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Conserved domains on  [gi|1034663473|ref|XP_016869668|]
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rab9 effector protein with kelch motifs isoform X5 [Homo sapiens]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 11459646)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-202 1.64e-26

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 105.24  E-value: 1.64e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  18 PRYEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGG-GERGAQ 96
Cdd:COG3055    12 PRSEAAAALLD---GKVYVAGGLSGGSASNSFEVYDPATNTWSE---LAPLPGPPRHHAAAVAQDGKLYVFGGfTGANPS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  97 PVQDTKLHVFDANTLTWSQpetLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGC 176
Cdd:COG3055    86 STPLNDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRDHL 162

                         170       180
                  ....*....|....*....|....*.
gi 1034663473 177 AAhsAVAMGKHVYIFGGMTPAGALDT 202
Cdd:COG3055   163 AA--AVLPDGKILVIGGRNGSGFSNT 186
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-202 1.64e-26

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 105.24  E-value: 1.64e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  18 PRYEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGG-GERGAQ 96
Cdd:COG3055    12 PRSEAAAALLD---GKVYVAGGLSGGSASNSFEVYDPATNTWSE---LAPLPGPPRHHAAAVAQDGKLYVFGGfTGANPS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  97 PVQDTKLHVFDANTLTWSQpetLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGC 176
Cdd:COG3055    86 STPLNDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRDHL 162

                         170       180
                  ....*....|....*....|....*.
gi 1034663473 177 AAhsAVAMGKHVYIFGGMTPAGALDT 202
Cdd:COG3055   163 AA--AVLPDGKILVIGGRNGSGFSNT 186
PLN02193 PLN02193
nitrile-specifier protein
 59-213 8.14e-21

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 91.94  E-value: 8.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  59 WTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGGGERGAQPVqDTKLHVFDANTLTWS-QPETLGNPPSPRHGHVMVAAGTK 137
Cdd:PLN02193  153 WIKVEQKGEGPGLRCSH-GIAQVGNKIYSFGGEFTPNQPI-DKHLYVFDLETRTWSiSPATGDVPHLSCLGVRMVSIGST 230

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034663473 138 LFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHW 213
Cdd:PLN02193  231 LYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKW 306
Kelch_3 pfam13415
Galactose oxidase, central domain;
82-134 1.04e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 44.97  E-value: 1.04e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034663473  82 GNQLYVFGGGERGAQPVqDTKLHVFDANTLTWsqpETLGNPPSPRHGHVMVAA 134
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTR-LNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-202 1.64e-26

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 105.24  E-value: 1.64e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  18 PRYEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGG-GERGAQ 96
Cdd:COG3055    12 PRSEAAAALLD---GKVYVAGGLSGGSASNSFEVYDPATNTWSE---LAPLPGPPRHHAAAVAQDGKLYVFGGfTGANPS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  97 PVQDTKLHVFDANTLTWSQpetLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGC 176
Cdd:COG3055    86 STPLNDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRDHL 162

                         170       180
                  ....*....|....*....|....*.
gi 1034663473 177 AAhsAVAMGKHVYIFGGMTPAGALDT 202
Cdd:COG3055   163 AA--AVLPDGKILVIGGRNGSGFSNT 186
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-203 5.93e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 98.30  E-value: 5.93e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  18 PRYEHASFIPSctpDRIWVFGGANQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAAIGNQLYVFGGGErgaqp 97
Cdd:COG3055   111 PRGGATALLLD---GKIYVVGGWDDGGNVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAAVLPDGKILVIGGRN----- 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  98 vqdtklhvFDANTLTWSqpeTLGNPPSPRHGHVMVAAGTKLFIHGGLAGdrFYDDLHCIDISDMKWQKLNPTgaaPAGCA 177
Cdd:COG3055   180 --------GSGFSNTWT---TLAPLPTARAGHAAAVLGGKILVFGGESG--FSDEVEAYDPATNTWTALGEL---PTPRH 243

                         170       180
                  ....*....|....*....|....*.
gi 1034663473 178 AHSAVAMGKHVYIFGGMTPAGALDTM 203
Cdd:COG3055   244 GHAAVLTDGKVYVIGGETKPGVRTPL 269
PLN02193 PLN02193
nitrile-specifier protein
 59-213 8.14e-21

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 91.94  E-value: 8.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  59 WTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGGGERGAQPVqDTKLHVFDANTLTWS-QPETLGNPPSPRHGHVMVAAGTK 137
Cdd:PLN02193  153 WIKVEQKGEGPGLRCSH-GIAQVGNKIYSFGGEFTPNQPI-DKHLYVFDLETRTWSiSPATGDVPHLSCLGVRMVSIGST 230

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034663473 138 LFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHW 213
Cdd:PLN02193  231 LYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKW 306
PLN02153 PLN02153
epithiospecifier protein
 69-212 3.64e-20

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 88.89  E-value: 3.64e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  69 PSPRTFHtSSAAIGNQLYVFGGgERGAQPVQDTKLHVFDANTLTWSQPETLGNPPS-PRHGHVMVAAGTKLFIHGGLAGD 147
Cdd:PLN02153   20 PGPRCSH-GIAVVGDKLYSFGG-ELKPNEHIDKDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAVGTKLYIFGGRDEK 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034663473 148 RFYDDLHCIDISDMKWQ---KLNPTGAaPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQH 212
Cdd:PLN02153   98 REFSDFYSYDTVKNEWTfltKLDEEGG-PEARTFHSMASDENHVYVFGGVSKGGLMKTPERFRTIEAY 164
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-216 7.75e-20

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 7.75e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  58 TWTTpevTSPPPSPRTfHTSSAAIGNQLYVFGGGERGAQPvqdTKLHVFDANTLTWSQpetLGNPP-SPRHGHVMVAAGT 136
Cdd:COG3055     2 TWSS---LPDLPTPRS-EAAAALLDGKVYVAGGLSGGSAS---NSFEVYDPATNTWSE---LAPLPgPPRHHAAAVAQDG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473 137 KLFIHGGLAGD----RFYDDLHCIDISDMKWQKLNPtgaAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQH 212
Cdd:COG3055    72 KLYVFGGFTGAnpssTPLNDVYVYDPATNTWTKLAP---MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGT 148


                  ....
gi 1034663473 213 WTLL 216
Cdd:COG3055   149 WTQL 152
PLN02193 PLN02193
nitrile-specifier protein
 2-216 3.05e-15

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 75.76  E-value: 3.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473   2 DLGKHQWDLDTCKGLLPryeHASFIPSC---TPDRIWVFGGANQSGNRNCLQVLNPETRTWTTPEVTSPPPSPRTFHtSS 78
Cdd:PLN02193  199 DLETRTWSISPATGDVP---HLSCLGVRmvsIGSTLYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFH-SM 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  79 AAIGNQLYVFGGGERGAqpvqdtKLHVFDANTL---TWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFyDDLHC 155
Cdd:PLN02193  275 AADEENVYVFGGVSATA------RLKTLDSYNIvdkKWFHCSTPGDSFSIRGGAGLEVVQGKVWVVYGFNGCEV-DDVHY 347

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473 156 IDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGG---------MTPAGALDTMYQYHTEEQHWTLL 216
Cdd:PLN02193  348 YDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGGeiamdplahVGPGQLTDGTFALDTETLQWERL 417
PLN02153 PLN02153
epithiospecifier protein
 2-193 1.36e-12

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 67.32  E-value: 1.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473   2 DLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLNPETRTWT--TPEVTSPPPSPRTFHtSSA 79
Cdd:PLN02153   56 DFNTHTWSIAPANGDVPRISCLGVRMVAVGTKLYIFGGRDEKREFSDFYSYDTVKNEWTflTKLDEEGGPEARTFH-SMA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  80 AIGNQLYVFGGGERGAQPVQDTKLHVFDANTLT---WSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLA------GDRFY 150
Cdd:PLN02153  135 SDENHVYVFGGVSKGGLMKTPERFRTIEAYNIAdgkWVQLPDPGENFEKRGGAGFAVVQGKIWVVYGFAtsilpgGKSDY 214

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1034663473 151 DD--LHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGG 193
Cdd:PLN02153  215 ESnaVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGG 259
PLN02153 PLN02153
epithiospecifier protein
 120-231 2.86e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 63.47  E-value: 2.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473 120 GNPPSPRHGHVMVAAGTKLFIHGG-LAGDRFYD-DLHCIDISDMKWQKLNPTGAAPA-GCAAHSAVAMGKHVYIFGGMTP 196
Cdd:PLN02153   17 GKGPGPRCSHGIAVVGDKLYSFGGeLKPNEHIDkDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAVGTKLYIFGGRDE 96

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1034663473 197 AGALDTMYQYHTEEQHWTLL-KFDTL-LPPGRLDHSM 231
Cdd:PLN02153   97 KREFSDFYSYDTVKNEWTFLtKLDEEgGPEARTFHSM 133
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
112-231 5.42e-11

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 62.10  E-value: 5.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473 112 TWSqpeTLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAhsAVAMGKHVYIF 191
Cdd:COG3055     2 TWS---SLPDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAPLPGPPRHHAA--AVAQDGKLYVF 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1034663473 192 GGMTPA----GALDTMYQYHTEEQHWTLLkfdTLLPPGRLDHSM 231
Cdd:COG3055    77 GGFTGAnpssTPLNDVYVYDPATNTWTKL---APMPTPRGGATA 117
PRK14131 PRK14131
N-acetylneuraminate epimerase;
78-193 3.18e-09

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 57.33  E-value: 3.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  78 SAAIGNQLYVfGGGERGaqpvqdTKLHVFDANTLT--WSQPETLgnPPSPRHGHVMVAAGTKLFIHGGL------AGDRF 149
Cdd:PRK14131   34 GAIDNNTVYV-GLGSAG------TSWYKLDLNAPSkgWTKIAAF--PGGPREQAVAAFIDGKLYVFGGIgktnseGSPQV 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1034663473 150 YDDLHCIDISDMKWQKLNPTgaAPAGCAAHSAVAM-GKHVYIFGG 193
Cdd:PRK14131  105 FDDVYKYDPKTNSWQKLDTR--SPVGLAGHVAVSLhNGKAYITGG 147
PLN02153 PLN02153
epithiospecifier protein
 14-226 5.37e-07

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 50.37  E-value: 5.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  14 KGLLPRYEHASfipSCTPDRIWVFGG---ANQSGNRNcLQVLNPETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGG 90
Cdd:PLN02153   18 KGPGPRCSHGI---AVVGDKLYSFGGelkPNEHIDKD-LYVFDFNTHTWSIAPANGDVPRISCLGVRMVAVGTKLYIFGG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  91 GErgaQPVQDTKLHVFDANTLTW---SQPETLGNPPSpRHGHVMVAAGTKLFIHGGLAG-------DRFyDDLHCIDISD 160
Cdd:PLN02153   94 RD---EKREFSDFYSYDTVKNEWtflTKLDEEGGPEA-RTFHSMASDENHVYVFGGVSKgglmktpERF-RTIEAYNIAD 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034663473 161 MKWQKL-NPTGAAPAGCAAHSAVAMGKHVYIFGGMT---PAGALD----TMYQYHTEEQHWTLLKFDTLLPPGR 226
Cdd:PLN02153  169 GKWVQLpDPGENFEKRGGAGFAVVQGKIWVVYGFATsilPGGKSDyesnAVQFFDPASGKWTEVETTGAKPSAR 242
Kelch_3 pfam13415
Galactose oxidase, central domain;
82-134 1.04e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 44.97  E-value: 1.04e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034663473  82 GNQLYVFGGGERGAQPVqDTKLHVFDANTLTWsqpETLGNPPSPRHGHVMVAA 134
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTR-LNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
32-80 2.76e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 43.82  E-value: 2.76e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1034663473  32 DRIWVFGGANQSGNR--NCLQVLNPETRTWTTpevTSPPPSPRTFHTSSAA 80
Cdd:pfam13415   2 DKLYIFGGLGFDGQTrlNDLYVYDLDTNTWTQ---IGDLPPPRSGHSATYI 49
Kelch_6 pfam13964
Kelch motif;
71-126 4.85e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 43.09  E-value: 4.85e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034663473  71 PRTFHtSSAAIGNQLYVFGGGERGAQPVQdtKLHVFDANTLTWsqpETLGNPPSPR 126
Cdd:pfam13964   1 PRTFH-SVVSVGGYIYVFGGYTNASPALN--KLEVYNPLTKSW---EELPPLPTPR 50
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
18-107 8.17e-06

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 46.30  E-value: 8.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  18 PRYEHASFIPSctpDRIWVFGGanQSGNRNCLQVLNPETRTWTTpevTSPPPSPRTFHTSsAAIGNQLYVFGGG-ERGAQ 96
Cdd:COG3055   196 ARAGHAAAVLG---GKILVFGG--ESGFSDEVEAYDPATNTWTA---LGELPTPRHGHAA-VLTDGKVYVIGGEtKPGVR 266

                          90
                  ....*....|.
gi 1034663473  97 PVQDTKLHVFD 107
Cdd:COG3055   267 TPLVTSAEVYD 277
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 176-216 1.68e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 41.44  E-value: 1.68e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1034663473 176 CAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLL 216
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKL 42
PLN02153 PLN02153
epithiospecifier protein
 33-154 2.60e-05

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 45.36  E-value: 2.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  33 RIWV-FG-------GANQSGNRNCLQVLNPETRTWTTPEVTSPPPSPRTFHtSSAAIGNQLYVFGG-------GERGAQP 97
Cdd:PLN02153  195 KIWVvYGfatsilpGGKSDYESNAVQFFDPASGKWTEVETTGAKPSARSVF-AHAVVGKYIIIFGGevwpdlkGHLGPGT 273

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034663473  98 VQDTKlHVFDANTLTWSQPETLGNPPSPRHGHVMVAA---GTK-LFIHGG-LAGDRFYDDLH 154
Cdd:PLN02153  274 LSNEG-YALDTETLVWEKLGECGEPAMPRGWTAYTTAtvyGKNgLLMHGGkLPTNERTDDLY 334
PRK14131 PRK14131
N-acetylneuraminate epimerase;
45-205 5.98e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 44.24  E-value: 5.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  45 NRNCLqVLNPETRTWTTPEVTsppPSPRTFHTSSAAIGNQLYVFGG----GERGAQpvqdTKLHVFDANTLTWSQPETLg 120
Cdd:PRK14131  188 NKEVL-SYDPSTNQWKNAGES---PFLGTAGSAVVIKGNKLWLINGeikpGLRTDA----VKQGKFTGNNLKWQKLPDL- 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473 121 nPPSPR---------------HGHVMVAAGT------------KLFIHGGLAgDRFYDDLHCIDisDMKWQKLnptGAAP 173
Cdd:PRK14131  259 -PPAPGgssqegvagafagysNGVLLVAGGAnfpgarenyqngKLYAHEGLK-KSWSDEIYALV--NGKWQKV---GELP 331

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1034663473 174 AGCAAHSAVAMGKHVYIFGGMTPAG-ALDTMYQ 205
Cdd:PRK14131  332 QGLAYGVSVSWNNGVLLIGGETAGGkAVSDVTL 364
PHA03098 PHA03098
kelch-like protein; Provisional
 32-234 9.29e-05

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 43.60  E-value: 9.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473  32 DRIWVFGGANQSGNR-NCLQVLNPETRTWTT-PEVTSPPPSPrtfhtSSAAIGNQLYVFGGgERGAQPVQDTKLHVFDAN 109
Cdd:PHA03098  295 NVIYFIGGMNKNNLSvNSVVSYDTKTKSWNKvPELIYPRKNP-----GVTVFNNRIYVIGG-IYNSISLNTVESWKPGES 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663473 110 TltWSQPETLgnpPSPRHGHVMVAAGTKLFIHGGLA-GDRFYDDLHCIDISDMKWQKLNPTgaaPAGCAAHSAVAMGKHV 188
Cdd:PHA03098  369 K--WREEPPL---IFPRYNPCVVNVNNLIYVIGGISkNDELLKTVECFSLNTNKWSKGSPL---PISHYGGCAIYHDGKI 440

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1034663473 189 YIFGGMTPA---GALDTMYQYHTEEQHWTLLKfdTLLPPgRLDHSMCII 234
Cdd:PHA03098  441 YVIGGISYIdniKVYNIVESYNPVTNKWTELS--SLNFP-RINASLCIF 486
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 125-168 1.02e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 39.13  E-value: 1.02e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1034663473 125 PRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNP 168
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPS 44
Kelch_4 pfam13418
Galactose oxidase, central domain;
71-124 1.35e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 38.75  E-value: 1.35e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034663473  71 PRTFHTSSAAIGNQLYVFGGgeRGAQPVQDTKLHVFDANTLTWSQpetLGNPPS 124
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGG--EGEDGTLLSDLWVFDLSTNEWTR---LGSLPS 49
Kelch_6 pfam13964
Kelch motif;
18-72 2.66e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.09  E-value: 2.66e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034663473  18 PRYEHASFIPSctpDRIWVFGGANQSGNR-NCLQVLNPETRTWttpEVTSPPPSPR 72
Cdd:pfam13964   1 PRTFHSVVSVG---GYIYVFGGYTNASPAlNKLEVYNPLTKSW---EELPPLPTPR 50
Kelch_4 pfam13418
Galactose oxidase, central domain;
18-69 2.72e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.98  E-value: 2.72e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1034663473  18 PRYEHASFipSCTPDRIWVFGGANQSGNR-NCLQVLNPETRTWTTpeVTSPPP 69
Cdd:pfam13418   1 PRAYHTST--SIPDDTIYLFGGEGEDGTLlSDLWVFDLSTNEWTR--LGSLPS 49
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 123-154 3.93e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 37.54  E-value: 3.93e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1034663473 123 PSPRHGHVMVAAGTKLFIHGGLAGDR--FYDDLH 154
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEgqPSDDVY 34
Kelch_4 pfam13418
Galactose oxidase, central domain;
125-166 4.40e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.59  E-value: 4.40e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1034663473 125 PRHGHVMVA-AGTKLFIHGGLAGD-RFYDDLHCIDISDMKWQKL 166
Cdd:pfam13418   1 PRAYHTSTSiPDDTIYLFGGEGEDgTLLSDLWVFDLSTNEWTRL 44
PLN02772 PLN02772
guanylate kinase
 77-147 6.23e-04

guanylate kinase


Pssm-ID: 215414 [Multi-domain]  Cd Length: 398  Bit Score: 40.98  E-value: 6.23e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034663473  77 SSAAIGNQLYVFGGGERGAQPVQDTKLhvFDANTLTWSQPETLGNPPSPRHGH--VMVAAGTKLFIHGGLAGD 147
Cdd:PLN02772   29 TSVTIGDKTYVIGGNHEGNTLSIGVQI--LDKITNNWVSPIVLGTGPKPCKGYsaVVLNKDRILVIKKGSAPD 99
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 173-209 6.84e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 33.69  E-value: 6.84e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1034663473 173 PAGCAAHSAVAMGKHVYIFGGMTPAG--ALDTMYQYHTE 209
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEgqPSDDVYVLSLP 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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