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Conserved domains on  [gi|1027832817|ref|WP_063730259|]
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cation:proton antiporter [Lactiplantibacillus plantarum]

Protein Classification

cation:proton antiporter( domain architecture ID 10001451)

cation:proton antiporter functions in maintaining cation homeostasis and the pH of actively metabolizing cells; it may also be involved in regulating cell volume

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
KefB COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
1-386 3.99e-83

Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];


:

Pssm-ID: 440243 [Multi-domain]  Cd Length: 384  Bit Score: 258.54  E-value: 3.99e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   1 MDYVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKY 80
Cdd:COG0475     3 ASLLLQLGLLLLAAVLAGLLARRLGLPSVLGYILAGILLGPSGLGLIEDSEALELLAELGVVLLLFLIGLELDLKRLRKM 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  81 WRPSLLVAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLI 160
Cdd:COG0475    83 GRRALGIGLLQVLLPFLLGFLLALLLGLSLAAALFLGAALAATSTAIVLKVLKELGLLKTPLGQLILGVALFDDIAAILL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 LSLMISLfgsevsGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLMSLVICFGLSYLADAIG 240
Cdd:COG0475   163 LALVPAL------AGGGSVAGSLLLALLKALLFLALLLLVGRYLLRRLFRLVARTRSRELFLLFALLLVLLAAALAELLG 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNaVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAIATKIIGAGVGARL 320
Cdd:COG0475   237 LSAALGAFLAGLVLAESEYRHELEEKIEPFGD-LFLPLFFVSVGLSLDLSALLSNPLLALLLVLAAIVGKLLGAYLAARL 315
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 321 AGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLRQAVKRQR 386
Cdd:COG0475   316 FGLSRREALRIGLLLAPRGEFALVLASLGLSAGLISPELFAALVLVVLLTTLLTPLLLRLALRLAE 381
 
Name Accession Description Interval E-value
KefB COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
1-386 3.99e-83

Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];


Pssm-ID: 440243 [Multi-domain]  Cd Length: 384  Bit Score: 258.54  E-value: 3.99e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   1 MDYVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKY 80
Cdd:COG0475     3 ASLLLQLGLLLLAAVLAGLLARRLGLPSVLGYILAGILLGPSGLGLIEDSEALELLAELGVVLLLFLIGLELDLKRLRKM 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  81 WRPSLLVAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLI 160
Cdd:COG0475    83 GRRALGIGLLQVLLPFLLGFLLALLLGLSLAAALFLGAALAATSTAIVLKVLKELGLLKTPLGQLILGVALFDDIAAILL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 LSLMISLfgsevsGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLMSLVICFGLSYLADAIG 240
Cdd:COG0475   163 LALVPAL------AGGGSVAGSLLLALLKALLFLALLLLVGRYLLRRLFRLVARTRSRELFLLFALLLVLLAAALAELLG 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNaVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAIATKIIGAGVGARL 320
Cdd:COG0475   237 LSAALGAFLAGLVLAESEYRHELEEKIEPFGD-LFLPLFFVSVGLSLDLSALLSNPLLALLLVLAAIVGKLLGAYLAARL 315
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 321 AGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLRQAVKRQR 386
Cdd:COG0475   316 FGLSRREALRIGLLLAPRGEFALVLASLGLSAGLISPELFAALVLVVLLTTLLTPLLLRLALRLAE 381
2a37 TIGR00932
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
11-288 1.70e-55

transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273348 [Multi-domain]  Cd Length: 273  Bit Score: 183.62  E-value: 1.70e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  11 LIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKYWRPSLLVAVL 90
Cdd:TIGR00932   1 LLAAVLAVPLSRRLGIPSVLGYLLAGVLIGPSGLGLISNVEGVNHLAEFGVILLMFLIGLELDLERLWKLRKAAFGVGVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  91 GVVLPVAVIDWC-SQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLILSLMISLfg 169
Cdd:TIGR00932  81 QVLVPGVLLGLLlGHLLGLALGAAVVIGIILALSSTAVVVQVLKERGLLKTPFGQTVLGILLFQDIAVVPLLALLPLL-- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 170 sevSGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLMSLVICFGLSYLADAIGLSAVIGAFF 249
Cdd:TIGR00932 159 ---ATSASTEHVALALLLLKVFLAFLLLVLLGRWLLRPVLRLTAELRPSELFTAGSLLLMFGSAYFADLLGLSMALGAFL 235
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1027832817 250 AGIAVGQTDYHEVIDEHIQPIGnAVFIPVFFVSIGLNMS 288
Cdd:TIGR00932 236 AGVVLSESEYRHKLESDLEPIG-GVLLPLFFISVGMSVD 273
Na_H_Exchanger pfam00999
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
7-384 1.37e-45

Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.


Pssm-ID: 425982 [Multi-domain]  Cd Length: 377  Bit Score: 160.88  E-value: 1.37e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   7 LALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVS-ATSFIKDFAELGVIILMFMAGLESDLKLLKKYWRPSL 85
Cdd:pfam00999   1 IVLLILLALLAPLLARRLKLPPIVGLIIAGILLGPSGLGLISeVDEDLEVLSNLGLPPLLFLAGLELDLRELRKNGGSIL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  86 LVAVLGVVLPVAVIDWC--SQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLILSL 163
Cdd:pfam00999  81 LLALLGVLIPFVLIGLLlyLLGLGIPLLEALLFGAILSATSPVVVLAILKELGRVPERLGTLLLGESVLNDGVAVVLLAV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 164 MISLFGSEVSGGGShastnlgLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLM--SLVICFGLSYLADAIGL 241
Cdd:pfam00999 161 LLALAQGVGGGSDL-------GWLLLIFLVVAVGGLLLGLLIGWLLRLITRFTDDDRELEVllVLLLALLAALLAEALGV 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 242 SAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNAVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAI-ATKIIGAGVGARL 320
Cdd:pfam00999 234 SGILGAFLAGLVLSEYPFANKLSEKLEPFGYGLFNPLFFVLVGLSLDLSSLLLSVWILVLLALVAIlLGRFLGVFLLLRL 313
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1027832817 321 AGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLRQAVKR 384
Cdd:pfam00999 314 LGLSLREALIIGFGGLQRGAVSLALAAIGPLLGIIARELYPLLIVVVLFTVLVQGITLKPLLFK 377
PRK03562 PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
8-378 2.07e-27

glutathione-regulated potassium-efflux system protein KefC; Provisional


Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 113.94  E-value: 2.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   8 ALILIVTAV-AGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKYWRPSLL 86
Cdd:PRK03562   10 ALIYLGAAVlIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDVESILHFAEFGVVLMLFVIGLELDPQRLWKLRRSIFG 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  87 VAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLILSlMIS 166
Cdd:PRK03562   90 GGALQMVACGGLLGLFCMLLGLRWQVALLIGLGLALSSTAIAMQAMNERNLMVTQMGRSAFAILLFQDIAAIPLVA-MIP 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 167 LFGSEvsgGGSHASTNLGLSLAIQLAFFVALYFVVKWVV-PHLMAVGNALLvPTSITLMSLVICFGLSYLADAIGLSAVI 245
Cdd:PRK03562  169 LLAAS---GASTTLGAFALSALKVAGALALVVLGGRYVTrPALRFVARSGL-REVFTAVALFLVFGFGLLMEEVGLSMAL 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 246 GAFFAGIAVGQTDYHEVIDEHIQPIgNAVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAIATKIIGAGVGARLAGF-- 323
Cdd:PRK03562  245 GAFLAGVLLASSEYRHALESDIEPF-KGLLLGLFFIAVGMSIDFGTLLENPLRILILLLGFLAIKIAMLWLLARPLGVpr 323
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 324 --NWLSGYEIGAGmvsrGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLL 378
Cdd:PRK03562  324 kqRRWFAVLLGQG----GEFAFVVFGAAQMANVLEPEWAKLLTLAVALSMAATPLLL 376
 
Name Accession Description Interval E-value
KefB COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
1-386 3.99e-83

Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];


Pssm-ID: 440243 [Multi-domain]  Cd Length: 384  Bit Score: 258.54  E-value: 3.99e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   1 MDYVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKY 80
Cdd:COG0475     3 ASLLLQLGLLLLAAVLAGLLARRLGLPSVLGYILAGILLGPSGLGLIEDSEALELLAELGVVLLLFLIGLELDLKRLRKM 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  81 WRPSLLVAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLI 160
Cdd:COG0475    83 GRRALGIGLLQVLLPFLLGFLLALLLGLSLAAALFLGAALAATSTAIVLKVLKELGLLKTPLGQLILGVALFDDIAAILL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 LSLMISLfgsevsGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLMSLVICFGLSYLADAIG 240
Cdd:COG0475   163 LALVPAL------AGGGSVAGSLLLALLKALLFLALLLLVGRYLLRRLFRLVARTRSRELFLLFALLLVLLAAALAELLG 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNaVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAIATKIIGAGVGARL 320
Cdd:COG0475   237 LSAALGAFLAGLVLAESEYRHELEEKIEPFGD-LFLPLFFVSVGLSLDLSALLSNPLLALLLVLAAIVGKLLGAYLAARL 315
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 321 AGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLRQAVKRQR 386
Cdd:COG0475   316 FGLSRREALRIGLLLAPRGEFALVLASLGLSAGLISPELFAALVLVVLLTTLLTPLLLRLALRLAE 381
2a37 TIGR00932
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
11-288 1.70e-55

transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273348 [Multi-domain]  Cd Length: 273  Bit Score: 183.62  E-value: 1.70e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  11 LIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKYWRPSLLVAVL 90
Cdd:TIGR00932   1 LLAAVLAVPLSRRLGIPSVLGYLLAGVLIGPSGLGLISNVEGVNHLAEFGVILLMFLIGLELDLERLWKLRKAAFGVGVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  91 GVVLPVAVIDWC-SQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLILSLMISLfg 169
Cdd:TIGR00932  81 QVLVPGVLLGLLlGHLLGLALGAAVVIGIILALSSTAVVVQVLKERGLLKTPFGQTVLGILLFQDIAVVPLLALLPLL-- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 170 sevSGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLMSLVICFGLSYLADAIGLSAVIGAFF 249
Cdd:TIGR00932 159 ---ATSASTEHVALALLLLKVFLAFLLLVLLGRWLLRPVLRLTAELRPSELFTAGSLLLMFGSAYFADLLGLSMALGAFL 235
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1027832817 250 AGIAVGQTDYHEVIDEHIQPIGnAVFIPVFFVSIGLNMS 288
Cdd:TIGR00932 236 AGVVLSESEYRHKLESDLEPIG-GVLLPLFFISVGMSVD 273
RosB COG4651
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
1-381 1.81e-52

Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];


Pssm-ID: 443689 [Multi-domain]  Cd Length: 564  Bit Score: 183.25  E-value: 1.81e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   1 MDYVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKY 80
Cdd:COG4651     4 TPLITTIALILGLAAVLGLLAQRLRQPPIVGYLLAGVLIGPFTPGLVADVELIEQLAEIGVILLLFGVGLEFSLKDLLAV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  81 WRPSLLVAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLI 160
Cdd:COG4651    84 RKIALPGALLQIALTTLLGFGIALLLGWSLGESLVFGLALSLSSTVVLLKLLEDRGELDTLHGRIAVGWLIVQDLAVVLM 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 LSLMISLFGSEVSGGGShastnLGLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLMSLVICFGLSYLADAIG 240
Cdd:COG4651   164 LVLLPALAGGGGGLLGT-----LGLTLLKVALFVALMLVVGRRVIPWLLHRVARTRSRELFLLAVLAICLGVAYLAALFG 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 241 LSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNAvFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAIATKIIGAGVGARL 320
Cdd:COG4651   239 LSFALGAFLAGMVLAESEYSHQAAAELLPLRDA-FAVLFFVSVGMLFDPSFLLENPLPVLALLLIVLIGKPLIAFLIVLA 317
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1027832817 321 AGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLRQA 381
Cdd:COG4651   318 LGYPLRTALLVGLSLAQIGEFSFILAALGLSLGLLSEEAYQLILAVAILTIALSPYLIALA 378
Na_H_Exchanger pfam00999
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
7-384 1.37e-45

Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.


Pssm-ID: 425982 [Multi-domain]  Cd Length: 377  Bit Score: 160.88  E-value: 1.37e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   7 LALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVS-ATSFIKDFAELGVIILMFMAGLESDLKLLKKYWRPSL 85
Cdd:pfam00999   1 IVLLILLALLAPLLARRLKLPPIVGLIIAGILLGPSGLGLISeVDEDLEVLSNLGLPPLLFLAGLELDLRELRKNGGSIL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  86 LVAVLGVVLPVAVIDWC--SQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLILSL 163
Cdd:pfam00999  81 LLALLGVLIPFVLIGLLlyLLGLGIPLLEALLFGAILSATSPVVVLAILKELGRVPERLGTLLLGESVLNDGVAVVLLAV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 164 MISLFGSEVSGGGShastnlgLSLAIQLAFFVALYFVVKWVVPHLMAVGNALLVPTSITLM--SLVICFGLSYLADAIGL 241
Cdd:pfam00999 161 LLALAQGVGGGSDL-------GWLLLIFLVVAVGGLLLGLLIGWLLRLITRFTDDDRELEVllVLLLALLAALLAEALGV 233
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 242 SAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNAVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAI-ATKIIGAGVGARL 320
Cdd:pfam00999 234 SGILGAFLAGLVLSEYPFANKLSEKLEPFGYGLFNPLFFVLVGLSLDLSSLLLSVWILVLLALVAIlLGRFLGVFLLLRL 313
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1027832817 321 AGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLRQAVKR 384
Cdd:pfam00999 314 LGLSLREALIIGFGGLQRGAVSLALAAIGPLLGIIARELYPLLIVVVLFTVLVQGITLKPLLFK 377
PRK03562 PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
8-378 2.07e-27

glutathione-regulated potassium-efflux system protein KefC; Provisional


Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 113.94  E-value: 2.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   8 ALILIVTAV-AGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKYWRPSLL 86
Cdd:PRK03562   10 ALIYLGAAVlIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDVESILHFAEFGVVLMLFVIGLELDPQRLWKLRRSIFG 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  87 VAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLILSlMIS 166
Cdd:PRK03562   90 GGALQMVACGGLLGLFCMLLGLRWQVALLIGLGLALSSTAIAMQAMNERNLMVTQMGRSAFAILLFQDIAAIPLVA-MIP 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 167 LFGSEvsgGGSHASTNLGLSLAIQLAFFVALYFVVKWVV-PHLMAVGNALLvPTSITLMSLVICFGLSYLADAIGLSAVI 245
Cdd:PRK03562  169 LLAAS---GASTTLGAFALSALKVAGALALVVLGGRYVTrPALRFVARSGL-REVFTAVALFLVFGFGLLMEEVGLSMAL 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 246 GAFFAGIAVGQTDYHEVIDEHIQPIgNAVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAIATKIIGAGVGARLAGF-- 323
Cdd:PRK03562  245 GAFLAGVLLASSEYRHALESDIEPF-KGLLLGLFFIAVGMSIDFGTLLENPLRILILLLGFLAIKIAMLWLLARPLGVpr 323
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 324 --NWLSGYEIGAGmvsrGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLL 378
Cdd:PRK03562  324 kqRRWFAVLLGQG----GEFAFVVFGAAQMANVLEPEWAKLLTLAVALSMAATPLLL 376
PRK03659 PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
2-384 1.28e-23

glutathione-regulated potassium-efflux system protein KefB; Provisional


Pssm-ID: 179625 [Multi-domain]  Cd Length: 601  Bit Score: 102.41  E-value: 1.28e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   2 DYVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLLKKYW 81
Cdd:PRK03659    5 DLLTAGVLFLFAAVVAVPLAQRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLR 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  82 RPSLLVAVLGVVLPVAVIDWCSQLFHLNATESLFLGVTFAATSVSISVAVLKELGaLDGKEGTTiLGAAVV--DDVLAVL 159
Cdd:PRK03659   85 RSIFGVGAAQVLLSAAVLAGLLMLTDFSWQAAVVGGIGLAMSSTAMALQLMREKG-MNRSESGQ-LGFSVLlfQDLAVIP 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 160 ILSLMISLFGsevSGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAVGnallVPTSITLMSLVICFGLSYLADAI 239
Cdd:PRK03659  163 ALALVPLLAG---SADEHFDWMKIGMKVLAFAGMLIGGRYLLRPLFRFIAASG----VREVFTAAALLLVLGSALFMDAL 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 240 GLSAVIGAFFAGIAVGQTDYHEVIDEHIQPIgNAVFIPVFFVSIGlnMSFN-GFLNDFWFIAVITVAA-IATKIIGAGVG 317
Cdd:PRK03659  236 GLSMALGTFIAGVLLAESEYRHELEIAIEPF-KGLLLGLFFISVG--MALNlGVLYTHLLWVLISVVVlVAVKGLVLYLL 312
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 318 ARLAGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLLLrQAVKR 384
Cdd:PRK03659  313 ARLYGLRSSERMQFAGVLSQGGEFAFVLFSAASSQRLLQGDQMALLLVVVTLSMMTTPLLM-KLIDK 378
PLN03159 PLN03159
cation/H(+) antiporter 15; Provisional
3-377 7.88e-22

cation/H(+) antiporter 15; Provisional


Pssm-ID: 215608 [Multi-domain]  Cd Length: 832  Bit Score: 97.65  E-value: 7.88e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   3 YVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSA---TSF-------IKDFAELGVIILMFMAGLES 72
Cdd:PLN03159   44 FILQLTLVVVTTRLLVFILKPFRQPRVISEILGGVILGPSVLGQSEVfanTIFplrsvmvLETMANLGLLYFLFLVGVEM 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  73 DLKLLKKYWRPSLLVAVLGVVLPVAVIDWCSQLFHL------NATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTI 146
Cdd:PLN03159  124 DISVIRRTGKKALAIAIAGMALPFCIGLAFSFIFHQvsrnvhQGTFILFLGVALSVTAFPVLARILAEIKLINTELGRIA 203
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 147 LGAAVVDDVLAVLILSLMISLfgSEVSgggSHASTNLGLSLAiQLAFFVALYFVVKWVVPHLMAvgnalLVPTSITLMSL 226
Cdd:PLN03159  204 MSAALVNDMCAWILLALAIAL--AEND---STSLASLWVLLS-SVAFVLFCFYVVRPGIWWIIR-----RTPEGETFSEF 272
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 227 VICFGLS------YLADAIGLSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNAVFIPVFFVSIGLNMS---FNGFLNDFW 297
Cdd:PLN03159  273 YICLILTgvmisgFITDAIGTHSVFGAFVFGLVIPNGPLGVTLIEKLEDFVSGLLLPLFFAISGLKTNvtkIQGPATWGL 352
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 298 FIAVITVAAIAtKIIGAGVGARLAGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSA-VITAIILTTLIAPL 376
Cdd:PLN03159  353 LVLVIIMASAG-KIMGTIIIAFFYTMPFREGITLGFLMNTKGLVEMIVLNVGRDQEVLDDESFAVmVLVAVAMTALITPV 431

                  .
gi 1027832817 377 L 377
Cdd:PLN03159  432 V 432
PRK10669 PRK10669
putative cation:proton antiport protein; Provisional
4-377 2.79e-19

putative cation:proton antiport protein; Provisional


Pssm-ID: 182633 [Multi-domain]  Cd Length: 558  Bit Score: 89.39  E-value: 2.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   4 VGSLALILIVtavaGHLSVRMGLPAVIGQLLSGIILGPAVLGWVSATSFIKDFAELGVIILMFMAGLESDLKLL---KKY 80
Cdd:PRK10669   12 VGGLVLAFIL----GMLANRLRISPLVGYLLAGVLAGPFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLmavKSI 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  81 WRPSLLVAVLGVVLPVAVIDWcsqLFHLNATESLFLGVTFAATSVSISVAVLKELGALDGKEGTTILGAAVVDDVLAVLI 160
Cdd:PRK10669   88 AIPGAIAQIAVATLLGMALSA---VLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLVMVLT 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 161 LSLMISLFGSEVSGGGSHAS--TNLGLSLAIQLAFFVALYFVVKWVVPHLMA----VGNALLVPTSITLMSLVICFGLSY 234
Cdd:PRK10669  165 LVLLPAVAGMMEQGDVGFATlaVDLGITIGKVIAFIAIMMLVGRRLVPWILArsaaTGSRELFTLSVLALALGIAFGAVE 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 235 LADAiglSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGNAvFIPVFFVSIGlnMSFNGFLNDFWFIAVITVAAIAtkIIGA 314
Cdd:PRK10669  245 LFDV---SFALGAFFAGMVLNESELSHRAAHDTLPLRDA-FAVLFFVSVG--MLFDPMILIQQPLAVLATLAII--VFGK 316
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1027832817 315 GVGA----RLAGFNWLSGYEIGAGMVSRGEMALIIAQIGYQGKLLSADRYSAVITAIILTTLIAPLL 377
Cdd:PRK10669  317 SLAAfflvRLFGHSRRTALTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVL 383
NhaP COG0025
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
1-307 3.69e-18

NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];


Pssm-ID: 439796 [Multi-domain]  Cd Length: 506  Bit Score: 85.79  E-value: 3.69e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817   1 MDYVGSLALILIVTAVAGHLSVRMGLPAVIGQLLSGIILGPaVLGWV--SATSFIKDFAELGVIILMFMAGLESDLKLLK 78
Cdd:COG0025     1 MELLLLILLLLLLGLLSQWLARRLKLPAPLLLLLAGILLGP-GLGLEldPELGDLEPLLELFLPPLLFEAALNLDLRELR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817  79 KYWRPSLLVAVLGVVLPVAVIDW-CSQLFHLNATESLFLGVTFAATSVSISVAVLKELGaLDGKEGTTILGAAVVDDVLA 157
Cdd:COG0025    80 RNGRPILRLAVVGVLLTTLAVALaAHWLLGLPLAAALLLGAILAPTDPVAVSPILRRLG-VPKRLRTILEGESLLNDATA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1027832817 158 VLILSLMISLFGSEvSGGGSHASTNLGLSLAIQLAFFVALYFVVKWVVPHLMAvgnallvPTSITLMSLVICFGLSYLAD 237
Cdd:COG0025   159 LVLFVLALAAALGG-GFSLGEALLDFLLAILGGILVGLLLGWLLGRLLRRLPD-------PLLEILLTLALPFLAYLLAE 230
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1027832817 238 AIGLSAVIGAFFAGIAVGQTDYHEVIDEHIQPIGN------AVFIPVFFVSIGLNMSFNGFLNDFWFIAVITVAAI 307
Cdd:COG0025   231 ALHGSGVLAVVVAGLVLGNAGRRSLSPETRLQLLEfwetleFLLNSLLFVLLGAQLPLILLGALGLGGILLVLLAL 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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