|
Name |
Accession |
Description |
Interval |
E-value |
| VirB10 |
cd16429 |
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains ... |
1562-1758 |
1.87e-53 |
|
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.
:
Pssm-ID: 319755 Cd Length: 180 Bit Score: 185.40 E-value: 1.87e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1562 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVII 1640
Cdd:cd16429 1 LPAGTVIPAVLETAINSDLPGQVRAQVTRDVYDSTGRVLLIPKGSRLIGEYNSgVAQG---QSRVFVVWTRLITPDGVSI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1641 PLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkliglgkgrSERTPEFNYALGQAINGSMQS 1720
Cdd:cd16429 78 DLDSMPGADALGRAGLKGDVDNHFWERFGGALLLSLISDGAQAA---------------SSSASNSNSAGQAAGSNTGQS 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039411581 1721 SAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1758
Cdd:cd16429 143 LGQVASQILERNLNIPPTITIRQGTRINIFVARDLDFS 180
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
9-73 |
1.12e-29 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
:
Pssm-ID: 405299 Cd Length: 65 Bit Score: 112.81 E-value: 1.12e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039411581 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSE 73
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
139-195 |
4.90e-23 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
:
Pssm-ID: 405299 Cd Length: 65 Bit Score: 93.94 E-value: 4.90e-23
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1039411581 139 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 195
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 57
|
|
| PTZ00121 super family |
cl31754 |
MAEBL; Provisional |
716-1218 |
2.40e-14 |
|
MAEBL; Provisional
The actual alignment was detected with superfamily member PTZ00121:
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 79.41 E-value: 2.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 716 KTEAEKKECEKLLTPEARKLLEEAKKSVKayldcvsQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQAKNE 795
Cdd:PTZ00121 1219 KAEDAKKAEAVKKAEEAKKDAEEAKKAEE-------ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKK 1291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 796 AE--KKECEKLLTLESKKKLEEAKKS--VKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNA--KTEADKK 869
Cdd:PTZ00121 1292 ADeaKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEK 1371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 870 RCVKDLPKDLQKKVLAKESLKAykDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKAyldcvSQAKTEAEKKECEKL 949
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAK 1444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 950 LTPEARKLLEEAKESVKAYKDCVSKAR-NEKEKKECEKLLTPEAKKLLEQqvldclknAKTEADKKRCVKDLPKDLQKKV 1028
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKaDEAKKKAEEAKKADEAKKKAEE--------AKKKADEAKKAAEAKKKADEAK 1516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1029 LAKESVKAyldcvSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYK----DCLSQARNEEERRACEKLLTPEARKLLE 1104
Cdd:PTZ00121 1517 KAEEAKKA-----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeekKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1105 QEVKKSIKAYLDCVSRARNEKEKKECEKLLTPEARKFL-AKQVLNCLEKAGNEEERKAclKNLPKDLQENILAKESLKAY 1183
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKK 1669
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1039411581 1184 ----KDCLSQARNEEE----------RRACEKLLTPEARKLLEQEVKKS 1218
Cdd:PTZ00121 1670 aeedKKKAEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKA 1718
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
492-523 |
3.60e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
:
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.45 E-value: 3.60e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 492 AYKDCVSKARNEKEKQECEKLLTPEARKKLEQ 523
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
423-454 |
5.07e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
:
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.07 E-value: 5.07e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 423 EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQ 454
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
561-592 |
8.29e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
:
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.30 E-value: 8.29e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 561 AYKDCVSQAKTEAEKKECEKLLTPEAKKLLEE 592
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| SMC_N super family |
cl47134 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3-812 |
9.19e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
The actual alignment was detected with superfamily member pfam02463:
Pssm-ID: 481474 [Multi-domain] Cd Length: 1161 Bit Score: 44.19 E-value: 9.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 3 EENDKLETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDhhldnpTETQTHFDGDKSEETQTQMDSEGNETSessn 82
Cdd:pfam02463 223 EEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE------KLAQVLKENKEEEKEKKLQEEELKLLA---- 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 83 gSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSNEEATEANH 162
Cdd:pfam02463 293 -KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 163 FENLLKESKESSDH-----HLDNPTETQTNFDGDKSEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRsifhyf 237
Cdd:pfam02463 372 EEELLAKKKLESERlssaaKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGK------ 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 238 mpLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISN 317
Cdd:pfam02463 446 --LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGR 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 318 GGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKtdEERNE 397
Cdd:pfam02463 524 IISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAV--LEIDP 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 398 CLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEaEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIP 477
Cdd:pfam02463 602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK-ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 478 QDLQKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKE 557
Cdd:pfam02463 681 LQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKE 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 558 SLKAYKDCVSQAKTEAEKKEcekllTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVK 637
Cdd:pfam02463 761 EKEEEKSELSLKEKELAEER-----EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEL 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 638 AYLdcvsrARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKT 717
Cdd:pfam02463 836 EEL-----ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 718 EAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQAKNEAE 797
Cdd:pfam02463 911 LLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990
|
810
....*....|....*
gi 1039411581 798 KKECEKLLTLESKKK 812
Cdd:pfam02463 991 NKDELEKERLEEEKK 1005
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| VirB10 |
cd16429 |
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains ... |
1562-1758 |
1.87e-53 |
|
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.
Pssm-ID: 319755 Cd Length: 180 Bit Score: 185.40 E-value: 1.87e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1562 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVII 1640
Cdd:cd16429 1 LPAGTVIPAVLETAINSDLPGQVRAQVTRDVYDSTGRVLLIPKGSRLIGEYNSgVAQG---QSRVFVVWTRLITPDGVSI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1641 PLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkliglgkgrSERTPEFNYALGQAINGSMQS 1720
Cdd:cd16429 78 DLDSMPGADALGRAGLKGDVDNHFWERFGGALLLSLISDGAQAA---------------SSSASNSNSAGQAAGSNTGQS 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039411581 1721 SAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1758
Cdd:cd16429 143 LGQVASQILERNLNIPPTITIRQGTRINIFVARDLDFS 180
|
|
| T4SS_VirB10 |
NF038091 |
type IV secretion system protein VirB10; Members of this family are VirB10, an outer ... |
1556-1763 |
1.38e-49 |
|
type IV secretion system protein VirB10; Members of this family are VirB10, an outer membrane-associated protein from the apparatus of protein type IV secretion systems (T4SS). The model attempts to exclude related TraI proteins of conjugal transfer systems as well as the ComB10 protein of a DNA-translocating competence protein of Helicobacter pylori. Because the N-terminal regions of VirB10 proteins are highly variable, the model
Pssm-ID: 468345 Cd Length: 197 Bit Score: 175.06 E-value: 1.38e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1556 SDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAIT 1634
Cdd:NF038091 5 GDRDLLLTQGTMIPCVLETAIDSDLPGMVRCVVTRDVYSANGRVVLIERGSRVIGEYQSgLSQG---QARVFVLWTRIET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1635 PDGVIIPLANAqAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkligLGKGRSERTPEFNYalGQAI 1714
Cdd:NF038091 82 PDGVIVNLDSP-GTDELGRSGLPGYVDNHFWERFGGAILLSLIGDAGQYA----------ANKGQNGNGSGNGN--SVNF 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1039411581 1715 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDV 1763
Cdd:NF038091 149 ENTSQAASDMASEALENTINIPPTLYKNQGDRINIFVARDLDFSGVYEL 197
|
|
| VirB10 |
COG2948 |
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and ... |
1557-1761 |
1.43e-43 |
|
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442191 [Multi-domain] Cd Length: 309 Bit Score: 161.66 E-value: 1.43e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1557 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITP 1635
Cdd:COG2948 123 DSPYLLPAGTVIPAVLETGINSDLPGQITAQVTEDVYSATGRVLLIPQGSRLIGEYDSgVSFG---QSRVLVVWTRLITP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1636 DGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQtapiialdkligLGKGRSERTpefnyaLGQAI- 1714
Cdd:COG2948 200 DGVSIDLDSMPGTDALGRAGLEGQVDNHWWERFGAALLLSLLGDGAE------------LAASSDEGD------LSTAIr 261
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1039411581 1715 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1761
Cdd:COG2948 262 ENTAQSLSQAAQQILERNLNIPPTLTIRQGTRVRVIVARDLDFSSPY 308
|
|
| TrbI |
pfam03743 |
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI ... |
1561-1756 |
5.27e-42 |
|
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI protein greatly increase the conjugational efficiency.
Pssm-ID: 427480 Cd Length: 187 Bit Score: 152.81 E-value: 5.27e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1561 VLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWN-MNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGV 1638
Cdd:pfam03743 1 YLPAGTVIPAVLITGINSDLPGQVTAQVTEPVYDsATGRALLIPKGSRLIGEYGSgVAYG---QERVLVVWTRLICPDGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1639 IIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdklIGLGKGRSERTPEFNYALGQAINGSM 1718
Cdd:pfam03743 78 SIDLDSPGGVDALGRAGLRGRVDNHFGQRFGAALLLSLLGGGGELA--------NAASSNSTSTSTGNDNLLGAVGSGAG 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039411581 1719 QSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDID 1756
Cdd:pfam03743 150 QALSQLAQQILERALNIPPTITVRQGTRVRIIVNRDLD 187
|
|
| VirB10_subf |
NF041422 |
VirB10/TraB/TrbI family type IV secretion system protein; |
1557-1765 |
3.89e-30 |
|
VirB10/TraB/TrbI family type IV secretion system protein;
Pssm-ID: 469313 Cd Length: 404 Bit Score: 125.13 E-value: 3.89e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1557 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS--VKGGtpiMTRLMIVFTKAIT 1634
Cdd:NF041422 210 DPDLYIPENTYIPCSLDRRFVSDVAGKISCTISEDVYSASGHVKLIPKGTTARGVYKTgtLKHG---QGRMFIIWTELRT 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1635 PD--GVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPiialdkliGLGKGRSERTpefNYAlgq 1712
Cdd:NF041422 287 PEppYLDIPLVDTQAAGQLGEAGIDGWIDTHFWERFGNALMLSTVQDVAAAAS--------GSAPGKDRNT---DYT--- 352
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1039411581 1713 aiNGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKI 1765
Cdd:NF041422 353 --ENSRQATAEMAKTALENSINIPPTLYKNQGDIIGLITGQDIDFSSIYQLRM 403
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
9-73 |
1.12e-29 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 112.81 E-value: 1.12e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039411581 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSE 73
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| PRK13855 |
PRK13855 |
type IV secretion system protein VirB10; Provisional |
1558-1770 |
2.81e-29 |
|
type IV secretion system protein VirB10; Provisional
Pssm-ID: 172376 Cd Length: 376 Bit Score: 121.93 E-value: 2.81e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1558 PTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQsvKGGTPIMTRLMIVFTKAITPDG 1637
Cdd:PRK13855 178 PDFMVTQGTIIPCILQTAIDTNLAGYVKCVLPQDIRGTTNNVVLLDRGTTVVGEIQ--RGLQQGDARVFVLWDRAETPDH 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1638 VIIPLAnAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIAldkliglgkGRSERTPEFNyalgqaingS 1717
Cdd:PRK13855 256 AMISLS-SPGADELGRSGLPGTVDNHFWQRFSGAMLLSVVQGAFQAASTYA---------GSSGGGTSFN---------S 316
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1039411581 1718 MQSS-AQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSV 1770
Cdd:PRK13855 317 FQNNgEQTADTALKATINIPPTLKKNQGDTVSIFVARDLDFSGIYQLRMTGGAT 370
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
139-195 |
4.90e-23 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 93.94 E-value: 4.90e-23
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1039411581 139 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 195
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 57
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
716-1218 |
2.40e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 79.41 E-value: 2.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 716 KTEAEKKECEKLLTPEARKLLEEAKKSVKayldcvsQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQAKNE 795
Cdd:PTZ00121 1219 KAEDAKKAEAVKKAEEAKKDAEEAKKAEE-------ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKK 1291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 796 AE--KKECEKLLTLESKKKLEEAKKS--VKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNA--KTEADKK 869
Cdd:PTZ00121 1292 ADeaKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEK 1371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 870 RCVKDLPKDLQKKVLAKESLKAykDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKAyldcvSQAKTEAEKKECEKL 949
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAK 1444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 950 LTPEARKLLEEAKESVKAYKDCVSKAR-NEKEKKECEKLLTPEAKKLLEQqvldclknAKTEADKKRCVKDLPKDLQKKV 1028
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKaDEAKKKAEEAKKADEAKKKAEE--------AKKKADEAKKAAEAKKKADEAK 1516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1029 LAKESVKAyldcvSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYK----DCLSQARNEEERRACEKLLTPEARKLLE 1104
Cdd:PTZ00121 1517 KAEEAKKA-----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeekKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1105 QEVKKSIKAYLDCVSRARNEKEKKECEKLLTPEARKFL-AKQVLNCLEKAGNEEERKAclKNLPKDLQENILAKESLKAY 1183
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKK 1669
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1039411581 1184 ----KDCLSQARNEEE----------RRACEKLLTPEARKLLEQEVKKS 1218
Cdd:PTZ00121 1670 aeedKKKAEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKA 1718
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
660-840 |
7.59e-05 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 47.15 E-value: 7.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 660 TPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEA---RKLL 736
Cdd:TIGR02794 66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAeaeRKAK 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 737 EEAKKsvKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYldcVSQAKNEAEKKECEKlltlESKKKLEEA 816
Cdd:TIGR02794 146 EEAAK--QAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE---EAKAKAEAAKAKAAA----EAAAKAEAE 216
|
170 180
....*....|....*....|....
gi 1039411581 817 KKsvkayldcvSQAKTEAEKKECE 840
Cdd:TIGR02794 217 AA---------AAAAAEAERKADE 231
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1074-1105 |
1.58e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 40.61 E-value: 1.58e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 1074 AYKDCLSQARNEEERRACEKLLTPEARKLLEQ 1105
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
492-523 |
3.60e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.45 E-value: 3.60e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 492 AYKDCVSKARNEKEKQECEKLLTPEARKKLEQ 523
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
423-454 |
5.07e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.07 E-value: 5.07e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 423 EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQ 454
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
561-592 |
8.29e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.30 E-value: 8.29e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 561 AYKDCVSQAKTEAEKKECEKLLTPEAKKLLEE 592
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3-812 |
9.19e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.19 E-value: 9.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 3 EENDKLETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDhhldnpTETQTHFDGDKSEETQTQMDSEGNETSessn 82
Cdd:pfam02463 223 EEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE------KLAQVLKENKEEEKEKKLQEEELKLLA---- 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 83 gSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSNEEATEANH 162
Cdd:pfam02463 293 -KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 163 FENLLKESKESSDH-----HLDNPTETQTNFDGDKSEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRsifhyf 237
Cdd:pfam02463 372 EEELLAKKKLESERlssaaKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGK------ 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 238 mpLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISN 317
Cdd:pfam02463 446 --LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGR 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 318 GGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKtdEERNE 397
Cdd:pfam02463 524 IISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAV--LEIDP 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 398 CLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEaEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIP 477
Cdd:pfam02463 602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK-ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 478 QDLQKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKE 557
Cdd:pfam02463 681 LQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKE 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 558 SLKAYKDCVSQAKTEAEKKEcekllTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVK 637
Cdd:pfam02463 761 EKEEEKSELSLKEKELAEER-----EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEL 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 638 AYLdcvsrARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKT 717
Cdd:pfam02463 836 EEL-----ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 718 EAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQAKNEAE 797
Cdd:pfam02463 911 LLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990
|
810
....*....|....*
gi 1039411581 798 KKECEKLLTLESKKK 812
Cdd:pfam02463 991 NKDELEKERLEEEKK 1005
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
3-598 |
1.38e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 3 EENDKLETSKKAQQDSPQDLSNEEATEANHFENLLK---ESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSE 79
Cdd:PTZ00121 1287 EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKkaeEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 80 SSngslADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSNEEATE 159
Cdd:PTZ00121 1367 EA----AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 160 ANHFENLLKESKESSD-HHLDNPTEtqtnfDGDKSEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRsifhyfm 238
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKaEEAKKKAE-----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK------- 1510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 239 pledKSSRFSKDRNLYVNDEIQIRQEYNRllKERNEKGNMIDKNlffndDPNRTLYNYLNIAEIEDKNPLRAFYECISNG 318
Cdd:PTZ00121 1511 ----KADEAKKAEEAKKADEAKKAEEAKK--ADEAKKAEEKKKA-----DELKKAEELKKAEEKKKAEEAKKAEEDKNMA 1579
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 319 GNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNA-KTEEERIKCLDLIKDENLKKSLLNQQKvqvaldclknaKTDEERNE 397
Cdd:PTZ00121 1580 LRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAkKAEEAKIKAEELKKAEEEKKKVEQLKK-----------KEAEEKKK 1648
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 398 CLKLINDPEiREKFRKELELQKELQEYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQQALdclkNAKTDEERNEClknip 477
Cdd:PTZ00121 1649 AEELKKAEE-ENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL----KKKEAEEKKKA----- 1718
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 478 qdlqKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEA-RKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAK 556
Cdd:PTZ00121 1719 ----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEeKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1039411581 557 ESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESV 598
Cdd:PTZ00121 1795 EVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVA 1836
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| VirB10 |
cd16429 |
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains ... |
1562-1758 |
1.87e-53 |
|
VirB10 forms part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS), including homologs TrbI, TraF, TrwE and TraL. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both, the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TrwE in R33 plasmid has been shown to be anchored to the inner membrane and its C-terminal is necessary for conjugation; the transmembrane domains of TrwB and TrwE are involved in TrwB-TrwE interactions. TraF protein of the RP4 plasmid is involved in circularization of pilin subunits of P-type pili. In gonococcal genetic island (GGI) of Neisseria gonorrhoeae, T4SS encodes TrbI and circularization occurs via a covalent intermediate between the C terminus of putative pilin protein TraA and TrbI.
Pssm-ID: 319755 Cd Length: 180 Bit Score: 185.40 E-value: 1.87e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1562 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVII 1640
Cdd:cd16429 1 LPAGTVIPAVLETAINSDLPGQVRAQVTRDVYDSTGRVLLIPKGSRLIGEYNSgVAQG---QSRVFVVWTRLITPDGVSI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1641 PLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkliglgkgrSERTPEFNYALGQAINGSMQS 1720
Cdd:cd16429 78 DLDSMPGADALGRAGLKGDVDNHFWERFGGALLLSLISDGAQAA---------------SSSASNSNSAGQAAGSNTGQS 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039411581 1721 SAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1758
Cdd:cd16429 143 LGQVASQILERNLNIPPTITIRQGTRINIFVARDLDFS 180
|
|
| T4SS_VirB10 |
NF038091 |
type IV secretion system protein VirB10; Members of this family are VirB10, an outer ... |
1556-1763 |
1.38e-49 |
|
type IV secretion system protein VirB10; Members of this family are VirB10, an outer membrane-associated protein from the apparatus of protein type IV secretion systems (T4SS). The model attempts to exclude related TraI proteins of conjugal transfer systems as well as the ComB10 protein of a DNA-translocating competence protein of Helicobacter pylori. Because the N-terminal regions of VirB10 proteins are highly variable, the model
Pssm-ID: 468345 Cd Length: 197 Bit Score: 175.06 E-value: 1.38e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1556 SDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAIT 1634
Cdd:NF038091 5 GDRDLLLTQGTMIPCVLETAIDSDLPGMVRCVVTRDVYSANGRVVLIERGSRVIGEYQSgLSQG---QARVFVLWTRIET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1635 PDGVIIPLANAqAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdkligLGKGRSERTPEFNYalGQAI 1714
Cdd:NF038091 82 PDGVIVNLDSP-GTDELGRSGLPGYVDNHFWERFGGAILLSLIGDAGQYA----------ANKGQNGNGSGNGN--SVNF 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1039411581 1715 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDV 1763
Cdd:NF038091 149 ENTSQAASDMASEALENTINIPPTLYKNQGDRINIFVARDLDFSGVYEL 197
|
|
| VirB10 |
COG2948 |
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and ... |
1557-1761 |
1.43e-43 |
|
Type IV secretory pathway, VirB10 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442191 [Multi-domain] Cd Length: 309 Bit Score: 161.66 E-value: 1.43e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1557 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITP 1635
Cdd:COG2948 123 DSPYLLPAGTVIPAVLETGINSDLPGQITAQVTEDVYSATGRVLLIPQGSRLIGEYDSgVSFG---QSRVLVVWTRLITP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1636 DGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQtapiialdkligLGKGRSERTpefnyaLGQAI- 1714
Cdd:COG2948 200 DGVSIDLDSMPGTDALGRAGLEGQVDNHWWERFGAALLLSLLGDGAE------------LAASSDEGD------LSTAIr 261
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1039411581 1715 NGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1761
Cdd:COG2948 262 ENTAQSLSQAAQQILERNLNIPPTLTIRQGTRVRVIVARDLDFSSPY 308
|
|
| TrbI |
pfam03743 |
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI ... |
1561-1756 |
5.27e-42 |
|
Bacterial conjugation TrbI-like protein; Although not essential for conjugation, the TrbI protein greatly increase the conjugational efficiency.
Pssm-ID: 427480 Cd Length: 187 Bit Score: 152.81 E-value: 5.27e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1561 VLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWN-MNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGV 1638
Cdd:pfam03743 1 YLPAGTVIPAVLITGINSDLPGQVTAQVTEPVYDsATGRALLIPKGSRLIGEYGSgVAYG---QERVLVVWTRLICPDGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1639 IIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTApiialdklIGLGKGRSERTPEFNYALGQAINGSM 1718
Cdd:pfam03743 78 SIDLDSPGGVDALGRAGLRGRVDNHFGQRFGAALLLSLLGGGGELA--------NAASSNSTSTSTGNDNLLGAVGSGAG 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039411581 1719 QSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDID 1756
Cdd:pfam03743 150 QALSQLAQQILERALNIPPTITVRQGTRVRIIVNRDLD 187
|
|
| VirB10_like |
cd16426 |
VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS); This ... |
1562-1758 |
1.19e-35 |
|
VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS); This family contains VirB10, a component of the type IV secretion system (T4SS) and its homologs, including TraB, TraF, IcmE, and similar proteins. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10 interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. In Gram-negative bacterial pathogen Helicobacter pylori, an important aetiological agent of gastroduodenal disease in humans, the comB3 gene encodes protein with best homologies to TraS/TraB from the Pseudomonas aeruginosa conjugative plasmid RP1 and TrbI of plasmid RP4 and VirB10 from the Ti plasmid of Agrobacterium tumefaciens, as well as DotG/IcmE of Legionella pneumophila.
Pssm-ID: 319754 [Multi-domain] Cd Length: 151 Bit Score: 133.05 E-value: 1.19e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1562 LAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQsvkGGTPIMTRLMIVFTKAITPDGVIIP 1641
Cdd:cd16426 1 LLPGTIIPAVLLTGIDSDLPGPVLARVTRDVYDPNGGRLLIPKGSRLIGEYY---GDLSSQERVLVRWTRLICPDGVSID 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1642 LANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVnsflqtapiialdkliglgkgrsertpefnyalgqaingsmqsS 1721
Cdd:cd16426 78 LDSVAGADALGRAGLRGDVDNHFGERFGGALLASLL-------------------------------------------S 114
|
170 180 190
....*....|....*....|....*....|....*..
gi 1039411581 1722 AQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFS 1758
Cdd:cd16426 115 GQLAQQYLQRAENIPPTITVNAGTRVNIVVARDVDLP 151
|
|
| VirB10_subf |
NF041422 |
VirB10/TraB/TrbI family type IV secretion system protein; |
1557-1765 |
3.89e-30 |
|
VirB10/TraB/TrbI family type IV secretion system protein;
Pssm-ID: 469313 Cd Length: 404 Bit Score: 125.13 E-value: 3.89e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1557 DPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQS--VKGGtpiMTRLMIVFTKAIT 1634
Cdd:NF041422 210 DPDLYIPENTYIPCSLDRRFVSDVAGKISCTISEDVYSASGHVKLIPKGTTARGVYKTgtLKHG---QGRMFIIWTELRT 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1635 PD--GVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPiialdkliGLGKGRSERTpefNYAlgq 1712
Cdd:NF041422 287 PEppYLDIPLVDTQAAGQLGEAGIDGWIDTHFWERFGNALMLSTVQDVAAAAS--------GSAPGKDRNT---DYT--- 352
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1039411581 1713 aiNGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKI 1765
Cdd:NF041422 353 --ENSRQATAEMAKTALENSINIPPTLYKNQGDIIGLITGQDIDFSSIYQLRM 403
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
9-73 |
1.12e-29 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 112.81 E-value: 1.12e-29
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039411581 9 ETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSE 73
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEEITDDSNDQ 65
|
|
| PRK13855 |
PRK13855 |
type IV secretion system protein VirB10; Provisional |
1558-1770 |
2.81e-29 |
|
type IV secretion system protein VirB10; Provisional
Pssm-ID: 172376 Cd Length: 376 Bit Score: 121.93 E-value: 2.81e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1558 PTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQsvKGGTPIMTRLMIVFTKAITPDG 1637
Cdd:PRK13855 178 PDFMVTQGTIIPCILQTAIDTNLAGYVKCVLPQDIRGTTNNVVLLDRGTTVVGEIQ--RGLQQGDARVFVLWDRAETPDH 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1638 VIIPLAnAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIAldkliglgkGRSERTPEFNyalgqaingS 1717
Cdd:PRK13855 256 AMISLS-SPGADELGRSGLPGTVDNHFWQRFSGAMLLSVVQGAFQAASTYA---------GSSGGGTSFN---------S 316
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1039411581 1718 MQSS-AQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSV 1770
Cdd:PRK13855 317 FQNNgEQTADTALKATINIPPTLKKNQGDTVSIFVARDLDFSGIYQLRMTGGAT 370
|
|
| CagY_I |
pfam14585 |
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the ... |
139-195 |
4.90e-23 |
|
CagY type 1 repeat; This repeat is found at the N-terminus of the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells.
Pssm-ID: 405299 Cd Length: 65 Bit Score: 93.94 E-value: 4.90e-23
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1039411581 139 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 195
Cdd:pfam14585 1 ETSKKTQQHSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTNFDGDKSEE 57
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
716-1218 |
2.40e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 79.41 E-value: 2.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 716 KTEAEKKECEKLLTPEARKLLEEAKKSVKayldcvsQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQAKNE 795
Cdd:PTZ00121 1219 KAEDAKKAEAVKKAEEAKKDAEEAKKAEE-------ERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKK 1291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 796 AE--KKECEKLLTLESKKKLEEAKKS--VKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNA--KTEADKK 869
Cdd:PTZ00121 1292 ADeaKKAEEKKKADEAKKKAEEAKKAdeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAeeKAEAAEK 1371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 870 RCVKDLPKDLQKKVLAKESLKAykDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKAyldcvSQAKTEAEKKECEKL 949
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKA--DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKAEEAK 1444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 950 LTPEARKLLEEAKESVKAYKDCVSKAR-NEKEKKECEKLLTPEAKKLLEQqvldclknAKTEADKKRCVKDLPKDLQKKV 1028
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKaDEAKKKAEEAKKADEAKKKAEE--------AKKKADEAKKAAEAKKKADEAK 1516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1029 LAKESVKAyldcvSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYK----DCLSQARNEEERRACEKLLTPEARKLLE 1104
Cdd:PTZ00121 1517 KAEEAKKA-----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeekKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1105 QEVKKSIKAYLDCVSRARNEKEKKECEKLLTPEARKFL-AKQVLNCLEKAGNEEERKAclKNLPKDLQENILAKESLKAY 1183
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKK 1669
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1039411581 1184 ----KDCLSQARNEEE----------RRACEKLLTPEARKLLEQEVKKS 1218
Cdd:PTZ00121 1670 aeedKKKAEEAKKAEEdekkaaealkKEAEEAKKAEELKKKEAEEKKKA 1718
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
256-1027 |
7.85e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.49 E-value: 7.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 256 NDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECIsngGNYEECLKLIKDKKLQD 335
Cdd:PTZ00121 1038 NDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF---GKAEEAKKTETGKAEEA 1114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 336 QMKKtlEAYNDCIKNAKTEEERiKCLDLIKDENLKKSLlNQQKVQVALDCLKNAKTDEERN-ECLKLINDPEIREKFRKE 414
Cdd:PTZ00121 1115 RKAE--EAKKKAEDARKAEEAR-KAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKaEDAKKAEAARKAEEVRKA 1190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 415 LELQKELQ----EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNEclknipQDLQKELLADMSV 490
Cdd:PTZ00121 1191 EELRKAEDarkaEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNN------EEIRKFEEARMAH 1264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 491 KAYKDCVSKArneKEKQECEKLLTPEARKKLEQqvldclknAKTDEERKKcLKDLPKDLQSDILAKESLKAYKDCVSQAK 570
Cdd:PTZ00121 1265 FARRQAAIKA---EEARKADELKKAEEKKKADE--------AKKAEEKKK-ADEAKKKAEEAKKADEAKKKAEEAKKKAD 1332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 571 tEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQA--KTEAEKKECEKLltpEAKKKLEEAKKSVKAYLDCVSRARN 648
Cdd:PTZ00121 1333 -AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAekKKEEAKKKADAA---KKKAEEKKKADEAKKKAEEDKKKAD 1408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 649 EKEKKECEKLLTPEAKKLLEQQALdcLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAyldcvsqaKTEAEKKECEKLL 728
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEKKK--ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK--------AEEAKKADEAKKK 1478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 729 TPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQA---KNEAEKKECEKLL 805
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAeekKKADELKKAEELK 1558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 806 TLESKKKLEEAKKSVKAYLDCVSQAKteaEKKECEKLLTPEAKKLLEQQALDCLKNAKTEADKKRCVKDLPKDLQKKVLA 885
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKNMALRKAE---EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKV 1635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 886 KESLKAYKDCVSKARNEKEKKECEKLLTPEAKKLLEEAKKSVKayldcvSQAKTEAEKKECEKLLTPEARKlLEEAKESV 965
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE------EAKKAEEDEKKAAEALKKEAEE-AKKAEELK 1708
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039411581 966 KAYKDCVSKARNEKEKKECEKLLTPEAKKLLEQQVLDClKNAKTEADKKRCVKDLPKDLQKK 1027
Cdd:PTZ00121 1709 KKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA-EEAKKDEEEKKKIAHLKKEEEKK 1769
|
|
| PRK13881 |
PRK13881 |
conjugal transfer protein TrbI; Provisional |
1571-1761 |
1.16e-08 |
|
conjugal transfer protein TrbI; Provisional
Pssm-ID: 237541 Cd Length: 472 Bit Score: 59.79 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1571 TLTSKVDATLTGIVSGVVAKDVWNM-NGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMIVFTKAITPDGVIIPLANAQAA 1648
Cdd:PRK13881 288 TLISGINSDLPGQIMAQVSQNVYDTaTGKHLLIPQGSRLVGSYSSdVAYG---QARVLVAWQRIVFPDGKAMDIGAMPGA 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1649 GMLGEAGVDGYVNNHFMKRIGFAVIASVVnsflqTAPiialdklIGLGKGRSERTPEFNY-----ALGQAINgsmQSSAQ 1723
Cdd:PRK13881 365 DSAGYAGFRDQVNNHYVRIFGSAFLMSGV-----TAG-------ITYSQDQNQNNNGYGQptassALSEALG---QQLGQ 429
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039411581 1724 MSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1761
Cdd:PRK13881 430 VTAQLIAKNLNIAPTLEIRPGYRFNVIVTKDMTFSKPY 467
|
|
| IcmE |
cd16431 |
DotG/IcmE is a homolog of VirB10 which forms part of core complex in Type IV secretion system; ... |
1604-1755 |
1.87e-08 |
|
DotG/IcmE is a homolog of VirB10 which forms part of core complex in Type IV secretion system; This family contains DotG/IcmE (VirB10 homolog) and a component of the type IV secretion system (T4SS), and similar proteins. The Dot/Icm system is a T4SS found in the pathogens Legionella and Coxiella and the conjugative apparatus of IncI plasmids; T4SS is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. Similar to T4SS VirB/D components, the Legionella Dot/Icm secretion apparatus contains a critical five-protein sub-assembly that forms the membrane-spanning 'core-complex' (CC), around which all other components assemble. This transmembrane connection is mediated by protein dimer pairs consisting of two inner membrane proteins, DotF and DotG, each independently associating with DotH/DotC/DotD in the outer membrane.
Pssm-ID: 319757 Cd Length: 179 Bit Score: 56.05 E-value: 1.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1604 KGTKVYGNYQSVKggtpimTRLMIVFTKAITPDGVIIPLaNAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVV----NS 1679
Cdd:cd16431 34 KGARLIGSFERSG------DGVVITFTTMVLPGGKSYPI-DAYALDDRTLSAVASDVDNHYLSRYGLPAAAAFLqglgQA 106
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039411581 1680 FLQTAPIIAldkLIGLGKGRSER-TPEFNYALGQAINGSMQssaQMSnQILGQLMNIPPSFYKNEGDSIKILTMDDI 1755
Cdd:cd16431 107 YQQAGTTTT---STSGGTVTVTTgTPDGKQAAGAAAGGVGQ---QLG-QVLAQDANRPPTVTVPAGTPIGILFMSDV 176
|
|
| PRK13831 |
PRK13831 |
conjugal transfer protein TrbI; Provisional |
1558-1761 |
3.92e-07 |
|
conjugal transfer protein TrbI; Provisional
Pssm-ID: 172358 [Multi-domain] Cd Length: 432 Bit Score: 54.74 E-value: 3.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1558 PTFVLAQYTPIEITLTSKVDATL-TGIVSGV-------VAKDVWN-MNGTMILLDKGTKVYGNYQS-VKGGtpiMTRLMI 1627
Cdd:PRK13831 233 PNRVVPQQSPYELKRGSVIPATLiTGINSDLpgritaqVSQNVYDsATGHRLLIPQGTKLFGRYDSkVSFG---QSRVLV 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 1628 VFTKAITPDGviiplANAQAAGMlgeAGVD--GY------VNNHFMKRIGFAVIasvvnsflqtapiIALdklIGLGKGR 1699
Cdd:PRK13831 310 VWTDIIFPNG-----STLQIGGM---AGTDaeGYggfkdkVDRHYLRTFGSAIL-------------IAL---IGTGIDM 365
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039411581 1700 SerTPEFNYALGQ------AINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVY 1761
Cdd:PRK13831 366 A--VPESSTLATQdtasdaARRNFAETFGRVAERTISKNLNVQPTLEIRPGYKFNVLVDQDIVFPGAY 431
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
660-840 |
7.59e-05 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 47.15 E-value: 7.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 660 TPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEA---RKLL 736
Cdd:TIGR02794 66 EQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAeaeRKAK 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 737 EEAKKsvKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYldcVSQAKNEAEKKECEKlltlESKKKLEEA 816
Cdd:TIGR02794 146 EEAAK--QAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE---EAKAKAEAAKAKAAA----EAAAKAEAE 216
|
170 180
....*....|....*....|....
gi 1039411581 817 KKsvkayldcvSQAKTEAEKKECE 840
Cdd:TIGR02794 217 AA---------AAAAAEAERKADE 231
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1074-1105 |
1.58e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 40.61 E-value: 1.58e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 1074 AYKDCLSQARNEEERRACEKLLTPEARKLLEQ 1105
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1182-1213 |
1.58e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 40.61 E-value: 1.58e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 1182 AYKDCLSQARNEEERRACEKLLTPEARKLLEQ 1213
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
492-523 |
3.60e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.45 E-value: 3.60e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 492 AYKDCVSKARNEKEKQECEKLLTPEARKKLEQ 523
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
423-454 |
5.07e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 39.07 E-value: 5.07e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 423 EYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQ 454
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
822-853 |
7.30e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.68 E-value: 7.30e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 822 AYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQ 853
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
561-592 |
8.29e-04 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 38.30 E-value: 8.29e-04
10 20 30
....*....|....*....|....*....|..
gi 1039411581 561 AYKDCVSQAKTEAEKKECEKLLTPEAKKLLEE 592
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
3-812 |
9.19e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.19 E-value: 9.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 3 EENDKLETSKKAQQDSPQDLSNEEATEANHFENLLKESKESSDhhldnpTETQTHFDGDKSEETQTQMDSEGNETSessn 82
Cdd:pfam02463 223 EEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE------KLAQVLKENKEEEKEKKLQEEELKLLA---- 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 83 gSLADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSNEEATEANH 162
Cdd:pfam02463 293 -KEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 163 FENLLKESKESSDH-----HLDNPTETQTNFDGDKSEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRsifhyf 237
Cdd:pfam02463 372 EEELLAKKKLESERlssaaKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGK------ 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 238 mpLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISN 317
Cdd:pfam02463 446 --LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGR 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 318 GGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKtdEERNE 397
Cdd:pfam02463 524 IISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAV--LEIDP 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 398 CLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEaEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIP 477
Cdd:pfam02463 602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK-ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQE 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 478 QDLQKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEARKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKE 557
Cdd:pfam02463 681 LQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKE 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 558 SLKAYKDCVSQAKTEAEKKEcekllTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVK 637
Cdd:pfam02463 761 EKEEEKSELSLKEKELAEER-----EKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEEL 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 638 AYLdcvsrARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTDKERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKT 717
Cdd:pfam02463 836 EEL-----ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 718 EAEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEEEAKESVKAYLDCVSQAKNEAE 797
Cdd:pfam02463 911 LLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERY 990
|
810
....*....|....*
gi 1039411581 798 KKECEKLLTLESKKK 812
Cdd:pfam02463 991 NKDELEKERLEEEKK 1005
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
707-738 |
1.15e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.15e-03
10 20 30
....*....|....*....|....*....|..
gi 1039411581 707 AYLDCVSQAKTEAEKKECEKLLTPEARKLLEE 738
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
745-776 |
1.15e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.15e-03
10 20 30
....*....|....*....|....*....|..
gi 1039411581 745 AYLDCVSQAKTEAEKKECEKLLTPEARKLLEE 776
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
929-960 |
1.15e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.15e-03
10 20 30
....*....|....*....|....*....|..
gi 1039411581 929 AYLDCVSQAKTEAEKKECEKLLTPEARKLLEE 960
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLLQ 32
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
455-485 |
1.22e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 37.91 E-value: 1.22e-03
10 20 30
....*....|....*....|....*....|.
gi 1039411581 455 QALDCLKNAKTDEERNECLKNIPQDLQKELL 485
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLL 31
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
3-598 |
1.38e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 3 EENDKLETSKKAQQDSPQDLSNEEATEANHFENLLK---ESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNETSE 79
Cdd:PTZ00121 1287 EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKkaeEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA 1366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 80 SSngslADKLFKKARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSNEEATE 159
Cdd:PTZ00121 1367 EA----AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 160 ANHFENLLKESKESSD-HHLDNPTEtqtnfDGDKSEEITDDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRsifhyfm 238
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKaEEAKKKAE-----EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK------- 1510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 239 pledKSSRFSKDRNLYVNDEIQIRQEYNRllKERNEKGNMIDKNlffndDPNRTLYNYLNIAEIEDKNPLRAFYECISNG 318
Cdd:PTZ00121 1511 ----KADEAKKAEEAKKADEAKKAEEAKK--ADEAKKAEEKKKA-----DELKKAEELKKAEEKKKAEEAKKAEEDKNMA 1579
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 319 GNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNA-KTEEERIKCLDLIKDENLKKSLLNQQKvqvaldclknaKTDEERNE 397
Cdd:PTZ00121 1580 LRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAkKAEEAKIKAEELKKAEEEKKKVEQLKK-----------KEAEEKKK 1648
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 398 CLKLINDPEiREKFRKELELQKELQEYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQQALdclkNAKTDEERNEClknip 477
Cdd:PTZ00121 1649 AEELKKAEE-ENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL----KKKEAEEKKKA----- 1718
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 478 qdlqKELLADMSVKAYKDCVSKARNEKEKQECEKLLTPEA-RKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAK 556
Cdd:PTZ00121 1719 ----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEeKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1039411581 557 ESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESV 598
Cdd:PTZ00121 1795 EVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVA 1836
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
12-204 |
5.70e-03 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 41.70 E-value: 5.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 12 KKAQQDSPQDLSNEEATEANHFENLLKESKESSDHHLDNPTETQTHFDGDKSEETQTQMDSEGNeTSESSNGSLADKLFK 91
Cdd:PTZ00341 903 KKAKKKDAKDLSGNIAHEINLINKELKNQNENVPEHLKEHAEANIEEDAEENVEEDAEENVEEN-VEENVEENVEENVEE 981
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039411581 92 KARKLVDNKKPFTQQKNLDEETQELNEEDDQENNEYQEETQTDLIDDETSKKTQQHSPQDLSN-EEATEANHFENLLKES 170
Cdd:PTZ00341 982 NVEENVEENVEENVEENVEENIEENVEENVEENIEENVEEYDEENVEEVEENVEEYDEENVEEiEENAEENVEENIEENI 1061
|
170 180 190
....*....|....*....|....*....|....*
gi 1039411581 171 KESSDHHLDNPTET-QTNFDGDKSEEITDDSNDQE 204
Cdd:PTZ00341 1062 EEYDEENVEEIEENiEENIEENVEENVEENVEEIE 1096
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
670-700 |
6.35e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 35.98 E-value: 6.35e-03
10 20 30
....*....|....*....|....*....|.
gi 1039411581 670 QALDCLKNAKTDKERKKCLKDLPKDLQKKVL 700
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLL 31
|
|
| CagY_M |
pfam07337 |
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island ... |
1145-1175 |
6.74e-03 |
|
DC-EC Repeat; This repeat is found in the CagY proteins - part of the CAG pathogenicity island - and involved in delivery of the protein CagA into host cells. It forms part of a surface needle structure, and this repeat may form an alpha-helical rod structure. A conserved -DC- and -EC- can be seen in regularly spaced in the alignment.
Pssm-ID: 284699 [Multi-domain] Cd Length: 32 Bit Score: 35.98 E-value: 6.74e-03
10 20 30
....*....|....*....|....*....|.
gi 1039411581 1145 QVLNCLEKAGNEEERKACLKNLPKDLQENIL 1175
Cdd:pfam07337 1 QYKDCLKNAKTEEERNECLKGLSDEARKLLL 31
|
|
| |
