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Conserved domains on  [gi|1047475633|gb|ANW46921|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Isophya cania]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-313 1.26e-75

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 235.10  E-value: 1.26e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMtllLNQP 80
Cdd:MTH00160   11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM---LFNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 LFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYvIFMNTFLSMVVMSSIIIGSLGGLNQTS 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSY-LINNNFIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 161 LRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFL-MKLPPSMKFWLFFLLLSLGGV 239
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNsNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1047475633 240 PPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFSLSWQEISWFEISPKNTSYYVILLMLS 313
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFLSF 320
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-313 1.26e-75

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 235.10  E-value: 1.26e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMtllLNQP 80
Cdd:MTH00160   11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM---LFNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 LFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYvIFMNTFLSMVVMSSIIIGSLGGLNQTS 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSY-LINNNFIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 161 LRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFL-MKLPPSMKFWLFFLLLSLGGV 239
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNsNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1047475633 240 PPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFSLSWQEISWFEISPKNTSYYVILLMLS 313
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFLSF 320
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 14-271 7.52e-29

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 112.02  E-value: 7.52e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  14 APTWFTSWMGLEINLLSFIPLM-INTKNTMSTEAALKYFLIQALASSIFLFTVILMH--------------FNNMTLLLN 78
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYnytgtlsfdelskaLTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVL-MTWQKIAPFMLI-------SYVIFMNTFLSMVVMSSIII 150
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 151 GSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGETY----WLFYFGVYSFLSTSLVALFQA-----SQLFYINQTF-LMK 220
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGgLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1047475633 221 LPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITT 271
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 5-281 8.31e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 98.26  E-value: 8.31e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   5 LSGTLISVSAPTWFTSWMGLEINLLSFIPL-MINTKNTMSTEAALKYFLIQALASSIFLFTVIL-------MHFNNMTLL 76
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatgsLNLAGIAAA 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  77 LNQPLFLTLLSSSLLL--------KMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPF---------MLISYVIFMNTF 139
Cdd:COG1007   192 LAAGGANSPLLLLGLVlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveAFPGLAADWQLL 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 140 LSMVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGETYW----LFYFGVYSFLSTSLVALFQA-SQLFYIN 214
Cdd:COG1007   272 LAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGvsaaLFYLLAYLFMNLGAFAVILLlSRKGGEA 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1047475633 215 QTF-----LMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:COG1007   352 EEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-315 1.79e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.38  E-value: 1.79e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEINLLSFIPLM-INTKNTMSTEAALKYFLIQALASSIFLFTVILM-------HFNNMTLLLN 78
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslNFEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSS--------LLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIA---PFMLISYVIFMN------TFLS 141
Cdd:TIGR01770 194 NGMLNISLLLLgivlilvgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFGfseawqIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 142 MVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTA----GETYWLFYFGVYSFLS----TSLVALFQA---SQL 210
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtleGIKAVLFYIFIYALMSlgafGVLSLLRSYkdeWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 211 FYINQTFLMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLA---FTSFS 287
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVkvmYFDKP 433

                         330       340
                  ....*....|....*....|....*...
gi 1047475633 288 LSWQEISWFEISPKNTSYYVILLMLSTG 315
Cdd:TIGR01770 434 ERRIPSNPQSKAQSLLLSISALFILFLG 461
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-313 1.26e-75

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 235.10  E-value: 1.26e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMtllLNQP 80
Cdd:MTH00160   11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM---LFNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 LFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYvIFMNTFLSMVVMSSIIIGSLGGLNQTS 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSY-LINNNFIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 161 LRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFL-MKLPPSMKFWLFFLLLSLGGV 239
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNsNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1047475633 240 PPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFSLSWQEISWFEISPKNTSYYVILLMLS 313
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFLSF 320
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 2-314 1.54e-61

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 199.30  E-value: 1.54e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   2 ITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVI--LMHFNNMTLL-LN 78
Cdd:MTH00105   11 LTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIinLMYSGQWTITkLT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFML---ISYVIFMNTFLSMVVMsSIIIGSLGG 155
Cdd:MTH00105   91 NPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIlyqISPSINPNLLLTLAIL-SILIGGWGG 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 156 LNQTSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFLM--KLPPsMKFWLFFLL 233
Cdd:MTH00105  170 LNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTwnKTPL-MTSLILLTL 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 234 LSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSF-----SLSWQEISWFEISPKNTSYYVI 308
Cdd:MTH00105  249 LSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSltmfpSTNNMKMKWQFENTKPMTLLPT 328


                  ....*.
gi 1047475633 309 LLMLST 314
Cdd:MTH00105  329 LIILST 334
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 3-285 8.68e-55

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 181.56  E-value: 8.68e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   3 TLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVIL---MHFNNMTLLLNQ 79
Cdd:MTH00112   12 SLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTnawNTGQWDITQLTN 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  80 PLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLIsYVIFMN---TFLSMVVMSSIIIGSLGGL 156
Cdd:MTH00112   92 PTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLL-LMTSNSlnpTLLLTLAILSTLIGGWGGL 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 157 NQTSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLvalfqasqLFYINQTFLMKLP---------PSMKF 227
Cdd:MTH00112  171 NQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPM--------FLTLNTTSTKTLKdmmtswtksPTLNT 242

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1047475633 228 WLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTS 285
Cdd:MTH00112  243 TLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYIS 300
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-304 1.80e-54

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 180.90  E-value: 1.80e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMTLLLNQP 80
Cdd:MTH00041   10 ITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 LFLTLLSSSLL---LKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVI-FMNTFLSMVV-MSSIIIGSLGG 155
Cdd:MTH00041   90 LNTLSSIIITLalaLKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISnLLNSNILILCgILSVLVGGWGG 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 156 LNQTSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYI-NQTFLMKLPPSMKFWLFFLLL 234
Cdd:MTH00041  170 LNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLsHLNKLSQLNPISAFLFILSIL 249

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 235 SLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFSLSWQEISWFEISPKNTS 304
Cdd:MTH00041  250 SLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSG 319
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 4-284 1.91e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 178.19  E-value: 1.91e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   4 LLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNN---MTLLLNQP 80
Cdd:MTH00070   13 LALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTgewTIMNMQTP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 LFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVI-FMNTFLSMVV-MSSIIIGSLGGLNQ 158
Cdd:MTH00070   93 LPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQIShLLNSNLLIIMgLLSTLIGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 159 TSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQ--TFLMKLPPsMKFWLFFLLLSL 236
Cdd:MTH00070  173 TQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKlsSSWSKNPT-LTSMMMLTLLSL 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1047475633 237 GGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFT 284
Cdd:MTH00070  252 GGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYA 299
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-287 5.34e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 173.92  E-value: 5.34e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMTLLLnqp 80
Cdd:MTH00144   10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 lfLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMNTFLSMVVMSSI---IIGSLGGLN 157
Cdd:MTH00144   87 --MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVlsaLVGSIGGLN 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 158 QTSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFLMKLPPSMKFWLFFLLLSLG 237
Cdd:MTH00144  165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLG 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475633 238 GVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFS 287
Cdd:MTH00144  245 GLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-294 6.40e-50

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 168.80  E-value: 6.40e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHfnnMTLLLNQP 80
Cdd:MTH00011   12 SSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMW---SFPSLLKN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  81 LFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMN--TFLSMVVMSSIIIGSLGGLNQ 158
Cdd:MTH00011   89 ITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNilPMMTSMAAMSALAGGLGGMNQ 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 159 TSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQ-TFLMKLPPSMKFWLFFLLLSLG 237
Cdd:MTH00011  169 TQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFnSKISSMSQTTSMSLFIMLLSLG 248

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1047475633 238 GVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFSLSWQEIS 294
Cdd:MTH00011  249 GLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 2-314 7.70e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 168.31  E-value: 7.70e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   2 ITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMTLLLnqpl 81
Cdd:MTH00197    5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLL---- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  82 FLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMNTFLSMVVMSSIIIGSLGGLNQTSL 161
Cdd:MTH00197   81 SVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSNI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 162 RKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFLMKLPPSM-KFWLFFLLLSLGGVP 240
Cdd:MTH00197  161 RQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSnLVFLGLSFLSLGGLP 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1047475633 241 PFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSFSLS-WQEISWFEISPKNTSYYVILLMLST 314
Cdd:MTH00197  241 PLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSnWMINFLMKINLLYSGLFILLMMMLP 315
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 7-284 3.04e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 167.29  E-value: 3.04e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVIL-------MHFNNMTlllnQ 79
Cdd:MTH00135   16 GTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTnawltgqWDIQQMS----H 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  80 PLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMN-TFLSMVVMSSIIIGSLGGLNQ 158
Cdd:MTH00135   92 PLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNpTLLITLGLTSTLVGGWGGLNQ 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 159 TSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINqTFLMKLP--PSMKFWLFFLLLSL 236
Cdd:MTH00135  172 TQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKIN-TLATSWTkaPALTALTPLILLSL 250

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1047475633 237 GGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFT 284
Cdd:MTH00135  251 GGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYA 298
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-285 5.88e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 158.98  E-value: 5.88e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMTLLLNQ- 79
Cdd:MTH00200   10 ILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEm 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  80 --PLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMNTFLSMVVMS--SIIIGSLGG 155
Cdd:MTH00200   90 lgPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGllSVLVGGWGG 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 156 LNQTSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYSFLSTSLVALFQASQLFYINQTFLMKLP-PSMKFWLFFLLL 234
Cdd:MTH00200  170 LNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKnPILSMLLGLTLL 249

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1047475633 235 SLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTS 285
Cdd:MTH00200  250 SLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLT 300
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 14-271 7.52e-29

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 112.02  E-value: 7.52e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  14 APTWFTSWMGLEINLLSFIPLM-INTKNTMSTEAALKYFLIQALASSIFLFTVILMH--------------FNNMTLLLN 78
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYnytgtlsfdelskaLTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVL-MTWQKIAPFMLI-------SYVIFMNTFLSMVVMSSIII 150
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 151 GSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGETY----WLFYFGVYSFLSTSLVALFQA-----SQLFYINQTF-LMK 220
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGgLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1047475633 221 LPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITT 271
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 7-281 2.53e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 98.56  E-value: 2.53e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTM-STEAALKYFLIQALASSIFLF-------TVILMHFNNMTLLLN 78
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGySAEAGLKYFVLGALSSGLFLFgcallcgTTGGLHLSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 Q---------PLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMNTFLSMVVMSSII 149
Cdd:MTH00196   85 SgqsfssvsvPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSLF 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 150 IGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGE----TYWLFYFGVYSFLST---SLVALFQASQLFYINQTFLMKLP 222
Cdd:MTH00196  165 VGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSIcvfSIILALNVYKNLIIEFSGLSRRL 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1047475633 223 PSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:MTH00196  245 PILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 5-281 8.31e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 98.26  E-value: 8.31e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   5 LSGTLISVSAPTWFTSWMGLEINLLSFIPL-MINTKNTMSTEAALKYFLIQALASSIFLFTVIL-------MHFNNMTLL 76
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatgsLNLAGIAAA 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  77 LNQPLFLTLLSSSLLL--------KMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPF---------MLISYVIFMNTF 139
Cdd:COG1007   192 LAAGGANSPLLLLGLVlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveAFPGLAADWQLL 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 140 LSMVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGETYW----LFYFGVYSFLSTSLVALFQA-SQLFYIN 214
Cdd:COG1007   272 LAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGvsaaLFYLLAYLFMNLGAFAVILLlSRKGGEA 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1047475633 215 QTF-----LMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:COG1007   352 EEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 7-281 8.95e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 97.78  E-value: 8.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEINLLS-FIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMH-------FNNMTLLLN 78
Cdd:MTH00199  109 GSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYgltgetsIQGINSILT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMNTFLSMVVMSSIIIGSLGGLNQ 158
Cdd:MTH00199  189 GDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIGALNQ 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 159 TSLRKIMAYSSINHSGWMLAALTAGE----TYWLFYFGVY---SFLSTSLVALFQASQLFYINQTFLMKLPPSMKFWLFF 231
Cdd:MTH00199  269 TKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYvimSICSFSIILSLKLTKGLIVEVSGLSRKNPVIALTLAL 348

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475633 232 LLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:MTH00199  349 TFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
7-281 1.71e-22

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 97.20  E-value: 1.71e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEI-NLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVIL-------MHFNNMTLLLN 78
Cdd:PRK05777  115 GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLlygatgsLSFAGIAKALA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSS--------LLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFML---ISYVIFMNT------FLS 141
Cdd:PRK05777  195 DGSGNSLLLLFglvfllvgLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVllrLLVVAFGGLsedwqqVLA 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 142 MVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGET--------YWLFY-------FGVYSFLSTslvALFQ 206
Cdd:PRK05777  275 IIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAegysavlfYLLAYlfmtlgaFGVISLLRR---KGGE 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1047475633 207 ASQLFYINQtfLMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:PRK05777  352 AESISDFAG--LSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-315 1.79e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.38  E-value: 1.79e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEINLLSFIPLM-INTKNTMSTEAALKYFLIQALASSIFLFTVILM-------HFNNMTLLLN 78
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslNFEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  79 QPLFLTLLSSS--------LLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIA---PFMLISYVIFMN------TFLS 141
Cdd:TIGR01770 194 NGMLNISLLLLgivlilvgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAifaVFLRLFLYILFGfseawqIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 142 MVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTA----GETYWLFYFGVYSFLS----TSLVALFQA---SQL 210
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtleGIKAVLFYIFIYALMSlgafGVLSLLRSYkdeWIE 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 211 FYINQTFLMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLA---FTSFS 287
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVkvmYFDKP 433

                         330       340
                  ....*....|....*....|....*...
gi 1047475633 288 LSWQEISWFEISPKNTSYYVILLMLSTG 315
Cdd:TIGR01770 434 ERRIPSNPQSKAQSLLLSISALFILFLG 461
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-281 3.69e-16

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 78.27  E-value: 3.69e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   1 FITLLSGTLISVSAPTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFN----NMTLL 76
Cdd:COG0651   113 FLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGAtgtlNMADL 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  77 ------LNQPLFLTLLSSSLL---LKMGAAPFHFWFPGTM-EGLSWMNCLV--LMTwqKIAPFMLI--SYVIF---MNTF 139
Cdd:COG0651   193 aarlaeLDPGLLLAAFALLLVgfgIKAALFPLHFWLPDAYpAAPSPVSALLsgLLT--KVGVYAILrvLTLLFgadPALF 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 140 LSMVVMS----SIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGeTYWLFYFGVYSFLSTSLV--ALFQAS-QLFY 212
Cdd:COG0651   271 LGTLLLVlgllTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLG-TPLGLAGALFHLLNHALAkaLLFLAAgAIER 349

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1047475633 213 INQTF-------LMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:COG0651   350 ATGTRdldklggLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 7-293 1.21e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 71.43  E-value: 1.21e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   7 GTLISVSAPTWFTSWMGLEINLLSFIPL---------MINTKNTMSTEAALKYFLIQALASSIFLF-------------- 63
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFgcalyfgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  64 --TVILMHFNNMTLLLNQPLF-LTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCLVLMTWQKIAPFMLISYVIFMNTFL 140
Cdd:MTH00198  280 lgTILSATLETTNIELRQGSLgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKLL 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 141 SMVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGE--------TYWLFYFgVYSFLSTSLVALFQASQLFY 212
Cdd:MTH00198  360 LSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTyeslqaswTYAVTYL-VSALASFTVICTLEEFGTRT 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 213 INQ-------------------TFLMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLV------IQSLASLEHIFLLTVM 267
Cdd:MTH00198  439 PTSrqrdgsfgnynlvrrlvdlTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFIlvgsikIAFSSSLSIYYLVALF 518

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 1047475633 268 -VITTLLTLFYYLRLAFT----------------SFSLSWQEI 293
Cdd:MTH00198  519 aIICTCISAFYYIRIVATiyfnftrpliktktplSFILTWESI 561
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 24-281 1.71e-12

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 67.60  E-value: 1.71e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  24 LEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFN----NMTLLLNQP-------LFLTLLSSSLLL 92
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVtgtlNMADLAGALaenptvvTAFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  93 KMGAAPFHFWFPGTM-EGLSWMNCLVLMTWQKIAPFML--ISYVIF---------MNTFLSMVVMSSIIIGSLGGLNQTS 160
Cdd:PRK08375  215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYALirIYFTVFggdfrfalgLGWLLAVLALLSMLVGSLAALGQDD 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 161 LRKIMAYSSINHSGWML--------AALTAGetywLFYFGVYSFLSTSLV----ALFQASQLFYINQ-TFLMKLPPSMKF 227
Cdd:PRK08375  295 VKRVLAYSTVSQMGYILlglalltpLALAAG----LLHLLHHALMKGALFlaagAIEVTYGTRRLSElSGLGRRMPLTAA 370

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1047475633 228 WLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:PRK08375  371 AFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRI 424
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 45-286 7.43e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 56.64  E-value: 7.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  45 EAALKYFLIQALASSIFLFTVILMH--FNNMTL-----------LLNQPLFLTLLSSSLLLKMGAAPFHFWFP-GTMEGL 110
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIALLYgqYGTLNMaylavkmsenpTVVAKIALALFIAGLAMKSGAVPVHMWLPdAYPAAP 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 111 SWMNCLVLMTWQ-KIAPFMLISYVIFMNTFLSMVV--------MSSIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALT 181
Cdd:PRK08376  252 SSISAMLLVIKQaGLYALARVLFSIYGPAINLATVgwviiilgCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLG 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 182 AGetywLFYFGVYSFLSTSLVALfqASQLFYINQTFLMK------------------------LPPSMKFWLFFLL---L 234
Cdd:PRK08376  332 VG----LAALGDPAMASYGEIAL--AGGIYHIVNHALYKallfltagaviyetgtrnlnelggLARTMPKTTIAFLigaA 405

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1047475633 235 SLGGVPPFMGFMPKWLVIQSLASLeHIFLLTVMVITTLLTLFYYLRLAFTSF 286
Cdd:PRK08376  406 AIVGLPPFNGFASKWLIYESSALF-NPILGVIAMIGSVLTLASFVKVFHTAF 456
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
43-280 7.87e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.52  E-value: 7.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  43 STEAALKYFLIQALASSIFLFTVILMH----------------FNNMTLLLnqPLFLTLLSSSLLLKMGAAPFHFWFPGT 106
Cdd:PRK02504  159 SNEAALKYLLIGAASSAIFLYGSSLLYglsggstqlsaialalITSPSLGL--ALALVFVIAGIAFKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 107 MEGLSWMNCLVLMTWQKIAPFMLIsyVIFMNT------------FLSMVVMSsIIIGSLGGLNQTSLRKIMAYSSINHSG 174
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKAAGFALA--IRLLVTafpsfdeqwkllFTALAILS-MVLGNVVALAQTSMKRMLAYSSIGQAG 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 175 WMLAALTAGE----TYWLFYFGVYSFLStslVALFQASQLFYI--------NQTFLMKLPPSMKFWLFFLLLSLGGVPPF 242
Cdd:PRK02504  314 FVMIGLVAGTeagyASMVFYLLAYLFMN---LGAFACVILFSLrtgtdqisDYAGLYQKDPLLTLGLSLCLLSLGGIPPL 390

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1047475633 243 MGFMPK----WLVIQSLASLehifLLTVMVITTLLTLFYYLR 280
Cdd:PRK02504  391 AGFFGKiylfWAGWQAGLYL----LVLVGLVTSVISIYYYIR 428
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
148-286 2.81e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 51.49  E-value: 2.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 148 IIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALT----AGETYWLFYFGVYSFLSTSLvaLFQASQLFYINQTF------ 217
Cdd:PRK12663  283 MVIGALGALAYKDIRRIAGYQVISSIGFILLGLAlgtpAGINGAIFYLVHDMVVKTAL--FLIAGSLVRLTGYRslqylg 360

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 218 -LMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSF 286
Cdd:PRK12663  361 gLYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYSLFRIFFLAY 430
ndhB CHL00049
NADH dehydrogenase subunit 2
 39-281 3.63e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 48.08  E-value: 3.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  39 KNTMSTEAALKYFLIQALASSIFLFTVILMH-----------------FNNMTLLLNQPLFLTLLSSSLLLKMGAAPFHF 101
Cdd:CHL00049  156 KDVRSNEATMKYLLMGGASSSILVYGFSWLYglsggeielqeivngliNTQMYNSPGISIALIFITVGIGFKLSLAPFHQ 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 102 WFPGTMEGLSWMNCLVLMTWQKIAPFML---ISYVIF------MNTFLSMVVMSSIIIGSLGGLNQTSLRKIMAYSSINH 172
Cdd:CHL00049  236 WTPDVYEGSPTPVVAFLSVTSKVAASALatrIFDIPFyfssneWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQ 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 173 SGWMLAALTAGE---------TYWLFYfgvysfLSTSLVAlFQASQLFYI--------NQTFLMKLPPSMKFWLFFLLLS 235
Cdd:CHL00049  316 IGYVIIGIIVGDsndgyasmiTYMLFY------IFMNLGT-FACIVLFGLrtgtdnirDYAGLYTKDPFLALSLALCLLS 388

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1047475633 236 LGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRL 281
Cdd:CHL00049  389 LGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12650 PRK12650
DUF4040 family protein;
98-286 3.93e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 45.42  E-value: 3.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  98 PFHFWFPGTMEGLSWMNC-LVLMTWQKIAPFMLISYVIFM------NTFLSMVVMSSIIIGSLGGLNQTSLRKIMAYSSI 170
Cdd:PRK12650  226 PFHFWLPEAMAAITPVSAfLHAAAVVKAGIYLLLRFSPVFhdvavwNWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 171 NHSGWMLAALTAGETYWLFYFGVYsflsTSLVALFQASqLFYI-----NQT---------FLMKLPPSMKFWLFFLLLSL 236
Cdd:PRK12650  306 SQLGWIVATIGVGTPFALTAAVVH----TLAHALFKSS-LFMLigvvdHQAgtrdirrlgSLWRRMPFTFVSVTIAALSM 380

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1047475633 237 GGVPPFMGFMPKWLVIQSLASLE-----HIFLLTVMVITTLLTLFYYLRLAFTSF 286
Cdd:PRK12650  381 AAVPPLFGFVSKEGMLTAFLEAPggnagVVLLLVGAALGAVFTFAYSARLVLGAF 435
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 147-286 4.00e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 44.96  E-value: 4.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 147 SIIIGSLGGLNQTSLRKIMAYSSINHSGWMLAALTAGETYWLFYFGVYsFLSTSLVA--LFQASQLFY-------INQTF 217
Cdd:PRK12667  305 SAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFH-IINHAIAKslLFLASGVFIhaagtrdIDELA 383

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 218 LM-KLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLRLAFTSF 286
Cdd:PRK12667  384 GLgRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSLF 453
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-280 7.34e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 41.14  E-value: 7.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  34 LMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMTL--------LLNQPLFLTLLSSSLL------LKMGAAPF 99
Cdd:PRK08668  136 MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFdfadisqgLINDTSTGFALIVFLFllafgvAKAGIFPL 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 100 HFWFPGTME------------GLSWMNCL-------VLMTWQKIAPFMLISYVIFMNTFLSMVVMSSIIIGSLGGLNQTS 160
Cdd:PRK08668  216 HVWAPDAYSeapqsfsavlsgQLSKLGAYgfllvlyVLPGTKLFSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQED 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 161 LRKIMAYSSINHSGWMLAAL-------TAGETYWLFYFGVYS---FLSTSLVALFQASQLFYINQTFLMKLPPSMkFWLF 230
Cdd:PRK08668  296 IKKLIAYSSVANGGYILVGLglgtslgFAGGLFHVFNHALFKglfFLIFAAVIYRTGTTKISEMGGLIEKMPFTF-AMYL 374

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475633 231 FLLLSLGGVPPFMGFMPKWLVIQSLASLEHIFLLTVMVITTLLTLFYYLR 280
Cdd:PRK08668  375 VAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFR 424
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 238-286 1.03e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 40.52  E-value: 1.03e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1047475633 238 GVPPFMGFMPKWLVIQSL--ASLEHIFLLTVMVITTLLTLFYYLRLAFTSF 286
Cdd:COG1009   382 GIPPFAGFFSKEAILEAAleAGGLGPLLLAVALLGAFLTAFYSFRLFFLVF 432
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 2-300 2.61e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 39.41  E-value: 2.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633   2 ITLLSGTLISVSApTWFTSWMGLEINLLSFIPLMINTKNTMSTEAALKYFLIQALASSIFLFTVILMHFNNMTLL----- 76
Cdd:PRK06589  124 LTILIGVLIALSS-DLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVILIYTKTGNLdfvsg 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633  77 ----LNQPLFLTLLSSSLLLKMGAAPFHFWFPGTMEGLSWMNCL---VLMTWQKIAPFMLISYVIF----------MNTF 139
Cdd:PRK06589  203 glfsKNQSIILLLMFIYGIAKTAIFPVHSWLPAAMVAHYPVSALlhaVIVVKTGLFCIYKILLYIFglsylqrifaEFNW 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 140 LSMVVMSSIIIGSLGGLNQTSLRKIMAYSSINH------SGWMLAALTAGETywLFYFGVYSF-------LSTSLVALFQ 206
Cdd:PRK06589  283 LIFIPIVSIFYSSLKALKTDNIKKILAYSTISQlslallSAFILTPKALGAA--ILHLVSHSFakiclfySMGSIYSLKK 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 207 ASQLFYINQTFlmKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQSLASLEH----IFLLTVMVITTLLTLFYYLRLA 282
Cdd:PRK06589  361 EDQVDKLHGTS--KSFPLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQpwlsIIVMLVVIASSILSALYLLKIL 438

                         330
                  ....*....|....*...
gi 1047475633 283 FTSFSLSWQEISWFEISP 300
Cdd:PRK06589  439 SSIYKPSLSENSFITKSL 456
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 136-276 7.16e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 38.03  E-value: 7.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475633 136 MNTFLSMVVMSSIIIGSLGGLNQTSLRKIMAYSSINHSGWML--------AALTAGETYWLFYFGVYS--FLSTSLVALf 205
Cdd:PRK12665  272 LDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHIGYMVfgialstvAGLSGAIYYVAHHITVQTtlFLVVGLIER- 350

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1047475633 206 QASQLFYINQTFLMKLPPSMKFWLFFLLLSLGGVPPFMGFMPKWLVIQS---LASLEHIFLLTVMVITTLLTLF 276
Cdd:PRK12665  351 QAGSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSGFIGKVALLEAgaeDGTWLAWALVAGGVVTSLLTLY 424
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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