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Conserved domains on  [gi|1062071335|gb|AOL21131|]
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peptidase S9 [Xanthomonas citri pv. malvacearum]

Protein Classification

S9 family peptidase( domain architecture ID 12012107)

peptidase S9 family protein, an oligopeptidase which may cleave the prolyl bond of short peptides, similar to oligopeptidase B, which cleaves on the C-terminal side of lysyl and argininyl residues

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 117-451 2.72e-117

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 357.01  E-value: 2.72e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 117 APDAHALLF----------PLGGELYLYDLRKtgaAAIRKLTHGEGFATDAKLSPKGGFVSFVRERNLWVIELASGNALQ 186
Cdd:pfam00930   1 SPDGKYLLLatnytknwrhSYTADYYIYDLET---NRVEPLPPGEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 187 LTQDGSETIGNGVAEFVADEE-MDRHTGYWWAPDDSAIAFARIDEALVPVQKRPEVYADHT--EVISQRYPQAGQPNVAV 263
Cdd:pfam00930  78 ITSDGSDGIFNGVADWVYEEEvLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDEGPgpEVREIKYPKAGAPNPTV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 264 QLGVIAPRAKATPRW--IDLGKNPDIYLARVDWRDAQRLTFQRQSRDQKTLELIETTLASGAQRTLITETSPTWVPLHND 341
Cdd:pfam00930 158 ELFVYDLASGKTVEVvpPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQD 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 342 LRFLK--DGRFLWNSERSGYAHLYLASDDGRTLTPLTSGNWVVDALLAVDEQAGTVYFAASKDGPTQTHLYAVPLA-GGA 418
Cdd:pfam00930 238 PHFIKrdGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDsGGE 317

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1062071335 419 IEKRSATNGTH--AASFANNASVYVDTWSNTTTPP 451
Cdd:pfam00930 318 PTCLTDDSGDHdySASFSPNGSYYVLTYSGPDTPP 352
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
492-741 5.72e-71

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


:

Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 231.44  E-value: 5.72e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 492 TLTAADGkTPLHYRLTKPEhfdPAKRYPVIVYVYGGPAAQtvldawpSRGDALFDQYLAQRGYVVFSLDNRGTPRRGREF 571
Cdd:COG1506     1 TFKSADG-TTLPGWLYLPA---DGKKYPVVVYVHGGPGSR-------DDSFLPLAQALASRGYAVLAPDYRGYGESAGDW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 572 GGalygrqgtVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDWGLYDT---HYT 648
Cdd:COG1506    70 GG--------DEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGttrEYT 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 649 ERYMDLPARNAAGYRDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQRGTPFELMTYPGAKHGLSGATALHR 728
Cdd:COG1506   142 ERLMGGPWEDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAGAPDY 221

                         250
                  ....*....|...
gi 1062071335 729 YKTAEAFIERCLG 741
Cdd:COG1506   222 LERILDFLDRHLK 234
COG4946 super family cl27624
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 31-173 6.78e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


The actual alignment was detected with superfamily member COG4946:

Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 40.02  E-value: 6.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335   31 PLPLSGPTL-MKPKVAPDGSRVTFlrgkdsDRNQLDLWEFDIASGQTRLLVDSKVvlpgtevlsdvekarrerqriaaFT 109
Cdd:COG4946    382 QLTLGDLGRvFNPVWSPDGKKIAF------TDNRGRLWVVDLASGKVRKVDTDGY-----------------------GD 432

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1062071335  110 GIVDYQWAPDAHALLFPLGG-----ELYLYDLRKTgaaAIRKLTHGEGFATDAKLSPKGGFVSFVRERN 173
Cdd:COG4946    433 GISDLAWSPDSKWLAYSKPGpnqlsQIFLYDVETG---KTVQLTDGRYDDGSPAFSPDGKYLYFLSSRD 498
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 117-451 2.72e-117

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 357.01  E-value: 2.72e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 117 APDAHALLF----------PLGGELYLYDLRKtgaAAIRKLTHGEGFATDAKLSPKGGFVSFVRERNLWVIELASGNALQ 186
Cdd:pfam00930   1 SPDGKYLLLatnytknwrhSYTADYYIYDLET---NRVEPLPPGEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 187 LTQDGSETIGNGVAEFVADEE-MDRHTGYWWAPDDSAIAFARIDEALVPVQKRPEVYADHT--EVISQRYPQAGQPNVAV 263
Cdd:pfam00930  78 ITSDGSDGIFNGVADWVYEEEvLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDEGPgpEVREIKYPKAGAPNPTV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 264 QLGVIAPRAKATPRW--IDLGKNPDIYLARVDWRDAQRLTFQRQSRDQKTLELIETTLASGAQRTLITETSPTWVPLHND 341
Cdd:pfam00930 158 ELFVYDLASGKTVEVvpPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQD 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 342 LRFLK--DGRFLWNSERSGYAHLYLASDDGRTLTPLTSGNWVVDALLAVDEQAGTVYFAASKDGPTQTHLYAVPLA-GGA 418
Cdd:pfam00930 238 PHFIKrdGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDsGGE 317

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1062071335 419 IEKRSATNGTH--AASFANNASVYVDTWSNTTTPP 451
Cdd:pfam00930 318 PTCLTDDSGDHdySASFSPNGSYYVLTYSGPDTPP 352
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
492-741 5.72e-71

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 231.44  E-value: 5.72e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 492 TLTAADGkTPLHYRLTKPEhfdPAKRYPVIVYVYGGPAAQtvldawpSRGDALFDQYLAQRGYVVFSLDNRGTPRRGREF 571
Cdd:COG1506     1 TFKSADG-TTLPGWLYLPA---DGKKYPVVVYVHGGPGSR-------DDSFLPLAQALASRGYAVLAPDYRGYGESAGDW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 572 GGalygrqgtVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDWGLYDT---HYT 648
Cdd:COG1506    70 GG--------DEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGttrEYT 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 649 ERYMDLPARNAAGYRDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQRGTPFELMTYPGAKHGLSGATALHR 728
Cdd:COG1506   142 ERLMGGPWEDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAGAPDY 221

                         250
                  ....*....|...
gi 1062071335 729 YKTAEAFIERCLG 741
Cdd:COG1506   222 LERILDFLDRHLK 234
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
547-743 2.60e-62

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 207.85  E-value: 2.60e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 547 QYLAQRGYVVFSLDNRGTPRRGREFGGALYGRQGTVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSD 626
Cdd:pfam00326   8 QLLADRGYVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRPD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 627 AYACGVAGAPVTDWGLYDTH----YTERYMDLPA--RNAAGYRDARIATHLDGLRAK--LLLIHGMADDNVLFTNSTALM 698
Cdd:pfam00326  88 LFKAAVAHVPVVDWLAYMSDtslpFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYppLLLIHGLLDDRVPPWQSLKLV 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1062071335 699 SALQQRGTPFELMTYPGAKHG-LSGATALHRYKTAEAFIERCLGSS 743
Cdd:pfam00326 168 AALQRKGVPFLLLIFPDEGHGiGKPRNKVEEYARELAFLLEYLGGT 213
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 282-462 2.01e-08

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 53.91  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 282 GKNPDIYLARVDWRDAQRLTfqrqsrdqktleliettlasgaqRTLITETSPTWVPlhndlrflkDGRFL-WNSERSGYA 360
Cdd:COG0823     8 DGNSDIYVVDLDGGEPRRLT-----------------------NSPGIDTSPAWSP---------DGRRIaFTSDRGGGP 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 361 HLYLASDDGRTLTPLT-SGNWVVDALLAVDEQagTVYFAASKDGptQTHLYAVPLAGGAIekRSATNGTHAASFANNAS- 438
Cdd:COG0823    56 QIYVVDADGGEPRRLTfGGGYNASPSWSPDGK--RLAFVSRSDG--RFDIYVLDLDGGAP--RRLTDGPGSPSWSPDGRr 129

                         170       180
                  ....*....|....*....|....*
gi 1062071335 439 -VYVdtwSNTTTPPQIELFRASGEK 462
Cdd:COG0823   130 iVFS---SDRGGRPDLYVVDLDGRK 151
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 31-173 6.78e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 40.02  E-value: 6.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335   31 PLPLSGPTL-MKPKVAPDGSRVTFlrgkdsDRNQLDLWEFDIASGQTRLLVDSKVvlpgtevlsdvekarrerqriaaFT 109
Cdd:COG4946    382 QLTLGDLGRvFNPVWSPDGKKIAF------TDNRGRLWVVDLASGKVRKVDTDGY-----------------------GD 432

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1062071335  110 GIVDYQWAPDAHALLFPLGG-----ELYLYDLRKTgaaAIRKLTHGEGFATDAKLSPKGGFVSFVRERN 173
Cdd:COG4946    433 GISDLAWSPDSKWLAYSKPGpnqlsQIFLYDVETG---KTVQLTDGRYDDGSPAFSPDGKYLYFLSSRD 498
 
Name Accession Description Interval E-value
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 117-451 2.72e-117

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 357.01  E-value: 2.72e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 117 APDAHALLF----------PLGGELYLYDLRKtgaAAIRKLTHGEGFATDAKLSPKGGFVSFVRERNLWVIELASGNALQ 186
Cdd:pfam00930   1 SPDGKYLLLatnytknwrhSYTADYYIYDLET---NRVEPLPPGEGKIQDAKWSPDGDRLAFVRDNNLYVRELATGKEIQ 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 187 LTQDGSETIGNGVAEFVADEE-MDRHTGYWWAPDDSAIAFARIDEALVPVQKRPEVYADHT--EVISQRYPQAGQPNVAV 263
Cdd:pfam00930  78 ITSDGSDGIFNGVADWVYEEEvLGSNSAVWWSPDGSRLAFLRFDESEVPIITLPYYTDEGPgpEVREIKYPKAGAPNPTV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 264 QLGVIAPRAKATPRW--IDLGKNPDIYLARVDWRDAQRLTFQRQSRDQKTLELIETTLASGAQRTLITETSPTWVPLHND 341
Cdd:pfam00930 158 ELFVYDLASGKTVEVvpPDDLSDADYYITRVKWVPDGKLLVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQD 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 342 LRFLK--DGRFLWNSERSGYAHLYLASDDGRTLTPLTSGNWVVDALLAVDEQAGTVYFAASKDGPTQTHLYAVPLA-GGA 418
Cdd:pfam00930 238 PHFIKrdGSGFLWISERDGYNHLYLYDLDGKSPIQLTSGNWEVTSILGVDETRDLVYFTATEDSPTERHLYSVSLDsGGE 317

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1062071335 419 IEKRSATNGTH--AASFANNASVYVDTWSNTTTPP 451
Cdd:pfam00930 318 PTCLTDDSGDHdySASFSPNGSYYVLTYSGPDTPP 352
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
492-741 5.72e-71

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 231.44  E-value: 5.72e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 492 TLTAADGkTPLHYRLTKPEhfdPAKRYPVIVYVYGGPAAQtvldawpSRGDALFDQYLAQRGYVVFSLDNRGTPRRGREF 571
Cdd:COG1506     1 TFKSADG-TTLPGWLYLPA---DGKKYPVVVYVHGGPGSR-------DDSFLPLAQALASRGYAVLAPDYRGYGESAGDW 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 572 GGalygrqgtVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDWGLYDT---HYT 648
Cdd:COG1506    70 GG--------DEVDDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGttrEYT 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 649 ERYMDLPARNAAGYRDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQRGTPFELMTYPGAKHGLSGATALHR 728
Cdd:COG1506   142 ERLMGGPWEDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAGAPDY 221

                         250
                  ....*....|...
gi 1062071335 729 YKTAEAFIERCLG 741
Cdd:COG1506   222 LERILDFLDRHLK 234
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
547-743 2.60e-62

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 207.85  E-value: 2.60e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 547 QYLAQRGYVVFSLDNRGTPRRGREFGGALYGRQGTVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSD 626
Cdd:pfam00326   8 QLLADRGYVVAIANGRGSGGYGEAFHDAGKGDLGQNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRPD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 627 AYACGVAGAPVTDWGLYDTH----YTERYMDLPA--RNAAGYRDARIATHLDGLRAK--LLLIHGMADDNVLFTNSTALM 698
Cdd:pfam00326  88 LFKAAVAHVPVVDWLAYMSDtslpFTERYMEWGNpwDNEEGYDYLSPYSPADNVKVYppLLLIHGLLDDRVPPWQSLKLV 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1062071335 699 SALQQRGTPFELMTYPGAKHG-LSGATALHRYKTAEAFIERCLGSS 743
Cdd:pfam00326 168 AALQRKGVPFLLLIFPDEGHGiGKPRNKVEEYARELAFLLEYLGGT 213
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
492-719 8.34e-20

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 88.87  E-value: 8.34e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 492 TLTAADGkTPLHYRLTKPEHfdpAKRYPVIVyvyggpaaqtVLDAWPSRGDALFD--QYLAQRGYVVFSLD--NRGTPRR 567
Cdd:COG0412     7 TIPTPDG-VTLPGYLARPAG---GGPRPGVV----------VLHEIFGLNPHIRDvaRRLAAAGYVVLAPDlyGRGGPGD 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 568 GREFGGALYGRQGTVEVDDQLQG-VAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSDAyACGVA--GAPVTDWGLyd 644
Cdd:COG0412    73 DPDEARALMGALDPELLAADLRAaLDWLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPDL-AAAVSfyGGLPADDLL-- 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1062071335 645 thyterymDLPARnaagyrdariathldgLRAKLLLIHGMADDNVLFTNSTALMSALQQRGTPFELMTYPGAKHG 719
Cdd:COG0412   150 --------DLAAR----------------IKAPVLLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYPGAGHG 200
COG4099 COG4099
Predicted peptidase [General function prediction only];
484-719 2.25e-17

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 81.94  E-value: 2.25e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 484 AQPPIAFGTLTAADGKTPLHYRLTKPEHFDPAKRYPVIVYVYG----GPAAQTVLDAWPSRgdALFDQYLAQRGYVVFSl 559
Cdd:COG4099    15 AQDGFEARTFTDPSDGDTLPYRLYLPKGYDPGKKYPLVLFLHGagerGTDNEKQLTHGAPK--FINPENQAKFPAIVLA- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 560 dnrgtP--RRGREFggalygrQGTVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSDAYAcgvAGAPV 637
Cdd:COG4099    92 -----PqcPEDDYW-------SDTKALDAVLALLDDLIAEYRIDPDRIYLTGLSMGGYGTWDLAARYPDLFA---AAVPI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 638 TDWGlyDTHYTERYMDLParnaagyrdariathldglrakLLLIHGMADDNVLFTNSTALMSALQQRGTPFELMTYPGAK 717
Cdd:COG4099   157 CGGG--DPANAANLKKVP----------------------VWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVG 212


                  ..
gi 1062071335 718 HG 719
Cdd:COG4099   213 HN 214
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 492-718 4.07e-15

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 75.72  E-value: 4.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 492 TLTAADGkTPLHYRLTKPEhfDPAKRYPVIVYV--YGGPAAQTVLDAwpsrgdalfdQYLAQRGYVVFSLDNRGTprrgr 569
Cdd:COG1073    14 TFKSRDG-IKLAGDLYLPA--GASKKYPAVVVAhgNGGVKEQRALYA----------QRLAELGFNVLAFDYRGY----- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 570 efgGALYGR---QGTVEVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLA--KRSDAYA--CGVAGAPVTDWGL 642
Cdd:COG1073    76 ---GESEGEpreEGSPERRDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAAtdPRVKAVIldSPFTSLEDLAAQR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 643 YDTHYTERYMDLPARNAAGY-----RDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQrgtPFELMTYPGAK 717
Cdd:COG1073   153 AKEARGAYLPGVPYLPNVRLasllnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAE---PKELLIVPGAG 229


                  .
gi 1062071335 718 H 718
Cdd:COG1073   230 H 230
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
513-741 4.08e-13

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 68.75  E-value: 4.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 513 DPAKRYPVIVYVYGGpaaqtvldAW----PSRGDALFDQYLAQRGYVVFSLDNRGTPRRGreFGGALygrqgtvevDDQL 588
Cdd:COG0657     8 GAKGPLPVVVYFHGG--------GWvsgsKDTHDPLARRLAARAGAAVVSVDYRLAPEHP--FPAAL---------EDAY 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 589 QGVAWLRQQS---WVDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGApVTDWGLYDTHYTerymdlPARNaagyrda 665
Cdd:COG0657    69 AALRWLRANAaelGIDPDRIAVAGDSAGGHLAAALALRARDRGGPRPAAQ-VLIYPVLDLTAS------PLRA------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 666 riatHLDGLrAKLLLIHGMADdnVLFTNSTALMSALQQRGTPFELMTYPGAKHGLSGATALHR----YKTAEAFIERCLG 741
Cdd:COG0657   135 ----DLAGL-PPTLIVTGEAD--PLVDESEALAAALRAAGVPVELHVYPGGGHGFGLLAGLPEaraaLAEIAAFLRRALA 207
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
490-738 2.57e-12

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 66.95  E-value: 2.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 490 FGTLTAADGKTpLHYRLTKPEhfDPAKryPVIVYVYGGpaaqtvldaWPSRGD-ALFDQYLAQRGYVVFSLDNRGTPRRG 568
Cdd:COG2267     5 LVTLPTRDGLR-LRGRRWRPA--GSPR--GTVVLVHGL---------GEHSGRyAELAEALAAAGYAVLAFDLRGHGRSD 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 569 REfggalYGRQGTVE--VDDQLQGVAWLRQQswvDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPvtdwglydth 646
Cdd:COG2267    71 GP-----RGHVDSFDdyVDDLRAALDALRAR---PGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAP---------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 647 yteRYMDLPAR--NAAGYRDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQRGTpfeLMTYPGAKHGLSGAT 724
Cdd:COG2267   133 ---AYRADPLLgpSARWLRALRLAEALARIDVPVLVLHGGADRVVPPEAARRLAARLSPDVE---LVLLPGARHELLNEP 206

                         250
                  ....*....|....*
gi 1062071335 725 ALHR-YKTAEAFIER 738
Cdd:COG2267   207 AREEvLAAILAWLER 221
Axe1 COG3458
Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, ...
 498-622 8.11e-09

Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442681 [Multi-domain]  Cd Length: 318  Bit Score: 57.89  E-value: 8.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 498 GKTPLHYRLTKPEHfdpAKRYPVIVYV--YGGpaaqtvldawpSRGDALFDQYLAQRGYVVFSLDNRG-------TPRRG 568
Cdd:COG3458    65 GGARIYGWLLRPKG---EGPLPAVVEFhgYGG-----------GRGLPHEDLDWAAAGYAVLVMDTRGqgsswgdTPDPG 130

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1062071335 569 REFGGALYGRQ------------GTVeVDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLA 622
Cdd:COG3458   131 GYSGGALPGYMtrgiddpdtyyyRRV-YLDAVRAVDALRSLPEVDGKRIGVTGGSQGGGLALAAAA 195
COG2936 COG2936
Predicted acyl esterase [General function prediction only];
494-640 1.68e-08

Predicted acyl esterase [General function prediction only];


Pssm-ID: 442179 [Multi-domain]  Cd Length: 555  Bit Score: 57.63  E-value: 1.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 494 TAADGKTpLHYRLTKPEhfDPAKRYPVIVY--VYGGPAAQTVLDAWPSRgdalfdqYLAQRGYVVFSLDNRGTPRRGREF 571
Cdd:COG2936    18 PMRDGVR-LAADIYRPK--DAEGPVPVILErtPYGKRDGTAGRDLGPHP-------YFAERGYAVVVQDVRGTGGSEGEF 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1062071335 572 ggALYGRQgtvEVDDQLQGVAWLRQQSWVDAKrIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDW 640
Cdd:COG2936    88 --DPYRVD---EQTDGYDTIDWLAKQPWSNGK-VGMIGISYGGFTQLAAAADRPPALKAIVPQAPTSDR 150
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 282-462 2.01e-08

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 53.91  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 282 GKNPDIYLARVDWRDAQRLTfqrqsrdqktleliettlasgaqRTLITETSPTWVPlhndlrflkDGRFL-WNSERSGYA 360
Cdd:COG0823     8 DGNSDIYVVDLDGGEPRRLT-----------------------NSPGIDTSPAWSP---------DGRRIaFTSDRGGGP 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 361 HLYLASDDGRTLTPLT-SGNWVVDALLAVDEQagTVYFAASKDGptQTHLYAVPLAGGAIekRSATNGTHAASFANNAS- 438
Cdd:COG0823    56 QIYVVDADGGEPRRLTfGGGYNASPSWSPDGK--RLAFVSRSDG--RFDIYVLDLDGGAP--RRLTDGPGSPSWSPDGRr 129

                         170       180
                  ....*....|....*....|....*
gi 1062071335 439 -VYVdtwSNTTTPPQIELFRASGEK 462
Cdd:COG0823   130 iVFS---SDRGGRPDLYVVDLDGRK 151
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 491-735 8.44e-08

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 54.24  E-value: 8.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 491 GTLTAADGKtpLHYRLTKPEHFDPAKRYPVIVYV--YGGPAAQTvldawpsRGDALFDQYLAQRGYVVFSLD-NRGTPRR 567
Cdd:COG3509    28 RTFTVGGGT--RTYRLYVPAGYDGGAPLPLVVALhgCGGSAADF-------AAGTGLNALADREGFIVVYPEgTGRAPGR 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 568 GREFGGALYGRQGTVEVD--DQLqgVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLLAKRSDAYAcgvAGAPVtdwglydt 645
Cdd:COG3509    99 CWNWFDGRDQRRGRDDVAfiAAL--VDDLAARYGIDPKRVYVTGLSAGGAMAYRLACEYPDVFA---AVAPV-------- 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 646 hyterymdlparnaAG--YRDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQR------------------- 704
Cdd:COG3509   166 --------------AGlpYGAASDAACAPGRPVPVLVIHGTADPTVPYAGAEETLAQWAALngcaatptrtevtdgggyt 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1062071335 705 ---------GTPFELMTYPGAKHGLSGATALHRYKTAEAF 735
Cdd:COG3509   232 rtrysdcagGAEVELYTVEGGGHAWPGGGAAGPYTDPRGI 271
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 130-227 3.82e-07

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 50.44  E-value: 3.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 130 ELYLYDLRkTGAaaIRKLTHGEGFATDAKLSPKGGFVSFVRER----NLWVIELASGNALQLTQDGSetigngvaefvad 205
Cdd:COG0823    12 DIYVVDLD-GGE--PRRLTNSPGIDTSPAWSPDGRRIAFTSDRgggpQIYVVDADGGEPRRLTFGGG------------- 75

                          90       100
                  ....*....|....*....|..
gi 1062071335 206 eemdRHTGYWWAPDDSAIAFAR 227
Cdd:COG0823    76 ----YNASPSWSPDGKRLAFVS 93
Peptidase_S15 pfam02129
X-Pro dipeptidyl-peptidase (S15 family);
546-710 9.81e-07

X-Pro dipeptidyl-peptidase (S15 family);


Pssm-ID: 396621 [Multi-domain]  Cd Length: 264  Bit Score: 50.80  E-value: 9.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 546 DQYLAQRGYVVFSLDNRGTPRRGREFGGALYGrqgtvEVDDQLQGVAWLRQQSWvDAKRIGVQGWSNGGYMTLMLLAKRS 625
Cdd:pfam02129  44 EWEFAARGYAVVYQDVRGTGGSEGVFTVGGPQ-----EAADGKDVIDWLAGQPW-CNGKVGMTGISYLGTTQLAAAATGP 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 626 DAYACGVAGAPVTDWglYDTHY---------------------------------------------------------T 648
Cdd:pfam02129 118 PGLKAIAPESGISDL--YDYYReggavrapgglgwedldllaealtsrraddgdayraaaryeaagdellaeldrqlflL 195

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1062071335 649 ERYMDLPARNAAgYRDARIATHLDGLRAKLLLIHGMADDNVLfTNSTALMSALQQRGTPFEL 710
Cdd:pfam02129 196 EWLLQTGDYDAF-WQDRNYLEDADKVKAPVLLVGGWQDWNVK-NGAIKLYEALRAPGVKKKL 255
COG2945 COG2945
Alpha/beta superfamily hydrolase [General function prediction only];
549-722 1.00e-06

Alpha/beta superfamily hydrolase [General function prediction only];


Pssm-ID: 442188 [Multi-domain]  Cd Length: 201  Bit Score: 50.16  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 549 LAQRGYVVFSLDNRGTprrGR---EFGgalygrQGTVEVDDQLQGVAWLRQQSwvdAKRIGVQGWSNGGYMTLMLLAKRS 625
Cdd:COG2945    51 LVAAGFAVLRFNFRGV---GRsegEFD------EGRGELDDAAAALDWLRAQN---PLPLWLAGFSFGAYVALQLAMRLP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 626 DAYACGVAGAPVtdwGLYDthyterymdlparnaagyrdariATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALQQrg 705
Cdd:COG2945   119 EVEGLILVAPPV---NRYD-----------------------FSFLAPCPAPTLVIHGEQDEVVPPAEVLDWARPLSP-- 170

                         170
                  ....*....|....*..
gi 1062071335 706 tPFELMTYPGAKHGLSG 722
Cdd:COG2945   171 -PLPVVVVPGADHFFHG 186
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 115-229 1.09e-06

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 52.35  E-value: 1.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335  115 QWAPDAHALLFPL--GGE--LYLYDLrkTGAAAIRKLTHGE-GFATDAKLSPKGGFVSFVRERN-LWVIELASGNALQLT 188
Cdd:COG4946    349 AWSPDGKSIAYFSdaSGEyeLYIAPA--DGSGEPKQLTLGDlGRVFNPVWSPDGKKIAFTDNRGrLWVVDLASGKVRKVD 426

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1062071335  189 QDGSETIGNGVAefvadeemdrhtgywWAPDDSAIAFARID 229
Cdd:COG4946    427 TDGYGDGISDLA---------------WSPDSKWLAYSKPG 452
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 59-227 1.53e-06

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 48.51  E-value: 1.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335  59 SDRN-QLDLWEFDIASGQTRLLVDSkvvlPGTEVlsdvekarrerqriaaftgivDYQWAPDAHALLF----PLGGELYL 133
Cdd:COG0823     5 LSRDgNSDIYVVDLDGGEPRRLTNS----PGIDT---------------------SPAWSPDGRRIAFtsdrGGGPQIYV 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 134 YDLRkTGAAaiRKLTHGEGFATDAKLSPKGGFVSFVRERN----LWVIELASGNALQLTQDGSEtigngvaefvadeemd 209
Cdd:COG0823    60 VDAD-GGEP--RRLTFGGGYNASPSWSPDGKRLAFVSRSDgrfdIYVLDLDGGAPRRLTDGPGS---------------- 120

                         170
                  ....*....|....*...
gi 1062071335 210 rhtgYWWAPDDSAIAFAR 227
Cdd:COG0823   121 ----PSWSPDGRRIVFSS 134
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
509-716 1.75e-06

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 50.62  E-value: 1.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 509 PEHFDPAKRYPVIVYVYGGPAAQtvlDAWPSRGDA--LFDQYLAQ---RGYVVFSLDNRGTPRRGRE-FGGALYGRqgtv 582
Cdd:COG2382   103 PGYDNPGKKYPVLYLLDGGGGDE---QDWFDQGRLptILDNLIAAgkiPPMIVVMPDGGDGGDRGTEgPGNDAFER---- 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 583 EVDDQLqgVAWLRQQ--SWVDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDWGlydthyterymdlPARNAA 660
Cdd:COG2382   176 FLAEEL--IPFVEKNyrVSADPEHRAIAGLSMGGLAALYAALRHPDLFGYVGSFSGSFWWP-------------PGDADR 240

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1062071335 661 GYRDARIATHLDGLRAKLLLIHGMADDnvLFTNSTALMSALQQRGTPFELMTYPGA 716
Cdd:COG2382   241 GGWAELLAAGAPKKPLRFYLDVGTEDD--LLEANRALAAALKAKGYDVEYREFPGG 294
BD-FAE pfam20434
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, ...
 514-701 2.02e-06

BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, previously known as bifunctional carbohydrate esterase (CE)), which is active on complex natural xylans and was identified as the basis of a monophyletic clade gathering all homologs identified in PULs (polysaccharide utilization loci) predicted to act on xylan. It adopts an alpha-beta-hydrolase fold with the catalytic triad Ser-Asp-His. This new family of proteins is a new candidate for biomass processing due to its capacity to remove ferulic acid and acetic acid from natural corn and birchwood xylan substrates.


Pssm-ID: 466583 [Multi-domain]  Cd Length: 215  Bit Score: 49.49  E-value: 2.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 514 PAKR---YPVIVYVYGGpaaqtvldAW---PSRGDALFDQY----LAQRGYVVFSLDNRGTprrgrefGGALYGRQgtve 583
Cdd:pfam20434   6 PKNAkgpYPVVIWIHGG--------GWnsgDKEADMGFMTNtvkaLLKAGYAVASINYRLS-------TDAKFPAQ---- 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 584 VDDQLQGVAWLRQQSW---VDAKRIGVQGWSNGGYMTLML----------------LAKRSD-----AYACGVAG-APVT 638
Cdd:pfam20434  67 IQDVKAAIRFLRANAAkygIDTNKIALMGFSAGGHLALLAglsnnnkefegnvgdyTPESSKesfkvNAVVDFYGpTDLL 146

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1062071335 639 DWGLYDTHYTERYM------DLPARNAAGYRDARIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSAL 701
Cdd:pfam20434 147 DMDSCGTHNDAKSPetlllgAPPLENPDLAKSASPITYVDKNDPPFLIIHGDKDPLVPYCQSVLLHEKL 215
YpfH COG0400
Predicted esterase [General function prediction only];
547-723 5.30e-06

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 47.98  E-value: 5.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 547 QYLAQRGYVVFSLD-NRGTPRRGR-----EFGGALYGRQGTVEVDDQLQG-VAWLRQQSWVDAKRIGVQGWSNGGYMTLM 619
Cdd:COG0400    26 PELALPGAAVLAPRaPVPEGPGGRawfdlSFLEGREDEEGLAAAAEALAAfIDELEARYGIDPERIVLAGFSQGAAMALS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 620 LLAKRSDAYACGVA--GAPVTDwglydthyterymDLPARNAAGYRDARIathldglraklLLIHGMADDNVLFTNSTAL 697
Cdd:COG0400   106 LALRRPELLAGVVAlsGYLPGE-------------EALPAPEAALAGTPV-----------FLAHGTQDPVIPVERAREA 161

                         170       180
                  ....*....|....*....|....*.
gi 1062071335 698 MSALQQRGTPFELMTYPGAkHGLSGA 723
Cdd:COG0400   162 AEALEAAGADVTYREYPGG-HEISPE 186
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
492-718 5.47e-05

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 45.87  E-value: 5.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 492 TLTAADGKTPLHYRLTKPEHFDP----AKRYPVIVYVYGGPAAQTVLDAWpsrgdAlfdQYLAQRGYVVFSLDNRGTPRR 567
Cdd:COG4188    32 TLRDPSRDRPLPVDVWYPATAPAdapaGGPFPLVVLSHGLGGSREGYAYL-----A---EHLASHGYVVAAPDHPGSNAA 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 568 GREFGGALYGRQGTVE-----------VDDQLQGvawLRQQSW-----VDAKRIGVQGWSNGGYMTLMLLAKRSD----A 627
Cdd:COG4188   104 DLSAALDGLADALDPEelwerpldlsfVLDQLLA---LNKSDPplagrLDLDRIGVIGHSLGGYTALALAGARLDfaalR 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 628 YACGVAGAPVTDWGlydthyterymdLPARNAAGYRDARI---------------ATHLDGLRAKLLLIHGMADDNVLF- 691
Cdd:COG4188   181 QYCGKNPDLQCRAL------------DLPRLAYDLRDPRIkavvalapggsglfgEEGLAAITIPVLLVAGSADDVTPAp 248

                         250       260
                  ....*....|....*....|....*..
gi 1062071335 692 TNSTALMSALQqrGTPFELMTYPGAKH 718
Cdd:COG4188   249 DEQIRPFDLLP--GADKYLLTLEGATH 273
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
547-738 8.27e-05

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 44.93  E-value: 8.27e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 547 QYLAQRGYVVFSLDNRGTPRRGREFggalygRQGTVE--VDDQLQGVAWLRQQSwvdaKRIGVQGWSNGGYMTLMLLAKR 624
Cdd:COG1647    36 EALAKAGYTVYAPRLPGHGTSPEDL------LKTTWEdwLEDVEEAYEILKAGY----DKVIVIGLSMGGLLALLLAARY 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 625 SDAYACGVAGAPV---------TDWGLYDTHYTERY---MDLPARNAAGYRDARIAT-------------HLDGLRAKLL 679
Cdd:COG1647   106 PDVAGLVLLSPALkiddpsaplLPLLKYLARSLRGIgsdIEDPEVAEYAYDRTPLRAlaelqrlirevrrDLPKITAPTL 185

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 680 LIHGMADDNVLFTNSTALMSALqqRGTPFELMTYPGAKHGLSGATALHR-YKTAEAFIER 738
Cdd:COG1647   186 IIQSRKDEVVPPESARYIYERL--GSPDKELVWLEDSGHVITLDKDREEvAEEILDFLER 243
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 168-417 4.74e-04

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 41.20  E-value: 4.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 168 FVRERN----LWVIELASGNALQLTQDGSEtigngvaefvadeemdrHTGYWWAPDDSAIAFARidealvpvqkrpevya 243
Cdd:COG0823     3 FTLSRDgnsdIYVVDLDGGEPRRLTNSPGI-----------------DTSPAWSPDGRRIAFTS---------------- 49

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 244 dhtevisqrypqagqpnvavqlgviaprakatprwiDLGKNPDIYLARVDWRDAQRLTFQRQSrdqktleliettlasga 323
Cdd:COG0823    50 ------------------------------------DRGGGPQIYVVDADGGEPRRLTFGGGY----------------- 76

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 324 qrtlitETSPTWVPlhndlrflkDGRFL-WNSERSGYAHLYLASDDGRTLTPLTSGNWVVDalLAVDEQagTVYFAASKD 402
Cdd:COG0823    77 ------NASPSWSP---------DGKRLaFVSRSDGRFDIYVLDLDGGAPRRLTDGPGSPS--WSPDGR--RIVFSSDRG 137

                         250
                  ....*....|....*
gi 1062071335 403 GPTQthLYAVPLAGG 417
Cdd:COG0823   138 GRPD--LYVVDLDGR 150
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
601-738 1.15e-03

S-formylglutathione hydrolase FrmB [Defense mechanisms];


Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 41.36  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 601 DAKRIGVQGWSNGGYMTLMLLAKRSDAY--ACGVAGAPVTDWGLYDTHYTERYMDLParNAAGYRDARIATHLDGLRAKL 678
Cdd:COG0627   111 DRERRAIAGLSMGGHGALTLALRHPDLFraVAAFSGILDPSQPPWGEKAFDAYFGPP--DRAAWAANDPLALAEKLRAGL 188

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1062071335 679 -LLIHGMADDNVLFTNSTALMSALQQRGTPFELMTYPGAkhglsgatalHRYKTAEAFIER 738
Cdd:COG0627   189 pLYIDCGTADPFFLEANRQLHAALRAAGIPHTYRERPGG----------HSWYYWASFLED 239
DLH pfam01738
Dienelactone hydrolase family;
549-719 1.33e-03

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 40.80  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 549 LAQRGYVVFSLD---NRGTPRRGREFGGALYGR--QGTVE--VDDQLQGVAWLRQQSWVDAKRIGVQGWSNGGYMTLMLL 621
Cdd:pfam01738  35 LADEGYVALAPDlyfRQGDPNDEADAARAMFELvsKRVMEkvLDDLEAAVNYLKSQPEVSPKKVGVVGYCMGGALAVLLA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 622 AKrsDAYACGVAGApvtdwglydthyterYMDLPARNAAgyRDARIAthldglrAKLLLIHGMADDNVLFTNSTALMSAL 701
Cdd:pfam01738 115 AK--GPLVDAAVGF---------------YGVGPEPPLI--EAPDIK-------APILFHFGEEDHFVPADSRELIEEAL 168

                         170
                  ....*....|....*...
gi 1062071335 702 QQRGTPFELMTYPGAKHG 719
Cdd:pfam01738 169 KAANVDHQIHSYPGAGHA 186
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 128-226 1.99e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 41.56  E-value: 1.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335  128 GGELYLYDLrkTGAAAIRkLTHGEGFATDAKLSPKGGFVSFVRER----NLWVIELASGNALQLTQDGSetigngvAEFV 203
Cdd:COG4946     40 AGDLWTVPA--DGGRARR-LTSHPGYESFPRFSPDGKWIAFTSDYdgntDVYVMPAEGGEPKRLTYHPA-------NDRV 109

                           90       100
                   ....*....|....*....|...
gi 1062071335  204 ADeemdrhtgywWAPDDSAIAFA 226
Cdd:COG4946    110 VG----------WTPDGKSVLFA 122
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 521-720 2.47e-03

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 39.98  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 521 IVYVYGGPAAQTV--LDAWPSRGDALFDQ--YLAQRgYVVFSLDNRGTPRRGRefggalygRQGTVEVDDQLQGVAWLRQ 596
Cdd:COG0596    14 LHYREAGPDGPPVvlLHGLPGSSYEWRPLipALAAG-YRVIAPDLRGHGRSDK--------PAGGYTLDDLADDLAALLD 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 597 QswVDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDWglYDTHYTERYMDLPA--RNAAGYRDARIATHLDGL 674
Cdd:COG0596    85 A--LGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAA--LAEPLRRPGLAPEAlaALLRALARTDLRERLARI 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1062071335 675 RAKLLLIHGMADDNVLFTNSTALMSALQQrgtpFELMTYPGAKHGL 720
Cdd:COG0596   161 TVPTLVIWGEKDPIVPPALARRLAELLPN----AELVVLPGAGHFP 202
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 519-645 5.70e-03

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 39.02  E-value: 5.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 519 PVIVYVYGGPAaqtVLDAWPSrgdalFDQYLAQRGYVVFSLDNRGTPRRGREfggalyGRQGTVEVDDQLQGVAWLRQQS 598
Cdd:pfam00561   1 PPVLLLHGLPG---SSDLWRK-----LAPALARDGFRVIALDLRGFGKSSRP------KAQDDYRTDDLAEDLEYILEAL 66

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1062071335 599 wvDAKRIGVQGWSNGGYMTLMLLAKRSDAYACGVAGAPVTDWGLYDT 645
Cdd:pfam00561  67 --GLEKVNLVGHSMGGLIALAYAAKYPDRVKALVLLGALDPPHELDE 111
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 31-173 6.78e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 40.02  E-value: 6.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335   31 PLPLSGPTL-MKPKVAPDGSRVTFlrgkdsDRNQLDLWEFDIASGQTRLLVDSKVvlpgtevlsdvekarrerqriaaFT 109
Cdd:COG4946    382 QLTLGDLGRvFNPVWSPDGKKIAF------TDNRGRLWVVDLASGKVRKVDTDGY-----------------------GD 432

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1062071335  110 GIVDYQWAPDAHALLFPLGG-----ELYLYDLRKTgaaAIRKLTHGEGFATDAKLSPKGGFVSFVRERN 173
Cdd:COG4946    433 GISDLAWSPDSKWLAYSKPGpnqlsQIFLYDVETG---KTVQLTDGRYDDGSPAFSPDGKYLYFLSSRD 498
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 547-720 8.25e-03

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 38.73  E-value: 8.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 547 QYLAQRGYVVFSLDNRGtprrgreFGGALyGRQGTVE-----VDDQLQGVAWLRQQsWVDAKRIgVQGWSNGGYMTLMLL 621
Cdd:pfam12146  25 DALAAQGFAVYAYDHRG-------HGRSD-GKRGHVPsfddyVDDLDTFVDKIREE-HPGLPLF-LLGHSMGGLIAALYA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1062071335 622 AKRSDAY--------ACGVAGAPVTDW------------------GLYDTHYTERYMD--------------LPARNAAG 661
Cdd:pfam12146  95 LRYPDKVdglilsapALKIKPYLAPPIlkllakllgklfprlrvpNNLLPDSLSRDPEvvaayaadplvhggISARTLYE 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1062071335 662 YRDA--RIATHLDGLRAKLLLIHGMADDNVLFTNSTALMSALqqRGTPFELMTYPGAKHGL 720
Cdd:pfam12146 175 LLDAgeRLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERA--GSTDKTLKLYPGLYHEL 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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