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Conserved domains on  [gi|1026923913|gb|OAF71997|]
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hypothetical protein A3Q56_00221 [Intoshia linei]

Protein Classification

eukaryotic translation initiation factor 3 subunit L( domain architecture ID 10563035)

eukaryotic translation initiation factor 3 subunit L (EIF3L) is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Paf67 pfam10255
RNA polymerase I-associated factor PAF67; RNA polymerase I is a multisubunit enzyme and its ...
 91-476 1.51e-122

RNA polymerase I-associated factor PAF67; RNA polymerase I is a multisubunit enzyme and its transcription competence is dependent on the presence of PAF67. This family of proteins is conserved from worms to humans.


:

Pssm-ID: 463028  Cd Length: 399  Bit Score: 363.85  E-value: 1.51e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913  91 RIDSYNNYINIFQGLLLANDPVDLHLPSIWLWNMVTEFIYQFQAFTQFRYRNIEKT-----LNKDTSNAWNVHSVIKICV 165
Cdd:pfam10255   2 RFESWENYCDLFNYILNSDGPVNLELPNQWLWDIIDEFVYQFQSFCQYRSKLKNKTeeeiaLLEENPQVWNVYSVLNVLH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 166 LMCDRANINNQLILLNEGEDRMNAAGKFGCRDIYYELGLFSLIGLLRINCLLADYQHALSYVANID---RIILSticKVP 242
Cdd:pfam10255  82 SLIQKSKINEQLEAEKEGVDPDEVAGEFGSSPLYKMLGYFSLIGLLRVHVLLGDYYLALKVLENIDlnkKALYS---KVP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 243 ECIINYYYYVSFCYFMLRRYTEAI---SYICAAIN----------YeeeQSSTINKgiynekkqLVDKMFYILAMSLALN 309
Cdd:pfam10255 159 ACHVTTYYYVGFAYLMLRRYKDAIrtfSSILLYIQrtkqlyqtrsY---QYDQINK--------QNDQMYALLAICLALC 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 310 PLQIDESIMHDMKNRLSDRYGKLLAGDLKEFENCFKTSCPKFVSPFIPTDSEMCERTML-PINHQLEFFLNEViaSKTQL 388
Cdd:pfam10255 228 PQRLDESIHSQLKEKYGEKLYKMQRGDLQAFEELFLFACPKFISPVSPDYEDPNANEAKePTQRQLKVFLKEV--KQQKL 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 389 MPELRSYIGFYSTIPIKRLSYFMQQPEEKIYQYLMCCKHRANN------SQDLENEKKNKAKLDFYIDGDMIHIANTTVS 462
Cdd:pfam10255 306 LPTLRSYLKLYTTIPLEKLASFLDVDEEELRSQLLCFKHKMRQlvwtegGSLLDGEFQSTSDLDFYIDGDMIHIAETKVA 385

                         410
                  ....*....|....
gi 1026923913 463 KKTSDIFIRQIKNL 476
Cdd:pfam10255 386 RRYGDYFIRQIAKF 399
 
Name Accession Description Interval E-value
Paf67 pfam10255
RNA polymerase I-associated factor PAF67; RNA polymerase I is a multisubunit enzyme and its ...
 91-476 1.51e-122

RNA polymerase I-associated factor PAF67; RNA polymerase I is a multisubunit enzyme and its transcription competence is dependent on the presence of PAF67. This family of proteins is conserved from worms to humans.


Pssm-ID: 463028  Cd Length: 399  Bit Score: 363.85  E-value: 1.51e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913  91 RIDSYNNYINIFQGLLLANDPVDLHLPSIWLWNMVTEFIYQFQAFTQFRYRNIEKT-----LNKDTSNAWNVHSVIKICV 165
Cdd:pfam10255   2 RFESWENYCDLFNYILNSDGPVNLELPNQWLWDIIDEFVYQFQSFCQYRSKLKNKTeeeiaLLEENPQVWNVYSVLNVLH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 166 LMCDRANINNQLILLNEGEDRMNAAGKFGCRDIYYELGLFSLIGLLRINCLLADYQHALSYVANID---RIILSticKVP 242
Cdd:pfam10255  82 SLIQKSKINEQLEAEKEGVDPDEVAGEFGSSPLYKMLGYFSLIGLLRVHVLLGDYYLALKVLENIDlnkKALYS---KVP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 243 ECIINYYYYVSFCYFMLRRYTEAI---SYICAAIN----------YeeeQSSTINKgiynekkqLVDKMFYILAMSLALN 309
Cdd:pfam10255 159 ACHVTTYYYVGFAYLMLRRYKDAIrtfSSILLYIQrtkqlyqtrsY---QYDQINK--------QNDQMYALLAICLALC 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 310 PLQIDESIMHDMKNRLSDRYGKLLAGDLKEFENCFKTSCPKFVSPFIPTDSEMCERTML-PINHQLEFFLNEViaSKTQL 388
Cdd:pfam10255 228 PQRLDESIHSQLKEKYGEKLYKMQRGDLQAFEELFLFACPKFISPVSPDYEDPNANEAKePTQRQLKVFLKEV--KQQKL 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 389 MPELRSYIGFYSTIPIKRLSYFMQQPEEKIYQYLMCCKHRANN------SQDLENEKKNKAKLDFYIDGDMIHIANTTVS 462
Cdd:pfam10255 306 LPTLRSYLKLYTTIPLEKLASFLDVDEEELRSQLLCFKHKMRQlvwtegGSLLDGEFQSTSDLDFYIDGDMIHIAETKVA 385

                         410
                  ....*....|....
gi 1026923913 463 KKTSDIFIRQIKNL 476
Cdd:pfam10255 386 RRYGDYFIRQIAKF 399
 
Name Accession Description Interval E-value
Paf67 pfam10255
RNA polymerase I-associated factor PAF67; RNA polymerase I is a multisubunit enzyme and its ...
 91-476 1.51e-122

RNA polymerase I-associated factor PAF67; RNA polymerase I is a multisubunit enzyme and its transcription competence is dependent on the presence of PAF67. This family of proteins is conserved from worms to humans.


Pssm-ID: 463028  Cd Length: 399  Bit Score: 363.85  E-value: 1.51e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913  91 RIDSYNNYINIFQGLLLANDPVDLHLPSIWLWNMVTEFIYQFQAFTQFRYRNIEKT-----LNKDTSNAWNVHSVIKICV 165
Cdd:pfam10255   2 RFESWENYCDLFNYILNSDGPVNLELPNQWLWDIIDEFVYQFQSFCQYRSKLKNKTeeeiaLLEENPQVWNVYSVLNVLH 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 166 LMCDRANINNQLILLNEGEDRMNAAGKFGCRDIYYELGLFSLIGLLRINCLLADYQHALSYVANID---RIILSticKVP 242
Cdd:pfam10255  82 SLIQKSKINEQLEAEKEGVDPDEVAGEFGSSPLYKMLGYFSLIGLLRVHVLLGDYYLALKVLENIDlnkKALYS---KVP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 243 ECIINYYYYVSFCYFMLRRYTEAI---SYICAAIN----------YeeeQSSTINKgiynekkqLVDKMFYILAMSLALN 309
Cdd:pfam10255 159 ACHVTTYYYVGFAYLMLRRYKDAIrtfSSILLYIQrtkqlyqtrsY---QYDQINK--------QNDQMYALLAICLALC 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 310 PLQIDESIMHDMKNRLSDRYGKLLAGDLKEFENCFKTSCPKFVSPFIPTDSEMCERTML-PINHQLEFFLNEViaSKTQL 388
Cdd:pfam10255 228 PQRLDESIHSQLKEKYGEKLYKMQRGDLQAFEELFLFACPKFISPVSPDYEDPNANEAKePTQRQLKVFLKEV--KQQKL 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1026923913 389 MPELRSYIGFYSTIPIKRLSYFMQQPEEKIYQYLMCCKHRANN------SQDLENEKKNKAKLDFYIDGDMIHIANTTVS 462
Cdd:pfam10255 306 LPTLRSYLKLYTTIPLEKLASFLDVDEEELRSQLLCFKHKMRQlvwtegGSLLDGEFQSTSDLDFYIDGDMIHIAETKVA 385

                         410
                  ....*....|....
gi 1026923913 463 KKTSDIFIRQIKNL 476
Cdd:pfam10255 386 RRYGDYFIRQIAKF 399
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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