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Conserved domains on  [gi|1037261086|gb|ANL01178|]
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sugar ABC transporter permease protein (plasmid) [Rhizobium sp. N621]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 28-278 1.22e-77

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 236.92  E-value: 1.22e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEIVLWPSTNFVENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGR 107
Cdd:COG0395    30 FPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYALARFRFRGR 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 108 SVVIAIILGTITLPFSVVVIPQFIMVaREFKLANTWVALIVPPLF--NSLGVLFMRQSFSMMPGELFDAARVEGVKEWQI 185
Cdd:COG0395   110 KLLFLLILATLMIPGQVLLIPLYLLF-RQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEAARIDGASEFRI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 186 FLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLIGLTKVSWGGIMAGAVLLTAPILVVFVALQ 265
Cdd:COG0395   189 FWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATLPVLILFLFLQ 268

                         250
                  ....*....|...
gi 1037261086 266 RHFIAGIAAGAIK 278
Cdd:COG0395   269 RYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 28-278 1.22e-77

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 236.92  E-value: 1.22e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEIVLWPSTNFVENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGR 107
Cdd:COG0395    30 FPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYALARFRFRGR 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 108 SVVIAIILGTITLPFSVVVIPQFIMVaREFKLANTWVALIVPPLF--NSLGVLFMRQSFSMMPGELFDAARVEGVKEWQI 185
Cdd:COG0395   110 KLLFLLILATLMIPGQVLLIPLYLLF-RQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEAARIDGASEFRI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 186 FLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLIGLTKVSWGGIMAGAVLLTAPILVVFVALQ 265
Cdd:COG0395   189 FWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATLPVLILFLFLQ 268

                         250
                  ....*....|...
gi 1037261086 266 RHFIAGIAAGAIK 278
Cdd:COG0395   269 RYFVRGLTAGAVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
28-272 6.33e-33

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 121.77  E-value: 6.33e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEIVLWPSTNFVENFKNL------QADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALAR 101
Cdd:PRK10973   25 FPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIwvngvgNNSAPFGRMLLNSFVMAFSITVGKITVSMLSAFAIVW 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 102 YRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAReFKLANTWVALIVPPLFNSLGVLFMRQSFSMMPGELFDAARVEGVK 181
Cdd:PRK10973  105 FRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIAN-LKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGAS 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 182 EWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLI--GLTKVSWGGIMAGAVLLTAPILV 259
Cdd:PRK10973  184 PMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIatGEGTTEWNQVMAAMLLTLIPPVV 263

                         250
                  ....*....|...
gi 1037261086 260 VFVALQRHFIAGI 272
Cdd:PRK10973  264 IVLAMQRAFVRGL 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-258 1.80e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  74 MVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAREFKLAN-----TWVALIV 148
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGIlpglgLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 149 PPLFNSLGVLFMRQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTA 228
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1037261086 229 PVALGTLIGLTKVSWGGIMAGAVLLTAPIL 258
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 98-272 2.18e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 49.99  E-value: 2.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  98 ALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAREFKLANTWVALIVPPLFNSLGVLFMRQSFSMMPGELFDAARV 177
Cdd:pfam00528   9 ALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 178 EGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLIGLTkvSWGGIMAGAVLLTAPI 257
Cdd:pfam00528  89 LGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP--EIQGPVLAAALILLLL 166

                         170
                  ....*....|....*
gi 1037261086 258 LVVFVALQRHFIAGI 272
Cdd:pfam00528 167 NLLVDILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 9-263 1.86e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.28  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086   9 LIRQIALHAALAPLALIWLFPLWMMFVFSTMPDNGIFNPeivlwpstnfVENFKNLQADTDFVGAMVISIGVALIYTVLS 88
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSDGDFIG----------LANFAEYFATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  89 VMLTSMAGWALARYRFVG----RSVVIAIILGTITLP-FSVVVIPQFIMVAREFKLANT---WVALIVPPLFNSLGVLFM 160
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGkgafRLVALLPLLAPSLLPaISLIYLFGNQGLLKGLLGGFSiygFWGIVIGEVFYTFPHALM 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 161 --RQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMtAPVALGTLIGL 238
Cdd:TIGR03262 151 ilVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNVL-ATDIYKQVIGQ 229

                         250       260
                  ....*....|....*....|....*
gi 1037261086 239 TKVSWGGIMagAVLLTAPILVVFVA 263
Cdd:TIGR03262 230 QNFPMGAVV--GVLLLLPALLAFGI 252
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 28-278 1.22e-77

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 236.92  E-value: 1.22e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEIVLWPSTNFVENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGR 107
Cdd:COG0395    30 FPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYALARFRFRGR 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 108 SVVIAIILGTITLPFSVVVIPQFIMVaREFKLANTWVALIVPPLF--NSLGVLFMRQSFSMMPGELFDAARVEGVKEWQI 185
Cdd:COG0395   110 KLLFLLILATLMIPGQVLLIPLYLLF-RQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEAARIDGASEFRI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 186 FLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLIGLTKVSWGGIMAGAVLLTAPILVVFVALQ 265
Cdd:COG0395   189 FWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATLPVLILFLFLQ 268

                         250
                  ....*....|...
gi 1037261086 266 RHFIAGIAAGAIK 278
Cdd:COG0395   269 RYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 28-278 2.48e-35

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 127.96  E-value: 2.48e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEivLWPSTNFVENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGR 107
Cdd:COG3833    31 FPILWVVSASFNPGGSLYSSS--LIPENFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAALAAYAFSRFRFKGR 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 108 SVVIAIILGTITLPFSVVVIPQFIMVAReFKLANTWVALIVPPLFNSLGVLF--MRQSFSMMPGELFDAARVEGVKEWQI 185
Cdd:COG3833   109 KAGLLALLLLQMFPAFLALVALYLLLSA-LGLLNTLLGLILVYLGGAIPFNTwlMKGYFDTIPKELDEAAKIDGASHFQI 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 186 FLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLI-GLTKVSWGGIMAGAVLLTAPILVVFVAL 264
Cdd:COG3833   188 FFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVsDQRNTNWGVFAAGAVLVAIPIVILFLFL 267

                         250
                  ....*....|....
gi 1037261086 265 QRHFIAGIAAGAIK 278
Cdd:COG3833   268 QRYLVSGLTAGGVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
28-272 6.33e-33

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 121.77  E-value: 6.33e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEIVLWPSTNFVENFKNL------QADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALAR 101
Cdd:PRK10973   25 FPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIwvngvgNNSAPFGRMLLNSFVMAFSITVGKITVSMLSAFAIVW 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 102 YRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAReFKLANTWVALIVPPLFNSLGVLFMRQSFSMMPGELFDAARVEGVK 181
Cdd:PRK10973  105 FRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIAN-LKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGAS 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 182 EWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLI--GLTKVSWGGIMAGAVLLTAPILV 259
Cdd:PRK10973  184 PMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIatGEGTTEWNQVMAAMLLTLIPPVV 263

                         250
                  ....*....|...
gi 1037261086 260 VFVALQRHFIAGI 272
Cdd:PRK10973  264 IVLAMQRAFVRGL 276
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 59-266 4.35e-16

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 75.92  E-value: 4.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  59 ENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAReFK 138
Cdd:COG1177    48 RWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSA-LG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 139 LANTWVALIVPPLFNSL--GVLFMRQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWP 216
Cdd:COG1177   127 LSGGLWGLILAHVVFTLpfVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVIT 206

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1037261086 217 LLInSRPGMMTAPVALGTLI--GLTKVswggIMAGAVLLTAPILVVFVALQR 266
Cdd:COG1177   207 LFL-AGPGVTTLPVYIYSMIrrGISPE----INALSTLLILLSLLLLLLAER 253
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 66-206 7.33e-12

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 64.00  E-value: 7.33e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  66 ADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVV------------VIPQFIMV 133
Cdd:COG0555    48 TSPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAgiallllfgpngWLGQLLAP 127

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1037261086 134 ArEFKLANTWVALIVPPLFNSLG--VLFMRQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILF 206
Cdd:COG0555   128 L-GIKVAFTPLGIVLAQTFVSLPfvVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAF 201
malG PRK10998
maltose ABC transporter permease MalG;
28-278 1.61e-11

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 63.19  E-value: 1.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDN---GIFNPEIVLWPSTNFVENFKNLQADTDFVGA-------MVISIGVALIYTVLSVMLTSMAGW 97
Cdd:PRK10998   29 FPLLMVIAISLREGNfatGSLIPEQISWEHWKLALGFSVEHADGRVTPPpfpvllwLWNSVKVAGITAIGIVALSTTCAY 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  98 ALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAR-----EFKLANTWVALIVPPLFN-SLGVLFMRQSFSMMPGEL 171
Cdd:PRK10998  109 AFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRlgqyiPFIGLNTHGGVIFAYLGGiALHVWTIKGYFETIDSSL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 172 FDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLIGLTKVSWGGIMAGAV 251
Cdd:PRK10998  189 EEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAV 268

                         250       260
                  ....*....|....*....|....*..
gi 1037261086 252 LLTAPILVVFVALQRHFIAGIAAGAIK 278
Cdd:PRK10998  269 LSAIPITVVFLLAQRWLVGGLTAGGVK 295
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
59-213 7.51e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 62.10  E-value: 7.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  59 ENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPfSVVVIPQFIMVAREFK 138
Cdd:COG1178    41 ANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALP-PYVVALAWIALFGPNG 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 139 LANTWVA----LIVPPLFNSLGVLFM-------------RQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAAL 201
Cdd:COG1178   120 LLNTLLRalfgLEPPDIYGLGGIILVlvlfnypyvylllRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAG 199

                         170
                  ....*....|..
gi 1037261086 202 AIILFLHSWNNY 213
Cdd:COG1178   200 ALLVFLLCLADF 211
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 74-258 1.80e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.80e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  74 MVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAREFKLAN-----TWVALIV 148
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGIlpglgLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 149 PPLFNSLGVLFMRQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTA 228
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180       190
                  ....*....|....*....|....*....|
gi 1037261086 229 PVALGTLIGLTKVSWGGIMAGAVLLTAPIL 258
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
59-266 1.90e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 57.86  E-value: 1.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  59 ENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAR--E 136
Cdd:COG1178   325 DNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRplP 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 137 FKLANTWVALIVpplfnSLGVLFM-------RQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHS 209
Cdd:COG1178   405 LLLYGTLAILVL-----AYVVRFLpfalrslEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTS 479

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1037261086 210 WNNYLWPLLInSRPGMMTAPVALGTLIGltKVSWGGIMAGAVLLTAPILVVFVALQR 266
Cdd:COG1178   480 MKELSATLLL-RPPGFETLAVLIYQLAS--SGRYGEAAALALLLVLVSLLPVLLLER 533
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 28-268 1.55e-08

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 54.38  E-value: 1.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFNPEIVLWpstnfVENFKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGR 107
Cdd:COG1176    28 LPLLLLLVYSFTTRDPYGGVVPGFT-----LENYARLFTDPLYLKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPRWR 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 108 SVVIAIILGTITLPFSVVVIPQFIMVAREFKLANT--WVALIVPP---LFNSLGVL---------FM----RQSFSMMPG 169
Cdd:COG1176   103 NLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLllALGLIDEPlrlLYTEFAVViglvyvylpFMvlplYAALEKIDP 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 170 ELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMtapvaLGTLI---GLTKVSWGGI 246
Cdd:COG1176   183 SLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLM-----IGNLIyqqFLSALNWPLA 257

                         250       260
                  ....*....|....*....|..
gi 1037261086 247 MAGAVLLTAPILVVFVALQRHF 268
Cdd:COG1176   258 AALAVVLLLIVLLVLLLYLRLL 279
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 98-272 2.18e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 49.99  E-value: 2.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  98 ALARYRFVGRSVVIAIILGTITLPFSVVVIPQFIMVAREFKLANTWVALIVPPLFNSLGVLFMRQSFSMMPGELFDAARV 177
Cdd:pfam00528   9 ALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 178 EGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMTAPVALGTLIGLTkvSWGGIMAGAVLLTAPI 257
Cdd:pfam00528  89 LGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP--EIQGPVLAAALILLLL 166

                         170
                  ....*....|....*
gi 1037261086 258 LVVFVALQRHFIAGI 272
Cdd:pfam00528 167 NLLVDILQRLLDPRV 181
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
28-213 2.72e-06

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 47.82  E-value: 2.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  28 FPLWMMFVFSTMPDNGIFnpeivlwPSTNFV--ENFKNLQADTDFVGAMVISigvaLIYTVLSVMLTSMAGWALA---RY 102
Cdd:COG1175    37 YPLLYTLYLSFTDWNLLG-------PPPEFVglDNYARLFTDPRFWNALGNT----LLFTVVSVPLQLVLGLLLAlllNR 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 103 RFVGRSVVIAIILGTITLPFSVVVIPQFIMVAREFKLANTWVALI----VPPLFNSLGVLFM-------RQS-FSMM--- 167
Cdd:COG1175   106 KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALglepINWLGDPSLALPAviivtvwKGTgFNMLifl 185

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1037261086 168 ------PGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNY 213
Cdd:COG1175   186 aglqsiPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVF 237
modB PRK09421
molybdate ABC transporter permease subunit;
73-206 5.41e-05

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 43.37  E-value: 5.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  73 AMVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVV------------VIPQFIMVAREFKLA 140
Cdd:PRK09421   10 AVLLSLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVTgylllismgrrgFIGQWLYEWFGISFA 89

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1037261086 141 NTW--VALIVPPLFNSLGVLFMRQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILF 206
Cdd:PRK09421   90 FSWrgAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 61-200 3.53e-04

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 41.12  E-value: 3.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  61 FKNLQADTDFVGAMVISIGVALIYTVLSVMLTSMAGWALARYRFVGRSVVIAIILGTITLPFSVVVIPQ---FIMVAREF 137
Cdd:PRK09500   46 YELLFNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLlvlFMLLGIQL 125

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1037261086 138 KLANTWVALIVPPL-FNSLGVLFMRQSFSmmpGELFDAARVEGVKEWQIFLRIALPLARPTMAA 200
Cdd:PRK09500  126 GFWSLLFAHITFCLpFVVVTVYSRLKGFD---VRMLEAAKDLGASEFTILRKIILPLALPAVAA 186
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 9-263 1.86e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.28  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086   9 LIRQIALHAALAPLALIWLFPLWMMFVFSTMPDNGIFNPeivlwpstnfVENFKNLQADTDFVGAMVISIGVALIYTVLS 88
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSDGDFIG----------LANFAEYFATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  89 VMLTSMAGWALARYRFVG----RSVVIAIILGTITLP-FSVVVIPQFIMVAREFKLANT---WVALIVPPLFNSLGVLFM 160
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGkgafRLVALLPLLAPSLLPaISLIYLFGNQGLLKGLLGGFSiygFWGIVIGEVFYTFPHALM 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086 161 --RQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHSWNNYLWPLLINSRPGMMtAPVALGTLIGL 238
Cdd:TIGR03262 151 ilVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNVL-ATDIYKQVIGQ 229

                         250       260
                  ....*....|....*....|....*
gi 1037261086 239 TKVSWGGIMagAVLLTAPILVVFVA 263
Cdd:TIGR03262 230 QNFPMGAVV--GVLLLLPALLAFGI 252
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
76-209 7.51e-03

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 37.04  E-value: 7.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1037261086  76 ISIGVALIYTVLSVMLTSmagWALARYRFVGRSVVIAIILGTITLP-----------FSVVVIPQFIMVAREFKLANTWV 144
Cdd:PRK10971   65 LSAFVASIFNAVFGLLMA---WILTRYRFPGRTLLDALMDLPFALPtavagltlaslFSVNGWYGEWLAKFDIKVTYTWL 141

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1037261086 145 ALIVPPLFNSLG--VLFMRQSFSMMPGELFDAARVEGVKEWQIFLRIALPLARPTMAALAIILFLHS 209
Cdd:PRK10971  142 GIAVAMAFTSIPfvVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRS 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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