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Conserved domains on  [gi|1079485418|ref|YP_009305771|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Heteralocha acutirostris]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
1-172 3.26e-54

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 169.16  E-value: 3.26e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVGYGLGMFLIVMVGVSAAGPIGGMAEVG--TVDNAGLSSVRLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGvvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160
                         170
                  ....*....|....
gi 1079485418 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
1-172 3.26e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 169.16  E-value: 3.26e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVGYGLGMFLIVMVGVSAAGPIGGMAEVG--TVDNAGLSSVRLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGvvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160
                         170
                  ....*....|....
gi 1079485418 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 9.76e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 56.74  E-value: 9.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  17 LAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPEAWGDWKVVGYGLGMFL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1079485418  97 IVMVGVSAAGPIGGMAEVGTVDNAGLSSVRldfSGVAAFYSRGAGLFLIGGWGLLLALFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIE---AIGELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
1-172 3.26e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 169.16  E-value: 3.26e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVGYGLGMFLIVMVGVSAAGPIGGMAEVG--TVDNAGLSSVRLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGvvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160
                         170
                  ....*....|....
gi 1079485418 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
1-172 4.81e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 161.08  E-value: 4.81e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVGYGLGMFLIVMVGVSAAGPIGGMAEVGTVDNAG-LSSVRLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKeFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160
                         170
                  ....*....|...
gi 1079485418 160 LVRGLSRGAIRAV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
1-172 4.41e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 158.86  E-value: 4.41e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVGYGLGMFLIVMVGVSAAGPIGGMAEVGTVDNAGLSSVRLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVLEL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160
                         170
                  ....*....|..
gi 1079485418 161 VRGLSRGAIRAV 172
Cdd:MTH00065  161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
1-163 2.68e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 103.34  E-value: 2.68e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVgygLGMFLIVMV-------------GVSAAGPIGGMAEVGTVDNAGLSSVRLDFSGVAAFYSRGAGLFLIGG 147
Cdd:MTH00109   82 TWVSNKVV---LGALLLGLLmelllvlyvlkddEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTG 158
                         170
                  ....*....|....*.
gi 1079485418 148 WGLLLALFVVLELVRG 163
Cdd:MTH00109  159 WSLFIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
1-172 7.23e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 94.29  E-value: 7.23e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   1 MMNFVLFLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  81 AWGDWKVVGYGLGMFLIVMVGVSAAGPIGGMAEVGTVDNAGlssvRLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVLEL 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEAN----NLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156
                         170
                  ....*....|..
gi 1079485418 161 VRGLSRGAIRAV 172
Cdd:MTH00214  157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
2-171 7.58e-19

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 78.41  E-value: 7.58e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418   2 MNFVLFLGTLFvLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPea 81
Cdd:MTH00045    1 MVFYLFLILML-FGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP-- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  82 wgdwkVVGYGLGMFLIVMVGVSAAGPIGGMAEVGTVDNAGLSSVrLDFSGVAAFYSRGAGLFLIGGWGLLLALFVVLELV 161
Cdd:MTH00045   78 -----SVSNLGEVLVLSLLLSLWVFISFDNFLELSNNNWSLVSL-SDLVGSSELYNSGGLYLLLGGFILLVALVVALVIS 151
                         170
                  ....*....|
gi 1079485418 162 RGLSRGAIRA 171
Cdd:MTH00045  152 FGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 9.76e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 56.74  E-value: 9.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1079485418  17 LAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPEAWGDWKVVGYGLGMFL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1079485418  97 IVMVGVSAAGPIGGMAEVGTVDNAGLSSVRldfSGVAAFYSRGAGLFLIGGWGLLLALFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIE---AIGELLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
7-73 1.13e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 40.87  E-value: 1.13e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1079485418   7 FLGTLFVLGGLAVASNPSPYYGVVGLVVASVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSL 73
Cdd:MTH00021    1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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