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Conserved domains on  [gi|1078663924|gb|AOW11033|]
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hypothetical protein EM308_16920 [Flavobacterium gilvum]

Protein Classification

lysozyme inhibitor LprI family protein( domain architecture ID 10007952)

lysozyme inhibitor LprI family protein similar to Mycobacterium tuberculosis lipoprotein LprI, which acts as a lysozyme Inhibitor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YecT COG3755
Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];
1-90 8.65e-30

Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];


:

Pssm-ID: 442969  Cd Length: 121  Bit Score: 102.46  E-value: 8.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078663924   1 MEMNETAAASFIKADTELNKVYKQLMTMLNQSE-KTLLIQAEKDWVKFRDSHCKFEASQYEGGSIKPLIYSTCLEQLTRK 79
Cdd:COG3755    31 AEMNACAAKEYQKADKELNKAYKALMKRLSAPEaKAALRKAQRAWIKYRDAECAFAAAAYEGGSIAPLAYASCLARLTQE 110

                          90
                  ....*....|.
gi 1078663924  80 RIAEIKASIKE 90
Cdd:COG3755   111 RTKELESLLEC 121
 
Name Accession Description Interval E-value
YecT COG3755
Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];
1-90 8.65e-30

Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];


Pssm-ID: 442969  Cd Length: 121  Bit Score: 102.46  E-value: 8.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078663924   1 MEMNETAAASFIKADTELNKVYKQLMTMLNQSE-KTLLIQAEKDWVKFRDSHCKFEASQYEGGSIKPLIYSTCLEQLTRK 79
Cdd:COG3755    31 AEMNACAAKEYQKADKELNKAYKALMKRLSAPEaKAALRKAQRAWIKYRDAECAFAAAAYEGGSIAPLAYASCLARLTQE 110

                          90
                  ....*....|.
gi 1078663924  80 RIAEIKASIKE 90
Cdd:COG3755   111 RTKELESLLEC 121
LprI pfam07007
Lysozyme inhibitor LprI; This family consists of several bacterial proteins of around 120 ...
 1-83 2.41e-17

Lysozyme inhibitor LprI; This family consists of several bacterial proteins of around 120 residues in length. Members of this family contain four highly conserved cysteine residues. Family members include lipoprotein LprI from Mycobacterium, which binds to and inhibits macrophage lysozyme, which may aid bacterial survival.


Pssm-ID: 429244  Cd Length: 103  Bit Score: 70.11  E-value: 2.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078663924   1 MEMNETAAASFIKADTELNKVYKQLMTMLNQSEK--------TLLIQAEKDWVKFRDSHCKFEASQYEGGSIK-PLIYST 71
Cdd:pfam07007  12 AEMNACASAAYKAADAELNAAYKALLASADEREKaaldpearAALRAAQRAWIKYRDAECALVAALAGGGSGAgALAYAS 91

                          90
                  ....*....|..
gi 1078663924  72 CLEQLTRKRIAE 83
Cdd:pfam07007  92 CLAELTRERAAE 103
 
Name Accession Description Interval E-value
YecT COG3755
Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];
1-90 8.65e-30

Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];


Pssm-ID: 442969  Cd Length: 121  Bit Score: 102.46  E-value: 8.65e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078663924   1 MEMNETAAASFIKADTELNKVYKQLMTMLNQSE-KTLLIQAEKDWVKFRDSHCKFEASQYEGGSIKPLIYSTCLEQLTRK 79
Cdd:COG3755    31 AEMNACAAKEYQKADKELNKAYKALMKRLSAPEaKAALRKAQRAWIKYRDAECAFAAAAYEGGSIAPLAYASCLARLTQE 110

                          90
                  ....*....|.
gi 1078663924  80 RIAEIKASIKE 90
Cdd:COG3755   111 RTKELESLLEC 121
LprI pfam07007
Lysozyme inhibitor LprI; This family consists of several bacterial proteins of around 120 ...
 1-83 2.41e-17

Lysozyme inhibitor LprI; This family consists of several bacterial proteins of around 120 residues in length. Members of this family contain four highly conserved cysteine residues. Family members include lipoprotein LprI from Mycobacterium, which binds to and inhibits macrophage lysozyme, which may aid bacterial survival.


Pssm-ID: 429244  Cd Length: 103  Bit Score: 70.11  E-value: 2.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1078663924   1 MEMNETAAASFIKADTELNKVYKQLMTMLNQSEK--------TLLIQAEKDWVKFRDSHCKFEASQYEGGSIK-PLIYST 71
Cdd:pfam07007  12 AEMNACASAAYKAADAELNAAYKALLASADEREKaaldpearAALRAAQRAWIKYRDAECALVAALAGGGSGAgALAYAS 91

                          90
                  ....*....|..
gi 1078663924  72 CLEQLTRKRIAE 83
Cdd:pfam07007  92 CLAELTRERAAE 103
LprI COG4461
Lysozyme inhibitor LprI [Defense mechanisms];
13-86 1.93e-05

Lysozyme inhibitor LprI [Defense mechanisms];


Pssm-ID: 443559 [Multi-domain]  Cd Length: 109  Bit Score: 39.68  E-value: 1.93e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1078663924  13 KADTELNKVYKQLMTMLNQSEKTLLIQAEKDWVKFRDShCKFEASqyeggsikpliystCLEQLTRKRIAEIKA 86
Cdd:COG4461    44 ALDRRLAALYQQALAAAAAGDRAALRAEQRAWLKQRNA-CGKDRA--------------CLEDAYQERIAELQA 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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