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Conserved domains on  [gi|1034644878|ref|XP_016864934|]
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uncharacterized protein C5orf34 isoform X2 [Homo sapiens]

Protein Classification

DUF4520 domain-containing protein( domain architecture ID 10386725)

DUF4520 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4520 pfam15016
Domain of unknown function (DUF4520); This family of proteins is found in eukaryotes. Proteins ...
 333-424 6.15e-42

Domain of unknown function (DUF4520); This family of proteins is found in eukaryotes. Proteins in this family are typically between 197 and 638 amino acids in length.This is the C-terminal domain of the member proteins.


:

Pssm-ID: 434393  Cd Length: 89  Bit Score: 144.79  E-value: 6.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034644878 333 ILPLVLKESLIPSVGRFLAYSDDKVHAIFLDGITLTLNWNFSSpiEKRQVNqGLNLGWCKLTFPDGQEQLIQIEHPEPYE 412
Cdd:pfam15016   1 MSPVVLEESTIPGIGRFTAYSDGRVHVHFDDRTILTLVWDFSS--GKTQVN-RESTGWCKLLLPDGQQVLVRIEHPGHYE 77

                          90
                  ....*....|..
gi 1034644878 413 RYVTTVTSWCRR 424
Cdd:pfam15016  78 RYVAAALEFCRW 89
DUF4524 super family cl20901
Domain of unknown function (DUF4524); This family of proteins is found in eukaryotes. Proteins ...
 1-38 2.78e-13

Domain of unknown function (DUF4524); This family of proteins is found in eukaryotes. Proteins in this family are typically between 197 and 638 amino acids in length.This is the N-terminal domain of the member proteins. The human gene is from C5orf34.


The actual alignment was detected with superfamily member pfam15025:

Pssm-ID: 464454  Cd Length: 146  Bit Score: 67.34  E-value: 2.78e-13
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1034644878   1 MIYMESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVS 38
Cdd:pfam15025 109 VTRGDGGSVTVSSEDGAAQLVLSPHQEEFTVEFLCKVS 146
 
Name Accession Description Interval E-value
DUF4520 pfam15016
Domain of unknown function (DUF4520); This family of proteins is found in eukaryotes. Proteins ...
 333-424 6.15e-42

Domain of unknown function (DUF4520); This family of proteins is found in eukaryotes. Proteins in this family are typically between 197 and 638 amino acids in length.This is the C-terminal domain of the member proteins.


Pssm-ID: 434393  Cd Length: 89  Bit Score: 144.79  E-value: 6.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034644878 333 ILPLVLKESLIPSVGRFLAYSDDKVHAIFLDGITLTLNWNFSSpiEKRQVNqGLNLGWCKLTFPDGQEQLIQIEHPEPYE 412
Cdd:pfam15016   1 MSPVVLEESTIPGIGRFTAYSDGRVHVHFDDRTILTLVWDFSS--GKTQVN-RESTGWCKLLLPDGQQVLVRIEHPGHYE 77

                          90
                  ....*....|..
gi 1034644878 413 RYVTTVTSWCRR 424
Cdd:pfam15016  78 RYVAAALEFCRW 89
DUF4524 pfam15025
Domain of unknown function (DUF4524); This family of proteins is found in eukaryotes. Proteins ...
 1-38 2.78e-13

Domain of unknown function (DUF4524); This family of proteins is found in eukaryotes. Proteins in this family are typically between 197 and 638 amino acids in length.This is the N-terminal domain of the member proteins. The human gene is from C5orf34.


Pssm-ID: 464454  Cd Length: 146  Bit Score: 67.34  E-value: 2.78e-13
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1034644878   1 MIYMESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVS 38
Cdd:pfam15025 109 VTRGDGGSVTVSSEDGAAQLVLSPHQEEFTVEFLCKVS 146
 
Name Accession Description Interval E-value
DUF4520 pfam15016
Domain of unknown function (DUF4520); This family of proteins is found in eukaryotes. Proteins ...
 333-424 6.15e-42

Domain of unknown function (DUF4520); This family of proteins is found in eukaryotes. Proteins in this family are typically between 197 and 638 amino acids in length.This is the C-terminal domain of the member proteins.


Pssm-ID: 434393  Cd Length: 89  Bit Score: 144.79  E-value: 6.15e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034644878 333 ILPLVLKESLIPSVGRFLAYSDDKVHAIFLDGITLTLNWNFSSpiEKRQVNqGLNLGWCKLTFPDGQEQLIQIEHPEPYE 412
Cdd:pfam15016   1 MSPVVLEESTIPGIGRFTAYSDGRVHVHFDDRTILTLVWDFSS--GKTQVN-RESTGWCKLLLPDGQQVLVRIEHPGHYE 77

                          90
                  ....*....|..
gi 1034644878 413 RYVTTVTSWCRR 424
Cdd:pfam15016  78 RYVAAALEFCRW 89
DUF4524 pfam15025
Domain of unknown function (DUF4524); This family of proteins is found in eukaryotes. Proteins ...
 1-38 2.78e-13

Domain of unknown function (DUF4524); This family of proteins is found in eukaryotes. Proteins in this family are typically between 197 and 638 amino acids in length.This is the N-terminal domain of the member proteins. The human gene is from C5orf34.


Pssm-ID: 464454  Cd Length: 146  Bit Score: 67.34  E-value: 2.78e-13
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1034644878   1 MIYMESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVS 38
Cdd:pfam15025 109 VTRGDGGSVTVSSEDGAAQLVLSPHQEEFTVEFLCKVS 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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