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Conserved domains on  [gi|1072318580|ref|WP_069940640|]
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MULTISPECIES: type II toxin-antitoxin system RelB family antitoxin [Exiguobacterium]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF6290 pfam19807
Family of unknown function (DUF6290); This family of proteins is functionally uncharacterized, ...
 1-71 5.01e-23

Family of unknown function (DUF6290); This family of proteins is functionally uncharacterized, they are predominantly found in bacteria but also in viruses. Proteins in this family are approximately 80 amino acids in length and presumably contain a ribbon-helix-helix DNA-binding motif.


:

Pssm-ID: 437639  Cd Length: 72  Bit Score: 82.99  E-value: 5.01e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1072318580  1 MSTISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDEIDLQLYHDSMAA-HRKKSEAISFGDMMKEL 71
Cdd:pfam19807  1 MSTISVRLNEEEEELIKKYAKLKGISLSELIRQALLEKIEDEYDLKIYEEYAAEkKKGDPKTYSHDEVKKEL 72
 
Name Accession Description Interval E-value
DUF6290 pfam19807
Family of unknown function (DUF6290); This family of proteins is functionally uncharacterized, ...
 1-71 5.01e-23

Family of unknown function (DUF6290); This family of proteins is functionally uncharacterized, they are predominantly found in bacteria but also in viruses. Proteins in this family are approximately 80 amino acids in length and presumably contain a ribbon-helix-helix DNA-binding motif.


Pssm-ID: 437639  Cd Length: 72  Bit Score: 82.99  E-value: 5.01e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1072318580  1 MSTISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDEIDLQLYHDSMAA-HRKKSEAISFGDMMKEL 71
Cdd:pfam19807  1 MSTISVRLNEEEEELIKKYAKLKGISLSELIRQALLEKIEDEYDLKIYEEYAAEkKKGDPKTYSHDEVKKEL 72
COG4710 COG4710
Predicted DNA-binding protein with an HTH domain [General function prediction only];
1-74 4.25e-09

Predicted DNA-binding protein with an HTH domain [General function prediction only];


Pssm-ID: 443745  Cd Length: 76  Bit Score: 47.59  E-value: 4.25e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1072318580  1 MSTISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDEIDLQLYHDSMAAHRK-KSEAISFGDMMKELDLE 74
Cdd:COG4710    1 MKMLSIRLPEELEARLDALAKRTGRSKSFYVREAIEEYLDDLEDYYLAEERLERVRAgREKTYSLEEVERDLGLE 75
RHH_MobB-like cd22234
ribbon-helix-helix domain of mobilization protein MobB and similar proteins; This subfamily ...
 4-42 5.18e-03

ribbon-helix-helix domain of mobilization protein MobB and similar proteins; This subfamily includes Pseudomonas syringae mobilization protein MobB, and mostly archaeal uncharacterized CopG family proteins. These proteins have a typical ribbon-helix-helix (RHH), similar to plasmid-encoded transcriptional repressor CopG, the protein that is encoded by the promiscuous streptococcal plasmid pMV158 and is involved in the control of plasmid copy number.


Pssm-ID: 409024  Cd Length: 44  Bit Score: 31.46  E-value: 5.18e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 1072318580  4 ISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDE 42
Cdd:cd22234    4 TFLRLREEDKKLIKELAKYYDISESDVVRIALKELAKEH 42
 
Name Accession Description Interval E-value
DUF6290 pfam19807
Family of unknown function (DUF6290); This family of proteins is functionally uncharacterized, ...
 1-71 5.01e-23

Family of unknown function (DUF6290); This family of proteins is functionally uncharacterized, they are predominantly found in bacteria but also in viruses. Proteins in this family are approximately 80 amino acids in length and presumably contain a ribbon-helix-helix DNA-binding motif.


Pssm-ID: 437639  Cd Length: 72  Bit Score: 82.99  E-value: 5.01e-23
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1072318580  1 MSTISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDEIDLQLYHDSMAA-HRKKSEAISFGDMMKEL 71
Cdd:pfam19807  1 MSTISVRLNEEEEELIKKYAKLKGISLSELIRQALLEKIEDEYDLKIYEEYAAEkKKGDPKTYSHDEVKKEL 72
COG4710 COG4710
Predicted DNA-binding protein with an HTH domain [General function prediction only];
1-74 4.25e-09

Predicted DNA-binding protein with an HTH domain [General function prediction only];


Pssm-ID: 443745  Cd Length: 76  Bit Score: 47.59  E-value: 4.25e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1072318580  1 MSTISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDEIDLQLYHDSMAAHRK-KSEAISFGDMMKELDLE 74
Cdd:COG4710    1 MKMLSIRLPEELEARLDALAKRTGRSKSFYVREAIEEYLDDLEDYYLAEERLERVRAgREKTYSLEEVERDLGLE 75
RHH_MobB-like cd22234
ribbon-helix-helix domain of mobilization protein MobB and similar proteins; This subfamily ...
 4-42 5.18e-03

ribbon-helix-helix domain of mobilization protein MobB and similar proteins; This subfamily includes Pseudomonas syringae mobilization protein MobB, and mostly archaeal uncharacterized CopG family proteins. These proteins have a typical ribbon-helix-helix (RHH), similar to plasmid-encoded transcriptional repressor CopG, the protein that is encoded by the promiscuous streptococcal plasmid pMV158 and is involved in the control of plasmid copy number.


Pssm-ID: 409024  Cd Length: 44  Bit Score: 31.46  E-value: 5.18e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 1072318580  4 ISVRLDDQDTRLIKEYAKAKNITISTLVRDAVLDRIEDE 42
Cdd:cd22234    4 TFLRLREEDKKLIKELAKYYDISESDVVRIALKELAKEH 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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