NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1039754792|ref|XP_017173216|]
View 

protein GPR108 isoform X1 [Mus musculus]

Protein Classification

lung seven transmembrane receptor family protein( domain architecture ID 10536224)

lung seven transmembrane receptor (LU7TM) family protein similar to mammalian orphan G-protein coupled receptor GPR107/108 and transmembrane protein 87A/B

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Lung_7-TM_R pfam06814
Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic ...
67-354 3.41e-110

Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.


:

Pssm-ID: 369089  Cd Length: 294  Bit Score: 324.66  E-value: 3.41e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792  67 EEGQYSLNFHNCHNSIPGQEQPFDLTVMIREKNPEGFLSAAEIPLFKLYLIMSACFLAADIFWVSVLCKNTYSVFKIHWL 146
Cdd:pfam06814   2 KTGLYCLYFHICDPKLSGSSSSLKLKVTVVWKNPYGYLSASEAPLMPFYGIMSLAYVLLGILWSFILFKYWHDILPIQKY 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792 147 MAALAFTKSVSLLFHSINYYFINSQGHPIEGLAVMHYITHLLKGALLFITIALIGSGWAFVKYMLSDKEKKIFGIVIPLQ 226
Cdd:pfam06814  82 IAAVIALGMAELAFHYIDYAFINSKGSSIEVLAVFASILSAAKKTLSRILLLIISLGYGIVKPTLGDTLSKVCGIGLLYF 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792 227 VLANVAYIVIESREEGASDYGLWKEILFLVDLicCGAILFPVVWSIRHLQDaSGTDGKVAVNLARLKLFRHYYVMVICYI 306
Cdd:pfam06814 162 VAACVLFIVRESGEEGDSSYKLWLVLFFLLPL--ALLDLFFVVWIFRSLQK-TLRDLRLRRNLVKLSLYRHFTNMLACSV 238
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039754792 307 YFTRIIAILLQVAV--------PFQWQWLYQLLVESSTLAFFVLTGYKFQPAGDNP 354
Cdd:pfam06814 239 VASFIIILVEKIYFvgtdmcnkYWKTLWLITAFWDLLTLVLLVVICYLWRPSQNNP 294
 
Name Accession Description Interval E-value
Lung_7-TM_R pfam06814
Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic ...
67-354 3.41e-110

Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.


Pssm-ID: 369089  Cd Length: 294  Bit Score: 324.66  E-value: 3.41e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792  67 EEGQYSLNFHNCHNSIPGQEQPFDLTVMIREKNPEGFLSAAEIPLFKLYLIMSACFLAADIFWVSVLCKNTYSVFKIHWL 146
Cdd:pfam06814   2 KTGLYCLYFHICDPKLSGSSSSLKLKVTVVWKNPYGYLSASEAPLMPFYGIMSLAYVLLGILWSFILFKYWHDILPIQKY 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792 147 MAALAFTKSVSLLFHSINYYFINSQGHPIEGLAVMHYITHLLKGALLFITIALIGSGWAFVKYMLSDKEKKIFGIVIPLQ 226
Cdd:pfam06814  82 IAAVIALGMAELAFHYIDYAFINSKGSSIEVLAVFASILSAAKKTLSRILLLIISLGYGIVKPTLGDTLSKVCGIGLLYF 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792 227 VLANVAYIVIESREEGASDYGLWKEILFLVDLicCGAILFPVVWSIRHLQDaSGTDGKVAVNLARLKLFRHYYVMVICYI 306
Cdd:pfam06814 162 VAACVLFIVRESGEEGDSSYKLWLVLFFLLPL--ALLDLFFVVWIFRSLQK-TLRDLRLRRNLVKLSLYRHFTNMLACSV 238
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039754792 307 YFTRIIAILLQVAV--------PFQWQWLYQLLVESSTLAFFVLTGYKFQPAGDNP 354
Cdd:pfam06814 239 VASFIIILVEKIYFvgtdmcnkYWKTLWLITAFWDLLTLVLLVVICYLWRPSQNNP 294
 
Name Accession Description Interval E-value
Lung_7-TM_R pfam06814
Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic ...
67-354 3.41e-110

Lung seven transmembrane receptor; This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.


Pssm-ID: 369089  Cd Length: 294  Bit Score: 324.66  E-value: 3.41e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792  67 EEGQYSLNFHNCHNSIPGQEQPFDLTVMIREKNPEGFLSAAEIPLFKLYLIMSACFLAADIFWVSVLCKNTYSVFKIHWL 146
Cdd:pfam06814   2 KTGLYCLYFHICDPKLSGSSSSLKLKVTVVWKNPYGYLSASEAPLMPFYGIMSLAYVLLGILWSFILFKYWHDILPIQKY 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792 147 MAALAFTKSVSLLFHSINYYFINSQGHPIEGLAVMHYITHLLKGALLFITIALIGSGWAFVKYMLSDKEKKIFGIVIPLQ 226
Cdd:pfam06814  82 IAAVIALGMAELAFHYIDYAFINSKGSSIEVLAVFASILSAAKKTLSRILLLIISLGYGIVKPTLGDTLSKVCGIGLLYF 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039754792 227 VLANVAYIVIESREEGASDYGLWKEILFLVDLicCGAILFPVVWSIRHLQDaSGTDGKVAVNLARLKLFRHYYVMVICYI 306
Cdd:pfam06814 162 VAACVLFIVRESGEEGDSSYKLWLVLFFLLPL--ALLDLFFVVWIFRSLQK-TLRDLRLRRNLVKLSLYRHFTNMLACSV 238
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039754792 307 YFTRIIAILLQVAV--------PFQWQWLYQLLVESSTLAFFVLTGYKFQPAGDNP 354
Cdd:pfam06814 239 VASFIIILVEKIYFvgtdmcnkYWKTLWLITAFWDLLTLVLLVVICYLWRPSQNNP 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH