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Conserved domains on  [gi|1061225692|gb|AOH83333|]
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hypothetical protein AWL63_04450 [Sphingomonas panacis]

Protein Classification

TonB-dependent receptor( domain architecture ID 1003665)

TonB-dependent receptor may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0015891

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TonB-Xanth-Caul super family cl36973
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 58-908 1.74e-165

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


The actual alignment was detected with superfamily member TIGR01782:

Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 504.18  E-value: 1.74e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFRESLRSAAAAKRNDIRISDGITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYARTTINGQT 137
Cdd:TIGR01782   4 VQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLNGRT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 138 FASADFKD-GFRYDIIQTDLASAIQVVKSPTADMDTGGLSGTVNIDTVKPLGYKGPHFILGVKG--YDSQYRGGVTPKVS 214
Cdd:TIGR01782  84 IASTDSGGrAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGgyNDLAGKDKPGPRGA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 215 GAYINQFAGGTLGVMLNVGFQKLRDRGDYLFIKNWY---DPGVLLSDAYVPGNLRFRRIDRDTEQLMASGAIQWQPTSNF 291
Cdd:TIGR01782 164 ASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGtytSADGGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPSDAL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 292 EVLLQGEYSKDhtTYDTRQLVFGRWAASAVTVNHVANRVADKISISDFNVDNND-----QPELRNLASQAYTGTINWEPa 366
Cdd:TIGR01782 244 ELYLDTLYSKY--DDDETRQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQilveaRYNEEKETTTSLTLGGEWTG- 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 367 EGWKVHGVGHYTQGDAhlyeWASIDEVHFA----GGGTLDISDPSNVKFNTQNVNSGAPYTTANRTW-FAFLDGATHIQS 441
Cdd:TIGR01782 321 DRWTLDGDLGYSKATR----DRPDRVTRFFtaptPGYDFDYRGGPTLTLGTPADGDDASNYTNPANGeLRRTQISYQKAE 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 442 AKDTAGQLDITRDlGWHgvKALVFGVKYHHESFQTDAFRHdRDGDVTAPGTYPEHAFIPDLATTGVPvtNFLGGSMGIPS 521
Cdd:TIGR01782 397 DSEDAAQLDATFD-GPF--TSLKFGVRYRRRDKTNRGSRY-RRSIIGATGASGLAGVPSDLAGAGLD--GGLGGPLTGWD 470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 522 TFlSVNAPLWQ-SVLAQKGYTVPDTRDWPNTYRVDRYIPSVYGMFNIDGDIggkRLRGNIGVRYEHTHQ----NVTTSVT 596
Cdd:TIGR01782 471 PA-DLDAFLNAaRGDAAGGGTYTYASTAPNTYTVTEDTTAAYAMANFDTGL---RLRGNVGVRYERTDQtsdgWQSQPAA 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 597 NGTDSSAVLIGQEhivQDYGNVLPSASFALDLTPKLVARLALAKVLVRPLLNsqtQMADTISTSTSTSRPSVSVAQGESR 676
Cdd:TIGR01782 547 NGTGSVLVPVSAD---RDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFG---DLAANTSLSDDGTGGTVTVSGGNPD 620

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 677 LKPLTANQADISLEYYYGAGNSISLAGFYKAVKNGTFTQFYCPASYNGVALNgqttncqsadlKTDYSFSRVLNDSSTIH 756
Cdd:TIGR01782 621 LKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTSTETNDGGGGLV-----------VAGVLVSRPVNGGKAGK 689

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 757 IKGVEFSASQNFDpFLP--LKGFGATGNITYVDADSPA-----AGTGFHLRDLSKLTWNLTPYWENEMFSVRFSVNHRSS 829
Cdd:TIGR01782 690 IRGVELGYQQTFD-FLPgpLSGFGVQANYTYVDSEADPsvdgvQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSD 768

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1061225692 830 YQQDAADSFFVNGGeiHTVRARTQMDLALGFSPTKFLSFTGGIINLNNTHEDAYQTTEDTFQMASQTGRTFYLSATARF 908
Cdd:TIGR01782 769 YLLDVGGSNINRLD--RYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 58-908 1.74e-165

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 504.18  E-value: 1.74e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFRESLRSAAAAKRNDIRISDGITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYARTTINGQT 137
Cdd:TIGR01782   4 VQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLNGRT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 138 FASADFKD-GFRYDIIQTDLASAIQVVKSPTADMDTGGLSGTVNIDTVKPLGYKGPHFILGVKG--YDSQYRGGVTPKVS 214
Cdd:TIGR01782  84 IASTDSGGrAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGgyNDLAGKDKPGPRGA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 215 GAYINQFAGGTLGVMLNVGFQKLRDRGDYLFIKNWY---DPGVLLSDAYVPGNLRFRRIDRDTEQLMASGAIQWQPTSNF 291
Cdd:TIGR01782 164 ASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGtytSADGGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPSDAL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 292 EVLLQGEYSKDhtTYDTRQLVFGRWAASAVTVNHVANRVADKISISDFNVDNND-----QPELRNLASQAYTGTINWEPa 366
Cdd:TIGR01782 244 ELYLDTLYSKY--DDDETRQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQilveaRYNEEKETTTSLTLGGEWTG- 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 367 EGWKVHGVGHYTQGDAhlyeWASIDEVHFA----GGGTLDISDPSNVKFNTQNVNSGAPYTTANRTW-FAFLDGATHIQS 441
Cdd:TIGR01782 321 DRWTLDGDLGYSKATR----DRPDRVTRFFtaptPGYDFDYRGGPTLTLGTPADGDDASNYTNPANGeLRRTQISYQKAE 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 442 AKDTAGQLDITRDlGWHgvKALVFGVKYHHESFQTDAFRHdRDGDVTAPGTYPEHAFIPDLATTGVPvtNFLGGSMGIPS 521
Cdd:TIGR01782 397 DSEDAAQLDATFD-GPF--TSLKFGVRYRRRDKTNRGSRY-RRSIIGATGASGLAGVPSDLAGAGLD--GGLGGPLTGWD 470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 522 TFlSVNAPLWQ-SVLAQKGYTVPDTRDWPNTYRVDRYIPSVYGMFNIDGDIggkRLRGNIGVRYEHTHQ----NVTTSVT 596
Cdd:TIGR01782 471 PA-DLDAFLNAaRGDAAGGGTYTYASTAPNTYTVTEDTTAAYAMANFDTGL---RLRGNVGVRYERTDQtsdgWQSQPAA 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 597 NGTDSSAVLIGQEhivQDYGNVLPSASFALDLTPKLVARLALAKVLVRPLLNsqtQMADTISTSTSTSRPSVSVAQGESR 676
Cdd:TIGR01782 547 NGTGSVLVPVSAD---RDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFG---DLAANTSLSDDGTGGTVTVSGGNPD 620

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 677 LKPLTANQADISLEYYYGAGNSISLAGFYKAVKNGTFTQFYCPASYNGVALNgqttncqsadlKTDYSFSRVLNDSSTIH 756
Cdd:TIGR01782 621 LKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTSTETNDGGGGLV-----------VAGVLVSRPVNGGKAGK 689

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 757 IKGVEFSASQNFDpFLP--LKGFGATGNITYVDADSPA-----AGTGFHLRDLSKLTWNLTPYWENEMFSVRFSVNHRSS 829
Cdd:TIGR01782 690 IRGVELGYQQTFD-FLPgpLSGFGVQANYTYVDSEADPsvdgvQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSD 768

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1061225692 830 YQQDAADSFFVNGGeiHTVRARTQMDLALGFSPTKFLSFTGGIINLNNTHEDAYQTTEDTFQMASQTGRTFYLSATARF 908
Cdd:TIGR01782 769 YLLDVGGSNINRLD--RYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 82-908 9.33e-62

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 221.17  E-value: 9.33e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  82 DGITAEDIGKFPAQNVTEAIQRIAGVQMSNIN-GRGSTISIRGLGAQYARTTINGQTFASADFKDGFRYDIIQTDLASAI 160
Cdd:cd01347     3 SVITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIERV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 161 QVVKSPTADM-DTGGLSGTVNIDTVKPLGykgphfilgvkgydsQYRGGVTPKVSGAYINQFAGGTLGVMLNVGFqklRD 239
Cdd:cd01347    83 EVLKGPSSALyGSGAIGGVVNIITKRPTD---------------EFGGSVTAGYGSDNSGSSGGGGFDVSGALAD---DG 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 240 RGDYLFIKNWYDPgvllsDAYVPGNlrFRRIDRDTEQLMASGAIQWQPTSNFEVLLQGEYSKDHTTYDTRQLVFGRWAAS 319
Cdd:cd01347   145 AFGARLYGAYRDG-----DGTIDGD--GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSS 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 320 AvtvnhvanrvaDKISISDFNVDNNDQPELRNLASQAYTGTINWEPaEGWKVHGVGHYTQGDAHLYewasidevhfaggg 399
Cdd:cd01347   218 L-----------GGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLND-TGWTLRANLSYSYTDNDGD-------------- 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 400 tldisdpsnvkFNTQNVNSGAPYTTANRtwfaflDGATHIQSAKDTAGQLDITRDLGWHGVK-ALVFGVKYHHESFQTDA 478
Cdd:cd01347   272 -----------PLILNGGNNAAGGDLGR------SGYSSERDTTQLGFDAGLNAPFGTGPVAhTLTLGVEYRREELDEKQ 334

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 479 Frhdrdgdvtapgtypehafipdlattgvpvtnflggsmgipstflsvnaplwqsvlaqkgytvpdtrdwpntyrvdryi 558
Cdd:cd01347   335 T------------------------------------------------------------------------------- 335

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 559 pSVYGMFNIDGDIggkRLRGNIGVRYEHTHQNVTTSVTNGTDSSavligqehivQDYGNVLPSASFALDLTPKLVARLAL 638
Cdd:cd01347   336 -ALYAQDTIELTD---DLTLTLGLRYDHYDQDSKDTIAGGTTAK----------KSYSHWSPSLGLVYKLTDGLSLYASY 401

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 639 AKVLVRPLLNSQTQmadtiststsTSRPSVSVAQGESRLKPLTANQADISLEYYYGAGNSISLAGFYKAVKNGTFTQfyc 718
Cdd:cd01347   402 SQGFRAPSLGELYG----------GGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVST--- 468

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 719 pASYNGVALNGQTTNcqsadlktdysfsrvlndSSTIHIKGVEFSASQNFDPflplkGFGATGNITYVDA---DSPAAGT 795
Cdd:cd01347   469 -PTNTGLGLVTVYVN------------------GGKARIRGVELEASYDLTD-----GLGLTGSYTYTDTevkRTDGATT 524

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 796 GFHLRDLSKLTWNLTPYWE--NEMFSVRFSVNHRSSYQQDAAdsffvNGGEIHTVRARTQMDLALGFSPTKFLSFTGGII 873
Cdd:cd01347   525 GNRLPGIPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTA-----NGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVN 599

                         810       820       830
                  ....*....|....*....|....*....|....*....
gi 1061225692 874 NLNNTHedaYQTTEDTFQMASQT----GRTFYLSATARF 908
Cdd:cd01347   600 NLFDKD---YYTSLSVRGSGLYGyygpGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
58-879 1.15e-27

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 119.55  E-value: 1.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFR--ESLRSAAAAkrndirISDgITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYAR--TTI 133
Cdd:COG1629     4 VVVTATRtdESLQDVPGS------VSV-ISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNRvlVLV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 134 NGQTFASADFKDGFRyDIIQTDLASAIQVVKSPTADM-DTGGLSGTVNIDTVKPLGYKGPHFILGVKGYDsQYRGGVTpk 212
Cdd:COG1629    77 DGVPLNDPSGGDGGL-SYIDPEDIERVEVLRGPSSALyGSGALGGVINIVTKKPKDGKGGEVSASYGSYG-TYRASLS-- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 213 VSGayinqfAGGTLGVMLNVGFqklRDRGDYLfiknwydpgvllsdayvpGNLRFRRIDrdteqlmASGAIQWQPTSNFE 292
Cdd:COG1629   153 LSG------GNGKLAYRLSASY---RDSDGYR------------------DNSDSDRYN-------LRAKLGYQLGDDTR 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 293 VLLQGEYSKDHTTYDtrqlvfGRWAASAVTVNHVANRVADKISISDFNVDNNdqpelrnlasqAYTGTINWEP-AEGWKV 371
Cdd:COG1629   199 LTLSASYSDSDQDSP------GYLTLAALRPRGAMDDGTNPYSNDTDDNTRD-----------RYSLSLEYEHlGDGLKL 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 372 HGVGHYTQgdahlyewasidevhfagggtldisDPSNVKFNTQNVNSGAPYTTANRtwfafldgathiQSAKDTAGQLDI 451
Cdd:COG1629   262 SASAYYRY-------------------------DDTDLDSDFTPTPADGGTLEQTD------------FDNRTYGLELRL 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 452 TRDLGWHGVKALVFGVKYHHEsfqtdafRHDRDGDVTAPGtypehafipdlattgvpvtnflggsmgipstflsvnaplw 531
Cdd:COG1629   305 TYDLGFGGKHTLLVGLDYQRQ-------DLDGSGYPLDLG---------------------------------------- 337

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 532 qsvlaqKGYTVPDTRDWPNTYRVDRYipSVYGMFNIDGDiggKRLRGNIGVRYEHTHQNVTTSVTNGTDSSAvligqehi 611
Cdd:COG1629   338 ------SGSLPTLTSGADDDGTTTSL--ALYAQDTYKLT---DKLTLTAGLRYDYVSYDVDDTVTGTDSASG-------- 398

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 612 VQDYGNVLPSASFALDLTPKLVARLALAKVLVRPLLNSqtqmadtiststSTSRPSVSVAQGESRLKPLTANQADISLEY 691
Cdd:COG1629   399 SRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGE------------LYANGTDPYSVGNPDLKPETSTNYELGLRY 466

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 692 YYGAGN-SISLAGFYKAVKNGTFTQFYcpasYNGVALNGQTTNCQSAdlktdysfsrvlndsstiHIKGVEFSASQNFDP 770
Cdd:COG1629   467 RLLDGRlSLSLALFYSDVDNEILSVPL----PNDSGFSTYYTNAGKA------------------RSYGVELELSYQLTP 524

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 771 flplkGFGATGNITYVDA------DSPAAGTGFHLRDLSKLTWNLTPYWE-NEMFSVRFSVNHRSSYQQDAADSFFVNGG 843
Cdd:COG1629   525 -----GLSLNASYSYTDAkfdddtDGSADLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGAPGG 599

                         810       820       830
                  ....*....|....*....|....*....|....*.
gi 1061225692 844 eihtvraRTQMDLALGFSPTKFLSFTGGIINLNNTH 879
Cdd:COG1629   600 -------YTLVDLGAGYRFGDNLTLSLGVDNLFDKK 628
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 397-907 1.07e-21

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 99.46  E-value: 1.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 397 GGGTLDISDPSNVKFNTQNVNSGAPYTTANRTWFAFLDGATHIQSAKDTAGQLDITRDLGWHGVKALVFGVKYHHESFQT 476
Cdd:pfam00593  15 LTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDY 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 477 DAFRHDRDGDVTAPGTYPEHAFIPDLATTGVPVTNFLGGSMGIPSTFLSVNAPLWQSVLAQKGYTVPDTRDWPNTYRVDR 556
Cdd:pfam00593  95 TSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDTTTDS 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 557 YipSVYGMFNIDGDiggKRLRGNIGVRYEHTHQNVTTSVTNGTDSSavligqehivQDYGNVLPSASFALDLTPKLVARL 636
Cdd:pfam00593 175 Y--GLYLQDNIKLT---DRLTLTLGLRYDHYSTDGDDGNGGGDNFS----------RSYSAFSPRLGLVYKPTDNLSLYA 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 637 ALAKVLVRPLLNSQTqmadtistSTSTSRPSVSVAQGESRLKPLTANQADISLEYYYGAGNsISLAGFYKAVKNGTFTQf 716
Cdd:pfam00593 240 SYSRGFRAPSLGELY--------GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLS-LSLALFYIDIKNLITSD- 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 717 ycpasYNGVALNGQTTNCQSADlktdysfsrvlndssTIHIKGVEFSASQNFdpflpLKGFGATGNITYVDADSPAAG-- 794
Cdd:pfam00593 310 -----PDGPGLGGTVYTYTNVG---------------KARIRGVELELSGRL-----WGLGLSGGGYTYTDADDDADAdd 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 795 TGFHLRDLSKLTWNLTPYWENEMFsvRFSVNHRSSYQqDAADSFFVNGGEIHTVRARTQMDLALGFSPTKFLSFTGGIIN 874
Cdd:pfam00593 365 TGNPLPNVPRHTANLGLTYDFPLG--GWGARLGARYV-GSGERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNN 441

                         490       500       510
                  ....*....|....*....|....*....|....
gi 1061225692 875 L-NNTHEDAYQTTEDTFQMASQTGRTFYLSATAR 907
Cdd:pfam00593 442 LfDKYYKRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 58-190 1.91e-08

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 57.97  E-value: 1.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFRESLRSAAAAkrndirISDgITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYARTTINGQT 137
Cdd:PRK10064   35 VTASAVEQNLKDAPAS------ISV-ITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILIDGKR 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1061225692 138 FAS--ADFK-DGFRYDIIQTDLASAIQVVKSPTADM-DTGGLSGTVNIDTvKPLGYK 190
Cdd:PRK10064  108 VNSrnAVFRhNDFDLNWIPVDAIERIEVVRGPMSSLyGSDALGGVVNIIT-KKIGQK 163
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 58-908 1.74e-165

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 504.18  E-value: 1.74e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFRESLRSAAAAKRNDIRISDGITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYARTTINGQT 137
Cdd:TIGR01782   4 VQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLNGRT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 138 FASADFKD-GFRYDIIQTDLASAIQVVKSPTADMDTGGLSGTVNIDTVKPLGYKGPHFILGVKG--YDSQYRGGVTPKVS 214
Cdd:TIGR01782  84 IASTDSGGrAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGgyNDLAGKDKPGPRGA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 215 GAYINQFAGGTLGVMLNVGFQKLRDRGDYLFIKNWY---DPGVLLSDAYVPGNLRFRRIDRDTEQLMASGAIQWQPTSNF 291
Cdd:TIGR01782 164 ASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGtytSADGGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPSDAL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 292 EVLLQGEYSKDhtTYDTRQLVFGRWAASAVTVNHVANRVADKISISDFNVDNND-----QPELRNLASQAYTGTINWEPa 366
Cdd:TIGR01782 244 ELYLDTLYSKY--DDDETRQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQilveaRYNEEKETTTSLTLGGEWTG- 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 367 EGWKVHGVGHYTQGDAhlyeWASIDEVHFA----GGGTLDISDPSNVKFNTQNVNSGAPYTTANRTW-FAFLDGATHIQS 441
Cdd:TIGR01782 321 DRWTLDGDLGYSKATR----DRPDRVTRFFtaptPGYDFDYRGGPTLTLGTPADGDDASNYTNPANGeLRRTQISYQKAE 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 442 AKDTAGQLDITRDlGWHgvKALVFGVKYHHESFQTDAFRHdRDGDVTAPGTYPEHAFIPDLATTGVPvtNFLGGSMGIPS 521
Cdd:TIGR01782 397 DSEDAAQLDATFD-GPF--TSLKFGVRYRRRDKTNRGSRY-RRSIIGATGASGLAGVPSDLAGAGLD--GGLGGPLTGWD 470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 522 TFlSVNAPLWQ-SVLAQKGYTVPDTRDWPNTYRVDRYIPSVYGMFNIDGDIggkRLRGNIGVRYEHTHQ----NVTTSVT 596
Cdd:TIGR01782 471 PA-DLDAFLNAaRGDAAGGGTYTYASTAPNTYTVTEDTTAAYAMANFDTGL---RLRGNVGVRYERTDQtsdgWQSQPAA 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 597 NGTDSSAVLIGQEhivQDYGNVLPSASFALDLTPKLVARLALAKVLVRPLLNsqtQMADTISTSTSTSRPSVSVAQGESR 676
Cdd:TIGR01782 547 NGTGSVLVPVSAD---RDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFG---DLAANTSLSDDGTGGTVTVSGGNPD 620

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 677 LKPLTANQADISLEYYYGAGNSISLAGFYKAVKNGTFTQFYCPASYNGVALNgqttncqsadlKTDYSFSRVLNDSSTIH 756
Cdd:TIGR01782 621 LKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTSTETNDGGGGLV-----------VAGVLVSRPVNGGKAGK 689

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 757 IKGVEFSASQNFDpFLP--LKGFGATGNITYVDADSPA-----AGTGFHLRDLSKLTWNLTPYWENEMFSVRFSVNHRSS 829
Cdd:TIGR01782 690 IRGVELGYQQTFD-FLPgpLSGFGVQANYTYVDSEADPsvdgvQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSD 768

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1061225692 830 YQQDAADSFFVNGGeiHTVRARTQMDLALGFSPTKFLSFTGGIINLNNTHEDAYQTTEDTFQMASQTGRTFYLSATARF 908
Cdd:TIGR01782 769 YLLDVGGSNINRLD--RYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 82-908 9.33e-62

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 221.17  E-value: 9.33e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  82 DGITAEDIGKFPAQNVTEAIQRIAGVQMSNIN-GRGSTISIRGLGAQYARTTINGQTFASADFKDGFRYDIIQTDLASAI 160
Cdd:cd01347     3 SVITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIERV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 161 QVVKSPTADM-DTGGLSGTVNIDTVKPLGykgphfilgvkgydsQYRGGVTPKVSGAYINQFAGGTLGVMLNVGFqklRD 239
Cdd:cd01347    83 EVLKGPSSALyGSGAIGGVVNIITKRPTD---------------EFGGSVTAGYGSDNSGSSGGGGFDVSGALAD---DG 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 240 RGDYLFIKNWYDPgvllsDAYVPGNlrFRRIDRDTEQLMASGAIQWQPTSNFEVLLQGEYSKDHTTYDTRQLVFGRWAAS 319
Cdd:cd01347   145 AFGARLYGAYRDG-----DGTIDGD--GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSS 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 320 AvtvnhvanrvaDKISISDFNVDNNDQPELRNLASQAYTGTINWEPaEGWKVHGVGHYTQGDAHLYewasidevhfaggg 399
Cdd:cd01347   218 L-----------GGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLND-TGWTLRANLSYSYTDNDGD-------------- 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 400 tldisdpsnvkFNTQNVNSGAPYTTANRtwfaflDGATHIQSAKDTAGQLDITRDLGWHGVK-ALVFGVKYHHESFQTDA 478
Cdd:cd01347   272 -----------PLILNGGNNAAGGDLGR------SGYSSERDTTQLGFDAGLNAPFGTGPVAhTLTLGVEYRREELDEKQ 334

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 479 Frhdrdgdvtapgtypehafipdlattgvpvtnflggsmgipstflsvnaplwqsvlaqkgytvpdtrdwpntyrvdryi 558
Cdd:cd01347   335 T------------------------------------------------------------------------------- 335

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 559 pSVYGMFNIDGDIggkRLRGNIGVRYEHTHQNVTTSVTNGTDSSavligqehivQDYGNVLPSASFALDLTPKLVARLAL 638
Cdd:cd01347   336 -ALYAQDTIELTD---DLTLTLGLRYDHYDQDSKDTIAGGTTAK----------KSYSHWSPSLGLVYKLTDGLSLYASY 401

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 639 AKVLVRPLLNSQTQmadtiststsTSRPSVSVAQGESRLKPLTANQADISLEYYYGAGNSISLAGFYKAVKNGTFTQfyc 718
Cdd:cd01347   402 SQGFRAPSLGELYG----------GGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVST--- 468

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 719 pASYNGVALNGQTTNcqsadlktdysfsrvlndSSTIHIKGVEFSASQNFDPflplkGFGATGNITYVDA---DSPAAGT 795
Cdd:cd01347   469 -PTNTGLGLVTVYVN------------------GGKARIRGVELEASYDLTD-----GLGLTGSYTYTDTevkRTDGATT 524

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 796 GFHLRDLSKLTWNLTPYWE--NEMFSVRFSVNHRSSYQQDAAdsffvNGGEIHTVRARTQMDLALGFSPTKFLSFTGGII 873
Cdd:cd01347   525 GNRLPGIPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTA-----NGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVN 599

                         810       820       830
                  ....*....|....*....|....*....|....*....
gi 1061225692 874 NLNNTHedaYQTTEDTFQMASQT----GRTFYLSATARF 908
Cdd:cd01347   600 NLFDKD---YYTSLSVRGSGLYGyygpGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
58-879 1.15e-27

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 119.55  E-value: 1.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFR--ESLRSAAAAkrndirISDgITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYAR--TTI 133
Cdd:COG1629     4 VVVTATRtdESLQDVPGS------VSV-ISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNRvlVLV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 134 NGQTFASADFKDGFRyDIIQTDLASAIQVVKSPTADM-DTGGLSGTVNIDTVKPLGYKGPHFILGVKGYDsQYRGGVTpk 212
Cdd:COG1629    77 DGVPLNDPSGGDGGL-SYIDPEDIERVEVLRGPSSALyGSGALGGVINIVTKKPKDGKGGEVSASYGSYG-TYRASLS-- 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 213 VSGayinqfAGGTLGVMLNVGFqklRDRGDYLfiknwydpgvllsdayvpGNLRFRRIDrdteqlmASGAIQWQPTSNFE 292
Cdd:COG1629   153 LSG------GNGKLAYRLSASY---RDSDGYR------------------DNSDSDRYN-------LRAKLGYQLGDDTR 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 293 VLLQGEYSKDHTTYDtrqlvfGRWAASAVTVNHVANRVADKISISDFNVDNNdqpelrnlasqAYTGTINWEP-AEGWKV 371
Cdd:COG1629   199 LTLSASYSDSDQDSP------GYLTLAALRPRGAMDDGTNPYSNDTDDNTRD-----------RYSLSLEYEHlGDGLKL 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 372 HGVGHYTQgdahlyewasidevhfagggtldisDPSNVKFNTQNVNSGAPYTTANRtwfafldgathiQSAKDTAGQLDI 451
Cdd:COG1629   262 SASAYYRY-------------------------DDTDLDSDFTPTPADGGTLEQTD------------FDNRTYGLELRL 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 452 TRDLGWHGVKALVFGVKYHHEsfqtdafRHDRDGDVTAPGtypehafipdlattgvpvtnflggsmgipstflsvnaplw 531
Cdd:COG1629   305 TYDLGFGGKHTLLVGLDYQRQ-------DLDGSGYPLDLG---------------------------------------- 337

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 532 qsvlaqKGYTVPDTRDWPNTYRVDRYipSVYGMFNIDGDiggKRLRGNIGVRYEHTHQNVTTSVTNGTDSSAvligqehi 611
Cdd:COG1629   338 ------SGSLPTLTSGADDDGTTTSL--ALYAQDTYKLT---DKLTLTAGLRYDYVSYDVDDTVTGTDSASG-------- 398

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 612 VQDYGNVLPSASFALDLTPKLVARLALAKVLVRPLLNSqtqmadtiststSTSRPSVSVAQGESRLKPLTANQADISLEY 691
Cdd:COG1629   399 SRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGE------------LYANGTDPYSVGNPDLKPETSTNYELGLRY 466

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 692 YYGAGN-SISLAGFYKAVKNGTFTQFYcpasYNGVALNGQTTNCQSAdlktdysfsrvlndsstiHIKGVEFSASQNFDP 770
Cdd:COG1629   467 RLLDGRlSLSLALFYSDVDNEILSVPL----PNDSGFSTYYTNAGKA------------------RSYGVELELSYQLTP 524

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 771 flplkGFGATGNITYVDA------DSPAAGTGFHLRDLSKLTWNLTPYWE-NEMFSVRFSVNHRSSYQQDAADSFFVNGG 843
Cdd:COG1629   525 -----GLSLNASYSYTDAkfdddtDGSADLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGAPGG 599

                         810       820       830
                  ....*....|....*....|....*....|....*.
gi 1061225692 844 eihtvraRTQMDLALGFSPTKFLSFTGGIINLNNTH 879
Cdd:COG1629   600 -------YTLVDLGAGYRFGDNLTLSLGVDNLFDKK 628
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 40-869 2.69e-25

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 111.87  E-value: 2.69e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  40 VAAQASAGGQTDETVGPDITVTGFR--ESLRSAAAAKRNdirisdgITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRG- 116
Cdd:COG4771    12 LAAQAADALAEDATELEEVVVTATRteQSLSDAPASVSV-------ITAEEIEKLGATDLADALRLLPGVSVTRSGGRGg 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 117 -STISIRGLGAQYARTTINGQTFASADFKDGFRYDIIQTDLASAIQVVKSP-TADMDTGGLSGTVNIDTVKPLGYKGPHF 194
Cdd:COG4771    85 sSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDLSYIPPDDIERIEVIRGPaSALYGSDAIGGVINIITKKPTDELEGSV 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 195 ILgvkGYDSQYRGGVTpkvSGAYINqFAGGTLGVMLNVGFQKlrdrgdylfiknwydpgvllSDAYVPGNLRFRRIDRDT 274
Cdd:COG4771   165 SL---GYGSNGNGTYS---GSLSLG-GPGDKLSFLLSGSYRD--------------------RDGYLDYRNGGFVGNSGY 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 275 EQLMASGAIQWQPTSNFEVLLQGEYSKDHTTYDTRQLvfgrwaasavtvnhvanrvadkisisDFNVDNNDQPELRNLAS 354
Cdd:COG4771   218 ERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTL--------------------------GDTEISSDNAGDRDTTT 271

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 355 QAYTGTINWEPAEGWKVHGVGHYTQGDahlyewasidevhfagggtldisdpsNVKFNTQNVNSGAPYTTANRTWFAFld 434
Cdd:COG4771   272 DRGNYSLRYNGDLGDNLDLSLYYSRTD--------------------------RDSTNGSLGGSTGSFSDSDDTTYGL-- 323

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 435 gathiqsakdtagQLDITRDLGWHGVkaLVFGVKYHHESFQTDAFRHDRDGdvtapgtypehafipdlattgvpvtnflg 514
Cdd:COG4771   324 -------------ELDLTYPLGGNHT--LTLGAEYRYDDLDSSSFLGGADA----------------------------- 359

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 515 gsmgipstflsvnaplwqsvlaqkgytvpdtrdwpntyrvDRYIPSVYGMFNIDgdiGGKRLRGNIGVRYEHthqnvtTS 594
Cdd:COG4771   360 ----------------------------------------SRDTYGLFAQDEWK---LTDKLTLTAGLRYDY------YS 390

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 595 VTNGTdssavligqehivqDYGNVLPSASFALDLTPKLVARLALAKVlvrpllnsqTQMADTISTSTSTSRPSVSVAQGE 674
Cdd:COG4771   391 TFGAS--------------NYTAFSPRLGLRYDLSDNLTLRASYGRG---------FRAPSLAELYGSGTGTPGRYVLGN 447

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 675 SRLKPLTANQADISLEYYYGAGN-SISLAGFYKAVKNGTFTQFYCPASYNgvalNGQTTNcqsadlktdysfsrvlndSS 753
Cdd:COG4771   448 PDLKPETSDNYELGLEYRLGNGGlSLSLTGFYTDIKDLIVLVPVGPGPGD----VLQYEN------------------VG 505

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 754 TIHIKGVEFSASQNFDpflplKGFGATGNITYVDADSPAAGTGFHLRDLSKLTWNLTPYWENEMFSVRFSVNHRSSYQQD 833
Cdd:COG4771   506 KARTYGLELELKYRLG-----KGLTLTASYTYLDSKIDDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYV 580

                         810       820       830
                  ....*....|....*....|....*....|....*.
gi 1061225692 834 AADSFFVNGgeihTVRARTQMDLALGFSPTKFLSFT 869
Cdd:COG4771   581 TPPSGRLEG----YTPGYTLLDLRASYKLTKNLTLS 612
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 15-908 2.29e-22

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 103.05  E-value: 2.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  15 LLATSCVAAVATiapataqtapasDVAAQASAGGQTDETVGPDITVTGFRESL-----RSAAAAKRNDIRISD------G 83
Cdd:COG4773     4 LLAGSGLAAAAA------------GALAQAAAAAAAEATTLPEVTVTGTAEGTggytaKSSSTATKLDTPLREtpqsvsV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  84 ITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRG-STISIRGLGAQYArttingqtfasadFKDGFR---YDIIQTDLASA 159
Cdd:COG4773    72 VTRQLIEDQGATTLDDALRNVPGVTVSSYDGGGrDSFSIRGFSIDNY-------------LRDGLPlggFGGGQPDTANL 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 160 --IQVVKSPTADMD-TGGLSGTVNIDTVKPLGYKGPHFILGVKGYDsQYRGGVTpkVSGAyINqfAGGTLGVMLNVGFQK 236
Cdd:COG4773   139 erVEVLKGPAGLLYgAGSPGGLVNLVTKRPTAEPQGEVSLSAGSWD-TYRATAD--VGGP-LN--EDGTLRYRLNAAYED 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 237 lrdrgdylfiknwydpgvllSDAYVPGNlrfrridrDTEQLMASGAIQWQPTSNFEVLLQGEYSKDHTTYDTRQLvfgrw 316
Cdd:COG4773   213 --------------------GDSFRDGV--------DNRRTLIAPSLDWDLTDDTTLTLGAEYQDDDSTGDRGFL----- 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 317 aasavtvnhVANRVADKISISDFNVDNNDQpelRNLASQAYTGTINWEPAEGWKVHGVGHYTQGDAHLYEwasidevHFA 396
Cdd:COG4773   260 ---------PLDGTLLDLPRSTNLGEPWDY---YDTETTTLFAELEHRFNDDWSLRANARYSDSDRDGRS-------AYA 320

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 397 GGGTLDisdpsnvkfNTQNVNSGAPYTTANRTWFAFldgathiqsakdtagQLDITRDLGWHGVKA-LVFGVkyhhesfq 475
Cdd:COG4773   321 YGAPDA---------ATGTLTRYASARDGDSRSDSL---------------DANLNGKFETGGLEHtLLVGA-------- 368

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 476 tDAFRHDRDGDvtapgtypehafipDLATTGVPVTNFLGGSmgipstflsvnaplwqsvlaqkgYTVPDTRDWPNTYRVD 555
Cdd:COG4773   369 -DYSRYDSDSD--------------SATAGTINIYNPVYGN-----------------------LPEPDFDASDTDTTTR 410

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 556 RYipSVYGM--FNIdgdigGKRLRGNIGVRYEHTHQNVTTSVTNGTDSsavligqehivQDYGNVLPSASFALDLTPKLV 633
Cdd:COG4773   411 QT--GLYAQdqISL-----TDRLSLLLGGRYDWYETDSTNRLGGSTTS-----------YDDSAFTPRAGLVYDLTPGLS 472

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 634 ARLALAKVlvrplLNSQTQMAdtistststsrpsvsvAQGESrLKPLTANQADISLEYYYGAGN-SISLAgFYKAVKNGT 712
Cdd:COG4773   473 LYASYSES-----FEPQSGAD----------------NNGNP-LDPETGKQYEAGVKGELFDGRlNATLA-VFDITQKNV 529

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 713 FTQfycpasyngvalNGQTTNCQSADlktdysfsrvlndsSTIHIKGVEFSASQNfdpflPLKGFGATGNITYVDA---D 789
Cdd:COG4773   530 ATT------------DPDNPNFYVQV--------------GEVRSRGVELELSGE-----LTPGLNLIAGYTYTDAkitK 578

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 790 SPAAGTGFHLRDLSKLTWNLT-----PYWENEMFSVRFSVNHRSSYQQDAADSFfvnggeihTVRARTQMDLALGFSPTK 864
Cdd:COG4773   579 DADALEGKRLTNVPRHTASLWttyrfPSGALKGLGLGGGVRYVGERYGDAANTF--------TLPSYTLVDAGARYDLGK 650

                         890       900       910       920
                  ....*....|....*....|....*....|....*....|....*
gi 1061225692 865 FLSFTggiINLNN-THEDAYQTTEDTFQMASQTGRTFYLSATARF 908
Cdd:COG4773   651 NWTLQ---LNVNNlFDKKYYASSGSRGYVYYGAPRNVRLSLSYKF 692
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 397-907 1.07e-21

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 99.46  E-value: 1.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 397 GGGTLDISDPSNVKFNTQNVNSGAPYTTANRTWFAFLDGATHIQSAKDTAGQLDITRDLGWHGVKALVFGVKYHHESFQT 476
Cdd:pfam00593  15 LTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDY 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 477 DAFRHDRDGDVTAPGTYPEHAFIPDLATTGVPVTNFLGGSMGIPSTFLSVNAPLWQSVLAQKGYTVPDTRDWPNTYRVDR 556
Cdd:pfam00593  95 TSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDTTTDS 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 557 YipSVYGMFNIDGDiggKRLRGNIGVRYEHTHQNVTTSVTNGTDSSavligqehivQDYGNVLPSASFALDLTPKLVARL 636
Cdd:pfam00593 175 Y--GLYLQDNIKLT---DRLTLTLGLRYDHYSTDGDDGNGGGDNFS----------RSYSAFSPRLGLVYKPTDNLSLYA 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 637 ALAKVLVRPLLNSQTqmadtistSTSTSRPSVSVAQGESRLKPLTANQADISLEYYYGAGNsISLAGFYKAVKNGTFTQf 716
Cdd:pfam00593 240 SYSRGFRAPSLGELY--------GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLS-LSLALFYIDIKNLITSD- 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 717 ycpasYNGVALNGQTTNCQSADlktdysfsrvlndssTIHIKGVEFSASQNFdpflpLKGFGATGNITYVDADSPAAG-- 794
Cdd:pfam00593 310 -----PDGPGLGGTVYTYTNVG---------------KARIRGVELELSGRL-----WGLGLSGGGYTYTDADDDADAdd 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 795 TGFHLRDLSKLTWNLTPYWENEMFsvRFSVNHRSSYQqDAADSFFVNGGEIHTVRARTQMDLALGFSPTKFLSFTGGIIN 874
Cdd:pfam00593 365 TGNPLPNVPRHTANLGLTYDFPLG--GWGARLGARYV-GSGERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNN 441

                         490       500       510
                  ....*....|....*....|....*....|....
gi 1061225692 875 L-NNTHEDAYQTTEDTFQMASQTGRTFYLSATAR 907
Cdd:pfam00593 442 LfDKYYKRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
58-364 8.19e-17

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 81.84  E-value: 8.19e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFR--ESLRSAAAAkrndiriSDGITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRG--STISIRGLGAQYARTTI 133
Cdd:COG4206     1 VVVTATRleQSKSDLTGS-------VTVIDAEELERSGATSLADALRRVPGVQVSSSGGPGsaASISIRGLGSNQTLVLI 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 134 NGQTFASADFkDGFRYDIIQTDLASAIQVVKSPTADM-DTGGLSGTVNIDTVKPLGYKGPHFILGVKGYDSQyrggvtpK 212
Cdd:COG4206    74 DGVPLNDPSL-GGVDLSLIPPDDIERIEVLKGAASALyGSDAIGGVINITTKKGKKGFKGSVSASYGSFGTR-------R 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 213 VSGAYinQFAGGTLGVMLNVGFQKlrdrgdylfiknwydpgvllSDAYVPGNLRFRRIDrDTEQLMASGAIQWQPTSNFE 292
Cdd:COG4206   146 LSASL--SGGAGKFSYSLSASYRR--------------------SDGYRYNDPDLRNND-GYENTSLNARLGYKLGDNGS 202

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1061225692 293 VLLQGEYSKDHTTYDTRQLVFGRWAASaVTVNHVANRVADKISISDFNVDNNDQPELRNLASQAYTGTINWE 364
Cdd:COG4206   203 LSLSGGYSDSERGYPGAVGSDRNLRLS-LSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAG 273
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 84-178 2.07e-14

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 69.99  E-value: 2.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  84 ITAEDIGKFPAQNVTEAIQRIAGVQMSN-INGRGSTISIRGLGAQYARTTINGQTFASADFkDGFRYDIIQTDLASAIQV 162
Cdd:pfam07715  12 VTAEDIEDQGATNLADALRGVPGVSVSSgGGGGGSSISIRGFGSNRVLVLVDGVPLNSGGG-GSVDLNSIDPEDIERVEV 90

                          90
                  ....*....|....*..
gi 1061225692 163 VKSP-TADMDTGGLSGT 178
Cdd:pfam07715  91 LKGPaSALYGSGAIGGV 107
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
40-908 1.26e-12

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 71.50  E-value: 1.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  40 VAAQASAGGQTDETVGPDITVTGFRESLRSAAAAKRNDIRIsdgiTAEDIGKFPAQNVTEAIQRIAGVQMSNINGRG--S 117
Cdd:COG4772     8 ALLLAAAAAAEAATTLETVVVTGSRAAEARLKDVPGSVSVV----DREELENQAATSLREVLRRVPGVNVQEEDGFGlrP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 118 TISIRGLGAQY-ARTTI--NGQTFASADFKDGFRYDIIQTDLASAIQVVKSPTADM---DTGGlsGTVNIDTvkPLGYKG 191
Cdd:COG4772    84 NIGIRGLGPRRsRGITLleDGIPIAPAPYGDPAAYYFPDLERMERIEVLRGAAALRygpQTVG--GAINFVT--RTIPTA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 192 PHFILGVkgydsqyRGGvtpkvSGAYINQFA--GGTLGvmlNVGFQklrdrGDYLFIKnwydpgvllSDAYVPGNlrfrr 269
Cdd:COG4772   160 FGGELRV-------TGG-----SFGYRRTHAsvGGTVG---NFGYL-----VEYSRKR---------GDGFRDNS----- 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 270 iDRDTEQLMASGAIQWQPTSNFEVLLQGeyskdhttYDTRQLVFGrwaasavtvnhvanrvadkiSISDFNVDNNdqpel 349
Cdd:COG4772   206 -GFDINDFNAKLGYRLSDRQELTLKFQY--------YDEDANTPG--------------------GLTDAQFDAD----- 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 350 rnlASQAYTGTINWEpaegwkvhgvGHYTQGDAHlYEWasidevhfagggtlDISDpsNVKFNTQNVnsgapYTTANRTW 429
Cdd:COG4772   252 ---PRQSYRPADQFD----------TRRTQLSLR-YEH--------------QLSD--NTTLTTTAY-----YNDFSRNW 296

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 430 FAFLDGATHIQSA----------KDTAGQLDITRDLGWHGVKA-LVFGVKYHHESFqtDAFRHDrdgdvtapGTYPehaf 498
Cdd:COG4772   297 YIRQNTADPNTPGlglrgnprgyRSYGIEPRLTHRFELGGVPHtLEVGLRYHREEE--DRKQYV--------NTYG---- 362

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 499 ipdlattgvpvtnflggsmgipstflsvnaplwqsvLAQKGYTVPDTRDWPNTYRvdryipSVYGM--FNIDGdiggkRL 576
Cdd:COG4772   363 ------------------------------------QGRSGAGLRRDRRFSADAL------AAYAQnrFELTG-----RL 395

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 577 RGNIGVRYEHTHQNVT--TSVTNGTDSSAvligqehiVQDYGNVLPSASFALDLTPKLVARLALAKvLVRPLLNSQtqma 654
Cdd:COG4772   396 TLTPGLRYEHIRRDRTdrYSTRTGGDDSG--------SNSYSEFLPGLGLLYQLTDNLQLYANVSR-GFEPPTFGD---- 462

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 655 dtistststsrpSVSVAQGESRLKPLTANQADISLEYYYGAGNSISLAGFYKAVKNgtftqfycpasyngvalngQTTNC 734
Cdd:COG4772   463 ------------LAYGNGGNPDLKPEKSWNYELGTRGRIGNGLSAEVALFYIDYDN-------------------ELGSC 511

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 735 QSADLKTDYSFsrvlNDSSTIHiKGVEFSASQNFDPFlPLKGFGATGNITYVDA----DSPAAGTGFHLRDLSKLTWNLT 810
Cdd:COG4772   512 SAAGGDRSTFT----NAGETRH-QGLELALDYDLLKG-GGLGLPLFAAYTYTDAeftsDFGPVFAGNRLPYVPRHQLTAG 585

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 811 PYWENEMFSVRFSVNHRSSYQQDAADSffVNGGEIHTVRARTQMDLALGFSPTKFLSFTGGIINLNNTHE--DAYQTTED 888
Cdd:COG4772   586 LGYEHGGWTANLNGRYVSEQFTDAANT--VADGSFGKIPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYiaSRAPNYAA 663

                         890       900
                  ....*....|....*....|
gi 1061225692 889 TFQMAsqTGRTFYLSATARF 908
Cdd:COG4772   664 GIRPG--PPRTVYAGLRLKF 681
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 58-190 1.91e-08

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 57.97  E-value: 1.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFRESLRSAAAAkrndirISDgITAEDIGKFPAQNVTEAIQRIAGVQMSNINGRGSTISIRGLGAQYARTTINGQT 137
Cdd:PRK10064   35 VTASAVEQNLKDAPAS------ISV-ITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILIDGKR 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1061225692 138 FAS--ADFK-DGFRYDIIQTDLASAIQVVKSPTADM-DTGGLSGTVNIDTvKPLGYK 190
Cdd:PRK10064  108 VNSrnAVFRhNDFDLNWIPVDAIERIEVVRGPMSSLyGSDALGGVVNIIT-KKIGQK 163
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
58-305 1.27e-06

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 52.32  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  58 ITVTGFRESLRSAAAAkrndIRIsdgITAEDIGKFPAQNVTEAIQRIAGVQMsNINGRGSTISIRGLGAQYARTTING-- 135
Cdd:PRK13484   35 VTASGFTQQLRNAPAS----VSV---ITSEQLQKKPVSDLVDAVKDVEGISI-TGGNEKPDISIRGLSGDYTLILVDGrr 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 136 ------QTFASADFKDGFrydIIQTDLASAIQVVKSPTADM-DTGGLSGTVNIDTvKPLGYKGPHFILGVkgydsqyrgg 208
Cdd:PRK13484  107 qsgresRPNGSGGFEAGF---IPPVEAIERIEVIRGPMSSLyGSDAIGGVINIIT-KPVNNQTWDGVLGL---------- 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 209 vtpkvsgayinqfaGGTLgvmlnvgfQKLRDRGDYLfIKNWYDPGVLLSDAY---VPGNLRFRRID--------RDTEQL 277
Cdd:PRK13484  173 --------------GGII--------QEHGKFGNST-TNDFYLSGPLIKDKLglqLYGGMNYRKEDsisqgtpaKDNKNI 229

                         250       260
                  ....*....|....*....|....*....
gi 1061225692 278 MASgaIQWQPTSNFEVLLQ-GEYSKDHTT 305
Cdd:PRK13484  230 TAT--LQFTPTESQKFVFEyGKNNQVHTL 256
PRK13513 PRK13513
ligand-gated channel protein;
40-136 9.74e-05

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 46.30  E-value: 9.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  40 VAAQASAGGQTDETVGPDITVT---GFRESLRSAAAAkrndirISDgITAEDIGKFPAQNVTEAIQRIAGVQmsnINGRG 116
Cdd:PRK13513   19 ISSQAYAAEKTNTATPTDTMVVtasGFQQRIQDAPAS------ISV-VTREQLENKAYRDVTDALKDVPGVV---VTGGG 88

                          90       100
                  ....*....|....*....|..
gi 1061225692 117 ST--ISIRGLGAQYARTTINGQ 136
Cdd:PRK13513   89 STsdISIRGMAAKYTLILVDGK 110
PRK13483 PRK13483
ligand-gated channel protein;
15-136 3.26e-04

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 44.38  E-value: 3.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  15 LLATSCVAAVATIAPataqtapasdVAAQASAGgQTDETVGpdITVTGFRESLRSAAAAkrndirISDgITAEDIGKFPA 94
Cdd:PRK13483    8 VISALCLLPAVFVTH----------ALAQAAPD-KTMETVV--VTASGYEQQIRDAPAS------ISV-ITREDLENRFY 67

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1061225692  95 QNVTEAIQRIAGVqmsNINGRGST--ISIRGLGAQYARTTINGQ 136
Cdd:PRK13483   68 RDLTDALLDVPGV---VVTGGGDRtdISLRGMGSQYTLILVDGK 108
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
 550-631 3.23e-03

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 40.72  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 550 NTYRVDRYIPSVYGMFNIDGdiggKRLRGNIGVRYEHTHQNVTTSVTNGTDSsavligqehivQDYGNVLPSASFALDLT 629
Cdd:pfam14905 106 NDFDYKENIYAAYASYSKKF----GKWSYQAGLRAEYTDIDGDSVTTNETFK-----------RNYFNLFPSASLSYKLN 170


                  ..
gi 1061225692 630 PK 631
Cdd:pfam14905 171 DN 172
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
40-186 4.70e-03

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 40.78  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692  40 VAAQASAGGQTDETVGPDITVTGFRESLRSAAAAKrndirisdgITAEDIGKFPAQN-VTEAIQRIAGVQM---SNINGR 115
Cdd:PRK13524   23 AEAEDAKTDDTPASHEDTIVVTAAEQNLQAPGVST---------ITAEDIRKRPPANdVSEIIRTMPGVNLtgnSTSGQR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1061225692 116 GST--ISIRGLGAQYARTTINGQTFASadfKDGFRY------------DIIQTDLASAIQVVKSPTADM-DTGGLSGTVN 180
Cdd:PRK13524   94 GNNrqIDIRGMGPENTLILIDGKPVSS---RNSVRYgwrgerdtrgdtNWVPPEMIERIEVLRGPAAARyGNGAAGGVVN 170


                  ....*.
gi 1061225692 181 IDTVKP 186
Cdd:PRK13524  171 IITKKP 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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