|
Name |
Accession |
Description |
Interval |
E-value |
| BRCT_MDC1_rpt2 |
cd18441 |
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1751-1831 |
1.56e-43 |
|
second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the second BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349394 Cd Length: 81 Bit Score: 152.92 E-value: 1.56e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1751 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEA 1830
Cdd:cd18441 1 LLEGYEIHVTPGVKPEPPQMKDIITCAGGTFLPSMPKTYKPQTVVISCPEDFPHCSPALKAGLPVVSAEFLLTGILRQEA 80
|
.
gi 1034652375 1831 K 1831
Cdd:cd18441 81 D 81
|
|
| FHA_MDC1 |
cd22665 |
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) ... |
53-152 |
9.90e-38 |
|
forkhead associated (FHA) domain found in mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also called nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438717 [Multi-domain] Cd Length: 97 Bit Score: 136.98 E-value: 9.90e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 53 GRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlRPPKVLSPGV 132
Cdd:cd22665 1 GRLKVFSQAHGPEKDFPLYEGENVIGRDPSCSVVLPDKSVSKQHACIEVDG--GTHLIEDLGSTNGTRI-GNKVRLKPNV 77
|
90 100
....*....|....*....|
gi 1034652375 133 SHRLRDQELILFADLLCQYH 152
Cdd:cd22665 78 RYELIDGDLLLFGDVKCQYV 97
|
|
| BRCT_MDC1_rpt1 |
cd17744 |
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; ... |
1649-1719 |
1.85e-27 |
|
first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the first BRCT domain.
Pssm-ID: 349375 [Multi-domain] Cd Length: 72 Bit Score: 106.93 E-value: 1.85e-27
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034652375 1649 PKVLFTGVVD-ARGERAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1719
Cdd:cd17744 1 PRVLFTGVSDkEEGEKIIKKLGGSVVDSVEDCTHLVTDKVRRTVKFLCALARGIPIVSPDWLEASIKANKFL 72
|
|
| BRCT_PAXIP1_rpt6_like |
cd18432 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA ... |
1751-1829 |
1.34e-26 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1), second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. MDC1, also termed nuclear factor with BRCT domains 1 (NFBD1), is a nuclear chromatin-associated protein that is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. MDC1 contains a forkhead-associated (FHA) domain and two BRCT domains, as well as an internal 41-amino acid repeat sequence. The family corresponds to the sixth BRCT domain of PAXIP1 and the second BRCT domain of MDC1.
Pssm-ID: 349385 [Multi-domain] Cd Length: 85 Bit Score: 104.97 E-value: 1.34e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1751 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMP----RSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVL 1826
Cdd:cd18432 1 LFEGYTFYVTPNVKPPPEELKEIIEAAGGKVLKKLPtkriEDDDPDTIVISCEEDRKLWKPLKKKGIPIYSVEFILTGIL 80
|
...
gi 1034652375 1827 KQE 1829
Cdd:cd18432 81 RQK 83
|
|
| BRCT_PAXIP1_rpt5 |
cd17712 |
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1648-1719 |
1.92e-20 |
|
fifth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the fifth BRCT domain.
Pssm-ID: 349344 Cd Length: 75 Bit Score: 86.91 E-value: 1.92e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034652375 1648 APKVLFTGVVDARGER---AVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1719
Cdd:cd17712 1 TPRVLFTGFDPVQVRKltkKVTILGGEVVESPQECTHLVAPKVSRTVKFLTAISVCKHIVTPEWLEESFKQGKFL 75
|
|
| BRCT_PAXIP1_rpt6 |
cd18440 |
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also ... |
1751-1829 |
7.96e-20 |
|
sixth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins; PAXIP1, also termed PAX transactivation activation domain-interacting protein (PTIP), is involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. It also facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. PAXIP1 contains six BRCT repeats. This family corresponds to the sixth BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.
Pssm-ID: 349393 Cd Length: 90 Bit Score: 85.73 E-value: 7.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1751 LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSmPRSYKPQR----------VVITCPQDFPHCSIPLRVGLPLLSPEF 1820
Cdd:cd18440 1 LFKGKYFYITPGVKPSPSVLKEIIESAGGKVEKK-RPSLKKIMeknnqgppsyIIITCENDLHLCRDLFRKNIDVYNAEF 79
|
....*....
gi 1034652375 1821 LLTGVLKQE 1829
Cdd:cd18440 80 ILTGVLRQK 88
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
983-1513 |
1.56e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 90.00 E-value: 1.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 983 ATRGRKNRSSVKTPEPVVPTAP-ELQPSTSTDQPVtSEPTYQAT----RGRKNRSSVKTPEPVVPTAPELRPSTsTDRPV 1057
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPsRLAPAILPDEPV-GEPVHPRMltwiRGLEELASDDAGDPPPPLPPAAPPAA-PDRSV 2568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1058 -TPKPTSRttrsrtnmssvktpetvvPTAPELQiSTSTDQPVTPKPTsrttRSRTNMSSVKNPESTVPIAPeLPPSTSTE 1136
Cdd:PHA03247 2569 pPPRPAPR------------------PSEPAVT-SRARRPDAPPQSA----RPRAPVDDRGDPRGPAPPSP-LPPDTHAP 2624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1137 QPVTPEPTSRATRGRKNRSSGKTP---ETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSvktPETVVPTAPELQP 1213
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPperPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA---RPTVGSLTSLADP 2701
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1214 StstDQPVTPEPTSQATrgrtdrsSVKTPETVVPTAPELQASASTDQPVTSEP--TSRTTRGRKNRSSVKTPETVVPAAP 1291
Cdd:PHA03247 2702 P---PPPPTPEPAPHAL-------VSATPLPPGPAAARQASPALPAAPAPPAVpaGPATPGGPARPARPPTTAGPPAPAP 2771
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1292 ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESivPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPT 1371
Cdd:PHA03247 2772 PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPAD--PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPS 2849
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1372 AP-----EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVR 1446
Cdd:PHA03247 2850 LPlggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQP 2929
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1447 AMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQR 1513
Cdd:PHA03247 2930 QPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
776-1396 |
9.92e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 80.75 E-value: 9.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 776 IRAAEKVSRGDQESPDACLPPTVPeAPAPPQKPLNSQSQKHLAPPPLlspllpsikpTVRKTRqdgsqeaPEAPlsseLE 855
Cdd:PHA03247 2537 IRGLEELASDDAGDPPPPLPPAAP-PAAPDRSVPPPRPAPRPSEPAV----------TSRARR-------PDAP----PQ 2594
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 856 PFHPKPKIRTRKSSRMTPfPATSAAPEPHPststaqpvtPKPTSQATRSRTNRSSVKTPepvVPTAPELQPSTSTDQPVT 935
Cdd:PHA03247 2595 SARPRAPVDDRGDPRGPA-PPSPLPPDTHA---------PDPPPPSPSPAANEPDPHPP---PTVPPPERPRDDPAPGRV 2661
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 936 SEPTSQVTRGRKSRSSvKTPETVVPTALE--LQPSTSTDRPVTSEPTSQAtrgRKNRSSVKTPEPVVPTAPELQPSTSTD 1013
Cdd:PHA03247 2662 SRPRRARRLGRAAQAS-SPPQRPRRRAARptVGSLTSLADPPPPPPTPEP---APHALVSATPLPPGPAAARQASPALPA 2737
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1014 QPVT-SEPTYQATRGRKNRssvkTPEPVVPTAPElRPSTSTDRPVTPKPtsRTTRSRTNMSSVKTPETVVPTAPelqist 1092
Cdd:PHA03247 2738 APAPpAVPAGPATPGGPAR----PARPPTTAGPP-APAPPAAPAAGPPR--RLTRPAVASLSESRESLPSPWDP------ 2804
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1093 STDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSteQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEP 1172
Cdd:PHA03247 2805 ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP--PPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPP 2882
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1173 STSTDQPVTPEPTSqatrgrtnrssvktPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgrtdrSSVKTPETVVPTAPEL 1252
Cdd:PHA03247 2883 VRRLARPAVSRSTE--------------SFALPPDQPERPPQPQAPPPPQPQPQPPP-------PPQPQPPPPPPPRPQP 2941
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1253 QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSvktpESIVPIAP 1332
Cdd:PHA03247 2942 PLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWAS----SLALHEET 3017
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1333 ELQPSTSRNQLVTPEPT--SRATRCRTNRSSVKTPEPVVPTAPEPH-PTTSTDQPVTPKLTSRATRR 1396
Cdd:PHA03247 3018 DPPPVSLKQTLWPPDDTedSDADSLFDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARESPS 3084
|
|
| FHA |
cd00060 |
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small ... |
54-131 |
9.12e-14 |
|
forkhead associated (FHA) domain superfamily; Forkhead-associated (FHA) domains are small phosphopeptide recognition modules mostly found in eubacteria and eukaryotes. It is about 95-120 residues long that fold into an 11-stranded beta-sandwich. FHA domains can mediate the recognition of phosphorylated and non-phosphorylated substrates, as well as protein oligomerization. They specifically recognize threonine phosphorylation (pThr) accompanying activation of protein serine/threonine kinases. FHA domains show diverse ligand specificity. They may recognize the pTXXD motif, the pTXXI/L motif, and TQ clusters (singly and multiply phosphorylated). In eukaryotes, FHA superfamily members include forkhead-type transcription factors, as well as other signaling proteins, such as many regulatory proteins, kinases, phosphatases, motor proteins called kinesins, and metabolic enzymes. Many of them localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. FHA domains play important roles in human diseases, particularly in relation to DNA damage responses and cancers. In bacteria, FHA domain-containing proteins may participate in injection of viral proteins into host cells, transmembrane transporters, and cell division. FHA domain-containing proteins rarely include more than one copy of the domain. The only exception in eukaryotes is the checkpoint kinase Rad53 from Saccharomyces cerevisiae, which harbors two FHA domains (FHA1 and FHA2) flanking a central kinase domain. The two FHA domains recognize different phosphorylated targets and function independently from one another. In contrast, Mycobacterium tuberculosis ABC transporter Rv1747 contains two FHA domains but only one of them is essential for protein function.
Pssm-ID: 438714 [Multi-domain] Cd Length: 92 Bit Score: 68.46 E-value: 9.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 54 RLHIFSGAHGPEKdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI----LRPPKVLS 129
Cdd:cd00060 1 RLIVLDGDGGGRE-FPLTKGVVTIGRSPDCDIVLDDPSVSRRHARIEVD--GGGVYLEDLGSTNGTFVngkrITPPVPLQ 77
|
..
gi 1034652375 130 PG 131
Cdd:cd00060 78 DG 79
|
|
| FHA |
COG1716 |
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]; |
53-131 |
1.95e-13 |
|
Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms];
Pssm-ID: 441322 [Multi-domain] Cd Length: 96 Bit Score: 67.68 E-value: 1.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 53 GRLHIFSGAHGpEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEilAWDKAPILRDCGSLNGTQI----LRPPKVL 128
Cdd:COG1716 2 ARLVVLEGPLA-GRRFPLDGGPLTIGRAPDNDIVLDDPTVSRRHARIR--RDGGGWVLEDLGSTNGTFVngqrVTEPAPL 78
|
...
gi 1034652375 129 SPG 131
Cdd:COG1716 79 RDG 81
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1118-1586 |
3.53e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 75.36 E-value: 3.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1118 NPESTVPIAPELPPSTSTEQP--VTPEPTSRATRGR-----------KNRSSGKTPETLVPTAPKLEPSTSTDQP-VTPE 1183
Cdd:PHA03247 2497 DPGGGGPPDPDAPPAPSRLAPaiLPDEPVGEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPAAPDRSVPPPrPAPR 2576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1184 PTSQATRGRTNRSSVKtPETVVPTAPeLQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1263
Cdd:PHA03247 2577 PSEPAVTSRARRPDAP-PQSARPRAP-VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRD 2654
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1264 SEPTSRTTRGRKNRSSVKTPEtvvPAAPELQPSTSTDQPVTPEPTSRATrgrtnrssvktpesivPIAPELQPSTSRNQL 1343
Cdd:PHA03247 2655 DPAPGRVSRPRRARRLGRAAQ---ASSPPQRPRRRAARPTVGSLTSLAD----------------PPPPPPTPEPAPHAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1344 VTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPV-TPKLTSRATRRKTNRSSVKTPKP--VEPAASDLEPFT 1420
Cdd:PHA03247 2716 VSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPaRPPTTAGPPAPAPPAAPAAGPPRrlTRPAVASLSESR 2795
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1421 PTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSA 1500
Cdd:PHA03247 2796 ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKP 2875
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1501 PLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSrkrSLATMDSPPHQ 1580
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP---PLAPTTDPAGA 2952
|
....*.
gi 1034652375 1581 KQPQRG 1586
Cdd:PHA03247 2953 GEPSGA 2958
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
767-1312 |
9.20e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.20 E-value: 9.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 767 MPPAEKASRirAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAP 846
Cdd:PHA03247 2568 VPPPRPAPR--PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 847 EAPLSSELEPFHPkPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQP 926
Cdd:PHA03247 2646 VPPPERPRDDPAP-GRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 927 STSTDQPVTSEPTSQVtrgrksrssvkTPETVVPTALELQPSTSTDRPVTSEPtsqatrgrknrssvktPEPVVPTAPEL 1006
Cdd:PHA03247 2725 PAAARQASPALPAAPA-----------PPAVPAGPATPGGPARPARPPTTAGP----------------PAPAPPAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1007 QPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET----VV 1082
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlggsVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1083 PTAPELQISTStdQPVTPKPTSRTTRSRTNMSSVKNPESTVPIApeLPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1162
Cdd:PHA03247 2858 PGGDVRRRPPS--RSPAAKPAAPARPPVRRLARPAVSRSTESFA--LPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1163 LVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKT- 1241
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLAl 3013
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034652375 1242 -PETVVPTAPELQASASTDQPVTSEPTSRttrgRKNRSSVKTPETVVPAAPELQ-PSTSTDQPVTPEPTSRAT 1312
Cdd:PHA03247 3014 hEETDPPPVSLKQTLWPPDDTEDSDADSL----FDSDSERSDLEALDPLPPEPHdPFAHEPDPATPEAGARES 3082
|
|
| BRCT_BRC1_like_rpt5 |
cd17743 |
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar ... |
1650-1716 |
1.75e-12 |
|
fifth BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contain six BRCT domains. This family corresponds to the fifth one.
Pssm-ID: 349374 Cd Length: 70 Bit Score: 64.19 E-value: 1.75e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034652375 1650 KVLFTGVVDARGE--RAVLALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1716
Cdd:cd17743 2 RLLFTGYKLWTEKeiKKLKKLGISIVEDPDECTHLVAPKIVRTEKFLCALAYAPVIVTTDWLEACLKAG 70
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
876-1216 |
2.57e-12 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 72.26 E-value: 2.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 876 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTApelQPSTSTDQPVTSEPTSQVTR---GRKSRSSV 952
Cdd:pfam05109 471 ADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTP---TPNATSPTPAVTTPTPNATSptlGKTSPTSA 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 953 KTPETvvPTALELQPSTSTDRPVTSEPTSQATrgrKNRSSVKTPEP--VVPTAPELQPSTST---------DQPVTSEP- 1020
Cdd:pfam05109 548 VTTPT--PNATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTtnhtlggtsSTPVVTSPp 622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1021 ---TYQATRGRKNRSSVKTpepvvpTAPELRPStSTDRPVTPKPTSRTTRSRTNMSSVKTP--ETVVPTAPElqiSTSTD 1095
Cdd:pfam05109 623 knaTSAVTTGQHNITSSST------SSMSLRPS-SISETLSPSTSDNSTSHMPLLTSAHPTggENITQVTPA---STSTH 692
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1096 QPVT----PKPTSRTTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPV---TPEPTSRATRGRKNRSSGKTPETLVPT 1166
Cdd:pfam05109 693 HVSTsspaPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPknATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGA 772
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034652375 1167 APKLEPST----STDQPVT--------PEPTSQATRGRTNRSS--VKTPETVVPTAPELQPSTS 1216
Cdd:pfam05109 773 RTSTEPTTdyggDSTTPRTrynattylPPSTSSKLRPRWTFTSppVTTAQATVPVPPTSQPRFS 836
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1078-1439 |
2.35e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 69.17 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1078 PETVVPTAPELQISTSTDQPVTPK-PTSRTTRSRTNMSSVKNPESTVPiapeLPPSTSTEQPVTPEPtsratrgrknrSS 1156
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKaPESTTTSPTLNTTGFAAPNTTTG----LPSSTHVPTNLTAPA-----------ST 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1157 GKTPETLVPTAPKLEPSTSTDQPVTPEPTSqatrgRTNRSSVKTPETVVPTAPELQPSTSTDQP----VTPEPTSQA-TR 1231
Cdd:pfam05109 465 GPTVSTADVTSPTPAGTTSGASPVTPSPSP-----RDNGTESKAPDMTSPTSAVTTPTPNATSPtpavTTPTPNATSpTL 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1232 GRTDRSSVKTPETvvPTAPELQASASTDQPVTSEPTSRTTrGRKNRSSVKTPETVVPAAPELQPSTST---------DQP 1302
Cdd:pfam05109 540 GKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGKT-SPTSAVTTPTPNATSPTVGETSPQANTtnhtlggtsSTP 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1303 VTPEP----TSRATRGRTNRSSVKTPE-SIVP--IAPELQPSTSRNQ------LVTPEPTSRATRCRTNRSSVKTpEPVV 1369
Cdd:pfam05109 617 VVTSPpknaTSAVTTGQHNITSSSTSSmSLRPssISETLSPSTSDNStshmplLTSAHPTGGENITQVTPASTST-HHVS 695
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034652375 1370 PTAPEPHPTTsTDQPVTPKLTSRATrrKTNRSSVKTPKPVEPAASdlePFTPTDQ-SVTPEAIAQGGQSKT 1439
Cdd:pfam05109 696 TSSPAPRPGT-TSQASGPGNSSTST--KPGEVNVTKGTPPKNATS---PQAPSGQkTAVPTVTSTGGKANS 760
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1036-1474 |
2.76e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 68.79 E-value: 2.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1036 TPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqiSTSTDQPVTPKPTSRTTRSRTNMSS 1115
Cdd:pfam05109 429 TTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAG---TTSGASPVTPSPSPRDNGTESKAPD 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1116 VKNPESTVPIApelPPSTSTEQPVTPEPTSRATrgrkNRSSGKTPETLVPTAPKlePSTSTDQPVTPEPTSQATRGRTNR 1195
Cdd:pfam05109 506 MTSPTSAVTTP---TPNATSPTPAVTTPTPNAT----SPTLGKTSPTSAVTTPT--PNATSPTPAVTTPTPNATIPTLGK 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1196 SSvktpetvvPTAPELQPSTSTDQPVTPEPTSQA-TRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGR 1274
Cdd:pfam05109 577 TS--------PTSAVTTPTPNATSPTVGETSPQAnTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRP 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1275 KNRSSVKTPETVVPAAPELqPSTSTDQPVTPEPTSRATRGRTNRSSVKTPesivpiAPELQPSTsrnqlvtpepTSRATR 1354
Cdd:pfam05109 649 SSISETLSPSTSDNSTSHM-PLLTSAHPTGGENITQVTPASTSTHHVSTS------SPAPRPGT----------TSQASG 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1355 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKL---TSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAI 1431
Cdd:pfam05109 712 PGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTavpTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDYGGDSTTPRT 791
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1034652375 1432 AQGGQSKTLRSSTVRAMPVPTTPefQSPVTTDQPISP-EPITQP 1474
Cdd:pfam05109 792 RYNATTYLPPSTSSKLRPRWTFT--SPPVTTAQATVPvPPTSQP 833
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
859-1266 |
4.44e-11 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 68.02 E-value: 4.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 859 PKPKIRTRKSSRMTPFPAT---SAAPEPHPSTST------AQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPS-- 927
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKvifSKAPESTTTSPTlnttgfAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTpa 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 928 --TSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTAlelQPSTSTDRPVTSEPTSQATRGRKNRSS----VKTPepvVP 1001
Cdd:pfam05109 480 gtTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTP---TPNATSPTPAVTTPTPNATSPTLGKTSptsaVTTP---TP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1002 TAPELQPSTSTDQPVTSEPTYQATrgrKNRSSVKTPEP--VVPTAPELRPSTSTDRPVTPKPTSR---TTRSRTNMSSVK 1076
Cdd:pfam05109 554 NATSPTPAVTTPTPNATIPTLGKT---SPTSAVTTPTPnaTSPTVGETSPQANTTNHTLGGTSSTpvvTSPPKNATSAVT 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1077 TPETVVPTAPELQIS---TSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEP------TSRA 1147
Cdd:pfam05109 631 TGQHNITSSSTSSMSlrpSSISETLSPS-TSDNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPaprpgtTSQA 709
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1148 TRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPV---TPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTS-TDQPVTP 1223
Cdd:pfam05109 710 SGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSgqkTAVPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDyGGDSTTP 789
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1034652375 1224 EPTSQATRGRTDRSSVK-TPETVVPTAPELQASASTDQPVTSEP 1266
Cdd:pfam05109 790 RTRYNATTYLPPSTSSKlRPRWTFTSPPVTTAQATVPVPPTSQP 833
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1106-1492 |
6.96e-11 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 66.91 E-value: 6.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1106 TTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTStdqPVTPEPT 1185
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSS---PSSAAQS 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1186 SQATRGRTNRSSVKTPETVVPTAP-ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTS 1264
Cdd:pfam17823 130 LPAAIAALPSEAFSAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1265 EPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSR-ATRGRTNRSSVKTPESIVPIAPELQPST---SR 1340
Cdd:pfam17823 210 RGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATlAAAAGTVASAAGTINMGDPHARRLSPAKhmpSD 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1341 NQLVTPEPTSRAtRCRTNRSSVKTPEPVVPTAPEPHPTtstdqpvtpkltsratrrktnrssvktpkpvePAASDLEPFT 1420
Cdd:pfam17823 290 TMARNPAAPMGA-QAQGPIIQVSTDQPVHNTAGEPTPS--------------------------------PSNTTLEPNT 336
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034652375 1421 PTDQSVTPEAIAQGGQSKTLRSStvrAMPVPTTPEFQSPVTTdqpiSPEPITQPSCIKRQRAAGNPGSLAAP 1492
Cdd:pfam17823 337 PKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVE----ATSPTTQPSPLLPTQGAAGPGILLAP 401
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1229-1677 |
7.09e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 68.04 E-value: 7.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1229 ATRGRTDRSSVKTPETVVPTAPELQASAS-TDQPVTSEPTSRT---TRGRKNRSSVKTPETVVPAAPELQPSTsTDQPV- 1303
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAPAIlPDEPVGEPVHPRMltwIRGLEELASDDAGDPPPPLPPAAPPAA-PDRSVp 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1304 ----TPEPTSRATRGRTNRSSVKtPESIVPIAPELQPSTSRNQLvTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTT 1379
Cdd:PHA03247 2570 pprpAPRPSEPAVTSRARRPDAP-PQSARPRAPVDDRGDPRGPA-PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1380 STDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP-FTPTDQSVTPEA--IAQGGQSKTLRSSTVRAMPVPTTPEF 1456
Cdd:PHA03247 2648 PPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRaARPTVGSLTSLAdpPPPPPTPEPAPHALVSATPLPPGPAA 2727
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1457 ---QSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLE-PKSQASRNQRWGAVRAAESLTAIPEPASP 1532
Cdd:PHA03247 2728 arqASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgPPRRLTRPAVASLSESRESLPSPWDPADP 2807
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1533 QLLETPIHASQIQKVEPAGRSRFTPELQPKAS-----------------------QSRKRSLATMDSPPHQKQPQRGEVS 1589
Cdd:PHA03247 2808 PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPppppgppppslplggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLA 2887
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1590 QKTViiKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAVLALG 1669
Cdd:PHA03247 2888 RPAV--SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLG 2965
|
....*...
gi 1034652375 1670 GSLAGSAA 1677
Cdd:PHA03247 2966 ALVPGRVA 2973
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
746-1230 |
7.97e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.66 E-value: 7.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 746 PPQELGPSHCSFQTTGLLNCKMPPAEKASRIRAAEKVSRgdqeSPDACLPPTVPEAPAPPQKPlnsqsqkhlapppllsp 825
Cdd:PHA03247 2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR----PRRARRLGRAAQASSPPQRP----------------- 2683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 826 LLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPS-TSTAQPVTPkptsqaTRS 904
Cdd:PHA03247 2684 RRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVpAGPATPGGP------ARP 2757
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 905 RTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQAT 984
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 985 RGRKNRSSVKTPEP----VVPTAPelqpsTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPK 1060
Cdd:PHA03247 2838 APPPPPGPPPPSLPlggsVAPGGD-----VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQ 2912
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1061 PTSR-TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPV 1139
Cdd:PHA03247 2913 APPPpQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASS 2992
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1140 TPEPTSRATRGRKNRSSGKTPEtlVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQ-PSTSTD 1218
Cdd:PHA03247 2993 TPPLTGHSLSRVSSWASSLALH--EETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHdPFAHEP 3070
|
490
....*....|..
gi 1034652375 1219 QPVTPEPTSQAT 1230
Cdd:PHA03247 3071 DPATPEAGARES 3082
|
|
| FHA |
pfam00498 |
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif. |
76-131 |
1.20e-10 |
|
FHA domain; The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.
Pssm-ID: 459831 [Multi-domain] Cd Length: 66 Bit Score: 58.74 E-value: 1.20e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034652375 76 VVGRMPDCSVALPFPSISKQHAEIEILAwDKAPILRDCGSLNGT-----QILRPPKVLSPG 131
Cdd:pfam00498 2 TIGRSPDCDIVLDDPSVSRRHAEIRYDG-GGRFYLEDLGSTNGTfvngqRLGPEPVRLKDG 61
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
867-1305 |
3.32e-10 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 64.60 E-value: 3.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 867 KSSRMTPFPATSAAPEPHPSTstaqpvtpKPTSQATRSRTNRSSVKTPEpvvptapelqpSTSTDQPVTSEPTSQVTRGR 946
Cdd:pfam17823 53 KSSEQ*NFCAATAAPAPVTLT--------KGTSAAHLNSTEVTAEHTPH-----------GTDLSEPATREGAADGAASR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 947 ----KSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrknrSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1022
Cdd:pfam17823 114 alaaAASSSPSSAAQSLPAAIAALPSEAFSAPRAAACRANASAA----PRAAIAAASAPHAASPAPRTAASSTTAASSTT 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1023 QATRGrKNRSSVKTPEPVVPTAPELRPSTSTdrpVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKP 1102
Cdd:pfam17823 190 AASSA-PTTAASSAPATLTPARGISTAATAT---GHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVAS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1103 TSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPeTLVPTAPKLEPSTSTDQPVTP 1182
Cdd:pfam17823 266 AAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTN 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1183 EPTSQATRGRTNRSSVkTPETVVPTA--PELQPSTSTDQPvTPEPTSQATRGRTdrssvktpetvVPTAPELQASASTDQ 1260
Cdd:pfam17823 345 LAVVTTTKAQAKEPSA-SPVPVLHTSmiPEVEATSPTTQP-SPLLPTQGAAGPG-----------ILLAPEQVATEATAG 411
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1034652375 1261 PVTSEPTSRTTRGRKnrssvktpetvVPAAPELQPSTS------TDQPVTP 1305
Cdd:pfam17823 412 TASAGPTPRSSGDPK-----------TLAMASCQLSTQgqylvvTTDPLTP 451
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1080-1468 |
1.11e-09 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 63.06 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1080 TVVPTAP-ELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTV-PIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSG 1157
Cdd:pfam17823 63 ATAAPAPvTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAAdGAASRALAAAASSSPSSAAQSLPAAIAALPSEAF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1158 KTPETLVPTAP-KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPST--STDQPVTPEPTSQATRGRT 1234
Cdd:pfam17823 143 SAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSapATLTPARGISTAATATGHP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1235 DRSSVKTP-ETVVPTAPELQASASTDQPVTSepTSRTTRGRKNRSSVKTPETVVPAAPELQPSTST---DQPVTPEPTSR 1310
Cdd:pfam17823 223 AAGTALAAvGNSSPAAGTVTAAVGTVTPAAL--ATLAAAAGTVASAAGTINMGDPHARRLSPAKHMpsdTMARNPAAPMG 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1311 A-TRGRTNRSSVKTPesIVPIAPELQPSTSRNQLVTPEPTSRATRCRT--NRSSVKTPEPVVPTAPEPH----PTTSTDQ 1383
Cdd:pfam17823 301 AqAQGPIIQVSTDQP--VHNTAGEPTPSPSNTTLEPNTPKSVASTNLAvvTTTKAQAKEPSASPVPVLHtsmiPEVEATS 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1384 PVTPKLTSRATRRKTNRSSVKTPKPVEPAAsdlepfTPTDQSVTPEAIAQGGqSKTLRSSTVRampvPTTpEFQSPVTTD 1463
Cdd:pfam17823 379 PTTQPSPLLPTQGAAGPGILLAPEQVATEA------TAGTASAGPTPRSSGD-PKTLAMASCQ----LST-QGQYLVVTT 446
|
....*
gi 1034652375 1464 QPISP 1468
Cdd:pfam17823 447 DPLTP 451
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
875-1428 |
1.36e-09 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 63.57 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 875 PATSAAPEPHPSTSTAQPVTPKPTSQAtrsrtnrssVKTPEPVVPTAPE---LQPSTSTDQPVTSEPTSQVTRGRKSRSS 951
Cdd:PRK10263 339 PVTQTPPVASVDVPPAQPTVAWQPVPG---------PQTGEPVIAPAPEgypQQSQYAQPAVQYNEPLQQPVQPQQPYYA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 952 VKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGrkNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNR 1031
Cdd:PRK10263 410 PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAG--NAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQ 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1032 SSVKtPEPVVPTAPELRPSTSTDRPVtpkpTSRTTRSRTNMSS--------VKTPETVVPTAPELqiSTSTDQPVTPKPT 1103
Cdd:PRK10263 488 PVVE-PEPVVEETKPARPPLYYFEEV----EEKRAREREQLAAwyqpipepVKEPEPIKSSLKAP--SVAAVPPVEAAAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1104 SRTTRSRTNMSSVKNPESTVPIAPELPPSTSTeqpvTPEPTSRATRG----RKNRSSGKTPETLVPTAPKLePStstdQP 1179
Cdd:PRK10263 561 VSPLASGVKKATLATGAAATVAAPVFSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QR 631
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1180 VTPEPTSQATRGRTNRSSVKTPETVVPTAPE---LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASA 1256
Cdd:PRK10263 632 AAEEKAREAQRNQYDSGDQYNDDEIDAMQQDelaRQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRY 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1257 STDQPVTSEPTSRTTRgrkNRSSVKTPETVVPAAPELQPS-----TSTDQPVTPEPTSRATRGRTNRSSVKTPESivPIA 1331
Cdd:PRK10263 712 SGEQPAGANPFSLDDF---EFSPMKALLDDGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQ--PVA 786
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1332 PELQPSTSRnQLVTPEPTSRATRcRTNRSSVKTPEPVVPTAPEPhPTTSTDQPVTPKLTSRATRRKTNRSSVKTP--KPV 1409
Cdd:PRK10263 787 PQPQYQQPQ-QPVAPQPQYQQPQ-QPVAPQPQYQQPQQPVAPQP-QYQQPQQPVAPQPQDTLLHPLLMRNGDSRPlhKPT 863
|
570
....*....|....*....
gi 1034652375 1410 EPAASdLEPFTPTDQSVTP 1428
Cdd:PRK10263 864 TPLPS-LDLLTPPPSEVEP 881
|
|
| BRCT_BRC1_like_rpt6 |
cd18439 |
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) ... |
1732-1829 |
2.54e-09 |
|
sixth (C-terminal) BRCT domain of Schizosaccharomyces pombe BRCT-containing protein 1 (BRC1) and similar proteins; Schizosaccharomyces pombe BRC1 is required for mitotic fidelity, specifically in the G2 phase of the cell cycle. It plays a role in chromatin organization. The family also includes Cryptococcus neoformans DNA ligase 4 (LIG4, also known as DNA ligase IV or polydeoxyribonucleotide synthase [ATP] 4), which is involved in dsDNA break repair, and plays a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologus end-joining. Members in this family contains six BRCT domains. This family corresponds to the sixth repeat.
Pssm-ID: 349392 Cd Length: 116 Bit Score: 56.54 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1732 EKNFGFSLQDALSRARERR--LLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPSMPRSYKP--------QRVVITCPQD 1801
Cdd:cd18439 1 EKKYGCTLAESLARAKANKgkLLKGYTVYLTPKVKGGVETFKSIVEANGGICNLLRAAKGKLgdgiaekgPVVLISTTKE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1034652375 1802 ------------FPHCSIPLRvglpllSPEFLLTGVLKQE 1829
Cdd:cd18439 81 kklwpkflknarEGGKEPRVY------STDWLLDVVLRQE 114
|
|
| BRCT |
cd00027 |
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The ... |
1649-1712 |
1.63e-08 |
|
C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains; The BRCT (BRCA1 C-terminus) domain is found within many DNA damage repair and cell cycle checkpoint proteins. BRCT domains interact with each other forming homo/hetero BRCT multimers, but are also involved in BRCT-non-BRCT interactions and interactions within DNA strand breaks. BRCT tandem repeats bind to phosphopeptides; it has been shown that the repeats in human BRCA1 bind specifically to pS-X-X-F motifs, mediating the interaction between BRCA1 and the DNA helicase BACH1, or BRCA1 and CtIP, a transcriptional corepressor. It is assumed that BRCT repeats play similar roles in many signaling pathways associated with the response to DNA damage.
Pssm-ID: 349339 [Multi-domain] Cd Length: 68 Bit Score: 52.75 E-value: 1.63e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034652375 1649 PKVLFTGVVDARGE---RAVLALGGSLAGS-AAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQS 1712
Cdd:cd00027 1 LVICFSGLDDEEREelkKLIEALGGKVSESlSSKVTHLIAKSPSGEKYYLAALAWGIPIVSPEWLLDC 68
|
|
| FHA |
smart00240 |
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear ... |
76-121 |
2.84e-08 |
|
Forkhead associated domain; Found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain.
Pssm-ID: 214578 [Multi-domain] Cd Length: 52 Bit Score: 51.41 E-value: 2.84e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 1034652375 76 VVGRMP-DCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQI 121
Cdd:smart00240 2 TIGRSSeDCDIQLDGPSISRRHAVIVYDGGGRF-YLIDLGSTNGTFV 47
|
|
| BRCT_TopBP1_rpt7 |
cd17738 |
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA ... |
1649-1716 |
1.04e-07 |
|
seventh BRCT domain of DNA topoisomerase 2-binding protein 1; TopBP1, also termed DNA topoisomerase II-beta-binding protein 1, or DNA topoisomerase II-binding protein 1, functions in DNA replication and damage response. It binds double-stranded DNA breaks and nicks as well as single-stranded DNA. TopBP1 contains six copies of BRCT domain. The family corresponds to the seventh BRCT domain. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is missing in this group.
Pssm-ID: 349370 [Multi-domain] Cd Length: 75 Bit Score: 50.64 E-value: 1.04e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034652375 1649 PKVLFTGVVDArgERA-----VLALGGSLAGSA---AEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1716
Cdd:cd17738 2 PVFLLSGFSED--EKKelisiIEKLGGKVLDSDefdPKCTHLICGKPSRSEKFLAACAAGKWILHPSYIEASAKAG 75
|
|
| FHA_DgcB-like |
cd22682 |
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB ... |
59-152 |
1.16e-07 |
|
forkhead associated (FHA) domain found in Bdellovibrio bacteriovorus GGDEF domain protein DgcB and similar proteins; DgcB is a GGDEF enzyme that produces cyclic-di-GMP in response to an unknown stimulus. It appends the C-terminal GGDEF enzymatic domain with an N-terminal forkhead-associated (FHA) domain that acts as a consensus phosphopeptide sensor. The GGDEF and sensory FHA domains form an asymmetrical dimer.
Pssm-ID: 438734 [Multi-domain] Cd Length: 96 Bit Score: 51.37 E-value: 1.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 59 SGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAwdKAPILRDCGSLNGTQIlrPPKVLSPGVSHRLRD 138
Cdd:cd22682 6 IGPPGVGKQFPITESTIVIGRSVESQVQIDDDSVSRYHAKLAVNP--SAVSIIDLGSTNGTIV--NGKKIPKLASCDLQN 81
|
90
....*....|....
gi 1034652375 139 QELILFADLLCQYH 152
Cdd:cd22682 82 GDQIKIGNTIFKFH 95
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
1077-1380 |
1.21e-07 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 56.93 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1077 TPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPeSTVPIAPELPPSTSTEQPV---TPEPTSRATRGRKN 1153
Cdd:TIGR00927 103 TPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRALNHYISTSGRQRVksyTPKPRGEVKSSSPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1154 RSSGK----TPETLVPTAPKLEPSTSTDQPvtpeptsqATRGRTNRSSVKTPETvvpTAPELQPSTSTDQPVTPEPTSQA 1229
Cdd:TIGR00927 182 QTREKvrkyTPSPLGRMVNSYAPSTFMTMP--------RSHGITPRTTVKDSEI---TATYKMLETNPSKRTAGKTTPTP 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1230 TRGRTDRSS---VKTPETVVPTAPELQASAST-DQPVTSEPTSRTT-RGRKNRSSVKTPETVV----PAAPELQPSTSTD 1300
Cdd:TIGR00927 251 LKGMTDNTPtflTREVETDLLTSPRSVVEKNTlTTPRRVESNSSTNhWGLVGKNNLTTPQGTVlehtPATSEGQVTISIM 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1301 QPVTPEPTSRATRGRTNRS-SVKTPESIVPIAP------ELQPSTSRNQLVTPE----PTSRATRCrtnrsSVKTPEPVV 1369
Cdd:TIGR00927 331 TGSSPAETKASTAAWKIRNpLSRTSAPAVRIASatfrglEKNPSTAPSTPATPRvravLTTQVHHC-----VVVKPAPAV 405
|
330
....*....|.
gi 1034652375 1370 PTAPEPHPTTS 1380
Cdd:TIGR00927 406 PTTPSPSLTTA 416
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1027-1435 |
1.25e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 57.10 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1027 GRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRT 1106
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1107 TRSrtnMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRgrknrSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTS 1186
Cdd:PHA03307 118 PPT---PPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGA-----SPAAVASDAASSRQAALPLSSPEETARAPSSP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1187 QATRGrTNRSSVKTPETVVPTAPELQPSTSTDQPVtPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1266
Cdd:PHA03307 190 PAEPP-PSTPPAAASPRPPRRSSPISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1267 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRatrgRTNRSSVKTPESIVPIAPELQPSTSRNQLVTP 1346
Cdd:PHA03307 268 RIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1347 EPTSRATRCRTNRSSVKTPEPVvPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvEPAASDLEPFTPTDQSV 1426
Cdd:PHA03307 344 GPSPSRSPSPSRPPPPADPSSP-RKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAT-GRFPAGRPRPSPLDAGA 421
|
....*....
gi 1034652375 1427 TPEAIAQGG 1435
Cdd:PHA03307 422 ASGAFYARY 430
|
|
| BRCT_microcephalin_rpt2 |
cd17736 |
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage ... |
1651-1719 |
1.31e-07 |
|
second BRCT domain of microcephalin and similar proteins; Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Microcephalin contains three BRCT repeats. This family corresponds to the second repeat.
Pssm-ID: 349368 [Multi-domain] Cd Length: 76 Bit Score: 50.67 E-value: 1.31e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034652375 1651 VLFTGVVDARGE---RAVLALGG-SLAGSAAE-ASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFL 1719
Cdd:cd17736 3 LVMTSVHSEEQElleSVVKKLGGfRVEDSVTEkTTHVVVGSPRRTLNVLLGIARGCWILSPDWVLESLEAGKWL 76
|
|
| BRCT_nibrin |
cd17741 |
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage ... |
1664-1715 |
1.47e-07 |
|
BRCT domain of nibrin and similar proteins; Nibrin (NBN), also termed Nijmegen breakage syndrome protein 1 (NBS1), or cell cycle regulatory protein p95, is a novel DNA double-strand break repair protein that is mutated in Nijmegen breakage syndrome. It is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The BRCT (Breast Cancer Suppressor Protein BRCA1, carboxy-terminal) domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo/hetero BRCT multimers, BRCT-non-BRCT interactions, and interactions within DNA strand breaks. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is absent in this group.
Pssm-ID: 349372 [Multi-domain] Cd Length: 74 Bit Score: 50.29 E-value: 1.47e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1034652375 1664 AVLALGGSLAGSAAEAS-HLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKA 1715
Cdd:cd17741 21 IIAKLGGKVVNEWTEECtHLVMSKIKVTVKVICALISGKPIVTPEYLDALLEA 73
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
974-1523 |
1.80e-07 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 56.63 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 974 PVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSeptYQATRGrknrssVKTPEPVVPTAPELRPstst 1053
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVA---WQPVPG------PQTGEPVIAPAPEGYP---- 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1054 drpvtPKPTSRTTRSRTNMSSVKtpetvvPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPST 1133
Cdd:PRK10263 382 -----QQSQYAQPAVQYNEPLQQ------PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1134 STEQPVTPEPTSRATrgrknrssgKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPT-APELQ 1212
Cdd:PRK10263 451 EQQSTFAPQSTYQTE---------QTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARERE 521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1213 PSTSTDQPVtPEPtsqatrgrtdrssVKTPETVVPTAPELQASASTdqPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPE 1292
Cdd:PRK10263 522 QLAAWYQPI-PEP-------------VKEPEPIKSSLKAPSVAAVP--PVEAAAAVSPLASGVKKATLATGAAATVAAPV 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1293 LQPSTSTdqpvTPEPTSRATRG----RTNRSSVKTPESIVPIAPELqPStsrnQLVTPEPTSRATRCRTNRSSVKTPEPV 1368
Cdd:PRK10263 586 FSLANSG----GPRPQVKEGIGpqlpRPKRIRVPTRRELASYGIKL-PS----QRAAEEKAREAQRNQYDSGDQYNDDEI 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1369 VPTAPE----------------------PHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQ-- 1424
Cdd:PRK10263 657 DAMQQDelarqfaqtqqqrygeqyqhdvPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKAll 736
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1425 -----------SVTPEAIAQgGQSKTLRSSTVRAMPVPTTPEFQSPvttDQPISPEPITQ--PSCIKRQRAAGNPGSLAA 1491
Cdd:PRK10263 737 ddgpheplftpIVEPVQQPQ-QPVAPQQQYQQPQQPVAPQPQYQQP---QQPVAPQPQYQqpQQPVAPQPQYQQPQQPVA 812
|
570 580 590
....*....|....*....|....*....|...
gi 1034652375 1492 P-IDHKPCSAPLEPKSQASRNQRWGAVRAAESL 1523
Cdd:PRK10263 813 PqPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTL 845
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
772-1132 |
2.18e-07 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 56.24 E-value: 2.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 772 KASRIRAAEKVSRG--DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKT----RQDGSQEA 845
Cdd:PTZ00449 568 KPSKIPTLSKKPEFpkDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRppppQRPSSPER 647
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 846 PEAPLS--SELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPe 923
Cdd:PTZ00449 648 PEGPKIikSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLP- 726
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 924 lqpstsTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTsqatrgRKNRSSVKTPEPVVPTA 1003
Cdd:PTZ00449 727 ------RDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEF------KEEDIHAETGEPDEAMK 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1004 PELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEpvVPTAPELRPSTSTDRPVTPKptsrTTRSRTNMSSVKTPETVVP 1083
Cdd:PTZ00449 795 RPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTD--LESDAGRIAKDASGKIVKLK----RSKSFDDLTTVEEAEEMGA 868
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1034652375 1084 TAPELQIS---TSTD----QPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPS 1132
Cdd:PTZ00449 869 EARKIVVDddgTEADdedtHPPEEKHKSEVRRRRPPKKPSKPKKPSKPKKPKKPDS 924
|
|
| RTT107_BRCT_5 |
pfam16770 |
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of ... |
1668-1724 |
6.69e-07 |
|
Regulator of Ty1 transposition protein 107 BRCT domain; This is the fifth BRCT domain of regulator of Ty1 transposition protein 107 (RTT107). It is involved in binding phosphorylated histone H2A.
Pssm-ID: 465266 Cd Length: 91 Bit Score: 49.05 E-value: 6.69e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1668 LGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEY 1724
Cdd:pfam16770 33 LGIKIVQDPSKCNHLIAPKILRTEKFLCALAFAPYILSPDFITDCLKEGKLPDEEDY 89
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1130-1538 |
7.69e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.41 E-value: 7.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1130 PPSTSTEQPVTPeptsraTRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP 1209
Cdd:PHA03307 24 PPATPGDAADDL------LSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1210 ELQPSTSTDQPVTPEPTSqaTRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1289
Cdd:PHA03307 98 ASPAREGSPTPPGPSSPD--PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1290 APELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVV 1369
Cdd:PHA03307 176 LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENEC 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1370 PtAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSV-----KTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSS- 1443
Cdd:PHA03307 256 P-LPRPAPITLPTRIWEASGWNGPSSRPGPASSSsspreRSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSe 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1444 TVRAMPVPTTPEFQSPVTTDQPisPEPITQPSCIKRQRAAGNPGSLAAPIDHKPC----SAPLEPKSQASRNQRWGAVRA 1519
Cdd:PHA03307 335 SSRGAAVSPGPSPSRSPSPSRP--PPPADPSSPRKRPRPSRAPSSPAASAGRPTRrrarAAVAGRARRRDATGRFPAGRP 412
|
410
....*....|....*....
gi 1034652375 1520 AESLTAIPEPASPQLLETP 1538
Cdd:PHA03307 413 RPSPLDAGAASGAFYARYP 431
|
|
| FHA_Ki67 |
cd22673 |
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar ... |
53-146 |
9.42e-07 |
|
forkhead associated (FHA) domain found in proliferation marker protein Ki-67 and similar proteins; Ki-67, also called antigen identified by monoclonal antibody Ki-67, antigen KI-67, or antigen Ki67, acts as a biological surfactant to disperse mitotic chromosomes. It is required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Ki-67 binds DNA with a preference for supercoiled DNA and AT-rich DNA. It may also play a role in chromatin organization. Ki-67 contains an FHA domain at its N-terminus. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438725 [Multi-domain] Cd Length: 95 Bit Score: 48.75 E-value: 9.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 53 GRLHIF--SGAHGPEkdFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKApILRDCGSLNGTQiLRPPKVLSP 130
Cdd:cd22673 1 GKLVVIkkDGTDGSR--FPLTKKSCTFGRDLSCDIRIQLPGVSREHCRIEVDENGKA-YLENLSTTNPTL-VNGKAIEKS 76
|
90
....*....|....*.
gi 1034652375 131 gvsHRLRDQELILFAD 146
Cdd:cd22673 77 ---AELKDGDVITIGG 89
|
|
| FHA_FhaA-like |
cd22668 |
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing ... |
62-121 |
1.53e-06 |
|
forkhead associated (FHA) domain found in Mycobacterium tuberculosis FHA domain-containing protein FhaA and similar proteins; FhaA regulates cell growth and peptidoglycan synthesis by binding to MviN. It may inhibit the late stages of peptidoglycan synthesis. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438720 [Multi-domain] Cd Length: 91 Bit Score: 47.85 E-value: 1.53e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034652375 62 HGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIeilAWD-KAPILRDCGSLNGTQI 121
Cdd:cd22668 7 DGSGRVYQLREGSNIIGRGSDADFRLPDTGVSRRHAEI---RWDgQVAHLTDLGSTNGTTV 64
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1014-1594 |
1.75e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 53.17 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1014 QPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnMSSVKTPETVVPTAPElqisTS 1093
Cdd:PRK10263 314 APITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQP---------VPGPQTGEPVIAPAPE----GY 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1094 TDQPVTPKPTSRttrsrtnmssvKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPS 1173
Cdd:PRK10263 381 PQQSQYAQPAVQ-----------YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1174 TSTDQPVTPEPTSQATRgrtnrssvKTPETVVPTAPELQPStSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT-APEL 1252
Cdd:PRK10263 450 EEQQSTFAPQSTYQTEQ--------TYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKrARER 520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1253 QASASTDQPVtSEPtsrttrgrknrssVKTPETVVPAAPelQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1332
Cdd:PRK10263 521 EQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1333 ELQPSTSRnqlvTPEPtsratrcrtnrssvKTPEPVVPTAPEPH----PTTSTDQPVTPKLTSRATRRKTNRSSVKTPKP 1408
Cdd:PRK10263 585 VFSLANSG----GPRP--------------QVKEGIGPQLPRPKrirvPTRRELASYGIKLPSQRAAEEKAREAQRNQYD 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1409 VEPAASDLEpftpTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEfqspvTTDQPISPEPITQPSCIKRQRAAG---- 1484
Cdd:PRK10263 647 SGDQYNDDE----IDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAE-----DADAAAEAELARQFAQTQQQRYSGeqpa 717
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1485 --NPGSLA----APID-------HKPCSAP-LEPKSQASRNQRWGAVRAAESLTAIPEPA--SPQLLETPIHASQIQKVE 1548
Cdd:PRK10263 718 gaNPFSLDdfefSPMKallddgpHEPLFTPiVEPVQQPQQPVAPQQQYQQPQQPVAPQPQyqQPQQPVAPQPQYQQPQQP 797
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1034652375 1549 PAGRSRFTPELQPKASQSRKRSLATMDSPP---HQKQPQRGEVSQKTVI 1594
Cdd:PRK10263 798 VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQPQDTLL 846
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
927-1285 |
1.98e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 53.25 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 927 STSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEP----VVPT 1002
Cdd:PHA03307 61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPdlseMLRP 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1003 APELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRtnmssvktpetvv 1082
Cdd:PHA03307 141 VGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPP------------- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1083 PTAPELQISTSTDQPVTPKpTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPET 1162
Cdd:PHA03307 208 RRSSPISASASSPAPAPGR-SAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPAS 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1163 LVPTAPKLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1240
Cdd:PHA03307 287 SSSSPRERSPSPSPSSPGSGPAPSSPRasSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPR 366
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1034652375 1241 TPETVVPTAPELQASAST-----------DQPVTSEPTSRTTRGRKNRSSVKTPET 1285
Cdd:PHA03307 367 KRPRPSRAPSSPAASAGRptrrraraavaGRARRRDATGRFPAGRPRPSPLDAGAA 422
|
|
| FHA_PP2C70-like |
cd22678 |
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 ... |
77-143 |
4.01e-06 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana protein phosphatase 2C 70 (AtPP2C70) and similar proteins; AtPP2C70, also called kinase-associated protein phosphatase, or protein ROOT ATTENUATED GROWTH 1, dephosphorylates the serine/threonine receptor-like kinase RLK5. It may function as a signaling component in a pathway involving RLK5. It acts as a negative regulator of the CLAVATA1 signaling in plant development by binding and dephosphorylating CLAVATA1. It is also a component of a signaling pathway which mediates adaptation to NaCl stress. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438730 [Multi-domain] Cd Length: 102 Bit Score: 46.97 E-value: 4.01e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034652375 77 VGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQI-LRPPKVlsPGVSHRLRDQELIL 143
Cdd:cd22678 27 IGRIQRGDIALKDDEVSGKHARIEWNSTGSKWELVDLGSLNGTLVnGESISP--NGRPVVLSSGDVIT 92
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
795-1169 |
4.18e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 52.00 E-value: 4.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 795 PPTVPEAPA-PPQKPLNSQSQ-KHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAP-------EAPLSSEL-----EPFHPK 860
Cdd:PTZ00449 510 PPEGPEASGlPPKAPGDKEGEeGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPakehkpsKIPTLSKKpefpkDPKHPK 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 861 PKIRTRKSSRmtpfPATSAAPEPHPSTSTAQPVT-PKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTS-EP 938
Cdd:PTZ00449 590 DPEEPKKPKR----PRSAQRPTRPKSPKLPELLDiPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSpKP 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 939 TSQVTRGRK-----SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGR-------KNRSSVKTPePVVPTAPEL 1006
Cdd:PTZ00449 666 PFDPKFKEKfyddyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRplppklpRDEEFPFEP-IGDPDAEQP 744
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1007 QPSTSTDQPVTSEPTYQATRGRKNRSSV-----KTP----EPVVPTAPELRPSTST---DRPVTPKPTSRTTRSRTNMSS 1074
Cdd:PTZ00449 745 DDIEFFTPPEEERTFFHETPADTPLPDIlaeefKEEdihaETGEPDEAMKRPDSPSeheDKPPGDHPSLPKKRHRLDGLA 824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1075 VKTPEtvVPTAPELQISTSTDQPVTPKptsrttRSRTNmssvkNPESTVPIAPELPPSTS--------TE------QPVT 1140
Cdd:PTZ00449 825 LSTTD--LESDAGRIAKDASGKIVKLK------RSKSF-----DDLTTVEEAEEMGAEARkivvdddgTEaddedtHPPE 891
|
410 420
....*....|....*....|....*....
gi 1034652375 1141 PEPTSRATRGRKNRSSGKTPETLVPTAPK 1169
Cdd:PTZ00449 892 EKHKSEVRRRRPPKKPSKPKKPSKPKKPK 920
|
|
| FHA_Kanadaptin |
cd22677 |
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also ... |
76-137 |
5.34e-06 |
|
forkhead associated (FHA) domain found in kanadaptin and similar proteins; Kanadaptin, also called human lung cancer oncogene 3 protein (HLC-3), kidney anion exchanger adapter protein, or solute carrier family 4 anion exchanger member 1 adapter protein (SLC4A1AP), is a nuclear protein widely expressed in mammalian tissues. It was originally isolated as a kidney Cl-/HCO3- anion exchanger 1 (kAE1)-binding protein. It is a highly mobile nucleocytoplasmic shuttling and multilocalizing protein. Its role in mammalian cells remains unclear. It contains an FHA domain, which is a small phosphopeptide recognition module.
Pssm-ID: 438729 [Multi-domain] Cd Length: 106 Bit Score: 46.78 E-value: 5.34e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1034652375 76 VVGRMPDCSVALPFPSISKQHAeieILAWDKAPI-------LRDCGSLNGTQILRPPkvLSPGVSHRLR 137
Cdd:cd22677 25 VFGRLPGCDVVLEHPSISRYHA---VLQYRGDADdhdggfyLYDLGSTHGTFLNKQR--IPPKQYYRLR 88
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
889-1115 |
5.57e-06 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 50.96 E-value: 5.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 889 TAQPVTPKP-------TSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRS-SVKTPETVVP 960
Cdd:PRK13914 144 TSTPVAPTQevkkettTQQAAPAAETKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWAlSVKYGVSVQD 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 961 TALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVP--TAPELQPSTSTDQPVTSeptyqatrgrknRSSVKTPE 1038
Cdd:PRK13914 224 IMSWNNLSSSSIYVGQKLAIKQTANTATPKAEVKTEAPAAEkqAAPVVKENTNTNTATTE------------KKETTTQQ 291
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1039 PVVPTAPelrpsTSTDRPvTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSS 1115
Cdd:PRK13914 292 QTAPKAP-----TEAAKP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNS 362
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1203-1506 |
6.46e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 51.11 E-value: 6.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1203 TVVPTAP-ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE-TVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSV 1280
Cdd:pfam17823 63 ATAAPAPvTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREgAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAF 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1281 KTPETVVPAAP-ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNR 1359
Cdd:pfam17823 143 SAPRAAACRANaSAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHP 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1360 SSVKTPEPVVPTAPEPHPTTSTDQPVTP-KLTSRATRRKTNRSSVKTPKPVEPAASDLEP--FTPTDQSVTPEAIAQGGQ 1436
Cdd:pfam17823 223 AAGTALAAVGNSSPAAGTVTAAVGTVTPaALATLAAAAGTVASAAGTINMGDPHARRLSPakHMPSDTMARNPAAPMGAQ 302
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034652375 1437 SKTLRSSTVRAMPVPTT---PEFQSPVTTDQPISPEPITQPS---CIKRQRAAGNPGSLAAPIDHKPCSAPLEPKS 1506
Cdd:pfam17823 303 AQGPIIQVSTDQPVHNTagePTPSPSNTTLEPNTPKSVASTNlavVTTTKAQAKEPSASPVPVLHTSMIPEVEATS 378
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
998-1432 |
7.12e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 51.23 E-value: 7.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 998 PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAP----ELRPS---TSTDRPVTPKPTsrttrsrt 1070
Cdd:PTZ00449 514 PEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPgpakEHKPSkipTLSKKPEFPKDP-------- 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1071 nmssvKTPETvvPTAPElqistSTDQPVTP-KPTSRttrsrtnmSSVKNPEST-VPIAPELPPSTSTeqPVTPEPTSRAT 1148
Cdd:PTZ00449 586 -----KHPKD--PEEPK-----KPKRPRSAqRPTRP--------KSPKLPELLdIPKSPKRPESPKS--PKRPPPPQRPS 643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1149 RGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSq 1228
Cdd:PTZ00449 644 SPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLP- 722
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1229 ATRGRTDRSSVKTPETvvPTAPElqasaSTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPept 1308
Cdd:PTZ00449 723 PKLPRDEEFPFEPIGD--PDAEQ-----PDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEEDIHAETGEPDEA--- 792
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1309 srATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR---------CRTNRSSVKTPEPVVPTAPEPHP-- 1377
Cdd:PTZ00449 793 --MKRPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDLESDAGRiakdasgkiVKLKRSKSFDDLTTVEEAEEMGAea 870
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1378 ---------TTSTDQPVTP---KLTSRATRRKTNRSSVKTPKPVEPAasdlEPFTPtDQSVTPEAIA 1432
Cdd:PTZ00449 871 rkivvdddgTEADDEDTHPpeeKHKSEVRRRRPPKKPSKPKKPSKPK----KPKKP-DSAFIPSIIA 932
|
|
| BRCT_p53bp1_rpt1 |
cd17745 |
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, ... |
1682-1716 |
7.61e-06 |
|
first (central) BRCT domain in p53-binding protein 1 (p53BP1) and similar proteins; p53BP1, also termed 53BP1, or TP53-binding protein 1 (TP53BP1) , is a double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. TP53BP1 contains two tandem BRCT repeats. This family also includes Schizosaccharomyces pombe Crb2, which is a checkpoint mediator required for the cellular response to DNA damage. This model corresponds to the first BRCT domain.
Pssm-ID: 349376 [Multi-domain] Cd Length: 99 Bit Score: 46.15 E-value: 7.61e-06
10 20 30
....*....|....*....|....*....|....*
gi 1034652375 1682 LVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAG 1716
Cdd:cd17745 64 LIADSPSRTPKYLQALALGIPCVSHKWILDCIEAG 98
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1171-1298 |
7.74e-06 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 51.25 E-value: 7.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1171 EPSTSTDQPVTPEPTSQATrgrtnrssvkTPETVVPTAPELQPSTsTDQPVTPEPTSQATRGrTDRSSVKTPETVVPTAP 1250
Cdd:NF033875 49 QPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKDT-TSQPTKVEEVASEKNG-AEQSSATPNDTTNAQQP 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1034652375 1251 ELQASAST-DQPVTSEPTSRTTRGRknrssvktPETVVPAAPELQPSTS 1298
Cdd:NF033875 117 TVGAEKSAqEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| FHA_PS1-like |
cd22691 |
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) ... |
76-119 |
9.15e-06 |
|
forkhead associated (FHA) domain found in Arabidopsis thaliana Protein PARALLEL SPINDLE 1 (PS1) and similar proteins; PS1 is an FHA domain-containing protein required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. It is not involved in female meiosis. Mutations in PS1 lead to the production of diploid pollen grains. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438743 [Multi-domain] Cd Length: 113 Bit Score: 46.26 E-value: 9.15e-06
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1034652375 76 VVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 119
Cdd:cd22691 32 VVGRHPDCDIVLDHPSISRFHLEIRIIPSRRKITLTDLSSVHGT 75
|
|
| FHA_ArnA-like |
cd22680 |
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing ... |
55-131 |
1.24e-05 |
|
forkhead associated (FHA) domain found in Sulfolobus Acidocaldarius FHA domain-containing protein ArnA and similar proteins; ArnA is an FHA domain-containing protein from Sulfolobus acidocaldarius that was shown to strongly interact with ArnB, a von Willebrand domain-containing protein. They act synergistically and negatively to modulate motility. ArnA is involved in regulating archaella expression in S. acidocaldarius. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438732 [Multi-domain] Cd Length: 96 Bit Score: 45.41 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 55 LHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQI-----LRPPKVLS 129
Cdd:cd22680 3 LEILSSPNLTGKKFPFDFSSVSIGRDPENVIVIPDPFVSRNHARITVD--SNEIYIEDLGSTNGTFVndfkrIKGPAKLH 80
|
..
gi 1034652375 130 PG 131
Cdd:cd22680 81 PN 82
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
777-1160 |
1.59e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 777 RAAEKVSRGDQESPDACLPPTVPEAPAP-PQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE 855
Cdd:PHA03307 46 DSAELAAVTVVAGAAACDRFEPPTGPPPgPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 856 PFHPkpkirtrkssrmTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTdqPVT 935
Cdd:PHA03307 126 PPPS------------PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS--PPA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 936 SEPTSQVTRGRKSRSSVKTPetvvptalELQPSTSTDRPVtSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQP 1015
Cdd:PHA03307 192 EPPPSTPPAAASPRPPRRSS--------PISASASSPAPA-PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1016 VTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRttrsRTNMSSVKTPETVVPTAPELQISTSTD 1095
Cdd:PHA03307 263 ITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSS----PRASSSSSSSRESSSSSTSSSSESSRG 338
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1096 QPVTPKPTSRT--TRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTP 1160
Cdd:PHA03307 339 AAVSPGPSPSRspSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
945-1313 |
1.63e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 945 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTyqA 1024
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSP--D 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1025 TRGRKNRSSVKTPEPVVPTAPELR---PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPElqistSTDQPVTPK 1101
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRpvgSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE-----TARAPSSPP 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1102 PTSRTTRSRTNMSSVKNPEStVPIAPELPPSTSTeqpvtPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVT 1181
Cdd:PHA03307 191 AEPPPSTPPAAASPRPPRRS-SPISASASSPAPA-----PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPIT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1182 PEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQAtrgRTDRSSVKTPETVvpTAPELQASASTDQP 1261
Cdd:PHA03307 265 LPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSP---RASSSSSSSRESS--SSSTSSSSESSRGA 339
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1034652375 1262 VTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATR 1313
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRAR 391
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
842-1188 |
1.76e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 49.99 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 842 SQEAPEAPLSSELEPFHPKPkirTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPePVVPTA 921
Cdd:TIGR00927 76 SSDPPKSSSEMEGEMLAPQA---TVGRDEATPSIAMENTPSPPRRTAKITPTTPKNNYSPTAAGTERVKEDTP-ATPSRA 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 922 PELQPSTSTDQPVTSepTSQVTRG-RKSRSSVKTPETVvptalelqpststdRPVTSEPtsqatRGRKNRSSVKTPEPVV 1000
Cdd:TIGR00927 152 LNHYISTSGRQRVKS--YTPKPRGeVKSSSPTQTREKV--------------RKYTPSP-----LGRMVNSYAPSTFMTM 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1001 PTAPELQP-STSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTD---------RPVTPKPTSRTTRSRT 1070
Cdd:TIGR00927 211 PRSHGITPrTTVKDSEITATYKMLETNPSKRTAGKTTPTPLKGMTDNTPTFLTREvetdlltspRSVVEKNTLTTPRRVE 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1071 NMSS-----------VKTPETVV----PTAPELQISTSTDQPVTPKptsrTTRSRTNMSSVKNPES-----TVPIAP--- 1127
Cdd:TIGR00927 291 SNSStnhwglvgknnLTTPQGTVlehtPATSEGQVTISIMTGSSPA----ETKASTAAWKIRNPLSrtsapAVRIASatf 366
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034652375 1128 ---ELPPSTSTEQPVTPEPTSRATRgRKNRSSGKTPETLVPTAPklEPS-TSTDQPVTPEPTSQA 1188
Cdd:TIGR00927 367 rglEKNPSTAPSTPATPRVRAVLTT-QVHHCVVVKPAPAVPTTP--SPSlTTALFPEAPSPSPSA 428
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
868-1175 |
2.96e-05 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 48.84 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 868 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPStSTDQPVTSEPTSQVTRGRK 947
Cdd:PHA03369 349 KTASLTAPSRVLAAAAKVAVIAAPQTHTGPADRQRPQRPDGIPYSVPARSPMTAYPPVPQ-FCGDPGLVSPYNPQSPGTS 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 948 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPT-SQATRGRKNRSSVKtpEPVVPTAPELQPSTSTDQPVTSEPTYQATR 1026
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQeHGHERKRKRGGELK--EELIETLKLVKKLKEEQESLAKELEATAHK 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1027 GRKNRSS--------VKTPEPVV---PTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVP----TAPELQIS 1091
Cdd:PHA03369 506 SEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSftstTLAAAAGQ 585
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1092 TSTDQPVTPKPTSRTTrsrTNMSSVKNPESTVpiAPELPPSTSTEQPvTPEPTSRATRGRKNRSSGKTpETLVPTAPKLE 1171
Cdd:PHA03369 586 GSDTAEALAGAIETLL---TQASAQPAGLSLP--APAVPVNASTPAS-TPPPLAPQEPPQPGTSAPSL-ETSLPQQKPVL 658
|
....
gi 1034652375 1172 PSTS 1175
Cdd:PHA03369 659 SKGA 662
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
875-1320 |
3.01e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 3.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 875 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSsvkt 954
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ---- 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 955 petvvPTALELQPSTSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPVTSE-PTYQATRGRKNRSS 1033
Cdd:PRK07764 466 -----PAPAPAAAPEPTAAPAPAPPAAPAP----------AAAPAAPAAPAAPAGADDAATLRERwPEILAAVPKRSRKT 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1034 --VKTPEPVVPtapELRPSTSTdrpvtpkPTSRTTRSRTNMSSVKTPETVVpTApelqISTSTDQPVTPKPTSRTTRSRT 1111
Cdd:PRK07764 531 waILLPEATVL---GVRGDTLV-------LGFSTGGLARRFASPGNAEVLV-TA----LAEELGGDWQVEAVVGPAPGAA 595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1112 NMSSVKNPESTVPI--APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQAT 1189
Cdd:PRK07764 596 GGEGPPAPASSGPPeeAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1190 RGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPePTSQATRGRTDRSSVKTpetvvpTAPELQASASTDQPVTSEPTSR 1269
Cdd:PRK07764 676 AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP-PAGQADDPAAQPPQAAQ------GASAPSPAADDPVPLPPEPDDP 748
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1034652375 1270 TTRGRKNRSSVKTPETVVPAAP--ELQPSTSTDQPVTPEPTSRATRGRTNRSS 1320
Cdd:PRK07764 749 PDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMAEDDAPSMDDEDRRDA 801
|
|
| FHA_MEK1-like |
cd22670 |
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine ... |
52-131 |
3.24e-05 |
|
forkhead associated (FHA) domain found in Saccharomyces cerevisiae meiosis-specific serine/threonine-protein kinase MEK1 and similar proteins; MEK1 (EC 2.7.11.1), also known as MRE4, is a meiosis-specific protein kinase required for chromosome synapsis and meiotic recombination. The recruitment and activation of MEK1 require the phosphorylation of the chromosome axis protein Hop1 at Thr318 (pT318), which is necessary for recognition by the MEK1 FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438722 [Multi-domain] Cd Length: 105 Bit Score: 44.53 E-value: 3.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 52 VGRLHIFSGAhGPEKDFPLHLGKNV-VGRMPDCSVALPFPSISKQHAEIEILAWDK--API--LRDCgSLNGTQI----- 121
Cdd:cd22670 1 VGKLEVSSPG-STDIVLPIYKNQVItIGRSPSCDIVINDPFVSRTHCRIYSVQFDEssAPLvyVEDL-SSNGTYLngkli 78
|
90
....*....|.
gi 1034652375 122 -LRPPKVLSPG 131
Cdd:cd22670 79 gRNNTVLLSDG 89
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
776-1068 |
8.22e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.86 E-value: 8.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 776 IRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEA--PLSSE 853
Cdd:PHA03307 100 PAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalPLSSP 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 854 LEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQP---VTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTST 930
Cdd:PHA03307 180 EETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASspaPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPR 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 931 DQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATrgrkNRSSVKTPEPVVPTAPELQPST 1010
Cdd:PHA03307 260 PAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR----ASSSSSSSRESSSSSTSSSSES 335
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1034652375 1011 STDQPVTSEPTYQATRGRKNRSSVKTPEPvVPTAPELRPSTSTDRPVTPKPTSRTTRS 1068
Cdd:PHA03307 336 SRGAAVSPGPSPSRSPSPSRPPPPADPSS-PRKRPRPSRAPSSPAASAGRPTRRRARA 392
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1126-1417 |
2.22e-04 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 45.82 E-value: 2.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1126 APELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP-KLEPSTSTDQPVTPEPTSQAT--RGRTNRSSVKTPE 1202
Cdd:pfam04747 189 APAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSES 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1203 TVVPTAPE--LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTsrTTRGRKNRSSV 1280
Cdd:pfam04747 269 ENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFV--TAKEEPKDEPA 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1281 KTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKT------PESIVPIAPELQPSTSRNQLVTPEPTSRATR 1354
Cdd:pfam04747 347 ETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESekvteqPVESAPAPPQVEQVVETTPPASENKKKNKKD 426
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034652375 1355 CRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLE 1417
Cdd:pfam04747 427 KKKSESEKAVEEPVQAAPSSKKPTADDNMDFLDFVTAKPDKSESVEEHIAAPMIVEPAHADEE 489
|
|
| FHA_AGGF1 |
cd22686 |
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 ... |
46-153 |
2.38e-04 |
|
forkhead associated (FHA) domain found in angiogenic factor with G patch and FHA domains 1 (AGGF1) and similar proteins; AGGF1, also called angiogenic factor VG5Q, or G patch domain-containing protein 7 (GPATC7), or vasculogenesis gene on 5q protein, is an angiogenic factor involved in vascular development, angiogenesis, specification of hemangioblasts, and differentiation of veins. It promotes angiogenesis and the proliferation of endothelial cells. It inhibits inflammatory effect and preserve vascular integrity in non-nervous system diseases. Mutated AGGF1 causes susceptibility to Klippel-Trenaunay syndrome, a vascular disorder. Increased AGGF1 expression is associated with tumor angiogenesis. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438738 [Multi-domain] Cd Length: 123 Bit Score: 42.65 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 46 RCNVEPVGRLHIFS--GAhgpekdfplhlgknVVGRMPDCSVALPFP--SISKQHAEIEILAWDKAPILRDCGS-----L 116
Cdd:cd22686 11 ESPSLQVGSLFIVTatGA--------------TIGREKDHGHTIRIPelGVSKFHAEIYYDDDEQSYTIVDLGSqngtyL 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 1034652375 117 NGTQILRPPKVLSP-GVSHrlRDQELILFADLLCQYHR 153
Cdd:cd22686 77 NGVRISQPKEKSDPyPLTH--GDELKIGETTLLFHIHP 112
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
868-1059 |
3.82e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 3.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 868 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRtnrssvktpEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRK 947
Cdd:PRK07764 600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA---------EASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 948 SRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTD--QPVTSEPTYQAT 1025
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|....*.
gi 1034652375 1026 RGRKNRSSVKTPEPVVPTAP--ELRPSTSTDRPVTP 1059
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPaaAPPPSPPSEEEEMA 786
|
|
| DUF4775 |
pfam16001 |
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. ... |
945-1323 |
4.53e-04 |
|
Domain of unknown function (DUF4775); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.
Pssm-ID: 406411 [Multi-domain] Cd Length: 456 Bit Score: 44.73 E-value: 4.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 945 GRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRS-SVKTPEPVVPTAPELQPSTSTDQPV-----TS 1018
Cdd:pfam16001 30 GRRTRSSTRGTPTRSAETVTPPPSKKARTSPATATKSSGGKGRGARKlDVGAEEPVEQETKKKKKVQNEPEAKeekekVS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1019 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPET-VVPTAPEL-QISTSTDQ 1096
Cdd:pfam16001 110 EPVKGKPAAKKEKKEEKKQKKKEADEKEVVEEKEKEDKEEEKTETKETDAKTAESKDQPDGVgQLPAVAEEkQNHVDEDK 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1097 PVTPKPTSR------TTRSRTNMSSVKNPEST-VPIAPELPPST------STEQPVTPEPTSRATRGRKNRSSGKTPETL 1163
Cdd:pfam16001 190 PETEEPEEKektpeeVAKAEEPPKTSENGAATdTPAAVPESESAmevdeeEKLQENTPQATADAPSDDKAVPDIKVEEKV 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1164 VPTAPKLEPSTSTDQPV---TPEPTSQATrgrTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVK 1240
Cdd:pfam16001 270 AAVSESSEEPKETSEPAkepTPEPMEVDS---SSKGSSDTAQVDTPVKEVVPAAPATESAVAAESTEASNSNNEVVEVAT 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1241 TPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPeLQPSTSTDQPVTPEPTSRATRGRTNRSS 1320
Cdd:pfam16001 347 EVKEDVPEVPPKEAESSEEPAKEAESTTAENSTPVADEVATAPASNDVSKP-VAPVAVIDTTLVETPESPVKEPQVICEV 425
|
...
gi 1034652375 1321 VKT 1323
Cdd:pfam16001 426 NKS 428
|
|
| Yop-YscD_cpl |
pfam16697 |
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ... |
57-140 |
4.54e-04 |
|
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.
Pssm-ID: 465238 [Multi-domain] Cd Length: 94 Bit Score: 41.09 E-value: 4.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 57 IFSGAH-GpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILA--WdkapILRDCGSLNGT-----------QIL 122
Cdd:pfam16697 2 VLSGPHaG--AEFPLEGGRYRIGSDPDCDIVLSDKEVSRVHLKLEVDDegW----RLDDLGSGNGTlvngqrvtelgIAL 75
|
90
....*....|....*....
gi 1034652375 123 RPPKVLSPGVSH-RLRDQE 140
Cdd:pfam16697 76 RPGDRIELGQTEfCLVPAD 94
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
896-1064 |
4.71e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 44.65 E-value: 4.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 896 KPTSQATRSRTNRSSVKTPEPVVPT--APELQPSTSTDQPVTSEPTSQVT---RGRKSRSSVKTPETVVPTALELQPSTS 970
Cdd:pfam05539 167 EPKTAVTTSKTTSWPTEVSHPTYPSqvTPQSQPATQGHQTATANQRLSSTepvGTQGTTTSSNPEPQTEPPPSQRGPSGS 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 971 TDRPVTSEPTSQATRGRKNRSsvkTPEPVVPTAPElqPSTSTDQPVTSEPTYQATRGRKnrssvKTPEPVVPTAPELRPS 1050
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEH---TQRRKTPPATS--NRRSPHSTATPPPTTKRQETGR-----PTPRPTATTQSGSSPP 316
|
170
....*....|....
gi 1034652375 1051 TSTDRPVTPKPTSR 1064
Cdd:pfam05539 317 HSSPPGVQANPTTQ 330
|
|
| FHA_EspA-like |
cd22698 |
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA ... |
63-121 |
5.13e-04 |
|
forkhead associated (FHA) domain found in Myxococcus xanthus EspA and similar proteins; EspA is a histidine protein kinase with a fork head-associated (FHA) domain at the N-terminus and a receiver domain at the C-terminus. It functions as an inhibitor of sporulation during early fruiting body development while cells are aggregating into raised mounds. EspA is part of a two-component signal transduction system that regulates the timing of sporulation initiation. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438750 [Multi-domain] Cd Length: 93 Bit Score: 40.86 E-value: 5.13e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034652375 63 GPEKDFPLHL--GKNVVGRMPDCSVALPFPSISKQHAEIEiLAWDKApILRDCGSLNGTQI 121
Cdd:cd22698 9 GSEEGKDYELdqDEFTIGRSSNNDIRLNDHSVSRHHARIV-RQGDKC-NLTDLGSTNGTFL 67
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1089-1228 |
7.45e-04 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.94 E-value: 7.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1089 QISTSTDQPVTPKPTSrttrSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP 1168
Cdd:PRK12799 292 QIDTHGTVPVAAVTPS----SAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALP 367
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1169 KLEPSTSTDQPVTPEPTSQATRGRTNRSSvKTPETVVPTAPelqpststDQPVTPEPTSQ 1228
Cdd:PRK12799 368 AAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1199-1420 |
1.15e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 43.76 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1199 KTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSS---VKTPETVVPTAPELQASASTDQPVTSEPTSRTTrgrk 1275
Cdd:PLN03209 337 DGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPLSPYTAyedLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDV---- 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1276 nrSSVKTPETVVPAAPELQPSTSTDQPVTP--------EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPE 1347
Cdd:PLN03209 413 --VPSPGSASNVPEVEPAQVEAKKTRPLSPyaryedlkPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPP 490
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034652375 1348 PT-SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPvepaaSDLEPFT 1420
Cdd:PLN03209 491 PAnMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKP-----RPLSPYT 559
|
|
| FHA_Cep170 |
cd22704 |
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) ... |
77-119 |
1.15e-03 |
|
forkhead associated (FHA) domain found in the centrosomal protein of 170 kDa protein (Cep170) family; The Cep170 family includes Cep170 and Cep170B. Cep170, also called Cep170A, KARP-1-binding protein, or KARP1-binding protein, is a protein that localizes to centrosomes as well as spindle microtubules and plays a role in microtubule organization and microtubule assembly. It is required for centriole subdistal appendage assembly. Cep170 is phosphorylated during M phase and interacts with Polo-like kinase 1 (Plk1). Cep170B, also called centrosomal protein 170B, plays a role in microtubule organization. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438756 [Multi-domain] Cd Length: 102 Bit Score: 40.00 E-value: 1.15e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1034652375 77 VGRmPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGT 119
Cdd:cd22704 21 VGR-EDCDLILQSRSVDKQHAVITYDQIDNEFKIKDLGSLNGT 62
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
832-1238 |
1.17e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 832 PTVRKTRQDGSQEAPEAPlsselEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV 911
Cdd:PRK07764 418 AAAAAPAPAAAPQPAPAP-----APAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 912 KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVV----PTALELQPSTSTDR-----PVTSEPTSQ 982
Cdd:PRK07764 493 APAAPAAPAAPAGADDAATLRERWPEILAAVPKRSRKTWAILLPEATVlgvrGDTLVLGFSTGGLArrfasPGNAEVLVT 572
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 983 ATRGRKNRssVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRgrknrssvktpepvvPTAPElrpstSTDRPVTPKPT 1062
Cdd:PRK07764 573 ALAEELGG--DWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAAR---------------PAAPA-----APAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1063 SRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSrtnmssvknPESTVPIAPELPPSTSTEQPVTPE 1142
Cdd:PRK07764 631 GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAA---------PAAPPPAPAPAAPAAPAGAAPAQP 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1143 PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTD--QPVTPEPTSQATRGRTNRSSVKTPETVVPTAP--ELQPSTSTD 1218
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQGASAPSPAADdpVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPaaAPPPSPPSE 781
|
410 420
....*....|....*....|
gi 1034652375 1219 QPVTPEPTSQATRGRTDRSS 1238
Cdd:PRK07764 782 EEEMAEDDAPSMDDEDRRDA 801
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
792-1303 |
1.28e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.92 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 792 ACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELE-PFHPKPKIRTRKSSR 870
Cdd:PRK10263 335 APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQqPVQPQQPYYAPAAEQ 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 871 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTP-----------EPVVPTAPELQPStSTDQPVTSEPT 939
Cdd:PRK10263 415 PAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPqstyqteqtyqQPAAQEPLYQQPQ-PVEQQPVVEPE 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 940 SQVTRGRKSRSSVKTPETVVPT-ALELQPSTSTDRPVtSEPtsqatrgrknrssVKTPEPVVPTAPelQPSTSTDQPVTS 1018
Cdd:PRK10263 494 PVVEETKPARPPLYYFEEVEEKrAREREQLAAWYQPI-PEP-------------VKEPEPIKSSLK--APSVAAVPPVEA 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1019 EPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS-TDRPVT--------PKPTSRTTRSRTNMSS--VKTPETVV----- 1082
Cdd:PRK10263 558 AAAVSPLASGVKKATLATGAAATVAAPVFSLANSgGPRPQVkegigpqlPRPKRIRVPTRRELASygIKLPSQRAaeeka 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1083 ------PTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSS 1156
Cdd:PRK10263 638 reaqrnQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPA 717
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1157 GKTPETL--------------VPTAPKLEPS-----TSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQpstST 1217
Cdd:PRK10263 718 GANPFSLddfefspmkallddGPHEPLFTPIvepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ---QP 794
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1218 DQPVTPEPTSQATRGRT-DRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSS-VKTPETVVPAAPELQP 1295
Cdd:PRK10263 795 QQPVAPQPQYQQPQQPVaPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRpLHKPTTPLPSLDLLTP 874
|
....*...
gi 1034652375 1296 STSTDQPV 1303
Cdd:PRK10263 875 PPSEVEPV 882
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1169-1310 |
1.43e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 43.17 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1169 KLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPT 1248
Cdd:PRK12799 286 KATGLKQIDTHGTVPVAAVTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVA 365
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034652375 1249 APELQASASTDQPVTSEPTSRTTRGRKNRSSvKTPETVVPAAPelqpststDQPVTPEPTSR 1310
Cdd:PRK12799 366 LPAAEPVNMQPQPMSTTETQQSSTGNITSTA-NGPTTSLPAAP--------ASNIPVSPTSR 418
|
|
| COG3456 |
COG3456 |
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal ... |
76-147 |
1.52e-03 |
|
Predicted component of the type VI protein secretion system, contains a FHA domain [Signal transduction mechanisms, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442679 [Multi-domain] Cd Length: 402 Bit Score: 43.21 E-value: 1.52e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034652375 76 VVGRMPDCSVALPFPS--ISKQHAEIEILawDKAPILRDCgSLNGTQILRPPKVLSPGVSHRLRDQELILFADL 147
Cdd:COG3456 29 TIGRSADCDWVLPDPDrsVSRRHAEIRFR--DGAFCLTDL-STNGTFLNGSDHPLGPGRPVRLRDGDRLRIGDY 99
|
|
| PHA03255 |
PHA03255 |
BDLF3; Provisional |
1226-1387 |
1.72e-03 |
|
BDLF3; Provisional
Pssm-ID: 165513 [Multi-domain] Cd Length: 234 Bit Score: 42.20 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1226 TSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPelqpstSTDQPVTP 1305
Cdd:PHA03255 27 SGSSTASAGNVTGTTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1306 EPTSRATRGRTNRSSVKTpesivpiapELQPSTSRNQLVTPEPTSRATRCRTNrSSVKTPEPVVPTAPEPHPTTStDQPV 1385
Cdd:PHA03255 101 NVTTKVTAQNITATEAGT---------GTSTGVTSNVTTRSSSTTSATTRITN-ATTLAPTLSSKGTSNATKTTA-ELPT 169
|
..
gi 1034652375 1386 TP 1387
Cdd:PHA03255 170 VP 171
|
|
| PRK13914 |
PRK13914 |
invasion associated endopeptidase; |
1008-1208 |
1.76e-03 |
|
invasion associated endopeptidase;
Pssm-ID: 237555 [Multi-domain] Cd Length: 481 Bit Score: 42.87 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1008 PSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPelRPSTSTDRPVTPK-PTSRTTRSR----------------- 1069
Cdd:PRK13914 147 PVAPTQEVKKETTTQQAAPAAETKTEVKQTTQATTPAP--KVAETKETPVVDQnATTHAVKSGdtiwalsvkygvsvqdi 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1070 ---TNMSS--------VKTPETVVPTAPELQisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTE-- 1136
Cdd:PRK13914 225 mswNNLSSssiyvgqkLAIKQTANTATPKAE--VKTEAPAAEKQAAPVVKENTNTNTATTEKKETTTQQQTAPKAPTEaa 302
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034652375 1137 QPvTPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTA 1208
Cdd:PRK13914 303 KP-APAPSTNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNTNTNSNTNANQGSSNNNSNSSASAIIAEA 373
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
859-973 |
1.81e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 859 PKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP 938
Cdd:PRK12799 304 VTPSSAVTQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQPQPMSTTE 383
|
90 100 110
....*....|....*....|....*....|....*.
gi 1034652375 939 TSQVTRGrKSRSSVKTPETVVPTALELQ-PSTSTDR 973
Cdd:PRK12799 384 TQQSSTG-NITSTANGPTTSLPAAPASNiPVSPTSR 418
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
857-1046 |
1.96e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.93 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 857 FHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQatrsrtnrssvktPEPVVPTAPELQPSTSTDQPvtS 936
Cdd:PRK07994 359 FHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPP-------------PASAPQQAPAVPLPETTSQL--L 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 937 EPTSQVTRgRKSRSSVKTPETVVPTALELQPStSTDRPVTSEPTSQATrgrknrssvkTPEPVVPTAPELQPSTSTDQPV 1016
Cdd:PRK07994 424 AARQQLQR-AQGATKAKKSEPAAASRARPVNS-ALERLASVRPAPSAL----------EKAPAKKEAYRWKATNPVEVKK 491
|
170 180 190
....*....|....*....|....*....|
gi 1034652375 1017 TSEPTYQATrgRKNRSSVKTPEPVVPTAPE 1046
Cdd:PRK07994 492 EPVATPKAL--KKALEHEKTPELAAKLAAE 519
|
|
| motB |
PRK12799 |
flagellar motor protein MotB; Reviewed |
1138-1269 |
2.00e-03 |
|
flagellar motor protein MotB; Reviewed
Pssm-ID: 183756 [Multi-domain] Cd Length: 421 Bit Score: 42.78 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1138 PVTPEPTSRATrgrkNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTST 1217
Cdd:PRK12799 300 PVAAVTPSSAV----TQSSAITPSSAAIPSPAVIPSSVTTQSATTTQASAVALSSAGVLPSDVTLPGTVALPAAEPVNMQ 375
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1034652375 1218 DQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQASAStdqpvtsePTSR 1269
Cdd:PRK12799 376 PQPMSTTETQQSSTGNITSTA-NGPTTSLPAAPASNIPVS--------PTSR 418
|
|
| FHA_SNIP1_DDL-like |
cd22676 |
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA ... |
54-145 |
2.03e-03 |
|
forkhead associated (FHA) domain found in Smad nuclear-interacting protein 1 (SNIP1), FHA domain-containing protein DDL, and similar proteins; SNIP1 is an FHA domain-containing protein required for pre-mRNA splicing as a component of the spliceosome. It inhibits NF-kappaB signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. It is involved in microRNA (miRNA) biogenesis. SNIP1 is a regulator of the cell cycle and cyclin D1 expression and may be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. This family also includes Arabidopsis thaliana FHA domain-containing protein DDL and similar proteins. DDL, also called protein DAWDLE, is involved in the microRNA (miRNA) and short interfering RNA (siRNA) biogenesis. It may facilitate DCL1 to access or recognize primary miRNAs. DDL binds RNA non-specifically. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438728 [Multi-domain] Cd Length: 111 Bit Score: 39.59 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 54 RLHIFSGAHGPEkdfPLHLGKN---VVGRMPD-CSVALPFPSISKQHAEIEILAWDK----------APILRDCGSLNGT 119
Cdd:cd22676 2 RLYVFKGGEQLE---TIDIHRQsayLIGRDRRvADIPLDHPSCSKQHAVIQFREVEKrnegdvieniRPYIIDLGSTNGT 78
|
90 100
....*....|....*....|....*.
gi 1034652375 120 QILRPPkvLSPGVSHRLRDQELILFA 145
Cdd:cd22676 79 FLNGEK--IEPRRYYELREKDVLKFG 102
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
1208-1339 |
2.22e-03 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 43.16 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1208 APEL--QPSTSTDQPVTPEPTSQATrgrtdrssvkTPETVVPTAPELQASaSTDQPVTSEPTSRTTRGRKNRSSVKTPET 1285
Cdd:NF033875 43 AAELdtQPGTTTVQPDNPDPQSGSE----------TPKTAVSEEATVQKD-TTSQPTKVEEVASEKNGAEQSSATPNDTT 111
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1034652375 1286 VVPAAPELQPSTSTDQPVTPEPTSRATRGRtnrssvktPESIVPIAPELQPSTS 1339
Cdd:NF033875 112 NAQQPTVGAEKSAQEQPVVSPETTNEPLGQ--------PTEVAPAENEANKSTS 157
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
897-1470 |
2.45e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.83 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 897 PTSQATRS--RTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRP 974
Cdd:pfam03154 34 PTNEDLRSsgRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREKGASDTEEPERATAKKSKTQEISRPNSP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 975 VTSEPTSQATRGRKNRSSvKTPEPVVPTAPELQPSTST--DQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTS 1052
Cdd:pfam03154 114 SEGEGESSDGRSVNDEGS-SDPKDIDQDNRSTSPSIPSpqDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTT 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1053 TDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSrttrsrtnmssvknPESTVPIAPELPPS 1132
Cdd:pfam03154 193 QAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPS--------------PHPPLQPMTQPPPP 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1133 TSTEQPVTPEPTSRATRGRKNRSSGKTPETL---VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPEtvvPTAP 1209
Cdd:pfam03154 259 SQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMqhpVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQ---SQLQ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1210 ELQPstSTDQPVTPEPTSQatrgrtdrssvktpetvvptaPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPA 1289
Cdd:pfam03154 336 SQQP--PREQPLPPAPLSM---------------------PHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1290 APELQP--STSTDQPVTPEPtsratrgrtnrssvkTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEP 1367
Cdd:pfam03154 393 PPALKPlsSLSTHHPPSAHP---------------PPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVP 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1368 VVPTAPEPHPTTSTDQPVTPKLTsratrrktnrssvkTPKPVEPAASDLEPftPTDQSVTPEAIAQGGQSKTLRSSTVRA 1447
Cdd:pfam03154 458 SQSPFPQHPFVPGGPPPITPPSG--------------PPTSTSSAMPGIQP--PSSASVSSSGPVPAAVSCPLPPVQIKE 521
|
570 580
....*....|....*....|...
gi 1034652375 1448 MPVPTTPEFQSPVTTDQPISPEP 1470
Cdd:pfam03154 522 EALDEAEEPESPPPPPRSPSPEP 544
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1049-1298 |
2.62e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.61 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1049 PSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTS-RTTRSRTNMSSVKNPESTVPIap 1127
Cdd:PLN03209 312 PLTPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVpRPLSPYTAYEDLKPPTSPIPT-- 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1128 elPPSTSTEQPVTPEPTSRATRGRKNRSSGKT---PETLVPTAPK-----LEPSTSTDQ---PVTPEPTSQATRGRTNRS 1196
Cdd:PLN03209 390 --PPSSSPASSKSVDAVAKPAEPDVVPSPGSAsnvPEVEPAQVEAkktrpLSPYARYEDlkpPTSPSPTAPTGVSPSVSS 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1197 S---VKTPETVVPTA--PELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTT 1271
Cdd:PLN03209 468 TssvPAVPDTAPATAatDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHH 547
|
250 260
....*....|....*....|....*..
gi 1034652375 1272 RGRKNRssvktPETVVPAAPELQPSTS 1298
Cdd:PLN03209 548 AQPKPR-----PLSPYTMYEDLKPPTS 569
|
|
| FHA_ZEP-like |
cd22702 |
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar ... |
69-144 |
3.02e-03 |
|
forkhead associated (FHA) domain found in chloroplastic zeaxanthin epoxidase (ZEP) and similar proteins; ZEP, also called protein ABA DEFICIENT 1, ABA1, protein IMPAIRED IN BABA-INDUCED STERILITY 3, protein LOW EXPRESSION OF OSMOTIC STRESS-RESPONSIVE GENES 6, or protein NON-PHOTOCHEMICAL QUENCHING 2, plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. It converts zeaxanthin into antheraxanthin and subsequently violaxanthin. ZEP is required for resistance to osmotic and drought stresses, ABA-dependent stomatal closure, seed development and dormancy, modulation of defense gene expression, and disease resistance and non-photochemical quencing (NPQ). The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438754 [Multi-domain] Cd Length: 123 Bit Score: 39.33 E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 69 PLHLGKN-----VVGRMPDC-----SVALPFPSISKQHAEIEILawDKAPILRDCGSLNGTQILRPP---KVLSPGVSHR 135
Cdd:cd22702 23 PIRLTRDekqpcIIGSDPHQaisgiSVVIPSPQVSELHARITCK--NGAFFLTDLGSEHGTWINDNEgrrYRAPPNFPVR 100
|
....*....
gi 1034652375 136 LRDQELILF 144
Cdd:cd22702 101 LHPSDVIEF 109
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1072-1339 |
3.97e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.84 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1072 MSSVKTPETVVPTAPELqisTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPvtpePTSRATRGR 1151
Cdd:PLN03209 297 LSYCKVVEVIAETTAPL---TPMEELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEEP----PQPKAVVPR 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1152 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTP-------- 1223
Cdd:PLN03209 370 PLSPYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEP-AQVEAKKTRPLSPyaryedlk 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1224 EPTSQATRGRTDRSSVKTPETVVPTAPELQ-ASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1302
Cdd:PLN03209 449 PPTSPSPTAPTGVSPSVSSTSSVPAVPDTApATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNE 528
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1034652375 1303 VTP----EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTS 1339
Cdd:PLN03209 529 VVKvgnsAPPTALADEQHHAQPKPRPLSPYTMYEDLKPPTS 569
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
876-1105 |
4.50e-03 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 41.66 E-value: 4.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 876 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTP 955
Cdd:COG3469 1 SSSVSTAASPTAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 956 ETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNrSSVK 1035
Cdd:COG3469 81 TATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSG-TETA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1036 TPEPVVPTAPELRPSTSTDRPVTPKPTsrttrsrtnmssvkTPETVVPTAPELQISTSTDQPVTPKPTSR 1105
Cdd:COG3469 160 TGGTTTTSTTTTTTSASTTPSATTTAT--------------ATTASGATTPSATTTATTTGPPTPGLPKH 215
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
878-1146 |
5.04e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 41.59 E-value: 5.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 878 SAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAP-ELQPSTSTDQPVTSEPTSQVTRGRK--SRSSVKT 954
Cdd:pfam04747 187 SAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPaSVEQVVEQPKVVTEEPHQQAAPQEKknKKNKRKS 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 955 PETVVPTALE--LQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQpvTSEPTYQATRGRKNRS 1032
Cdd:pfam04747 267 ESENVPAASEtpVEPVVETTPPASENQKKNKKDKKKSESEKVVEEPVQAEAPKSKKPTADDN--MDFLDFVTAKEEPKDE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1033 SVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETvvptapelqistsTDQPV--TPKPTSRTTRSR 1110
Cdd:pfam04747 345 PAETPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESEKV-------------TEQPVesAPAPPQVEQVVE 411
|
250 260 270
....*....|....*....|....*....|....*.
gi 1034652375 1111 TNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSR 1146
Cdd:pfam04747 412 TTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSK 447
|
|
| FHA_RAD53-like_rpt2 |
cd22690 |
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine ... |
53-148 |
5.25e-03 |
|
second forkhead associated (FHA) domain found in Saccharomyces cerevisiae Serine/threonine-protein kinase RAD53 and similar proteins; RAD53, also called CHEK2 homolog, or serine-protein kinase 1 (Spk1), is a nuclear protein kinase that phosphorylates proteins on serine, threonine, and tyrosine. It controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints and prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5. It may be involved in the phosphorylation of RPH1. RAD53 contains two FHA domains. This model corresponds to the second one. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438742 [Multi-domain] Cd Length: 105 Bit Score: 38.43 E-value: 5.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 53 GRLHIFSGAHgpeKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPI---LRDCgSLNGTQILRppKVLS 129
Cdd:cd22690 2 GRLKSLNPSY---PDIELTQNTTFIGRSKDCDEEITDPRISKHHCIITRKRSGKGLDdvyVTDT-STNGTFINN--NRLG 75
|
90 100
....*....|....*....|
gi 1034652375 130 PGVSHRLRD-QELILFADLL 148
Cdd:cd22690 76 KGSQSLLQDgDEIVLIWDKN 95
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
1190-1474 |
5.91e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 41.52 E-value: 5.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1190 RGRTNRSSVKTPETVVPTAPeLQPSTSTDQPVTPEPTSQAT---RGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1266
Cdd:PHA03369 340 GLKAHNEILKTASLTAPSRV-LAAAAKVAVIAAPQTHTGPAdrqRPQRPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSP 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1267 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT-RGRTNRSSVKtpESIVPIAPELQPSTSRNQLVT 1345
Cdd:PHA03369 419 YNPQSPGTSYGPEPVGPVPPQPTNPYVMPISMANMVYPGHPQEHGHeRKRKRGGELK--EELIETLKLVKKLKEEQESLA 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1346 PEPTSRATRCRTNRSS--------VKTPEPVV---PTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAAS 1414
Cdd:PHA03369 497 KELEATAHKSEIKKIAesefknagAKTAAANIepnCSADAAAPATKRARPETKTELEAVVRFPYQIRNMESPAFVHSFTS 576
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034652375 1415 DLEPFTPTDQSVTPEAIAqgGQSKTLrSSTVRAMPVPTTPEFQ-------SPVTTDQPISPEPITQP 1474
Cdd:PHA03369 577 TTLAAAAGQGSDTAEALA--GAIETL-LTQASAQPAGLSLPAPavpvnasTPASTPPPLAPQEPPQP 640
|
|
| FHA_Rv1747-like_rpt2 |
cd22737 |
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
77-119 |
7.04e-03 |
|
second forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the second FHA domain, which has a circularly permuted FHA domain fold with a conserved pThr-binding interface.
Pssm-ID: 439356 [Multi-domain] Cd Length: 93 Bit Score: 37.47 E-value: 7.04e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1034652375 77 VGRMPDCSVALPFPSISKQHAEIEILawDKAPILRDCGSLNGT 119
Cdd:cd22737 25 IGRASDNDIVIPEGSVSRHHATLVPT--PGGTQIRDLRSTNGT 65
|
|
| DUF612 |
pfam04747 |
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ... |
1128-1418 |
7.27e-03 |
|
Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.
Pssm-ID: 282585 [Multi-domain] Cd Length: 511 Bit Score: 41.20 E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1128 ELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLV--------PTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVK 1199
Cdd:pfam04747 142 KLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVvkkvandrSAAPAPEPKTPTNTPAEPAEQVQEITGKKNKKNKK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1200 TPETVVPTAP-ELQPSTSTDQPVTPEPTSQAT--RGRTDRSSVKTPETVVPTAPELQASASTD-QPVTSEPTSRTTRGRK 1275
Cdd:pfam04747 222 KSESEATAAPaSVEQVVEQPKVVTEEPHQQAApqEKKNKKNKRKSESENVPAASETPVEPVVEtTPPASENQKKNKKDKK 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1276 NRSSVKTPETVVPA-APELQPSTSTDQPVTPEPTSraTRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATR 1354
Cdd:pfam04747 302 KSESEKVVEEPVQAeAPKSKKPTADDNMDFLDFVT--AKEEPKDEPAETPAAPVEEVVENVVENVVEKSTTPPATENKKK 379
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1355 CRTNR----SSVKTPEPV--VPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEP 1418
Cdd:pfam04747 380 NKKDKkkseSEKVTEQPVesAPAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSKKP 449
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1294-1636 |
7.40e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 7.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1294 QPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPvvptAP 1373
Cdd:PHA03307 40 QGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSS----PD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1374 EPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAiaqggqsktlrsSTVRAMPVPTT 1453
Cdd:PHA03307 116 PPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQA------------ALPLSSPEETA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1454 PEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPK-SQASRNQRWGAVRAAESLTAIPEPaSP 1532
Cdd:PHA03307 184 RAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASsSDSSSSESSGCGWGPENECPLPRP-AP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1533 QLLETPIHASQIQKVE-----PAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQ--PQRGEVSQKTVIIKEEEEDTAEK 1605
Cdd:PHA03307 263 ITLPTRIWEASGWNGPssrpgPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSssSSRESSSSSTSSSSESSRGAAVS 342
|
330 340 350
....*....|....*....|....*....|.
gi 1034652375 1606 PGKEEDvvtpKPGKRKRDQAEEEPNRIPSRS 1636
Cdd:PHA03307 343 PGPSPS----RSPSPSRPPPPADPSSPRKRP 369
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1184-1423 |
7.70e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.37 E-value: 7.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1184 PTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVT 1263
Cdd:PRK07003 381 PAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASAD 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1264 SEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPvtPEPTSRATRGRTNRSSVKTPESIVPIAPElQPSTSRNQL 1343
Cdd:PRK07003 461 SRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAP--SAATPAAVPDARAPAAASREDAPAAAAPP-APEARPPTP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1344 VTPEPTSRAT--------------RCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTpKPV 1409
Cdd:PRK07003 538 AAAAPAARAGgaaaaldvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGA-ARA 616
|
250
....*....|....
gi 1034652375 1410 EPAASDLEPFTPTD 1423
Cdd:PRK07003 617 EQAAESRGAPPPWE 630
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
706-1106 |
8.14e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 8.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 706 EDNYGDSedlDLQATQCFLENQGLEVQSME----------DEPTQAFMLTPPqelgPSHCSFQTTGLLNCKMPPAEKASR 775
Cdd:pfam03154 152 QDNESDS---DSSAQQQILQTQPPVLQAQSgaasppspppPGTTQAATAGPT----PSAPSVPPQGSPATSQPPNQTQST 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 776 IRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLlpsikPTVRKTRQDGSQEAPEAPlssele 855
Cdd:pfam03154 225 AAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQM-----PPMPHSLQTGPSHMQHPV------ 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 856 PFHPKPKIRTRKSSRMTPFPATSAapePHPSTSTAQpvTPKPTSQATRSRTNRSSVKTPEPVvpTAPELQPSTSTDQPVT 935
Cdd:pfam03154 294 PPQPFPLTPQSSQSQVPPGPSPAA---PGQSQQRIH--TPPSQSQLQSQQPPREQPLPPAPL--SMPHIKPPPTTPIPQL 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 936 SEPTSQVTRGRKSRSSVKTPETVVPTALELQP--STSTDRPVTSEP-------TSQATRGRKNRSSVKTPEPVVPTAPEL 1006
Cdd:pfam03154 367 PNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPlsSLSTHHPPSAHPpplqlmpQSQQLPPPPAQPPVLTQSQSLPPPAAS 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1007 QPSTSTDQPVTSEPTYqatrgrknrssvkTPEPVVPTAPELRPSTSTDRPVTPK--PTSRTTRSRTNMSSVKTPETVVPT 1084
Cdd:pfam03154 447 HPPTSGLHQVPSQSPF-------------PQHPFVPGGPPPITPPSGPPTSTSSamPGIQPPSSASVSSSGPVPAAVSCP 513
|
410 420
....*....|....*....|....*.
gi 1034652375 1085 APELQIST----STDQPVTPKPTSRT 1106
Cdd:pfam03154 514 LPPVQIKEealdEAEEPESPPPPPRS 539
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
795-995 |
9.50e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 9.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 795 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPkiRTRKSSRMTPF 874
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQAS--ARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 875 PATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEP-VVPTAPELQPSTSTDQPVTSEPT-SQVTRGRKSRSSV 952
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADdDPPPWEELPPEFASPAPAQPDAApAGWVAESIPDPAT 531
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1034652375 953 KTPETVVPTALELQPSTSTDRP-VTSEPTSQATRGRKNRSSVKT 995
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPRAaAATEPVVAPRPPRASASGLPD 575
|
|
| FHA_Rv1747-like_rpt1 |
cd22694 |
first forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ... |
76-119 |
9.51e-03 |
|
first forkhead associated (FHA) domain found in Mycobacterium tuberculosis ABC transporter ATP-binding/permease protein Rv1747 and similar proteins; Rv1747 is a putative ATP-binding cassette (ABC) transporter involved in the translocation of an unknown substrate across the membrane. It is required for normal virulent infection by M. tuberculosis. Rv1747 has a cytoplasmic regulatory module consisting of two pThr-interacting forkhead-associated (FHA) domains connected by a conformationally disordered linker with two phospho-acceptor threonines (pThr). Recruitment and phosphorylation of Rv1747 depend on the interaction between its two non-redundant FHA domains and the autophosphorylated form of serine/threonine protein kinase PknF. This model corresponds to the first FHA domain. The FHA domain is a small phosphopeptide recognition module.
Pssm-ID: 438746 [Multi-domain] Cd Length: 93 Bit Score: 37.31 E-value: 9.51e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1034652375 76 VVGRMPDCSVALPFPSISKQHAEIEIL--AWdkapILRDCGSLNGT 119
Cdd:cd22694 19 RIGRDPDADVRLDDPRVSRRHALLEFDgdGW----VYTDLGSRNGT 60
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
1125-1367 |
9.71e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 40.68 E-value: 9.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1125 IAPELPPSTSTEQPVTPEPTSRATRgrKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRG---RTNRSSVKTP 1201
Cdd:PLN03209 306 IAETTAPLTPMEELLAKIPSQRVPP--KESDAADGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspYTAYEDLKPP 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1202 ETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSvKTPETVVPTAPELQA---SASTDQPVTSEPTSRTTRGRKNRS 1278
Cdd:PLN03209 384 TSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSAS-NVPEVEPAQVEAKKTrplSPYARYEDLKPPTSPSPTAPTGVS 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034652375 1279 SVKTPETVVPAAPELQPSTS-TDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRT 1357
Cdd:PLN03209 463 PSVSSTSSVPAVPDTAPATAaTDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALA 542
|
250
....*....|
gi 1034652375 1358 NRSSVKTPEP 1367
Cdd:PLN03209 543 DEQHHAQPKP 552
|
|
| |
