvfqdpkmgtaPRMTVAENLlvakfRGEKRGLIPRHLASYKEEFqtvlakigngL--ENHIDTAVEFLSGGQRQAL 160
Cdd:COG0488 389 -ELD-----------PDKTVLDEL-----RDGAPGGTEQEVRGYLGRF----------LfsGDDAFKPVGVLSGGEKARL 441
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALmtltdefvkQDAL-----TALMITHHME--DALkyGNRLIVMKDGHIV 231
Cdd:COG0488 442 ALAKLLLSPPNVLLLDEPTNHLDIETLEAL---------EEALddfpgTVLLVSHDRYflDRV--ATRILEFEDGGVR 508
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
19-231 |
1.06e-24 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 98.93 E-value: 1.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 19 NEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP-EKRAKyLSRVFQDPK---M 94
Cdd:PRK13635 17 DAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVwDVRRQ-VGMVFQNPDnqfV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 GTaprmTVAENllVAkFRGEKRGlIPRHLASykEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLL 174
Cdd:PRK13635 96 GA----TVQDD--VA-FGLENIG-VPREEMV--ERVDQALRQVG--MEDFLNREPHRLSGGQKQRVAIAGVLALQPDIII 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 175 LDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKyGNRLIVMKDGHIV 231
Cdd:PRK13635 164 LDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEIL 219
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
5-229 |
1.18e-24 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 100.29 E-value: 1.18e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtnysPEKRAKY 84
Cdd:PRK13536 42 IDLAGVSKSYGD-----KAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPV----PARARLA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTA-PRMTVAENLLV--AKFRGEKR---GLIPRHLasykeEFQTvlakigngLENHIDTAVEFLSGGQRQ 158
Cdd:PRK13536 113 RARIGVVPQFDNLdLEFTVRENLLVfgRYFGMSTReieAVIPSLL-----EFAR--------LESKADARVSDLSGGMKR 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGH 229
Cdd:PRK13536 180 RLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGR 249
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
6-232 |
2.20e-24 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 97.45 E-value: 2.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAG--TLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:COG0396 2 EIKNLHVSV-----EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGhpKYEVTSGSILLDGEDILELSPDERAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 ---YLSrvFQDPkmgtaPR---MTVAENLLVAKfrgEKRGLIPRHLASYKEEFQTVLAKIGngL-ENHIDTAV-EFLSGG 155
Cdd:COG0396 77 agiFLA--FQYP-----VEipgVSVSNFLRTAL---NARRGEELSAREFLKLLKEKMKELG--LdEDFLDRYVnEGFSGG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 156 QRQALSLL-MATLKrPELLLLDEHTAALDpktSQALMTLTDEF--VKQDALTALMITHHmEDALKYGN--RLIVMKDGHI 230
Cdd:COG0396 145 EKKRNEILqMLLLE-PKLAILDETDSGLD---IDALRIVAEGVnkLRSPDRGILIITHY-QRILDYIKpdFVHVLVDGRI 219
|
..
gi 1080618511 231 VQ 232
Cdd:COG0396 220 VK 221
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-246 |
2.65e-24 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 101.34 E-value: 2.65e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNtIAGTL-PVSSGKIYILGEDVTNYSPE 79
Cdd:PRK10535 1 MTALLELKDIRRSYPSG-EEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMN-ILGCLdKPTSGTYRVAGQDVATLDAD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 K----RAKYLSRVFQdpKMGTAPRMTVAENLLV-AKFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSG 154
Cdd:PRK10535 79 AlaqlRREHFGFIFQ--RYHLLSHLTAAQNVEVpAVYAGLER-------KQRLLRAQELLQRLG--LEDRVEYQPSQLSG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKyGNRLIVMKDGHIVQDL 234
Cdd:PRK10535 148 GQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQ-LRDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIVRNP 225
|
250
....*....|..
gi 1080618511 235 NQEEKAQMTIAD 246
Cdd:PRK10535 226 PAQEKVNVAGGT 237
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
25-231 |
2.78e-24 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 97.26 E-value: 2.78e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYS------------PEKRakylsRVFQdp 92
Cdd:PRK11614 21 LHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQtakimreavaivPEGR-----RVFS-- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 93 kmgtapRMTVAENLLVAKFRGEKRgliprhlaSYKEEFQTVLAKIGNGLENHIDTAVEfLSGGQRQALSLLMATLKRPEL 172
Cdd:PRK11614 94 ------RMTVEENLAMGGFFAERD--------QFQERIKWVYELFPRLHERRIQRAGT-MSGGEQQMLAIGRALMSQPRL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 173 LLLDEHTAALDPKTSQALMTlTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK11614 159 LLLDEPSLGLAPIIIQQIFD-TIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVV 216
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
7-233 |
6.68e-24 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 95.86 E-value: 6.68e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDvtnysP-EKRAKYL 85
Cdd:cd03267 19 LIGSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLV-----PwKRRKKFL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SR---VFqdpkmgtAPRMTVAENLLVAK-FRGEKR--GLIPRHLASYKEEFQTVLAkigngLENHIDTAVEFLSGGQRQA 159
Cdd:cd03267 94 RRigvVF-------GQKTQLWWDLPVIDsFYLLAAiyDLPPARFKKRLDELSELLD-----LEELLDTPVRQLSLGQRMR 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:cd03267 162 AEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYD 235
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
5-238 |
7.96e-24 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 95.76 E-value: 7.96e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03251 1 VEFKNVTFRYPG---DGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTAprmTVAENLLVAKFRGEKRGLIPRHLASYKEEFqtvLAKIGNGLENHI-DTAVEfLSGGQRQALSLL 163
Cdd:cd03251 78 IGLVSQDVFLFND---TVAENIAYGRPGATREEVEEAARAANAHEF---IMELPEGYDTVIgERGVK-LSGGQRQRIAIA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTsqalmtltdEFVKQDAL-------TALMITHHM---EDAlkygNRLIVMKDGHIVQD 233
Cdd:cd03251 151 RALLKDPPILILDEATSALDTES---------ERLVQAALerlmknrTTFVIAHRLstiENA----DRIVVLEDGKIVER 217
|
....*
gi 1080618511 234 LNQEE 238
Cdd:cd03251 218 GTHEE 222
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
21-231 |
1.55e-23 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 95.47 E-value: 1.55e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVfqdPKMGTAPR- 99
Cdd:PRK11231 14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALL---PQHHLTPEg 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 MTVAEnlLVAKFRGEKRGLIPRHLASYKEEFQTVLAKigNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHT 179
Cdd:PRK11231 91 ITVRE--LVAYGRSPWLSLWGRLSAEDNARVNQAMEQ--TRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPT 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 180 AALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK11231 167 TYLDINHQVELMRLMRE-LNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVM 217
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
25-216 |
2.23e-23 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 93.45 E-value: 2.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlgedvtnySPEKRAKYLsrvfqdPKMGTAPR---MT 101
Cdd:NF040873 8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRR--------AGGARVAYV------PQRSEVPDslpLT 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 VAEnlLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIG-NGLENHidtAVEFLSGGQRQALSLLMATLKRPELLLLDEHTA 180
Cdd:NF040873 74 VRD--LVAMGRWARRGLWRRLTRDDRAAVDDALERVGlADLAGR---QLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
|
170 180 190
....*....|....*....|....*....|....*.
gi 1080618511 181 ALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDAL 216
Cdd:NF040873 149 GLDAESRERIIALLAEEHARGA-TVVVVTHDLELVR 183
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
5-225 |
3.70e-23 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 97.74 E-value: 3.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNeekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:TIGR02857 322 LEFSGVSVAYPGRRP----ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQ 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTAprmTVAENLLVAKfRGEKRGLIPRhlASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLM 164
Cdd:TIGR02857 398 IAWVPQHPFLFAG---TIAENIRLAR-PDASDAEIRE--ALERAGLDEFVAALPQGLDTPIGEGGAGLSGGQAQRLALAR 471
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKqdALTALMITHHMEDALKYgNRLIVM 225
Cdd:TIGR02857 472 AFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALA-DRIVVL 529
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
2-210 |
3.94e-23 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 93.63 E-value: 3.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:PRK10247 5 SPLLQLQNVGYLA-----GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYLSRVFQDPKM-GTaprmTVAENLLvakFRGEKRGLIPRhlasyKEEFQTVLAKIgnGLENHI-DTAVEFLSGGQRQA 159
Cdd:PRK10247 80 RQQVSYCAQTPTLfGD----TVYDNLI---FPWQIRNQQPD-----PAIFLDDLERF--ALPDTIlTKNIAELSGGEKQR 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITH 210
Cdd:PRK10247 146 ISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTH 196
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-228 |
3.94e-23 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 95.26 E-value: 3.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK13537 4 SVAPIDFRNVEKRYG-----DKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAkylsRVFQDPKMGTA-PRMTVAENLLV-AKFRG----EKRGLIPRHLasykeEFqtvlAKigngLENHIDTAVEFLSG 154
Cdd:PRK13537 79 RQ----RVGVVPQFDNLdPDFTVRENLLVfGRYFGlsaaAARALVPPLL-----EF----AK----LENKADAKVGELSG 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKtSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:PRK13537 142 GMKRRLTLARALVNDPDVLVLDEPTTGLDPQ-ARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEG 214
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
25-231 |
5.26e-23 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 97.06 E-value: 5.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPvSSGKIYILGEDVTNYSPEKRAKYLSR---VFQDPkMGT-APRM 100
Cdd:COG4172 302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSRRALRPLRRRmqvVFQDP-FGSlSPRM 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TV----AENLLV---AKFRGEKR----------GLIPRHLASYKEEFqtvlakignglenhidtaveflSGGQRQ----- 158
Cdd:COG4172 380 TVgqiiAEGLRVhgpGLSAAERRarvaealeevGLDPAARHRYPHEF----------------------SGGQRQriaia 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 159 -ALSLlmatlkRPELLLLDEHTAALDpKTSQA-----LMTLTDEFvkqdALTALMITHHME--DALkyGNRLIVMKDGHI 230
Cdd:COG4172 438 rALIL------EPKLLVLDEPTSALD-VSVQAqildlLRDLQREH----GLAYLFISHDLAvvRAL--AHRVMVMKDGKV 504
|
.
gi 1080618511 231 V 231
Cdd:COG4172 505 V 505
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
4-231 |
7.60e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 94.28 E-value: 7.60e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYS--PEKR 81
Cdd:PRK13644 1 MIRLENVSYSYPDGTPA----LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSklQGIR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 aKYLSRVFQDPKMGTAPRmTVAENLlvaKFRGEKRGLIPRHLasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALS 161
Cdd:PRK13644 77 -KLVGIVFQNPETQFVGR-TVEEDL---AFGPENLCLPPIEI---RKRVDRALAEI--GLEKYRHRSPKTLSGGQGQCVA 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDaLKYGNRLIVMKDGHIV 231
Cdd:PRK13644 147 LAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKK-LHEKGKTIVYITHNLEE-LHDADRIIVMDRGKIV 214
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
22-184 |
7.65e-23 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 93.17 E-value: 7.65e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK----YL---SRVFQdpkm 94
Cdd:COG1137 16 RTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRARlgigYLpqeASIFR---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 gtapRMTVAENLL-VAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELL 173
Cdd:COG1137 92 ----KLTVEDNILaVLELRKLSKKEREERLEELLEEF---------GITHLRKSKAYSLSGGERRRVEIARALATNPKFI 158
|
170
....*....|.
gi 1080618511 174 LLDEHTAALDP 184
Cdd:COG1137 159 LLDEPFAGVDP 169
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
5-231 |
9.24e-23 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 94.87 E-value: 9.24e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpekrAKY 84
Cdd:PRK11153 2 IELKNISKVFPQGGRT-IHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALS----EKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQdpKMGtaprM-----------TVAENllVA---KFRGEKRGLIPRHLAsykEEFQTVlakignGLENHIDTAVE 150
Cdd:PRK11153 77 LRKARR--QIG----MifqhfnllssrTVFDN--VAlplELAGTPKAEIKARVT---ELLELV------GLSDKADRYPA 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 151 FLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:PRK11153 140 QLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRL 219
|
.
gi 1080618511 231 V 231
Cdd:PRK11153 220 V 220
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
21-231 |
9.71e-23 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 93.51 E-value: 9.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDpkmGTAP-R 99
Cdd:PRK10253 19 KYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQN---ATTPgD 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 MTVAEnlLVAKFRGEKRGLIPRhlasYKEEFQTVLAKI--GNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDE 177
Cdd:PRK10253 96 ITVQE--LVARGRYPHQPLFTR----WRKEDEEAVTKAmqATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDE 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 178 HTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK10253 170 PTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIV 223
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
21-232 |
1.14e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 93.93 E-value: 1.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlGEDVTnySPEKRAKYLSR-------VFQDPK 93
Cdd:PRK13634 19 ERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVI--TAGKKNKKLKPlrkkvgiVFQFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 MGTAPRmTVAE-------NLLVAKFRGEKRGliprhlasyKEEFQTVlakignGLENHIDTAVEF-LSGGQ--RQALSLL 163
Cdd:PRK13634 96 HQLFEE-TVEKdicfgpmNFGVSEEDAKQKA---------REMIELV------GLPEELLARSPFeLSGGQmrRVAIAGV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 164 MATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK13634 160 LAM--EPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFL 226
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
5-254 |
1.63e-22 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 92.29 E-value: 1.63e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTkavsNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03253 1 IEFENVT----FAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTAprmTVAENLLVAK--------FRGEKRGLIPRHLASYKEEFQTVLAKigNGLEnhidtavefLSGGQ 156
Cdd:cd03253 77 IGVVPQDTVLFND---TIGYNIRYGRpdatdeevIEAAKAAQIHDKIMRFPDGYDTIVGE--RGLK---------LSGGE 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALM-TLTDEFVKQdalTALMITHHME---DALKygnrLIVMKDGHIVQ 232
Cdd:cd03253 143 KQRVAIARAILKNPPILLLDEATSALDTHTEREIQaALRDVSKGR---TTIVIAHRLStivNADK----IIVLKDGRIVE 215
|
250 260
....*....|....*....|....*
gi 1080618511 233 DLNQEEkaqmTIAD---YYELFEKE 254
Cdd:cd03253 216 RGTHEE----LLAKgglYAEMWKAQ 236
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
20-238 |
2.09e-22 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 92.16 E-value: 2.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKM----- 94
Cdd:cd03252 13 DGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQENVLfnrsi 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 -----GTAPRMTVAENLLVAKFRGEKrglipRHLASYKEEFQTVLAKIGNGlenhidtavefLSGGQRQALSLLMATLKR 169
Cdd:cd03252 93 rdniaLADPGMSMERVIEAAKLAGAH-----DFISELPEGYDTIVGEQGAG-----------LSGGQRQRIAIARALIHN 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 170 PELLLLDEHTAALDPKTSQALMTLTDEFVkqDALTALMITHHMEdALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:cd03252 157 PRILIFDEATSALDYESEHAIMRNMHDIC--AGRTVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDE 222
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
4-231 |
2.16e-22 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 91.66 E-value: 2.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtnySPEKRAK 83
Cdd:cd03266 1 MITADALTKRFRD-VKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDV---VKEPAEA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSRVFQDPKMGTAPRMTVAENLLvakFRGEKRGLIPRHLASYKEEFQTVLakignGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:cd03266 77 RRRLGFVSDSTGLYDRLTARENLE---YFAGLYGLKGDELTARLEELADRL-----GMEELLDRRVGGFSTGMRQKVAIA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMtltdEFVKQ--DALTALMI-THHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03266 149 RALVHDPPVLLLDEPTTGLDVMATRALR----EFIRQlrALGKCILFsTHIMQEVERLCDRVVVLHRGRVV 215
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
24-232 |
2.66e-22 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 92.00 E-value: 2.66e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGE--DVTNYSPEKRAKYLSR----VFQDPKMGta 97
Cdd:PRK11124 17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfDFSKTPSDKAIRELRRnvgmVFQQYNLW-- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 98 PRMTVAENLLVAKFRgeKRGLIPrhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDE 177
Cdd:PRK11124 95 PHLTVQQNLIEAPCR--VLGLSK---DQALARAEKLLERLR--LKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDE 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 178 HTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11124 168 PTAALDPEITAQIVSIIRE-LAETGITQVIVTHEVEVARKTASRVVYMENGHIVE 221
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
4-231 |
7.83e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 91.45 E-value: 7.83e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtNYSPE---K 80
Cdd:PRK13636 5 ILKVEELNYNYSDGTHA----LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI-DYSRKglmK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDPkmgtaprmtvaENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAKI--GNGLENHIDTAVEFLSGGQRQ 158
Cdd:PRK13636 80 LRESVGMVFQDP-----------DNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNAlkRTGIEHLKDKPTHCLSFGQKK 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK13636 149 RVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
3-232 |
1.39e-21 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 91.83 E-value: 1.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 3 AIVELKNVTKAVSNGMNeekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA 82
Cdd:PRK11650 2 AGLKLQAVRKSYDGKTQ----VIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPADRD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 kyLSRVFQDpkmgTA--PRMTVAENLLVA-KFRGEKRGLIPRHLASykeefqtvLAKIgNGLENHIDTAVEFLSGGQRQA 159
Cdd:PRK11650 78 --IAMVFQN----YAlyPHMSVRENMAYGlKIRGMPKAEIEERVAE--------AARI-LELEPLLDRKPRELSGGQRQR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTsQALMTLtdEFVK-QDAL--TALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11650 143 VAMGRAIVREPAVFLFDEPLSNLDAKL-RVQMRL--EIQRlHRRLktTSLYVTHDQVEAMTLADRVVVMNGGVAEQ 215
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
2-232 |
1.67e-21 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 92.89 E-value: 1.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:COG4618 328 KGRLSVENLTVVPPGS---KRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREEL 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AK---YLSrvfQDPKM--GTaprmtVAENllVAKFRG---EKrgliprhlasykeefqtVL--AK-------IG---NGL 141
Cdd:COG4618 405 GRhigYLP---QDVELfdGT-----IAEN--IARFGDadpEK-----------------VVaaAKlagvhemILrlpDGY 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 142 ENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEdALKYGNR 221
Cdd:COG4618 458 DTRIGEGGARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRA-LKARGATVVVITHRPS-LLAAVDK 535
|
250
....*....|.
gi 1080618511 222 LIVMKDGHIVQ 232
Cdd:COG4618 536 LLVLRDGRVQA 546
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
5-232 |
1.84e-21 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 89.69 E-value: 1.84e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKavSNGMNEekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGE--DVTNYSPEKRA 82
Cdd:COG4161 3 IQLKNINC--FYGSHQ---ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfDFSQKPSEKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 KYLSR----VFQDPKMGtaPRMTVAENLLVAKFRGEKrglIPRHLAsyKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQ 158
Cdd:COG4161 78 RLLRQkvgmVFQQYNLW--PHLTVMENLIEAPCKVLG---LSKEQA--REKAMKLLARLR--LTDKADRFPLHLSGGQQQ 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPK-TSQALMTLTDefVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:COG4161 149 RVAIARALMMEPQVLLFDEPTAALDPEiTAQVVEIIRE--LSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIE 221
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
5-232 |
1.86e-21 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 91.68 E-value: 1.86e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpeKRAKY 84
Cdd:PRK10851 3 IEIANIKKSFGR-----TQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLH--ARDRK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTapRMTVAENLlvaKFrgekrGL--IPRH----LASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQ 158
Cdd:PRK10851 76 VGFVFQHYALFR--HMTVFDNI---AF-----GLtvLPRRerpnAAAIKAKVTQLLEMVQ--LAHLADRYPAQLSGGQKQ 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK10851 144 RVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQ 217
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
2-238 |
2.85e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 89.81 E-value: 2.85e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:PRK13648 5 NSIIVFKNVSFQYQS---DASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYLSRVFQDPK---MGTAPRMTVAENLlvakfrgekrgliPRHLASYKEEFQTVLAKIGN-GLENHIDTAVEFLSGGQR 157
Cdd:PRK13648 82 RKHIGIVFQNPDnqfVGSIVKYDVAFGL-------------ENHAVPYDEMHRRVSEALKQvDMLERADYEPNALSGGQK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKyGNRLIVMKDGHIVQDLNQE 237
Cdd:PRK13648 149 QRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPT 227
|
.
gi 1080618511 238 E 238
Cdd:PRK13648 228 E 228
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
18-253 |
4.19e-21 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 91.81 E-value: 4.19e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 18 MNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTA 97
Cdd:PRK11160 349 PDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISVVSQRVHLFSA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 98 prmTVAENLLVAKfrgekrgliprHLASyKEEFQTVLAKIgnGLENHIDTAVEF----------LSGGQRQALSLLMATL 167
Cdd:PRK11160 429 ---TLRDNLLLAA-----------PNAS-DEALIEVLQQV--GLEKLLEDDKGLnawlgeggrqLSGGEQRRLGIARALL 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 168 KRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDalTALMITHHMEdALKYGNRLIVMKDGHIV-----QDLNQEEKAqm 242
Cdd:PRK11160 492 HDAPLLLLDEPTEGLDAETERQILELLAEHAQNK--TVLMITHRLT-GLEQFDRICVMDNGQIIeqgthQELLAQQGR-- 566
|
250
....*....|.
gi 1080618511 243 tiadYYELFEK 253
Cdd:PRK11160 567 ----YYQLKQR 573
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
5-230 |
5.61e-21 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 91.64 E-value: 5.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:TIGR01842 317 LSVENVTIVPPGG---KKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKH 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTAprmTVAENllVAKFRgekRGLIPRH------LASYKEefqtVLAKIGNGLENHIDTAVEFLSGGQRQ 158
Cdd:TIGR01842 394 IGYLPQDVELFPG---TVAEN--IARFG---ENADPEKiieaakLAGVHE----LILRLPDGYDTVIGPGGATLSGGQRQ 461
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALM-TLTDefVKQDALTALMITHHMEdALKYGNRLIVMKDGHI 230
Cdd:TIGR01842 462 RIALARALYGDPKLVVLDEPNSNLDEEGEQALAnAIKA--LKARGITVVVITHRPS-LLGCVDKILVLQDGRI 531
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
22-234 |
7.65e-21 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 88.22 E-value: 7.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAkylsrVFQDPkmGTAPRMT 101
Cdd:PRK11248 14 KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAERGV-----VFQNE--GLLPWRN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 VAENllVAkFRGEKRGlIPRhlASYKEEFQTVLAKIG-NGLENHIdtaVEFLSGGQRQALSLLMATLKRPELLLLDEHTA 180
Cdd:PRK11248 87 VQDN--VA-FGLQLAG-VEK--MQRLEIAHQMLKKVGlEGAEKRY---IWQLSGGQRQRVGIARALAANPQLLLLDEPFG 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 181 ALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMK--DGHIVQDL 234
Cdd:PRK11248 158 ALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSpgPGRVVERL 213
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
12-251 |
8.90e-21 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 90.09 E-value: 8.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 12 KAVSNGMNEEKVI--------LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP----E 79
Cdd:PRK10070 23 KYIEQGLSKEQILektglslgVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDaelrE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKYLSRVFQdpKMGTAPRMTVAENllvAKFRGEKRGLIPrhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQA 159
Cdd:PRK10070 103 VRRKKIAMVFQ--SFALMPHMTVLDN---TAFGMELAGINA---EERREKALDALRQVG--LENYAHSYPDELSGGMRQR 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMtltDEFVKQDA---LTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQ 236
Cdd:PRK10070 173 VGLARALAINPDILLMDEAFSALDPLIRTEMQ---DELVKLQAkhqRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP 249
|
250
....*....|....*
gi 1080618511 237 EEKAQMTIADYYELF 251
Cdd:PRK10070 250 DEILNNPANDYVRTF 264
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
4-254 |
9.50e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 88.21 E-value: 9.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVT--NYSPEKR 81
Cdd:PRK13639 1 ILETRDLKYSYPDG----TEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKydKKSLLEV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYLSRVFQDPkmgtaprmtvaENLLVAKFRGEKRGLIPRHLASYKEEFQT----VLAKIgnGLENHIDTAVEFLSGGQR 157
Cdd:PRK13639 77 RKTVGIVFQNP-----------DDQLFAPTVEEDVAFGPLNLGLSKEEVEKrvkeALKAV--GMEGFENKPPHHLSGGQK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGHIVQ----- 232
Cdd:PRK13639 144 KRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKegtpk 222
|
250 260
....*....|....*....|....*....
gi 1080618511 233 ----DLNQEEKAQMT---IADYYELFEKE 254
Cdd:PRK13639 223 evfsDIETIRKANLRlprVAHLIEILNKE 251
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
26-232 |
1.51e-20 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 88.61 E-value: 1.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 26 DDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA---KYLSRVFQDPKMGTAPRMTV 102
Cdd:PRK15079 38 DGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRavrSDIQMIFQDPLASLNPRMTI 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 103 AEnllvakfrgekrgLIPRHLASY---------KEEFQTVLAKIGNgLENHIDTAVEFLSGGQRQALSLLMATLKRPELL 173
Cdd:PRK15079 118 GE-------------IIAEPLRTYhpklsrqevKDRVKAMMLKVGL-LPNLINRYPHEFSGGQCQRIGIARALILEPKLI 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 174 LLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITH------HMEDalkygnRLIVMKDGHIVQ 232
Cdd:PRK15079 184 ICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHdlavvkHISD------RVLVMYLGHAVE 242
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
5-232 |
1.72e-20 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 90.16 E-value: 1.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTkaVSNGMNEEKViLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:TIGR02203 331 VEFRNVT--FRYPGRDRPA-LDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQ 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTAprmTVAENLLVAKFRGEKRGLIPRHL-ASYKEEFQtvlakigNGLENHIDTAV----EFLSGGQRQA 159
Cdd:TIGR02203 408 VALVSQDVVLFND---TIANNIAYGRTEQADRAEIERALaAAYAQDFV-------DKLPLGLDTPIgengVLLSGGQRQR 477
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALmtltdefvkQDALTALM------ITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:TIGR02203 478 LAIARALLKDAPILILDEATSALDNESERLV---------QAALERLMqgrttlVIAHRLSTIEKADRIVVMDDGRIVE 547
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
7-234 |
1.85e-20 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 87.43 E-value: 1.85e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGtLPVSSGkiyilGEDVTNYSPEKRAKYLS 86
Cdd:PRK11247 15 LNAVSKRYG-----ERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAG-LETPSA-----GELLAGTAPLAEAREDT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 87 RV-FQDPKMgtAPRMTVAENLlvakfrgekrGLIPRhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMA 165
Cdd:PRK11247 84 RLmFQDARL--LPWKKVIDNV----------GLGLK--GQWRDAALQALAAVG--LADRANEWPAALSGGQKQRVALARA 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 166 TLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDL 234
Cdd:PRK11247 148 LIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDL 216
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
5-232 |
2.18e-20 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 85.93 E-value: 2.18e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTkaVSNGMNEEKViLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03369 7 IEVENLS--VRYAPDLPPV-LKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtaprmtvaenllvakFRGEKRGLIPRHLASYKEEFQTVLaKIGNGLENhidtavefLSGGQRQALSLLM 164
Cdd:cd03369 84 LTIIPQDPTL----------------FSGTIRSNLDPFDEYSDEEIYGAL-RVSEGGLN--------LSQGQRQLLCLAR 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALM-TLTDEFVKQdalTALMITHHMEDALKYgNRLIVMKDGHIVQ 232
Cdd:cd03369 139 ALLKRPRVLVLDEATASIDYATDALIQkTIREEFTNS---TILTIAHRLRTIIDY-DKILVMDAGEVKE 203
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
1-231 |
2.25e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 87.48 E-value: 2.25e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK13647 1 MDNIIEVEDLHFRYKDGTKA----LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKW 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDPKmGTAPRMTVAENllVAkFRGEKRGLIPRHLasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQAL 160
Cdd:PRK13647 77 VRSKVGLVFQDPD-DQVFSSTVWDD--VA-FGPVNMGLDKDEV---ERRVEEALKAV--RMWDFRDKPPYHLSYGQKKRV 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK13647 148 AIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGK-TVIVATHDVDLAAEWADQVIVLKEGRVL 217
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
5-230 |
2.43e-20 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 89.13 E-value: 2.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVtkAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpekrAKY 84
Cdd:PRK09536 4 IDVSDL--SVEFG---DTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALS----ARA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRvfqdpKMGTAPRMTVaenlLVAKFRGE---KRGLIPrHLASYKEEFQTVLAKIGNGLEN-----HIDTAVEFLSGGQ 156
Cdd:PRK09536 75 ASR-----RVASVPQDTS----LSFEFDVRqvvEMGRTP-HRSRFDTWTETDRAAVERAMERtgvaqFADRPVTSLSGGE 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDpkTSQALMTLtdEFVK---QDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:PRK09536 145 RQRVLLARALAQATPVLLLDEPTASLD--INHQVRTL--ELVRrlvDDGKTAVAAIHDLDLAARYCDELVLLADGRV 217
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
4-222 |
2.54e-20 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 86.37 E-value: 2.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGMNEEKvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:PRK10584 6 IVEVHHLKKSVGQGEHELS-ILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR----VFQDPKMgtAPRMTVAENL-LVAKFRGEKRGliprhlaSYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQ 158
Cdd:PRK10584 85 LRAKhvgfVFQSFML--IPTLNALENVeLPALLRGESSR-------QSRNGAKALLEQL--GLGKRLDHLPAQLSGGEQQ 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRL 222
Cdd:PRK10584 154 RVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRL 217
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
5-231 |
2.63e-20 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 85.73 E-value: 2.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVT-NYSPEKRAK 83
Cdd:cd03268 1 LKTNDLTKTYG-----KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQkNIEALRRIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLsrvFQDPkmGTAPRMTVAENLLV-AKFRGEKrgliprhlasyKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQALSL 162
Cdd:cd03268 76 AL---IEAP--GFYPNLTARENLRLlARLLGIR-----------KKRIDEVLDVV--GLKDSAKKKVKGFSLGMKQRLGI 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 163 LMATLKRPELLLLDEHTAALDPK----TSQALMTLTDEfvkqdALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03268 138 ALALLGNPDLLILDEPTNGLDPDgikeLRELILSLRDQ-----GITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
4-238 |
3.21e-20 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 88.93 E-value: 3.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDfitILG-----GNGagKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP 78
Cdd:COG3845 257 VLEVENLSVRDDRG----VPALKDVSLEVRAGE---ILGiagvaGNG--QSELAEALAGLRPPASGSIRLDGEDITGLSP 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 79 EKRAKY-LSRVFQDP-KMGTAPRMTVAENLLVAKFRGE---KRGLIPRHLASYK-----EEFQTVLAkignglenHIDTA 148
Cdd:COG3845 328 RERRRLgVAYIPEDRlGRGLVPDMSVAENLILGRYRRPpfsRGGFLDRKAIRAFaeeliEEFDVRTP--------GPDTP 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 149 VEFLSGG--QRqalsLLMA--TLKRPELLLLDEHTAALDPKTSqalmtltdEFVKQ------DALTA-LMITHHMEDALK 217
Cdd:COG3845 400 ARSLSGGnqQK----VILAreLSRDPKLLIAAQPTRGLDVGAI--------EFIHQrllelrDAGAAvLLISEDLDEILA 467
|
250 260
....*....|....*....|.
gi 1080618511 218 YGNRLIVMKDGHIVQDLNQEE 238
Cdd:COG3845 468 LSDRIAVMYEGRIVGEVPAAE 488
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
5-231 |
3.54e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 87.11 E-value: 3.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:PRK13649 3 INLQNVSYTYQAGTPFEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPkmgtaprmtvaENLLVAKFRGEKRGLIPRHLASYKEEFQTV----LAKIGNGlENHIDTAVEFLSGGQ 156
Cdd:PRK13649 83 IRKkvglVFQFP-----------ESQLFEETVLKDVAFGPQNFGVSQEEAEALarekLALVGIS-ESLFEKNPFELSGGQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 157 --RQALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK13649 151 mrRVAIAGILAM--EPKILVLDEPTAGLDPKGRKELMTLFKK-LHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLV 224
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
5-238 |
3.59e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 87.14 E-value: 3.59e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:PRK13646 3 IRFDNVSYTYQKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPKMGTAPRMTVAENLLvakfrGEKRGLIPrhLASYKEEFQTVLAKIGngLENHIDTAVEF-LSGGQRQA 159
Cdd:PRK13646 83 VRKrigmVFQFPESQLFEDTVEREIIF-----GPKNFKMN--LDEVKNYAHRLLMDLG--FSRDVMSQSPFqMSGGQMRK 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:PRK13646 154 IAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKE 232
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
6-231 |
4.46e-20 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 84.89 E-value: 4.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 6 ELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAG--TLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:cd03217 2 EIKDLHVSV-----GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILFKGEDITDLPPEERAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 ---YLSrvFQDPkmgtaprmtvaenllvakfrgekrgliprhlasykEEFQTVlaKIGNGLENhIDtavEFLSGGQRQAL 160
Cdd:cd03217 77 lgiFLA--FQYP-----------------------------------PEIPGV--KNADFLRY-VN---EGFSGGEKKRN 113
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALD----PKTSQALMTLTDEFVkqdalTALMITHHmEDALKY--GNRLIVMKDGHIV 231
Cdd:cd03217 114 EILQLLLLEPDLAILDEPDSGLDidalRLVAEVINKLREEGK-----SVLIITHY-QRLLDYikPDRVHVLYDGRIV 184
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
21-247 |
4.82e-20 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 84.93 E-value: 4.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSrvfqdPKMGTAPRM 100
Cdd:PRK13539 14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHYLG-----HRNAMKPAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAENLLV-AKFRGEKRGLIPRHLASYkeefqtvlakignGLENHIDTAVEFLSGGQ--RQALSLLMATlKRPeLLLLDE 177
Cdd:PRK13539 89 TVAENLEFwAAFLGGEELDIAAALEAV-------------GLAPLAHLPFGYLSAGQkrRVALARLLVS-NRP-IWILDE 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 178 HTAALDPKTsqalmtltdefvkqDALTALMITHHMEdalkyGNRLIVMKDgHivQDLNQEEKAQMTIADY 247
Cdd:PRK13539 154 PTAALDAAA--------------VALFAELIRAHLA-----QGGIVIAAT-H--IPLGLPGARELDLGPF 201
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
24-232 |
5.54e-20 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 85.67 E-value: 5.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTaprMTVA 103
Cdd:cd03249 18 ILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLVSQEPVLFD---GTIA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLLVAKFRGEKrgliprhlasykEEFQTVlAKIGN------GLENHIDTAVEF----LSGGQRQALSLLMATLKRPELL 173
Cdd:cd03249 95 ENIRYGKPDATD------------EEVEEA-AKKANihdfimSLPDGYDTLVGErgsqLSGGQKQRIAIARALLRNPKIL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 174 LLDEHTAALDPKTsqalmtltdEFVKQDAL-------TALMITHHMEdALKYGNRLIVMKDGHIVQ 232
Cdd:cd03249 162 LLDEATSALDAES---------EKLVQEALdramkgrTTIVIAHRLS-TIRNADLIAVLQNGQVVE 217
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
4-231 |
6.60e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 86.39 E-value: 6.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTL---PVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK13640 5 IVEFKHVSFTYPD---SKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLTAKTVWD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDPK---MGTaprmTVAENllVAkFRGEKRGlIPRhlasykEEFQTVLAKIGN--GLENHIDTAVEFLSGG 155
Cdd:PRK13640 82 IREKVGIVFQNPDnqfVGA----TVGDD--VA-FGLENRA-VPR------PEMIKIVRDVLAdvGMLDYIDSEPANLSGG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDAlKYGNRLIVMKDGHIV 231
Cdd:PRK13640 148 QKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLL 222
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
4-232 |
6.76e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 86.83 E-value: 6.76e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYI---------LGEDVT 74
Cdd:PRK13631 21 ILRVKNLYCVFDEKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyigdkkNNHELI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 75 NYSPE---KRAKYLSR----VFQDPKMGTApRMTVAENLLVAkfrgekrgliPRHLASYKEEFQTVLAKIGNGL---ENH 144
Cdd:PRK13631 101 TNPYSkkiKNFKELRRrvsmVFQFPEYQLF-KDTIEKDIMFG----------PVALGVKKSEAKKLAKFYLNKMgldDSY 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 145 IDTAVEFLSGGQ--RQALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRL 222
Cdd:PRK13631 170 LERSPFGLSGGQkrRVAIAGILAI--QPEILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVADEV 246
|
250
....*....|
gi 1080618511 223 IVMKDGHIVQ 232
Cdd:PRK13631 247 IVMDKGKILK 256
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-233 |
7.31e-20 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 85.83 E-value: 7.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAvsngMNEEKViLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTL---PVSSGKIYILGEDVTNYS 77
Cdd:PRK09984 1 MQTIIRVEKLAKT----FNQHQA-LHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLItgdKSAGSHIELLGRTVQREG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEKRAKYLSR-----VFQdpKMGTAPRMTVAENLLVAKFrgekrGLIP--RHLASY-----KEEFQTVLAKIGNGLENHi 145
Cdd:PRK09984 76 RLARDIRKSRantgyIFQ--QFNLVNRLSVLENVLIGAL-----GSTPfwRTCFSWftreqKQRALQALTRVGMVHFAH- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 146 dTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVM 225
Cdd:PRK09984 148 -QRVSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVAL 226
|
....*...
gi 1080618511 226 KDGHIVQD 233
Cdd:PRK09984 227 RQGHVFYD 234
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
24-232 |
1.12e-19 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 84.96 E-value: 1.12e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTL---FNTIAGTLPVS--SGKIYILGEDVTNYSPEKRAKYLSRVFQDPKmgTAP 98
Cdd:PRK14247 18 VLDGVNLEIPDNTITALMGPSGSGKSTLlrvFNRLIELYPEArvSGEVYLDGQDIFKMDVIELRRRVQMVFQIPN--PIP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 RMTVAENLLVakfrgekrGLIPRHLASYKEEFQTVL------AKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPEL 172
Cdd:PRK14247 96 NLSIFENVAL--------GLKLNRLVKSKKELQERVrwalekAQLWDEVKDRLDAPAGKLSGGQQQRLCIARALAFQPEV 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 173 LLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK14247 168 LLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIVE 225
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-231 |
1.49e-19 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 87.41 E-value: 1.49e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGMneekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK15439 8 APPLLCARSISKQYSGVE-----VLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAK---YLsrVFQDPKMgtAPRMTVAENLLvakFRgekrglIPRHLASYKeEFQTVLAKIGNGLEnhIDTAVEFLSGGQR 157
Cdd:PRK15439 83 AHQlgiYL--VPQEPLL--FPNLSVKENIL---FG------LPKRQASMQ-KMKQLLAALGCQLD--LDSSAGSLEVADR 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK15439 147 QIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQG-VGIVFISHKLPEIRQLADRISVMRDGTIA 219
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
5-233 |
1.78e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 85.52 E-value: 1.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKI-YILGEDVTNYSPEKRAK 83
Cdd:PRK13651 3 IKVKNIVKIFNKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIeWIFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR-VFQDPKM-------GTAPRMTV----AENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIGN--GL-ENHIDTA 148
Cdd:PRK13651 83 VLEKlVIQKTRFkkikkikEIRRRVGVvfqfAEYQLFEQTIEKDIIFGPVSMGVSKEEAKKRAAKYIElvGLdESYLQRS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 149 VEFLSGGQ--RQALSLLMATlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMK 226
Cdd:PRK13651 163 PFELSGGQkrRVALAGILAM--EPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGK-TIILVTHDLDNVLEWTKRTIFFK 239
|
....*..
gi 1080618511 227 DGHIVQD 233
Cdd:PRK13651 240 DGKIIKD 246
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
24-215 |
3.03e-19 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 82.47 E-value: 3.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtNYSPE---KRAKYLSRVFQDPkmgtaprm 100
Cdd:TIGR01166 7 VLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPL-DYSRKgllERRQRVGLVFQDP-------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 tvaENLLVAKFRGEKRGLIPRHLASYKEEFQTV----LAKIG-NGLEnhiDTAVEFLSGGQRQALSLLMATLKRPELLLL 175
Cdd:TIGR01166 78 ---DDQLFAADVDQDVAFGPLNLGLSEAEVERRvreaLTAVGaSGLR---ERPTHCLSGGEKKRVAIAGAVAMRPDVLLL 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1080618511 176 DEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDA 215
Cdd:TIGR01166 152 DEPTAGLDPAGREQMLAILRRLRAE-GMTVVISTHDVDLA 190
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
22-238 |
4.45e-19 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 83.99 E-value: 4.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAG-TLPVS----SGKIYILGEDVTNYSP--EKRAKyLSRVFQDPKm 94
Cdd:PRK14271 34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRmNDKVSgyrySGDVLLGGRSIFNYRDvlEFRRR-VGMLFQRPN- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 gTAPrMTVAENLLvAKFRGEKrgLIPRHlaSYKEEFQTVLAKIG--NGLENHIDTAVEFLSGGQRQALSLLMATLKRPEL 172
Cdd:PRK14271 112 -PFP-MSIMDNVL-AGVRAHK--LVPRK--EFRGVAQARLTEVGlwDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEV 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 173 LLLDEHTAALDPKTSQALmtltDEFVKQ--DALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:PRK14271 185 LLLDEPTSALDPTTTEKI----EEFIRSlaDRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQ 248
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
3-232 |
5.71e-19 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 84.70 E-value: 5.71e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 3 AIVELKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA 82
Cdd:PRK11000 2 ASVTLRNVTKAYG-----DVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 kyLSRVFQDPKMgtAPRMTVAENLLVA-KFRGEKRGLIPRHLASYKEEFQtvlakigngLENHIDTAVEFLSGGQRQALS 161
Cdd:PRK11000 77 --VGMVFQSYAL--YPHLSVAENMSFGlKLAGAKKEEINQRVNQVAEVLQ---------LAHLLDRKPKALSGGQRQRVA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11000 144 IGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQ 214
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-232 |
6.16e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 85.62 E-value: 6.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTK---AVSNGMNEEkviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYI-LGE---DVTNY 76
Cdd:TIGR03269 279 IIKVRNVSKryiSVDRGVVKA---VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrVGDewvDMTKP 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 77 SPEKRA---KYLSRVFQDpkMGTAPRMTVAENLLvakfrgEKRGL-IPRHLASYKEEFqtVLAKIG---NGLENHIDTAV 149
Cdd:TIGR03269 356 GPDGRGrakRYIGILHQE--YDLYPHRTVLDNLT------EAIGLeLPDELARMKAVI--TLKMVGfdeEKAEEILDKYP 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 150 EFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGH 229
Cdd:TIGR03269 426 DELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGK 505
|
...
gi 1080618511 230 IVQ 232
Cdd:TIGR03269 506 IVK 508
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
4-231 |
6.24e-19 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 82.32 E-value: 6.24e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVsNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP---VSSGKIYILGEDVTNYSPEK 80
Cdd:cd03234 3 VLPWWDVGLKA-KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRKPDQFQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSrvfQDPKmgTAPRMTVAENLL-VAKFRGekrgliPRHLASY---KEEFQTVLAKIGNGlenHI-DTAVEFLSGG 155
Cdd:cd03234 82 CVAYVR---QDDI--LLPGLTVRETLTyTAILRL------PRKSSDAirkKRVEDVLLRDLALT---RIgGNLVKGISGG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03234 148 ERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIV 223
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
25-232 |
6.78e-19 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 85.40 E-value: 6.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPkmGTAPRmTVAE 104
Cdd:PRK13657 351 VEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAVVFQDA--GLFNR-SIED 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLLVAKFRGEKRGLiprHLASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDP 184
Cdd:PRK13657 428 NIRVGRPDATDEEM---RAAAERAQAHDFIERKPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILILDEATSALDV 504
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 185 KTSQALmtltdefvkQDALTALM------ITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK13657 505 ETEAKV---------KAALDELMkgrttfIIAHRLSTVRNADRILVFDNGRVVE 549
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
22-233 |
8.53e-19 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 82.81 E-value: 8.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY---LSRVFQDPKMGTAP 98
Cdd:PRK10419 25 QTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQRKAFrrdIQMVFQDSISAVNP 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 RMTVAENLlvakfrGEkrgliP-RHLASYKEEFQtvLAKIGNGLE------NHIDTAVEFLSGGQRQALSLLMATLKRPE 171
Cdd:PRK10419 105 RKTVREII------RE-----PlRHLLSLDKAER--LARASEMLRavdlddSVLDKRPPQLSGGQLQRVCLARALAVEPK 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 172 LLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:PRK10419 172 LLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVET 233
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
24-233 |
1.58e-18 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 84.41 E-value: 1.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAprmTVA 103
Cdd:TIGR01193 489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFINYLPQEPYIFSG---SIL 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLLVakfrGEKRGLIPRHLASYKE--EFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAA 181
Cdd:TIGR01193 566 ENLLL----GAKENVSQDEIWAACEiaEIKDDIENMPLGYQTELSEEGSSISGGQKQRIALARALLTDSKVLILDESTSN 641
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 182 LDPKTSQA----LMTLTDEfvkqdalTALMITHHMEDAlKYGNRLIVMKDGHIVQD 233
Cdd:TIGR01193 642 LDTITEKKivnnLLNLQDK-------TIIFVAHRLSVA-KQSDKIIVLDHGKIIEQ 689
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
25-231 |
1.92e-18 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 82.47 E-value: 1.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSR----VFQDPkmgtaprm 100
Cdd:PRK13643 22 LFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKkvgvVFQFP-------- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 tvaENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAK----IGNGLENHIDTAVEfLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:PRK13643 94 ---ESQLFEETVLKDVAFGPQNFGIPKEKAEKIAAEklemVGLADEFWEKSPFE-LSGGQMRRVAIAGILAMEPEVLVLD 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 177 EHTAALDPKTSQALMTLTdEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK13643 170 EPTAGLDPKARIEMMQLF-ESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHII 223
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
25-232 |
2.19e-18 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 81.51 E-value: 2.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKI-YIL--GEDVTNYS-PEKRAKYLSR-----VFQDPKMG 95
Cdd:PRK11701 22 CRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVhYRMrdGQLRDLYAlSEAERRRLLRtewgfVHQHPRDG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 96 TapRMTV------AENLLVAkfrGEkrglipRHLASYKEEFQTVLAKIGNGLeNHIDTAVEFLSGGQRQALSLLMATLKR 169
Cdd:PRK11701 102 L--RMQVsaggniGERLMAV---GA------RHYGDIRATAGDWLERVEIDA-ARIDDLPTTFSGGMQQRLQIARNLVTH 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 170 PELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11701 170 PRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVE 232
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
5-210 |
2.81e-18 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 79.90 E-value: 2.81e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNG-MNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS--SGKIYILGEDVTNYSPEKR 81
Cdd:cd03213 4 LSFRNLTVTVKSSpSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLgvSGEVLINGRPLDKRSFRKI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AKYlsrVFQDPKmgTAPRMTVAENLLV-AKFRGekrgliprhlasykeefqtvlakignglenhidtavefLSGGQRQAL 160
Cdd:cd03213 84 IGY---VPQDDI--LHPTLTVRETLMFaAKLRG--------------------------------------LSGGERKRV 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVkQDALTALMITH 210
Cdd:cd03213 121 SIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLA-DTGRTIICSIH 169
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-244 |
3.84e-18 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 83.30 E-value: 3.84e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSnGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK09700 2 ATPYISMAGIGKSFG-PVHA----LKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKY-LSRVFQDpkMGTAPRMTVAENLLVAKFRGEKRGLIPrhLASYKE---EFQTVLAKIgnGLENHIDTAVEFLSGGQ 156
Cdd:PRK09700 77 AAQLgIGIIYQE--LSVIDELTVLENLYIGRHLTKKVCGVN--IIDWREmrvRAAMMLLRV--GLKVDLDEKVANLSISH 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGH-----IV 231
Cdd:PRK09700 151 KQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQ-LRKEGTAIVYISHKLAEIRRICDRYTVMKDGSsvcsgMV 229
|
250
....*....|...
gi 1080618511 232 QDLNQEEKAQMTI 244
Cdd:PRK09700 230 SDVSNDDIVRLMV 242
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
25-238 |
4.25e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 81.39 E-value: 4.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKmGTAPRMTVAE 104
Cdd:PRK13652 20 LNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQNPD-DQIFSPTVEQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLlvaKFRGEKRGLIPRHLASYKEEFQTVLakignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDP 184
Cdd:PRK13652 99 DI---AFGPINLGLDEETVAHRVSSALHML-----GLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDP 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 185 KTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:PRK13652 171 QGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEE 224
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-231 |
6.66e-18 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 82.42 E-value: 6.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP----VSSGKIYILGEDVTNY 76
Cdd:COG4172 3 SMPLLSVEDLSVAFGQG-GGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPdpaaHPSGSILFDGQDLLGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 77 SPEK----RAKYLSRVFQDPkMgTA--PRMTV----AENLLV-AKFRGE---KRGL-------IP---RHLASYKEEfqt 132
Cdd:COG4172 82 SERElrriRGNRIAMIFQEP-M-TSlnPLHTIgkqiAEVLRLhRGLSGAaarARALellervgIPdpeRRLDAYPHQ--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 133 vlakignglenhidtavefLSGGQRQALSLLMATLKRPELLLLDEHTAALDPkTSQA-LMTLTDEFVKQDALTALMITH- 210
Cdd:COG4172 157 -------------------LSGGQRQRVMIAMALANEPDLLIADEPTTALDV-TVQAqILDLLKDLQRELGMALLLITHd 216
|
250 260
....*....|....*....|....*.
gi 1080618511 211 -----HMEDalkygnRLIVMKDGHIV 231
Cdd:COG4172 217 lgvvrRFAD------RVAVMRQGEIV 236
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
25-238 |
7.67e-18 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 82.37 E-value: 7.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIR--EhdfitILG--G-NGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK----YLSRvfqDPKM- 94
Cdd:COG1129 268 VRDVSFSVRagE-----ILGiaGlVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDAIRagiaYVPE---DRKGe 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 GTAPRMTVAENLLVAKF-RGEKRGLIPR-----HLASYKEEFQTVLAkignglenHIDTAVEFLSGG--QRQALSLLMAT 166
Cdd:COG1129 340 GLVLDLSIRENITLASLdRLSRGGLLDRrreraLAEEYIKRLRIKTP--------SPEQPVGNLSGGnqQKVVLAKWLAT 411
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 167 lkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:COG1129 412 --DPKVLILDEPTRGIDVGAKAEIYRLIRELAAEG-KAVIVISSELPELLGLSDRILVMREGRIVGELDREE 480
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
21-211 |
8.56e-18 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 78.94 E-value: 8.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDV--TNYSPEKRAKYLSRvfQDpkmGTAP 98
Cdd:TIGR01189 12 ERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLaeQRDEPHENILYLGH--LP---GLKP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 RMTVAENL--LVAKFRGEKRGLiprhlasykeefQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:TIGR01189 87 ELSALENLhfWAAIHGGAQRTI------------EDALAAVG--LTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILD 152
|
170 180 190
....*....|....*....|....*....|....*
gi 1080618511 177 EHTAALDPKTSQALMTLTDEFVKQDALtALMITHH 211
Cdd:TIGR01189 153 EPTTALDKAGVALLAGLLRAHLARGGI-VLLTTHQ 186
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
5-228 |
9.79e-18 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 78.67 E-value: 9.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEdvtnyspekraky 84
Cdd:cd03250 1 ISVEDASFTWDSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtaPRMTVAENLLVAKFRGEKRgliprhlasYKE-----EFQTVLAKIGNGL-----ENHIDtavefLSG 154
Cdd:cd03250 68 IAYVSQEPWI---QNGTIRENILFGKPFDEER---------YEKvikacALEPDLEILPDGDlteigEKGIN-----LSG 130
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMtltDEFVKQDAL---TALMITHHMEdALKYGNRLIVMKDG 228
Cdd:cd03250 131 GQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRHIF---ENCILGLLLnnkTRILVTHQLQ-LLPHADQIVVLDNG 203
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
1-238 |
1.64e-17 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 81.69 E-value: 1.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNgmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpek 80
Cdd:TIGR00958 475 LEGLIEFQDVSFSYPN--RPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYD--- 549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 rAKYLSR----VFQDPKMgtaprmtvaenllvakFRGEKRGLIPRHLASYKEEFQTVLAKIGN------GLENHIDTAV- 149
Cdd:TIGR00958 550 -HHYLHRqvalVGQEPVL----------------FSGSVRENIAYGLTDTPDEEIMAAAKAANahdfimEFPNGYDTEVg 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 150 ---EFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMtltdEFVKQDALTALMITHHMEDALKyGNRLIVMK 226
Cdd:TIGR00958 613 ekgSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQLLQ----ESRSRASRTVLLIAHRLSTVER-ADQILVLK 687
|
250
....*....|..
gi 1080618511 227 DGHIVQDLNQEE 238
Cdd:TIGR00958 688 KGSVVEMGTHKQ 699
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-228 |
2.87e-17 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 77.86 E-value: 2.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKA----VSNGMneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGE----D 72
Cdd:COG4778 1 MTTLLEVENLSKTftlhLQGGK--RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 73 VTNYSP----EKRAK---YLS---RVFqdpkmgtaPRMT----VAENLL-------VAKFRGEK---RGLIPRHLAS-YK 127
Cdd:COG4778 79 LAQASPreilALRRRtigYVSqflRVI--------PRVSaldvVAEPLLergvdreEARARAREllaRLNLPERLWDlPP 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 128 EEFqtvlakignglenhidtaveflSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALM 207
Cdd:COG4778 151 ATF----------------------SGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEA-KARGTAIIG 207
|
250 260
....*....|....*....|.
gi 1080618511 208 ITHHMEDALKYGNRLIVMKDG 228
Cdd:COG4778 208 IFHDEEVREAVADRVVDVTPF 228
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
7-210 |
3.13e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 80.49 E-value: 3.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSngmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlgedvtnySPEKRAKYLS 86
Cdd:COG0488 1 LENLSKSFG-----GRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI--------PKGLRIGYLP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 87 rvfQDPK------------MGTAPRMTVAENLLVAKFRGEKRGLIPRHLASYKEEF------------QTVLAKIGNGLE 142
Cdd:COG0488 68 ---QEPPldddltvldtvlDGDAELRALEAELEELEAKLAEPDEDLERLAELQEEFealggweaearaEEILSGLGFPEE 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 143 NHiDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALmtltDEFVKQDALTALMITH 210
Cdd:COG0488 145 DL-DRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWL----EEFLKNYPGTVLVVSH 207
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
25-238 |
3.78e-17 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 80.22 E-value: 3.78e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSS--GKIYILGEdVTNYSPEKRAKYLSRVFQDPKMGTAPRMTV 102
Cdd:NF040905 17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGE-VCRFKDIRDSEALGIVIIHQELALIPYLSI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 103 AENLLVAKFRGeKRGLIPRHLASykEEFQTVLAKIGngLENHIDTAVEFLSGGQRQ------ALSllmatlKRPELLLLD 176
Cdd:NF040905 96 AENIFLGNERA-KRGVIDWNETN--RRARELLAKVG--LDESPDTLVTDIGVGKQQlveiakALS------KDVKLLILD 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 177 EHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:NF040905 165 EPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRTIETLDCRA 225
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1-236 |
4.94e-17 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 79.96 E-value: 4.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKaVSNGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpeK 80
Cdd:PRK11288 1 SSPYLSFDGIGK-TFPGVKA----LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFAS--T 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRV---FQDpkMGTAPRMTVAENLLVAKFRgEKRGLIPRHLAsyKEEFQTVLAKIGNGLENhiDTAVEFLSGGQR 157
Cdd:PRK11288 74 TAALAAGVaiiYQE--LHLVPEMTVAENLYLGQLP-HKGGIVNRRLL--NYEAREQLEHLGVDIDP--DTPLKYLSIGQR 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQ 236
Cdd:PRK11288 147 QMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRE-LRAEGRVILYVSHRMEEIFALCDAITVFKDGRYVATFDD 224
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
24-234 |
6.00e-17 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 77.16 E-value: 6.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSR----VFQDPKMgtAPR 99
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQklgfIYQFHHL--LPD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 MTVAENLLVAKFRGEKRGliprhlASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHT 179
Cdd:PRK11629 102 FTALENVAMPLLIGKKKP------AEINSRALEMLAAVG--LEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPT 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 180 AALDPKTSQALMTLTDEFVKQDALTALMITHHMEDAlKYGNRLIVMKDGHIVQDL 234
Cdd:PRK11629 174 GNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLA-KRMSRQLEMRDGRLTAEL 227
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
25-230 |
6.30e-17 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 80.06 E-value: 6.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDV-TNYSPEKRAkylsrvfqdpkMGTAPR---- 99
Cdd:TIGR01257 946 VDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLDAVRQS-----------LGMCPQhnil 1014
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 ---MTVAENLLvakFRGEKRGlipRHLASYKEEFQTVLAKigNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:TIGR01257 1015 fhhLTVAEHIL---FYAQLKG---RSWEEAQLEMEAMLED--TGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLD 1086
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 177 EHTAALDPKTSQALMTLTDEFvkQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:TIGR01257 1087 EPTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-232 |
1.12e-16 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 76.71 E-value: 1.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIvELKNVTKAVsNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK11264 1 MSAI-EVKNLVKKF-HG----QTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTARSLS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSR--------VFQDpkMGTAPRMTVAENLLVAKF--RGEKRGliprhlaSYKEEFQTVLAKIGngLENHIDTAVE 150
Cdd:PRK11264 75 QQKGLIRqlrqhvgfVFQN--FNLFPHRTVLENIIEGPVivKGEPKE-------EATARARELLAKVG--LAGKETSYPR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 151 FLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTlTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:PRK11264 144 RLSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLN-TIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRI 222
|
..
gi 1080618511 231 VQ 232
Cdd:PRK11264 223 VE 224
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
4-237 |
1.26e-16 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 76.07 E-value: 1.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpEKRAK 83
Cdd:PRK10908 1 MIRFEHVSKAYLGG----RQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLK-NREVP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSR----VFQDPK--MGTAPRMTVAENLLVAKFRGEKrglIPRHLASykeefqtVLAKIGnglenHIDTAVEF---LSG 154
Cdd:PRK10908 76 FLRRqigmIFQDHHllMDRTVYDNVAIPLIIAGASGDD---IRRRVSA-------ALDKVG-----LLDKAKNFpiqLSG 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDL 234
Cdd:PRK10908 141 GEQQRVGIARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEF-NRVGVTVLMATHDIGLISRRSYRMLTLSDGHLHGGV 219
|
...
gi 1080618511 235 NQE 237
Cdd:PRK10908 220 GGE 222
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-238 |
1.36e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 77.06 E-value: 1.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGMNEEKviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK13642 1 MNKILEVENLVFKYEKESDVNQ--LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDPK---MGTAPRMTVAenllvakFRGEKRGlIPRhlasykeefQTVLAKIGNGL--ENHIDTAVE---FL 152
Cdd:PRK13642 79 LRRKIGMVFQNPDnqfVGATVEDDVA-------FGMENQG-IPR---------EEMIKRVDEALlaVNMLDFKTRepaRL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 153 SGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKyGNRLIVMKDGHIVQ 232
Cdd:PRK13642 142 SGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIK 220
|
....*.
gi 1080618511 233 DLNQEE 238
Cdd:PRK13642 221 EAAPSE 226
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
20-233 |
2.03e-16 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 77.05 E-value: 2.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGedvtnYSP-EKRAKYLSR---VF------ 89
Cdd:COG4586 33 REVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLG-----YVPfKRRKEFARRigvVFgqrsql 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 90 -QDpkmgtaprMTVAE--NLLVAKFRgekrglIPRhlASYKE---EFQTVLakignGLENHIDTAVEFLSGGQRQALSLL 163
Cdd:COG4586 108 wWD--------LPAIDsfRLLKAIYR------IPD--AEYKKrldELVELL-----DLGELLDTPVRQLSLGQRMRCELA 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:COG4586 167 AALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYD 236
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-246 |
2.03e-16 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 78.05 E-value: 2.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSnGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSS--GKIYILGEDVTNYS- 77
Cdd:PRK13549 2 MEYLLEMKNITKTFG-GVKA----LDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTyeGEIIFEGEELQASNi 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEKRAKYLSRVFQDPKMgtAPRMTVAENLlvakFRGEKrgLIPRHLASYKE---EFQTVLAKIgnGLENHIDTAVEFLSG 154
Cdd:PRK13549 77 RDTERAGIAIIHQELAL--VKELSVLENI----FLGNE--ITPGGIMDYDAmylRAQKLLAQL--KLDINPATPVGNLGL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDG-HIvqd 233
Cdd:PRK13549 147 GQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDL-KAHGIACIYISHKLNEVKAISDTICVIRDGrHI--- 222
|
250
....*....|...
gi 1080618511 234 lNQEEKAQMTIAD 246
Cdd:PRK13549 223 -GTRPAAGMTEDD 234
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
5-238 |
2.26e-16 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 78.14 E-value: 2.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNgmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:PRK11176 342 IEFRNVTFTYPG---KEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRV------FQDpkmgtaprmTVAENLLVAKFRGEKRGLIPRHL-ASYKEEFqtvLAKIGNGLENHIDTAVEFLSGGQR 157
Cdd:PRK11176 419 VALVsqnvhlFND---------TIANNIAYARTEQYSREQIEEAArMAYAMDF---INKMDNGLDTVIGENGVLLSGGQR 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDalTALMITHHMEdALKYGNRLIVMKDGHIVQDLNQE 237
Cdd:PRK11176 487 QRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNR--TSLVIAHRLS-TIEKADEILVVEDGEIVERGTHA 563
|
.
gi 1080618511 238 E 238
Cdd:PRK11176 564 E 564
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
5-232 |
3.19e-16 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 77.45 E-value: 3.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAvsngMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:PRK10790 341 IDIDNVSFA----YRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQG 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPkmgtaprMTVAENLLVAKFRGekrglipRHLASYK--EEFQTV-LAKIGNGLENHIDTAV----EFLSGGQR 157
Cdd:PRK10790 417 VAMVQQDP-------VVLADTFLANVTLG-------RDISEEQvwQALETVqLAELARSLPDGLYTPLgeqgNNLSVGQK 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALmtltdefvkQDAL------TALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK10790 483 QLLALARVLVQTPQILILDEATANIDSGTEQAI---------QQALaavrehTTLVVIAHRLSTIVEADTILVLHRGQAV 553
|
.
gi 1080618511 232 Q 232
Cdd:PRK10790 554 E 554
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
5-252 |
4.28e-16 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 77.15 E-value: 4.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGT--LPVSSGK-IYILGedvtnYSPE-K 80
Cdd:TIGR03269 1 IEVKNLTKKF-----DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRiIYHVA-----LCEKcG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQD-PKMGTAPRMTVAE--NLLVAKFRGEKRG---LIPRHLASYKEefQTVLAKIGNGLE-------NHIDT 147
Cdd:TIGR03269 71 YVERPSKVGEPcPVCGGTLEPEEVDfwNLSDKLRRRIRKRiaiMLQRTFALYGD--DTVLDNVLEALEeigyegkEAVGR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 148 AVEF----------------LSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHH 211
Cdd:TIGR03269 149 AVDLiemvqlshrithiardLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHW 228
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1080618511 212 MEDALKYGNRLIVMKDGHIVQDLNQEEkaqmTIADYYELFE 252
Cdd:TIGR03269 229 PEVIEDLSDKAIWLENGEIKEEGTPDE----VVAVFMEGVS 265
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
20-232 |
5.14e-16 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 75.08 E-value: 5.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPV------SSGKIYILGEDVTNYSPEKRAKYLSRVFQDPK 93
Cdd:PRK14246 21 NDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIydskikVDGKVLYFGKDIFQIDAIKLRKEVGMVFQQPN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 mgTAPRMTVAENL---LVAKFRGEKRGLiprhlasyKEEFQTVLAKIGNGLENH--IDTAVEFLSGGQRQALSLLMATLK 168
Cdd:PRK14246 101 --PFPHLSIYDNIaypLKSHGIKEKREI--------KKIVEECLRKVGLWKEVYdrLNSPASQLSGGQQQRLTIARALAL 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 169 RPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK14246 171 KPKVLLMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVE 232
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
25-241 |
6.60e-16 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 76.58 E-value: 6.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK----YLSrvfQDPKM-GTAPR 99
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLAngivYIS---EDRKRdGLVLG 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 MTVAENL-LVAKFRGEKRGLIPRHlasyKEEFQTVLAKIG--NGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:PRK10762 345 MSVKENMsLTALRYFSRAGGSLKH----ADEQQAVSDFIRlfNIKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILD 420
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 177 EHTAALDPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEKAQ 241
Cdd:PRK10762 421 EPTRGVDVGAKKEIYQLINQF-KAEGLSIILVSSEMPEVLGMSDRILVMHEGRISGEFTREQATQ 484
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
21-232 |
7.40e-16 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 76.67 E-value: 7.40e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKST----LFNTIAgtlpvSSGKIYILGEDVTNYSPEKRAKYLSR---VFQDPK 93
Cdd:PRK15134 298 HNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLNRRQLLPVRHRiqvVFQDPN 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 MGTAPRMTV----AENLLVAKfrgekrglipRHLASYKEEFQ--TVLAKIGNGLENHIDTAVEFlSGGQRQALSLLMATL 167
Cdd:PRK15134 373 SSLNPRLNVlqiiEEGLRVHQ----------PTLSAAQREQQviAVMEEVGLDPETRHRYPAEF-SGGQRQRIAIARALI 441
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 168 KRPELLLLDEHTAALDpKTSQA-LMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK15134 442 LKPSLIILDEPTSSLD-KTVQAqILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVE 506
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
2-232 |
7.76e-16 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 76.28 E-value: 7.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVSNGMNEEKVIlDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS-----SGKIYILGEDVTNY 76
Cdd:PRK15134 3 QPLLAIENLSVAFRQQQTVRTVV-NDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPpvvypSGDIRFHGESLLHA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 77 SPEK----RAKYLSRVFQDPKMGTAPRMTVAENL--LVAKFRGEKRgliprhlASYKEEFQTVLAKIGngLENHIDTAVE 150
Cdd:PRK15134 82 SEQTlrgvRGNKIAMIFQEPMVSLNPLHTLEKQLyeVLSLHRGMRR-------EAARGEILNCLDRVG--IRQAAKRLTD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 151 F---LSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKD 227
Cdd:PRK15134 153 YphqLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQN 232
|
....*
gi 1080618511 228 GHIVQ 232
Cdd:PRK15134 233 GRCVE 237
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-210 |
8.55e-16 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 74.38 E-value: 8.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVtkAVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEK 80
Cdd:PRK09544 1 MTSLVSLENV--SVSFG---QRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 rakylsrVFQDPkmgTAPrmtvaenLLVAKFRGEKRGLiprhlasYKEEFQTVLAKIGNGleNHIDTAVEFLSGGQRQAL 160
Cdd:PRK09544 76 -------LYLDT---TLP-------LTVNRFLRLRPGT-------KKEDILPALKRVQAG--HLIDAPMQKLSGGETQRV 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITH 210
Cdd:PRK09544 130 LLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSH 179
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
27-232 |
1.08e-15 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 74.44 E-value: 1.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 27 DVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAPRMTVAENL 106
Cdd:PRK15112 31 PLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSYRSQRIRMIFQDPSTSLNPRQRISQIL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 107 -----LVAKFRGEKRgliprhlasyKEEFQTVLAKIGNgLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAA 181
Cdd:PRK15112 111 dfplrLNTDLEPEQR----------EKQIIETLRQVGL-LPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALAS 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 182 LDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK15112 180 LDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVE 230
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
21-230 |
1.13e-15 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 74.24 E-value: 1.13e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVT---------NYSPEKRAKYL----SR 87
Cdd:PRK10619 17 EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkdgqlKVADKNQLRLLrtrlTM 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 88 VFQDPKMGTapRMTVAENLLVAKFRgekrgLIPRHLASYKEEFQTVLAKIGNGLENHIDTAVEfLSGGQRQALSLLMATL 167
Cdd:PRK10619 97 VFQHFNLWS--HMTVLENVMEAPIQ-----VLGLSKQEARERAVKYLAKVGIDERAQGKYPVH-LSGGQQQRVSIARALA 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 168 KRPELLLLDEHTAALDPKTSQALMTLTDEFVkQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:PRK10619 169 MEPEVLLFDEPTSALDPELVGEVLRIMQQLA-EEGKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
25-231 |
1.90e-15 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 73.34 E-value: 1.90e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPvSSGKIYILGEDVTNYSPE----KRAkYLSRvfQDPkmgTAPRM 100
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAelarHRA-YLSQ--QQS---PPFAM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAENLLVAkfrgekrglIPRHLASykEEFQTVLAKIGN--GLENHIDTAVEFLSGGQRQALsLLMATL--------KRP 170
Cdd:COG4138 85 PVFQYLALH---------QPAGASS--EAVEQLLAQLAEalGLEDKLSRPLTQLSGGEWQRV-RLAAVLlqvwptinPEG 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 171 ELLLLDEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:COG4138 153 QLLLLDEPMNSLDVAQQAALDRLLRELCQQ-GITVVMSSHDLNHTLRHADRVWLLKQGKLV 212
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
20-216 |
1.99e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 72.29 E-value: 1.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnyspEKRAKYLSRV-FQDPKMGTAP 98
Cdd:PRK13540 12 HDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIK----KDLCTYQKQLcFVGHRSGINP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 RMTVAENLlvakfrgekrgLIPRHLASYKEEFqTVLAKIGNgLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEH 178
Cdd:PRK13540 88 YLTLRENC-----------LYDIHFSPGAVGI-TELCRLFS-LEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEP 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 1080618511 179 TAALDPKTSQALMTLTDEFVKQDAltALMITHHMEDAL 216
Cdd:PRK13540 155 LVALDELSLLTIITKIQEHRAKGG--AVLLTSHQDLPL 190
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1-232 |
2.28e-15 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 74.23 E-value: 2.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTK--AVSNGM-NEEKVI--LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTN 75
Cdd:PRK11308 2 QQPLLQAIDLKKhyPVKRGLfKPERLVkaLDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 76 YSPEKRAKYLSR---VFQDPKMGTAPRMTVAENLlvakfrgEKRGLIPRHL--ASYKEEFQTVLAKIGNGLEnHIDTAVE 150
Cdd:PRK11308 82 ADPEAQKLLRQKiqiVFQNPYGSLNPRKKVGQIL-------EEPLLINTSLsaAERREKALAMMAKVGLRPE-HYDRYPH 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 151 FLSGGQRQALSLLMATLKRPELLLLDEHTAALDpKTSQA-----LMTLTDEFvkqdALTALMITH------HMEDalkyg 219
Cdd:PRK11308 154 MFSGGQRQRIAIARALMLDPDVVVADEPVSALD-VSVQAqvlnlMMDLQQEL----GLSYVFISHdlsvveHIAD----- 223
|
250
....*....|...
gi 1080618511 220 nRLIVMKDGHIVQ 232
Cdd:PRK11308 224 -EVMVMYLGRCVE 235
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
12-231 |
2.41e-15 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 74.86 E-value: 2.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 12 KAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQD 91
Cdd:COG5265 361 ENVSFGYDPERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIGIVPQD 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 92 PKMGTAprmTVAENLLVAkfrgekrglipRHLASyKEEFQTV--LAKIG---NGLENHIDTAV-EF---LSGGQRQALSL 162
Cdd:COG5265 441 TVLFND---TIAYNIAYG-----------RPDAS-EEEVEAAarAAQIHdfiESLPDGYDTRVgERglkLSGGEKQRVAI 505
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 163 LMATLKRPELLLLDEHTAALDPKTSQALmtltdefvkQDAL-------TALMITHHME---DAlkygNRLIVMKDGHIV 231
Cdd:COG5265 506 ARTLLKNPPILIFDEATSALDSRTERAI---------QAALrevargrTTLVIAHRLStivDA----DEILVLEAGRIV 571
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
5-230 |
2.71e-15 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 73.30 E-value: 2.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKavSNGMNEekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIaGTLPV-SSGKIYILGEDVtnysPEKRAK 83
Cdd:COG4598 9 LEVRDLHK--SFGDLE---VLKGVSLTARKGDVISIIGSSGSGKSTFLRCI-NLLETpDSGEIRVGGEEI----RLKPDR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSRVFQDPKMGTAPR---------------MTVAENLLVAKFRGEKRgliPRhlASYKEEFQTVLAKIGngLENHIDTA 148
Cdd:COG4598 79 DGELVPADRRQLQRIRtrlgmvfqsfnlwshMTVLENVIEAPVHVLGR---PK--AEAIERAEALLAKVG--LADKRDAY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 149 VEFLSGGQRQ----ALSLLMatlkRPELLLLDEHTAALDPKtsqalmtLTDEFVK------QDALTALMITHHMEDALKY 218
Cdd:COG4598 152 PAHLSGGQQQraaiARALAM----EPEVMLFDEPTSALDPE-------LVGEVLKvmrdlaEEGRTMLVVTHEMGFARDV 220
|
250
....*....|..
gi 1080618511 219 GNRLIVMKDGHI 230
Cdd:COG4598 221 SSHVVFLHQGRI 232
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
24-232 |
3.55e-15 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 74.77 E-value: 3.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAprmTVA 103
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQAPVLFSG---TVR 1330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLlvAKFRGEKRGLIPRHLAsyKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALD 183
Cdd:PLN03130 1331 FNL--DPFNEHNDADLWESLE--RAHLKDVIRRNSLGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVD 1406
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 184 PKTSqALM--TLTDEFvkqDALTALMITHHMEDALKyGNRLIVMKDGHIVQ 232
Cdd:PLN03130 1407 VRTD-ALIqkTIREEF---KSCTMLIIAHRLNTIID-CDRILVLDAGRVVE 1452
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
2-228 |
4.24e-15 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 74.66 E-value: 4.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKaVSNGMNEEKVilDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDV-TNyspek 80
Cdd:TIGR01257 1935 TDILRLNELTK-VYSGTSSPAV--DRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIlTN----- 2006
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 rakyLSRVFQDpkMGTAPRMTVAENLLVAKfrgEKRGLIPRHLASYKEEFQtvlaKIGN------GLENHIDTAVEFLSG 154
Cdd:TIGR01257 2007 ----ISDVHQN--MGYCPQFDAIDDLLTGR---EHLYLYARLRGVPAEEIE----KVANwsiqslGLSLYADRLAGTYSG 2073
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 155 GQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:TIGR01257 2074 GNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGR-AVVLTSHSMEECEALCTRLAIMVKG 2146
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
7-231 |
5.15e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 72.73 E-value: 5.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyILGEDV--TNYSPEKRAKY 84
Cdd:PRK13645 9 LDNVSYTYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQT-IVGDYAipANLKKIKEVKR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSR----VFQDPKMGTApRMTVAENLLVAkfrgekrgliPRHLASYKEE-FQTV--LAKIGNGLENHIDTAVEFLSGGQR 157
Cdd:PRK13645 88 LRKeiglVFQFPEYQLF-QETIEKDIAFG----------PVNLGENKQEaYKKVpeLLKLVQLPEDYVKRSPFELSGGQK 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK13645 157 RRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVI 230
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
38-231 |
5.29e-15 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 73.37 E-value: 5.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 38 IT-ILGGNGAGKSTLFNTIAGTLPVSSGKIyILGEDV-------TNYSPEKRakYLSRVFQDPKMgtAPRMTVAENLL-- 107
Cdd:PRK11144 26 ITaIFGRSGAGKTSLINAISGLTRPQKGRI-VLNGRVlfdaekgICLPPEKR--RIGYVFQDARL--FPHYKVRGNLRyg 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 108 VAKFRgekrgliprhlasyKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTS 187
Cdd:PRK11144 101 MAKSM--------------VAQFDKIVALLG--IEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRK 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1080618511 188 QALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK11144 165 RELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVK 208
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
7-231 |
6.12e-15 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 72.13 E-value: 6.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLS 86
Cdd:PRK10575 14 LRNVSFRVPG-----RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 87 RVFQdpKMGTAPRMTVAEnlLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIGngLENHIDTAVEFLSGGQRQALSLLMAT 166
Cdd:PRK10575 89 YLPQ--QLPAAEGMTVRE--LVAIGRYPWHGALGRFGAADREKVEEAISLVG--LKPLAHRLVDSLSGGERQRAWIAMLV 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 167 LKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK10575 163 AQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
4-230 |
7.79e-15 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 71.35 E-value: 7.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:cd03248 11 IVKFQNVTFAYPT--RPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSRVFQDPKMGTAprmTVAENLlvakfrgeKRGLIPRHLASYKEEFQTVLA-----KIGNGLENHIDTAVEFLSGGQRQ 158
Cdd:cd03248 89 KVSLVGQEPVLFAR---SLQDNI--------AYGLQSCSFECVKEAAQKAHAhsfisELASGYDTEVGEKGSQLSGGQKQ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDalTALMITHHMEdALKYGNRLIVMKDGHI 230
Cdd:cd03248 158 RVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERR--TVLVIAHRLS-TVERADQILVLDGGRI 226
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-231 |
1.66e-14 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 70.84 E-value: 1.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTkaVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTL---FN----TIAGTlpVSSGKIYILGEDV 73
Cdd:COG1117 8 LEPKIEVRNLN--VYYG---DKQALKDINLDIPENKVTALIGPSGCGKSTLlrcLNrmndLIPGA--RVEGEILLDGEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 74 tnYSPEKRAKYLSR----VFQDPkmgtAP-RMTVAENllVA--------KFRGEKRGLIPRHL--ASYKEEFQTVLAKig 138
Cdd:COG1117 81 --YDPDVDVVELRRrvgmVFQKP----NPfPKSIYDN--VAyglrlhgiKSKSELDEIVEESLrkAALWDEVKDRLKK-- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 139 NGLEnhidtavefLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDALKY 218
Cdd:COG1117 151 SALG---------LSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD--YTIVIVTHNMQQAARV 219
|
250
....*....|...
gi 1080618511 219 GNRLIVMKDGHIV 231
Cdd:COG1117 220 SDYTAFFYLGELV 232
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
5-211 |
1.84e-14 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 69.10 E-value: 1.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKraky 84
Cdd:cd03223 1 IELENLSLATPDG----RVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGEDLLFLPQR---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 lsrvfqdPKMgtaPRMTVAENLLvakfrgekrgliprhLASYKEefqtvlakignglenhidtavefLSGGQRQALSLLM 164
Cdd:cd03223 73 -------PYL---PLGTLREQLI---------------YPWDDV-----------------------LSGGEQQRLAFAR 104
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLtdefVKQDALTALMITHH 211
Cdd:cd03223 105 LLLHKPKFVFLDEATSALDEESEDRLYQL----LKELGITVISVGHR 147
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
26-184 |
1.95e-14 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 72.46 E-value: 1.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 26 DDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVT--NYSPEKRAKYLSRVF----Qdpkmgtapr 99
Cdd:NF033858 283 DHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDagDIATRRRVGYMSQAFslygE--------- 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 MTVAENL-LVAKFRGEKRGLIPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEH 178
Cdd:NF033858 354 LTVRQNLeLHARLFHLPAAEIAARVAEMLERF---------DLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEP 424
|
....*.
gi 1080618511 179 TAALDP 184
Cdd:NF033858 425 TSGVDP 430
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
5-193 |
2.09e-14 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 72.15 E-value: 2.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyilgedvtNYSPEKRAKY 84
Cdd:COG4178 363 LALEDLTLRTPDG----RPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRI--------ARPAGARVLF 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSrvfQDPKMgtaPRMTVAENLLVakfrgekrgliPRHLASYK-EEFQTVLAKIGNG-LENHIDTAVEF---LSGGQRQA 159
Cdd:COG4178 431 LP---QRPYL---PLGTLREALLY-----------PATAEAFSdAELREALEAVGLGhLAERLDEEADWdqvLSLGEQQR 493
|
170 180 190
....*....|....*....|....*....|....
gi 1080618511 160 LSLLMATLKRPELLLLDEHTAALDPKTSQALMTL 193
Cdd:COG4178 494 LAFARLLLHKPDWLFLDEATSALDEENEAALYQL 527
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
22-233 |
3.05e-14 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 70.24 E-value: 3.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS--------SGKIYILGEDVTNYSPEKRAKYLSRVFQDPK 93
Cdd:PRK13547 14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPRLARLRAVLPQAAQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 MGTAprMTVAENLLVAKFRGEKRGLIPRHlaSYKEEFQTVLAKIGNGLENHIDtaVEFLSGGQ--RQALSLLMATL---- 167
Cdd:PRK13547 94 PAFA--FSAREIVLLGRYPHARRAGALTH--RDGEIAWQALALAGATALVGRD--VTTLSGGElaRVQFARVLAQLwpph 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 168 ---KRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQD 233
Cdd:PRK13547 168 daaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAH 236
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
3-231 |
3.28e-14 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 69.92 E-value: 3.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 3 AIVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA 82
Cdd:PRK10895 2 ATLTAKNLAKAY-----KGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 K----YL---SRVFQdpkmgtapRMTVAENLL-VAKFR----GEKRGLIPRHLAsykEEFQtvlakigngLENHIDTAVE 150
Cdd:PRK10895 77 RrgigYLpqeASIFR--------RLSVYDNLMaVLQIRddlsAEQREDRANELM---EEFH---------IEHLRDSMGQ 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 151 FLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTdEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHI 230
Cdd:PRK10895 137 SLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRII-EHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHL 215
|
.
gi 1080618511 231 V 231
Cdd:PRK10895 216 I 216
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
26-228 |
4.18e-14 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 70.52 E-value: 4.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 26 DDVSLEIREHDFITILGGNGAGKS-TLFnTIAGTLP---VSSGKIYILGEDVTNYsPEK-----RAKYLSRVFQDPKMGT 96
Cdd:PRK09473 33 NDLNFSLRAGETLGIVGESGSGKSqTAF-ALMGLLAangRIGGSATFNGREILNL-PEKelnklRAEQISMIFQDPMTSL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 APRMTVAENLLVAkfrgekrgLIPRHLASYKEEFQTVL----------AKIGNGLENHidtavEFlSGGQRQALSLLMAT 166
Cdd:PRK09473 111 NPYMRVGEQLMEV--------LMLHKGMSKAEAFEESVrmldavkmpeARKRMKMYPH-----EF-SGGMRQRVMIAMAL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 167 LKRPELLLLDEHTAALDpKTSQA-LMTLTDEfVKQDALTA-LMITHHMEDALKYGNRLIVMKDG 228
Cdd:PRK09473 177 LCRPKLLIADEPTTALD-VTVQAqIMTLLNE-LKREFNTAiIMITHDLGVVAGICDKVLVMYAG 238
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
24-232 |
4.27e-14 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 70.70 E-value: 4.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP----VSSGKIYILGEDVTNYSPEKRAKYLSR----VFQDPKMG 95
Cdd:COG4170 22 AVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLLKLSPRERRKIIGReiamIFQEPSSC 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 96 TAPRMTVAENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIgnGLENHIDTAVEF---LSGGQRQALSLLMATLKRPEL 172
Cdd:COG4170 102 LDPSAKIGDQLIEAIPSWTFKGKWWQRFKWRKKRAIELLHRV--GIKDHKDIMNSYpheLTEGECQKVMIAMAIANQPRL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 173 LLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:COG4170 180 LIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVE 239
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
28-231 |
7.58e-14 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 68.81 E-value: 7.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 28 VSLEIREHDFITILGGNGAGKSTLFNTIAGTLPvSSGKIYILGEDVTNYSPEKRAK---YLSRvfQDPkmgTAPRMTVAE 104
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSAAELARhraYLSQ--QQT---PPFAMPVFQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLlvAKFRGEKRGLiprhlasykEEFQTVLAKIGN--GLENHIDTAVEFLSGGQRQALSLLMATLK-----RPE--LLLL 175
Cdd:PRK03695 89 YL--TLHQPDKTRT---------EAVASALNEVAEalGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvwpdiNPAgqLLLL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 176 DEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK03695 158 DEPMNSLDVAQQAALDRLLSELCQQ-GIAVVMSSHDLNHTLRHADRVWLLKQGKLL 212
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
21-231 |
8.09e-14 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 69.02 E-value: 8.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP----EKRAKyLSRVFQDPKMGT 96
Cdd:PRK11831 19 NRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRsrlyTVRKR-MSMLFQSGALFT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 apRMTVAENllVAKFRGEKRGLIPRHLASykeefqTVLAKI-GNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLL 175
Cdd:PRK11831 98 --DMNVFDN--VAYPLREHTQLPAPLLHS------TVMMKLeAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMF 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 176 DEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK11831 168 DEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIV 223
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
7-183 |
9.43e-14 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 70.46 E-value: 9.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 7 LKNVTKAVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP---VSSGKIYILGEDVTNYSPEKRAK 83
Cdd:TIGR00955 23 LVSRLRGCFCRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPkgvKGSGSVLLNGMPIDAKEMRAISA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YlsrVFQDPKMgtAPRMTVAENLLV-AKFRgekrglIPRHLaSYKEEFQTVLAKIGN-GLENHIDT------AVEFLSGG 155
Cdd:TIGR00955 103 Y---VQQDDLF--IPTLTVREHLMFqAHLR------MPRRV-TKKEKRERVDEVLQAlGLRKCANTrigvpgRVKGLSGG 170
|
170 180
....*....|....*....|....*...
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALD 183
Cdd:TIGR00955 171 ERKRLAFASELLTDPPLLFCDEPTSGLD 198
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-210 |
1.17e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 69.96 E-value: 1.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlgedvtnySPEKRAK 83
Cdd:TIGR03719 4 IYTMNRVSKVVPPK----KEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARP--------QPGIKVG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 YLSrvfQDPKMGtaPRMTVAENllVAKFRGEKRGLIPRH------LASYKEEFQTVLAKIGNgLENHIDTA--------- 148
Cdd:TIGR03719 72 YLP---QEPQLD--PTKTVREN--VEEGVAEIKDALDRFneisakYAEPDADFDKLAAEQAE-LQEIIDAAdawdldsql 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 149 ---------------VEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALmtltDEFVKQDALTALMITH 210
Cdd:TIGR03719 144 eiamdalrcppwdadVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWL----ERHLQEYPGTVVAVTH 216
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
24-238 |
1.42e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 70.00 E-value: 1.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAprmTVA 103
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQSPVLFSG---TVR 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLlvAKFRGEKRGLIPRHLasYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALD 183
Cdd:PLN03232 1328 FNI--DPFSEHNDADLWEAL--ERAHIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVD 1403
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 184 PKTSQALM-TLTDEFvkqDALTALMITHHMEDALKYgNRLIVMKDGHIVQDLNQEE 238
Cdd:PLN03232 1404 VRTDSLIQrTIREEF---KSCTMLVIAHRLNTIIDC-DKILVLSSGQVLEYDSPQE 1455
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
5-210 |
1.70e-13 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 65.93 E-value: 1.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyilgedvtnyspekraky 84
Cdd:cd03221 1 IELENLSKTY-----GGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV------------------ 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 lsrvfqdpkmgtaprmTVAENLLVAKFRgekrgliprhlasykeefQtvlakignglenhidtavefLSGGQRQALSLLM 164
Cdd:cd03221 58 ----------------TWGSTVKIGYFE------------------Q--------------------LSGGEKMRLALAK 83
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALmtltDEFVKQDALTALMITH 210
Cdd:cd03221 84 LLLENPNLLLLDEPTNHLDLESIEAL----EEALKEYPGTVILVSH 125
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
21-232 |
2.58e-13 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 67.49 E-value: 2.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTI--AGTL-P--VSSGKIYILGEDVtnYSP-----EKRaKYLSRVFQ 90
Cdd:PRK14239 17 KKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLnPevTITGSIVYNGHNI--YSPrtdtvDLR-KEIGMVFQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 91 DPKmgTAPrMTVAENLLVA-KFRGEKrgliPRHLASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKR 169
Cdd:PRK14239 94 QPN--PFP-MSIYENVVYGlRLKGIK----DKQVLDEAVEKSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARVLATS 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 170 PELLLLDEHTAALDP----KTSQALMTLTDEFvkqdalTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK14239 167 PKIILLDEPTSALDPisagKIEETLLGLKDDY------TMLLVTRSMQQASRISDRTGFFLDGDLIE 227
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
24-210 |
3.22e-13 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 67.17 E-value: 3.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS-----SGKIYILGEDVtnYSPEKRA----KYLSRVFQDPKm 94
Cdd:PRK14267 19 VIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNI--YSPDVDPievrREVGMVFQYPN- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 gTAPRMTVAENLLVakfrgekrGLIPRHLASYKEEFQTVL------AKIGNGLENHIDTAVEFLSGGQRQALSLLMATLK 168
Cdd:PRK14267 96 -PFPHLTIYDNVAI--------GVKLNGLVKSKKELDERVewalkkAALWDEVKDRLNDYPSNLSGGQRQRLVIARALAM 166
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1080618511 169 RPELLLLDEHTAALDPKTSQALMTLTDEFvkQDALTALMITH 210
Cdd:PRK14267 167 KPKILLMDEPTANIDPVGTAKIEELLFEL--KKEYTIVLVTH 206
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
4-246 |
4.29e-13 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 68.31 E-value: 4.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSS--GKIYILGEDVTNYS-PEK 80
Cdd:TIGR02633 1 LLEMKGIVKTFGG-----VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASNiRDT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDpkMGTAPRMTVAENLLVAKFRGEKRGLIprHLASYKEEFQTVLAKIGNGLENhIDTAVEFLSGGQRQAL 160
Cdd:TIGR02633 76 ERAGIVIIHQE--LTLVPELSVAENIFLGNEITLPGGRM--AYNAMYLRAKNLLRELQLDADN-VTRPVGDYGGGQQQLV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGhivQDLNQEEKA 240
Cdd:TIGR02633 151 EIAKALNKQARLLILDEPSSSLTEKETEILLDIIRD-LKAHGVACVYISHKLNEVKAVCDTICVIRDG---QHVATKDMS 226
|
....*.
gi 1080618511 241 QMTIAD 246
Cdd:TIGR02633 227 TMSEDD 232
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
5-241 |
6.31e-13 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 67.69 E-value: 6.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAvsngMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:PRK10522 323 LELRNVTFA----YQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRKL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGT---APRMTVAENLLVAKFrgekrglIPRHLASYKEEFQtvlakiGNGLENhIDtavefLSGGQRQALS 161
Cdd:PRK10522 399 FSAVFTDFHLFDqllGPEGKPANPALVEKW-------LERLKMAHKLELE------DGRISN-LK-----LSKGQKKRLA 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHhmEDA-LKYGNRLIVMKDGHIvQDLNQEEKA 240
Cdd:PRK10522 460 LLLALAEERDILLLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISH--DDHyFIHADRLLEMRNGQL-SELTGEERD 536
|
.
gi 1080618511 241 Q 241
Cdd:PRK10522 537 A 537
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
4-244 |
6.69e-13 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 67.65 E-value: 6.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTkaVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP-VSSGKIYILGEDVTNYSPEKRA 82
Cdd:PRK13549 259 ILEVRNLT--AWDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRNPQQAI 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 KY-LSRVFQDPKM-GTAPRMTVAENLLVAKF-RGEKRGLI--PRHLASYKEEFQTVLAKIGnglenHIDTAVEFLSGGQR 157
Cdd:PRK13549 337 AQgIAMVPEDRKRdGIVPVMGVGKNITLAALdRFTGGSRIddAAELKTILESIQRLKVKTA-----SPELAIARLSGGNQ 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQE 237
Cdd:PRK13549 412 QKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEGKLKGDLINH 490
|
....*..
gi 1080618511 238 EKAQMTI 244
Cdd:PRK13549 491 NLTQEQV 497
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
4-210 |
8.62e-13 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 67.45 E-value: 8.62e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEirehdF-----ITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlgedvtnySP 78
Cdd:PRK11819 6 IYTMNRVSKVVPPK----KQILKDISLS-----FfpgakIGVLGLNGAGKSTLLRIMAGVDKEFEGEARP--------AP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 79 EKRAKYLSrvfQDPKMGtaPRMTVAENllVAKFRGEKRGLIPRH------LASYKEEFQTVLAKIGNgLENHIDTA---- 148
Cdd:PRK11819 69 GIKVGYLP---QEPQLD--PEKTVREN--VEEGVAEVKAALDRFneiyaaYAEPDADFDALAAEQGE-LQEIIDAAdawd 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 149 --------------------VEFLSGGQRQ--ALSLLMatLKRPELLLLDEHTAALDPKTSQALmtltDEFVKQDALTAL 206
Cdd:PRK11819 141 ldsqleiamdalrcppwdakVTKLSGGERRrvALCRLL--LEKPDMLLLDEPTNHLDAESVAWL----EQFLHDYPGTVV 214
|
....
gi 1080618511 207 MITH 210
Cdd:PRK11819 215 AVTH 218
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
25-232 |
3.29e-12 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 65.15 E-value: 3.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP----VSSGKIYILGEDVTNYSPEKRAKY----LSRVFQDPKMGT 96
Cdd:PRK11022 23 VDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRISEKERRNLvgaeVAMIFQDPMTSL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 APRMTVAENLLVA-KFR--GEKRGLIPRHLasykeefqTVLAKIG-NGLENHIDTAVEFLSGGQRQALSLLMATLKRPEL 172
Cdd:PRK11022 103 NPCYTVGFQIMEAiKVHqgGNKKTRRQRAI--------DLLNQVGiPDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKL 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 173 LLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK11022 175 LIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVE 234
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
24-212 |
3.95e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 64.29 E-value: 3.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLF------NTIAGTLPVSsGKIYILGEDVTnyspEKRA------KYLSRVFqd 91
Cdd:PRK14258 22 ILEGVSMEIYQSKVTAIIGPSGCGKSTFLkclnrmNELESEVRVE-GRVEFFNQNIY----ERRVnlnrlrRQVSMVH-- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 92 PKMGTAPrMTVAENLLVA-KFRG-----EKRGLIPRHLASykeefqtvlAKIGNGLENHIDTAVEFLSGGQRQALSLLMA 165
Cdd:PRK14258 95 PKPNLFP-MSVYDNVAYGvKIVGwrpklEIDDIVESALKD---------ADLWDEIKHKIHKSALDLSGGQQQRLCIARA 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1080618511 166 TLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHM 212
Cdd:PRK14258 165 LAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNL 211
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
5-230 |
4.49e-12 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 65.74 E-value: 4.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNeekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:TIGR00957 1285 VEFRNYCLRYREDLD---LVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFK 1361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMgtaprmtvaenllvakFRGEKR-GLIPrhLASYKEE----------FQTVLAKIGNGLENHIDTAVEFLS 153
Cdd:TIGR00957 1362 ITIIPQDPVL----------------FSGSLRmNLDP--FSQYSDEevwwalelahLKTFVSALPDKLDHECAEGGENLS 1423
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1080618511 154 GGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALM-TLTDEFvkqDALTALMITHHMEDALKYgNRLIVMKDGHI 230
Cdd:TIGR00957 1424 VGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQsTIRTQF---EDCTVLTIAHRLNTIMDY-TRVIVLDKGEV 1497
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
42-184 |
4.93e-12 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 63.33 E-value: 4.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 42 GGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVfqdpkMGTAPRMTVAENLlvaKFRGEKRGLIPR 121
Cdd:PRK13543 44 GDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMAYLGHL-----PGLKADLSTLENL---HFLCGLHGRRAK 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 122 HLASykeefqTVLAKIgnGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDP 184
Cdd:PRK13543 116 QMPG------SALAIV--GLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
4-247 |
5.38e-12 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 65.19 E-value: 5.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTkavsnGMNEEKVilDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP----E 79
Cdd:PRK09700 265 VFEVRNVT-----SRDRKKV--RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPldavK 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKYLSRVFQD----PKMGTAPRMTVAENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIGNGLENHIDTavefLSGG 155
Cdd:PRK09700 338 KGMAYITESRRDngffPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQRELLALKCHSVNQNITE----LSGG 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDL- 234
Cdd:PRK09700 414 NQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQ-LADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILt 492
|
250
....*....|...
gi 1080618511 235 NQEEKAQMTIADY 247
Cdd:PRK09700 493 NRDDMSEEEIMAW 505
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
21-211 |
6.40e-12 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 62.90 E-value: 6.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDpkmGTAPRM 100
Cdd:cd03231 12 GRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAP---GIKTTL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAENLlvakfrgekRGLIPRHlasYKEEFQTVLAKIG-NGLEnhiDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHT 179
Cdd:cd03231 89 SVLENL---------RFWHADH---SDEQVEEALARVGlNGFE---DRPVAQLSAGQQRRVALARLLLSGRPLWILDEPT 153
|
170 180 190
....*....|....*....|....*....|..
gi 1080618511 180 AALDPKTSQALMTLTDEFVKQDALtALMITHH 211
Cdd:cd03231 154 TALDKAGVARFAEAMAGHCARGGM-VVLTTHQ 184
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
22-232 |
7.65e-12 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 63.57 E-value: 7.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLP----VSSGKIYILGEDVtnySPEK-RAKYLSRVFQDPKMGT 96
Cdd:PRK10418 16 QPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPagvrQTAGRVLLDGKPV---APCAlRGRKIATIMQNPRSAF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 APRMTVAENllvAKFRGEKRGlIPRHLASYKEEFQTVlakignGLEN--HIDTAVEF-LSGGQRQALSLLMATLKRPELL 173
Cdd:PRK10418 93 NPLHTMHTH---ARETCLALG-KPADDATLTAALEAV------GLENaaRVLKLYPFeMSGGMLQRMMIALALLCEAPFI 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 174 LLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK10418 163 IADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVE 221
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
20-211 |
1.02e-11 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 62.13 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnyspEKRAKYLSRVF----QDpkmG 95
Cdd:PRK13538 12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIR----RQRDEYHQDLLylghQP---G 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 96 TAPRMTVAENLLVAKfrgekrgliprHLASYKEEFQT--VLAKIgnGLENHIDTAVEFLSGGQ--RQALSLLMatLKRPE 171
Cdd:PRK13538 85 IKTELTALENLRFYQ-----------RLHGPGDDEALweALAQV--GLAGFEDVPVRQLSAGQqrRVALARLW--LTRAP 149
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1080618511 172 LLLLDEHTAALDPKTSQALMTLTDEFVKQDALtALMITHH 211
Cdd:PRK13538 150 LWILDEPFTAIDKQGVARLEALLAQHAEQGGM-VILTTHQ 188
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
4-241 |
1.22e-11 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 64.08 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTkaVSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS-SGKIYILGEDVTNYSPEK-- 80
Cdd:TIGR02633 257 ILEARNLT--CWDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDIRNPAQai 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKyLSRVFQDPKM-GTAPRMTVAENLLVA---KFRGEKRGLIPRHLASYKEEFQTVLAKIGnglenHIDTAVEFLSGGQ 156
Cdd:TIGR02633 335 RAG-IAMVPEDRKRhGIVPILGVGKNITLSvlkSFCFKMRIDAAAELQIIGSAIQRLKVKTA-----SPFLPIGRLSGGN 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVkQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQ 236
Cdd:TIGR02633 409 QQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLA-QEGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGDFVN 487
|
....*
gi 1080618511 237 EEKAQ 241
Cdd:TIGR02633 488 HALTQ 492
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
25-215 |
1.62e-11 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 62.49 E-value: 1.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTL---FNTIAGTLPV--SSGKIYILGEDVtnYSPEKRAKYLSR----VFQDPKmg 95
Cdd:PRK14243 26 VKNVWLDIPKNQITAFIGPSGCGKSTIlrcFNRLNDLIPGfrVEGKVTFHGKNL--YAPDVDPVEVRRrigmVFQKPN-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 96 TAPRmTVAENLL----VAKFRGEKRGLIPRHL--ASYKEEFQTVLAKigNGLEnhidtavefLSGGQRQALSLLMATLKR 169
Cdd:PRK14243 102 PFPK-SIYDNIAygarINGYKGDMDELVERSLrqAALWDEVKDKLKQ--SGLS---------LSGGQQQRLCIARAIAVQ 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1080618511 170 PELLLLDEHTAALDPKTSQALMTLTDEFVKQdaLTALMITHHMEDA 215
Cdd:PRK14243 170 PEVILMDEPCSALDPISTLRIEELMHELKEQ--YTIIIVTHNMQQA 213
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
25-224 |
1.83e-11 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 62.04 E-value: 1.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDF-----ITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnYSPEK-RAKYLSRVfqdpkmgtap 98
Cdd:cd03237 10 LGEFTLEVEGGSIsesevIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-YKPQYiKADYEGTV---------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 rmtvaENLLvakfrgekRGLIPRHLASykEEFQTVLAKiGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEH 178
Cdd:cd03237 79 -----RDLL--------SSITKDFYTH--PYFKTEIAK-PLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEP 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1080618511 179 TAALDpkTSQALMT--LTDEFVKQDALTALMITH--HMEDALkyGNRLIV 224
Cdd:cd03237 143 SAYLD--VEQRLMAskVIRRFAENNEKTAFVVEHdiIMIDYL--ADRLIV 188
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
20-183 |
1.84e-11 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 63.75 E-value: 1.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSS--GKIYILGEDVTnyspEKRAKYLSRVFQDPKMgtA 97
Cdd:PLN03211 79 QERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPT----KQILKRTGFVTQDDIL--Y 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 98 PRMTVAENLL-VAKFRgekrglIPRHLASYKEEF--QTVLAKIG-NGLENHI--DTAVEFLSGGQRQALSLLMATLKRPE 171
Cdd:PLN03211 153 PHLTVRETLVfCSLLR------LPKSLTKQEKILvaESVISELGlTKCENTIigNSFIRGISGGERKRVSIAHEMLINPS 226
|
170
....*....|..
gi 1080618511 172 LLLLDEHTAALD 183
Cdd:PLN03211 227 LLILDEPTSGLD 238
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
25-228 |
1.95e-11 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 63.21 E-value: 1.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtNYSPEKRA--KYLSRVFQDpkMGTAPRMTV 102
Cdd:PRK10982 14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI-DFKSSKEAleNGISMVHQE--LNLVLQRSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 103 AENLLVAKFrgEKRGLIPRHLASYKEEfqtvlAKIGNGLENHID--TAVEFLSGGQRQALSLLMATLKRPELLLLDEHTA 180
Cdd:PRK10982 91 MDNMWLGRY--PTKGMFVDQDKMYRDT-----KAIFDELDIDIDprAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTS 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1080618511 181 ALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDG 228
Cdd:PRK10982 164 SLTEKEVNHLFTIIRK-LKERGCGIVYISHKMEEIFQLCDEITILRDG 210
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-210 |
3.16e-11 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 62.65 E-value: 3.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyILGEDVTnyspekrak 83
Cdd:TIGR03719 322 VIEAENLTKAF-----GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTI-EIGETVK--------- 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 yLSRVFQDpKMGTAPRMTVAEN-------LLVAKFRGEKRGLIPRHlaSYKEEFQTvlAKIGNglenhidtavefLSGGQ 156
Cdd:TIGR03719 387 -LAYVDQS-RDALDPNKTVWEEisggldiIKLGKREIPSRAYVGRF--NFKGSDQQ--KKVGQ------------LSGGE 448
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 157 RQALSLLMaTLKRP-ELLLLDEHTAALDPKTSQALMTLTDEFvkqdALTALMITH 210
Cdd:TIGR03719 449 RNRVHLAK-TLKSGgNVLLLDEPTNDLDVETLRALEEALLNF----AGCAVVISH 498
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
21-231 |
4.23e-11 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 60.74 E-value: 4.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYI------LGEDVT-------NYSPEKRAKYLSR 87
Cdd:COG2401 42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVdvpdnqFGREASlidaigrKGDFKDAVELLNA 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 88 VfqdpKMGTAPRMtvaenllvakfrgekrgliprhLASYKEefqtvlakignglenhidtavefLSGGQRQALSLLMATL 167
Cdd:COG2401 122 V----GLSDAVLW----------------------LRRFKE-----------------------LSTGQKFRFRLALLLA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 168 KRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHME--DALKYGNRLIVMKDGHIV 231
Cdd:COG2401 153 ERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDviDDLQPDLLIFVGYGGVPE 218
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
25-228 |
7.85e-11 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 60.04 E-value: 7.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIY---ILGEDVTNYSPEKRAKY-LSRVFQDPKMGTAprm 100
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHwsnKNESEPSFEATRSRNRYsVAYAAQKPWLLNA--- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAENLLVAKfrgekrgliPRHLASYKE-----EFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLL 175
Cdd:cd03290 94 TVEENITFGS---------PFNKQRYKAvtdacSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 176 DEHTAALDPKTSQALMTL-TDEFVKQDALTALMITHHMEdALKYGNRLIVMKDG 228
Cdd:cd03290 165 DDPFSALDIHLSDHLMQEgILKFLQDDKRTLVLVTHKLQ-YLPHADWIIAMKDG 217
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
17-232 |
9.61e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 61.58 E-value: 9.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 17 GMNEEKVILDDVSleirehDFITILGGNGAGKSTLFNtiagtlpvSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGT 96
Cdd:PTZ00265 1244 GDEEQNVGMKNVN------EFSLTKEGGSGEDSTVFK--------NSGKILLDGVDICDYNLKDLRNLFSIVSQEPMLFN 1309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 aprMTVAENLlvaKFRGEKRGLIPRHLASYKEEFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:PTZ00265 1310 ---MSIYENI---KFGKEDATREDVKRACKFAAIDEFIESLPNKYDTNVGPYGKSLSGGQKQRIAIARALLREPKILLLD 1383
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 177 EHTAALDpKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVM----KDGHIVQ 232
Cdd:PTZ00265 1384 EATSSLD-SNSEKLIEKTIVDIKDKADKTIITIAHRIASIKRSDKIVVFnnpdRTGSFVQ 1442
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
16-232 |
1.58e-10 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 60.64 E-value: 1.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 16 NGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKrAKYLSR----VFQD 91
Cdd:PRK10261 331 NRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGK-LQALRRdiqfIFQD 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 92 PKMGTAPRMTVA----ENLLV--------AKFRG----EKRGLIPRHLASYKEEFqtvlakignglenhidtaveflSGG 155
Cdd:PRK10261 410 PYASLDPRQTVGdsimEPLRVhgllpgkaAAARVawllERVGLLPEHAWRYPHEF----------------------SGG 467
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 156 QRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:PRK10261 468 QRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVE 544
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
25-230 |
2.07e-10 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 60.52 E-value: 2.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNyspekrAKYLSRVfqdpkmgtAPR---M- 100
Cdd:NF033858 17 LDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD------ARHRRAV--------CPRiayMp 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 -----------TVAENL-----LVAKFRGEKRGLIPRHLASykeefqTvlakignGLENHIDTAVEFLSGGQRQALSLLM 164
Cdd:NF033858 83 qglgknlyptlSVFENLdffgrLFGQDAAERRRRIDELLRA------T-------GLAPFADRPAGKLSGGMKQKLGLCC 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 165 ATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQ-DALTALMITHHMEDALKYgNRLIVMKDGHI 230
Cdd:NF033858 150 ALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAErPGMSVLVATAYMEEAERF-DWLVAMDAGRV 215
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
4-231 |
3.22e-10 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 58.88 E-value: 3.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNgmNEekvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAG--TLPVSSGKIYILGEDVTNYSPEKR 81
Cdd:CHL00131 7 ILEIKNLHASVNE--NE---ILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESILDLEPEER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 AK---YLSrvFQDPKmgTAPRMTVAENLLVA-----KFRGEKRgLIPRhlasykeEFQTVLAKIGN--GLENH-IDTAV- 149
Cdd:CHL00131 82 AHlgiFLA--FQYPI--EIPGVSNADFLRLAynskrKFQGLPE-LDPL-------EFLEIINEKLKlvGMDPSfLSRNVn 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 150 EFLSGGQRQALSLLMATLKRPELLLLDEHTAALDpktSQALMTLTDEF--VKQDALTALMITHHmEDALKY--GNRLIVM 225
Cdd:CHL00131 150 EGFSGGEKKRNEILQMALLDSELAILDETDSGLD---IDALKIIAEGInkLMTSENSIILITHY-QRLLDYikPDYVHVM 225
|
....*.
gi 1080618511 226 KDGHIV 231
Cdd:CHL00131 226 QNGKII 231
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
25-238 |
3.56e-10 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 59.05 E-value: 3.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAG----TLPVSSGKIYILGEDVTNYSPEKRAKY----LSRVFQDPKMGT 96
Cdd:PRK15093 23 VDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGvtkdNWRVTADRMRFDDIDLLRLSPRERRKLvghnVSMIFQEPQSCL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 97 APRMTVAENLLVA------------KFRGEKRGLIprhlasykEEFQTVlakignGLENHIDTAVEF---LSGGQRQALS 161
Cdd:PRK15093 103 DPSERVGRQLMQNipgwtykgrwwqRFGWRKRRAI--------ELLHRV------GIKDHKDAMRSFpyeLTEGECQKVM 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:PRK15093 169 IAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKE 245
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
20-191 |
7.93e-10 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 59.02 E-value: 7.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYilgedvtnysPEKRAKYlsrVFQDPKMGTApr 99
Cdd:PTZ00243 671 EPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVW----------AERSIAY---VPQQAWIMNA-- 735
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 mTVAENLLvakFRGEKRgliPRHLASYKE--EFQTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDE 177
Cdd:PTZ00243 736 -TVRGNIL---FFDEED---AARLADAVRvsQLEADLAQLGGGLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDD 808
|
170
....*....|....
gi 1080618511 178 HTAALDPKTSQALM 191
Cdd:PTZ00243 809 PLSALDAHVGERVV 822
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
21-243 |
1.25e-09 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 58.19 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAprm 100
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSD--- 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAENLLVAKfrgekrgliPrhlASYKEEFQTVlAKIGN------GLENHIDTAVE----FLSGGQRQALSLLMATLKRP 170
Cdd:PRK10789 404 TVANNIALGR---------P---DATQQEIEHV-ARLASvhddilRLPQGYDTEVGergvMLSGGQKQRISIARALLLNA 470
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 171 ELLLLDEHTAALDPKTSQALMTLTDEFVKQdalTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEKAQMT 243
Cdd:PRK10789 471 EILILDDALSAVDGRTEHQILHNLRQWGEG---RTVIISAHRLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
20-200 |
1.83e-09 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 56.94 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVtNYSpeKRA-----KYLSRVFQDPKM 94
Cdd:PRK13638 12 QDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPL-DYS--KRGllalrQQVATVFQDPEQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 95 G---TAPRMTVAenllvakFRGEKRGLIPRHLASYKEEFQTVLAKignglENHIDTAVEFLSGGQRQALSLLMATLKRPE 171
Cdd:PRK13638 89 QifyTDIDSDIA-------FSLRNLGVPEAEITRRVDEALTLVDA-----QHFRHQPIQCLSHGQKKRVAIAGALVLQAR 156
|
170 180
....*....|....*....|....*....
gi 1080618511 172 LLLLDEHTAALDPKTSQALMTLTDEFVKQ 200
Cdd:PRK13638 157 YLLLDEPTAGLDPAGRTQMIAIIRRIVAQ 185
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
4-197 |
2.24e-09 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 57.27 E-value: 2.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IV-ELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRA 82
Cdd:PRK11147 318 IVfEMENVNYQI-----DGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTKLEVAYFDQHRA 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 83 KYlsrvfqDPKmgtaprMTVAENLLVAKFRGEKRGlIPRHLASYKEE--FQTVLAKignglenhidTAVEFLSGGQRQAL 160
Cdd:PRK11147 393 EL------DPE------KTVMDNLAEGKQEVMVNG-RPRHVLGYLQDflFHPKRAM----------TPVKALSGGERNRL 449
|
170 180 190
....*....|....*....|....*....|....*..
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEF 197
Cdd:PRK11147 450 LLARLFLKPSNLLILDEPTNDLDVETLELLEELLDSY 486
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
153-238 |
3.08e-09 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 56.67 E-value: 3.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 153 SGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKqDALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:NF000106 146 SGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVR-DGATVLLTTQYMEEAEQLAHELTVIDRGRVIA 224
|
....*.
gi 1080618511 233 DLNQEE 238
Cdd:NF000106 225 DGKVDE 230
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
27-245 |
6.10e-09 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 55.83 E-value: 6.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 27 DVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK----YL------SRVFQD-PKMG 95
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQRLArglvYLpedrqsSGLYLDaPLAW 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 96 TAPRMTVAENLLVAKfRGEKRGLIPRHLASYKEEFqtvlakigngleNHIDTAVEFLSGGQRQALSLLMATLKRPELLLL 175
Cdd:PRK15439 361 NVCALTHNRRGFWIK-PARENAVLERYRRALNIKF------------NHAEQAARTLSGGNQQKVLIAKCLEASPQLLIV 427
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 176 DEHTAALDPKTSQALMTLTDEFVKQDaLTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEKAQMTIA 245
Cdd:PRK15439 428 DEPTRGVDVSARNDIYQLIRSIAAQN-VAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAAINVDTIM 496
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
19-232 |
6.70e-09 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 54.91 E-value: 6.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 19 NEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMGTAp 98
Cdd:cd03288 31 NNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSG- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 rmTVAENLLVAKFRGEKRGLIPRHLASYKeefqTVLAKIGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEH 178
Cdd:cd03288 110 --SIRFNLDPECKCTDDRLWEALEIAQLK----NMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEA 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 179 TAALDPKTSQALM-TLTDEFVKQDALTALMITHHMEDAlkygNRLIVMKDGHIVQ 232
Cdd:cd03288 184 TASIDMATENILQkVVMTAFADRTVVTIAHRVSTILDA----DLVLVLSRGILVE 234
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
4-210 |
7.52e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 55.51 E-value: 7.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlGEDVTnyspekrak 83
Cdd:PRK11819 324 VIEAENLSKSF-----GDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETVK--------- 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 yLSRVFQDpKMGTAPRMTV-------AENLLVAKFRGEKRGLIPRhlasykeeF-------QTvlaKIGNglenhidtav 149
Cdd:PRK11819 389 -LAYVDQS-RDALDPNKTVweeisggLDIIKVGNREIPSRAYVGR--------FnfkggdqQK---KVGV---------- 445
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 150 efLSGGQRQALSLLMaTLKRP-ELLLLDEHTAALDPKTSQALMTLTDEFvkqdALTALMITH 210
Cdd:PRK11819 446 --LSGGERNRLHLAK-TLKQGgNVLLLDEPTNDLDVETLRALEEALLEF----PGCAVVISH 500
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
4-244 |
7.71e-09 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 55.51 E-value: 7.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTkavsnGMNEEKVilDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAK 83
Cdd:PRK10982 250 ILEVRNLT-----SLRQPSI--RDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAIN 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 Y-LSRVFQDPK-MGTAPRMTVAENLLVAKFRGEKRGLIPRHLASYKEEFQTVLAKIGNGLENHiDTAVEFLSGGQRQALS 161
Cdd:PRK10982 323 HgFALVTEERRsTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGH-RTQIGSLSGGNQQKVI 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEKAQ 241
Cdd:PRK10982 402 IGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDK-GIIIISSEMPELLGITDRILVMSNGLVAGIVDTKTTTQ 480
|
...
gi 1080618511 242 MTI 244
Cdd:PRK10982 481 NEI 483
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
1-226 |
8.83e-09 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 54.89 E-value: 8.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNyspEK 80
Cdd:PRK15056 3 QQAGIVVNDVTVTWRNG----HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ---AL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 81 RAKYLSRVFQDPKMGTAPRMTVAENLLVAKFrgEKRGLIPRHLASYKEEFQTVLAKIgnGLENHIDTAVEFLSGGQRQAL 160
Cdd:PRK15056 76 QKNLVAYVPQSEEVDWSFPVLVEDVVMMGRY--GHMGWLRRAKKRDRQIVTAALARV--DMVEFRHRQIGELSGGQKKRV 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 161 SLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMK 226
Cdd:PRK15056 152 FLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRE-LRDEGKTMLVSTHNLGSVTEFCDYTVMVK 216
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
20-249 |
1.06e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 55.50 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 20 EEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAG--TLPVSSGKIYILGEDVTNYSPEKRAKYLSRvfQDPKMGTA 97
Cdd:TIGR00956 774 EKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAErvTTGVITGGDRLVNGRPLDSSFQRSIGYVQQ--QDLHLPTS 851
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 98 prmTVAENLlvaKFRGEKRglIPRHLASY-KEEFQTVLAKIgNGLENHIDTAV----EFLSGGQRQALSLLMATLKRPEL 172
Cdd:TIGR00956 852 ---TVRESL---RFSAYLR--QPKSVSKSeKMEYVEEVIKL-LEMESYADAVVgvpgEGLNVEQRKRLTIGVELVAKPKL 922
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 173 LL-LDEHTAALDPKTSQALMTLTDEFVkqDALTALMITHHMEDALKYG--NRLIVMKDGHIV---QDLNQEEKaqmTIAD 246
Cdd:TIGR00956 923 LLfLDEPTSGLDSQTAWSICKLMRKLA--DHGQAILCTIHQPSAILFEefDRLLLLQKGGQTvyfGDLGENSH---TIIN 997
|
...
gi 1080618511 247 YYE 249
Cdd:TIGR00956 998 YFE 1000
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
23-228 |
1.08e-08 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 55.56 E-value: 1.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 23 VILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMgtaprmtv 102
Cdd:PTZ00243 1324 LVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQDPVL-------- 1395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 103 aenllvakFRGEKRGLIPRHLASYKEEFQTVLAKIGngLENH-------IDTAVefLSGG------QRQALSLLMATLKR 169
Cdd:PTZ00243 1396 --------FDGTVRQNVDPFLEASSAEVWAALELVG--LRERvasesegIDSRV--LEGGsnysvgQRQLMCMARALLKK 1463
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 170 PE-LLLLDEHTAALDP---KTSQAlmTLTDEFvkqDALTALMITHHMEDALKYgNRLIVMKDG 228
Cdd:PTZ00243 1464 GSgFILMDEATANIDPaldRQIQA--TVMSAF---SAYTVITIAHRLHTVAQY-DKIIVMDHG 1520
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
24-197 |
1.10e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 55.34 E-value: 1.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyILGEDVTnyspekrakyLSRVFQDPkmgtaPRmtvA 103
Cdd:PRK11147 18 LLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRI-IYEQDLI----------VARLQQDP-----PR---N 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLLVAKFRGEkrGLipRHLASYKEEFQTVLAKIG---------------------NG--LENHI-----------DTAV 149
Cdd:PRK11147 79 VEGTVYDFVAE--GI--EEQAEYLKRYHDISHLVEtdpseknlnelaklqeqldhhNLwqLENRInevlaqlgldpDAAL 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1080618511 150 EFLSGG-QRQAlSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEF 197
Cdd:PRK11147 155 SSLSGGwLRKA-ALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTF 202
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
24-231 |
1.24e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 55.11 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS----SGKIYILGEDVTNYSPEKRAKYLSRVFQDPKMgtaPR 99
Cdd:TIGR00956 76 ILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFhigvEGVITYDGITPEEIKKHYRGDVVYNAETDVHF---PH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 100 MTVAENL-LVAKFRG-EKRG-LIPRHlaSYKEEFQTVLAKIgNGLENHIDTAV--EFL---SGGQRQALSLLMATLKRPE 171
Cdd:TIGR00956 153 LTVGETLdFAARCKTpQNRPdGVSRE--EYAKHIADVYMAT-YGLSHTRNTKVgnDFVrgvSGGERKRVSIAEASLGGAK 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 172 LLLLDEHTAALDPKTS----QALMTLTDeFVKQDALTAlmITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:TIGR00956 230 IQCWDNATRGLDSATAlefiRALKTSAN-ILDTTPLVA--IYQCSQDAYELFDKVIVLYEGYQI 290
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
25-224 |
1.27e-08 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 54.81 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSL-----EIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIlgeDVT-NYSPEkrakYLSrvfqdpkmgTAP 98
Cdd:PRK13409 350 LGDFSLeveggEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDP---ELKiSYKPQ----YIK---------PDY 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 RMTVAENLlvakfrgekRGLIPRHLASYkeeFQTVLAKiGNGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEH 178
Cdd:PRK13409 414 DGTVEDLL---------RSITDDLGSSY---YKSEIIK-PLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEP 480
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 179 TAALDP----KTSQALMTLTDEFVKqdalTALMITH--HMEDALkyGNRLIV 224
Cdd:PRK13409 481 SAHLDVeqrlAVAKAIRRIAEEREA----TALVVDHdiYMIDYI--SDRLMV 526
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
4-210 |
1.61e-08 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 54.75 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVSNGmneeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPekrak 83
Cdd:TIGR00954 451 GIKFENIPLVTPNG----DVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVP----- 521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 84 ylsrvfQDPKMGtapRMTVAENLLV--AKFRGEKRGLIPRHLASYKEEFQ-TVLAKIGNGLENHIDTAvEFLSGGQRQAL 160
Cdd:TIGR00954 522 ------QRPYMT---LGTLRDQIIYpdSSEDMKRRGLSDKDLEQILDNVQlTHILEREGGWSAVQDWM-DVLSGGEKQRI 591
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 161 SllMATL--KRPELLLLDEHTAALDPKTSQALMTLTDEFvkqdALTALMITH 210
Cdd:TIGR00954 592 A--MARLfyHKPQFAILDECTSAVSVDVEGYMYRLCREF----GITLFSVSH 637
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
2-231 |
1.98e-08 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 53.04 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 2 TAIVELKNVTKAVSNGMNEEKvILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS---SGKIYILGEDVTNYSP 78
Cdd:cd03233 1 ASTLSWRNISFTTGKGRSKIP-ILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 79 EKRAKYLSRVFQDPKMgtaPRMTVAENLlvaKFRGEKRGliprhlasykeefqtvlakignglenhiDTAVEFLSGGQRQ 158
Cdd:cd03233 80 KYPGEIIYVSEEDVHF---PTLTVRETL---DFALRCKG----------------------------NEFVRGISGGERK 125
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 159 ALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALM-ITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:cd03233 126 RVSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVsLYQASDEIYDLFDKVLVLYEGRQI 199
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
4-183 |
2.17e-08 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 53.26 E-value: 2.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 4 IVELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGT--LPVSSGKIYILGEDVTNYSPEKR 81
Cdd:PRK09580 1 MLSIKDLHVSV-----EDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDLLELSPEDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 82 A-KYLSRVFQDPKM--GTAPRMTVAENL-LVAKFRGEKrGLIPRHLASYKEEFQTVLAKIGNGLENHIDTAvefLSGGQR 157
Cdd:PRK09580 76 AgEGIFMAFQYPVEipGVSNQFFLQTALnAVRSYRGQE-PLDRFDFQDLMEEKIALLKMPEDLLTRSVNVG---FSGGEK 151
|
170 180
....*....|....*....|....*..
gi 1080618511 158 QALSLL-MATLKrPELLLLDEHTAALD 183
Cdd:PRK09580 152 KRNDILqMAVLE-PELCILDESDSGLD 177
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
5-215 |
2.42e-08 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 54.25 E-value: 2.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTkaVSNGmneEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIL-------GEdvTNYS 77
Cdd:PRK10938 261 IVLNNGV--VSYN---DRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLfgrrrgsGE--TIWD 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 78 PEKRAKYLS-RVFQDPKMGTAPRmtvaeNLLVAKFRgEKRGLIP------RHLAsykEEFQTVLakignGLENHI-DTAV 149
Cdd:PRK10938 334 IKKHIGYVSsSLHLDYRVSTSVR-----NVILSGFF-DSIGIYQavsdrqQKLA---QQWLDIL-----GIDKRTaDAPF 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 150 EFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDA 215
Cdd:PRK10938 400 HSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDA 465
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
27-238 |
4.31e-08 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 53.32 E-value: 4.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 27 DVSLEIREHDFITILGGNGAGKST-------LFNTIAGTlpVSSGKIYI---------LGEDVTNYSPEKRAKYLSRVFQ 90
Cdd:PRK10261 34 NLSFSLQRGETLAIVGESGSGKSVtalalmrLLEQAGGL--VQCDKMLLrrrsrqvieLSEQSAAQMRHVRGADMAMIFQ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 91 DPKMGTAPRMTV----AENLLVAKFRGEKRGLIP--RHLASYK-EEFQTVLAKIGNGLenhidtaveflSGGQRQALSLL 163
Cdd:PRK10261 112 EPMTSLNPVFTVgeqiAESIRLHQGASREEAMVEakRMLDQVRiPEAQTILSRYPHQL-----------SGGMRQRVMIA 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 164 MATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEE 238
Cdd:PRK10261 181 MALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQ 255
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-242 |
6.12e-08 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 52.70 E-value: 6.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKAVSnGMNEekviLDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSP-E 79
Cdd:PRK10762 1 MQALLQLKGIDKAFP-GVKA----LSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPkS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKYLSRVFQDpkMGTAPRMTVAENLLVAKFRGEKRGLIprhlaSYKEEFQ---TVLAKIgnGLENHIDTAVEFLSGGQ 156
Cdd:PRK10762 76 SQEAGIGIIHQE--LNLIPQLTIAENIFLGREFVNRFGRI-----DWKKMYAeadKLLARL--NLRFSSDKLVGELSIGE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 157 RQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEfVKQDALTALMITHHMEDALKYGNRLIVMKDGHI-----V 231
Cdd:PRK10762 147 QQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRE-LKSQGRGIVYISHRLKEIFEICDDVTVFRDGQFiaereV 225
|
250
....*....|.
gi 1080618511 232 QDLNQEEKAQM 242
Cdd:PRK10762 226 ADLTEDSLIEM 236
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
5-231 |
6.64e-08 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 52.59 E-value: 6.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVsngmnEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyilgedvtNYSPEKRAKY 84
Cdd:PRK15064 320 LEVENLTKGF-----DNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV--------KWSENANIGY 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSrvfQDPKMGTAPRMTVAEnlLVAKFRGEK------RGLIPRHLASykeefqtvlakignglENHIDTAVEFLSGGQ-- 156
Cdd:PRK15064 387 YA---QDHAYDFENDLTLFD--WMSQWRQEGddeqavRGTLGRLLFS----------------QDDIKKSVKVLSGGEkg 445
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 157 RQALSLLMatLKRPELLLLDEHTAALDPKTSQALMTLTDEFvkqdALTALMITHHMEDALKYGNRLIVMKDGHIV 231
Cdd:PRK15064 446 RMLFGKLM--MQKPNVLVMDEPTNHMDMESIESLNMALEKY----EGTLIFVSHDREFVSSLATRIIEITPDGVV 514
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
25-183 |
7.12e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.86 E-value: 7.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSL-----EIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYilgEDVT-NYSPEkrakYLSRVFQdpkmgtap 98
Cdd:COG1245 351 YGGFSLeveggEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVD---EDLKiSYKPQ----YISPDYD-------- 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 99 rMTVAENLlvakfrgekRGLIPRHLAS--YKEEFQTVLakignGLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:COG1245 416 -GTVEEFL---------RSANTDDFGSsyYKTEIIKPL-----GLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLD 480
|
....*..
gi 1080618511 177 EHTAALD 183
Cdd:COG1245 481 EPSAHLD 487
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
14-190 |
7.41e-08 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 52.86 E-value: 7.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 14 VSNGMNEeKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLsRVFQDPK 93
Cdd:PRK10636 318 VSAGYGD-RIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEFL-RADESPL 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 MG---TAPRMT---VAENLLVAKFRGEKrgliprhlasykeefqtvlakignglenhIDTAVEFLSGGQRQALSLLMATL 167
Cdd:PRK10636 396 QHlarLAPQELeqkLRDYLGGFGFQGDK-----------------------------VTEETRRFSGGEKARLVLALIVW 446
|
170 180
....*....|....*....|...
gi 1080618511 168 KRPELLLLDEHTAALDPKTSQAL 190
Cdd:PRK10636 447 QRPNLLLLDEPTNHLDLDMRQAL 469
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
24-228 |
9.88e-08 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 51.78 E-value: 9.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyilgedvtnyspekraKYLSRVFQDPKMGTAPRMTVA 103
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI----------------KHSGRISFSSQFSWIMPGTIK 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLLVAKFRGEKRGL-------IPRHLASYKEEFQTVLAKIGNGlenhidtavefLSGGQRQALSLLMATLKRPELLLLD 176
Cdd:cd03291 116 ENIIFGVSYDEYRYKsvvkacqLEEDITKFPEKDNTVLGEGGIT-----------LSGGQRARISLARAVYKDADLYLLD 184
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 177 EHTAALDpktsqalmTLTDEFVKQDALTALM-------ITHHMEDaLKYGNRLIVMKDG 228
Cdd:cd03291 185 SPFGYLD--------VFTEKEIFESCVCKLManktrilVTSKMEH-LKKADKILILHEG 234
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
28-241 |
1.13e-07 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 52.11 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 28 VSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTnysPEKRAKYLSR---VFQDPKmgtaprmtVAE 104
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVT---ADNREAYRQLfsaVFSDFH--------LFD 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLLvakfrGEKRGLIPRHLASYKEEFQtvlakignglenhIDTAVEF---------LSGGQRQALSLLMATL-KRPeLLL 174
Cdd:COG4615 420 RLL-----GLDGEADPARARELLERLE-------------LDHKVSVedgrfsttdLSQGQRKRLALLVALLeDRP-ILV 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 175 LDEHTAALDPktsqalmtltdEF-----------VKQDALTALMITH-----HMEDalkygnRLIVMKDGHIVQDLNQEE 238
Cdd:COG4615 481 FDEWAADQDP-----------EFrrvfytellpeLKARGKTVIAISHddryfDLAD------RVLKMDYGKLVELTGPAA 543
|
...
gi 1080618511 239 KAQ 241
Cdd:COG4615 544 LAA 546
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
1-71 |
1.55e-07 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 50.97 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 1 MTAIVELKNVTKA---------------VSNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGK 65
Cdd:PRK13546 1 MNVSVNIKNVTKEyriyrtnkermkdalIPKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGK 80
|
....*.
gi 1080618511 66 IYILGE 71
Cdd:PRK13546 81 VDRNGE 86
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
24-229 |
2.52e-07 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 51.45 E-value: 2.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIyilgedvtnyspekraKYLSRVFQDPKMGTAPRMTVA 103
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI----------------KHSGRISFSPQTSWIMPGTIK 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 104 ENLLVAKFRGEKRGL-------IPRHLASYKEEFQTVLAKIGNGLenhidtaveflSGGQRQALSLLMATLKRPELLLLD 176
Cdd:TIGR01271 505 DNIIFGLSYDEYRYTsvikacqLEEDIALFPEKDKTVLGEGGITL-----------SGGQRARISLARAVYKDADLYLLD 573
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 177 EHTAALDpktsqalmTLTDEFVKQDALTALM-------ITHHMEDaLKYGNRLIVMKDGH 229
Cdd:TIGR01271 574 SPFTHLD--------VVTEKEIFESCLCKLMsnktrilVTSKLEH-LKKADKILLLHEGV 624
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
152-227 |
6.53e-07 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 50.03 E-value: 6.53e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1080618511 152 LSGGQRQALSLLMATLKRPELLLLDEHTAALDPKtSQALMTLTDEFVKQDALTALMITHHMEDALKYGNRLIVMKD 227
Cdd:PTZ00265 580 LSGGQKQRISIARAIIRNPKILILDEATSSLDNK-SEYLVQKTINNLKGNENRITIIIAHRLSTIRYANTIFVLSN 654
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
8-228 |
1.00e-06 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 48.01 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 8 KNVTKAVsNGMNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAG--TLPVSSGKIYILGedvtnyspEKRAKYL 85
Cdd:cd03232 7 KNLNYTV-PVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILING--------RPLDKNF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 86 SRVfqdpkMGTAPRM-------TVAENLLV-AKFRGekrgliprhlasykeefqtvlakignglenhidtavefLSGGQR 157
Cdd:cd03232 78 QRS-----TGYVEQQdvhspnlTVREALRFsALLRG--------------------------------------LSVEQR 114
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1080618511 158 QALSLLMATLKRPELLLLDEHTAALDPKTSQALMtltdEFVKQDALTALMI--THHM--EDALKYGNRLIVMKDG 228
Cdd:cd03232 115 KRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIV----RFLKKLADSGQAIlcTIHQpsASIFEKFDRLLLLKRG 185
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
25-254 |
1.03e-06 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 49.12 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 25 LDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGedvtnyspekrakylSRVFQDPKMGTAPRMTVAE 104
Cdd:PRK13545 40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG---------------SAALIAISSGLNGQLTGIE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 105 NLlvakfrgEKRGLIprhLASYKEEFQTVLAKIGNGLE--NHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAAL 182
Cdd:PRK13545 105 NI-------ELKGLM---MGLTKEKIKEIIPEIIEFADigKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVG 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1080618511 183 DPKTSQALMTLTDEFvKQDALTALMITHHMEDALKYGNRLIVMKDGHIVQ--DLNQeekaqmtIADYYELFEKE 254
Cdd:PRK13545 175 DQTFTKKCLDKMNEF-KEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEygDIKE-------VVDHYDEFLKK 240
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
5-232 |
1.36e-06 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 48.31 E-value: 1.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 5 VELKNVTKAVSNGMNeekVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPvSSGKIYILGEDVTNYSPEKRAKY 84
Cdd:cd03289 3 MTVKDLTAKYTEGGN---AVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPLQKWRKA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 85 LSRVFQDPKMGTAP-RMTVAENllvAKFRGEKrgliprhLASYKEE--FQTVLAKIGNGLENHIDTAVEFLSGGQRQALS 161
Cdd:cd03289 79 FGVIPQKVFIFSGTfRKNLDPY---GKWSDEE-------IWKVAEEvgLKSVIEQFPGQLDFVLVDGGCVLSHGHKQLMC 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 162 LLMATLKRPELLLLDEHTAALDPKTSQAL-MTLTDEFvkqdALTALMITHHMEDALKYGNRLIVMKDGHIVQ 232
Cdd:cd03289 149 LARSVLSKAKILLLDEPSAHLDPITYQVIrKTLKQAF----ADCTVILSEHRIEAMLECQRFLVIEENKVRQ 216
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
22-251 |
3.06e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 47.98 E-value: 3.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 22 KVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAgTLPVSSGKIYILGEDVTNYSPEKRAKylsrvfqdpKMGTAPRMt 101
Cdd:TIGR01271 1232 RAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALL-RLLSTEGEIQIDGVSWNSVTLQTWRK---------AFGVIPQK- 1300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 vaenllVAKFRGEKRGLIPRHLASYKEEFQTVLAKIG-----NGLENHIDTAVE----FLSGGQRQALSLLMATLKRPEL 172
Cdd:TIGR01271 1301 ------VFIFSGTFRKNLDPYEQWSDEEIWKVAEEVGlksviEQFPDKLDFVLVdggyVLSNGHKQLMCLARSILSKAKI 1374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 173 LLLDEHTAALDPKTSQAL-MTLTDEFVKqdaLTALMITHHMEDALKYGNRLIV----MKDGHIVQDLNQEE---KAQMTI 244
Cdd:TIGR01271 1375 LLLDEPSAHLDPVTLQIIrKTLKQSFSN---CTVILSEHRVEALLECQQFLVIegssVKQYDSIQKLLNETslfKQAMSA 1451
|
....*..
gi 1080618511 245 ADYYELF 251
Cdd:TIGR01271 1452 ADRLKLF 1458
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
29-209 |
3.68e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 44.24 E-value: 3.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 29 SLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSPEKRAKYLSRVFQD-------PKMGTAPRmT 101
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKLVSDEWQRnntdmlsPGEDDTGR-T 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 102 VAENLLvakfRGEKRgliPRHLASYKEEFqtvlakignGLENHIDTAVEFLSGGQ-RQALsLLMATLKRPELLLLDEHTA 180
Cdd:PRK10938 102 TAEIIQ----DEVKD---PARCEQLAQQF---------GITALLDRRFKYLSTGEtRKTL-LCQALMSEPDLLILDEPFD 164
|
170 180
....*....|....*....|....*....
gi 1080618511 181 ALDPKTSQALMTLTDEFVKQDALTALMIT 209
Cdd:PRK10938 165 GLDVASRQQLAELLASLHQSGITLVLVLN 193
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
40-183 |
1.04e-04 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 42.10 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 40 ILGGNGAGKSTLFNTIA----GTLP--VSSGKIYILGEDVTNYSPEKRAKYLSRVFQDPKmgTAPRMTVAENLLVAKFRG 113
Cdd:pfam13476 23 ITGPNGSGKTTILDAIKlalyGKTSrlKRKSGGGFVKGDIRIGLEGKGKAYVEITFENND--GRYTYAIERSRELSKKKG 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1080618511 114 EKRGLIPRHLASYKEEFQTVLAKIGNgleNHIDTAVEFLSGGQRQALSLLMATLKRPELL--LLDEHTAALD 183
Cdd:pfam13476 101 KTKKKEILEILEIDELQQFISELLKS---DKIILPLLVFLGQEREEEFERKEKKERLEELekALEEKEDEKK 169
|
|
| ABC_SMC2_euk |
cd03273 |
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of ... |
18-188 |
1.28e-04 |
|
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213240 [Multi-domain] Cd Length: 251 Bit Score: 42.28 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 18 MNEEKVILD-----DVSLEIREHD--FITILGGNGAGKSTLFNTIAGTLPVSSGK----------IYILG-EDVTNYSPE 79
Cdd:cd03273 1 MHIKEIILDgfksyATRTVISGFDpqFNAITGLNGSGKSNILDAICFVLGITNLStvrasnlqdlIYKRGqAGITKASVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 80 KRAKYLSRVFQDPKMGTAPRMTVAENLLVAkfrGEKRGLIPRHLAS---YKEEFQTVLAKIGNG----LENHI------- 145
Cdd:cd03273 81 IVFDNSDKSQSPIGFENYPEITVTRQIVLG---GTNKYLINGHRAQqqrVQDLFQSVQLNVNNPhfliMQGRItkvlnmg 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1080618511 146 ----DTAVEfLSGGQRQ--ALSLLMATLK-RPE-LLLLDEHTAALDPKTSQ 188
Cdd:cd03273 158 gvwkESLTE-LSGGQRSlvALSLILALLLfKPApMYILDEVDAALDLSHTQ 207
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
18-217 |
1.31e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 41.78 E-value: 1.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 18 MNEEKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYILGEDVTNYSpekrAKYLSRVFQDpkMGTA 97
Cdd:PRK13541 9 FNIEQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIA----KPYCTYIGHN--LGLK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 98 PRMTVAENLlvaKFRGEkrgliprhlasYKEEFQTVLAKIGN-GLENHIDTAVEFLSGGQRQ--ALSLLMATlkRPELLL 174
Cdd:PRK13541 83 LEMTVFENL---KFWSE-----------IYNSAETLYAAIHYfKLHDLLDEKCYSLSSGMQKivAIARLIAC--QSDLWL 146
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1080618511 175 LDEHTAALDPKTSQALMTLTdeFVKQDALTALMITHHMEDALK 217
Cdd:PRK13541 147 LDEVETNLSKENRDLLNNLI--VMKANSGGIVLLSSHLESSIK 187
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
152-210 |
1.56e-04 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 41.19 E-value: 1.56e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1080618511 152 LSGGQRQ--ALSLLM--ATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDAlTALMITH 210
Cdd:cd03227 78 LSGGEKElsALALILalASLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGA-QVIVITH 139
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
40-229 |
4.76e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 40.28 E-value: 4.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 40 ILGGNGAGKSTLFNTIA----GTLPVSSGKIYILGEDVTnySPEKRAK-YLS-RVFQDPKMGTAPRMTVAENLLVAKfRG 113
Cdd:cd03240 27 IVGQNGAGKTTIIEALKyaltGELPPNSKGGAHDPKLIR--EGEVRAQvKLAfENANGKKYTITRSLAILENVIFCH-QG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 114 EKRGLIPRHLasykeefqtvlakignglenhidtavEFLSGGQRQALSLL------MATLKRPELLLLDEHTAALDP-KT 186
Cdd:cd03240 104 ESNWPLLDMR--------------------------GRCSGGEKVLASLIirlalaETFGSNCGILALDEPTTNLDEeNI 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1080618511 187 SQALMTLTDEFVKQDALTALMITHHmEDALKYGNRLI-VMKDGH 229
Cdd:cd03240 158 EESLAEIIEERKSQKNFQLIVITHD-EELVDAADHIYrVEKDGR 200
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
21-244 |
6.56e-04 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 40.54 E-value: 6.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 21 EKVILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTlpvS-----SGKIYILGEDV-TNYSPEKRAKYLSRVFQDPK- 93
Cdd:NF040905 272 ERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGR---SygrniSGTVFKDGKEVdVSTVSDAIDAGLAYVTEDRKg 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 MGTAPRMTVAENLLVAKFRG-EKRGLIPRHlASYK--EEFQ--------TVLAKIGNglenhidtavefLSGGQRQALSL 162
Cdd:NF040905 349 YGLNLIDDIKRNITLANLGKvSRRGVIDEN-EEIKvaEEYRkkmniktpSVFQKVGN------------LSGGNQQKVVL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 163 ---LMAtlkRPELLLLDEHTAALDPKTSQALMTLTDEFVKQdALTALMITHHMEDALKYGNRLIVMKDGHIVQDLNQEEK 239
Cdd:NF040905 416 skwLFT---DPDVLILDEPTRGIDVGAKYEIYTIINELAAE-GKGVIVISSELPELLGMCDRIYVMNEGRITGELPREEA 491
|
....*
gi 1080618511 240 AQMTI 244
Cdd:NF040905 492 SQERI 496
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
152-219 |
2.10e-03 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 38.21 E-value: 2.10e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 152 LSGGQRQ--ALSLLMATLK-RPE-LLLLDEHTAALDPKTSQALMTLTDEFVKQDALtaLMITHH---ME--DALkYG 219
Cdd:cd03278 114 LSGGEKAltALALLFAIFRvRPSpFCVLDEVDAALDDANVERFARLLKEFSKETQF--IVITHRkgtMEaaDRL-YG 187
|
|
| ABC_SMC_head |
cd03239 |
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ... |
150-202 |
2.52e-03 |
|
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.
Pssm-ID: 213206 [Multi-domain] Cd Length: 178 Bit Score: 37.67 E-value: 2.52e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1080618511 150 EFLSGGQRQ--ALSLLMA--TLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDA 202
Cdd:cd03239 93 QILSGGEKSlsALALIFAlqEIKPSPFYVLDEIDAALDPTNRRRVSDMIKEMAKHTS 149
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
24-207 |
5.26e-03 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 37.90 E-value: 5.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 24 ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTLPVS---SGKIYILGEDVTNYSPEKRAKYLSRvfQDPKMGTaprM 100
Cdd:PLN03140 180 ILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSlkvSGEITYNGYRLNEFVPRKTSAYISQ--NDVHVGV---M 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 101 TVAE---------------NLLVAKFRGEK-RGLIPR------HLASYKEEFQTVLA-----KIgNGLENHIDTAV--EF 151
Cdd:PLN03140 255 TVKEtldfsarcqgvgtryDLLSELARREKdAGIFPEaevdlfMKATAMEGVKSSLItdytlKI-LGLDICKDTIVgdEM 333
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1080618511 152 L---SGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTLTDEFVKQDALTALM 207
Cdd:PLN03140 334 IrgiSGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLM 392
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
17-191 |
6.80e-03 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 37.52 E-value: 6.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 17 GMNEEKV-ILDDVSLEIREHDFITILGGNGAGKSTLFNTIAGTlpvSSGKiYILGEDVTNYSPEKRAKYlSRV--FQDPK 93
Cdd:PLN03140 887 GVTEDRLqLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGR---KTGG-YIEGDIRISGFPKKQETF-ARIsgYCEQN 961
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 94 MGTAPRMTVAENLLVAKFRgekrgLIPRHLAsyKEEFQTVLAKIGN--GLENHIDTAVEF-----LSGGQRQALSLLMAT 166
Cdd:PLN03140 962 DIHSPQVTVRESLIYSAFL-----RLPKEVS--KEEKMMFVDEVMElvELDNLKDAIVGLpgvtgLSTEQRKRLTIAVEL 1034
|
170 180
....*....|....*....|....*
gi 1080618511 167 LKRPELLLLDEHTAALDPKTSQALM 191
Cdd:PLN03140 1035 VANPSIIFMDEPTSGLDARAAAIVM 1059
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
35-214 |
9.32e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 35.81 E-value: 9.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 35 HDFITILGGNGAGKSTLFNTIAGTLPVSSGKIYIL-GEDVTNYSPEKRakylsrvfqdpkmgtaprmtvaenllvakfrg 113
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIdGEDILEEVLDQL-------------------------------- 49
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1080618511 114 ekrgliprhlasykeefqtvlakigngLENHIDTAVEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSQALMTL 193
Cdd:smart00382 50 ---------------------------LLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLL 102
|
170 180
....*....|....*....|....*.
gi 1080618511 194 TDEFV-----KQDALTALMITHHMED 214
Cdd:smart00382 103 EELRLllllkSEKNLTVILTTNDEKD 128
|
|
| |
