|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-441 |
1.62e-160 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 461.07 E-value: 1.62e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 1 MNIHFISIGGSVMHQLAIALKRKGYQITGSDDEIFePAKSNLEKEGLlPSVIGWFPERITGAlDAVLLGMHAKADNPELI 80
Cdd:COG0773 5 MHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAES-PMTERLEALGI-PVFIGHDAENIDDA-DLVVVSSAIPRDNPELV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 81 KAKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYLVGARLEGFNQSVDITDAPIIVCEAD 160
Cdd:COG0773 82 AARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAEAD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 161 EYPASaierrpkFHFLFPHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRKdIHY 240
Cdd:COG0773 162 ESDGS-------FLHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRP-VIT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 YP------YSVPSYTISNGETR--VCIEGEETA---LKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLE 309
Cdd:COG0773 234 YGfsedadYRAENIRIDGGGSTfdVLRRGEELGeveLNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 310 LLSKNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSLNEqFMTEYKDVLNVAEEAAVYYSKHALElKR 389
Cdd:COG0773 314 LKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRD-FLDEFAEALSLADEVILLDIYAARE-KP 391
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 1054634375 390 MPELKKEMVKAGFGKE--NLQVLNQKQELEQWLAERQFDNSVVLLMSSGNYDGM 441
Cdd:COG0773 392 IPGVSSEDLAEAIRKRgkDVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGL 445
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
2-375 |
2.05e-77 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 247.99 E-value: 2.05e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 2 NIHFISIGGSVMHQLAIALKRKGYQITGSDDEIFEPAKSnLEKEGLlPSVIGWFPERITGAlDAVLLGMHAKADNPELIK 81
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKR-LEALGI-PIYIGHSAENLDDA-DVVVVSAAIKDDNPEIVE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 82 AKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYLVGARLEGFNQSVDITDAPIIVCEADE 161
Cdd:TIGR01082 78 AKERGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARLGSGEYLVAEADE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 162 YPASaierrpkFHFLFPHIAILTGIAWDHI-NVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRKDIHY 240
Cdd:TIGR01082 158 SDAS-------FLHLQPNVAIVTNIEPDHLdTYGSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKATEQVITY 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 YP------YSVPSYTISNGETRVCIEG-----EETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLE 309
Cdd:TIGR01082 231 GGsgedadYRAENIQQSGAEGKFSVRGkgklyLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRFE 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1054634375 310 LLSKNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSLnEQFMTEYKDVLNVAEE 375
Cdd:TIGR01082 311 ILGEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRT-RDLFDDFAKVLSDADE 375
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
4-368 |
2.54e-30 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 124.54 E-value: 2.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 4 HFISIGGSVMHQLAIALKRKGYQITGSDdeIFE-PAKSNLEKEG---LLPSVIGWFPERITgaldaVLLGMHAKADNPEL 79
Cdd:PRK14573 8 HFIGIGGIGMSALAHILLDRGYSVSGSD--LSEgKTVEKLKAKGarfFLGHQEEHVPEDAV-----VVYSSSISKDNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 80 IKAKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYLVGA-RLEGFNQSVDITDapIIVCE 158
Cdd:PRK14573 81 LSAKSRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGlNQEGLNGYSGSSE--YFVAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 159 ADEYPASaierrpkFHFLFPHIAILTGIAWDHINVFP-TFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRK- 236
Cdd:PRK14573 159 ADESDGS-------LKHYTPEFSVITNIDNEHLSNFEgDRELLLASIQDFARKVQQINKCFYNGDCPRLKGCLQGHSYGf 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 237 ----DIHYYPYSVPSYTISNGETRVCIEGEETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLELLS 312
Cdd:PRK14573 232 ssscDLHILSYYQEGWRSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRRLERKN 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1054634375 313 KNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSLNE---QFMTEYKD 368
Cdd:PRK14573 312 SSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLREcldSFPSAFQD 370
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
108-280 |
1.00e-13 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 69.64 E-value: 1.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 108 VGGSHGKTTTTAMLMHVLKNAGKSFdYLVGARLEG----FNQSVDI---------TDAPIIVCEADEYpaSAIERRPKFh 174
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVI-GTIGTYIGKsgntTNNAIGLpltlaemveAGAEYAVLEVSSH--GLGEGRLSG- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 175 FLFPHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLV------------------ASIGRK 236
Cdd:pfam08245 77 LLKPDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIaklkkagvrvitygiegeADLRAA 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1054634375 237 DIHYYPYSVPSYTISNGETRVCIEgeetaLKVFGNHNLLNMHAA 280
Cdd:pfam08245 157 NIELSSDGTSFDLFTVPGGELEIE-----IPLLGRHNVYNALAA 195
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-441 |
1.62e-160 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 461.07 E-value: 1.62e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 1 MNIHFISIGGSVMHQLAIALKRKGYQITGSDDEIFePAKSNLEKEGLlPSVIGWFPERITGAlDAVLLGMHAKADNPELI 80
Cdd:COG0773 5 MHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAES-PMTERLEALGI-PVFIGHDAENIDDA-DLVVVSSAIPRDNPELV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 81 KAKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYLVGARLEGFNQSVDITDAPIIVCEAD 160
Cdd:COG0773 82 AARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAEAD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 161 EYPASaierrpkFHFLFPHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRKdIHY 240
Cdd:COG0773 162 ESDGS-------FLHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRP-VIT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 YP------YSVPSYTISNGETR--VCIEGEETA---LKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLE 309
Cdd:COG0773 234 YGfsedadYRAENIRIDGGGSTfdVLRRGEELGeveLNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 310 LLSKNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSLNEqFMTEYKDVLNVAEEAAVYYSKHALElKR 389
Cdd:COG0773 314 LKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRD-FLDEFAEALSLADEVILLDIYAARE-KP 391
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 1054634375 390 MPELKKEMVKAGFGKE--NLQVLNQKQELEQWLAERQFDNSVVLLMSSGNYDGM 441
Cdd:COG0773 392 IPGVSSEDLAEAIRKRgkDVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGL 445
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
2-375 |
2.05e-77 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 247.99 E-value: 2.05e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 2 NIHFISIGGSVMHQLAIALKRKGYQITGSDDEIFEPAKSnLEKEGLlPSVIGWFPERITGAlDAVLLGMHAKADNPELIK 81
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKR-LEALGI-PIYIGHSAENLDDA-DVVVVSAAIKDDNPEIVE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 82 AKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYLVGARLEGFNQSVDITDAPIIVCEADE 161
Cdd:TIGR01082 78 AKERGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARLGSGEYLVAEADE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 162 YPASaierrpkFHFLFPHIAILTGIAWDHI-NVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRKDIHY 240
Cdd:TIGR01082 158 SDAS-------FLHLQPNVAIVTNIEPDHLdTYGSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKATEQVITY 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 YP------YSVPSYTISNGETRVCIEG-----EETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLE 309
Cdd:TIGR01082 231 GGsgedadYRAENIQQSGAEGKFSVRGkgklyLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRFE 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1054634375 310 LLSKNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSLnEQFMTEYKDVLNVAEE 375
Cdd:TIGR01082 311 ILGEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRT-RDLFDDFAKVLSDADE 375
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
17-337 |
1.43e-35 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 136.75 E-value: 1.43e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 17 AIALKRKGYQITGSDD-EIFEPAKSNLEKEGLlPSVIGWFPERITGALDAVLL--GMhaKADNPELIKAKELGLPIYSFP 93
Cdd:COG0771 20 ARLLAKLGAEVTVSDDrPAPELAAAELEAPGV-EVVLGEHPEELLDGADLVVKspGI--PPDHPLLKAARAAGIPVIGEI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 94 EYIYKESQNKTrVAVGGSHGKTTTTAMLMHVLKNAGKSFdYLVGarlegfN--QSV-----DITDAPIIVCEAdeypaSA 166
Cdd:COG0771 97 ELAYRLSPAPI-IAITGTNGKTTTTTLIGHILKAAGLRV-AVGG------NigTPLldlllEPEPPDVYVLEL-----SS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 167 --IERRPKFHflfPHIAILTGIAWDHINVFPTFDNYLE-QFRIFINKiEPEGYLIYNEGDQTLKDLVASIGRKdihYYPY 243
Cdd:COG0771 164 fqLETTPSLR---PDVAVILNITPDHLDRHGSMEAYAAaKARIFANQ-TPDDYAVLNADDPLTRALAEEAKAR---VVPF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 244 SV-----PSYTISNGETRVCIEGEE----TALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLELLSKN 314
Cdd:COG0771 237 SLkepleGGAGLEDGKLVDRASGEEllpvDDLRLPGRHNLENALAALAAARALGVPPEAIREALRSFKGLPHRLEFVAEI 316
|
330 340
....*....|....*....|....
gi 1054634375 315 NTTTVYRDfahapSkvKAT-IDAV 337
Cdd:COG0771 317 NGVRFIND-----S--KATnPDAT 333
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
4-368 |
2.54e-30 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 124.54 E-value: 2.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 4 HFISIGGSVMHQLAIALKRKGYQITGSDdeIFE-PAKSNLEKEG---LLPSVIGWFPERITgaldaVLLGMHAKADNPEL 79
Cdd:PRK14573 8 HFIGIGGIGMSALAHILLDRGYSVSGSD--LSEgKTVEKLKAKGarfFLGHQEEHVPEDAV-----VVYSSSISKDNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 80 IKAKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYLVGA-RLEGFNQSVDITDapIIVCE 158
Cdd:PRK14573 81 LSAKSRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGlNQEGLNGYSGSSE--YFVAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 159 ADEYPASaierrpkFHFLFPHIAILTGIAWDHINVFP-TFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRK- 236
Cdd:PRK14573 159 ADESDGS-------LKHYTPEFSVITNIDNEHLSNFEgDRELLLASIQDFARKVQQINKCFYNGDCPRLKGCLQGHSYGf 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 237 ----DIHYYPYSVPSYTISNGETRVCIEGEETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLELLS 312
Cdd:PRK14573 232 ssscDLHILSYYQEGWRSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRRLERKN 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1054634375 313 KNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSLNE---QFMTEYKD 368
Cdd:PRK14573 312 SSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLREcldSFPSAFQD 370
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
6-338 |
2.47e-28 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 116.29 E-value: 2.47e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 6 ISIGGSVMHQLAIA--LKRKGYQITGSDDEIFEPAKSNLEKEGLLPSVI---GWFPERITGAlDAVLLGMHAKADNPELI 80
Cdd:TIGR01087 2 ILILGLGKTGRAVArfLHKKGAEVTVTDLKPNEELEPSMGQLRLNEGSVlhtGLHLEDLNNA-DLVVKSPGIPPDHPLVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 81 KAKELGLPIYSFPEYIYKESQNKTrVAVGGSHGKTTTTAMLMHVLKNAGksFDYLVG-----ARLEGFNQsvdiTDAPII 155
Cdd:TIGR01087 81 AAAKRGIPVVGDIELFLRLVPLPV-VAITGTNGKTTTTSLLYHLLKAAG--LKAFLGgnigtPALEVLDQ----EGAELY 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 156 VCEADEYpasAIERRPKFHflfPHIAILTGIAWDHINVFPTFDNYLE-QFRIFINKIEPEgYLIYNEGDQTLkdlVASIG 234
Cdd:TIGR01087 154 VLELSSF---QLETTESLR---PEIALILNISEDHLDWHGSFEDYVAaKLKIFARQTEGD-VAVLNADDPRF---ARLAQ 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 235 RKDIHYYPYSVPSYTisngETRVCIEGEETALKVF-------GNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKR 307
Cdd:TIGR01087 224 KSKAQVIWFSVEKDA----ERGLCIRDGGLYLKPNdlegsllGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHR 299
|
330 340 350
....*....|....*....|....*....|....
gi 1054634375 308 LELLSKNNTTTVYRDfahapSK---VKATIDAVK 338
Cdd:TIGR01087 300 LEYVGQKNGVHFYND-----SKatnVHATLAALS 328
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
20-309 |
9.13e-28 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 114.68 E-value: 9.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 20 LKRKGYQITGSDDEIFEPAKSNLEKEGLLPS--VIGWFPERITGALDAVLLGMHAKADNPELIKAKELGLPIYSFPEYIY 97
Cdd:PRK14106 24 LKKLGAKVILTDEKEEDQLKEALEELGELGIelVLGEYPEEFLEGVDLVVVSPGVPLDSPPVVQAHKKGIEVIGEVELAY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 98 KESQnKTRVAVGGSHGKTTTTAMLMHVLKNAGksFDYLVGARLeGF---NQSVDITDAPIIVCEADEYPASAIER-RPKf 173
Cdd:PRK14106 104 RFSK-APIVAITGTNGKTTTTTLLGEIFKNAG--RKTLVAGNI-GYpliDAVEEYGEDDIIVAEVSSFQLETIKEfKPK- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 174 hflfphIAILTGIAWDHINVFPTFDNYLE-QFRIFINkIEPEGYLIYNEGDQTLKDLVASIGRKDIHYYPYSV--PSYTI 250
Cdd:PRK14106 179 ------VGCILNITPDHLDRHKTMENYIKaKARIFEN-QRPSDYTVLNYDDPRTRSLAKKAKARVIFFSRKSLleEGVFV 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1054634375 251 SNGETRVCIEGEETA------LKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLE 309
Cdd:PRK14106 252 KNGKIVISLGGKEEEvidideIFIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEHRIE 316
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
106-432 |
1.14e-17 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 84.77 E-value: 1.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 106 VAVGGSHGKTTTTAMLMHVLKNAGK------SF-----------------DYLVgarLE-GFNQSVDItdapiivceadE 161
Cdd:COG0770 103 IAITGSNGKTTTKEMLAAVLSTKGKvlatpgNFnneigvpltllrlpedhEFAV---LEmGMNHPGEI-----------A 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 162 YPASAIErrpkfhflfPHIAILTGIAWDHINVFPTFDN-YLEQFRIFiNKIEPEGYLIYNEGDQTLKDLVASIGRKdIHY 240
Cdd:COG0770 169 YLARIAR---------PDIAVITNIGPAHLEGFGSLEGiARAKGEIF-EGLPPGGVAVLNADDPLLAALAERAKAR-VLT 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 Y------PYSVPSYTISNGETRVCI----EGEETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLEL 310
Cdd:COG0770 238 FglsedaDVRAEDIELDEDGTRFTLhtpgGELEVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGRLEV 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 311 LSKNNTTTVYRDFAHA-PSKVKATIDAVKEQFPDRKLVALL----ELHTYSSlneqfmTEYKDVLNVAEEA---AVY--- 379
Cdd:COG0770 318 IEGAGGVTLIDDSYNAnPDSMKAALDVLAQLPGGGRRIAVLgdmlELGEESE------ELHREVGELAAELgidRLFtvg 391
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1054634375 380 -YSKHALElkrmpelkkemvkaGFGKENLQVLNQKQELEQWLAERQFDNSVVLL 432
Cdd:COG0770 392 eLARAIAE--------------AAGGERAEHFEDKEELLAALKALLRPGDVVLV 431
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
98-349 |
3.89e-14 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 74.74 E-value: 3.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 98 KESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYL--VGARLEGFNQSVDITDA-PIIV------CEADEYPASAIE 168
Cdd:PRK11929 107 RPSEQLSLVAVTGTNGKTSCAQLLAQLLTRLGKPCGSIgtLGARLDGRLIPGSLTTPdAIILhrilarMRAAGADAVAME 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 169 ---------RRPKFHFlfpHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRKD-I 238
Cdd:PRK11929 187 asshgleqgRLDGLRI---AVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAARLLAALPRGLkV 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 239 HYYPYSVPS----------YTISNGETRVCIEGEETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRL 308
Cdd:PRK11929 264 GYSPQNAGAdvqardlratAHGQVFTLATPDGSYQLVTRLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAVSPVPGRM 343
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1054634375 309 ELLSK---NNTTTVYRDFAHAPSKVKATIDAVK--EQFPDRKLVAL 349
Cdd:PRK11929 344 ERVGPtagAQGPLVVVDYAHTPDALAKALTALRpvAQARNGRLVCV 389
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
108-280 |
1.00e-13 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 69.64 E-value: 1.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 108 VGGSHGKTTTTAMLMHVLKNAGKSFdYLVGARLEG----FNQSVDI---------TDAPIIVCEADEYpaSAIERRPKFh 174
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVI-GTIGTYIGKsgntTNNAIGLpltlaemveAGAEYAVLEVSSH--GLGEGRLSG- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 175 FLFPHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLV------------------ASIGRK 236
Cdd:pfam08245 77 LLKPDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIaklkkagvrvitygiegeADLRAA 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1054634375 237 DIHYYPYSVPSYTISNGETRVCIEgeetaLKVFGNHNLLNMHAA 280
Cdd:pfam08245 157 NIELSSDGTSFDLFTVPGGELEIE-----IPLLGRHNVYNALAA 195
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
106-349 |
9.05e-13 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 69.72 E-value: 9.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 106 VAVGGSHGKTTTTAMLMHVLKNAGKSFDYL--VGARLEGFNQSVDIT--DAPII-----VCEADEYPASAIE-------- 168
Cdd:COG0769 83 IGVTGTNGKTTTTYLLAQILRALGKKTGLIgtVGNGIGGELIPSSLTtpEALDLqrllaEMVDAGVTHVVMEvsshaldq 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 169 RRPK-FHFlfpHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGD-------QTLKDLVASIGRKDIHY 240
Cdd:COG0769 163 GRVDgVRF---DVAVFTNLTRDHLDYHGTMEAYFAAKARLFDQLGPGGAAVINADDpygrrlaAAAPARVITYGLKADAD 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 YpySVPSYTISNGETRVCIEGE----ETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAAKRLELLSKNNT 316
Cdd:COG0769 240 L--RATDIELSADGTRFTLVTPggevEVRLPLIGRFNVYNALAAIAAALALGIDLEEILAALEKLKGVPGRMERVDGGQG 317
|
250 260 270
....*....|....*....|....*....|...
gi 1054634375 317 TTVYRDFAHAPSKVKATIDAVKEqFPDRKLVAL 349
Cdd:COG0769 318 PTVIVDYAHTPDALENVLEALRP-HTKGRLIVV 349
|
|
| PRK14022 |
PRK14022 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase; |
95-350 |
1.71e-12 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase;
Pssm-ID: 237588 [Multi-domain] Cd Length: 481 Bit Score: 68.91 E-value: 1.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 95 YIYKESQNKTrVAVGGSHGKTTTTAMLMHVLKNAGKsfdylvGARLEGFN----------------QSVDIT-------- 150
Cdd:PRK14022 103 YDNPQHKLKL-LAFTGTKGKTTAAYFAYHILKQLHK------PAMLSTMNttldgetffksalttpESLDLFkmmaeavd 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 151 -DAPIIVCEADEYpASAIERRPKFHFlfpHIAILTGIAWDHINVF--PTFDNYLEQFRIFINKiepEGYLIYNEGDQTLK 227
Cdd:PRK14022 176 nGMTHLIMEVSSQ-AYLVGRVYGLTF---DVGVFLNITPDHIGPIehPTFEDYFYHKRLLMEN---SKAVVVNSDMDHFS 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 228 DLVASIGRKDIHYY-PYSVPSYTISNG---ETRVCIEGEeTALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSfTG 303
Cdd:PRK14022 249 ELLEQVTPQEHDFYgIDSENQIMASNAfsfEATGKLAGT-YDIQLIGKFNQENAMAAGLACLRLGASLEDIQKGIAQ-TP 326
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1054634375 304 AAKRLELLSKNNTTTVYRDFAHAPSKVKATIDAVKEqFPDRKLVALL 350
Cdd:PRK14022 327 VPGRMEVLTQSNGAKVFIDYAHNGDSLNKLIDVVEE-HQKGKLILLL 372
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
100-349 |
8.40e-11 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 63.61 E-value: 8.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 100 SQNKTRVAVGGSHGKTTTTAMLMHVLKNAGK------SfdylVGARLEGFNQSVDIT--DAPiivcEADEYPASAIERRP 171
Cdd:PRK00139 92 SDKLKLIGVTGTNGKTTTAYLLAQILRLLGEktaligT----LGNGIGGELIPSGLTtpDAL----DLQRLLAELVDAGV 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 172 KF------------------HFlfpHIAILTGIAWDHINVFPTFDNYLE-QFRIF--------INKIEPEGYLIYNEGDq 224
Cdd:PRK00139 164 TYaamevsshaldqgrvdglKF---DVAVFTNLSRDHLDYHGTMEDYLAaKARLFselglaavINADDEVGRRLLALPD- 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 225 tlkdlVASIGRKDIHYYpysVPSYTISNGETRVCIEGEETaLKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGA 304
Cdd:PRK00139 240 -----AYAVSMAGADLR---ATDVEYTDSGQTFTLVTEVE-SPLIGRFNVSNLLAALAALLALGVPLEDALAALAKLQGV 310
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1054634375 305 AKRLELLSKNNTTTVYRDFAHAPSKVKATIDAVKEqFPDRKLVAL 349
Cdd:PRK00139 311 PGRMERVDAGQGPLVIVDYAHTPDALEKVLEALRP-HAKGRLICV 354
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
96-435 |
1.03e-10 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 63.95 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 96 IYKESQNKTRVAVGGSHGKTTTTAMLM----------HVLKNAGkSFDYLVGARLEGFNQSVDiTDAPIIVCEAD----- 160
Cdd:PRK11929 596 AWRARFSLPVVAITGSNGKTTTKEMIAailaawqgedRVLATEG-NFNNEIGVPLTLLRLRAQ-HRAAVFELGMNhpgei 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 161 EYPASAIErrpkfhflfPHIAILTGIAWDHINVFPTFDNYLEQFRIFINKIEPEGYLIYNEGDQTLKDLVASIGRKDIHY 240
Cdd:PRK11929 674 AYLAAIAA---------PTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYTAIWAKLAGARRVLR 744
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 241 YPY--SVPSY------TISNGE-----TRVCIEGE--ETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAA 305
Cdd:PRK11929 745 FGLqpGADVYaekiakDISVGEaggtrCQVVTPAGsaEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVA 824
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 306 KRLELLSKNNTTTVYRDFAHA-PSKVKATIDAVKEQFPDRKLVAL---LELHTYSSlneqfmTEYKDVLNVAEEAAVYY- 380
Cdd:PRK11929 825 GRMQRRRLSCGTRIIDDTYNAnPDSMRAAIDVLAELPNGPRALVLgdmLELGDNGP------AMHREVGKYARQLGIDAl 898
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1054634375 381 ---SKHALELKRmpelkkemvkaGFGKENLQVLNQKQELEQWLAERQFDNSVVLLMSS 435
Cdd:PRK11929 899 itlGEAARDAAA-----------AFGAGARGVCASVDEIIAALRGALPEGDSVLIKGS 945
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
94-349 |
4.37e-10 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 61.56 E-value: 4.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 94 EYIYKESQNKTRVAVGGSHGKTTTTAMLMHVLKNAGKSFDYL--VGARLEGFNQSVDIT-----DAPII----------- 155
Cdd:TIGR01085 76 AFYGHPSKKLKVIGVTGTNGKTTTTSLIAQLLRLLGKKTGLIgtIGYRLGGNDLIKNPAalttpEALTLqstlaemveag 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 156 ----VCEADEYpASAIERRPKFHFLfphIAILTGIAWDHINVFPTFDNYLE-----------QFRIFINKIEPEG----- 215
Cdd:TIGR01085 156 aqyaVMEVSSH-ALAQGRVRGVRFD---AAVFTNLSRDHLDFHGTMENYFAakaslftelglKRFAVINLDDEYGaqfvk 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 216 --------YLIYNEGDQTLKDLVAsigrKDIHYYPYSVPSYTISNGETRVCiegeETALkvFGNHNLLNMHAAWLVCKQL 287
Cdd:TIGR01085 232 rlpkditvSAITQPADGRAQDIKI----TDSGYSFEGQQFTFETPAGEGHL----HTPL--IGRFNVYNLLAALATLLHL 301
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1054634375 288 G-ISAKAFVHAIGSFTGAAKRLELLSKNNTTTVYRDFAHAPSKVKATIDAVKEqFPDRKLVAL 349
Cdd:TIGR01085 302 GgIDLEDIVAALEKFRGVPGRMELVDGGQKFLVIVDYAHTPDALEKALRTLRK-HKDGRLIVV 363
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
3-96 |
1.10e-06 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 46.46 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1054634375 3 IHFISIGGSVMHQLAIALKRKGYQITGSDdeifepAKSNLEKEGLlpsvigwfperitgaldAVLLGMHA----KADNPE 78
Cdd:pfam01225 2 IHFVGIDGRGMSPGALFLALKGYRVDGSD------FIESLIALGA-----------------AAVVGHDAanniSPDNPE 58
|
90
....*....|....*...
gi 1054634375 79 LIKAKELGLPIYSFPEYI 96
Cdd:pfam01225 59 LEAAKVPGIPVIDRREAL 76
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
307-347 |
5.37e-05 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 41.56 E-value: 5.37e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1054634375 307 RLELLSKNNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLV 347
Cdd:pfam02875 4 RLEVVGENNGVLVIDDYAHNPDAMEAALRALRNLFPGRLIL 44
|
|
| PRK14016 |
PRK14016 |
cyanophycin synthetase; Provisional |
106-130 |
1.09e-03 |
|
cyanophycin synthetase; Provisional
Pssm-ID: 237586 [Multi-domain] Cd Length: 727 Bit Score: 41.30 E-value: 1.09e-03
10 20
....*....|....*....|....*
gi 1054634375 106 VAVGGSHGKTTTTAMLMHVLKNAGK 130
Cdd:PRK14016 483 VAVTGTNGKTTTTRLIAHILKLSGK 507
|
|
| |
