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Conserved domains on  [gi|1078672744|gb|AOW19850|]
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phosphate acetyltransferase [Urechidicola croceus]

Protein Classification

phosphate acetyltransferase( domain architecture ID 11481340)

phosphate acetyltransferase catalyzes the reversible interconversion of acetyl-CoA and acetyl phosphate and is involved in acetate metabolism

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK05632 PRK05632
phosphate acetyltransferase; Reviewed
1-693 0e+00

phosphate acetyltransferase; Reviewed


:

Pssm-ID: 235537 [Multi-domain]  Cd Length: 684  Bit Score: 1013.54  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744   1 MNKGIYIATSEPQSGKSIVAIGLMRMLLGRTPKVGYFRPIINDipegksdnhintiishfdlqlshdeafAFMRSDYVKK 80
Cdd:PRK05632    1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP---------------------------PLTMSEVEAL 53
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  81 INQGKESELIDTIIDKYKKLEDAFDFVLVEGTDFLGEgAAIELETNVNIAKNLAIPAIIVSSGSGKTMDKFIGDLQIAYD 160
Cdd:PRK05632   54 LASGQLDELLEEIVARYHALAKDCDVVLVEGLDPTRK-HPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAAS 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 161 SFR-DKDVEVLSIFANKVK---------KKNIDWVKKDITAYIETDVQ---------INVIPLIESLNNPTIKEIAKELD 221
Cdd:PRK05632  133 SFGgAKNANILGVIINKLNapvdeqgrtRPDLSEIFDDSSKANVDPSKlfassplplLGVVPWSPDLIAPRVIDIAKHLG 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 222 AKTLFGKEHINNQTSSFKVGAMQLRNHLTHLDENCLIITPGDRADIILGALQANISSnyPKISGIVLTGGLKPEKPILRL 301
Cdd:PRK05632  213 ATVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNG--PPIAGLLLTGGYEPDPRIAKL 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 302 IDGLSNI-VPIISSKLGTFEVANQIGAVKSHIYADNQQKILTSIETFENNVDVDDLAKRLIT--FRTEGMTPRMFQYNLI 378
Cdd:PRK05632  291 CEGAFETgLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDELLERLTAtsERSRRLSPPAFRYQLT 370
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 379 QKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNI-DNATIINPEKshLYNDFVDTFYNL 457
Cdd:PRK05632  371 ERARAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLpAGIEIIDPSE--VRERYVAPLVEL 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 458 RKHKNVTIDIAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDC 537
Cdd:PRK05632  449 RKHKGMTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDC 528
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 538 AINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSV 617
Cdd:PRK05632  529 AVNPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSV 608
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1078672744 618 AKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQAQ 693
Cdd:PRK05632  609 ARSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
 
Name Accession Description Interval E-value
PRK05632 PRK05632
phosphate acetyltransferase; Reviewed
1-693 0e+00

phosphate acetyltransferase; Reviewed


Pssm-ID: 235537 [Multi-domain]  Cd Length: 684  Bit Score: 1013.54  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744   1 MNKGIYIATSEPQSGKSIVAIGLMRMLLGRTPKVGYFRPIINDipegksdnhintiishfdlqlshdeafAFMRSDYVKK 80
Cdd:PRK05632    1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP---------------------------PLTMSEVEAL 53
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  81 INQGKESELIDTIIDKYKKLEDAFDFVLVEGTDFLGEgAAIELETNVNIAKNLAIPAIIVSSGSGKTMDKFIGDLQIAYD 160
Cdd:PRK05632   54 LASGQLDELLEEIVARYHALAKDCDVVLVEGLDPTRK-HPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAAS 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 161 SFR-DKDVEVLSIFANKVK---------KKNIDWVKKDITAYIETDVQ---------INVIPLIESLNNPTIKEIAKELD 221
Cdd:PRK05632  133 SFGgAKNANILGVIINKLNapvdeqgrtRPDLSEIFDDSSKANVDPSKlfassplplLGVVPWSPDLIAPRVIDIAKHLG 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 222 AKTLFGKEHINNQTSSFKVGAMQLRNHLTHLDENCLIITPGDRADIILGALQANISSnyPKISGIVLTGGLKPEKPILRL 301
Cdd:PRK05632  213 ATVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNG--PPIAGLLLTGGYEPDPRIAKL 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 302 IDGLSNI-VPIISSKLGTFEVANQIGAVKSHIYADNQQKILTSIETFENNVDVDDLAKRLIT--FRTEGMTPRMFQYNLI 378
Cdd:PRK05632  291 CEGAFETgLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDELLERLTAtsERSRRLSPPAFRYQLT 370
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 379 QKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNI-DNATIINPEKshLYNDFVDTFYNL 457
Cdd:PRK05632  371 ERARAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLpAGIEIIDPSE--VRERYVAPLVEL 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 458 RKHKNVTIDIAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDC 537
Cdd:PRK05632  449 RKHKGMTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDC 528
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 538 AINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSV 617
Cdd:PRK05632  529 AVNPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSV 608
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1078672744 618 AKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQAQ 693
Cdd:PRK05632  609 ARSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
PtaN COG0857
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
1-693 0e+00

BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];


Pssm-ID: 440618 [Multi-domain]  Cd Length: 697  Bit Score: 754.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744   1 MNKGIYIATSEPQSGKSIVAIGLMRMLLGRTPKVGYFRPIINDIPEGKS-DNHINTIISHFDLQLSHDEAFAFMRSDYVK 79
Cdd:COG0857     1 MMKSIYIASTEPGSGKTSVALGLARALQRKGLRVGYFKPIGQSLVGGGErDEDVELIREHLGLDLPYEDASPVTLDEVET 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  80 KINQGKESELIDTIIDKYKKLEDAFDFVLVEGTDFLGEGAAIELETNVNIAKNLAIPAIIVSSGSGKTMDKFIGDLQIAY 159
Cdd:COG0857    81 LLAEGDPDELLERIVERYEALAAECDVVLVEGSDPTGVGSPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLLAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 160 DSFRDKDVEVLSIFANKVKKKNIDWVKKDITAYIE-TDVQ-INVIPLIESLNNPTIKEIAKELDAKTLFGKEHINNQTSS 237
Cdd:COG0857   161 DEFRGEGARVLGVIINRVPPEKLEEVREALRPFLEgSGIPvLGVIPENPELAAPTVRDLAEALGAEVLNGGELLDRRVES 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 238 FKVGAMQLRNHLTHLDENCLIITPGDRADIILGALQANISSNyPKISGIVLTGGLKPEKPILRLIDGLSNIVPIISSKLG 317
Cdd:COG0857   241 VVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGT-PSIAGLILTGGLPPDPAVLRLAEGLGQTLPILSVELD 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 318 TFEVANQIGAVKSHIYADNQQKILTSIETFENNVDVDDLAKRLITFRTeGMTPRMFQYNLIQKAKKIRKHIVLPEGNEPR 397
Cdd:COG0857   320 TYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSRLGLPRS-RLSPPAFFYYLLERAARAAKRIVLPEGGEDR 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 398 ILQAVHNLQVMDIV-DVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVDTFYNLRKHKNVTIDIAKDIMKDHS 476
Cdd:COG0857   399 RILAAAICLLRRIAaCVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAAEVYLRRRKKKGVTVAAAQLEDDVVL 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 477 YFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDCAINPNPNAAQLAEIAISSA 556
Cdd:COG0857   479 YTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVVVGDCACAPNPPPEELALAAIISSSS 558
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 557 ESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIF 636
Cdd:COG0857   559 AAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAAAADVVVAKAKPSPVAGAAAAFVFPF 638
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1078672744 637 PDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQAQ 693
Cdd:COG0857   639 LDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQQQ 695
PTA_PTB pfam01515
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ...
373-689 2.68e-155

Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.


Pssm-ID: 396207 [Multi-domain]  Cd Length: 318  Bit Score: 451.77  E-value: 2.68e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 373 FQYNLIQKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVD 452
Cdd:pfam01515   1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDLDGIEIVDPETSPRLEEYAD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 453 TFYNLRKHKNVTIDIAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVS 532
Cdd:pfam01515  81 FYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 533 VFGDCAINPNPNAAQLAEIAISSAESSLAFG-IEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDA 611
Cdd:pfam01515 161 FFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFDA 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1078672744 612 AVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTA 689
Cdd:pfam01515 241 ALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAITA 318
pta TIGR00651
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ...
388-689 1.11e-147

phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]


Pssm-ID: 273196 [Multi-domain]  Cd Length: 303  Bit Score: 431.48  E-value: 1.11e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 388 IVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVDTFYNLRKHKNVTIDI 467
Cdd:TIGR00651   1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKAAGCNLDLGHVVIIDPDVSPDRESYAERYVELRKHKGMTEAQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 468 AKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDCAINPNPNAAQ 547
Cdd:TIGR00651  81 ARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNAEQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 548 LAEIAISSAESSLAFG-IEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSVAKTKLPNSE 626
Cdd:TIGR00651 161 LAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPNSP 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1078672744 627 VAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTA 689
Cdd:TIGR00651 241 VAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAITA 303
DTBS cd03109
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ...
15-177 4.25e-11

dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.


Pssm-ID: 349763 [Multi-domain]  Cd Length: 189  Bit Score: 62.59  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  15 GKSIVAIGLMRMLLGRTPKVGYFRPIINDIPEGK-SDNHINTIISHFDLQLSHDEAFAFMR--SDYVKKINQGKeSELID 91
Cdd:cd03109    13 GKTVVSAGLARALRKKGIKVGYLKPVQTGCPGLEdSDAELLRKLAGLLLDLELINPYRFEAplSPHLAAELEGR-DIDLE 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  92 TIIDKYKKLEDAFDFVLVEGTDFLGEGaAIELETNVNIAKNLAIPAIIVSSGSGKTmdkfIGDLQIAYDSFRDKDVEVLS 171
Cdd:cd03109    92 EIVRALEELAKSYDVVLVEGAGGLLVP-LTEGYLNADLARALGLPVILVARGGLGT----INHTLLTLEALKSRGLDVAG 166

                  ....*.
gi 1078672744 172 IFANKV 177
Cdd:cd03109   167 VVLNGI 172
 
Name Accession Description Interval E-value
PRK05632 PRK05632
phosphate acetyltransferase; Reviewed
1-693 0e+00

phosphate acetyltransferase; Reviewed


Pssm-ID: 235537 [Multi-domain]  Cd Length: 684  Bit Score: 1013.54  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744   1 MNKGIYIATSEPQSGKSIVAIGLMRMLLGRTPKVGYFRPIINDipegksdnhintiishfdlqlshdeafAFMRSDYVKK 80
Cdd:PRK05632    1 MSRSIYLAPTGTGVGLTSVSLGLMRALERKGVKVGFFKPIAQP---------------------------PLTMSEVEAL 53
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  81 INQGKESELIDTIIDKYKKLEDAFDFVLVEGTDFLGEgAAIELETNVNIAKNLAIPAIIVSSGSGKTMDKFIGDLQIAYD 160
Cdd:PRK05632   54 LASGQLDELLEEIVARYHALAKDCDVVLVEGLDPTRK-HPFEFSLNAEIAKNLGAEVVLVSSGGNDTPEELAERIELAAS 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 161 SFR-DKDVEVLSIFANKVK---------KKNIDWVKKDITAYIETDVQ---------INVIPLIESLNNPTIKEIAKELD 221
Cdd:PRK05632  133 SFGgAKNANILGVIINKLNapvdeqgrtRPDLSEIFDDSSKANVDPSKlfassplplLGVVPWSPDLIAPRVIDIAKHLG 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 222 AKTLFGKEHINNQTSSFKVGAMQLRNHLTHLDENCLIITPGDRADIILGALQANISSnyPKISGIVLTGGLKPEKPILRL 301
Cdd:PRK05632  213 ATVLNEGDILTRRVKSVTVCARSIPNMLEHLKPGSLVVTPGDRSDVILAALLAAMNG--PPIAGLLLTGGYEPDPRIAKL 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 302 IDGLSNI-VPIISSKLGTFEVANQIGAVKSHIYADNQQKILTSIETFENNVDVDDLAKRLIT--FRTEGMTPRMFQYNLI 378
Cdd:PRK05632  291 CEGAFETgLPVLSVDTNTYQTALRLQSFNGEVPVDDHERIETVLELVASHVDTDELLERLTAtsERSRRLSPPAFRYQLT 370
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 379 QKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNI-DNATIINPEKshLYNDFVDTFYNL 457
Cdd:PRK05632  371 ERARAAKKRIVLPEGDEPRTLKAAAICLERGIADCVLLGNPEEIRRVAAAQGVDLpAGIEIIDPSE--VRERYVAPLVEL 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 458 RKHKNVTIDIAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDC 537
Cdd:PRK05632  449 RKHKGMTEEVAREQLEDNVYFGTMMLALGEVDGLVSGAVHTTANTIRPALQLIKTAPGSSLVSSVFFMLLPDQVLVYGDC 528
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 538 AINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSV 617
Cdd:PRK05632  529 AVNPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGSGADVEKVREATRLARERRPDLLIDGPLQYDAAVDPSV 608
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1078672744 618 AKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQAQ 693
Cdd:PRK05632  609 ARSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSAGAVSIGPMLQGLRKPVNDLSRGALVDDIVNTIAITAIQAQ 684
PtaN COG0857
BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];
1-693 0e+00

BioD-like N-terminal domain of phosphotransacetylase [General function prediction only];


Pssm-ID: 440618 [Multi-domain]  Cd Length: 697  Bit Score: 754.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744   1 MNKGIYIATSEPQSGKSIVAIGLMRMLLGRTPKVGYFRPIINDIPEGKS-DNHINTIISHFDLQLSHDEAFAFMRSDYVK 79
Cdd:COG0857     1 MMKSIYIASTEPGSGKTSVALGLARALQRKGLRVGYFKPIGQSLVGGGErDEDVELIREHLGLDLPYEDASPVTLDEVET 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  80 KINQGKESELIDTIIDKYKKLEDAFDFVLVEGTDFLGEGAAIELETNVNIAKNLAIPAIIVSSGSGKTMDKFIGDLQIAY 159
Cdd:COG0857    81 LLAEGDPDELLERIVERYEALAAECDVVLVEGSDPTGVGSPFELSLNARIAKNLGAPVLLVASGGGRTPEELVDALLLAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 160 DSFRDKDVEVLSIFANKVKKKNIDWVKKDITAYIE-TDVQ-INVIPLIESLNNPTIKEIAKELDAKTLFGKEHINNQTSS 237
Cdd:COG0857   161 DEFRGEGARVLGVIINRVPPEKLEEVREALRPFLEgSGIPvLGVIPENPELAAPTVRDLAEALGAEVLNGGELLDRRVES 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 238 FKVGAMQLRNHLTHLDENCLIITPGDRADIILGALQANISSNyPKISGIVLTGGLKPEKPILRLIDGLSNIVPIISSKLG 317
Cdd:COG0857   241 VVVGAMSVPNALERLREGALVITPGDRSDILLAALLAALSGT-PSIAGLILTGGLPPDPAVLRLAEGLGQTLPILSVELD 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 318 TFEVANQIGAVKSHIYADNQQKILTSIETFENNVDVDDLAKRLITFRTeGMTPRMFQYNLIQKAKKIRKHIVLPEGNEPR 397
Cdd:COG0857   320 TYTTAERLERVRGRIRADDPRKIELALELFAEHVDVDWLLSRLGLPRS-RLSPPAFFYYLLERAARAAKRIVLPEGGEDR 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 398 ILQAVHNLQVMDIV-DVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVDTFYNLRKHKNVTIDIAKDIMKDHS 476
Cdd:COG0857   399 RILAAAICLLRRIAaCVLLGGPEEIIRVAAAQGGLLLDGIEIIDPPDSRLRYVAAEVYLRRRKKKGVTVAAAQLEDDVVL 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 477 YFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDCAINPNPNAAQLAEIAISSA 556
Cdd:COG0857   479 YTGMMMVHEGDGLGMGSGATTTTTTTIPPQLIITKTGPGVVSSSSFFLMLLQVVVVGDCACAPNPPPEELALAAIISSSS 558
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 557 ESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIF 636
Cdd:COG0857   559 AAAAGFGPEPAMISLSSSTSGSGGGVDVVKVATATALVRRRDLLLDGPGPYQAAAAADVVVAKAKPSPVAGAAAAFVFPF 638
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1078672744 637 PDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQAQ 693
Cdd:COG0857   639 LDTNNTNNTAKARQASAGAVAPGPQGLGLPVNDLDLSRGVVDIDITIALTIIAAQQQ 695
Pta COG0280
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production ...
372-691 4.69e-168

Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production and conversion];


Pssm-ID: 440049 [Multi-domain]  Cd Length: 320  Bit Score: 484.19  E-value: 4.69e-168
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 372 MFQYNLIQKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFV 451
Cdd:COG0280     1 KFFRPLIERAKAAPKRIVFAEGEDERVLRAAQEALDEGLAEPILVGRPEKIEARAEELGLDLSGFEIIDPEDSPRYEEYA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 452 DTFYNLRKHKNVTIDIAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRV 531
Cdd:COG0280    81 EAYYELRKRKGVTPEEARELVRDAAYFAAMMVRLGEADGLVKGAVGTTADLLRPVLQIIGLRPGVKRVSHVFLMELPDRL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 532 SVFGDCAINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDA 611
Cdd:COG0280   161 LFITDTAVNIDPTAEQLADIAINAADTARAFGIEPKVALLSASEFGSPKGPSTDKVREATKMARGQIPDLEVDGELQFDA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 612 AVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQ 691
Cdd:COG0280   241 ALSPEAAKRKGPDSPVAGDANVLVFPDLEAGNILYKLLQRLAGAEAIGPILLGLAKPVHLLSRGDSVRDIVNSIALAAVQ 320
eutD PRK09653
phosphotransacetylase;
376-695 7.83e-166

phosphotransacetylase;


Pssm-ID: 236609 [Multi-domain]  Cd Length: 324  Bit Score: 478.57  E-value: 7.83e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 376 NLIQKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVDTFY 455
Cdd:PRK09653    6 SLKEKAKGKKKKIVLPEGEDERVLKAAKRLQKEGLVEPILLGNPEEIRAKAKELGLDLDGVEIIDPETYPLLEEFAEAFV 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 456 NLRKHKNVTIDiAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFG 535
Cdd:PRK09653   86 ELRKGKGTEED-AAELLKDPNYFGTMLVKLGKADGMVSGAIHSTADTLRPALQIIKTKPGVKTVSSVFIMVKGDERYIFA 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 536 DCAINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDM 615
Cdd:PRK09653  165 DCAVNPNPTAEQLAEIAINSAETAKAFGIDPKVAMLSFSTKGSAKGPEVDKVQEATEIAKELAPDLKIDGELQFDAAFVP 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 616 SVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQAQDQ 695
Cdd:PRK09653  245 EVAAKKAPGSPVAGKANVFVFPSLEAGNIGYKIAQRLGGFEAVGPILQGLNKPVNDLSRGCSVEDIYNLALITAAQAQGE 324
PTA_PTB pfam01515
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ...
373-689 2.68e-155

Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.


Pssm-ID: 396207 [Multi-domain]  Cd Length: 318  Bit Score: 451.77  E-value: 2.68e-155
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 373 FQYNLIQKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVD 452
Cdd:pfam01515   1 FLERIFERAKKAKKRIVFPEGEDERVLKAAQKLLQQGIADPILIGDEIEIKAKALGLDLDLDGIEIVDPETSPRLEEYAD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 453 TFYNLRKHKNVTIDIAKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVS 532
Cdd:pfam01515  81 FYYELRKRKGMTPEIAREIVRDPNYFAAMLVKLGEADGMVSGAVNTTADTLRPALQIIGTKPGVKTVSSVFIMLLPDGLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 533 VFGDCAINPNPNAAQLAEIAISSAESSLAFG-IEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDA 611
Cdd:pfam01515 161 FFADCAVNPNPTAEELAEIALMSAKTAKRFGiIEPRVALLSYSTFGSGKGEDVEKVREATKIVRERAPDLVVDGELQFDA 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1078672744 612 AVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTA 689
Cdd:pfam01515 241 ALVEEVAAQKAPDSPVAGKANVFVFPDLEAGNIGYKIAQRLGGAEAIGPILQGLAKPVNDLSRGASVEDIVNTAAITA 318
pta TIGR00651
phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from ...
388-689 1.11e-147

phosphate acetyltransferase; Alternate name: phosphotransacetylase Model contains a gene from E.coli coding for ethanolamine utilization protein (euti) and also contains similarity to malate oxidoreductases [Central intermediary metabolism, Other, Energy metabolism, Fermentation]


Pssm-ID: 273196 [Multi-domain]  Cd Length: 303  Bit Score: 431.48  E-value: 1.11e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 388 IVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINPEKSHLYNDFVDTFYNLRKHKNVTIDI 467
Cdd:TIGR00651   1 IVFPEGWEPRVLKAAALLAERGIATPVVLGNPEEIQPKAAGCNLDLGHVVIIDPDVSPDRESYAERYVELRKHKGMTEAQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 468 AKDIMKDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVSVFGDCAINPNPNAAQ 547
Cdd:TIGR00651  81 ARKQLRDESYFATMMVALGEADGLVSGAVHTTADTLRPALQIIKTLPGVKIVSSVFIMDLGEEVLVFADCAVNPDPNAEQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 548 LAEIAISSAESSLAFG-IEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAAVDMSVAKTKLPNSE 626
Cdd:TIGR00651 161 LAEIAIQSANSAKSFGeIEPKVALLSYSTKGSGKGEEVEKVREATRIAKEKRPDLTIDGELQFDAAFVEKVAEKKAPNSP 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1078672744 627 VAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTA 689
Cdd:TIGR00651 241 VAGSANVFVFPDLDAGNIGYKIVQRLGDAEAIGPILQGLNKPVNDLSRGCSVEDIVNTGAITA 303
PRK07232 PRK07232
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
377-693 1.06e-90

bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed


Pssm-ID: 235976 [Multi-domain]  Cd Length: 752  Bit Score: 298.55  E-value: 1.06e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 377 LIQKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNID---NATIINPEKSHLYNDFVDT 453
Cdd:PRK07232  431 IFAKAKKDPKRVVFAEGEEERVLRAAQEVVDEGLAKPILIGRPEVIEARIKKLGLDLKagvDFEIVNPEDDPRYEEYWQY 510
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 454 FYNLRKHKNVTIDIAKDIM-KDHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVS 532
Cdd:PRK07232  511 YYELLQRKGVTPEDARRLVrRDRTVIGAMMVARGDADAMICGLTGRYHEHLRPVRQVIGLRPGVHTAAAMNALLLKGGNL 590
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 533 VFGDCAINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAA 612
Cdd:PRK07232  591 FIADTYVNEDPTAEELAEIALMAAEEVRRFGIEPRVALLSHSNFGSSDSPSARKMREAVELLRERAPDLEVDGEMHGDAA 670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 613 VDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQA 692
Cdd:PRK07232  671 LNEEIRKDLYPFSRLKGPANVLVMPNLEAANISYNLLKELGGGVTIGPILLGMAKPVHILTPSATVRRIVNMTALAVVDA 750

                  .
gi 1078672744 693 Q 693
Cdd:PRK07232  751 Q 751
PRK12862 PRK12862
malic enzyme; Reviewed
377-693 6.24e-79

malic enzyme; Reviewed


Pssm-ID: 183799 [Multi-domain]  Cd Length: 763  Bit Score: 267.53  E-value: 6.24e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 377 LIQKAKKIRKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNA---TIINPEKSHLYNDFVDT 453
Cdd:PRK12862  439 VFAAAKAAPKRVVFAEGEDERVLRAAQVVVDEGLAKPILIGRPAVIEARIERAGLRLRPGvdfEIVNPEDDPRYRDYWDT 518
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 454 FYNLRKHKNVTIDIAKDIMK-DHSYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVFFMCLEDRVS 532
Cdd:PRK12862  519 YHALMGRKGVTPEMARREVRrRTTLIGAMMVKRGEADAMICGTEGRYERHLEFVLQVIGKRPGVRVYAAMSLLILPGRTL 598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 533 VFGDCAINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKIEGPIQYDAA 612
Cdd:PRK12862  599 FLADTHVNEDPTAEELAEITILAAEEVRRFGIEPKVALLSHSNFGSSDSPSARKMREALEILRERAPDLEVDGEMHGDAA 678
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 613 VDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETG-ALAIGPMLQGLNKPVNDLSRGCTVDDIFNTIILTAIQ 691
Cdd:PRK12862  679 LDEELRDRIFPDSRLEGEANLLVFPNLDAANIAYNLLKTAAGnGLAVGPILLGAAKPVHILTPSATVRRIVNMTALAVAD 758

                  ..
gi 1078672744 692 AQ 693
Cdd:PRK12862  759 AN 760
PRK12861 PRK12861
malic enzyme; Reviewed
373-692 3.11e-52

malic enzyme; Reviewed


Pssm-ID: 183798 [Multi-domain]  Cd Length: 764  Bit Score: 193.18  E-value: 3.11e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 373 FQYNLIQKAKKI-----RKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNI---DNATIINPEKS 444
Cdd:PRK12861  431 FMKPLFAAARQLvrdggKARIVFTEGEDERVLRAVQVIVDEKLARPILVGRPEVLLARIERFGLRLrlgQDVEVTNPEYD 510
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 445 HLYNDFVDTFYNLRKHKNVTIDIAKDIMKDH-SYFGTMMVYKGLVDGMVSGSVNTTQHTIRPALQFIKTKPNVSVVSSVF 523
Cdd:PRK12861  511 ERFPQYWTTYWELRCRDGISKEMARVEMRRRlTLIGAMMVRLGDADGMICGTVGEYHNHLRFVDEVIGRKPGASTYAAMN 590
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 524 FMCLEDRVSVFGDCAINPNPNAAQLAEIAISSAESSLAFGIEPKIAMLSYSSGTSGKGVDVDKVREATEIVKKKRPDLKI 603
Cdd:PRK12861  591 ILLLDQRTVALVDTHVNDNPDAEQIAEFTIAAARQMEWLNLTPKVALLSRSNFGSGSAASGVKMRRALEIVREQAPDLEA 670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 604 EGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGA-LAIGPMLQGLNKPVNDLSRGCTVDDIF 682
Cdd:PRK12861  671 DGEMHGDCALDEGLRARLLPMSPLKGAANLLVCPNVDAGNIAYNLLKTEAGSnVAVGPFLLGVNAPVNILTSSATVRRIV 750
                         330
                  ....*....|
gi 1078672744 683 NTIILTAIQA 692
Cdd:PRK12861  751 NMAALTVIEA 760
DRTGG pfam07085
DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated ...
215-325 8.34e-30

DRTGG domain; This presumed domain is about 120 amino acids in length. It is found associated with CBS domains pfam00571, as well as the CbiA domain pfam01656. The function of this domain is unknown. It is named the DRTGG domain after some of the most conserved residues. This domain may be very distantly related to a pair of CBS domains. There are no significant sequence similarities, but its length and association with CBS domains supports this idea (Bateman A, pers. obs.).


Pssm-ID: 429285 [Multi-domain]  Cd Length: 105  Bit Score: 113.36  E-value: 8.34e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 215 EIAKELDAKTLFGKEHINNQTSSFKVGAMQLRNHLTHLDENCLIITPGDRADIILGALQANissnypkISGIVLTGGLKP 294
Cdd:pfam07085   1 DIARILGAEVLNGGDGLLRRVGKVVVGAMSVENMLKYLRPGDLVITPGDREDIQLAALEAG-------IAGLILTGGFEP 73
                          90       100       110
                  ....*....|....*....|....*....|.
gi 1078672744 295 EKPILRLIDGLSniVPIISSKLGTFEVANQI 325
Cdd:pfam07085  74 SPEVLKLAEELG--LPVLSTPYDTFTTASRI 102
AAA_26 pfam13500
AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis ...
3-212 4.88e-26

AAA domain; This domain is found in a number of proteins involved in cofactor biosynthesis such as dethiobiotin synthase and cobyric acid synthase. This domain contains a P-loop motif.


Pssm-ID: 433259 [Multi-domain]  Cd Length: 198  Bit Score: 105.80  E-value: 4.88e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744   3 KGIYIATSEPQSGKSIVAIGLMRMLLGRTPKVGYFRPIINDIPEGKSDNHINTIISHfDLQLSHDEAFAFMRSdYVKKI- 81
Cdd:pfam13500   1 RTLFVTGTDTGVGKTVVSLGLARALKRRGVKVGYWKPVQTGLVEDGDSELVKRLLGL-DQSYEDPEPFRLSAP-LSPHLa 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  82 -NQGKESELIDTIIdkyKKLEDAFDFVLVEGTDFLGEGAAIELeTNVNIAKNLAIPAIIVSSGSGKTmdkfIGDLQIAYD 160
Cdd:pfam13500  79 aRQEGVTIDLEKII---YELPADADPVVVEGAGGLLVPINEDL-LNADIAANLGLPVILVARGGLGT----INHTLLTLE 150
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1078672744 161 SFRDKDVEVLSIFANKVK-KKNIDwvkkDITAYIETDVqINVIPLIESLNNPT 212
Cdd:pfam13500 151 ALRQRGIPVLGVILNGVPnPENVR----TIFAFGGVPV-LGAVPYLPDLTAPT 198
PRK05805 PRK05805
phosphate butyryltransferase; Validated
377-695 1.91e-13

phosphate butyryltransferase; Validated


Pssm-ID: 180267  Cd Length: 301  Bit Score: 71.66  E-value: 1.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 377 LIQKAKKI-RKHIVLPEGNEPRILQAVHNLQVMDIVDVTLLGDKKIINAIVKEFDLNIDNATIINpEKshlyndfvdtfy 455
Cdd:PRK05805    8 ILSKAKEQpPKTISVAVAQDEPVLEAVKEAKELGIANAILVGDKEKIKEIAKEIDMDLEDFEIID-EK------------ 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 456 NLRKHKNVTIDIAKDIMKDhsyfgtmMVYKGLVDgmvsgsvntTQHTIRPALQF---IKTKPNVSVVSsVFFMCLEDRVS 532
Cdd:PRK05805   75 DNRKAALKAVELVSSGKAD-------MVMKGLVD---------TANFLRAVLNKeigLRTGKTMSHVA-VFEVPKYDRLL 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 533 VFGDCAINPNPNAAQLAEIAISSAESSLAFGIE-PKIAMLSyssgtsgkgvdvdkvreATEIVKKKRPD----------- 600
Cdd:PRK05805  138 FLTDAAFNIAPDLKEKIDIINNAVTVAHAIGIEnPKVAPIC-----------------AVEVVNPKMPAtldaallskms 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 601 ----LK---IEGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGAlAIGPMLQGLNKPVNDLS 673
Cdd:PRK05805  201 drgqIKgciVDGPLALDNALSEEAAKHKGIDGPVAGNADILLVPNIEAGNVMYKTLTYFADC-KNGGLLVGTSAPVVLTS 279
                         330       340
                  ....*....|....*....|..
gi 1078672744 674 RGCTVDDIFNTIILTAIQAQDQ 695
Cdd:PRK05805  280 RADSHETKLNSIALAALVAAKL 301
DTBS cd03109
dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the ...
15-177 4.25e-11

dethiobiotin synthetase; Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and carbon dioxide. The enzyme utilizes carbon dioxide instead of hydrogen carbonate as substrate and is dependent on ATP and divalent metal ions as cofactors.


Pssm-ID: 349763 [Multi-domain]  Cd Length: 189  Bit Score: 62.59  E-value: 4.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  15 GKSIVAIGLMRMLLGRTPKVGYFRPIINDIPEGK-SDNHINTIISHFDLQLSHDEAFAFMR--SDYVKKINQGKeSELID 91
Cdd:cd03109    13 GKTVVSAGLARALRKKGIKVGYLKPVQTGCPGLEdSDAELLRKLAGLLLDLELINPYRFEAplSPHLAAELEGR-DIDLE 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  92 TIIDKYKKLEDAFDFVLVEGTDFLGEGaAIELETNVNIAKNLAIPAIIVSSGSGKTmdkfIGDLQIAYDSFRDKDVEVLS 171
Cdd:cd03109    92 EIVRALEELAKSYDVVLVEGAGGLLVP-LTEGYLNADLARALGLPVILVARGGLGT----INHTLLTLEALKSRGLDVAG 166

                  ....*.
gi 1078672744 172 IFANKV 177
Cdd:cd03109   167 VVLNGI 172
PRK07742 PRK07742
phosphate butyryltransferase; Validated
529-674 1.43e-10

phosphate butyryltransferase; Validated


Pssm-ID: 236086  Cd Length: 299  Bit Score: 62.80  E-value: 1.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 529 DRVSVFGDCAINPNPNAAQLAEIAISSAESSLAFGIE-PKIAMLSyssgtsgkGVD-VDKVREATE-----IVKKKRPDL 601
Cdd:PRK07742  133 DRLIFVTDAAMNIAPDLEQKAAIIQNAVEVARAIGIDlPKVAPLA--------AVEvVNPAMQATIdaaalTQMNRRGQI 204
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1078672744 602 K---IEGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGAlAIGPMLQGLNKPVNDLSR 674
Cdd:PRK07742  205 KncvVDGPLALDNAVSQIAAEHKGIVSDVAGKADILLVPTIEAGNVLYKSLVYFADA-KVGAMIAGAKAPIVLTSR 279
PRK08190 PRK08190
bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated
536-659 1.63e-10

bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated


Pssm-ID: 236180 [Multi-domain]  Cd Length: 466  Bit Score: 63.75  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 536 DCAINPNPNAAQLAEI---AISSAessLAFGIE-PKIAMLSyssgtsgkgvdvdkvreATEIVKKKRPDL---------- 601
Cdd:PRK08190  300 DAAINIAPTLEDKRDIvqnAIDLA---HALGVEePKVAILS-----------------AVETVNPKMPSTldaaalckma 359
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1078672744 602 --------KIEGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIFPDLNTGNNTYKAVQRETGALAIG 659
Cdd:PRK08190  360 drgqitggIVDGPLAFDNAISAEAARTKGIVSPVAGQADILVVPDLEAGNMLAKQLTYLAGADAAG 425
PRK14869 PRK14869
putative manganese-dependent inorganic diphosphatase;
187-412 8.23e-10

putative manganese-dependent inorganic diphosphatase;


Pssm-ID: 237843 [Multi-domain]  Cd Length: 546  Bit Score: 61.77  E-value: 8.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 187 KDIT-AYIETDVqinviPLIESLNNPTIKEIAKELDAKTLFGKEHINNQTSSFKVGAMQLRNHLTHLDENCLIITpGDRA 265
Cdd:PRK14869  118 SDLArAYMDILD-----PEILSKSPTSLENIIRTLDGEVLVGAEEDKVEEGKVVVAAMAPESLLERIEEGDIVIV-GDRE 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 266 DIILGALQAnissnypKISGIVLTGGLKPEKPILRLIDglSNIVPIISSKLGTFEVANQIgavkshiyadNQQKILTSIE 345
Cdd:PRK14869  192 DIQLAAIEA-------GVRLLIITGGAPVSEDVLELAK--ENGVTVISTPYDTFTTARLI----------NQSIPVSYIM 252
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 346 TFEN--NVDVDDL---AKRLI---TFRT----------EGMTPRmfqYNLIQkakKIRKHIVLPEGNEPRilQAVHNL-- 405
Cdd:PRK14869  253 TTEDlvTFSKDDYledVKEVMlksRYRSypvvdedgkvVGVISR---YHLLS---PVRKKVILVDHNEKS--QAVEGIee 324

                  ....*...
gi 1078672744 406 -QVMDIVD 412
Cdd:PRK14869  325 aEILEIID 332
bioD TIGR00347
dethiobiotin synthase; Dethiobiotin synthase is involved in biotin biosynthesis and catalyses ...
15-175 3.40e-07

dethiobiotin synthase; Dethiobiotin synthase is involved in biotin biosynthesis and catalyses the reaction (CO2 + 7,8-diaminononanoate + ATP = dethiobiotin + phosphate + ADP). The enzyme binds ATP (see motif in first 12 residues of the SEED alignment) and requires magnesium as a co-factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 129447 [Multi-domain]  Cd Length: 166  Bit Score: 50.44  E-value: 3.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  15 GKSIVAIGLMRMLLGRTPKVGYFRPIINDIPEGKSDNhiNTIISHFDLQLSHDE----AFAFMRSDYVKKINQGKESELi 90
Cdd:TIGR00347  10 GKTVASSALAAKLKKAGYSVGYYKPVQTGIEKTNSDA--LLLQNISGTALDWDEvnpyAFALPLSPHIAADQEGRPIDL- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744  91 DTIIDKYKKLEDAFDFVLVEGTDflGEGAAI-ELETNVNIAKNLAIPAIIVSSGSGKTMDKFIgdLQIAYdsFRDKDVEV 169
Cdd:TIGR00347  87 EELSKHLRTLEQKYDFVLVEGAG--GLCVPItEEYTTADLIKLLQLPVILVVRVKLGTINHTL--LTVEH--ARQTGLTL 160

                  ....*.
gi 1078672744 170 LSIFAN 175
Cdd:TIGR00347 161 AGVILN 166
PRK11890 PRK11890
phosphate acetyltransferase; Provisional
536-643 9.83e-07

phosphate acetyltransferase; Provisional


Pssm-ID: 183361  Cd Length: 312  Bit Score: 51.14  E-value: 9.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078672744 536 DCAINPNPNAAQLAEIAISSAESSLAFGI-EPKIAMLSyssgtsgkgvdvdkvreATEIVKKKRP--------------- 599
Cdd:PRK11890  146 DAAVNIAPTLEDKADIVQNAIDLAHALGFdEPRVAILS-----------------AVETVNPKIPstldaaalckmadrg 208
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1078672744 600 ---DLKIEGPIQYDAAVDMSVAKTKLPNSEVAGQASVLIFPDLNTGN 643
Cdd:PRK11890  209 qitGAILDGPLAFDNAISPEAARIKGIVSPVAGDADILVVPDLEAGN 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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