|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12284 |
PRK12284 |
tryptophanyl-tRNA synthetase; Reviewed |
24-343 |
0e+00 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237036 [Multi-domain] Cd Length: 431 Bit Score: 553.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:PRK12284 15 PHLGNYAGAIRPAIAASRQPGVESFYFLADYHALIKCDDPARIQRSTLEIAATWLAAGLDPERVTFYRQSDIPEIPELTW 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAENGqEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFN 183
Cdd:PRK12284 95 LLTCVAGKGLLNRAHAYKAAVDKNVAAG-EDPDAGVTAGLFMYPVLMAADILMFNAHKVPVGRDQIQHIEMARDIAQRFN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 184 HRF-QELFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQPDESPLFEIYKAFS 262
Cdd:PRK12284 174 HLYgGEFFVLPEAVIEESVATLPGLDGRKMSKSYDNTIPLFAPREELKKAIFSIVTDSRAPGEPKDTEGSALFQLYQAFA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 263 TPSETAEFTQMLADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVGIRP 342
Cdd:PRK12284 254 TPEETAAFRQALADGIGWGDAKQRLFERIDRELAPMRERYEALIARPADIEDILLAGAAKARRIATPFLAELREAVGLRS 333
|
.
gi 1073549694 343 L 343
Cdd:PRK12284 334 L 334
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
24-343 |
5.10e-157 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 442.95 E-value: 5.10e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAaQNpDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:COG0180 16 LHLGNYLGALKNWVEL-QD-EYECFFFIADLHALTTPQDPEELRENTREVAADYLAAGLDPEKSTIFVQSDVPEHAELAW 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAENGqedpdfgVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFN 183
Cdd:COG0180 94 LLSCLTPLGELERMPQFKDKSAKNGKEN-------VNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLELTRDIARRFN 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 184 HRFQELFTLPEVKIDENVELLVGLDGR-KMSKSYGNTIPLWENDKKTQKSVNKIITNMKEP--GEPKQPDESPLFEIYKA 260
Cdd:COG0180 167 HRYGEVFPEPEALIPEEGARIPGLDGRkKMSKSYGNTINLLDDPKEIRKKIKSAVTDSERLryDDPGKPEVCNLFTIYSA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 261 FSTPSETAEFTQM-LADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVG 339
Cdd:COG0180 247 FSGKEEVEELEAEyRAGGIGYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEILAEGAEKARAIAAKTLAEVREAMG 326
|
....
gi 1073549694 340 IRPL 343
Cdd:COG0180 327 LLYF 330
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
24-339 |
1.63e-95 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 286.53 E-value: 1.63e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRaaQNPDTESFLFLADYHGIIKCHEQE-MIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELN 102
Cdd:TIGR00233 15 MHLGHYLGAIQTKWL--QQFGVELFICIADLHAITVKQTDPdALRKAREELAADYLAVGLDPEKTFIFLQSDYPEHYELA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 103 WILTCITAKGLMNRAHAYKAAVQANaengqedpdfGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRF 182
Cdd:TIGR00233 93 WLLSCQVTFGELKRMTQFKDKSQAE----------NVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRDLAERF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 183 NHRFQELFTLPEVKIDENVELLVGLDGRKMSKSYGNT-IPLWENDKKTQKSVNKIITNMKEP---GEPKQPDESPLFEIY 258
Cdd:TIGR00233 163 NKKFKNFFPKPESLISKFFPRLMGLSGKKMSKSDPNSaIFLTDTPKQIKKKIRKAATDGGRVtlfEHREKPGVPNLLVIY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 259 KAFSTPSE-----TAEFTQMLADGLAWGEAKKLSAAKINAELAELRERYNALTSnpSQIEEILQAGAQKARKEARELLDK 333
Cdd:TIGR00233 243 QYLSFFLIdddklKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERRAEIAE--EILDKILEPGAKKARETANKTLAD 320
|
....*.
gi 1073549694 334 VRDAVG 339
Cdd:TIGR00233 321 VYKAMG 326
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
24-294 |
1.02e-84 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 257.51 E-value: 1.02e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAaQNPDTESFLFLADYHGIIKCHEQ-EMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELN 102
Cdd:cd00806 12 LHLGHYLGAFRFWVWL-QEAGYELFFFIADLHALTVKQLDpEELRQNTRENAKDYLACGLDPEKSTIFFQSDVPEHYELA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 103 WILTCITAKGLMNRAHAYKAAVQanaeNGQEDPdfgveMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRF 182
Cdd:cd00806 91 WLLSCVVTFGELERMTGFKDKSA----QGESVN-----IGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDIARRF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 183 NHRFQELFTLPEVKIDEnVELLVGLDG--RKMSKSYG-NTIPLWENDKKTQKSVNKIIT---NMKEPGEPKQPDESPLFE 256
Cdd:cd00806 162 NKLYGEIFPKPAALLSK-GAFLPGLQGpsKKMSKSDPnNAIFLTDSPKEIKKKIMKAATdggRTEHRRDGGGPGVSNLVE 240
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1073549694 257 IYKAFSTPS--ETAEFTQMLADGLAWGEAKKLSAAKINAE 294
Cdd:cd00806 241 IYSAFFNDDdeELEEIDEYRSGGLGYGECKKLLAEAIQEF 280
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
24-296 |
6.90e-51 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 170.92 E-value: 6.90e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGnYVGAIRPAVRAaQNPDTESFLFLADYHGII----KCHEQEMIHQSTQAVAA--TWLACGLDPERTTFYRQSDIPE 97
Cdd:pfam00579 18 LHLG-YLVPLMKLRQF-QQAGHEVFFLIGDLHAIIgdpsKSPERKLLSRETVLENAikAQLACGLDPEKAEIVNNSDWLE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 98 VMELNWILTCITAKGLMNRAHAYKAaVQANAENGQedpdfGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARD 177
Cdd:pfam00579 96 HLELAWLLRDLGKHFSLNRMLQFKD-VKKRLEQGP-----GISLGEFTYPLLQAYDILLLKADLQPGGSDQWGNIELGRD 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 178 IAGRFNHRFqelFTLPEVKIdenVELLVGLDG-RKMSKSYGNTIpLWENDKKTqkSVNKIITNMK-EPGE------PKQP 249
Cdd:pfam00579 170 LARRFNKKI---FKKPVGLT---NPLLTGLDGgKKMSKSAGNSA-IFLDDDPE--SVYKKIQKAYtDPDRevrkdlKLFT 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1073549694 250 DESP-LFEIYKAFSTPSETAEFTQMLAD----GLAWGEAKKLSAAKINAELA 296
Cdd:pfam00579 241 FLSNeEIEILEAELGKSPYREAEELLARevtgLVHGGDLKKAAAEAVNKLLQ 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12284 |
PRK12284 |
tryptophanyl-tRNA synthetase; Reviewed |
24-343 |
0e+00 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237036 [Multi-domain] Cd Length: 431 Bit Score: 553.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:PRK12284 15 PHLGNYAGAIRPAIAASRQPGVESFYFLADYHALIKCDDPARIQRSTLEIAATWLAAGLDPERVTFYRQSDIPEIPELTW 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAENGqEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFN 183
Cdd:PRK12284 95 LLTCVAGKGLLNRAHAYKAAVDKNVAAG-EDPDAGVTAGLFMYPVLMAADILMFNAHKVPVGRDQIQHIEMARDIAQRFN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 184 HRF-QELFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQPDESPLFEIYKAFS 262
Cdd:PRK12284 174 HLYgGEFFVLPEAVIEESVATLPGLDGRKMSKSYDNTIPLFAPREELKKAIFSIVTDSRAPGEPKDTEGSALFQLYQAFA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 263 TPSETAEFTQMLADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVGIRP 342
Cdd:PRK12284 254 TPEETAAFRQALADGIGWGDAKQRLFERIDRELAPMRERYEALIARPADIEDILLAGAAKARRIATPFLAELREAVGLRS 333
|
.
gi 1073549694 343 L 343
Cdd:PRK12284 334 L 334
|
|
| PRK12556 |
PRK12556 |
tryptophanyl-tRNA synthetase; Provisional |
24-340 |
5.75e-168 |
|
tryptophanyl-tRNA synthetase; Provisional
Pssm-ID: 183592 [Multi-domain] Cd Length: 332 Bit Score: 470.74 E-value: 5.75e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:PRK12556 16 PHLGNYIGAIKPALQMAKNYEGKALYFIADYHALNAVHDPEQFRSYTREVAATWLSLGLDPEDVIFYRQSDVPEIFELAW 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAENGqEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFN 183
Cdd:PRK12556 96 ILSCLTPKGLMNRAHAYKAKVDQNKEAG-LDLDAGVNMGLYTYPILMAADILLFQATHVPVGKDQIQHIEIARDIATYFN 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 184 HRFQELFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQPDESPLFEIYKAFST 263
Cdd:PRK12556 175 HTFGDTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKDPETSALFTIYKEFAT 254
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1073549694 264 PSETAEFTQMLADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVGI 340
Cdd:PRK12556 255 EEEVQSMREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPSLLDEALEKGAERAREIAKPNLAEIKKAIGF 331
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
24-343 |
5.10e-157 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 442.95 E-value: 5.10e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAaQNpDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:COG0180 16 LHLGNYLGALKNWVEL-QD-EYECFFFIADLHALTTPQDPEELRENTREVAADYLAAGLDPEKSTIFVQSDVPEHAELAW 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAENGqedpdfgVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFN 183
Cdd:COG0180 94 LLSCLTPLGELERMPQFKDKSAKNGKEN-------VNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLELTRDIARRFN 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 184 HRFQELFTLPEVKIDENVELLVGLDGR-KMSKSYGNTIPLWENDKKTQKSVNKIITNMKEP--GEPKQPDESPLFEIYKA 260
Cdd:COG0180 167 HRYGEVFPEPEALIPEEGARIPGLDGRkKMSKSYGNTINLLDDPKEIRKKIKSAVTDSERLryDDPGKPEVCNLFTIYSA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 261 FSTPSETAEFTQM-LADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVG 339
Cdd:COG0180 247 FSGKEEVEELEAEyRAGGIGYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEILAEGAEKARAIAAKTLAEVREAMG 326
|
....
gi 1073549694 340 IRPL 343
Cdd:COG0180 327 LLYF 330
|
|
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
24-342 |
6.96e-145 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 412.17 E-value: 6.96e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVrAAQNpDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:PRK00927 14 LHLGNYLGAIKNWV-ELQD-EYECFFCIADLHALTVPQDPEELRENTRELAADYLACGIDPEKSTIFVQSHVPEHAELAW 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAENgqedpdfgVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFN 183
Cdd:PRK00927 92 ILNCITPLGELERMTQFKDKSAKQKEN--------VSAGLFTYPVLMAADILLYKADLVPVGEDQKQHLELTRDIARRFN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 184 HRFQELFTLPEVKIDENVELLVGLDGR--KMSKSYG---NTIPLWENDKKTQKSVNKIITNMK-----EPGEPKQPDESP 253
Cdd:PRK00927 164 NLYGEVFPVPEPLIPKVGARVMGLDGPtkKMSKSDPndnNTINLLDDPKTIAKKIKKAVTDSErlreiRYDLPNKPEVSN 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 254 LFEIYKAFsTPSETAEFTQMLAD-GLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLD 332
Cdd:PRK00927 244 LLTIYSAL-SGESIEELEAEYEAgGKGYGDFKKDLAEAVVEFLAPIRERYEELLADPAYLDEILAEGAEKARAVASKTLK 322
|
330
....*....|
gi 1073549694 333 KVRDAVGIRP 342
Cdd:PRK00927 323 EVREAMGLLR 332
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
24-339 |
1.63e-95 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 286.53 E-value: 1.63e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRaaQNPDTESFLFLADYHGIIKCHEQE-MIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELN 102
Cdd:TIGR00233 15 MHLGHYLGAIQTKWL--QQFGVELFICIADLHAITVKQTDPdALRKAREELAADYLAVGLDPEKTFIFLQSDYPEHYELA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 103 WILTCITAKGLMNRAHAYKAAVQANaengqedpdfGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRF 182
Cdd:TIGR00233 93 WLLSCQVTFGELKRMTQFKDKSQAE----------NVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRDLAERF 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 183 NHRFQELFTLPEVKIDENVELLVGLDGRKMSKSYGNT-IPLWENDKKTQKSVNKIITNMKEP---GEPKQPDESPLFEIY 258
Cdd:TIGR00233 163 NKKFKNFFPKPESLISKFFPRLMGLSGKKMSKSDPNSaIFLTDTPKQIKKKIRKAATDGGRVtlfEHREKPGVPNLLVIY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 259 KAFSTPSE-----TAEFTQMLADGLAWGEAKKLSAAKINAELAELRERYNALTSnpSQIEEILQAGAQKARKEARELLDK 333
Cdd:TIGR00233 243 QYLSFFLIdddklKEIYEAYKSGKLGYGECKKALIEVLQEFLKEIQERRAEIAE--EILDKILEPGAKKARETANKTLAD 320
|
....*.
gi 1073549694 334 VRDAVG 339
Cdd:TIGR00233 321 VYKAMG 326
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
24-294 |
1.02e-84 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 257.51 E-value: 1.02e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRPAVRAaQNPDTESFLFLADYHGIIKCHEQ-EMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELN 102
Cdd:cd00806 12 LHLGHYLGAFRFWVWL-QEAGYELFFFIADLHALTVKQLDpEELRQNTRENAKDYLACGLDPEKSTIFFQSDVPEHYELA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 103 WILTCITAKGLMNRAHAYKAAVQanaeNGQEDPdfgveMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRF 182
Cdd:cd00806 91 WLLSCVVTFGELERMTGFKDKSA----QGESVN-----IGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDIARRF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 183 NHRFQELFTLPEVKIDEnVELLVGLDG--RKMSKSYG-NTIPLWENDKKTQKSVNKIIT---NMKEPGEPKQPDESPLFE 256
Cdd:cd00806 162 NKLYGEIFPKPAALLSK-GAFLPGLQGpsKKMSKSDPnNAIFLTDSPKEIKKKIMKAATdggRTEHRRDGGGPGVSNLVE 240
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1073549694 257 IYKAFSTPS--ETAEFTQMLADGLAWGEAKKLSAAKINAE 294
Cdd:cd00806 241 IYSAFFNDDdeELEEIDEYRSGGLGYGECKKLLAEAIQEF 280
|
|
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
25-340 |
1.16e-67 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 215.49 E-value: 1.16e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 25 HLGNYVGAIRPAVrAAQNpDTESFLFLADYHGIIK-CHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:PRK12282 16 HLGHYVGSLKNRV-ALQN-EHEQFVLIADQQALTDnAKNPEKIRRNILEVALDYLAVGIDPAKSTIFIQSQIPELAELTM 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKAAVQANAengqedpdFGVEM--GLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGR 181
Cdd:PRK12282 94 YYMNLVTVARLERNPTVKTEIAQKG--------FGRSIpaGFLTYPVSQAADITAFKATLVPVGDDQLPMIEQTREIVRR 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 182 FNHRF-QELFTLPEVKIDEnVELLVGLDGR-KMSKSYGNTIPLWENDKKTQKSVNKIIT-----NMKEPGepkQPDESPL 254
Cdd:PRK12282 166 FNSLYgTDVLVEPEALLPE-AGRLPGLDGKaKMSKSLGNAIYLSDDADTIKKKVMSMYTdpnhiRVEDPG---KVEGNVV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 255 FEIYKAF-STPSETAEFTQML-ADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLD 332
Cdd:PRK12282 242 FTYLDAFdPDKAEVAELKAHYqRGGLGDVKCKRYLEEVLQELLAPIRERRAEFAKDPGYVLEILKAGSEKAREVAAQTLS 321
|
....*...
gi 1073549694 333 KVRDAVGI 340
Cdd:PRK12282 322 EVKDAMGL 329
|
|
| PLN02886 |
PLN02886 |
aminoacyl-tRNA ligase |
9-339 |
3.68e-62 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215478 [Multi-domain] Cd Length: 389 Bit Score: 203.12 E-value: 3.68e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 9 MSKKRVLTGVTTTGTPHLGNYVGAIRPAVrAAQNpDTESFLFLADYHGIIKCHEQEMIHQSTQAVAATWLACGLDPERTT 88
Cdd:PLN02886 44 ARKKRVVSGVQPTGSIHLGNYLGAIKNWV-ALQE-TYDTFFCVVDLHAITLPHDPRELGKATRSTAAIYLACGIDPSKAS 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 89 FYRQSDIPEVMELNWILTCITAKGLMNRAHAYKaavQANAENGQEDpdfgVEMGLFSYPILMTADILMFNANEVPVGRDQ 168
Cdd:PLN02886 122 VFVQSHVPAHAELMWLLSCSTPIGWLNKMIQFK---EKSRKAGDEN----VGVGLLTYPVLMASDILLYQADLVPVGEDQ 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 169 IQHVEMARDIAGRFNHRFQ------------ELFTLPEVKIDENVELLVGL-DG-RKMSKSY---GNTIPLWenDKKTQk 231
Cdd:PLN02886 195 KQHLELTRDIAERVNNLYGgrkwkklggrggSVFKVPEALIPPAGARVMSLtDGtSKMSKSApsdQSRINLL--DPPDV- 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 232 SVNKI-------ITNMkEPGEPKQPDESPLFEIYKAFSTPSEtaefTQMLAD--GLAWGEAKKLSAAKINAELAELRERY 302
Cdd:PLN02886 272 IANKIkrcktdsFPGL-EFDNPERPECNNLLSIYQLVTGKTK----EEVLAEcgDMRWGDFKPLLTDALIEHLSPIQVRY 346
|
330 340 350
....*....|....*....|....*....|....*..
gi 1073549694 303 NALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVG 339
Cdd:PLN02886 347 EEIMSDPSYLDSVLKEGADAAAEIADRTLANVYQAMG 383
|
|
| PRK12283 |
PRK12283 |
tryptophanyl-tRNA synthetase; Reviewed |
25-340 |
3.80e-55 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 183401 [Multi-domain] Cd Length: 398 Bit Score: 185.15 E-value: 3.80e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 25 HLGNYVGAIRPAVRAaQNpDTESFLFLADYHGIIKCHEQ-EMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNW 103
Cdd:PRK12283 16 HLGHYHGVLKNWVKL-QH-EYECFFFVADWHALTTHYETpEVIEKNVWDMVIDWLAAGVDPAQATLFIQSKVPEHAELHL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 104 ILTCITAKGLMNRAHAYKaavqanaeNGQE---DPDFGVeMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAG 180
Cdd:PRK12283 94 LLSMITPLGWLERVPTYK--------DQQEklkEKDLST-YGFLGYPLLQSADILIYRAGLVPVGEDQVPHVEMTREIAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 181 RFNH--------------------------------RFQE---------------------------LF---------TL 192
Cdd:PRK12283 165 RFNHlygrepgfeekaeaaikklgkkraklyhelrnAYQEegddealeqarallqeqqnlsmgdrerLFgylegagkiIL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 193 PE--VKIDENVElLVGLDGRKMSKSYGNTIPLWEndkkTQKSVNKIITNMK---------EPGEpkqPDESPLFEIYKAF 261
Cdd:PRK12283 245 PEpqALLTEASK-MPGLDGQKMSKSYGNTIGLRE----DPESVTKKIRTMPtdparvrrtDPGD---PEKCPVWQLHQVY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 262 STPsETAEFTQM--LADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEILQAGAQKARKEARELLDKVRDAVG 339
Cdd:PRK12283 317 SDE-ETKEWVQKgcRSAGIGCLECKQPVIDAILREQQPMRERAQKYEDDPSLVRAIVADGCEKARKVARETMRDVREAMG 395
|
.
gi 1073549694 340 I 340
Cdd:PRK12283 396 L 396
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
24-296 |
6.90e-51 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 170.92 E-value: 6.90e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGnYVGAIRPAVRAaQNPDTESFLFLADYHGII----KCHEQEMIHQSTQAVAA--TWLACGLDPERTTFYRQSDIPE 97
Cdd:pfam00579 18 LHLG-YLVPLMKLRQF-QQAGHEVFFLIGDLHAIIgdpsKSPERKLLSRETVLENAikAQLACGLDPEKAEIVNNSDWLE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 98 VMELNWILTCITAKGLMNRAHAYKAaVQANAENGQedpdfGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARD 177
Cdd:pfam00579 96 HLELAWLLRDLGKHFSLNRMLQFKD-VKKRLEQGP-----GISLGEFTYPLLQAYDILLLKADLQPGGSDQWGNIELGRD 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 178 IAGRFNHRFqelFTLPEVKIdenVELLVGLDG-RKMSKSYGNTIpLWENDKKTqkSVNKIITNMK-EPGE------PKQP 249
Cdd:pfam00579 170 LARRFNKKI---FKKPVGLT---NPLLTGLDGgKKMSKSAGNSA-IFLDDDPE--SVYKKIQKAYtDPDRevrkdlKLFT 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1073549694 250 DESP-LFEIYKAFSTPSETAEFTQMLAD----GLAWGEAKKLSAAKINAELA 296
Cdd:pfam00579 241 FLSNeEIEILEAELGKSPYREAEELLARevtgLVHGGDLKKAAAEAVNKLLQ 292
|
|
| Tyr_Trp_RS_core |
cd00395 |
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA ... |
25-285 |
1.09e-20 |
|
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS)/Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. These enzymes attach Tyr or Trp, respectively, to the appropriate tRNA. These class I enzymes are homodimers, which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173893 [Multi-domain] Cd Length: 273 Bit Score: 90.05 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 25 HLGNYVGaIRPAVRAaQNPDTESFLFLADYHGII----------KCHEQEMIHQSTQAVAATWLACGLD--PERTTFYRQ 92
Cdd:cd00395 14 HIGHLIG-LLTFRRF-QHAGHRPIFLIGGQTGIIgdpsgkkserTLNDPEEVRQNIRRIAAQYLAVGIFedPTQATLFNN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 93 SDIP---EVMELNWILTCITAKGLMNRahayKAAVQANAENGqedpdfgVEMGLFSYPILMTADILMFNANE----VPVG 165
Cdd:cd00395 92 SDWPgplAHIQFLRDLGKHVYVNYMER----KTSFQSRSEEG-------ISATEFTYPPLQAADFLLLNTTEgcdiQPGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 166 RDQIQHVEMARDIAGRFNhrfqeLFTLPEVKIdenVELLVGLDGRKMSKSYGNTIPLwENDKKTQKSVNKIITNMkepge 245
Cdd:cd00395 161 SDQWGNITLGRELARRFN-----GFTIAEGLT---IPLVTKLDGPKFGKSESGPKWL-DTEKTSPYEFYQFWINA----- 226
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1073549694 246 pkqpDESPLFEIYKAFSTPS--ETAEFTQMLADGLAWGEAKK 285
Cdd:cd00395 227 ----VDSDVINILKYFTFLSkeEIERLEQEQYEAPGYRVAQK 264
|
|
| PRK12285 |
PRK12285 |
tryptophanyl-tRNA synthetase; Reviewed |
78-335 |
2.76e-17 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237037 [Multi-domain] Cd Length: 368 Bit Score: 81.83 E-value: 2.76e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 78 LACGLDPERTTFYRQSDIPEVMELnwiltcitakglmnrahAYKAAVQANAENGQEDPDFGVE--MGLFSYPILMTADIL 155
Cdd:PRK12285 132 IALGFDPDKTEIYFQSENIKVYDL-----------------AFELAKKVNFSELKAIYGFTGEtnIGHIFYPATQAADIL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 156 MFNANE------VPVGRDQIQHVEMARDIAGRFN------------HRFqelftlpevkidenvelLVGLDGRKMSKSYG 217
Cdd:PRK12285 195 HPQLEEgpkptlVPVGIDQDPHIRLTRDIAERLHggygfikpsstyHKF-----------------MPGLTGGKMSSSKP 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 218 NT-IPLWENDKKTQKSVNKIITNMKEPGEPK-----QPDESPLFEIYKAFSTP--SETAEFTQMLADG-LAWGEAKKLSA 288
Cdd:PRK12285 258 ESaIYLTDDPETVKKKIMKALTGGRATLEEQrklggEPDECVVYELLLYHLEEddKELKEIYEECRSGeLLCGECKKEAA 337
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1073549694 289 AKINAELAELRERynaltsnpsqieeilqagaqkaRKEARELLDKVR 335
Cdd:PRK12285 338 EKIAEFLKEHQEK----------------------REEAREILEKYL 362
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
24-293 |
2.70e-12 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 66.09 E-value: 2.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAirPAVRAAQNPDTESFLFLADYHGII--KCHEQEMIHQSTQAVAATWLAC----------GLDPERTTFYR 91
Cdd:cd00805 14 LHLGHLVPL--MKLRDFQQAGHEVIVLIGDATAMIgdPSGKSEERKLLDLELIRENAKYykkqlkaildFIPPEKAKFVN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 92 QSDIpeVMELNWILTCITAKGL-MNRAHAykaavqANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQ 170
Cdd:cd00805 92 NSDW--LLSLYTLDFLRLGKHFtVNRMLR------RDAVKVRLEEEEGISFSEFIYPLLQAYDFVYLDVDLQLGGSDQRG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 171 HVEMARDIAGRFNHRFQELFTLPevkidenveLLVGLDGRKMSKSYGNTIplWENDKKTQKSVNKIITNmkepgepkQPD 250
Cdd:cd00805 164 NITLGRDLIRKLGYKKVVGLTTP---------LLTGLDGGKMSKSEGNAI--WDPVLDSPYDVYQKIRN--------AFD 224
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1073549694 251 EsPLFEIYKAFSTPS--ETAEFTQMLADGLAWGEAKKLSAAKINA 293
Cdd:cd00805 225 P-DVLEFLKLFTFLDyeEIEELEEEHAEGPLPRDAKKALAEELTK 268
|
|
| PRK08560 |
PRK08560 |
tyrosyl-tRNA synthetase; Validated |
24-314 |
3.97e-09 |
|
tyrosyl-tRNA synthetase; Validated
Pssm-ID: 236286 [Multi-domain] Cd Length: 329 Bit Score: 57.18 E-value: 3.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVGAIRpaVRAAQNPDTESFLFLADYHGII--KcHEQEMIHQSTQAVAATWLACGLDPERTTFYRQSDI---PEV 98
Cdd:PRK08560 43 IHLGHLLTMNK--LADLQKAGFKVTVLLADWHAYLndK-GDLEEIRKVAEYNKKVFEALGLDPDKTEFVLGSEFqldKEY 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 99 MELNWILTCITAkglMNRAHaykaavQANAENGQ--EDPDFGvEMglfSYPILMTADILMFNANeVPV-GRDQiQHVEM- 174
Cdd:PRK08560 120 WLLVLKLAKNTT---LARAR------RSMTIMGRrmEEPDVS-KL---VYPLMQVADIFYLDVD-IAVgGMDQ-RKIHMl 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 175 ARDIagrfnhrfqelftLPEVKIDENV----ELLVGLDG--RKMSKS-YGNTIPLWENDKKTQKSVNKIITnmkepgEPK 247
Cdd:PRK08560 185 AREV-------------LPKLGYKKPVcihtPLLTGLDGggIKMSKSkPGSAIFVHDSPEEIRRKIKKAYC------PPG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 248 QPDESPLFEIYKAFSTPSET-------------------AEFTQMLADG-LAWGEAKKLSAAKINAELAELRERynaLTS 307
Cdd:PRK08560 246 EVEGNPVLEIAKYHIFPRYDpfvierpekyggdleyesyEELERDYAEGkLHPMDLKNAVAEYLIEILEPVREY---LEE 322
|
....*..
gi 1073549694 308 NPSQIEE 314
Cdd:PRK08560 323 GPELLEL 329
|
|
| PRK13354 |
PRK13354 |
tyrosyl-tRNA synthetase; Provisional |
144-331 |
1.17e-08 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 237360 [Multi-domain] Cd Length: 410 Bit Score: 56.06 E-value: 1.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 144 FSYPILMTADILMFN-ANEVPV---GRDQIQHVEMARDIAGRFNHRFQELFTLPevkidenveLLVGLDGRKMSKSYGNT 219
Cdd:PRK13354 168 FFYPLLQAYDFVHLNrKEDVDLqigGTDQWGNILMGRDLQRKLEGEEQFGLTMP---------LLEGADGTKMGKSAGGA 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 220 IplWENDKKT------QKSVNkiitnmkepgepkQPDEsplfEIYK-----AFSTPSETAEFTQMLADGLAWGEAKKLSA 288
Cdd:PRK13354 239 I--WLDPEKTspyefyQFWMN-------------IDDR----DVVKylklfTDLSPDEIDELEAQLETEPNPRDAKKVLA 299
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1073549694 289 AKI------NAELAELRERYNAL----------------TSNPSQIEEIL-QAGAQKARKEARELL 331
Cdd:PRK13354 300 EEItkfvhgEEAAEEAEKIFKALfsgdvkplkdiptfevSAETKNLVDLLvDLGLEPSKREARRLI 365
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
24-332 |
1.74e-07 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 52.40 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 24 PHLGNYVgAIRpAVRAAQNPDTESFLFLADYHGII--KCHEQEMIHQSTQAVAATW-------LACGLDPERTTFYRQSD 94
Cdd:TIGR00234 45 LHLGHLV-PLL-KLRDFQQAGHEVIVLLGDFTALIgdPTGKSEVRKILTREEVQENaenikkqIARFLDFEKAKFVYNSE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 95 IPEVMELNWILTCITAKGLMNRAHAYKAAVqanaENGQEDPDFgVEmglFSYPILMTADILMFNANEVPVGRDQIQHVEM 174
Cdd:TIGR00234 123 WLLKLNYTDFIRLLGKIFTVNRMLRRDAFS----SRFEENISL-HE---FIYPLLQAYDFVYLNVDLQLGGSDQWFNIRK 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 175 ARDIAGRFNHRFQELFTLPevkidenveLLVGLDGRKMSKSYGNTIPLwenDKKTQKSVNKIItnmkepgepKQPDESpL 254
Cdd:TIGR00234 195 GRDLARENLPSLQFGLTVP---------LLTPADGEKMGKSLGGAVSL---DEGKYDFYQKVI---------NTPDEL-V 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 255 FEIYKAFSTPSETAEFTQMLADGLAWGEAKKLSAAKI-------NAELAELRERYNALTSNPSQIE-------------- 313
Cdd:TIGR00234 253 KKYLKLFTFLGLEEIEQLVELKGPNPREVKENLALEItkyvhgpEAALAAEEISEAIFSGGLNPDEvpifrpekfggpit 332
|
330 340
....*....|....*....|..
gi 1073549694 314 ---EILQAGAQKARKEARELLD 332
Cdd:TIGR00234 333 ladLLVLSGLFPSKSEARRDIK 354
|
|
| class_I_aaRS_core |
cd00802 |
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA ... |
143-215 |
4.89e-05 |
|
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA synthetase (aaRS) catalytic core domain. These enzymes are mostly monomers which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173901 [Multi-domain] Cd Length: 143 Bit Score: 42.85 E-value: 4.89e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1073549694 143 LFSYPILMTADILMFNANE---VPVGRDQIQHVEMARDIAGRFNhrfqelftLPEVKIDENVELLVGLDGRKMSKS 215
Cdd:cd00802 75 DVEYMFLQAADFLLLYETEcdiHLGGSDQLGHIELGLELLKKAG--------GPARPFGLTFGRVMGADGTKMSKS 142
|
|
| TyrS |
COG0162 |
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tyrosyl-tRNA ... |
144-229 |
7.99e-05 |
|
Tyrosyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tyrosyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439932 [Multi-domain] Cd Length: 409 Bit Score: 44.25 E-value: 7.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1073549694 144 FSYPILMTADIL-MFNANEVPV---GRDQ---IQhveMARDIAGRFNHRFQELFTLPevkidenveLLVGLDGRKMSKSY 216
Cdd:COG0162 166 FSYPLLQGYDFVeLYRRYGCDLqlgGSDQwgnIL---AGRELQRRYGGEPQFGLTMP---------LLTGADGTKMGKSE 233
|
90
....*....|...
gi 1073549694 217 GNTIPLweNDKKT 229
Cdd:COG0162 234 GNAIWL--DEEKT 244
|
|
| |
