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Conserved domains on  [gi|1067529743|gb|AOQ26618|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Lerista allanae]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-226 8.15e-132

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 378.77  E-value: 8.15e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00124  232 AAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSG 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00124  312 AMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPT 391

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGP 226
Cdd:MTH00124  392 TIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-226 8.15e-132

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 378.77  E-value: 8.15e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00124  232 AAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSG 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00124  312 AMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPT 391

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGP 226
Cdd:MTH00124  392 TIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-227 3.37e-44

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 154.08  E-value: 3.37e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:COG1008   248 AGVLLKMGGYGLLRFALPLFPEASAYFAPLLAaLGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQ 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:COG1008   328 GAVLQMVSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNP 407

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGPF 227
Cdd:COG1008   408 WLAILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLLDLI 475
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-169 9.27e-39

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 135.52  E-value: 9.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:pfam00361 121 AATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQA 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLA-NTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:pfam00361 201 AIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASW 280

                         170
                  ....*....|
gi 1067529743 160 LTITMTGLGT 169
Cdd:pfam00361 281 IFLVLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-227 2.02e-38

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 138.53  E-value: 2.02e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:TIGR01972 242 AGVLLKMGTYGFLRFNLPLFPDASLYFAPVLAaLGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGIS 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:TIGR01972 322 GAVFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNP 401

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLP-THITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGPF 227
Cdd:TIGR01972 402 VVAFLAALGIVLAAAYMLTLYKRVFFGELSnPEVAEFPDLNGREIAVLAPLVVLILFLGLYPNPLLDLT 470
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-226 8.15e-132

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 378.77  E-value: 8.15e-132
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00124  232 AAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHMGLVIAATMIQTPWSLSG 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00124  312 AMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTINLMGELTIMTSLFNWSPT 391

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGP 226
Cdd:MTH00124  392 TIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELISGT 457
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-227 1.66e-124

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 360.39  E-value: 1.66e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00068  232 AAVLLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHMGLVIAAALIQTPWSFSG 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00068  312 AIILMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPNLWGELTIMVSLFNWSNW 391

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGPF 227
Cdd:MTH00068  392 TILITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELISGMF 458
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-226 2.86e-118

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 344.57  E-value: 2.86e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00110  232 AAILLKLGGYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSFMG 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00110  312 ATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVIMSSFSWSNI 391

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGP 226
Cdd:MTH00110  392 TIILMGLNMLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILGP 457
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-225 7.69e-98

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 292.63  E-value: 7.69e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00127  233 AAVLLKLGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHMGLVAGGILIQTPWGFTG 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00127  313 ALILMIAHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPNLMGELMIITSLFNWSPW 392

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMG 225
Cdd:MTH00127  393 TLALTGLGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELIWG 457
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-223 5.16e-91

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 274.51  E-value: 5.16e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00206  228 AGVLLKLGGYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHMSLVTAGILSGSPWGFKG 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00206  308 ALLLMIAHGLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPNLFGELLIITSLFSWSNF 387

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLI 223
Cdd:MTH00206  388 TLPLLGLGFLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-224 4.76e-76

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 236.41  E-value: 4.76e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLN-PLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:MTH00044  233 AAILLKLGGYGLIRLINLFSlPSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGHMSLVAAGIFSGTNWGIN 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:MTH00044  313 GALILMIAHGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLPNLIGELLIISSIISWSI 392

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIM 224
Cdd:MTH00044  393 LSFPIIGLATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNIIL 457
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-224 4.23e-67

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 213.09  E-value: 4.23e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00163  220 AGVLLKLGGYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHMGLVLGGLMTFSYWGLMG 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00163  300 SLLMMIGHGLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLNLLGEISLINSLISWSKL 379

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIM 224
Cdd:MTH00163  380 SMIFLMLLSFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLFM 443
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-225 7.05e-64

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 203.92  E-value: 7.05e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00150  191 AGILLKLGGYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHMSLVLAGVLSNTSWGWVG 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00150  271 ALIMMVSHGFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLNLLSEIMIFPSLISYSPW 350

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMG 225
Cdd:MTH00150  351 FFVPLGLMVFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLLFM 415
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-224 9.76e-57

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 186.34  E-value: 9.76e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00205  224 AGVLLKLGGYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHMGLMVVGVFSNTSWGMNG 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00205  304 AIIMMVAHGLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLNLASEILLIMSLLSSSKI 383

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIM 224
Cdd:MTH00205  384 SGIPLSLISFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIFI 447
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-223 6.93e-55

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 181.48  E-value: 6.93e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00014  226 AGILLKLGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHMGLMTAGIMSNTSWGWQG 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00014  306 ALAMMIAHGLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSINLLSEIMLLTSILSSSLS 385

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1067529743 161 TITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLI 223
Cdd:MTH00014  386 TAILLAITSFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLI 448
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-227 3.37e-44

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 154.08  E-value: 3.37e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:COG1008   248 AGVLLKMGGYGLLRFALPLFPEASAYFAPLLAaLGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLLGIFALNPLGLQ 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:COG1008   328 GAVLQMVSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTSGFVGEFLVLLGAFQVNP 407

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGPF 227
Cdd:COG1008   408 WLAILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLLGLYPQPLLDLI 475
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-169 9.27e-39

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 135.52  E-value: 9.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:pfam00361 121 AATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYGIQA 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLA-NTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:pfam00361 201 AIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASW 280

                         170
                  ....*....|
gi 1067529743 160 LTITMTGLGT 169
Cdd:pfam00361 281 IFLVLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-227 2.02e-38

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 138.53  E-value: 2.02e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:TIGR01972 242 AGVLLKMGTYGFLRFNLPLFPDASLYFAPVLAaLGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGIFSFNELGIS 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:TIGR01972 322 GAVFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTSGFVGEFLILLGSFKVNP 401

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLP-THITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGPF 227
Cdd:TIGR01972 402 VVAFLAALGIVLAAAYMLTLYKRVFFGELSnPEVAEFPDLNGREIAVLAPLVVLILFLGLYPNPLLDLT 470
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-228 2.73e-37

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 135.72  E-value: 2.73e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK05846  250 AGILLKMGAYGLLRFSLPLFPDASHEFAPIIItLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTLGIFAGNQLGIQ 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:PRK05846  330 GAIFQMISHGLSSAALFLLVGVLYDRLHTRDIADYGGLAKVMPVLAAFFLFFAMASLGLPGTSGFVGEFLILLGSFQVNP 409

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGPFS 228
Cdd:PRK05846  410 VIAFIATTGLILAAVYSLWLYQRVMFGPVKNEVAKLKDLNGRELLILLPLVALLLLLGVYPKPLLDVIH 478
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-226 6.33e-37

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 134.81  E-value: 6.33e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFI-MLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:MTH00204  248 AGILLKLGGYGFLRFSWPLFPAASEYFAPLIvMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHMGLVPLGLFTHTIEGLV 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:MTH00204  328 AAVFLMLAHGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSCNFVGEFFSLLAAFEYSL 407

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMGP 226
Cdd:MTH00204  408 GLGVLVTSGMVWSAAYSLYLYNRISFGGGSNYLLFSRDLNRRELLAILPLIIAIFLLGIVPFIIIDL 474
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-180 4.74e-36

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 132.48  E-value: 4.74e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:MTH00217  245 AGVLLKLGGYGFIRFSWPLLPEASEYFSPLIQtLSLLAIIYGSLTTCRQVDLKRIIAYSSVAHMGLVTLGIFSHTIQGLV 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:MTH00217  325 AAIFLMLAHGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSCNFVGEFLSLLAAFEYSY 404

                         170       180
                  ....*....|....*....|.
gi 1067529743 160 LTITMTGLGTLLTATYSLYMF 180
Cdd:MTH00217  405 IVGVLASLGMVLSAGYSIYLY 425
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-224 6.93e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 126.96  E-value: 6.93e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRIT-PMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:MTH00226  269 AGILLKLGGYGLVRLSwPILPLGAQNLAPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGLT 348

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:MTH00226  349 GSIFIMLAHGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSGNFIGEYLSILSSFNWNP 428

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1067529743 160 LTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIM 224
Cdd:MTH00226  429 IIGVFVCSGVILSAVYSFYFANRVTFGAPGNLITFARDVNRREFYITASMVFFAFLIGIYPIFIL 493
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-179 7.54e-21

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 90.39  E-value: 7.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIML-AMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:CHL00011  250 AGILLKMGAYGLIRINMELLPHAHSIFSPWLVIvGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLN 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERThsRTLLLAR--GLQLILPLMTTWWLMANLMNMALPPTINITGELL----IMAS 153
Cdd:CHL00011  330 GAILQIISHGFIGAALFFLAGTSYDRI--RLVYLDEmgGIAIPMPKIFTMFSSFSMASLALPGMSGFVAELIvffgIITS 407

                         170       180
                  ....*....|....*....|....*....
gi 1067529743 154 TFNWSNLTITMT---GLGTLLTATYSLYM 179
Cdd:CHL00011  408 QKYLLMPKILITfvmAIGMILTPIYLLSM 436
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-221 1.75e-20

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 88.99  E-value: 1.75e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFimLAMWGIIMT---STICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWS 77
Cdd:PRK06473  244 AGVLLKLGTYGLLRFGVGLFPEAWVYLAPW--LATWAVVSVlygASCAIAQKDMKKMVAYSSIGHMGYILLAAAAATPLS 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  78 LTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGL---QLILPLMTTWWLMANLMNMALPPTINITGELLIMAST 154
Cdd:PRK06473  322 ILAAVFQMISHGLISALLFLLVGVVYKKTGSRDVDVLRGLlnpERGLPITGSLMILGVMASAGIPGMVGFIAEFLVFRGS 401

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743 155 FNWSNLTITMTGLGTLLTATYSLYMFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQ 221
Cdd:PRK06473  402 FPIFPVQTLLCMIGTGLTAVYFLLLVNRVFFGRLTAELSNLPRVLWSERLPALVLAVLIVVLGIQPS 468
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-184 2.17e-20

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 88.67  E-value: 2.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRI-TPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSL 78
Cdd:COG0651   244 SGLLTKVGVYAILRVlTLLFGADPALFLGTLLLvLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGL 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  79 TGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWS 158
Cdd:COG0651   324 AGALFHLLNHALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAG 403

                         170       180
                  ....*....|....*....|....*..
gi 1067529743 159 NLTITMTGL-GTLLTATYSLYMFLMTQ 184
Cdd:COG0651   404 AWLLAAVLLlSSLLTLAYFVRIFGRAQ 430
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-224 5.20e-20

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 87.78  E-value: 5.20e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYP-FIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK12561  224 AGVLLKMGGYALIRFNVQMLPDAHVYFAPaLAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGIAAFTDLGIS 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHsrTLLLAR--GLQLILPLMTTWWLMANLMNMALPPTINITGELLIM------ 151
Cdd:PRK12561  304 GAMLQMISHGLIAAALFFLTGVTYERTH--TLSIPNmgGLAKVMPKTFALFTASSMASLALPGMSGFVSELTVFlgitss 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743 152 ---ASTFNwsNLTITMTGLGTLLTATYSLYM----FLMTQRGKLPTHITQTEpTHTREHLLMALHTMPMLLLMLKPQLIM 224
Cdd:PRK12561  382 dvySSTFR--TITILLAAVGLILTPIYLLSMlrrvFYGPRSELLPALAVVED-AKPRELFIALSLLVPIIGIGFYPKLAT 458
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-178 3.75e-19

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 84.96  E-value: 3.75e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYypfIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:MTH00094  190 AGLLLKLGTAGFLRILGSLNFVYNNFW---IIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHMSFLLLSLVYMSMSGKLS 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:MTH00094  267 GLMMMLAHGYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLSFFSEFLIISNSFMKNKF 346

                         170
                  ....*....|....*...
gi 1067529743 161 TITMTGLGTLLTATYSLY 178
Cdd:MTH00094  347 SFFFIFFYFLVSFYYSLF 364
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-179 1.69e-18

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 83.60  E-value: 1.69e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYP-FIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK02546  252 AGILLKMGGYALLRMNAGMLPDAHAQFAPlLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFTDLGTS 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIM-------A 152
Cdd:PRK02546  332 GAMLQMISHGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMSGFVAELMVFvgfatsdA 411

                         170       180
                  ....*....|....*....|....*..
gi 1067529743 153 STFNWSNLTITMTGLGTLLTATYSLYM 179
Cdd:PRK02546  412 YTLPFRVVVVFLAAVGVILTPIYLLSM 438
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-175 2.62e-14

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 71.06  E-value: 2.62e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRIT----PMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQW 76
Cdd:PRK08375  241 SGLVTKVAVYALIRIYftvfGGDFRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLALLTPL 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  77 SLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGEL-LIMASTF 155
Cdd:PRK08375  321 ALAAGLLHLLHHALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWyLVVGAVE 400

                         170       180
                  ....*....|....*....|
gi 1067529743 156 NWSNLTITMTGLGTLLTATY 175
Cdd:PRK08375  401 AGQWLVLAVLLASSLLALLY 420
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
3-191 3.95e-14

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 70.90  E-value: 3.95e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   3 ILLKLGGYGIIRITPMLNPLTTNMYYPfiMLAMWG---IIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK07363  246 VLAKLGTYGLLRFGLQLFPQTWSLVAP--GLAIIGtisVIYGALSAIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLI---LPLMTTWWLMANLMNMALPPTINITGELLIMASTFN 156
Cdd:PRK07363  324 GAVAQMISHGLILALLFHLVGIVERKVGTRDLDVLNGLMNPirgLPLTSALLVLAGMASAGIPGLVGFVAEFIVFQGSFS 403

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1067529743 157 WSNLTITMTGLGTLLTATYSLYMFLMTQRGKLPTH 191
Cdd:PRK07363  404 TFPIPTLLCIVASGLTAVYFVILLNRTCFGRLDNK 438
PRK12650 PRK12650
DUF4040 family protein;
1-177 5.05e-13

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 67.76  E-value: 5.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTnMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:PRK12650  247 AAAVVKAGIYLLLRFSPVFHDVAV-WNWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATIGVGTPFALTA 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTIN-ITGELLIMA------S 153
Cdd:PRK12650  326 AVVHTLAHALFKSSLFMLIGVVDHQAGTRDIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFGfVSKEGMLTAfleapgG 405

                         170       180
                  ....*....|....*....|....
gi 1067529743 154 TFNWSNLTITMtGLGTLLTATYSL 177
Cdd:PRK12650  406 NAGVVLLLVGA-ALGAVFTFAYSA 428
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-150 4.53e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 64.61  E-value: 4.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRI-------TPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQ 73
Cdd:PRK12667  262 SGLVVNVGAYAIIRFlytifgiSPSLIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIG 341

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743  74 TQWSLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLI 150
Cdd:PRK12667  342 TQLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLL 418
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 1-218 8.95e-11

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 60.94  E-value: 8.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLnplttnMYYPFIMLAMWGI-----IMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQtq 75
Cdd:COG1009   250 AATMVKAGVYLLARLSPLF------ALSPVWLTVVAIIgaitaLFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG-- 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  76 wSLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTF 155
Cdd:COG1009   322 -AYVAALFHLLTHAFFKALLFLGAGSVIHATGTRDIRKMGGLRKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAAL 400

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743 156 NWSNLTITMTGLGTL---LTATYSLYMFLMTQRGKLPTHitqtEPTHTRE-HLLMalhTMPMLLLML 218
Cdd:COG1009   401 EAGGLGPLLLAVALLgafLTAFYSFRLFFLVFFGKPRPK----TPKHPHEsPWLM---TLPLVVLAV 460
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 2-225 1.08e-09

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 57.63  E-value: 1.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   2 AILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAM--WGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK06458  254 GVLLNVALYAVLRYYILIDAAIGSDFPGRLLLIFglLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIF 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLmTTWWLMANLMNMA-LPPTINITGELLIMASTFNWS 158
Cdd:PRK06458  334 AALLHMLNHSLTKSAIFFASGNVLQKYGTRDINVIRGLLKVSPL-TGWGLMLGALAIAgMPPFGVFISEFLILTAGLARG 412

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743 159 NLTITMTGLGTLLTATYSLymFLMTQRgklptHITQTEPTHTREHLLMALHTMPMLLLMLKPqLIMG 225
Cdd:PRK06458  413 PLLIAILLLLLLTLAFAAL--VRRVAG-----MVFGEPPEAVNRGDLGWLTTSPMFVHLVLV-LVLG 471
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 2-170 8.04e-09

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 55.31  E-value: 8.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   2 AILLKLGGYGIIRitpmLNPLTTNMYYPFIMLAMWG---IIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSL 78
Cdd:PRK12647  235 ATMVKAGIYLLAR----LNPVLGGTPLWQTILPLFGgltMLTGALLAVRQTDLKLILAYSTVSALGTLVMLLGLGSELAI 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  79 TGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWS 158
Cdd:PRK12647  311 KAAVLFLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLRRAMPITAAAALLAALSMAGLPPLFGFLAKELIYEALLEAP 390

                         170
                  ....*....|..
gi 1067529743 159 NLTITMTGLGTL 170
Cdd:PRK12647  391 LWSLILTVAAVL 402
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-182 3.96e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 52.90  E-value: 3.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTT-----NMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQ 75
Cdd:PRK06589  249 AVIVVKTGLFCIYKILLYIFGLSYlqrifAEFNWLIFIPIVSIFYSSLKALKTDNIKKILAYSTISQLSLALLSAFILTP 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  76 WSLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTF 155
Cdd:PRK06589  329 KALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGIPIFSGFISKFLILLAAS 408

                         170       180
                  ....*....|....*....|....*....
gi 1067529743 156 NWSN--LTITMTGLGTLLTATYSLYMFLM 182
Cdd:PRK06589  409 EQNQpwLSIIVMLVVIASSILSALYLLKI 437
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 1-96 1.44e-07

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 51.31  E-value: 1.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLT--TNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSL 78
Cdd:PRK08377  245 SAFVVKAGLYAMARILYLMQNANgwSSVLKLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIALALALGTQAGV 324

                          90
                  ....*....|....*...
gi 1067529743  79 TGAIVLMVAHGLTSSMLF 96
Cdd:PRK08377  325 DAGVFHMINHAIVKALLF 342
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-96 5.35e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 49.75  E-value: 5.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPML--NPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSL 78
Cdd:PRK08676  245 SGTVLNIGIYGILRLSALLrqSGAAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLAL 324

                          90
                  ....*....|....*...
gi 1067529743  79 TGAIVLMVAHGLTSSMLF 96
Cdd:PRK08676  325 FWMLFHMLAHSLVKSGLF 342
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 30-154 6.94e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 49.35  E-value: 6.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  30 FIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTGAIVLMVAHGLTSSMLFCLANT---NYERT 106
Cdd:PRK12662  282 FMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSisyHFGTT 361

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1067529743 107 HSRTLLlarGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMAST 154
Cdd:PRK12662  362 KLEDCL---NLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAF 406
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 1-178 3.09e-06

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 47.61  E-value: 3.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTnMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTG 80
Cdd:PRK12644  242 AAAMVKAGIYLVARLAPGFADVPV-WRPTVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLVGIGTRDAALA 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMAnLMNMA-LPPTINITG-----ELLIMAST 154
Cdd:PRK12644  321 GLAMLLAHALFKAALFLVVGIIDHSTGTRDIRKLSGLGRRQPVLAVVAALA-AASMAgLPPLLGFVAkeaalEAVLHDGA 399

                         170       180
                  ....*....|....*....|....*
gi 1067529743 155 FNW-SNLTITMTGLGTLLTATYSLY 178
Cdd:PRK12644  400 LGPaGPVVLAGIVLGSILTVAYSLR 424
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-177 5.22e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 46.48  E-value: 5.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIM-LAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK07691  248 GALLTKVGVYAIARTFTLFFSHDTSFTHYLILiLALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVGVAMMTESGMI 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:PRK07691  328 GAIYYLIHDMIVKAALFLLIGIMIKITGTTDLKKMGGLIKRYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGF 407

                         170
                  ....*....|....*...
gi 1067529743 160 LTITMTGLGTLLTATYSL 177
Cdd:PRK07691  408 YVSGIIVLLSSLLVLYSV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 46-225 1.75e-05

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 45.11  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  46 LRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTGAIVLMVAHGLTSSMLF-CLANTNYERTHSRTLLLARGLQLILPLM 124
Cdd:COG1007   288 LAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMNLGAFaVILLLSRKGGEAEEIEDLAGLARRSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743 125 TtwWLMANLM-NMA-LPPTINITGELLIMASTFNWSNLTITMTG-LGTLLTATYSL----YMFLMTQRGKLPTHItqteP 197
Cdd:COG1007   368 A--LAMTIFLlSLAgIPPTAGFFGKFYVFSAAVEAGLYWLAVIAvLNSVISAYYYLrvvkAMYFDEPEEEAPISA----P 441

                         170       180
                  ....*....|....*....|....*...
gi 1067529743 198 THTRehLLMALHTMPMLLLMLKPQLIMG 225
Cdd:COG1007   442 PGLR--VALVIAALLVLLLGIFPGPLLD 467
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 3-155 1.81e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 45.11  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   3 ILLKLGGYGIIRItpMLNPLTTNMYYPFIML------AMWGIIMTsticLRQTDLKSLIAYSSVSHMGL--------VIA 68
Cdd:PRK08667  246 VMLKVAVYGLVRF--LMDVLSPELWWGVLILlagsisALLGVIYA----LKEHDLKGLLAYSSIENIGIilmgiglyVIF 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  69 ACLIQTQW---SLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINIT 145
Cdd:PRK08667  320 GVYGLDTLallALGGALFHSLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSALFLVGAVSIAALPPFNGFA 399

                         170
                  ....*....|
gi 1067529743 146 GELLIMASTF 155
Cdd:PRK08667  400 SELLLYESFF 409
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
6-92 1.82e-05

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 44.81  E-value: 1.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   6 KLGGYGII-RITPM-LNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTGAIV 83
Cdd:PRK05777  247 KIAAFAVLlRLLVVaFGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLF 326


                  ....*....
gi 1067529743  84 LMVAHGLTS 92
Cdd:PRK05777  327 YLLAYLFMT 335
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 1-171 3.09e-05

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 44.19  E-value: 3.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLV---IAACLIQTQWS 77
Cdd:PRK06525  246 AASMVKVGVYIFARAIQSMGPIPHVIGYVGAVMAIVTLLYGFLMYLPQQDMKRLLAYSTITQLGYMffgLSLAILGSRLA 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  78 LTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNW 157
Cdd:PRK06525  326 LEGSIAYIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLVGVGFCVAALAITGVPPFNGFFSKFPIFAAGFEL 405

                         170
                  ....*....|....
gi 1067529743 158 SNLTITMTGLGTLL 171
Cdd:PRK06525  406 SVEYWILLPAMVLL 419
PRK12646 PRK12646
DUF4040 family protein;
1-217 3.20e-05

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 44.36  E-value: 3.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNpLTTNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLV-----IAACLIQTQ 75
Cdd:PRK12646  249 SATMVKAGIFLLFRFTPLLG-LSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMImamvgIGGGYAQHQ 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  76 ---------WSLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMAnLMNMALPPTIN--I 144
Cdd:PRK12646  328 qdaiasiyvFVLFAALFHLMNHAIFKCALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVMTIA-ALSMAGVPFLNgfL 406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743 145 TGELLI--MASTFNWSN----LTITMTGLG---TLLTATYSLYMFLMTQRGKLPTHITQTEPTHtrEHLLMALHTMPMLL 215
Cdd:PRK12646  407 SKEMFLdaLTQTGQLSQfsliSMIIIVFIGviaSIFTFTYALYMVKEVFWGKYDSKVFTKKNIH--EPWLFSLPSLILMV 484


                  ..
gi 1067529743 216 LM 217
Cdd:PRK12646  485 LV 486
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-181 4.37e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 43.79  E-value: 4.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNplttNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIqtqwsltg 80
Cdd:PRK07234  223 SGVVVKAGVFPLVRCALDVP----GLDLIVRIFGVGTALLGVLFALLEKDLKRMLAFSTISQLGFILAAPLV-------- 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  81 AIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLmttwwLMANLMNMALPPTINITGELLIMASTFNWSNL 160
Cdd:PRK07234  291 GGLYALAHGLVKSTLFLCAGALPSRNFTELISQMLGIGKWIPL-----TMASFSIAGFPLLAGFVSKVLTLKNLLPWQAI 365

                         170       180
                  ....*....|....*....|.
gi 1067529743 161 TITMTGLGTllTATYSLYMFL 181
Cdd:PRK07234  366 ALNLAAVGT--AASFWKFIFL 384
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 4-96 7.57e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.06  E-value: 7.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   4 LLKLGGYG------IIRITPMLNPLTTNM-----YYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLI 72
Cdd:PRK08668  238 LSKLGAYGfllvlyVLPGTKLFSEFGTYRgvplfNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGL 317

                          90       100
                  ....*....|....*....|....
gi 1067529743  73 QTQWSLTGAIVLMVAHGLTSSMLF 96
Cdd:PRK08668  318 GTSLGFAGGLFHVFNHALFKGLFF 341
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 8-172 1.43e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 42.39  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   8 GGYGIIRI-----TPMLNPLTTNmyYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQT-------- 74
Cdd:PRK08376  265 GLYALARVlfsiyGPAINLATVG--WVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLGVGLaalgdpam 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  75 ----QWSLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLI 150
Cdd:PRK08376  343 asygEIALAGGIYHIVNHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422

                         170       180
                  ....*....|....*....|..
gi 1067529743 151 MASTFNWSNLTITMTGLGTLLT 172
Cdd:PRK08376  423 YESSALFNPILGVIAMIGSVLT 444
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 5-162 2.67e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 41.45  E-value: 2.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   5 LKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSticLRQTDLKSLIAYSSVSHMgLVIAACLIQTQWSLTG-AIV 83
Cdd:MTH00062  208 MKLGLLGVYRFCGFIFSGSFLGYLFLCCLFSVFFLITA---CSELDGKRWLAFLSLSHI-LVPVLGLFVGDWSSINlSFF 283

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1067529743  84 LMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSNLTI 162
Cdd:MTH00062  284 YCLGHGLSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTIQFFCEVFLVSSSFGVLVYLL 362
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
1-225 2.87e-04

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 41.47  E-value: 2.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTNMYYPFIMLAMWGIIMTSTI-CLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLT 79
Cdd:PRK12663  245 AALLTKVGIYALIRVFTLLFPQERELLHPLLATMAAITMVIGALgALAYKDIRRIAGYQVISSIGFILLGLALGTPAGIN 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  80 GAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIMASTFNWSN 159
Cdd:PRK12663  325 GAIFYLVHDMVVKTALFLIAGSLVRLTGYRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGA 404

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1067529743 160 LTITMTGLGTLLTATYSLY-MFLMTQRGKLPTHITQTEPTHTREHLLMALHTMPMLLLMLKPQLIMG 225
Cdd:PRK12663  405 YILLALMLITSLITMYSLFrIFFLAYWGDKDGEEVNFKPIPLYRKLPLSILAVVVIAMGIAAEPLLN 471
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
31-179 6.41e-04

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 40.40  E-value: 6.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  31 IMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRT 110
Cdd:PRK06277  270 IALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSN 349

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1067529743 111 LLLARGLQLILPLMTTWWLMANLMNMALPPTINITGELLIM--ASTFNWSNLTITM--TGLGTLLT---ATYSLYM 179
Cdd:PRK06277  350 LRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQSKLMLAqaAMQANMPELAIIMiiVSIGTFVSmmkAFYLIYL 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 2-224 9.45e-04

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 39.55  E-value: 9.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   2 AILLKLGGYGIIRITPmlnplttNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQTQWSLTGA 81
Cdd:TIGR01770 251 AVFLRLFLYILFGFSE-------AWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAV 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  82 IVLMVAHGLTSSMLF-CLANT-NYERTHSRTLLLARGLQLILPLMTTwwLMA-NLMNMA-LPPTINITGELLIMASTFN- 156
Cdd:TIGR01770 324 LFYIFIYALMSLGAFgVLSLLrSYKDEWIEYISDFAGLFKTNPILAI--LILiFMFSLAgIPPLAGFFGKFYVFFALLKs 401

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1067529743 157 ----WSNLTITMTGLGTLLTATYSLYMFLMTQRGKLPTHitqtePTHTREHLLMALHTMPMLLLMLKPQLIM 224
Cdd:TIGR01770 402 glywLAVIAVLTSVIGAFYYLRVVKVMYFDKPERRIPSN-----PQSKAQSLLLSISALFILFLGLFPSLIL 468
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-178 1.46e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 39.18  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743   1 AAILLKLGGYGIIRITPMLNPLTTnmyypFIMLAMWGIIMTSTI----CLRQTDLKSLIAYSSVSHMGLVIAACLIQTQW 76
Cdd:PRK12665  248 AGLLTKVGVYAIIRTHTLLFPGGG-----LDTLLMVVALLTMVVgilgAIAQSDIKRLLSFTLVSHIGYMVFGIALSTVA 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  77 SLTGAIVLMVAHGLTSSMLFCLANTNYERTHSRTLLLARGLQLILPLMTTWWLMANlMNMA-LPPTINITGEL-LIMAST 154
Cdd:PRK12665  323 GLSGAIYYVAHHITVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVLFFVPA-LNLGgIPPFSGFIGKVaLLEAGA 401

                         170       180
                  ....*....|....*....|....
gi 1067529743 155 FNWSNLTITMTGlGTLLTATYSLY 178
Cdd:PRK12665  402 EDGTWLAWALVA-GGVVTSLLTLY 424
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 17-182 8.51e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 36.79  E-value: 8.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  17 PMLNPLTtNMYYPFIMLAMWGIIMTSTICLRQTDLKSLIAYSSVSHMGLVIAACLIQtqwSLTGAIVLMVAHGLTSSMLF 96
Cdd:MTH00144  135 SNFLDLY-WLAYLLCVISVLSALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHG---SWLMWMYFLIYIVSSGFLFF 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1067529743  97 CLANTNyerthsrTLLLARGLQLILPLMTTWWLMANLMNMA-LPPTINITGELLIMASTFNWSNLTITMTG-LGTLLTAT 174
Cdd:MTH00144  211 SLWSGD-------SGSMKDLGSLKPSYKTGLSIISLLLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLlLGSLISLF 283


                  ....*...
gi 1067529743 175 YSLYMFLM 182
Cdd:MTH00144  284 FYLSVFFS 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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