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Concise Results
Standard Results
Full Results
cation:proton antiporter [Lactiplantibacillus plantarum]
Protein Classification
cation:proton antiporter ( domain architecture ID 10001451 )
cation:proton antiporter functions in maintaining cation homeostasis and the pH of actively metabolizing cells; it may also be involved in regulating cell volume
List of domain hits
Name
Accession
Description
Interval
E-value
KefB
COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
1-386
3.99e-83
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
:Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 258.54
E-value: 3.99e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 1 MDYVGS L A L I L IVTAV AG H L SV R M GLP A V I G QL L S GI I LGP AV LG WVSATSFIKDF AELGV II L M F MA GLE S DLK L L K K Y 80
Cdd:COG0475 3 ASLLLQ L G L L L LAAVL AG L L AR R L GLP S V L G YI L A GI L LGP SG LG LIEDSEALELL AELGV VL L L F LI GLE L DLK R L R K M 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 81 W R PS L LVAV L G V V LP VAVIDWCSQ L FH L NATES LFLG VTF AATS VS I SVA VLKELG A L DGKE G TT ILG A A VV DD VL A V L I 160
Cdd:COG0475 83 G R RA L GIGL L Q V L LP FLLGFLLAL L LG L SLAAA LFLG AAL AATS TA I VLK VLKELG L L KTPL G QL ILG V A LF DD IA A I L L 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 L S L MIS L fgsevs G GG SHASTN L G L S L AIQ L A F FVA L YF V VKWVVPH L MAVGNALLVPTSIT L MS L VICFGLSY LA DAI G 240
Cdd:COG0475 163 L A L VPA L ------ A GG GSVAGS L L L A L LKA L L F LAL L LL V GRYLLRR L FRLVARTRSRELFL L FA L LLVLLAAA LA ELL G 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSA VI GAF F AG IAVGQTD Y HEVID E H I Q P I G N a V F I P V FFVS I GL NMSFNGF L NDFWFIAVITV AAI AT K II GA GVG ARL 320
Cdd:COG0475 237 LSA AL GAF L AG LVLAESE Y RHELE E K I E P F G D - L F L P L FFVS V GL SLDLSAL L SNPLLALLLVL AAI VG K LL GA YLA ARL 315
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 321 A G FNWLSGYE IG AGMVS RGE M AL II A QI G YQGK L L S ADRYS A VITAII LTTL IA PLLLR Q A VKRQR 386
Cdd:COG0475 316 F G LSRREALR IG LLLAP RGE F AL VL A SL G LSAG L I S PELFA A LVLVVL LTTL LT PLLLR L A LRLAE 381
Name
Accession
Description
Interval
E-value
KefB
COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
1-386
3.99e-83
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 258.54
E-value: 3.99e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 1 MDYVGS L A L I L IVTAV AG H L SV R M GLP A V I G QL L S GI I LGP AV LG WVSATSFIKDF AELGV II L M F MA GLE S DLK L L K K Y 80
Cdd:COG0475 3 ASLLLQ L G L L L LAAVL AG L L AR R L GLP S V L G YI L A GI L LGP SG LG LIEDSEALELL AELGV VL L L F LI GLE L DLK R L R K M 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 81 W R PS L LVAV L G V V LP VAVIDWCSQ L FH L NATES LFLG VTF AATS VS I SVA VLKELG A L DGKE G TT ILG A A VV DD VL A V L I 160
Cdd:COG0475 83 G R RA L GIGL L Q V L LP FLLGFLLAL L LG L SLAAA LFLG AAL AATS TA I VLK VLKELG L L KTPL G QL ILG V A LF DD IA A I L L 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 L S L MIS L fgsevs G GG SHASTN L G L S L AIQ L A F FVA L YF V VKWVVPH L MAVGNALLVPTSIT L MS L VICFGLSY LA DAI G 240
Cdd:COG0475 163 L A L VPA L ------ A GG GSVAGS L L L A L LKA L L F LAL L LL V GRYLLRR L FRLVARTRSRELFL L FA L LLVLLAAA LA ELL G 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSA VI GAF F AG IAVGQTD Y HEVID E H I Q P I G N a V F I P V FFVS I GL NMSFNGF L NDFWFIAVITV AAI AT K II GA GVG ARL 320
Cdd:COG0475 237 LSA AL GAF L AG LVLAESE Y RHELE E K I E P F G D - L F L P L FFVS V GL SLDLSAL L SNPLLALLLVL AAI VG K LL GA YLA ARL 315
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 321 A G FNWLSGYE IG AGMVS RGE M AL II A QI G YQGK L L S ADRYS A VITAII LTTL IA PLLLR Q A VKRQR 386
Cdd:COG0475 316 F G LSRREALR IG LLLAP RGE F AL VL A SL G LSAG L I S PELFA A LVLVVL LTTL LT PLLLR L A LRLAE 381
2a37
TIGR00932
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
11-288
1.70e-55
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273348 [Multi-domain]
Cd Length: 273
Bit Score: 183.62
E-value: 1.70e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 11 L IVTAV A GH LS V R M G L P A V I G Q LL S G IIL GP AV LG WV S ATSFIKDF AE L GVI I LMF MA GLE S DL KL L K K YWRPSLL V A VL 90
Cdd:TIGR00932 1 L LAAVL A VP LS R R L G I P S V L G Y LL A G VLI GP SG LG LI S NVEGVNHL AE F GVI L LMF LI GLE L DL ER L W K LRKAAFG V G VL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 91 G V VL P VAVIDWC - SQ L FH L NATESLFL G VTF A AT S VSIS V A VLKE L G A L DGKE G T T I LG AAVVD D VLA V LI L S L MIS L fg 169
Cdd:TIGR00932 81 Q V LV P GVLLGLL l GH L LG L ALGAAVVI G IIL A LS S TAVV V Q VLKE R G L L KTPF G Q T V LG ILLFQ D IAV V PL L A L LPL L -- 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 170 sev SGGG S HASTN L G L S L AIQLAF F VA L YFVVK W VVPHLMAVGNA L LVPTSI T LM SL VIC FG LS Y L AD AI GLS AVI GAF F 249
Cdd:TIGR00932 159 --- ATSA S TEHVA L A L L L LKVFLA F LL L VLLGR W LLRPVLRLTAE L RPSELF T AG SL LLM FG SA Y F AD LL GLS MAL GAF L 235
250 260 270
....*....|....*....|....*....|....*....
gi 1027832817 250 AG IAVGQTD Y HEVIDEHIQ PIG n A V FI P V FF V S I G LNMS 288
Cdd:TIGR00932 236 AG VVLSESE Y RHKLESDLE PIG - G V LL P L FF I S V G MSVD 273
Na_H_Exchanger
pfam00999
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
7-384
1.37e-45
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain]
Cd Length: 377
Bit Score: 160.88
E-value: 1.37e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 7 LA L ILIVTAV A GH L SV R MG LP AVI G QLLS GI I LGP AV LG WV S - ATSFIKDFAE LG VII L M F M AGLE S DL KL L K K YWRPS L 85
Cdd:pfam00999 1 IV L LILLALL A PL L AR R LK LP PIV G LIIA GI L LGP SG LG LI S e VDEDLEVLSN LG LPP L L F L AGLE L DL RE L R K NGGSI L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 86 L V A V LGV VL P VAV I DWC -- SQLFHLNAT E S L FL G VTFA ATS VSISV A V LKELG ALDGKE GT TI LG AA V VD D VL AV LI L SL 163
Cdd:pfam00999 81 L L A L LGV LI P FVL I GLL ly LLGLGIPLL E A L LF G AILS ATS PVVVL A I LKELG RVPERL GT LL LG ES V LN D GV AV VL L AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 164 MIS L FGSEVS G GGS hastnlg LS L AIQLAFFVALYFVVKWVVPH L MAVGNALLVPTSITLM -- S L VICFGLSY LA D A I G L 241
Cdd:pfam00999 161 LLA L AQGVGG G SDL ------- GW L LLIFLVVAVGGLLLGLLIGW L LRLITRFTDDDRELEV ll V L LLALLAAL LA E A L G V 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 242 S AVI GAF F AG IAVGQTDYHEVID E HIQ P I G NAV F I P V FFV SI GL NMSFNGF L NDF W FIAVITVA AI - ATKII G AGVGA RL 320
Cdd:pfam00999 234 S GIL GAF L AG LVLSEYPFANKLS E KLE P F G YGL F N P L FFV LV GL SLDLSSL L LSV W ILVLLALV AI l LGRFL G VFLLL RL 313
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1027832817 321 A G FNWLSGYE IG A G MVS RG EMA L II A Q IG YQGKLLSADR Y SAV I TAIIL T T L IAPLL L RQAVKR 384
Cdd:pfam00999 314 L G LSLREALI IG F G GLQ RG AVS L AL A A IG PLLGIIAREL Y PLL I VVVLF T V L VQGIT L KPLLFK 377
PRK03562
PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
8-378
2.07e-27
glutathione-regulated potassium-efflux system protein KefC; Provisional
Pssm-ID: 235131 [Multi-domain]
Cd Length: 621
Bit Score: 113.94
E-value: 2.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 8 ALI LIVT AV - AGHLS VR M GL PA V I G Q L LS G I I L GP AV L GW V SATSF I KD FAE L GV IILM F MA GLE S D LKL L K K YW R PSLL 86
Cdd:PRK03562 10 ALI YLGA AV l IVPIA VR L GL GS V L G Y L IA G C I I GP WG L RL V TDVES I LH FAE F GV VLML F VI GLE L D PQR L W K LR R SIFG 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 87 VAV L GV V LPVAVIDWCSQ L FH L NATES L FL G VTF A AT S VS I SVAVLK E LGALDGKE G TTILGAAVVD D VL A VLILS l MI S 166
Cdd:PRK03562 90 GGA L QM V ACGGLLGLFCM L LG L RWQVA L LI G LGL A LS S TA I AMQAMN E RNLMVTQM G RSAFAILLFQ D IA A IPLVA - MI P 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 167 L FGSE vsg G G S HASTNLG LS LAIQLAFFVALYFVVKW V V - P H L MA V GNAL L v PTSI T LMS L VIC FG LSY L ADAI GLS AVI 245
Cdd:PRK03562 169 L LAAS --- G A S TTLGAFA LS ALKVAGALALVVLGGRY V T r P A L RF V ARSG L - REVF T AVA L FLV FG FGL L MEEV GLS MAL 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 246 GAF F AG IAVGQTD Y HEVIDEH I Q P I g NAVFIPV FF VSI G LNMS F NGF L NDFWF I AVITVAAI A T KI IGAGVG AR LA G F -- 323
Cdd:PRK03562 245 GAF L AG VLLASSE Y RHALESD I E P F - KGLLLGL FF IAV G MSID F GTL L ENPLR I LILLLGFL A I KI AMLWLL AR PL G V pr 323
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 324 -- NWLSGYEI G A G mvsr GE M A LIIAQIGYQGKL L SADRYSAVIT A II L TTLIA PLLL 378
Cdd:PRK03562 324 kq RRWFAVLL G Q G ---- GE F A FVVFGAAQMANV L EPEWAKLLTL A VA L SMAAT PLLL 376
Name
Accession
Description
Interval
E-value
KefB
COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
1-386
3.99e-83
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 258.54
E-value: 3.99e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 1 MDYVGS L A L I L IVTAV AG H L SV R M GLP A V I G QL L S GI I LGP AV LG WVSATSFIKDF AELGV II L M F MA GLE S DLK L L K K Y 80
Cdd:COG0475 3 ASLLLQ L G L L L LAAVL AG L L AR R L GLP S V L G YI L A GI L LGP SG LG LIEDSEALELL AELGV VL L L F LI GLE L DLK R L R K M 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 81 W R PS L LVAV L G V V LP VAVIDWCSQ L FH L NATES LFLG VTF AATS VS I SVA VLKELG A L DGKE G TT ILG A A VV DD VL A V L I 160
Cdd:COG0475 83 G R RA L GIGL L Q V L LP FLLGFLLAL L LG L SLAAA LFLG AAL AATS TA I VLK VLKELG L L KTPL G QL ILG V A LF DD IA A I L L 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 L S L MIS L fgsevs G GG SHASTN L G L S L AIQ L A F FVA L YF V VKWVVPH L MAVGNALLVPTSIT L MS L VICFGLSY LA DAI G 240
Cdd:COG0475 163 L A L VPA L ------ A GG GSVAGS L L L A L LKA L L F LAL L LL V GRYLLRR L FRLVARTRSRELFL L FA L LLVLLAAA LA ELL G 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSA VI GAF F AG IAVGQTD Y HEVID E H I Q P I G N a V F I P V FFVS I GL NMSFNGF L NDFWFIAVITV AAI AT K II GA GVG ARL 320
Cdd:COG0475 237 LSA AL GAF L AG LVLAESE Y RHELE E K I E P F G D - L F L P L FFVS V GL SLDLSAL L SNPLLALLLVL AAI VG K LL GA YLA ARL 315
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 321 A G FNWLSGYE IG AGMVS RGE M AL II A QI G YQGK L L S ADRYS A VITAII LTTL IA PLLLR Q A VKRQR 386
Cdd:COG0475 316 F G LSRREALR IG LLLAP RGE F AL VL A SL G LSAG L I S PELFA A LVLVVL LTTL LT PLLLR L A LRLAE 381
2a37
TIGR00932
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
11-288
1.70e-55
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273348 [Multi-domain]
Cd Length: 273
Bit Score: 183.62
E-value: 1.70e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 11 L IVTAV A GH LS V R M G L P A V I G Q LL S G IIL GP AV LG WV S ATSFIKDF AE L GVI I LMF MA GLE S DL KL L K K YWRPSLL V A VL 90
Cdd:TIGR00932 1 L LAAVL A VP LS R R L G I P S V L G Y LL A G VLI GP SG LG LI S NVEGVNHL AE F GVI L LMF LI GLE L DL ER L W K LRKAAFG V G VL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 91 G V VL P VAVIDWC - SQ L FH L NATESLFL G VTF A AT S VSIS V A VLKE L G A L DGKE G T T I LG AAVVD D VLA V LI L S L MIS L fg 169
Cdd:TIGR00932 81 Q V LV P GVLLGLL l GH L LG L ALGAAVVI G IIL A LS S TAVV V Q VLKE R G L L KTPF G Q T V LG ILLFQ D IAV V PL L A L LPL L -- 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 170 sev SGGG S HASTN L G L S L AIQLAF F VA L YFVVK W VVPHLMAVGNA L LVPTSI T LM SL VIC FG LS Y L AD AI GLS AVI GAF F 249
Cdd:TIGR00932 159 --- ATSA S TEHVA L A L L L LKVFLA F LL L VLLGR W LLRPVLRLTAE L RPSELF T AG SL LLM FG SA Y F AD LL GLS MAL GAF L 235
250 260 270
....*....|....*....|....*....|....*....
gi 1027832817 250 AG IAVGQTD Y HEVIDEHIQ PIG n A V FI P V FF V S I G LNMS 288
Cdd:TIGR00932 236 AG VVLSESE Y RHKLESDLE PIG - G V LL P L FF I S V G MSVD 273
RosB
COG4651
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
1-381
1.81e-52
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];
Pssm-ID: 443689 [Multi-domain]
Cd Length: 564
Bit Score: 183.25
E-value: 1.81e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 1 MDYVGSL ALIL IVT AV A G H L SV R MGL P AVI G Q LL S G IIL GP AVL G W V SATSF I KDF AE L GVI I L M F MA GLE SD LK L L KKY 80
Cdd:COG4651 4 TPLITTI ALIL GLA AV L G L L AQ R LRQ P PIV G Y LL A G VLI GP FTP G L V ADVEL I EQL AE I GVI L L L F GV GLE FS LK D L LAV 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 81 WRPS L LV A V L GVV L PVAVIDWCSQ L FHLNAT ESL FL G VTFAAT S VSISVAV L KEL G A LD GKE G TTIL G AAV V D D VLA VL I 160
Cdd:COG4651 84 RKIA L PG A L L QIA L TTLLGFGIAL L LGWSLG ESL VF G LALSLS S TVVLLKL L EDR G E LD TLH G RIAV G WLI V Q D LAV VL M 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 L S L MIS L F G SEVSGG G S hastn LGL S L AIQLA F FVALYF V VKW V V P H L MAVGNALLVPTSIT L MS L V IC F G LS YLA DAI G 240
Cdd:COG4651 164 L V L LPA L A G GGGGLL G T ----- LGL T L LKVAL F VALMLV V GRR V I P W L LHRVARTRSRELFL L AV L A IC L G VA YLA ALF G 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LS AVI GAF F AG IAVGQTD Y HEVIDEHIQ P IGN A v F IPV FFVS I G LNMSFNGF L NDFWFIAVITVAAIAT K IIG A GVGARL 320
Cdd:COG4651 239 LS FAL GAF L AG MVLAESE Y SHQAAAELL P LRD A - F AVL FFVS V G MLFDPSFL L ENPLPVLALLLIVLIG K PLI A FLIVLA 317
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1027832817 321 A G FNWLSGYEI G AGMVSR GE MAL I I A QI G YQGK LLS ADR Y SAVITAI ILT TLIA P L L LRQ A 381
Cdd:COG4651 318 L G YPLRTALLV G LSLAQI GE FSF I L A AL G LSLG LLS EEA Y QLILAVA ILT IALS P Y L IAL A 378
Na_H_Exchanger
pfam00999
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
7-384
1.37e-45
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain]
Cd Length: 377
Bit Score: 160.88
E-value: 1.37e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 7 LA L ILIVTAV A GH L SV R MG LP AVI G QLLS GI I LGP AV LG WV S - ATSFIKDFAE LG VII L M F M AGLE S DL KL L K K YWRPS L 85
Cdd:pfam00999 1 IV L LILLALL A PL L AR R LK LP PIV G LIIA GI L LGP SG LG LI S e VDEDLEVLSN LG LPP L L F L AGLE L DL RE L R K NGGSI L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 86 L V A V LGV VL P VAV I DWC -- SQLFHLNAT E S L FL G VTFA ATS VSISV A V LKELG ALDGKE GT TI LG AA V VD D VL AV LI L SL 163
Cdd:pfam00999 81 L L A L LGV LI P FVL I GLL ly LLGLGIPLL E A L LF G AILS ATS PVVVL A I LKELG RVPERL GT LL LG ES V LN D GV AV VL L AV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 164 MIS L FGSEVS G GGS hastnlg LS L AIQLAFFVALYFVVKWVVPH L MAVGNALLVPTSITLM -- S L VICFGLSY LA D A I G L 241
Cdd:pfam00999 161 LLA L AQGVGG G SDL ------- GW L LLIFLVVAVGGLLLGLLIGW L LRLITRFTDDDRELEV ll V L LLALLAAL LA E A L G V 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 242 S AVI GAF F AG IAVGQTDYHEVID E HIQ P I G NAV F I P V FFV SI GL NMSFNGF L NDF W FIAVITVA AI - ATKII G AGVGA RL 320
Cdd:pfam00999 234 S GIL GAF L AG LVLSEYPFANKLS E KLE P F G YGL F N P L FFV LV GL SLDLSSL L LSV W ILVLLALV AI l LGRFL G VFLLL RL 313
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1027832817 321 A G FNWLSGYE IG A G MVS RG EMA L II A Q IG YQGKLLSADR Y SAV I TAIIL T T L IAPLL L RQAVKR 384
Cdd:pfam00999 314 L G LSLREALI IG F G GLQ RG AVS L AL A A IG PLLGIIAREL Y PLL I VVVLF T V L VQGIT L KPLLFK 377
PRK03562
PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
8-378
2.07e-27
glutathione-regulated potassium-efflux system protein KefC; Provisional
Pssm-ID: 235131 [Multi-domain]
Cd Length: 621
Bit Score: 113.94
E-value: 2.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 8 ALI LIVT AV - AGHLS VR M GL PA V I G Q L LS G I I L GP AV L GW V SATSF I KD FAE L GV IILM F MA GLE S D LKL L K K YW R PSLL 86
Cdd:PRK03562 10 ALI YLGA AV l IVPIA VR L GL GS V L G Y L IA G C I I GP WG L RL V TDVES I LH FAE F GV VLML F VI GLE L D PQR L W K LR R SIFG 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 87 VAV L GV V LPVAVIDWCSQ L FH L NATES L FL G VTF A AT S VS I SVAVLK E LGALDGKE G TTILGAAVVD D VL A VLILS l MI S 166
Cdd:PRK03562 90 GGA L QM V ACGGLLGLFCM L LG L RWQVA L LI G LGL A LS S TA I AMQAMN E RNLMVTQM G RSAFAILLFQ D IA A IPLVA - MI P 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 167 L FGSE vsg G G S HASTNLG LS LAIQLAFFVALYFVVKW V V - P H L MA V GNAL L v PTSI T LMS L VIC FG LSY L ADAI GLS AVI 245
Cdd:PRK03562 169 L LAAS --- G A S TTLGAFA LS ALKVAGALALVVLGGRY V T r P A L RF V ARSG L - REVF T AVA L FLV FG FGL L MEEV GLS MAL 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 246 GAF F AG IAVGQTD Y HEVIDEH I Q P I g NAVFIPV FF VSI G LNMS F NGF L NDFWF I AVITVAAI A T KI IGAGVG AR LA G F -- 323
Cdd:PRK03562 245 GAF L AG VLLASSE Y RHALESD I E P F - KGLLLGL FF IAV G MSID F GTL L ENPLR I LILLLGFL A I KI AMLWLL AR PL G V pr 323
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 324 -- NWLSGYEI G A G mvsr GE M A LIIAQIGYQGKL L SADRYSAVIT A II L TTLIA PLLL 378
Cdd:PRK03562 324 kq RRWFAVLL G Q G ---- GE F A FVVFGAAQMANV L EPEWAKLLTL A VA L SMAAT PLLL 376
PRK03659
PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
2-384
1.28e-23
glutathione-regulated potassium-efflux system protein KefB; Provisional
Pssm-ID: 179625 [Multi-domain]
Cd Length: 601
Bit Score: 102.41
E-value: 1.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 2 D YVGSLA L I L IVTA VA GH L SV R M G LP AV I G Q LL S GI IL GP AV LG WV S ATSF I KD F A ELGV II LMF MA GLE SDLKL L KKYW 81
Cdd:PRK03659 5 D LLTAGV L F L FAAV VA VP L AQ R L G IG AV L G Y LL A GI AI GP WG LG FI S DVDE I LH F S ELGV VF LMF II GLE LNPSK L WQLR 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 82 R PSLL V AVLG V V L PV AV IDWCSQ L FHLNATESLFL G VTF A AT S VSISVAVLK E L G a LDGK E GTT i LG AA V V -- D D VLAVL 159
Cdd:PRK03659 85 R SIFG V GAAQ V L L SA AV LAGLLM L TDFSWQAAVVG G IGL A MS S TAMALQLMR E K G - MNRS E SGQ - LG FS V L lf Q D LAVIP 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 160 I L S L MIS L F G sev S GGGSHASTNL G LSLAIQLAFFVALYFVVKWVVPHLM A V G nall V PTSI T LMS L VICF G LSYLA DA I 239
Cdd:PRK03659 163 A L A L VPL L A G --- S ADEHFDWMKI G MKVLAFAGMLIGGRYLLRPLFRFIA A S G ---- V REVF T AAA L LLVL G SALFM DA L 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 240 GLS AVI G A F F AG IAVGQTD Y HEVIDEH I Q P I g NAVFIPV FF V S I G ln M SF N - G F L NDFWFIAV I T V AA - I A T K IIGAGVG 317
Cdd:PRK03659 236 GLS MAL G T F I AG VLLAESE Y RHELEIA I E P F - KGLLLGL FF I S V G -- M AL N l G V L YTHLLWVL I S V VV l V A V K GLVLYLL 312
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 318 ARL A G FNWLSGYEIGAGMVSR GE M A LIIAQIGYQGK LL SA D RYSAVITAII L TTLIA PLL L r QAVKR 384
Cdd:PRK03659 313 ARL Y G LRSSERMQFAGVLSQG GE F A FVLFSAASSQR LL QG D QMALLLVVVT L SMMTT PLL M - KLIDK 378
PLN03159
PLN03159
cation/H(+) antiporter 15; Provisional
3-377
7.88e-22
cation/H(+) antiporter 15; Provisional
Pssm-ID: 215608 [Multi-domain]
Cd Length: 832
Bit Score: 97.65
E-value: 7.88e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 3 YVGS L A L ILIV T AVAGHLSVRMGL P A VI GQL L S G I ILGP A VLG WVSA --- T S F ------- IKDF A E LG VIILM F MA G L E S 72
Cdd:PLN03159 44 FILQ L T L VVVT T RLLVFILKPFRQ P R VI SEI L G G V ILGP S VLG QSEV fan T I F plrsvmv LETM A N LG LLYFL F LV G V E M 123
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 73 D LKLLKKYWRPS L LV A VL G VV LP VAVIDWC S QL FH L ------ NA T ES LFLGV TFAA T SVSISVAV L K E LGALDGKE G TTI 146
Cdd:PLN03159 124 D ISVIRRTGKKA L AI A IA G MA LP FCIGLAF S FI FH Q vsrnvh QG T FI LFLGV ALSV T AFPVLARI L A E IKLINTEL G RIA 203
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 147 LG AA V V D D VL A VLI L S L M I S L fg S E VS ggg S HASTN L GLS L A i QL AF FVALYF VV KWVVPHLMA vgnal LV P TSI T LMSL 226
Cdd:PLN03159 204 MS AA L V N D MC A WIL L A L A I A L -- A E ND --- S TSLAS L WVL L S - SV AF VLFCFY VV RPGIWWIIR ----- RT P EGE T FSEF 272
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 227 V IC FG L S ------ YLA DAIG LSA V I GAF FA G IAVGQTDYHEVID E HIQPIGNAVFI P V FF VSI GL NMS --- FN G FLNDFW 297
Cdd:PLN03159 273 Y IC LI L T gvmisg FIT DAIG THS V F GAF VF G LVIPNGPLGVTLI E KLEDFVSGLLL P L FF AIS GL KTN vtk IQ G PATWGL 352
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 298 FIA VI TV A AIA t KI I G AGVG A RLAGFNWLS G YEI G AG M VSR G EMAL I IAQI G YQGKL L SADRYSA - V IT A IIL T T LI A P L 376
Cdd:PLN03159 353 LVL VI IM A SAG - KI M G TIII A FFYTMPFRE G ITL G FL M NTK G LVEM I VLNV G RDQEV L DDESFAV m V LV A VAM T A LI T P V 431
.
gi 1027832817 377 L 377
Cdd:PLN03159 432 V 432
PRK10669
PRK10669
putative cation:proton antiport protein; Provisional
4-377
2.79e-19
putative cation:proton antiport protein; Provisional
Pssm-ID: 182633 [Multi-domain]
Cd Length: 558
Bit Score: 89.39
E-value: 2.79e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 4 VG S L A L IL I V tava G H L SV R MGLPAVI G Q LL S G IIL GP AVL G W V SA T SFIKDF AELGVI I LMF MA GL ESD LK L L --- K KY 80
Cdd:PRK10669 12 VG G L V L AF I L ---- G M L AN R LRISPLV G Y LL A G VLA GP FTP G F V AD T KLAPEL AELGVI L LMF GV GL HFS LK D L mav K SI 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 81 WR P SLLVAVLGVV L PVAVIDW csq LFHLNATESLFL G VTFAAT S VSISVAV L K E LGAL D GKE G TTIL G AAV V D D VLA VL I 160
Cdd:PRK10669 88 AI P GAIAQIAVAT L LGMALSA --- VLGWSLMTGIVF G LCLSTA S TVVLLRA L E E RQLI D SQR G QIAI G WLI V E D LVM VL T 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 L S L MISLF G SEVS G GGSH A S -- TN LG LSLAIQL AF FVALYF V VKWV VP HLM A ---- V G NAL L VPT S ITLMS L V I C FG LSY 234
Cdd:PRK10669 165 L V L LPAVA G MMEQ G DVGF A T la VD LG ITIGKVI AF IAIMML V GRRL VP WIL A rsaa T G SRE L FTL S VLALA L G I A FG AVE 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 235 L A D A igl S AVI GAFFAG IAVGQTDYHEVIDEHIQ P IGN A v F IPV FFVS I G ln M S F NGFLNDFWFI AV ITVA AI A tk II G A 314
Cdd:PRK10669 245 L F D V --- S FAL GAFFAG MVLNESELSHRAAHDTL P LRD A - F AVL FFVS V G -- M L F DPMILIQQPL AV LATL AI I -- VF G K 316
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 315 GVG A ---- RL A G FNWLSGYE I G A GMVSR GE M A L I I A QI G YQGK LL SADRYSA V ITAI IL TTLIA P L L 377
Cdd:PRK10669 317 SLA A fflv RL F G HSRRTALT I A A SLAQI GE F A F I L A GL G MALN LL PQAGQNL V LAGA IL SIMLN P V L 383
NhaP
COG0025
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
1-307
3.69e-18
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 439796 [Multi-domain]
Cd Length: 506
Bit Score: 85.79
E-value: 3.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 1 M DYVGSLA L I L IVTAVAGH L SV R MG LPA VIGQ LL S GI I LGP a V LG WV -- SATSFIKDFA EL GVII L M F M A G L ES DL KL L K 78
Cdd:COG0025 1 M ELLLLIL L L L LLGLLSQW L AR R LK LPA PLLL LL A GI L LGP - G LG LE ld PELGDLEPLL EL FLPP L L F E A A L NL DL RE L R 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 79 KYW RP S L LV AV L GV V L PVAVIDW - CSQ L FH L NATES L F LG VTF A A T SVSISVAV L KE LG a LDGKEG T TIL G AAVVD D VL A 157
Cdd:COG0025 80 RNG RP I L RL AV V GV L L TTLAVAL a AHW L LG L PLAAA L L LG AIL A P T DPVAVSPI L RR LG - VPKRLR T ILE G ESLLN D AT A 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 158 VLILS L MISLFGSE v SGGGSH A STNLG L SLAIQLAFFVA L YFVVKWVVPH L MA vgnallv P TSIT L MS L VIC F GLSY LA D 237
Cdd:COG0025 159 LVLFV L ALAAALGG - GFSLGE A LLDFL L AILGGILVGLL L GWLLGRLLRR L PD ------- P LLEI L LT L ALP F LAYL LA E 230
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 238 A IGL S A V IGAFF AG IAV G QTDYHEVID E HIQPIGN ------ AVFIPVF FV SI G LNMSFNGFLNDFWFIAVITVA A I 307
Cdd:COG0025 231 A LHG S G V LAVVV AG LVL G NAGRRSLSP E TRLQLLE fwetle FLLNSLL FV LL G AQLPLILLGALGLGGILLVLL A L 306
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01