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Conserved domains on  [gi|1047475613|gb|ANW46911|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Isophya amplipennis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-310 2.04e-77

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 239.73  E-value: 2.04e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTlltNQT 80
Cdd:MTH00160   11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLML---FNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  81 LFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNtFISMVVVSSIFIGSLGGLTQTS 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 161 LRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQ-NFLMKQPPSVKFWLFFLLLSLGGV 239
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQlFNSNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1047475613 240 PPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFSLYWQEISWFEISPKNSPSHLMLM 310
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-310 2.04e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 239.73  E-value: 2.04e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTlltNQT 80
Cdd:MTH00160   11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLML---FNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  81 LFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNtFISMVVVSSIFIGSLGGLTQTS 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 161 LRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQ-NFLMKQPPSVKFWLFFLLLSLGGV 239
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQlFNSNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1047475613 240 PPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFSLYWQEISWFEISPKNSPSHLMLM 310
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 14-271 2.21e-33

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 124.35  E-value: 2.21e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  14 APTWLASWMGLEINLLSFIPLM-INTKNTLSTEAALKYFLIQALASSIFLFSVILMH--------------FNNMTLLTN 78
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYnytgtlsfdelskaLTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPLLLKMGAAPFHFWFPGTMEGLSW-VNCLVLMTWQKIAPFMLI-------SYVIVMNTFISMVVVSSIFI 150
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 151 GSLGGLTQTSLRKIMAYSSINHSGWMLAALTTGENY----WLFYFSIYMFLSSSIVILFQSFQL------YHINQNFLMK 220
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAGSVIYrrvhtrNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1047475613 221 QPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITT 271
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-281 1.68e-26

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 108.67  E-value: 1.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   7 GTIISVSAPTWLASWMGLEINLLSFIPL-MINTKNTLSTEAALKYFLIQALASSIFLFSVIL-------MHFNNMTLLTN 78
Cdd:COG1007   114 GMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatgsLNLAGIAAALA 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPLLL--------KMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPF---------MLISYVIVMNTFIS 141
Cdd:COG1007   194 AGGANSPLLLLGLVlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveAFPGLAADWQLLLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 142 MVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTG--ENYW--LFYFSIYMFLSS---SIVILF--QSFQLYH 212
Cdd:COG1007   274 VLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGtpLGVSaaLFYLLAYLFMNLgafAVILLLsrKGGEAEE 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 213 INQ-NFLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:COG1007   354 IEDlAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 5-281 1.95e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 94.24  E-value: 1.95e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   5 ISGTIISVSAPTWLASWMGLEINLLSFIPLM-INTKNTLSTEAALKYFLIQALASSIFLFSVILM-------HFNNMTLL 76
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  77 TNQTLFLALLSSP--------LLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPF------MLISYVIVMNTFISM 142
Cdd:TIGR01770 192 LSNGMLNISLLLLgivlilvgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFavflrlFLYILFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 143 V---VVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTT----GENYWLFYFSIYMFLSS---SIVILFQSFQLYH 212
Cdd:TIGR01770 272 LaiiAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtleGIKAVLFYIFIYALMSLgafGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1047475613 213 INQ----NFLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:TIGR01770 352 IEYisdfAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-310 2.04e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 239.73  E-value: 2.04e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTlltNQT 80
Cdd:MTH00160   11 LSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLML---FNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  81 LFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNtFISMVVVSSIFIGSLGGLTQTS 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN-FIIIIIILSAIIGAIGGLNQTS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 161 LRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQ-NFLMKQPPSVKFWLFFLLLSLGGV 239
Cdd:MTH00160  167 LRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQlFNSNNKSKKIKFLLFLNLLSLGGL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1047475613 240 PPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFSLYWQEISWFEISPKNSPSHLMLM 310
Cdd:MTH00160  247 PPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNF 317
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-285 1.20e-59

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 194.29  E-value: 1.20e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVI--LMHFN--NMTLL 76
Cdd:MTH00105   10 YLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIinLMYSGqwTITKL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  77 TNQTlFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFML---ISYVIVMNTFISMvVVSSIFIGSL 153
Cdd:MTH00105   90 TNPT-ASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSIlyqISPSINPNLLLTL-AILSILIGGW 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 154 GGLTQTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLM-KQPPSVKFWLFFL 232
Cdd:MTH00105  168 GGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTwNKTPLMTSLILLT 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1047475613 233 LLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTT 285
Cdd:MTH00105  248 LLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYST 300
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-303 1.67e-58

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 191.30  E-value: 1.67e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTLLTNQT 80
Cdd:MTH00041   10 ITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  81 LFLALLSSPL---LLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVI--VMNTFISMVVVSSIFIGSLGG 155
Cdd:MTH00041   90 LNTLSSIIITlalALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISnlLNSNILILCGILSVLVGGWGG 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 156 LTQTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHI-NQNFLMKQPPSVKFWLFFLLL 234
Cdd:MTH00041  170 LNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLsHLNKLSQLNPISAFLFILSIL 249

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1047475613 235 SLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFSLYWQEISWFEISPKNS 303
Cdd:MTH00041  250 SLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNS 318
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-285 1.12e-56

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 186.67  E-value: 1.12e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVIL--MHFNNMTLLTN 78
Cdd:MTH00070   10 LSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTInaWFTGEWTIMNM 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSP-LLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFML---ISYVIVMNTFISMVVVsSIFIGSLG 154
Cdd:MTH00070   90 QTPLPTIMLTIaLMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALliqISHLLNSNLLIIMGLL-STLIGGWG 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 155 GLTQTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFL--MKQPPsVKFWLFFL 232
Cdd:MTH00070  169 GLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSswSKNPT-LTSMMMLT 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1047475613 233 LLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTT 285
Cdd:MTH00070  248 LLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAM 300
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-285 1.35e-56

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 186.57  E-value: 1.35e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFN----NMTLL 76
Cdd:MTH00112   10 TTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNtgqwDITQL 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  77 TNQTlFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPF--MLISYVIVMNTFISMVVVSSIFIGSLG 154
Cdd:MTH00112   90 TNPT-SCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLtlLLMTSNSLNPTLLLTLAILSTLIGGWG 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 155 GLTQTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLM-KQPPSVKFWLFFLL 233
Cdd:MTH00112  169 GLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSwTKSPTLNTTLMLTL 248

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1047475613 234 LSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTT 285
Cdd:MTH00112  249 LSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYIS 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-287 6.01e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 173.92  E-value: 6.01e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTLLtnqt 80
Cdd:MTH00144   10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF---- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  81 lFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNTFISMVVVSSIF---IGSLGGLT 157
Cdd:MTH00144   86 -SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLsalVGSIGGLN 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 158 QTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLMKQPPSVKFWLFFLLLSLG 237
Cdd:MTH00144  165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLG 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475613 238 GVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFS 287
Cdd:MTH00144  245 GLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-284 1.39e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 173.45  E-value: 1.39e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLIS----GTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVI---------- 66
Cdd:MTH00135    6 LTILLFslglGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTtnawltgqwd 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  67 ---LMHFNNMTLLTnqtlflallsSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMN-TFISM 142
Cdd:MTH00135   86 iqqMSHPLPTTMIT----------LALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNpTLLIT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 143 VVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLM-KQ 221
Cdd:MTH00135  156 LGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSwTK 235

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1047475613 222 PPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFT 284
Cdd:MTH00135  236 APALTALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYA 298
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 1-314 2.18e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 172.16  E-value: 2.18e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   1 LTTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTlltnQT 80
Cdd:MTH00197    4 LFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYL----SL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  81 LFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNTFISMVVVSSIFIGSLGGLTQTS 160
Cdd:MTH00197   80 LSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 161 LRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLMKQPPSV-KFWLFFLLLSLGGV 239
Cdd:MTH00197  160 IRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSnLVFLGLSFLSLGGL 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1047475613 240 PPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFSL-YWQEISWFEISPKNSPSHLMLMVLST 314
Cdd:MTH00197  240 PPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILsNWMINFLMKINLLYSGLFILLMMMLP 315
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 3-285 4.36e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 172.08  E-value: 4.36e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   3 TLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTLLTNQTLF 82
Cdd:MTH00200   12 SLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLG 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  83 LALLSSPL---LLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLIS--YVIVMNTFISMVVVSSIFIGSLGGLT 157
Cdd:MTH00200   92 PLSETLILlalALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIqlAPALNSNILLLLGLLSVLVGGWGGLN 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 158 QTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLMK-QPPSVKFWLFFLLLSL 236
Cdd:MTH00200  172 QTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKtKNPILSMLLGLTLLSL 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1047475613 237 GGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTT 285
Cdd:MTH00200  252 GGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLT 300
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 2-288 2.48e-50

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 169.96  E-value: 2.48e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   2 TTLISGTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTLltnQTL 81
Cdd:MTH00011   13 STMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLL---KNI 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  82 FLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMN--TFISMVVVSSIFIGSLGGLTQT 159
Cdd:MTH00011   90 TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNilPMMTSMAAMSALAGGLGGMNQT 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 160 SLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYMFLSSSIVILFQSFQLYHINQNFLMKQ-PPSVKFWLFFLLLSLGG 238
Cdd:MTH00011  170 QLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSmSQTTSMSLFIMLLSLGG 249

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475613 239 VPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTFSL 288
Cdd:MTH00011  250 LPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYL 299
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 14-271 2.21e-33

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 124.35  E-value: 2.21e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  14 APTWLASWMGLEINLLSFIPLM-INTKNTLSTEAALKYFLIQALASSIFLFSVILMH--------------FNNMTLLTN 78
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYnytgtlsfdelskaLTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPLLLKMGAAPFHFWFPGTMEGLSW-VNCLVLMTWQKIAPFMLI-------SYVIVMNTFISMVVVSSIFI 150
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLIrrsllylPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 151 GSLGGLTQTSLRKIMAYSSINHSGWMLAALTTGENY----WLFYFSIYMFLSSSIVILFQSFQL------YHINQNFLMK 220
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIYgiqaAIFHLLTHGLFSAGLFLCAGSVIYrrvhtrNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1047475613 221 QPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITT 271
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-281 1.68e-26

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 108.67  E-value: 1.68e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   7 GTIISVSAPTWLASWMGLEINLLSFIPL-MINTKNTLSTEAALKYFLIQALASSIFLFSVIL-------MHFNNMTLLTN 78
Cdd:COG1007   114 GMMLMASANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatgsLNLAGIAAALA 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPLLL--------KMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPF---------MLISYVIVMNTFIS 141
Cdd:COG1007   194 AGGANSPLLLLGLVlvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFaallrllveAFPGLAADWQLLLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 142 MVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTG--ENYW--LFYFSIYMFLSS---SIVILF--QSFQLYH 212
Cdd:COG1007   274 VLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGtpLGVSaaLFYLLAYLFMNLgafAVILLLsrKGGEAEE 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 213 INQ-NFLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:COG1007   354 IEDlAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
7-281 1.81e-25

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 105.67  E-value: 1.81e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   7 GTIISVSAPTWLASWMGLEI-NLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVIL-------MHFNNMTLLTN 78
Cdd:PRK05777  115 GMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLlygatgsLSFAGIAKALA 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPLLL--------KMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLI---------SYVIVMNTFIS 141
Cdd:PRK05777  195 DGSGNSLLLLFGLVfllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvafgGLSEDWQQVLA 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 142 MVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTGENY----WLFYFSIYMF--LSSSIVIL------FQSFQ 209
Cdd:PRK05777  275 IIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFmtLGAFGVISllrrkgGEAES 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1047475613 210 LYHINQnfLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:PRK05777  355 ISDFAG--LSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 7-281 3.73e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 102.02  E-value: 3.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   7 GTIISVSAPTWLASWMGLEINLLS-FIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMH-------FNNMTLLTN 78
Cdd:MTH00199  109 GSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYgltgetsIQGINSILT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNTFISMVVVSSIFIGSLGGLTQ 158
Cdd:MTH00199  189 GDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVLSIIYGAIGALNQ 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 159 TSLRKIMAYSSINHSGWMLAALTTGEN----YWLFYFSIYMFLSSSIVILFQSFQLYH---INQNFLMKQPPSVKFWLFF 231
Cdd:MTH00199  269 TKIKRLLAYSGIGHMGFILFGVAIGSFesiqASLIYMIIYVIMSICSFSIILSLKLTKgliVEVSGLSRKNPVIALTLAL 348

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475613 232 LLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:MTH00199  349 TFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 7-301 5.30e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 100.49  E-value: 5.30e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   7 GTIISVSAPTWLASWMGLEINLLSFIPLMINTKNTL-STEAALKYFLIQALASSIFLFSVILM-------HFNNMTLLTN 78
Cdd:MTH00196    5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSGySAEAGLKYFVLGALSSGLFLFGCALLcgttgglHLSYINLVLN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  79 QTLFLALLSSPL---------LLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNTFISMVVVSSIF 149
Cdd:MTH00196   85 SGQSFSSVSVPIgylliivalLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSLF 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 150 IGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTGE----NYWLFYFSIYMFLSS---SIVILFQSFQLYHINQNFLMKQP 222
Cdd:MTH00196  165 VGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSIcvfSIILALNVYKNLIIEFSGLSRRL 244

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1047475613 223 PSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLsftTFSLYWQEISWFEISPK 301
Cdd:MTH00196  245 PILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI---VKILFFQANSFLLISTK 320
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 5-281 1.95e-21

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 94.24  E-value: 1.95e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   5 ISGTIISVSAPTWLASWMGLEINLLSFIPLM-INTKNTLSTEAALKYFLIQALASSIFLFSVILM-------HFNNMTLL 76
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIygftgslNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  77 TNQTLFLALLSSP--------LLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPF------MLISYVIVMNTFISM 142
Cdd:TIGR01770 192 LSNGMLNISLLLLgivlilvgLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFavflrlFLYILFGFSEAWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 143 V---VVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTT----GENYWLFYFSIYMFLSS---SIVILFQSFQLYH 212
Cdd:TIGR01770 272 LaiiAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtleGIKAVLFYIFIYALMSLgafGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1047475613 213 INQ----NFLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:TIGR01770 352 IEYisdfAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 21-281 6.43e-19

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 86.35  E-value: 6.43e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  21 WMGLEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFN----NMTLLTNQTLFLALLSSPLLL---- 92
Cdd:COG0651   133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGAtgtlNMADLAARLAELDPGLLLAAFalll 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  93 -----KMGAAPFHFWFPGTM-EGLSWVNCLV--LMTwqKIAPFMLISYVIVM-----NTFISMVVVS----SIFIGSLGG 155
Cdd:COG0651   213 vgfgiKAALFPLHFWLPDAYpAAPSPVSALLsgLLT--KVGVYAILRVLTLLfgadpALFLGTLLLVlgllTMLVGALGA 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 156 LTQTSLRKIMAYSSINHSGWMLAALTTGeNYWLFYFSIYMFLSSSIV--ILF----------QSFQLYHINQnfLMKQPP 223
Cdd:COG0651   291 LAQRDLKRLLAYSSVSQIGYILLGLGLG-TPLGLAGALFHLLNHALAkaLLFlaagaieratGTRDLDKLGG--LGKRMP 367

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1047475613 224 SVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:COG0651   368 LTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 24-312 1.77e-15

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 76.46  E-value: 1.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  24 LEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFN----NMTLLTNQ-------TLFLALLSSPLLL 92
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVtgtlNMADLAGAlaenptvVTAFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  93 KMGAAPFHFWFPGTM-EGLSWVNCLVLMTWQKIAPFMLI-----------SYVIVMNTFISMVVVSSIFIGSLGGLTQTS 160
Cdd:PRK08375  215 KAAVFPLHTWLPRAYpAAPPVVTALLSGLVTKVAVYALIriyftvfggdfRFALGLGWLLAVLALLSMLVGSLAALGQDD 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 161 LRKIMAYSSINHSGWML--------AALTTGenywLFYFSIYMFLSSSIVILFQSFQL-YHINQ----NFLMKQPPSVKF 227
Cdd:PRK08375  295 VKRVLAYSTVSQMGYILlglalltpLALAAG----LLHLLHHALMKGALFLAAGAIEVtYGTRRlselSGLGRRMPLTAA 370

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 228 WLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTtfsLYWQEISWFEISPKNSPSHL 307
Cdd:PRK08375  371 AFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYR---AFFGPPPPGSEAPKQEAPLG 447


                  ....*
gi 1047475613 308 MLMVL 312
Cdd:PRK08375  448 MLAPS 452
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 7-286 1.37e-10

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 62.18  E-value: 1.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613   7 GTIISVSAPTWLASWMGLEINLLSFIPL---------MINTKNTLSTEAALKYFLIQALASSIFLFSVILMH-------- 69
Cdd:MTH00198  200 GGLLLIESANWLTIYLALEFQTLALFILagegsqpgsHFPSPGNTPPESGLKYWILGAMSSGFYLFGCALYFgftgnegm 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  70 ---FNNMTLLTNQ------TLFLALLSSPLLLKMGAAPFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLISYVIVMNTFI 140
Cdd:MTH00198  280 lgtILSATLETTNielrqgSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSKLL 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 141 SMVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTG-----ENYWLfYFSIYM---FLSSSIVILFQSFQLYH 212
Cdd:MTH00198  360 LSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGtyeslQASWT-YAVTYLvsaLASFTVICTLEEFGTRT 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 213 INQ-------------------NFLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVN-------SGHLFMITI 266
Cdd:MTH00198  439 PTSrqrdgsfgnynlvrrlvdlTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVGSIKiafssslSIYYLVALF 518

                         330       340
                  ....*....|....*....|
gi 1047475613 267 MVITTLLTLFYYLRLSFTTF 286
Cdd:MTH00198  519 AIICTCISAFYYIRIVATIY 538
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
43-280 3.34e-10

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 60.84  E-value: 3.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  43 STEAALKYFLIQALASSIFLFSVILMHFNN----------MTLLTNQTLFLALLSSPLLL----KMGAAPFHFWFPGTME 108
Cdd:PRK02504  159 SNEAALKYLLIGAASSAIFLYGSSLLYGLSggstqlsaiaLALITSPSLGLALALVFVIAgiafKISAVPFHQWTPDVYE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 109 GLSWVNCLVLMTWQKIAPFMLISYVIVM---------NTFISMVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAA 179
Cdd:PRK02504  239 GSPTPVVAFLSVGSKAAGFALAIRLLVTafpsfdeqwKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIG 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 180 LTTG--ENY--WLFYFSIYMFL---SSSIVILFQ----SFQLYHINQnfLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPK 248
Cdd:PRK02504  319 LVAGteAGYasMVFYLLAYLFMnlgAFACVILFSlrtgTDQISDYAG--LYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1047475613 249 WLTIQSLVNSGHLFMITIMVITTLLTLFYYLR 280
Cdd:PRK02504  397 IYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
129-309 5.79e-09

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 56.88  E-value: 5.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 129 LISYVIVMNTFISMVvvssifIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTT-------GENYWLFYFSIYM----FL 197
Cdd:PRK12663  270 LLHPLLATMAAITMV------IGALGALAYKDIRRIAGYQVISSIGFILLGLALgtpaginGAIFYLVHDMVVKtalfLI 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 198 SSSIVILFQSFQLYHINQnfLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFY 277
Cdd:PRK12663  344 AGSLVRLTGYRSLQYLGG--LYRKEPLFGALFLILIFAIGGLPPFSGFWGKVLLVQGALDNGAYILLALMLITSLITMYS 421

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1047475613 278 YLRLSFTtfsLYWQEISWFEISPKNSPSHLML 309
Cdd:PRK12663  422 LFRIFFL---AYWGDKDGEEVNFKPIPLYRKL 450
ndhB CHL00049
NADH dehydrogenase subunit 2
 43-281 1.51e-08

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 55.78  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  43 STEAALKYFLIQALASSIFLFSVILMH-----------------FNNMTLLTNQTLFLALLSSPLLLKMGAAPFHFWFPG 105
Cdd:CHL00049  160 SNEATMKYLLMGGASSSILVYGFSWLYglsggeielqeivngliNTQMYNSPGISIALIFITVGIGFKLSLAPFHQWTPD 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 106 TMEGLSWVNCLVLMTWQKIAPFMLISYVIVM---------NTFISMVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWM 176
Cdd:CHL00049  240 VYEGSPTPVVAFLSVTSKVAASALATRIFDIpfyfssnewHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYV 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 177 LAALTTGEN---------YWLFYfsIYMFLSS-SIVILFQSFQLYHINQNF--LMKQPPSVKFWLFFLLLSLGGVPPFMG 244
Cdd:CHL00049  320 IIGIIVGDSndgyasmitYMLFY--IFMNLGTfACIVLFGLRTGTDNIRDYagLYTKDPFLALSLALCLLSLGGIPPLAG 397

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1047475613 245 FMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRL 281
Cdd:CHL00049  398 FFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 45-286 3.16e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 54.72  E-value: 3.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  45 EAALKYFLIQALASSIFLFSVILMHFN----NMTLLTNQTLFLALL---------SSPLLLKMGAAPFHFWFP-GTMEGL 110
Cdd:PRK08376  172 EAGIKYMFVGSLASSMVLLGIALLYGQygtlNMAYLAVKMSENPTVvakialalfIAGLAMKSGAVPVHMWLPdAYPAAP 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 111 SWVNCLVLMTWQ----KIAPFMLISYVIVMNT-----FISMVVVSSIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAAL- 180
Cdd:PRK08376  252 SSISAMLLVIKQaglyALARVLFSIYGPAINLatvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLGLg 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 181 ------------------TTGENYWLFYFSIY---MFLSSSIVIlfqsFQLYHINQN---FLMKQPPSVKFWLFFLLLSL 236
Cdd:PRK08376  332 vglaalgdpamasygeiaLAGGIYHIVNHALYkalLFLTAGAVI----YETGTRNLNelgGLARTMPKTTIAFLIGAAAI 407

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1047475613 237 GGVPPFMGFMPKWLTIQSlVNSGHLFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:PRK08376  408 VGLPPFNGFASKWLIYES-SALFNPILGVIAMIGSVLTLASFVKVFHTAF 456
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 147-286 1.06e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 49.97  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 147 SIFIGSLGGLTQTSLRKIMAYSSINHSGWMLAALTTGENYWLFYFSIYM----------FLSSSIVIlfQSFQLYHINQ- 215
Cdd:PRK12667  305 SAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksllFLASGVFI--HAAGTRDIDEl 382

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1047475613 216 NFLMKQPPSVKFWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:PRK12667  383 AGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSLF 453
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 98-286 2.19e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 49.00  E-value: 2.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  98 PFHFWFPGTMEGLSWVNCL------------VLMtwqKIAPfmLISYVIVMNTFISMVVVSSIFIGSLGGLTQTSLRKIM 165
Cdd:COG1009   229 PLHFWLPDAMEGPTPVSALlhaatmvkagvyLLA---RLSP--LFALSPVWLTVVAIIGAITALFAALIALAQTDIKRVL 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 166 AYSSINHSGWMLAALTTGeNYWLFYFSIY--------MFLSSSIVIlfqsfqLYHINQNF-----LMKQPPSVKFWLFFL 232
Cdd:COG1009   304 AYSTVSQLGYMFLALGVG-AYVAALFHLLthaffkalLFLGAGSVI------HATGTRDIrkmggLRKKMPITAITFLIG 376

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1047475613 233 LLSLGGVPPFMGFMPKWLTIQSLVNSG--HLFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:COG1009   377 ALSLAGIPPFAGFFSKEAILEAALEAGglGPLLLAVALLGAFLTAFYSFRLFFLVF 432
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
98-286 1.77e-05

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 46.17  E-value: 1.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  98 PFHFWFPGTMEGLSWVNCLVLMTWQKIAPFMLI-------SYVIVMNTFISMVVVSSIFIGSLGGLTQTSLRKIMAYSSI 170
Cdd:PRK07376  245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVarmypvfEQFPAVMTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 171 NHSGWMLAALTTGE-NYWLF------YFSIYMFLSSSIVI------------LFQSFQLyhinQNFLMKQPPSVKFWLFF 231
Cdd:PRK07376  325 SQLGYMVMAMGCGAySAGLFhlmthaYFKAMLFLGSGSVIhgmeevvghdpvLAQDMRL----MGGLRKYMPITAITFLI 400

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1047475613 232 LLLSLGGVPPFMGFMPKwLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:PRK07376  401 GCLAISGIPPFAGFWSK-DEILGAAFEANPALWFVGFLTAGMTAFYMFRMYFLTF 454
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-286 7.34e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 44.22  E-value: 7.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  34 LMINTKNTLSTEAALKYFLIQALASSIFLFSV--------------ILMHFNNMTLLTNQTLFLALLSSPLLLKMGAAPF 99
Cdd:PRK08668  136 MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIfliyaktgtfdfadISQGLINDTSTGFALIVFLFLLAFGVAKAGIFPL 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 100 HFWFPGTME------------GLS-------WVNCLVLMTWQKIAPFMLISYVIVMNTFISMVVVSSIFIGSLGGLTQTS 160
Cdd:PRK08668  216 HVWAPDAYSeapqsfsavlsgQLSklgaygfLLVLYVLPGTKLFSEFGTYRGVPLFNYILAWLGNISIIVGTLMAILQED 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 161 LRKIMAYSSINHSGWMLAALTTGENY----WLFY------FSIYMFLSSSIVILFQSFQLYHiNQNFLMKQPPSVKFWLF 230
Cdd:PRK08668  296 IKKLIAYSSVANGGYILVGLGLGTSLgfagGLFHvfnhalFKGLFFLIFAAVIYRTGTTKIS-EMGGLIEKMPFTFAMYL 374

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1047475613 231 FLLLSLGGVPPFMGFMPKWLTIQSLVNSGHLFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:PRK08668  375 VAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLAGVF 430
PRK12650 PRK12650
DUF4040 family protein;
98-286 5.58e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.57  E-value: 5.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  98 PFHFWFPGTMEGLSWVNC-LVLMTWQKIAPFMLISYVIVM------NTFISMVVVSSIFIGSLGGLTQTSLRKIMAYSSI 170
Cdd:PRK12650  226 PFHFWLPEAMAAITPVSAfLHAAAVVKAGIYLLLRFSPVFhdvavwNWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 171 NHSGWMLAALTTGENY------------WLFYFSIYMFLSssiVILFQSFQLYHINQNFLMKQPPSVKFWLFFLLLSLGG 238
Cdd:PRK12650  306 SQLGWIVATIGVGTPFaltaavvhtlahALFKSSLFMLIG---VVDHQAGTRDIRRLGSLWRRMPFTFVSVTIAALSMAA 382

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1047475613 239 VPPFMGFMPKWLTIQSLV-----NSGHLFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:PRK12650  383 VPPLFGFVSKEGMLTAFLeapggNAGVVLLLVGAALGAVFTFAYSARLVLGAF 435
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 24-286 7.44e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 37.87  E-value: 7.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  24 LEINLLSFIPLMINTKNTLSTEAALKYFLIQALASSIFLFSVILMHFNNMTLL---------TNQTLFLALLSSPLLLKM 94
Cdd:PRK06589  145 YELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAVILIYTKTGNLdfvsgglfsKNQSIILLLMFIYGIAKT 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  95 GAAPFHFWFPGTM-----------------EGLSWVNCLVLMTWQkiapFMLISYVIVMNTFISMVVVSSIFIGSLGGLT 157
Cdd:PRK06589  225 AIFPVHSWLPAAMvahypvsallhavivvkTGLFCIYKILLYIFG----LSYLQRIFAEFNWLIFIPIVSIFYSSLKALK 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 158 QTSLRKIMAYSSINH------SGWMLAALTTGENYWL-----FYFSIYMFLSSSIVILFQSFQLYHINQNFlmKQPPSVK 226
Cdd:PRK06589  301 TDNIKKILAYSTISQlslallSAFILTPKALGAAILHlvshsFAKICLFYSMGSIYSLKKEDQVDKLHGTS--KSFPLIS 378

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1047475613 227 FWLFFLLLSLGGVPPFMGFMPKWLTIQSLVNSGH----LFMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:PRK06589  379 FIISISSLSLIGIPIFSGFISKFLILLAASEQNQpwlsIIVMLVVIASSILSALYLLKILSSIY 442
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 99-286 8.73e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 37.75  E-value: 8.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613  99 FHFWFPGTMEGLSWVNCLV-LMTWQKIAPFMLI------SYVIVMNTFISMVVVSSIFIGSLGGLTQTSLRKIMAYSSIN 171
Cdd:MTH00020  229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrssplfEQAPLALIIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047475613 172 HSGWMLAALTTGE-NYWLF------YFSIYMFLSSSIVILFQSFQLYHINQNFLMKQPPSVKFWLFFLLLSLGGVPPFMG 244
Cdd:MTH00020  309 QLGYMVVACGLSHySISLFhlmnhaFFKALLFLSAGSVIHALSDEQDMRKMGGLISFLPLTYIFFLIGSLSLMGFPYLTG 388

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1047475613 245 FMPKWLTIQSLVNSGHL-FMITIMVITTLLTLFYYLRLSFTTF 286
Cdd:MTH00020  389 FYSKDLILELAFGQYYLiFAYWLGCFSALLTAFYSIRLIYLTF 431
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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